Contact Information:

Media Contact

Kerstin Hellwig
k.hellwig@klinikum-bochum.de

Twitter: JAMA_current

http://www.jamamedia.org




Kredyty mieszkaniowe Kredyty mieszkaniowe

Sprawdź aktualny ranking najlepszych kredytów mieszkaniowych w Polsce - atrakcyjne kredytowanie nieruchomości.

PRESS-NEWS.org - Press Release Distribution
FREE PRESS RELEASES DISTRIBUTION
RSS - Press News Release
Add Press Release

Exclusive breastfeeding and the effect on postpartum multiple sclerosis relapses


2015-08-31
(Press-News.org) Women with multiple sclerosis (MS) who intended to breastfeed their infants exclusively for two months had a lower risk of relapse during the first six months after giving birth compared with women who did not breastfeed exclusively , according to an article published online by JAMA Neurology.

About 20 percent to 30 percent of women with MS experience a relapse within the first three to four months after giving birth and there are no interventions for effective prevention of postpartum relapse. The effect of exclusive breastfeeding on postpartum risk of MS relapse is controversial with conflicting study results.

Kerstin Hellwig, M.D., of Ruhr-University Bochum, Germany, and coauthors analyzed data from 201 pregnant women with MS collected from 2008 to June 2012 with one-year follow-up postpartum in the nationwide German MS and pregnancy registry. Exclusive breastfeeding was defined as no regular replacement of breastfeeding meals with supplemental feedings for at least two months compared with nonexclusive breastfeeding, which was partial or no breastfeeding.

Of the 201 women, 120 (59.7 percent) intended to breastfeed exclusively for at least two months, 42 women (20.9 percent) combined breastfeeding with supplemental feedings within the first two months after giving birth, and 39 women (19.4 percent) did not breastfeed. Most women [178 (88.6 percent)] had used disease-modifying therapy (DMT) agents before pregnancy.

The authors report that 31 women (38.3 percent) who did not breastfeed exclusively had MS relapse within the first six months postpartum compared with 29 women (24.2 percent) who intended to breastfeed exclusively for at least two months.

The authors note the effect of exclusive breastfeeding "seems to be plausible" since disease activity returned in the second half of the postpartum year in exclusively breastfeeding women, corresponding to the introduction of supplemental feedings and the return of menstruation. The introduction of regular formula feedings or solid food to an infant leads to a change in a woman's hormonal status resulting in the return to ovulation.

The authors note the main limitation of their study was the selection bias inherent to voluntary registries and reflected in the high proportion of women receiving DMT.

"Taken together, our findings indicate that women with MS should be supported if they choose to breastfeed exclusively since it clearly does not increase the risk of postpartum relapse. Relapse in the first six months postpartum may be diminished by exclusive breastfeeding, but once regular feedings are introduced, disease activity is likely to return," the study concludes.

INFORMATION:

(JAMA Neurol. Published online August 31, 2015. doi:10.1001/jamaneurol.2015.1806. Available pre-embargo to the media at http://media.jamanetwork.com.)

Editor's Note: Authors made conflict of interest disclosures and detailed funding/support. Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.

Media Advisory: To contact corresponding author Kerstin Hellwig, M.D., email k.hellwig@klinikum-bochum.de


ELSE PRESS RELEASES FROM THIS DATE:

Epigenomic changes are key to innate immunological memory

2015-08-31
It was long believed that acquired immunity--a type of immunity mediated by T- and B-cells--had memory, meaning that it could learn from new pathogens, making subsequent reactions more effective, whereas innate immunity--which is mediated by macrophages and other types of cells that react to certain molecules typically associated with pathogens--did not. However, it gradually became clear that things were not so simple. Plants and insects, which only have innate immunity, also seem to have immunological memory. Further, it has been reported that herpes virus infection increases ...

'Eat me' signal whets appetites for tumor-devouring dendritic cells

2015-08-31
By changing the mouse model they use to study how the immune system responds to cancer, a team of researchers hopes to shift the focus for one emerging form of cancer immunotherapy back to the standard approach--relying on antigen-presenting dendritic cells--and away from the current upstart, macrophages. Although macrophages, like dendritic cells, also take up antigens, they are more likely to degrade them than present them to T cells. The recent emphasis on macrophages stems, in part, from promising, but problematic, efforts to develop an effective macrophage-driven ...

CNIO scientists propose attacking bioenergetic metabolism to improve anti-cancer therapies

CNIO scientists propose attacking bioenergetic metabolism to improve anti-cancer therapies
2015-08-31
Cancer cells become addicted to glucose, which they use as their regular source of energy to grow and develop. Although this was observed over nine decades ago by the German physiologist, Otto Warburg; there is still not therapeutic strategy today that can effectively take advantage of this special energy requirement. The initial approach appears to be simple: the lack of glucose could specifically induce the death of cancer cells. A new study by the Spanish National Cancer Research Centre Cell and Cancer Unit, headed by the Cell Division and Cancer group of the Spanish ...

DNA-guided 3-D printing of human tissue is unveiled

2015-08-31
A UCSF-led team has developed a technique to build tiny models of human tissues, called organoids, more precisely than ever before using a process that turns human cells into a biological equivalent of LEGO bricks. These mini-tissues in a dish can be used to study how particular structural features of tissue affect normal growth or go awry in cancer. They could be used for therapeutic drug screening and to help teach researchers how to grow whole human organs. The new technique -- called DNA Programmed Assembly of Cells (DPAC) and reported in the journal Nature Methods ...

Closer to a treatment for the 'asthma of the esophagus'

2015-08-31
Scientists from the D'Or Institute of Research and Education (IDOR), the Federal University of Rio de Janeiro (UFRJ) and the Yale University School of Medicine have elucidated the chemical process behind a mysterious gastrointestinal disease that is becoming more frequent every day: the eosinophilic esophagitis (EoE), also known as the "asthma of the esophagus". The researchers identified a molecule which plays a key role in this condition and that can be a target in a new therapeutic strategy. The eosinophilic esophagitis is a chronic inflammatory disorder of the esophagus. ...

The 5-colour nutritional labelling system is the most effective for consumers

2015-08-31
While the French High Council for Public Health (HCSP) made public on Monday, 24 August 2015, a positive opinion regarding the relevance of the 5-colour code for the public, a team of researchers (Inserm/INRA/Paris 13 University) directed by Serge Hercberg, on publication of their article in the journal Nutrients, demonstrated that the 5-colour nutrition label (5-CNL) is the most effective nutritional information system for allowing consumers to recognise and compare the nutritional quality of foods, including "at-risk" populations (older subjects, those with a lower educational ...

Preventive medicine experts speak out about reducing firearm violence

2015-08-31
Amsterdam, NL, August 31, 2015 -- Every week in the U.S. an average of 645 people lose their lives to firearm violence and 1,565 more are treated in an emergency department for a firearm-related injury. Most of these events do not make headlines, but they account for about 7% of the premature deaths before age 65 in the U.S. In a special issue of Preventive Medicine, preventive medicine and health policy experts address a wide range of critical topics related to firearm violence, from the interaction of alcohol abuse with gun violence, effects of changes to gun laws in ...

Alzheimer's disease -- Overlooked for 30 years: A new kid on the block

2015-08-31
Alzheimer's disease is associated with the appearance of characteristic neurotoxic protein aggregates in various regions in the brain. Chemical analysis of these insoluble deposits reveals that they are made up of a family of short protein fragments, referred to as beta-amyloid peptides, which are derived from a precursor protein called APP by the sequential action of two enzymes. An international team of researchers led by Christian Haass (Professor of Metabolic Biochemistry at LMU and Speaker for the German Center for Neurodegenerative Diseases in Munich) and Dr. Michael ...

Mayo researchers examine risk factors/patient outcomes associated with colorectal cancer

2015-08-31
ROCHESTER, Minn. -- About 20 percent of colorectal cancer patients have cancers that have spread (metastasized) beyond the colon at the time of their diagnosis. The liver is the most common site for these metastases. The approach to treating primary tumors within the colon and metastatic tumors in the liver continues to evolve; however, it typically involves chemotherapy plus surgical removal (resection) of both types of tumors. However, experts continue to debate whether surgical resection of primary tumors and metastatic tumors should be performed at the same time (synchronously) ...

As wind-turbine farms expand, research shows they could offer diminishing returns

2015-08-31
LAWRENCE -- Renewable wind energy is experiencing a boom, with more wind turbines popping up across landscapes in the U.S. and abroad. Indeed, wind energy accounted for 3.3 percent of electricity generation in the United States in 2011, according to the U.S. Energy Information Administration. Globally, that number was 2.9 percent for the same year. But as wind turbines proliferate, researchers at the University of Kansas are looking at how these forests of turbines affect the wind itself. What happens to the wind when a larger number of wind turbines removes more and ...

LAST 30 PRESS RELEASES:

How your brain decides blame and punishment -- and how it can be changed

Uniquely human brain region enables punishment decisions

Pinpointing punishment

Chapman University publishes research on attractiveness and mating

E-cigarettes: Special issue from Nicotine & Tobacco Research

Placental problems in early pregnancy associated with 5-fold increased risk of OB & fetal disorders

UT study: Invasive brood parasites a threat to native bird species

Criminals acquire guns through social connections

Restoring ocean health

Report: Cancer remains leading cause of death in US Hispanics

Twin study suggests genetic factors contribute to insomnia in adults

To be fragrant or not: Why do some male hairstreak butterflies lack scent organs?

International team discovers natural defense against HIV

Bolivian biodiversity observatory takes its first steps

Choice of college major influences lifetime earnings more than simply getting a degree

Dominant strain of drug-resistant MRSA decreases in hospitals, but persists in community

Synthetic biology needs robust safety mechanisms before real world application

US defense agencies increase investment in federal synthetic biology research

Robots help to map England's only deep-water Marine Conservation Zone

Mayo researchers identify protein -- may predict who will respond to PD-1 immunotherapy for melanoma

How much water do US fracking operations really use?

New approach to mammograms could improve reliability

The influence of citizen science grows despite some resistance

Unlocking secrets of how fossils form

What happens on the molecular level when smog gets into the lungs?

Using ultrasound to clean medical instruments

Platinum and iron oxide working together get the job done

Tiny silica particles could be used to repair damaged teeth, research shows

A quantum lab for everyone

No way? Charity's logo may influence perception of food in package

[Press-News.org] Exclusive breastfeeding and the effect on postpartum multiple sclerosis relapses
Press-News.org is a service of DragonFly Company. All Rights Reserved.
Issuers of news releases are solely responsible for the accuracy of their content.