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Outcomes after stem cell transplant in elderly patients with acute myeloid leukemia have improved since 2000

2024-03-22
Bottom Line: Among patients over 65 who received an allogeneic hematopoietic stem cell transplant (allo-HCT) for the treatment of acute myeloid leukemia (AML) between 2000 and 2021, leukemia-free and overall survival improved significantly over time. Journal in Which the Study was Published: Clinical Cancer Research, a journal of the American Association for Cancer Research (AACR) Author: Ali Bazarbachi, MD, PhD, senior author of the study and a professor at the American University of Beirut in Lebanon Background: AML ...

Longer genes are linked to aging

2024-03-22
  · Long genes have more potential sites for DNA damage · Genes involved in brain loss during aging and linked to Alzheimer’s are very long · New view of biological aging differs from previous beliefs CHICAGO --- What causes our body to age? Four complementary studies, including one from Northwestern Medicine, have come to the same conclusion: long genes.  In a new paper, the scientists write about their findings and how they advance existing knowledge about aging.  “Long genes ...

Revolutionizing hydrogen production: Economical and efficient solutions unveiled

Revolutionizing hydrogen production: Economical and efficient solutions unveiled
2024-03-22
Water eletrolysis process is a system that produces hydrogen by electrolyzing water. It is an eco-friendly technology that can produce hydrogen fuel, a future energy source, without emitting environmental pollutants, but its limitations have been pointed out as low hydrogen production efficiency and high production costs. Recently, a team of researchers from Pohang University of Science and Technology (POSTECH) published research that solved both problems at once, attracting attention.   A collaborative research team comprising Professor Jong Kyu Kim, Jaerim Kim, a Ph. D. candidate, Professor ...

James Webb Space Telescope captures the end of planet formation

James Webb Space Telescope captures the end of planet formation
2024-03-22
Scientists believe that planetary systems like our solar system contain more rocky objects than gas-rich ones. Around our sun, these include the inner planets – Mercury, Venus, Earth and Mars –  the asteroid belt and the Kuiper belt objects such as Pluto. Jupiter, Saturn, Uranus and Neptune, on the other hand, contain mostly gas. But scientists also have known for a long time that planet-forming disks start out with 100 times more mass in gas than solids, which leads to a pressing question: When ...

If faces look like demons, you could have this extraordinary condition

If faces look like demons, you could have this extraordinary condition
2024-03-22
Imagine if every time you saw a face, it appeared distorted. Well, for those who have a very rare condition known as prosopometamorphopsia (PMO), which causes facial features to appear distorted, that is reality. As the Dartmouth-based website about prosopometamorphopsia explains, "'Prosopo' comes from the Greek word for face 'prosopon' while 'metamorphopsia' refers to perceptual distortions.''' Specific symptoms vary from case to case and can affect the shape, size, color, and position ...

Birmingham scientists win funding to develop “lollipops” for mouth cancer diagnosis

2024-03-22
VIDEO available to download HERE of scientist Ruchi Gupta explaining how she hopes to make a lollipop or lozenge to diagnose mouth cancer. The film features mouth cancer survivor Rachel Parsons and contains explicit images. A ‘LOLLIPOP’ that can diagnose mouth cancer early could become a reality, thanks to a pioneering project funded by Cancer Research UK and the Engineering and Physical Sciences Research Council (EPSRC). Dr Ruchi Gupta at the University of Birmingham has been awarded £350,000 over the next three years by Cancer Research UK and EPSRC to make a prototype flavoured ‘lollipop’ from a material called a smart hydrogel. Smart ...

Reviving England’s polluted rivers? Incentivising farmers and comprehensive monitoring among key recommendations from experts

Reviving England’s polluted rivers? Incentivising farmers and comprehensive monitoring among key recommendations from experts
2024-03-22
At the close of 2023, Defra asked the British Ecological Society to bring together nearly 40 experts, to collate expert opinion on freshwater policy and set out a list of priorities for the biodiversity evidence programme to focus on. Published today, the new report sets out priorities for restoring England’s polluted fresh waters.  We know that England’s rivers, and the life they support, are in a desperate state. The River Trust’s annual State of Our Rivers report found that a mere 15% of rivers in England were classed as being in good ecological health and no ...

NASA’s tiny BurstCube mission launches to study cosmic blasts

NASA’s tiny BurstCube mission launches to study cosmic blasts
2024-03-22
NASA’s BurstCube, a shoebox-sized satellite designed to study the universe’s most powerful explosions, is on its way to the International Space Station. The spacecraft travels aboard SpaceX’s 30th Commercial Resupply Services mission, which lifted off at 4:55 p.m. EDT on Thursday, March 21, from Launch Complex 40 at Cape Canaveral Space Force Station in Florida. After arriving at the station, BurstCube will be unpacked and later released into orbit, where it will detect, locate, and study short gamma-ray ...

Research reveals link between menstrual cycles, emotions, and sleep patterns in women

2024-03-22
Women experience disruptions in their sleep patterns and report heightened feelings of anger in the days leading up to their period, according to new research.  The study sheds new light on the intricate relationship between women's menstrual cycles, emotions, and sleep patterns.   Co-author Dr Jo Bower, of the University of East Anglia’s School of Psychology, said: “Our research provides valuable insights into the complex interplay between menstrual cycles, emotions, ...

Breast cancer patients can safely avoid extensive removal of lymph nodes if they respond well to primary systemic treatment

Breast cancer patients can safely avoid extensive removal of lymph nodes if they respond well to primary systemic treatment
2024-03-22
Milan, Italy: Patients with breast cancer that has started to spread to the lymph nodes in the armpit can safely avoid extensive removal of the lymph nodes if their treatment is tailored to their response to cancer-killing therapies such as chemotherapy before surgery.   In a presentation to the 14th European Breast Cancer Conference today (Friday) in Milan, Annemiek Van Hemert, a doctor and PhD student in the Surgical Oncology Department of Antoni van Leeuwenhoek-Netherlands Cancer Institute (AVL-NKI) in Amsterdam (The Netherlands), said: “If we are able to predict the response based on the removal of ...

Replacing sugar with sweeteners can improve weight loss control over the long-term in adults in the overweight range, finds European randomised controlled trial

2024-03-21
*This is an early press release from the European Congress on Obesity (ECO 2024) Venice 12-15 May. Please credit the Congress if using this material* New research being presented at this year’s European Congress on Obesity (ECO) in Venice, Italy (12-15 May), suggests that replacing sugar-sweetened food and drinks with low/no energy sweetened products can help weight control for at least one year after rapid weight loss in adults, without increasing the risk of type 2 diabetes or cardiovascular disease. The findings of a year-long randomised controlled trial involving adults with overweight and obesity and children in the overweight range from Northern, Central and ...

Early registration opens for 2024 International Space Station Research and Development Conference in Boston

2024-03-21
BOSTON (MA), March 21, 2024 – This July, the 13th annual International Space Station Research and Development Conference (ISSRDC) returns to Boston, where leaders from the commercial sector, U.S. government agencies, and academic communities will assemble to highlight innovations and opportunities through our nation’s orbiting outpost. ISSRDC will take place July 30-August 1, 2024, at the Marriott Copley Place in Boston. Early registration is now open until May 24, 2024. Booking during early ...

Marine Biological Laboratory announces 2024 Logan Science Journalism Fellows

Marine Biological Laboratory announces 2024 Logan Science Journalism Fellows
2024-03-21
WOODS HOLE, Mass. –Twelve accomplished science and health journalists have been awarded a highly competitive fellowship in the Logan Science Journalism Program at the Marine Biological Laboratory (MBL). Now in its 37th year, the Logan Science Journalism Program provides journalists with immersive, hands-on research training, giving them invaluable insight into the practice of science as well as some of the major news stories of today. The program, which offers a Biomedical course and an Environmental course, will run May 13-23 in Woods Hole. Biographies for the 2024 Logan Science Journalism Fellows are here. They are: Biomedical Fellows Pakinam Amer, Independent ...

Novel imaging platform allows researchers to study placental development in pregnant mice

Novel imaging platform allows researchers to study placental development in pregnant mice
2024-03-21
DURHAM, N.C. -- Physicians and biomedical engineers at Duke University have developed a method to visualize the growth of a placenta throughout a mouse’s pregnancy. By coupling an implantable window with ultrafast imaging tools, the approach provides the first opportunity to track placental development to better understand how the organ functions during pregnancy. This new perspective gives researchers a precise way to examine how lifestyle factors like alcohol consumption and health complications like inflammation can affect the placenta and potentially lead to adverse pregnancy outcomes. The research appears March 20 as the cover ...

AMS Science Preview: “Outdoor days,” lightning, air pollution

2024-03-21
The American Meteorological Society continuously publishes research on climate, weather, and water in its 12 journals. Many of these articles are available for early online access–they are peer-reviewed, but not yet in their final published form. Below is a selection of articles published early online recently. To view full article text, members of the media can contact kpflaumer@ametsoc.org for press login credentials. Observed Changes in Extreme Precipitation Associated with United States Tropical Cyclones Journal of Climate Rainfall ...

Illinois study: Systematic review of agricultural injuries can help inform safety measures

Illinois study: Systematic review of agricultural injuries can help inform safety measures
2024-03-21
URBANA, Ill. – Agricultural occupations are  hazardous with one of the highest rates of workplace injuries and fatalities in the U.S. The manual and often strenuous nature of the work, combined with the use of machinery and exposure to environmental hazards create a challenging work environment. Understanding the nature and causes of injuries can help improve safety guidelines and policy measures. However, obtaining a comprehensive overview of injuries is hindered by the absence of a central reporting system. Two ...

New vaccine against a highly fatal tropical disease – and potential bioterror weapon – demonstrates efficacy in animal studies

New vaccine against a highly fatal tropical disease – and potential bioterror weapon – demonstrates efficacy in animal studies
2024-03-21
In a mouse study, UCLA researchers tested a vaccine against the bacterium that causes melioidosis and found it was highly protective against the disease, which is endemic in many tropical areas, causing approximately 165,000 cases with 89,000 fatalities around the world each year.  The bacterium, called Burkholderia pseudomallei, is spread through contact with contaminated soil and water through inhalation, ingestion or broken skin. It is so dangerous that it is categorized as a Tier 1 Select Agent of bioterrorism, and it can cause ...

Artificial intelligence helps explore chemistry frontiers

Artificial intelligence helps explore chemistry frontiers
2024-03-21
The ability to simulate the behavior of systems at the atomic level represents a powerful tool for everything from drug design to materials discovery. A team led by Los Alamos National Laboratory researchers has developed machine learning interatomic potentials that predict molecular energies and forces acting on atoms, enabling simulations that save time and expense compared with existing computational methods. “Machine learning potentials increasingly offer an effective alternative to computationally ...

UMass Amherst engineers create bioelectronic mesh capable of growing with cardiac tissues for comprehensive heart monitoring

UMass Amherst engineers create bioelectronic mesh capable of growing with cardiac tissues for comprehensive heart monitoring
2024-03-21
AMHERST, Mass. – A team of engineers led by the University of Massachusetts Amherst and including colleagues from the Massachusetts Institute of Technology (MIT) recently announced in the journal Nature Communications that they had successfully built a tissue-like bioelectronic mesh system integrated with an array of atom-thin graphene sensors that can simultaneously measure both the electrical signal and the physical movement of cells in lab-grown human cardiac tissue. In a research first, this tissue-like mesh can grow along with the cardiac cells, ...

Researchers take major step toward developing next-generation solar cells

2024-03-21
The solar energy world is ready for a revolution. Scientists are racing to develop a new type of solar cell using materials that can convert electricity more efficiently than today’s panels.  In a new paper published February 26 in the journal Nature Energy, a University of Colorado Boulder researcher and his international collaborators unveiled an innovative method to manufacture the new solar cells, known as perovskite cells, an achievement critical for the commercialization of what ...

CUNY ISPH to launch next phase of community-based cohort study to track short- and long-term effects of multiple respiratory viruses

2024-03-21
The City University of New York (CUNY) Institute for Implementation Science in Population Health (ISPH) and the CUNY Graduate School of Public Health and Health Policy (CUNY SPH), in collaboration with Pfizer, are initiating a critical two-year prospective epidemiologic study in the spring of 2024 to track acute respiratory infections across the United States. Project PROTECTS (Prospective Respiratory Outcomes from Tracking and Evaluating Community-based TeSting) builds on the CHASING COVID Cohort Study, which has monitored SARS-CoV-2 infection rates and ...

47th Annual UNC Lineberger Scientific Symposium: “Pancreatic Cancer: From Discovery to the Clinic”

47th Annual UNC Lineberger Scientific Symposium: “Pancreatic Cancer: From Discovery to the Clinic”
2024-03-21
UNC Lineberger Comprehensive Cancer Center is hosting its 47th annual scientific symposium, “Pancreatic Cancer: From Discovery to the Clinic,” on May 21-22 at the Friday Center for Continuing Education in Chapel Hill, North Carolina. The symposium is free and will feature 15 talks on the latest in pancreatic cancer basic, translational and clinical research by faculty at the University of North Carolina, Dana-Farber Cancer Institute, Johns Hopkins Sidney Kimmel Cancer Center, Memorial Sloan Kettering Cancer Center, University of Michigan ...

A new path to drug diversity

A new path to drug diversity
2024-03-21
Many important medicines, such as antibiotics and anticancer drugs, are derived from natural products from Bacteria. The enzyme complexes that produce these active ingredients have a modular design that makes them ideal tools for synthetic biology. By exploring protein evolution, a team led by Helge Bode from the Max Planck Institute for Terrestrial Microbiology in Marburg, Germany, has found new "fusion sites" that enable faster and more targeted drug development. Industry often follows the assembly line principle: components are systematically assembled into complex products, with different production lines yielding different products. However, not humans are the ...

Satellite data assimilation improves forecasts of severe weather

Satellite data assimilation improves forecasts of severe weather
2024-03-21
UNIVERSITY PARK, Pa. — In 2020, a line of severe thunderstorms unleashed powerful winds that caused billions in damages across the Midwest United States. A technique developed by Penn State scientists that incorporates satellite data could improve forecasts — including where the most powerful winds will occur — for similar severe weather events. The researchers reported in the journal Geophysical Research Letters that adding microwave data collected by low-Earth-orbiting satellites to existing computer weather forecast models produced more accurate forecasts of surface gusts in a case study of the 2020 Midwest ...

Morality among low-risk differentiated thyroid cancer survivors in the U.S.

Morality among low-risk differentiated thyroid cancer survivors in the U.S.
2024-03-21
A new study has shown that overall and cause-specific mortality rates in individuals in the U.S. with low-risk differentiated thyroid cancer (DTC) are low. The study is published in the peer-reviewed journal Thyroid®, the official journal of the American Thyroid Association® (ATA®). Click here to read the article now. Cari Kitahara, PhD, from the National Cancer Institute, National Institutes of Health, and coauthors identified 51,854 individuals diagnosed with first primary DTC at low risk ...
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