The less intensively you manage the soil, the better the soil can function. Such as not ploughing as often or using more grass-clover mixtures as cover crops. These are the conclusions from a research team led by the Netherlands Institute of Ecology (NIOO-KNAW). Surprisingly, it applies to both conventional and organic farming. These important insights for making agriculture more sustainable are published in the scientific journal Science today. ‘It offers clear evidence to help farmers manage soils better.’ Growing food more sustainably: what's the best way to do this? It is ...

WOODS HOLE, Mass. -- The Frontiers Planet Prize, the world’s largest science competition to enhance planetary health by fast-tracking innovative research, has announced National Champions from 19 different countries who now advance to the International competition, which will award three winners $1M each to scale up their research. Suzanne Tank and co-authors from the Arctic Great Rivers Observatory (ArcticGRO), a multinational project founded at the Marine Biological Laboratory (MBL), were recognized for their publication, “Recent trends in the chemistry of major northern rivers signal widespread Arctic change,” published ...

Amyotrophic lateral sclerosis (ALS) is a disease that destroys the nerves necessary for movement. About 30,000 people in the United States are affected, and doctors still don’t know what causes it. To lay the groundwork for better tests, Thomas Jefferson University researchers Phillipe Loher, Eric Londin, PhD, and Isidore Rigoutsos, PhD are taking a computational biology approach to see how ALS affects molecules in the blood. In a study published in Molecular Neurobiology, the team analyzed blood samples from about 300 people with and without ALS. The research focused on small non-coding ...

As the opioid crisis continues, the number of babies born with neonatal opioid withdrawal syndrome (NOWS) – a condition that affects infants whose mothers used opioids during pregnancy – has risen 5-fold over the past 20 years. According to the Centers for Disease Control (CDC), there are 20,000 infants a year in the United States born with signs of NOWS. These infants often require extended hospital stays and, in some cases, treatment with medications like morphine to relieve withdrawal symptoms. A new study from Walter Kraft, MD, an internist and clinical pharmacologist at Thomas Jefferson University, ...

Leadership from the University of Tennessee, Knoxville, Volkswagen Group of America and Oak Ridge National Laboratory celebrated more than a decade of collaboration and the fifth anniversary of the Volkswagen Innovation Hub Knoxville on April 24. Since 2011, UT and Volkswagen have partnered on strategic research projects that have accelerated the discovery and commercialization of new technology, including battery performance, materials science, power electronics and mobility ...

PHILADELPHIA – Even for patients covered by Medicare, annual out-of-pocket costs for lifesaving cancer treatments taken in pill form have often exceeded $10,000—until recently. Thanks to changes in Medicare Part D introduced by the Inflation Reduction Act (IRA) that took effect in 2025, annual out-of-pocket drug costs for all beneficiaries are now capped at $2,000. However, an overlooked voluntary program that’s part of the IRA could be the key to improving affordability for Medicare patients needing expensive oral cancer drugs, according to a new study from researchers ...

Senescent skin cells, often referred to as zombie cells because they have outlived their usefulness without ever quite dying, have existed in the human body as a seeming paradox, causing inflammation and promoting diseases while also helping the immune system to heal wounds.  New findings may explain why: Not all senescent skin cells are the same. Researchers from Johns Hopkins University have identified three subtypes of senescent skin cells with distinct shapes, biomarkers, and functions—an advance that could equip scientists with the ability to target and kill the harmful types while leaving the helpful ones intact.  The findings were published today ...

University of Cincinnati Cancer Center researchers will present abstracts at the American Association for Cancer Research Annual Meeting 2025 in Chicago. Study finds contrasting effects of protein on head and neck cancer A small protein called IL-9 has been shown to either contribute to or counteract tumor growth depending on the type of cancer, but its role in head and neck cancer has not been studied. Abstract lead author Sam Nusbaum and her colleagues found IL-9 levels are increased in patients with head and neck cancer compared to healthy controls.  “High ...

BOSTON, April 25, 2025 – Numerous studies conducted by researchers at Dana-Farber Cancer Institute report progress for cancers including head and neck cancer, metastatic breast cancer and lung cancer. The results of these studies, along with dozens of others led by Dana-Farber faculty, will be presented at this year’s American Association for Cancer Research (AACR) Annual Meeting held April 25-30, 2025, in Chicago. The institute’s leading experts and researchers will present findings across a spectrum of diseases, underscoring ...

ABSTRACTS: CT012, CT132, CT265   CHICAGO, APRIL 25, 2025 ― Researchers from The University of Texas MD Anderson Cancer Center will present promising results from clinical trials in three minisymposia abstracts at the American Association for Cancer Research (AACR) Annual Meeting 2025. Findings include a personalized vaccine combination therapy for colorectal cancer, the use of radiotherapy to avoid the toxicities of systemic treatments for kidney cancer, and engineered exosomes to silence mutant KRAS in pancreatic cancer. In addition to these trials, forthcoming ...

LOS ANGELES — It’s no secret that our waistlines often expand in middle-age, but the problem isn’t strictly cosmetic. Belly fat accelerates aging and slows down metabolism, increasing our risk for developing diabetes, heart problems and other chronic diseases. Exactly how age transforms a six pack into a softer stomach, however, is murky. Now preclinical research by City of Hope®, one of the largest and most advanced cancer research and treatment organizations in the United States and a leading research center for diabetes and other life-threatening illnesses, has uncovered the cellular culprit behind age-related abdominal fat, providing new insights into why ...

Researchers from SYSU and IHEP have developed a unique muon veto detector system for TAO, a satellite experiment of the Jiangmen Underground Neutrino Observatory (JUNO). This system features a top veto tracker system with remarkable characteristics such as high light yield, distinct signal-background differentiation and high detection efficiency even at high thresholds, provides the TAO experiment with a robust capability to suppress cosmic muon induced fast neutron and radioisotope events which are significant correlated backgrounds for the neutrino signal. This scalable solution establishes a transferable ...

Using a 3D printer to create organic tissue models that function like living organs may sound like science fiction — but engineers at the University of Pittsburgh are making it reality.  Central to their breakthrough is a simple yet powerful idea: when provided with the right environment, cells instinctively know how to organize and function. The key lies in designing scaffolds that mimic the body’s natural structures, giving cells the cues they need to grow, interact, and form tissues. Daniel Shiwarski, assistant professor of bioengineering at the Swanson School of Engineering with a joint appointment at the School of Medicine’s Vascular ...

Background and objectives Atypical trigeminal neuralgia (ATN) is a chronic pain condition characterized by persistent facial pain that does not respond well to conventional medical treatments, often leading to significant impairment in quality of life. This study examined the clinical characteristics and surgical outcomes of microvascular decompression combined with nerve combing in patients with ATN. Methods We conducted a retrospective analysis of surgical techniques, clinical data, and treatment outcomes in 40 patients from January 2009 to January 2018. Pain levels ...

Many products in the modern world are in some way fabricated using computer numerical control (CNC) machines, which use computers to automate machine operations in manufacturing. While simple in concept, the ways to instruct these machines is in reality often complex. A team of researchers including those from the University of Tokyo devised a system to demonstrate how to mitigate some of this complexity. Draw2Cut allows users to draw desired designs directly onto material to be cut or milled. In this case, color-coded lines drawn with standard marker pens instruct the Draw2Cut system to mill designs into wood without any prior knowledge of CNC machines or ...

A rare cell type in the lungs is essential to survival from the COVID-19 virus, a new study shows. Experiments in mice infected with the SARS-CoV-2 virus revealed that the immune cell class in question, called nerve and airway-associated interstitial macrophages, or NAMs, may keep the human immune system’s initial counterattack on the virus (lung inflammation) from spiraling out of control to endanger patients. Macrophages are known to be the first responders to infection, as large immune cells capable of devouring invading viruses and the cells they infect. Led by researchers at NYU Langone ...

About The Study: This economic evaluation estimates that expanded Medicare coverage for glucagon-like peptide-1 receptor agonists (GLP-1RAs) would increase access and reduce obesity-related comorbidities but impose substantial costs over 10 years. Even with a moderate scenario (5% uptake, 20% adherence, and 30% additional price discount), net spending was still projected to reach $8 billion over a decade, underscoring the need for further price reductions, lower-cost strategies to prevent weight regain, and reductions in spending ...

About The Study: The findings of these repeated cross-sectional surveys suggest that the difference in cigarette smoking prevalence between historically high vs low prevalence states will shrink by 2035, primarily from much faster declines among young adults in the traditionally highest prevalence states. Slower prevalence declines among older adults are likely to slow the decline in health consequences in these states. Corresponding Author: To contact the corresponding author, John P. Pierce, PhD, email jppierce@health.ucsd.edu. To access the embargoed study: Visit ...

Researchers at University of California San Diego found that cigarette smoking continues to decline across the United States, largely driven by young adults. Their study, published in JAMA Network Open on April 25, 2025, reveals that the states with historically high smoking rates have seen the most dramatic declines. However, smoking cessation progress among adults over 50 has been much slower, which could prolong the public health burden of smoking-related diseases and death. “The rapid decline in smoking among young adults is clear evidence that the smoking epidemic will come to an end in our lifetime,” said Matthew ...

NFCR Congratulates Dr. Robert C. Bast, Jr. on Receiving the AACR-Daniel D. Von Hoff Award for Outstanding Contributions to Education and Training in Cancer Research Rockville, MD — The National Foundation for Cancer Research (NFCR) proudly congratulates Dr. Robert C. Bast, Jr., a pioneering cancer scientist, and NFCR-supported investigator from 2001 to 2018, on being named the 2025 recipient of the AACR-Daniel D. Von Hoff Award for Outstanding Contributions to Education and Training in Cancer Research. Presented by the American Association for Cancer Research (AACR), ...

Understanding how cells differentiate during early embryonic development is crucial for advancing regenerative medicine and developmental biology. Pluripotent stem cells (PSCs) have been invaluable tools in this field, as they can transform into various cell types in the body and play key roles during early embryonic development. Unfortunately, research on this topic in humans and other primates has long been hampered by ethical constraints and technical limitations. Of particular interest are naive-type PSCs, which represent an earlier developmental state than conventional (or ‘primed’) PSCs and possess enhanced differentiation potential. While human naive PSCs can differentiate ...

Researchers have developed a new therapy that can be injected intravenously right after a heart attack to promote healing and prevent heart failure.   The therapy both prompts the immune system to encourage tissue repair and promotes survival of heart muscle cells after a heart attack. Researchers tested the therapy in rats and showed that it is effective up to five weeks after injection.  The research team, led by bioengineers at the University of California San Diego and chemists at Northwestern University, published ...

FlexTech, an international academic journal (ISSN 2771-1706), jointly published by Tsinghua University Press and Wiley Publishing Group, has officially released its first issue. Supported by Tsinghua University’s State Key Laboratory of Flexible Electronics Technology, the journal aims to serve as a global platform for scholars to advance cutting-edge research and engineering applications in flexible materials, devices, and systems, driving humanity toward an intelligent era.   Editor-in-Chief’s Vision: Bridging Humanity, Machines, and the Digital World In his inaugural editorial, Prof. Xue Feng from Tsinghua University, Editor-in-Chief ...

Studies by a growing number of labs have identified neurological health benefits from exposing human volunteers or animal models to light, sound and/or tactile stimulation at the brain’s “gamma” frequency rhythm of 40Hz. In the latest such research at The Picower Institute for Learning and Memory and Alana Down Syndrome Center at MIT, scientists found that 40Hz sensory stimulation improved cognition and circuit connectivity and encouraged the growth of new neurons in mice genetically engineered to model Down syndrome. Li-Huei Tsai, Picower Professor at MIT and senior author of the new study in PLOS ONE, said that the results are encouraging but also cautioned ...

Methyl eugenol (ME), a phenylpropanoid compound found in the essential oils of various aromatic plants, has recently garnered attention due to its significant antioxidant, anticancer, and neuroprotective properties. ME, commonly used in the fragrance and food industries, is also studied for its potential therapeutic effects, particularly in mitigating diseases associated with oxidative stress, such as Alzheimer’s disease, cancers, and ischemic brain injuries. However, despite its therapeutic promise, concerns ...