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In ancient stellar nurseries, some stars are born of fluffy clouds

In ancient stellar nurseries, some stars are born of fluffy clouds
2025-02-20
Fukuoka, Japan—How are stars born, and has it always been this way? Stars form in regions of space known as stellar nurseries, where high concentrations of gas and dust coalesce to form a baby star. Also called molecular clouds, these regions of space can be massive, spanning hundreds of light-years and forming thousands of stars. And while we know much about the life cycle of a star thanks to advances in technology and observational tools, precise details remain obscure. For example, did stars form this way in the early universe? Publishing in The Astrophysical Journal, researchers from Kyushu University, in collaboration with Osaka Metropolitan ...

Blood pressure drug could be a safer alternative for treating ADHD symptoms, finds study

2025-02-20
Blood pressure drug could be a safer alternative for treating ADHD symptoms, finds study    Repurposing amlodipine, a commonly used blood pressure medicine, could help manage attention-deficit/ hyperactivity disorder (ADHD) symptoms, according to an international study involving the University of Surrey.    In a study published in Neuropsychopharmacology, researchers tested five potential drugs in rats bred to exhibit ADHD-like symptoms. Among them, only amlodipine, a common blood pressure medication, significantly reduced hyperactivity.    To ...

Daily cannabis use linked to public health burden

2025-02-20
WASHINGTON (Feb. 20, 2025)--A new study analyzes the disease burden and the risk factors for severity among people who suffer from a condition called cannabinoid hyperemesis syndrome. Researchers at the George Washington University say the condition occurs in people who are long-term regular consumers of cannabis and causes nausea, uncontrollable vomiting and excruciating pain in a cyclical pattern that often leads to repeated trips to the hospital.   “This is one of the first large studies to examine the burden of disease associated with this cannabis-linked syndrome,” says Andrew Meltzer, professor of emergency medicine ...

A new gene identified in the search for a therapy to treat malignant cardiac arrythmia

2025-02-20
Cardiac arrhythmias affect millions across the world and are responsible for a fifth of all deaths in the Netherlands. Currently there are multiple treatment options, ranging from life-long medication to invasive surgical procedures. Research from Amsterdam UMC and Johns Hopkins University, published today in the European Heart Journal, sets another important step in the hunt for a one-off gene therapy that could improve heart function and protect against arrhythmias. "Arrhythmias often occur due to slowing of conduction of the electrical impulse through the heart. Rapid impulse conduction is needed for ...

‘Fog harvesting’ could yield water for drinking and agriculture in the world’s driest regions

‘Fog harvesting’ could yield water for drinking and agriculture in the world’s driest regions
2025-02-20
With less annual rainfall than 1 mm per year, Chile’s Atacama Desert is one of the driest places in the world. The main water source of cities in the region are underground rock layers that contain water-filled pore spaces which last recharged between 17,000 and 10,000 years ago. Now, local researchers have assessed if ‘fog harvesting,’ a method where fog water is collected and saved, is a feasible way to provide the residents of informal settlements with much needed water. “This research represents a notable shift in the ...

Unveiling the intricate mechanisms behind oxysterol-induced cell death

Unveiling the intricate mechanisms behind oxysterol-induced cell death
2025-02-20
Oxysterols are a class of molecules derived from cholesterol via oxidation or as byproducts of cholesterol synthesis. Despite their relatively low concentration within our bodies, oxysterols are known to play many important biological roles, acting as transcriptional regulators, precursors for bile acid, and key players in brain development. On the flip side, some pathologies are associated with imbalances in oxysterols. In particular, 25-hydroxycholesterol (25-OHC) has been shown to contribute to arteriosclerosis, cancer development, central nervous system ...

Closing the recycle loop: Waste-derived nutrients in liquid fertilizer

Closing the recycle loop: Waste-derived nutrients in liquid fertilizer
2025-02-20
Growing plants can be a joyous, yet frustrating process as plants require a delicate balance of nutrients, sun, and water to be productive.  Phosphorus and nitrogen, which are essential for plant growth, are often supplemented by chemical fertilizers to assure proper balance and output of produce. However, the amount of these nutrients on the planet is increasing due to excessive use, which in turn is causing various environmental problems. For this reason, there is a growing movement to promote sustainable agriculture through the recycling of phosphorus and nitrogen. In Japan, a target has been ...

vmTracking enables highly accurate multi-animal pose tracking in crowded environments

vmTracking enables highly accurate multi-animal pose tracking in crowded environments
2025-02-20
Studying the social behavior of animals in their natural environments is necessary for advancing our understanding of neurological processes. To achieve this, tracking multiple individuals simultaneously and accurately as they interact in shared spaces is crucial. Traditional multi-animal tracking systems, such as multi-animal DeepLabCut (maDLC) and Social LEAP Estimates Animal Poses (SLEAP), use frame-by-frame identification to predict movements without the need for markers. While these tools effectively track poses, such as head direction, in simple scenarios, ...

A special collection to highlight recent advances in air pollution complex research in China

A special collection to highlight recent advances in air pollution complex research in China
2025-02-20
Air pollution is a global environmental problem with serious impacts on human health, climate change, and ecological systems. In China, rapid development in the last several decades has led to a drastic increase in coal consumption and the number of vehicles. As a result, air pollution in China is complicated by the coexistence of high concentrations of primary and secondary trace gases and aerosol particles from multiple sources.   Air pollution complex is a term used to characterize the formation mechanisms of air pollution, and was first proposed by Professor Xiaoyan Tang in 1997. A better understanding of these complex mechanisms is critical for meeting the urgent societal ...

Macrophages express high level of Spp1, linking the environmental particle pollution exposure and the development of emphysema - an important finding for COPD

Macrophages express high level of Spp1, linking the environmental particle pollution exposure and the development of emphysema - an important finding for COPD
2025-02-20
This study is led by Dr. Lianyong Han and Dr. Tobias Stoeger in Germany (Institute of Lung Health and Immunity (LHI), Comprehensive Pneumology Center (CPC), Helmholtz Zentrum München, German Research Center for Environmental Health). By analyzing multiple emphysema and COPD patient datasets, SPP1 is significantly upregulated in the lungs of patients, compared to healthy individuals. “These findings pointed out the clinical relevance of SPP1 induction during COPD development and has motivated us to understand their contributions ...

Fitness apps fuelling disordered eating

Fitness apps fuelling disordered eating
2025-02-20
With New Year resolutions in full swing and health tracking apps at our fingertips, new research reveals concerning links between health and fitness apps and disordered eating, body image concerns and excessive exercise. “Diet and fitness apps are marketed as tools to improve health, however they may also have unintended negative consequences, such as creating pressure to meet goals, concerns about body image as well as provoking feelings of guilt if goals aren’t achieved,” says Ms Isabella Anderberg in the College of Education, Psychology and Social Work. “Whilst there is evidence that these tools can be effective in increasing physical activity, we’re ...

Duke-NUS study targets proteins to reverse lung scarring

2025-02-20
Singapore, 20 February 2025—A discovery at Duke-NUS Medical School offers new hope in the battle against pulmonary fibrosis, a debilitating lung condition that progressively makes it harder for patients to breathe. Scientists have pinpointed proteins in immune cells that, when blocked, could significantly reduce lung tissue scarring. Current treatments primarily manage symptoms and improving quality of life, without addressing the underlying cause of pulmonary fibrosis. Although macrophages, a type of immune cell, had previously been known to contribute to inflammation ...

New toolkit empowers healthcare providers with evidence-based strategies for childhood obesity prevention and treatment

New toolkit empowers healthcare providers with evidence-based strategies for childhood obesity prevention and treatment
2025-02-20
Greaux Healthy—a public service initiative powered by Pennington Biomedical Research Center, in partnership with the State of Louisiana—is proud to announce the release of the Childhood Obesity Prevention, Evaluation and Treatment Toolkit, a comprehensive resource designed to equip healthcare providers with practical, evidence-based guidance for preventing, evaluating, and treating childhood obesity and its related comorbidities. Developed in alignment with the 2023 American Academy of Pediatrics (AAP) clinical practice guidelines, the toolkit synthesizes the latest scientific evidence and ...

UT MD Anderson and Texas Children’s Hospital announce joint venture to end childhood cancer

2025-02-20
HOUSTON ― The University of Texas MD Anderson Cancer Center and Texas Children’s Hospital have announced a transformational collaboration dedicated solely to pediatric cancer care. Approved by the UT System Board of Regents and the Texas Children’s Board of Trustees, this new, first-of-its-kind joint venture will unite the nation’s largest comprehensive pediatric system and a top pediatric cancer program with the nation’s leading comprehensive cancer center. The collaboration has a single ...

Texas Children’s Hospital and UT MD Anderson announce joint venture to end childhood cancer

2025-02-20
HOUSTON, TX (February 19, 2025) – Texas Children’s Hospital and The University of Texas MD Anderson Cancer Center have announced a transformational collaboration dedicated solely to pediatric cancer care. Approved by the Texas Children’s Board of Trustees and the UT System Board of Regents, this new, first-of-its-kind joint venture will unite the nation’s largest comprehensive pediatric system and a top pediatric cancer program with the nation’s leading comprehensive cancer center. The collaboration has a single mission: to end childhood cancer. “The scope and scale of our combined effort will build the world’s preeminent pediatric cancer ...

New medication sinus thrombosis just as safe but more patient-friendly

2025-02-20
Patients affected by sinus thrombosis are treated with blood thinners. Traditionally, these patients are prescribed vitamin K antagonists (VKAs). In order to give the correct dosage, regular check-ups at the thrombosis service are necessary. A global study, coordinated by Amsterdam UMC, now shows that new medication, direct oral anticoagulants (DOACs), are equally safe and effective. The study was published today in The Lancet Neurology.  A big advantage is that this medication is more user-friendly because regular thrombosis monitoring is no longer ...

About 740,000 global deaths from suicide occur annually--that's one death every 43 seconds

2025-02-20
Every minute, four males and six females need inpatient treatment due to suicide attempts around the world. Males die from suicide at twice the rate of females, and their attempts result in death three times more often than female attempts. Globally, 10% of suicides by males and 3% by females were with guns. In the U.S., 55% by males and 31% by females were with guns. Between 1990 and 2021, the global age-standardized death rate for suicide declined by almost 40%, indicating that intervention and prevention are ...

Experts strongly recommend against spine injections for chronic back pain

2025-02-20
Spine injections should not be given to adults with chronic back pain because they provide little or no pain relief compared with sham injections, say a panel of international experts in The BMJ today. Their strong recommendations apply to procedures such as epidural steroid injections and nerve blocks for people living with chronic back pain (lasting at least 3 months) that is not associated with cancer, infection or inflammatory arthritis. Their advice is based on the latest evidence and is part of The BMJ’s ‘Rapid ...

Racism in medicine - are things getting better?

2025-02-20
Five years on since The BMJ’s special issue on racism in medicine, and a global pandemic, the landscape is very different, but has racism in the NHS and UK medicine got better or worse? In 2020, a BMJ investigation found that UK medical schools were failing to deal with complaints of racism. Another round of requests to the UK’s 46 medical schools has now found that eight in 10 (34 of 41 that responded) are collecting data on complaints about racism, up from half in 2020. And the number ...

Forcing UK creatives to ‘opt out’ of AI training risks stifling new talent

2025-02-20
The UK government should resist allowing AI companies to scrape all copyrighted works unless the holder has actively “opted out”, as it puts an unfair burden on up-and-coming creative talents who lack the skills and resources to meet legal requirements. This is according to a new report from University of Cambridge experts in economics, policy and machine learning, who also argue the UK government should clearly state that only a human author can hold copyright – even when AI has been heavily involved. A collaboration between three Cambridge initiatives – ...

Almost 90% of people would agree to genetic testing to tailor medication use, survey finds

2025-02-20
New research shows almost 90% of people in England would agree to genetic testing to get the most effective medication and reduce the risk of side effects 85% thought that the NHS should offer pharmacogenomic testing to people with multiple health conditions 58% of people thought that the NHS should offer this testing to everyone 91% wanted access to their own pharmacogenomic data, with many wanting this via the NHS app Pharmacogenomics – an individual’s genetic response to medications – is an increasingly important strand of personalised healthcare but little is known about the public's views ...

Study: UTA research drives widespread economic impact

Study: UTA research drives widespread economic impact
2025-02-19
University of Texas at Arlington research projects contributed $59 million to the national economy in 2024—an increase of 39% from 2023, according to a new report from the Institute for Research on Innovation and Science (IRIS). UTA has invested heavily in research infrastructure, purchasing cutting-edge scientific equipment and technology, such as North Texas’ most advanced gene sequencer and a super-sensitive magnetic resonance imaging machine for the Clinical Imaging Research Center. The funds also support collaboration with other research organizations. UTA worked through 1,144 unique ...

Promising results from first prenatal therapy for spinal muscular atrophy

Promising results from first prenatal therapy for spinal muscular atrophy
2025-02-19
(MEMPHIS, Tenn. – February 19, 2025) Spinal muscular atrophy (SMA) is a progressive neurodegenerative disorder set in motion before birth. Scientists at St. Jude Children’s Research Hospital led the first in uterotreatment of SMA with the orally administered drug risdiplam. More than two years after the child was born, no identifiable features of SMA have been observed. This study demonstrates the feasibility of treating SMA prenatally and supports further investigation into the approach. The findings were published ...

Nitrogen fixation on marine particles is important in the global ocean

Nitrogen fixation on marine particles is important in the global ocean
2025-02-19
How on Earth? It has puzzled scientists for years whether and how bacteria, that live from dissolved organic matter in marine waters, can carry out N2 fixation. It was assumed that the high levels of oxygen combined with the low amount of dissolved organic matter in the marine water column would prevent the anaerobic and energy consuming N2 fixation. Already in the 1980s it was suggested that aggregates, so-called “marine snow particles”, could possibly be suitable sites for N2fixation, ...

FDA approves vimseltinib for tenosynovial giant cell tumor (TGCT)

2025-02-19
The U.S. Food and Drug Administration (FDA) has approved vimseltinib (RomvimzaTM) for adult patients with a rare condition called tenosynovial giant cell tumor (TGCT). TGCT is a tumor of the tissue that lines the joints.  Sarcoma oncologist William Tap, MD, Chief of the Sarcoma Medical Oncology Service at Memorial Sloan Kettering Cancer Center (MSK), led the international phase 3 MOTION trial that resulted in the drug’s approval. Vimseltinib is a type of targeted therapy called a kinase inhibitor and is taken as a pill.  “This approval is an exciting advance for ...
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