Contact Information:

Media Contact

David Sampson

Twitter: ACSNews

Kredyty mieszkaniowe Kredyty mieszkaniowe

Sprawdź aktualny ranking najlepszych kredytów mieszkaniowych w Polsce - atrakcyjne kredytowanie nieruchomości. - Press Release Distribution
RSS - Press News Release
Add Press Release

Prophylactic surgery nearly doubles in men with breast cancer

( ATLANTA - Sept. 2, 2015 - The number of men with breast cancer who undergo surgery to remove the unaffected breast has risen sharply, according to a new report by American Cancer Society and Dana Farber Cancer Institute researchers. The report, appearing in JAMA Surgery, is the first to identify the trend, which mirrors a trend seen in U.S. women over the past two decades.

Breast cancer in men is rare, accounting for only about 1 percent of all cases in the United States. In women (particularly younger women), the use of contralateral prophylactic mastectomy (CPM) surgery to remove the unaffected breast, has increased. The percentage of women with invasive breast cancer in one breast undergoing the surgery increased from about 2.2 % in 1998 to 11% in 2011. This increase has occurred despite the lack of evidence for a survival benefit from treatment, along with associated costs and possible complications.

To explore whether the same increase was occurring among men, researchers led by Ahmedin Jemal, DVM, Ph.D., vice president of surveillance and health services research at the American Cancer Society, looked at treatment among 6332 men who underwent surgery for breast cancer limited to one breast between 2004 and 2011. Researchers pulled nationwide data from the North American Association of Central Cancer Registries (NAACCR) for the study.

The researchers found the rates of CPM among men nearly doubled between 2004 and 2011, from 3.0% to 5.6% (a relative increase of 86.7%). The procedure was more common in younger, white, and privately insured patients. The authors found the same sociodemographic factors linked to more surgery in women (being white, younger age, and having private insurance) are also associated with the use of CPM in men with breast cancer. However, the study did not have data to examine whether the surgery in men is associated with genetic testing, family history, magnetic resonance imaging, or fear of contralateral breast cancer, all of which have been linked to the surgery in women.

"The increase in the rate of this costly, serious procedure with no evidence of survival benefit comes, paradoxically, at a time of greater emphasis on quality and value in cancer care," said Dr. Jemal. "Health care providers should be aware that the increase we've seen in removal of the unaffected breast is not limited to women, and doctors should carefully discuss with their male patients the benefits, harms, and costs of this surgery to help patients make informed decisions about their treatments."


Article: Temporal Trends in and Factors Associated With Contralateral Prophylactic Mastectomy among US Men with Breast Cancer Published Online Sept 2, 2015. Doi10:1001/jamasurg2015.2015.2657

Other authors were: Chun Chieh Lin, PhD, Carol DeSantis, MPH, Helmneh Sineshaw, MD, MPH, of the American Cancer Society and Rachel A. Freedman, MD, MPH, Dana-Farber Cancer Institute


Tracking down the causes of Alzheimer's

Tracking down the causes of Alzheimers
Genes are not only important for regular memory performance, but also for the development of Alzheimer's disease. Researchers at the University of Basel now identified a specific group of genes that plays a central role in both processes. This group of molecules controls the concentration of calcium ions inside the cell. Their results appear in the current issue of the journal JAMA Psychiatry. Intact memory capacity is crucial for everyday life. This fact becomes apparent once a memory disorder has developed. Alzheimer's disease is the most common cause of age-associated ...

Study shows how fracking documentary influenced public perception and political change

WASHINGTON, DC, September 2, 2015 -- Social scientists have long argued documentary films are powerful tools for social change. But a University of Iowa (UI) sociologist and his co-researchers are the first to use the Internet and social media to systematically show how a documentary film reshaped public perception and ultimately led to municipal bans on hydraulic fracking. By measuring an uptick in online searches as well as social media chatter and mass media coverage, Ion Bogdan Vasi, an associate professor of sociology at the UI and corresponding author of a new ...

Exposure to phthalates could be linked to pregnancy loss

A new study of more than 300 women suggests that exposure to certain phthalates -- substances commonly used in food packaging, personal-care and other everyday products -- could be associated with miscarriage, mostly between 5 and 13 weeks of pregnancy. The research, appearing in the ACS journal Environmental Science & Technology, is the first epidemiological study on non-work-related exposure to phthalates to provide evidence for the possible link among a general population. Out of concern over the potential health effects of phthalates, the U.S. has banned six of these ...

New research discovers immune system protein can fix cystic fibrosis cells

Scientific experiments examining what happens to the faulty channel protein that causes cystic fibrosis during inflammation have yielded unexpected and exciting results. The study, conducted by Sara Bitam and her colleagues at INSERM in France, has just passed peer review on open science publishing platform F1000Research. Cystic fibrosis is a life-limiting auto¬somal recessive monogenic disorder that affects 1 in every 2000 - 3500 newborns in the EU and US per year. It is caused by mutations in the gene that encodes the CFTR protein, an epithelial ion channel involved ...

Blueberry extract could help fight gum disease and reduce antibiotic use

Gum disease is a common condition among adults that occurs when bacteria form biofilms or plaques on teeth, and consequently the gums become inflamed. Some severe cases, called periodontitis, call for antibiotics. But now scientists have discovered that wild blueberry extract could help prevent dental plaque formation. Their report in ACS' Journal of Agricultural and Food Chemistry could lead to a new therapy for periodontitis and a reduced need for antibiotics. Many people have had some degree of gum inflammation, or gingivitis, caused by dental plaque. The gums get ...

Evidence that Earth's first mass extinction was caused by critters not catastrophe

NASHVILLE, Tenn. - In the popular mind, mass extinctions are associated with catastrophic events, like giant meteorite impacts and volcanic super-eruptions. But the world's first known mass extinction, which took place about 540 million years ago, now appears to have had a more subtle cause: evolution itself. "People have been slow to recognize that biological organisms can also drive mass extinction," said Simon Darroch, assistant professor of earth and environmental sciences at Vanderbilt University. "But our comparative study of several communities of Ediacarans, ...

New study reveals how changes in lifestyle are contributing to dramatic rise in obesity

New research from Royal Holloway, University of London has found that changes in lifestyle over the past 30 years have led to a sharp reduction in the strenuousness of daily life, which researchers say may explain why there has been a dramatic rise in obesity. The study, carried out by Dr Melanie Luhrmann from the Department of Economics along with Professor Rachel Griffith and Dr Rodrigo Lluberas, revealed that while obesity rates have almost trebled, surprisingly, our actual calorie intake has fallen by around 20 per cent compared to 30 years ago. The researchers found ...

Silk bio-ink could help advance tissue engineering with 3-D printers

Advances in 3-D printing have led to new ways to make bone and some other relatively simple body parts that can be implanted in patients. But finding an ideal bio-ink has stalled progress toward printing more complex tissues with versatile functions -- tissues that can be loaded with pharmaceuticals, for example. Now scientists, reporting in the journal ACS Biomaterials Science & Engineering, have developed a silk-based ink that could open up new possibilities toward that goal. Most inks currently being developed for 3-D printing are made of thermoplastics, silicones, ...

Struggles ahead in China for chemical and pharmaceutical companies

China's economic downturn plus other factors, including overcapacity and tightening regulations, mean the next two to three years could be challenging for the foreign chemical and pharmaceutical companies located there. To survive in China as it adjusts to a slower pace of growth, businesses will likewise need to adapt, reports Chemical & Engineering News (C&EN), the weekly newsmagazine of the American Chemical Society. Jean-François Tremblay, a senior correspondent at C&EN, notes that owing to reforms initiated in 1978, China has been a profitable place for chemical ...

Study provides insights into the mechanisms of fine-tuning of wheat to diverse environments

Study provides insights into the mechanisms of fine-tuning of wheat to diverse environments
MANHATTAN, Kansas -- A Kansas State University wheat geneticist is part of a breakthrough study that identifies one of the wheat genes that controls response to low temperature exposure, a process called vernalization. Natural variation in vernalization genes defines when the plant begins to flower and is critical for adaptation to different environments. Researchers anticipate this will help wheat breeders design wheat varieties that can adapt and thrive in changing environments around the world. Eduard Akhunov, associate professor in the plant pathology department, ...


How your brain decides blame and punishment -- and how it can be changed

Uniquely human brain region enables punishment decisions

Pinpointing punishment

Chapman University publishes research on attractiveness and mating

E-cigarettes: Special issue from Nicotine & Tobacco Research

Placental problems in early pregnancy associated with 5-fold increased risk of OB & fetal disorders

UT study: Invasive brood parasites a threat to native bird species

Criminals acquire guns through social connections

Restoring ocean health

Report: Cancer remains leading cause of death in US Hispanics

Twin study suggests genetic factors contribute to insomnia in adults

To be fragrant or not: Why do some male hairstreak butterflies lack scent organs?

International team discovers natural defense against HIV

Bolivian biodiversity observatory takes its first steps

Choice of college major influences lifetime earnings more than simply getting a degree

Dominant strain of drug-resistant MRSA decreases in hospitals, but persists in community

Synthetic biology needs robust safety mechanisms before real world application

US defense agencies increase investment in federal synthetic biology research

Robots help to map England's only deep-water Marine Conservation Zone

Mayo researchers identify protein -- may predict who will respond to PD-1 immunotherapy for melanoma

How much water do US fracking operations really use?

New approach to mammograms could improve reliability

The influence of citizen science grows despite some resistance

Unlocking secrets of how fossils form

What happens on the molecular level when smog gets into the lungs?

Using ultrasound to clean medical instruments

Platinum and iron oxide working together get the job done

Tiny silica particles could be used to repair damaged teeth, research shows

A quantum lab for everyone

No way? Charity's logo may influence perception of food in package

[] Prophylactic surgery nearly doubles in men with breast cancer is a service of DragonFly Company. All Rights Reserved.
Issuers of news releases are solely responsible for the accuracy of their content.