PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Second ACL injuries 6 times more likely after reconstruction

2013-07-11
(Press-News.org) CHICAGO, IL – Anterior cruciate ligament reconstruction (ACLR) surgery is a common knee injury procedure, but the overall incidence rate of having to go through it again within 24 months is 6 times greater than someone who has never had an ACL tear, according to researchers presenting their work today at the American Orthopaedic Society for Sports Medicine's (AOSSM) Annual Meeting in Chicago, IL.

"In our study, female athletes after ACLR demonstrated more than four times greater rate of injury within 24 months than their healthy counterparts. This data highlights the fact that ACLR patients who return to playing sports are at greater risk for injury and should take appropriate precautions to prevent injury," said lead author, Mark V. Paterno, PhD, PT, SCS, ATC from the Cincinnati Children's Hospital.

Researchers analyzed data from 78 subjects (59 female, 19 male) between 10 and 25 years old, who underwent ACLR and were ready to return to a pivoting/cutting sport (RTS) and 47 healthy, control individuals. Each subject was followed for injury and athletic exposure for a 24-month period after returning to play. Twenty-three of the ACLR individuals and 4 control subjects suffered an ACL injury. Within the ACLR group, there also appeared to be a trend for female subjects to be two times more likely to suffer an injury on the opposite knee than on the previously injured one. Overall, 29.5% of athletes suffered a second ACL injury within 24 months of returning to activity with 20.5% sustaining an opposite leg injury and 9.0% incurring graft re-tear injury on the same leg. A higher proportion of females (23.7%) suffered an opposite leg injury compared to males (10.5%).

"Our study represents the first report of subsequent ACL injury incidence rate focused on 2 -year outcomes of young, active patients returning to sport. Even though additional research still needs to be performed to support our findings, our data does provide early evidence for re-examining current rehabilitation and return to sport protocols following ACLR," said Paterno.

### The American Orthopaedic Society for Sports Medicine (AOSSM) is a world leader in sports medicine education, research, communication and fellowship, and includes national and international orthopaedic sports medicine leaders. The Society works closely with many other sports medicine specialists, including athletic trainers, physical therapists, family physicians, and others to improve the identification, prevention, treatment, and rehabilitation of sports injuries. AOSSM is also a founding partner of the STOP Sports Injuries campaign to prevent overuse and traumatic injuries in kids. For more information on AOSSM or the STOP Sports Injuries campaign, visit http://www.sportsmed.org or http://www.stopsportsinjuries.org


ELSE PRESS RELEASES FROM THIS DATE:

Hippo pathway to better cancer treatment?

2013-07-11
Researchers at the University of British Columbia have discovered a potential new pathway to treat cancer by asking some odd questions about the size of animals. "Mammals display a huge range in size from the largest blue whale to the tiniest fruit bat," says Colby Zaph, assistant professor of Pathology and Laboratory Medicine at the Biomedical Research Centre, who co-authored the study published in Developmental Cell. "So why don't we have miniature whales or gigantic bats? It turns out that there are specific pathways that tell cells when to grow and when to stop." One ...

Killer whale genetics: Redefining stock structure in a marine top predator

2013-07-11
Found in every ocean around the world, killer whales are a force to be reckoned with globally. Their remarkable social bonds and sophisticated hunting techniques make them top predators in their salty domain. For many years, it was assumed that these clever, highly mobile whales bred with each other freely in the seemingly homogeneous ocean. As our understanding of the oceans' complexity has grown, and dedicated researchers have peered ever deeper into the world of killer whales, it has become clear that the truth is far more nuanced. As the agency responsible for conserving ...

Important advance in the fight against skin cancer

2013-07-11
Researchers from the Hospital del Mar Medical Research Institute (IMIM), lead by Lluís Espinosa, have identified a new function of the IB protein that is key in the development of squamous-cell carcinoma, a type of skin cancer. The study has been published in the prestigious journal Cancer Cell and provides a new tool for the diagnosis of the disease and, in the future, will enable the identification of novel therapeutic targets to treat this type of cancer. "In this study we identified a new function of a protein that directly regulates the activity of the genes involved ...

Hubble spots azure blue planet

2013-07-11
Astronomers using the NASA/ESA Hubble Space Telescope have, for the first time, determined the true colour of a planet orbiting another star. If seen up close this planet, known as HD 189733b, would be a deep cobalt blue, reminiscent of Earth's colour as seen from space. But that's where the similarities end. This "deep blue dot" is a huge gas giant orbiting very close to its host star. The planet's atmosphere is scorching with a temperature of over 1000 degrees Celsius, and it rains glass, sideways, in howling 7000 kilometre-per-hour winds [1]. At a distance of 63 ...

Recession led teens to focus more on social problems, environment, psychologists report

2013-07-11
During the Great Recession, high school students in the U.S. became more concerned about others and the environment, psychologists at UCLA and San Diego State University report in a new study. The research, published July 11 in the journal Social Psychological and Personality Science, focused on survey data collected on high school seniors during three time periods: the global recession (2008-10), just before the recession (2004-06) and the earliest period for which data were available (1976-78). The study authors found that high school students' concern for others ...

Critical pathway in cell cycle may lead to cancer development

2013-07-11
LA JOLLA, CA ----A team of scientists at the Salk Institute for Biological Studies has identified why disruption of a vital pathway in cell cycle control leads to the proliferation of cancer cells. Their findings on telomeres, the stretches of DNA at the ends of chromosomes that protect our genetic code and make it possible for cells to divide, suggest a potential target for preventive measures against cancer, aging and other diseases. The findings were published July 11 in Molecular Cell. Telomeres have been compared to the plastic tips at the end of shoelaces because ...

New insight into the human genome through the lens of evolution

2013-07-11
By comparing the human genome to the genomes of 34 other mammals, Australian scientists have described an unexpectedly high proportion of functional elements conserved through evolution. Less than 1.5% of the human genome is devoted to conventional genes, that is, encodes for proteins. The rest has been considered to be largely junk. However, while other studies have shown that around 5-8% of the genome is conserved at the level of DNA sequence, indicating that it is functional, the new study shows that in addition much more, possibly up to 30%, is also conserved at ...

New hope in the fight against childhood cancer

2013-07-11
Researchers in the Antibody and Vaccine Group have developed two monoclonal antibodies (mAbs) called anti-4-1BB and anti-CD40 and investigated a third called anti-CTLA-4. Each of these antibodies binds to a different target molecule in the immune system, potentially heightening the body's own immune response to cancer. Published in the July edition of Clinical Cancer Research, the study has shown that the antibodies boost the immune system to fight neuroblastoma -- a form of childhood cancer which grows from undeveloped tissue of the nervous system. They found that ...

Preventing cell death in osteoarthritis

2013-07-11
UK scientists have found a naturally occurring molecule in the body which may have important consequences for treating osteoarthritis. Researchers from The University of Manchester and the University of Westminster have found that the molecule, known as Urocortin, protects cells in the joints from being destroyed. The discovery could help lead to the development of new medicines to prevent joint degradation -- a condition which affects millions of people in the UK each year. Osteoarthritis, a painful condition associated with a loss of joint mobility particularly in ...

Elephants depend on water for cooling, but only when it gets too hot

2013-07-11
During the hot summer months, there's nothing quite like a nice refreshing and cooling dip in a pool, and it would seem that elephants agree. In fact, in some game parks, elephants will rarely stray far from water, and have even been, albeit controversially, called a water-dependent species. But are they really water dependent and if so what drives this dependence? Is it caused by a necessity to cool down? Robin Dunkin, a researcher from University of California, Santa Cruz, USA explains that although elephants have numerous tricks they use to keep cool, such as using their ...

LAST 30 PRESS RELEASES:

Post-LLM era: New horizons for AI with knowledge, collaboration, and co-evolution

“Sloshing” from celestial collisions solves mystery of how galactic clusters stay hot

Children poisoned by the synthetic opioid, fentanyl, has risen in the U.S. – eight years of national data shows

USC researchers observe mice may have a form of first aid

VUMC to develop AI technology for therapeutic antibody discovery

Unlocking the hidden proteome: The role of coding circular RNA in cancer

Advancing lung cancer treatment: Understanding the differences between LUAD and LUSC

Study reveals widening heart disease disparities in the US

The role of ubiquitination in cancer stem cell regulation

New insights into LSD1: a key regulator in disease pathogenesis

Vanderbilt lung transplant establishes new record

Revolutionizing cancer treatment: targeting EZH2 for a new era of precision medicine

Metasurface technology offers a compact way to generate multiphoton entanglement

Effort seeks to increase cancer-gene testing in primary care

Acoustofluidics-based method facilitates intracellular nanoparticle delivery

Sulfur bacteria team up to break down organic substances in the seabed

Stretching spider silk makes it stronger

Earth's orbital rhythms link timing of giant eruptions and climate change

Ammonia build-up kills liver cells but can be prevented using existing drug

New technical guidelines pave the way for widespread adoption of methane-reducing feed additives in dairy and livestock

Eradivir announces Phase 2 human challenge study of EV25 in healthy adults infected with influenza

New study finds that tooth size in Otaria byronia reflects historical shifts in population abundance

nTIDE March 2025 Jobs Report: Employment rate for people with disabilities holds steady at new plateau, despite February dip

Breakthrough cardiac regeneration research offers hope for the treatment of ischemic heart failure

Fluoride in drinking water is associated with impaired childhood cognition

New composite structure boosts polypropylene’s low-temperature toughness

While most Americans strongly support civics education in schools, partisan divide on DEI policies and free speech on college campuses remains

Revolutionizing surface science: Visualization of local dielectric properties of surfaces

LearningEMS: A new framework for electric vehicle energy management

Nearly half of popular tropical plant group related to birds-of-paradise and bananas are threatened with extinction

[Press-News.org] Second ACL injuries 6 times more likely after reconstruction