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Post-traumatic stress symptoms can cause problems in the bedroom for midlife women

2023-09-27
CLEVELAND, Ohio (Sept 27, 2023)—Post-traumatic stress disorder (PTSD) has been associated with a number of adverse mental and physical health outcomes. Little is known, however, regarding its impact on sexual functioning among midlife women. A new study is shedding light on the topic, suggesting that greater PTSD symptoms lead to worse sexual functioning. Study results will be presented during the 2023 Annual Meeting of The Menopause Society in Philadelphia, September 27-30. PTSD is more common among women than many ...

The effects of sexual orientation on sexual function and distress

2023-09-27
CLEVELAND, Ohio (Sept 27, 2023)—In recent years, there has been debate around the topic of who is happier, healthier, and more satisfied sexually—traditional heterosexual or sexual minority women. A new study suggests that cisgender heterosexual women have higher relationship scores and less anxiety and depression than their less traditional counterparts. Study results will be presented during the 2023 Annual Meeting of The Menopause Society in Philadelphia September 27-30. Satisfaction with one’s relationship and sex life has been shown to ...

Hot flashes linked with risk factors for cardiovascular disease

2023-09-27
CLEVELAND, Ohio (Sept 27, 2023)—Hot flashes have long been known to be linked to a number of adverse health effects. Emerging data suggests an association between them and cardiovascular disease. A new study is the first to link physiologically assessed hot flashes with heightened systemic inflammation which is a risk factor for heart disease. Study results will be presented during the 2023 Annual Meeting of The Menopause Society in Philadelphia September 27-30. Vasomotor symptoms, more often referred to as hot flashes, are one of the most common symptoms identified during the menopause transition, with roughly 70% of midlife ...

The impact of menopause stage on age-related changes in the brain

2023-09-27
CLEVELAND, Ohio (Sept 27, 2023)—Driven by changing estrogen levels, the menopause transition has a major influence on physiology during aging. Estrogen receptors populate numerous brain regions which explains why cerebral glucose metabolism is affected during the perimenopause stage. A new study investigated the association between the menopause stage and cerebral hemodynamics during typical aging. Study results will be presented during the 2023 Annual Meeting of The Menopause Society in Philadelphia September 27-30. It has been suggested that changes in cerebral physiology during aging may ...

What your hair and saliva say about your risk for depression and cognitive shortfalls during menopause

2023-09-27
CLEVELAND, Ohio (Sept 27, 2023)—Stress affects the body and brain in many ways by causing the endocrine system to increase cortisol levels. These spiked levels can be found throughout the body. A new study suggests that elevated cortisol levels in the hair and saliva may affect cognitive and mental health in late peri/early postmenopausal women. Study results will be presented during the 2023 Annual Meeting of The Menopause Society in Philadelphia September 27-30. It’s no secret that stress can take a major toll on the body and ...

Obese women have worse menopause symptoms nd get less relief from hormone therapy

2023-09-27
CLEVELAND, Ohio (Sept 27, 2023)—Obesity has already been associated with a number of adverse health conditions and can interfere with a person’s quality of life. A new study suggests that, in addition to these other problems, it may also worsen a woman’s menopause symptoms and limit the amount of relief she gets from hormone therapy (HT). Study results will be presented during the 2023 Annual Meeting of The Menopause Society in Philadelphia, September 27-30. HT remains the most effective ...

New research identifies genetic links between schizophrenia and cardiovascular disease risk factors

2023-09-27
WASHINGTON, D.C., Sept. 27, 2023 — New research finds that people with schizophrenia have a genetic propensity to smoking and a reduced genetic risk of obesity. The study, published in The American Journal of Psychiatry, revealed genetic overlap between schizophrenia and cardiovascular disease (CVD) risk factors, particularly body mass index (BMI) and smoking. The findings highlight the importance of environmental factors in the development of obesity and other CVD comorbidities. Schizophrenia is associated with an increased ...

Workshop synthesis paper describes value of prescribed fire in wilderness areas

Workshop synthesis paper describes value of prescribed fire in wilderness areas
2023-09-27
GUNNISON, Colorado, September 18, 2023 - Many of the wilderness areas that we treasure were historically shaped by fire. Yet today, many wilderness landscapes are caught in the wildfire paradox – widespread suppression and exclusion of burning over the last century have increased the likelihood of high-intensity fires, which are more damaging rather than restorative. In December of 2022, experts from land management agencies, Tribes, and organizations across the country convened at the Wilderness and Fire Workshop in Gunnison to consider solutions to this dilemma, including the use of prescribed fire. Today, ...

Patients who quit smoking after percutaneous coronary intervention do as well as non-smokers – unless they had smoked heavily

Patients who quit smoking after percutaneous coronary intervention do as well as non-smokers – unless they had smoked heavily
2023-09-27
Patients who quit smoking after undergoing percutaneous coronary intervention (PCI) for narrowed arteries have similar outcomes as non-smokers during four years of follow-up after the procedure, according to a large study published in the European Heart Journal [1] today (Wednesday). However, if they had been heavy, long-term smokers, no improvement was seen.   The study of 74,471 patients who had a PCI between 2009 and 2016 is the first, large population-based study to examine the impact of smoking on cardiovascular outcomes, such as death, heart ...

USC launches liver disease study as part of $50.3 million “multi-omics” consortium

2023-09-27
The Keck School of Medicine of USC has received funding from the National Institutes of Health as part of a five-year, $50.3 million “multi-omics” study of human health and disease involving six sites. Researchers in the Multi-Omics for Health and Disease consortium will study fatty liver disease, hepatocellular carcinoma, asthma, chronic kidney disease, preeclampsia and other conditions, with a focus on underrepresented racial and ethnic groups. Throughout the study, researchers will use ...

How silencing a gene-silencer could lead to new cancer drugs

2023-09-27
Deep inside our cells—each one complete with an identical set of genes—a molecular machine known as PRC2 plays a critical role in determining which cells become heart cells, versus brain or muscle or skin cells. When the machine is missing or broken, normal fetal development can’t occur. If it’s mutated, cells can grow uncontrollably, and cancer can arise—a fact that has made PRC2 a source of keen interest for drug developers. New research by scientists at CU Boulder and Harvard Medical School offers an unprecedented ...

A novel role discovered for vagus nerve

A novel role discovered for vagus nerve
2023-09-27
The vagus nerve, known for its role in ‘resting and digesting’, has now been found to have an important role in exercise, helping the heart pump blood, which delivers oxygen around the body. Currently, exercise science holds that the ‘fight or flight’ (sympathetic) nervous system is active during exercise, helping the heart beat harder, and the ‘rest and digest’ (parasympathetic) nervous system is lowered or inactive. However, University of Auckland physiology Associate Professor Rohit Ramchandra says that this current understanding is based on indirect estimates and a number of assumptions their new study has ...

THE LANCET: Gender inequalities worsen women’s access to cancer prevention, detection and care; experts call for transformative feminist approach

THE LANCET: Gender inequalities worsen women’s access to cancer prevention, detection and care; experts call for transformative feminist approach
2023-09-27
Peer reviewed / Review, analysis and opinion Cancer is a leading cause of mortality in women and ranks in the top three causes of premature death (under age 70) in women in almost every country worldwide. New analysis finds, of the 2.3 million women who die prematurely from cancer each year, 1.5 million lives could be saved through the elimination of exposures to key risk factors or via early detection and diagnosis, while a further 800 000 deaths could be prevented if all women could access optimal ...

Prolonged mismatch between calories eaten and burned may be putting many athletes at risk of REDs (Relative Energy Deficiency in Sport)

2023-09-27
The estimated prevalence of REDs varies by sport, ranging from 15% to 80%. The syndrome often goes unrecognised by athletes themselves, their coaches, and team clinicians, and may unwittingly be exacerbated by the ‘sports culture,’ because of the perceived short term gains on performance from intentionally or unintentionally limiting calorie intake, warns the Statement. REDs was first recognised as a distinct entity by the IOC in a 2014 consensus statement. This latest consensus, informed by a panel of international experts, draws on key advances in REDs science ...

Government policies work to reduce greenhouse gas emissions

2023-09-27
Policies designed to reduce greenhouse gas emissions have been effective, however more stringent regulations are needed to limit global warming to the Paris temperature goals, finds a new analysis by UCL researchers of international efforts to fight climate change. The research, published in Annual Reviews of Environment and Resources, tracked the rate of greenhouse gas emissions over the last two decades against global efforts to reduce them. Since the early 2000s, governments around the world have enacted numerous regulations to curb greenhouse gas emissions. Over the same ...

Researchers combat Zika-associated fetal abnormalities using microRNA

2023-09-26
Before SARS-CoV-2 and the COVID-19 pandemic, there was the Zika virus epidemic, lasting from 2015 to 2016. The Zika virus can cause serious birth defects and abnormalities. During the epidemic, one of the most striking results of Zika virus in pregnant women was the increase in offspring with microcephaly or a head much smaller than expected, a condition that can result in abnormal brain development. While the Zika virus epidemic has ended, future outbreaks are inevitable as most of the world’s population lives in areas where the Zika virus mosquito thrives. Researchers in the Aagaard Lab at Baylor College of Medicine ...

Double trouble: Infamous “eagle killer” bacterium produces not one, but two toxins

Double trouble: Infamous “eagle killer” bacterium produces not one, but two toxins
2023-09-26
The cyanobacterium Aetokthonos hydrillicola produces not just one, but two highly potent toxins. In the latest issue of the journal Proceedings of the National Academy of Sciences (PNAS), an international team led by Martin Luther University Halle-Wittenberg (MLU) and Freie Universität Berlin describes the second toxin, which had remained elusive until now. Even in low concentrations, it can destroy cells and is similar to substances currently used in cancer treatment. Two years ago, the same team established that the first toxin from the cyanobacterium is the cause of a mysterious disease among bald eagles in the USA. Aetokthonos hydrillicola is ...

Study finds link to unclean cooking fuels and developmental delays in children

2023-09-26
BUFFALO, N.Y. – Just about everyone knows that cigarette smoke is bad for babies. Should cooking fuels like natural gas, propane and wood be viewed similarly when used indoors? That’s the takeaway from a new study led by University at Buffalo researchers, who looked at indoor air pollution exposure and early childhood development in a sample of more than 4,000 mother-child pairs in the U.S. “Exposure to unclean cooking fuel and passive smoke during pregnancy and in early life are associated with developmental delays in ...

Smart carts could detect fire hazards in nuclear facilities

Smart carts could detect fire hazards in nuclear facilities
2023-09-26
A University of Texas at Arlington researcher is working with a not-for-profit cooperative to develop and test a smart, automated cart that could replace humans who conduct fire hazard safety checks in nuclear power facilities. Chan Kan, a UT Arlington assistant professor in the Department of Industrial, Manufacturing and Systems Engineering (IMSE), will lead the $250,000 project with the cooperative Utilities Service Alliance. “We will develop and build a cart with state-of-the-art equipment that could replace human testing of nuclear facilities,” Kan said. Currently, when the primary fire-sensing system fails or ...

Understanding of mechanisms behind post-exercise lack of appetite can open new paths to obesity treatment

2023-09-26
The complex relationship between physical activity and energy balance – food intake versus energy expenditure – is still a challenge for science, especially in light of the rising worldwide prevalence of overweight and obesity. Some of the medications available on the market to combat obesity work analogously to hormones associated with appetite control, and for some time researchers have focused on understanding how processes involving metabolites (products of cell metabolism) affect hunger and satiety. A ...

Living donor liver transplant access is optimal for high-risk waitlisted cirrhosis patients

Living donor liver transplant access is optimal for high-risk waitlisted cirrhosis patients
2023-09-26
“Access to LDLT in a transplant program can optimize the timing of transplant for the increasingly older, frail patient population [...]” BUFFALO, NY- September 26, 2023 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 17, entitled, “Availability of living donor optimizes timing of liver transplant in high-risk waitlisted cirrhosis patients.” Liver transplant (LT) candidates have become older and frailer. Growing non-alcoholic steatohepatitis ...

ACC releases guide to home-based cardiac care

2023-09-26
The health care landscape has undergone rapid changes in recent years, requiring clinicians and stakeholders to consider innovative ways to provide care in traditional and non-traditional settings. The American College of Cardiology has released a workbook on home-based cardiac care that provides the cardiovascular care team with tools and resources to incorporate high-quality, patient-centered care in the home setting. Home-based care is defined as any form of medical care that takes place in the home of the patient; this includes the acceleration of virtual ...

Transgenic T cells against malignant brain tumors

2023-09-26
Scientists from the German Cancer Research Center (DKFZ) and the University Medical Center Mannheim (UMM) successfully tested a new form of cellular immunotherapy against brain tumors in mice for the first time. Glioblastomas are the most aggressive of all brain tumors. They spread diffusely in the brain and are difficult to remove completely by surgery. Chemotherapy or radiation therapy also often have limited effectiveness. To find new, more effective treatment options for those affected, doctors and scientists are testing numerous immunotherapeutic approaches, including so-called "adoptive" T-cell therapies: This involves isolationg ...

Aston University research pioneers making renewable hydrogen and propane fuel gases from glycerol

Aston University research pioneers making renewable hydrogen and propane fuel gases from glycerol
2023-09-26
  Research shows way forward for making renewable hydrogen from glycerol Crude glycerol from biodiesel production plants cheap and abundant Could benefit the environment and reduce reliance on fuel imports.   26 September 2022 | Birmingham, UK   Aston University research has shown the way forward for making renewable hydrogen and propane fuel gases from glycerol. An organic compound, glycerol is produced mainly from fats and oils and is often used in health and beauty products. With crude glycerol from biodiesel production plants cheap and abundant the researchers have ...

SRI spins off AI-powered drug discovery platform Synfini, Inc.

SRI spins off AI-powered drug discovery platform Synfini, Inc.
2023-09-26
SRI International announced today it is spinning off Synfini, a biosciences platform that accelerates the process by which pharmaceutical and other companies can design, synthesize, and bring to market molecules for drug development. The technology brings together a suite of software and hardware solutions developed at SRI through a significant, multi-year development effort. The suite includes a neuro-symbolic AI molecule designer, a computational synthetic planning tool, a high-throughput automated chemistry system, and a flow chemistry hardware platform that reliably performs multi-step synthesis. “At SRI we are always tremendously excited to ...
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