A hidden immune circuit in the uterus revealed: Findings shed light on preeclampsia and early pregnancy failure
BIRMINGHAM, Ala. – Early pregnancy depends on a remarkable act of coordination. Before the placenta can nourish a growing fetus, the embryo must securely “land” and connect with the mother’s blood supply — a process guided by a specialized group of immune cells called uterine natural killer cells, or uNK cells.
A new peer-reviewed study from the University of Alabama at Birmingham, supported by the National Institutes of Health and published today in Science Translational Medicine, has uncovered a critical role in successful pregnancies for an immune switch ...