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Sophisticated neuroimaging reveals PTSD in WTC responders is linked to measurable physical changes in brain structure

2025-12-17
December 17, 2025 – New research among World Trade Center (WTC) responders with chronic post-traumatic stress disorder (PTSD) has uncovered measurable physical changes in their brain structure, consistent with changes in the balance of myelinated to unmyelinated neurons (fast- and slow-conducting nerve cells) across both hemispheres of the brain. These changes were most strongly associated with re-experiencing symptoms in individuals with PTSD. The cortical differences found in this sophisticated imaging study in Biological Psychiatry: Cognitive ...

Health policy experts identify promising strategies for providing health care to homeless people

2025-12-17
Organizations aiming to help homeless people with either housing or health care can be more effective when they form partnerships with other service groups, a Rutgers study has found. “Our paper describes how homeless services and health care providers are working together to tackle the challenge of providing healthcare to the unhoused,” said Joel Cantor, director of the Rutgers Center for State Health Policy, a Distinguished Professor at the Edward J. Bloustein School of Planning and Public Policy and coauthor of the paper published in The Milbank ...

Study explores role of neutrophils in canine atopic dermatitis

2025-12-17
A new study from North Carolina State University found that neutrophils – white blood cells that are a key part of the immune system – play a role in the early stages of atopic dermatitis flares in dogs. The work is a first step toward understanding the role that these immune cells may play in the early stages of allergic skin response, and could have implications for human sufferers of atopic dermatitis. Atopic dermatitis (AD) is a type of eczema associated with allergic reactions and characterized by inflamed itchy patches of ...

Mayo Clinic researchers develop AI-ECG model to diagnose liver disease earlier

2025-12-17
ROCHESTER, Minn. — As rates of obesity, high blood pressure, type 2 diabetes and sleep apnea increase, cases of advanced chronic liver disease and resulting liver scarring or cirrhosis also are rising. Patients often are diagnosed based on symptoms, such as gastrointestinal bleeding, fluid retention or jaundice, which happen when liver disease has progressed to a late stage. This problem led Mayo Clinic researchers to develop an artificial intelligence (AI) model that resulted in twice the number of advanced chronic liver disease diagnoses in patients without symptoms, helping physicians treat them before the disease ...

Heavy menstruation common among teenage girls – questionnaire reveals risk of iron deficiency

2025-12-17
More than half of teenage girls experienced heavy bleeding and 40 per cent had an iron deficiency. The research, led from Lund University in Sweden, also shows that young teenage girls who experience heavy menstrual bleeding – and are therefore at greater risk of iron deficiency – can be identified using a simple questionnaire. As many as half of the teenage girls in the study published in PLOS One experienced heavy menstrual bleeding, and four out of ten had an iron deficiency. The 2023 study was carried ...

New study explores why open water swimming feels so powerful for midlife women

2025-12-17
Researchers at the University of East London have published a new study examining how middle-aged, middle-class British women describe the effects of regular open water swimming on their wellbeing, including its impact on symptoms of menopause. The research, published in the European Journal of Ecopsychology, uses in-depth interviews to understand women’s own accounts of swimming in outdoor water and how they feel it supports their lives. The study looks at the patterns that emerged when women talked about ...

In echo of Jurassic Park, mosquitoes capture entire ecosystems in their blood meals

2025-12-17
Jurassic Park — and its never-ending sequels and spinoffs — starts with a basic premise: extracting the DNA of long-dead dinosaurs from mosquitoes frozen in amber. It turns out mosquitoes really are as voracious as Michael Crichton imagined. A new study reveals that, within a small area in central Florida, mosquitoes fed on a whopping 86 different species of animals, capturing nearly all the vertebrate biodiversity in the area. “They say Jurassic Park inspired a new generation of paleontologists, ...

Marty Cooper, Illinois Tech Alumnus and ‘Father of the Cell Phone,’ Receives 2025 Marconi Society Lifetime Achievement Award

2025-12-17
CHICAGO—December 17, 2025—Illinois Institute of Technology (Illinois Tech) university life trustee Marty Cooper (EE ’50, M.S. ’57)—a pioneer in the field of mobile communications who’s considered the “Father of the Cell Phone”—has been awarded the 2025 Marconi Society Lifetime Achievement Award. Cooper, an Illinois Tech alumnus and former professor, was recognized for his lifetime of leadership in wireless communications, entrepreneurship, and public service, and for inspiring others through his work, mentorship, and ...

How to reduce the risk of lymphedema

2025-12-17
Lymphedema after head and neck cancer is considerably more common than previously assumed and can persist long after cancer treatment has finished. Researchers at Lund University in Sweden have discovered that patients with a low level of physical activity face a higher risk of developing lymphedema. They have also noted that a lymph scanner objectively measures changes in the condition – a method that has now been introduced in Sweden’s Southern Healthcare Region. Head and neck cancer is a collective term for several types of cancer that ...

NEJM Evidence and CIDRAP announce Public Health Alerts

2025-12-17
BOSTON and MINNEAPOLIS, December 17, 2025—NEJM Evidence and the University of Minnesota’s Center for Infectious Disease Research and Policy (CIDRAP), today launched Public Health Alerts, a new series published in NEJM Evidence and on CIDRAP’s site. Public Health Alerts deliver information and early warnings about emerging health threats, enabling swift, informed responses across the U.S. and globally. The first Public Health Alerts “Influenza Virus Characteristics in Department of Defense Populations, 2024 – 2025” and “Detection of Community Transmission of Clade Ib Mpox Virus in the United States” are now live and freely available ...

New fossil study illuminates on the evolutionary success of frogs

2025-12-17
A new study lead by UCC palaeontologists discovered that frogs have conserved their ecology in the last 45 million years. Dr Daniel Falk, together with colleagues from UCC, Germany and the United States, studied 45-million-year-old frogs from the Geiseltal fossil site in central Germany. Remarkably, the fossils preserve skin remnants and layers of microscopic fossilised cell structures called melanosomes. These cell structures synthesise, store, and transport melanin - the pigment responsible for skin, hair, and eye colour. Similar to modern frogs, these melanosomes occur in different body areas including the eyes, the internal organs and the ...

Patient-specific human liver model to understand disease mechanisms

2025-12-17
To the point: Three-dimensional multicellular human liver model: For the first time, a 3D human organoid model, developed with liver tissue from patients, consists of three liver cell types, derived from adult hepatocytes, cholangiocytes, and liver mesenchymal cells. Retaining structure and function: The novel complex organoid models, or assembloids, reconstruct essential structural and functional features of the human periportal liver region and have patient-specific traits. They capture key aspects of human liver physiology in a dish, including drug detoxification and metabolism. Liver disease investigation: When manipulated, ...

Confused by the doctor's questionnaire? U of A study suggests it's common

2025-12-17
Imagine sitting down for an appointment with a therapist – or any care provider. Perhaps it's the first time you've seen this provider, or the first time in a while. You'll likely need to fill out a form with a set of questions to ensure they know why you're there or how you're doing. Now imagine that the symptom questionnaire is quite confusing, to the point where you need to ask someone to clarify what the questions are asking. Many people don't have to imagine – this confusion is common, according to a study led by a University of Arizona psychologist. Questionnaires like these have been the standard since the 1990s. The Patient Health ...

How do brains stay stable, and when might a dose of flexibility be helpful?

2025-12-17
LA JOLLA (December 17, 2025)—Young minds are easily molded. Each new experience rewires a child’s brain circuitry, adding and removing synaptic connections between neurons. These wiring patterns become more stable with age, but biology has left some wiggle room to ensure that adult brains can still adapt and refine their circuitry as needed. This flexibility is called neuroplasticity, and our ability to learn, make new memories, and recover from injury all depend on it. So how does your brain ...

mRNA revitalizes aging immune systems—the liver as a fountain of youth

2025-12-17
Can the weakened immune systems of older individuals be rejuvenated? Researchers from the German Cancer Research Center (DKFZ), the HI-STEM* institute, and the Broad Institute have demonstrated that this is possible with an innovative approach. In a study now published in Nature, the team showed that mRNA technology can be used to transform the liver in mice into a temporary source of important immune regulatory factors that are naturally lost during aging. This restores the formation of new immune cells, allowing older animals ...

Rural-urban differences in the prevalence of chronic pain among adult cancer survivors

2025-12-17
About The Study: The multivariable findings of this study showed that chronic pain was more prevalent among rural than urban cancer survivors even after controlling for covariates, suggesting an association between chronic pain and additional factors. For example, survivorship resources are generally less available in rural areas, and rural residents may lack access to pain specialists or face insurance challenges accessing pain care. Corresponding Author: To contact the corresponding author, Erika Ziller, PhD, email erika.ziller@med.uvm.edu. To access the embargoed study: Visit our For The Media website at this ...

Food insecurity, burnout, and social isolation among resident and fellow physicians

2025-12-17
About The Study: In this cross-sectional study, nearly 1 in 7 graduate medical education trainees screened positive for food insecurity. Food insecurity was associated with important well-being outcomes including burnout. These findings suggest that academic medical institutions should pursue systemic solutions to address food insecurity among resident and fellow physicians as a means of supporting their well-being. Corresponding Author: To contact the corresponding author, Larissa R. Thomas, MD, MPH, email larissa.thomas@ucsf.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2025.50044) Editor’s ...

How do spinal cord injuries heal?

2025-12-17
Cedars-Sinai investigators have discovered a healing mechanism that could one day be harnessed to help treat patients with spinal cord injuries, stroke, and neurological conditions such as multiple sclerosis. Their study, published in Nature, describes a previously unknown function of astrocytes, a type of cell in the central nervous system. “Astrocytes are critical responders to disease and disorders of the central nervous system—the brain and spinal cord,” said neuroscientist Joshua Burda, PhD, assistant professor of Biomedical Sciences ...

Detailed cell map unlocks secrets of how reproductive organs form

2025-12-17
New research has mapped the cell types that specialise to form reproductive organs in both sexes, identifying key genes and signals that drive this process. The findings offer important insights into conditions affecting the reproductive organs, and how environmental chemicals may affect reproductive health. Researchers at the Wellcome Sanger Institute and EMBL’s European Bioinformatics Institute (EMBL-EBI) used a combination of single-cell and spatial genomics technologies to analyse over half a million individual human cells from the developing reproductive system.  Published today (17 December) in Nature, the study provides the most ...

Large language models unleash AI’s potential for autonomous and explainable materials discovery

2025-12-17
Tokyo, Japan – Discovering new inorganic materials is central to advancing technologies in catalysis, energy storage, semiconductors, and more. But finding a material with just the right properties is extremely difficult. What if an AI system could think like a human expert, explore this enormous space automatically, and suggest promising new materials on its own? In a study published this month in Cell Reports Physical Science, researchers from the Institute of Industrial Science, The University of Tokyo announced the development of MatAgent, an AI framework ...

Gut bacteria have evolved rapidly to digest starches in ultra-processed foods

2025-12-17
Gut bacteria evolve rapidly in response to different diets, UCLA evolutionary biologists report in a new study. The researchers found that gene variants that help microbes digest starches found in ultra-processed foods have “swept” the genomes of some species of gut bacteria in industrialized parts of the world. Because these starches are industrially produced and have only been around for a few decades, scientists believe natural selection must have been acting strongly to make these genes dominant so quickly. What’s ...

New risk score helps predict pancreatic cancer recurrence

2025-12-17
Cedars-Sinai investigators, leading a multi-institutional team, have developed and validated a tool to predict which patients with pancreatic neuroendocrine tumors (PanNETs) need closer monitoring because their cancer is more likely to recur. The findings, published in JAMA Surgery, provide a framework to better manage ongoing follow-up care of patients whose cancer has not spread to their lymph nodes and who have had their tumors surgically removed. “We now have a way to identify patients whose higher risk of recurrence may have ...

New evidence challenges understanding of Parkinson’s disease

2025-12-17
A McGill-led study is challenging a popular theory about how dopamine drives movement, a discovery that could shift how scientists think about Parkinson’s disease treatments.  Published in Nature Neuroscience, the research found dopamine does not set the speed or force of each movement, as had been thought. Instead, it appears to act as the underlying support system that makes movement possible.  “Our findings suggest we should rethink dopamine’s role in movement,” said senior author Nicolas Tritsch, Assistant Professor in McGill’s Department of Psychiatry and researcher at the Douglas Research Centre. “Restoring ...

A new study reveals how embryos and the uterus “talk” during implantation

2025-12-17
A new study shows that the embryo and the uterine lining conduct an active “conversation” from the very earliest stages of implantation. They engage in a back and forth of tiny packages called extracellular vesicles and lipid droplets, which carry metabolites and signals. Hormones determine what the uterus sends, and one signalling pathway (related to aryl hydrocarbon receptor, [AhR]) appears to assist in determining how hospitable the uterine environment is. When this pathway is blocked, embryos attach more strongly. These packages are taken up quickly; ...

Cedars-Sinai reports heart attacks, general illness spiked after LA fires

2025-12-17
Correction, December 16, 2025: An earlier version of this news release incorrectly stated investigators found a 218% increase in visits for general illness. The correct statistic, based on the study, is 118%.  An unusually high number of people developed a heart attack, lung complication or general illness within 90 days after the start of the January 2025 fires in Los Angeles, a new study from Cedars-Sinai reports.  “Wildfires that spread into urban areas have proven to be extremely ...
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