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Pennington Biomedical researchers explore factors behind body’s ability to regulate weight

2026-01-13
BATON ROUGE, La. – Pennington Biomedical researchers recently investigated the systems of the body that regulate weight, exploring whether our bodies defend an established weight target or if our bodies operate within a broader range of tolerance before biological mechanisms are activated. The paper, titled “Body weight regulation models in humans: insights for testing their validity,” which was recently published in Nature Reviews Endocrinology, examined competing body weight regulation models and analyzed how energy intake and expenditure interact ...

Zhongping Lee awarded the Nils Gunnar Jerlov Medal

2026-01-13
The Oceanography Society has selected Dr. Zhongping Lee of Xiamen University as the recipient of the 2026 Nils Gunnar Jerlov Medal, recognizing his transformative contributions to understanding how light interacts with the ocean, as well as his sustained leadership in education, interdisciplinary research, and collaborative work with meaningful societal impact. Dr. Lee will be recognized at The Oceanography Society Honors Breakfast, February 24, 2026, during the Ocean Sciences Meeting in Glasgow, Scotland, as well as during the Ocean Optics XXVII Conference in Ghent, Belgium, in September 2026. Awarded biennially, the ...

Deborah S. Kelley awarded the Wallace S. Broecker Medal

2026-01-13
Deborah S. Kelley, Professor in the School of Oceanography at the University of Washington, has been awarded the Wallace S. Broecker Medal by The Oceanography Society. This honor recognizes her innovative and impactful contributions to marine geoscience and chemical oceanography, her leadership in interdisciplinary and collaborative research, and her sustained commitment to education and mentorship. Dr. Kelley will receive this honor at The Oceanography Society Honors Breakfast, February 24, 2026, during the Ocean Sciences Meeting in Glasgow, Scotland, and will also present a plenary lecture during the society awards session on February ...

Novel immunotherapy demonstrates early potential to overcome resistance to immune checkpoint therapy

2026-01-13
According to a Phase I study led by researchers at The University of Texas MD Anderson Cancer Center, published today in Nature Medicine, the novel monoclonal antibody linavonkibart demonstrated the potential to overcome treatment resistance to anti-PD-1 immune checkpoint inhibitors in multiple cancer types. The trial was led by Timothy Yap, M.B.B.S., Ph.D., professor of Investigational Cancer Therapeutics and vice president and head of clinical development in MD Anderson’s Therapeutics Discovery division. “This ...

LLM treatment advice agrees with physician recommendations in early-stage HCC, but falls short in late stage

2026-01-13
Large language models (LLM) can generate treatment recommendations for straightforward cases of hepatocellular carcinoma (HCC) that align with clinical guidelines but fall short in more complex cases, according to a new study by Ji Won Han from The Catholic University of Korea and colleagues publishing January 13th in the open-access journal PLOS Medicine. Choosing the most appropriate treatment for patients with liver cancer is complicated. While international treatment guidelines provide recommendations, clinicians must tailor their treatment choice based on cancer stage and liver function as well as other factors such as comorbidities. To assess whether LLMs can provide treatment ...

Deep learning model trained with stage II colorectal cancer whole slide images identifies features associated with risk of recurrence – with higher success rate than clinical prognostic parameters

2026-01-13
In your coverage, please use this URL to provide access to the freely available paper in PLOS Medicine: https://plos.io/48KLRz7   Article title: Multiview deep-learning-enabled histopathology for prognostic and therapeutic stratification in stage II colorectal cancer: A retrospective multicenter study Author countries: China, United States Funding: see manuscript END ...

Aboard the International Space Station, viruses and bacteria show atypical interplay

2026-01-13
In a new study, terrestrial bacteria-infecting viruses were still able to infect their E. coli hosts in near-weightless “microgravity” conditions aboard the International Space Station, but the dynamics of virus-bacteria interactions differed from those observed on Earth. Phil Huss of the University of Wisconsin-Madison, U.S.A., and colleagues present these findings January 13th in the open-access journal PLOS Biology. Interactions between phages—viruses that infect bacteria—and their hosts play an integral role in microbial ecosystems. Often described as being in an ...

Therapies that target specific type of cell death may be an effective avenue for cancer treatment, UTHealth Houston researchers find

2026-01-13
Therapies that target the utilization of fat by tumors and activate a type of cell death dependent on fat molecules may be a promising avenue to treat cancer, according to new research by UTHealth Houston. The findings were published today in Trends in Cancer and were co-led by Daniel E. Frigo, PhD, professor at  The University of Texas MD Anderson Cancer Center and a faculty member at The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences. Researchers came to the conclusion through a review of 121 outside studies that examined the relationship between ...

CHEST releases guideline on biologic management in severe asthma

2026-01-13
Glenview, Illinois –The American College of Chest Physicians® (CHEST) recently released a new clinical guideline on biologic management in severe asthma. Published in the journal CHEST®, the guideline contains seven evidence-based recommendations to provide a framework for pulmonologists, allergists, and immunologists to implement in their own practice.  Severe asthma affects 5% to 10% of patients with asthma, which is defined as patients who require high-dose ...

Scientists create a system for tracking underwater blackouts

2026-01-13
(Santa Barbara, Calif.) — Clouds, smoke and fog may darken the skies, but sediment, algae blooms and organic matter can turn day into night on the seafloor. That’s why an international team of scientists have created the first framework to identify and compare these marine blackouts. The study, published in Communications Earth & Environment, introduces the concept of a marine darkwave: a short-term but intense episode of underwater darkness that can severely impact kelp forests, seagrass beds and other light-dependent ...

Fruit fly pigmentation guides discovery of genes that control brain dopamine and sleep

2026-01-13
Dopamine in the brain influences movement, learning, motivation and sleep. In humans, problems with dopamine are linked to conditions like Parkinson’s disease, depression and sleep disorders. While scientists know a great deal about how dopamine works in the brain, they know less about how the body controls dopamine levels. Understanding this could help treat diseases where dopamine is disrupted. In a new study published in iScience, researchers at Baylor College of Medicine and the Jan and Dan Duncan Neurological Institute at Texas Children’s Hospital (Duncan NRI) worked with the laboratory fruit fly to find new genes involved in regulating dopamine ...

World's largest physics conference to be held in Denver and online this March

2026-01-13
More than 14,000 physicists from around the world will convene to present groundbreaking research at the American Physical Society’s Global Physics Summit. The conference will be held in person in Denver and online everywhere March 15-20. Scientific program The scientific program includes more than 12,000 individual presentations on new research in astrophysics, particle physics, quantum information science, biological physics, energy research, and more. For more information, search the scientific program. All times are in Mountain time. Hybrid format The Global Physics Summit will have both in-person and online experiences. The in-person ...

New mega-analysis reveals why memory declines with age

2026-01-13
A landmark international study that pooled brain scans and memory tests from thousands of adults has shed new light on how structural brain changes are tied to memory decline as people age. The findings — based on more than 10,000 MRI scans and over 13,000 memory assessments from 3,700 cognitively healthy adults across 13 studies — show that the connection between shrinking brain tissue and declining memory is nonlinear, stronger in older adults, and not solely driven by known Alzheimer’s-associated genes like ...

Understanding ammonia energy’s tradeoffs around the world

2026-01-13
Many people are optimistic about ammonia’s potential as an energy source and carrier of hydrogen, and though large-scale adoption would require major changes to the way it is currently manufactured, ammonia does have a number of advantages. For one thing, ammonia is energy-dense and carbon-free. It is also already produced at scale and shipped around the world, primarily for use in fertilizer. Though current manufacturing processes give ammonia an enormous carbon footprint, cleaner ways to make ammonia do exist. A better understanding of how to guide the ammonia fuel industry’s continued development ...

UTHealth Houston researchers map gene disruptions in sporadic early onset Alzheimer’s disease across key brain regions

2026-01-13
A new study led by researchers at UTHealth Houston investigated both gene expression and regulation at single cell levels to reveal disruptions in gene function in three brain regions of patients with sporadic early onset Alzheimer’s disease. The findings were published in Science Advances. Only about 5% to 10% of patients with Alzheimer’s disease are younger than 65. Of those patients, 10% have mutations in the APP, PSEN1, and PSEN2 genes, which are associated with Alzheimer’s disease. The other 90% of these cases are classified as sporadic early onset Alzheimer’s, a rare and aggressive form of the ...

Minimum wage increases are linked to safer pregnancies

2026-01-13
Increases to the minimum wage may do more than bolster household income, reduce inequality and enhance worker well-being: They may also help make pregnancies safer, according to new research from Rutgers University. A study published online ahead of the Fe in the American Journal of Preventive Medicine finds that state-level increases in the minimum wage are associated with lower rates of hypertensive disorders of pregnancy, a leading cause of maternal mortality in the United States. The study, led by Slawa Rokicki, an assistant professor at the Rutgers School of Public Health, ...

Left in the cold: Study finds most renters shut out of energy-saving upgrades

2026-01-13
As winter heating costs rise, new research from Binghamton University, State University of New York reveals a cold truth. Renters – who make up approximately ⅓ of the U.S. population – are missing out on energy efficiency improvements that could lower their bills, make their apartments more comfortable and improve their health. This study, “Still muddling through: Local sustainability leaders and energy efficiency in rental units,” was published in Energy Research & Social Science. ...

This crystal sings back: Illinois collaboration sheds light on magnetochiral instability

2026-01-13
Researchers from The Grainger College of Engineering at the University of Illinois Urbana-Champaign have reported the first observation of a dynamic magnetochiral instability in a solid-state material. Their findings, published in Nature Physics, bridge ideas from nuclear and high-energy physics with materials science and condensed matter physics to explain how interplay between symmetry and magnetism can amplify electromagnetic waves. A material’s behavior is heavily influenced ...

Organisms in the Atacama Desert soil are remarkably diverse

2026-01-13
A new study shows that resilient and remarkably diverse populations of organisms can persist in the soil despite harsh and extremely dry conditions. An international team led by researchers from the University of Cologne, has examined tiny nematodes in the Chilean Atacama Desert. Along with the polar regions, the Atacama Desert is considered one among these most arid regions in the world. Lack of rainfall, high salt content in the soil, and extreme temperature fluctuations make it one of the most hostile places on earth. The interdisciplinary team with researchers from the fields of zoology, ecology and botany demonstrated the strategies used by different nematodes ...

Children’s Hospital Colorado research outlines first pediatric classifications for suicide risk in adolescents and kids

2026-01-13
AURORA, Colo. (January 13, 2025) – Today, pediatric experts from Children’s Hospital Colorado (Children’s Colorado) announced published research in the Journal of the American Academy of Child and Adolescent Psychiatry that identifies five classifications of youth who have died by suicide. Using 10 years of national suicide data, Joel Stoddard, MD, MAS, child and adolescent psychiatrist at Children’s Colorado, and his team found that nearly half of youth who died by suicide did not have clinical contact or a known ...

No thyme wasted: Harnessing the medicinal benefits of thyme extract With small doses

2026-01-13
WASHINGTON, Jan. 13, 2026 — With a myriad of health effects, thyme extract may seem like a magic medicinal ingredient. Its biologically active compounds — thymol, carvacrol, rosmarinic acid, and caffeic acid — provide anti-inflammatory, antimicrobial, antioxidant, and immune benefits. But thyme extract also has downsides. It vaporizes quickly (a waste of thyme!), making it challenging to use, and too much of it can be irritating, causing rashes and digestive issues. A solution to both problems is to encapsulate nanodroplets of thyme extract within another fluid, ...

Fat surrounding the colon interacts with the immune system

2026-01-13
Abdominal fat is not a uniform tissue. A new study from Karolinska Institutet, Steno Diabetes Center Copenhagen, and Helmholtz Munich reveals that fat located close to the large intestine contains an unusually high number of inflammatory fat cells and immune cells. The findings suggest that this tissue is specially adapted to communicate with the immune system in the gut region. The study is published in the journal Cell Metabolism. In the study, researchers mapped five different abdominal fat depots in individuals with severe obesity. The results show clear differences between these depots. Most striking is the so-called epiploic fat tissue along the ...

Genetic predisposition to excess body weight and survival in women diagnosed with breast cancer

2026-01-13
About The Study: In this cohort of nonmetastatic breast cancer survivors, women who were genetically predisposed to having a higher body mass index were at increased risk of all-cause mortality. Targeted lifestyle recommendations to mitigate their genetic predisposition should be considered to lower this risk. Corresponding Author: To contact the corresponding author, Clara Bodelon, PhD, MS, email clara.bodelon@cancer.org. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2025.53687) Editor’s Note: Please ...

New mechanism links Epstein-Barr virus to MS

2026-01-13
The immune system’s reaction to the common Epstein-Barr virus can ultimately damage the brain and contribute to multiple sclerosis (MS). This is shown by new research from Karolinska Institutet, published in Cell. The study provides new insight into the long-suspected link between Epstein-Barr virus (EBV) and MS. Multiple sclerosis is a chronic inflammatory disease in which the immune system attacks the central nervous system and causes nerve damage. It has long been known that everyone who develops MS has had an infection with the Epstein-Barr virus (EBV) – a common virus that often infects young people, sometimes causing glandular fever but ...

Genetic risk factor and viral infection jointly contribute to MS

2026-01-13
One of the leading triggers for multiple sclerosis (MS) is an infection with the Epstein-Barr virus. However, certain gene variants also play an important role. Researchers at the University of Zurich have now shown that it is the molecular interaction between environmental and genetic risk factors that ultimately triggers the disease. Recent findings suggest that the Epstein-Barr virus (EBV) is involved in both causing multiple sclerosis (MS) and shaping its progression. Everyone who has MS has previously ...
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