How a gift card could help speed up Alzheimer’s clinical research
2025-08-22
Offering a modest gift card significantly increased enrollment of low-income individuals in a patient registry designed to accelerate Alzheimer’s disease clinical trials, a new USC study finds.
Why it matters: Effective strategies are needed to improve representation of marginalized groups in Alzheimer’s clinical trials. Despite ongoing debate among researchers about the ethics of financial incentives for clinical trial enrollment, there has been little consensus on the appropriate use and size of incentives.
About the experiment: Nearly 50,000 adults 50 and older without a dementia diagnosis were invited over ...
Depression and anxiety symptoms in adults displaced by natural disasters
2025-08-22
About The Study: This study found that, in U.S. adults, disaster-induced displacement from home was associated with increased odds of depression and anxiety symptoms, with the highest odds among those who never returned home. There is an urgent need to address mental health care for populations displaced by natural disasters, particularly socially vulnerable populations.
Corresponding Author: To contact the corresponding author, Ther W. Aung, PhD, email twa21@case.edu.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamanetworkopen.2025.28546)
Editor’s ...
Cardiovascular health at the intersection of race and gender in Medicare fee for service
2025-08-22
About The Study: This cross-sectional study found that Asian and Pacific Islander, Black, and Hispanic transgender and gender diverse beneficiaries had a high prevalence of cardiovascular-related conditions and had an elevated prevalence of several conditions, attributable to the intersection of gender, race, and ethnicity. Medicare should use the tools at its disposal to support the health of transgender and gender diverse beneficiaries.
Corresponding Author: To contact the corresponding author, Gray Babbs, MPH, ...
World’s first observation of the transverse Thomson effect
2025-08-22
For the first time in the world, a joint research team from NIMS, Nagoya University and The University of Tokyo has successfully observed the transverse Thomson effect—a phenomenon in which metals or semiconductors release or absorb heat when a heat current, charge current and magnetic field are applied orthogonally to each other. This achievement may contribute to advances in physics and materials science related to the conversion between heat, electricity and magnetism, as well as to the development of new thermal management technologies. The research was published in Nature ...
Powerful nodes for quantum networks
2025-08-22
Quantum networks are often described as the future of the internet — but instead of transmitting classical information in bits, they send quantum information carried by photons. These networks could enable ultra-secure communication, link together distant quantum computers into a single, vastly more powerful machine, and create precision sensing systems that can measure time or environmental conditions with unprecedented accuracy.
To make such a network possible, so-called quantum network nodes — that can store ...
Mapping fat: How microfluidics and mass spectrometry reveal lipid landscapes in tiny worms
2025-08-22
Understanding how fat molecules are distributed and function in living organisms is key to uncovering mechanisms of aging, disease, and metabolism. Caenorhabditis elegans, a transparent roundworm, is a widely used model for studying fat storage due to its genetic similarity to humans and well-defined anatomy. However, visualizing lipids at high resolution in such a small organism has posed a major technical challenge.
A research team at Okayama University, Japan, led by Professor Masazumi Fujiwara and his PhD student Ms. Sara Mandic, in collaboration with Professor Ron M. A. Heeren of ...
ATOX1 promotes hepatocellular carcinoma carcinogenesis via activation of the c-Myb/PI3K/AKT signaling pathway
2025-08-22
Background and Aims
Despite advancements in diagnostic and therapeutic strategies, hepatocellular carcinoma (HCC) remains a leading cause of cancer-related mortality. Antioxidant-1 (ATOX1) has been implicated in oncogenic processes across various cancer types; however, its specific role in HCC remains unclear. This study aimed to investigate the function of ATOX1 and its underlying molecular mechanisms in HCC.
Methods
Immunohistochemical analysis was conducted to assess ATOX1 expression in HCC tissues. Cell Counting ...
Colibactin-producing E. coli linked to higher colorectal cancer risk in FAP patients
2025-08-22
Researchers from Kyoto Prefectural University of Medicine and collaborating Japanese institutions found that patients carrying colibactin-producing Escherichia coli (pks+ E. coli) in their colon polyps were more than three times as likely to have a history of colorectal cancer compared to those without the bacterium.
The findings, published in eGastroenterology, highlight a potential role for gut microbes in accelerating cancer risk in people with a strong genetic predisposition.
Study Details
Between 2018 and 2019, the team studied 75 FAP patients who had not yet undergone colon surgery, preserving their natural gut microbiota. Tissue samples ...
Animal protein not linked to higher mortality risk, study finds
2025-08-22
Hamilton, ON, Aug. 22, 2025–Eating animal-sourced protein foods is not linked to a higher risk of death and may even offer protective benefits against cancer-related mortality, new research finds.
The study, published in Applied Physiology, Nutrition, and Metabolism, analyzed data from nearly 16,000 adults aged 19 and older using the National Health and Nutrition Examination Survey (NHAMES III).
Researchers examined how much animal and plant protein people ...
Satellite insights into eutrophication trends on the Qinghai–Tibet plateau
2025-08-22
This research investigates chlorophyll-a (Chla) variations in lakes across the Qinghai-Tibet Plateau (QTP), a region facing rapid warming. Using Landsat satellite data from 1986 to 2023, the study explores how climate change and human activities, such as grazing and fertilizer use, affect lake water quality. The analysis of 1,069 lakes reveals significant changes in Chla concentrations, indicating increasing eutrophication, particularly in smaller and shallower lakes. The study forecasts future Chla trends until 2100, offering valuable insights for ...
Researchers develop an innovative method for large-scale analysis of metabolites in biological samples
2025-08-22
UNDER EMBARGO UNTIL 10 AM BST / 5 AM ET FRIDAY 22 AUGUST 2025
Researchers develop an innovative method for large-scale analysis of metabolites in biological samples
More images available via the link in the notes section
Researchers from the McCullagh Group in Oxford University’s Department of Chemistry have published an innovative method in Nature Protocols today (22 August) that provides comprehensive analysis of metabolites found in cells, tissues and biofluids.
The new method delivers a step-change in capability for analysing highly polar and ionic metabolites. The innovation comes from using anion-exchange chromatography ...
Asteroid Bennu is a time capsule of materials bearing witness to its origin and transformation over billions of years
2025-08-22
Asteroid Bennu — the target of NASA's OSIRIS-REx sample return mission, led by the University of Arizona — is a mixture of materials from throughout, and even beyond, our solar system. Over the past few billion years, its unique and varied contents have been transformed by interactions with water and the harsh space environment.
These details come from a trio of newly published papers based on analysis of Bennu samples delivered to Earth by OSIRIS-REx in 2023. The OSIRIS-REx sample analysis campaign is coordinated by the U of A's Lunar and Planetary Laboratory (LPL) and involves scientists from around the world. ...
New AI model can help extend life and increase safety of electric vehicle batteries
2025-08-22
Batteries in electric vehicles wear out too quickly and this is slowing down the electrification of the transport sector. Researchers at Uppsala University have now developed an AI model that can provide a much more accurate picture of battery ageing. The model could lead to longer life and enhanced safety for electric vehicle batteries.
It is not uncommon for batteries in electric cars to be the first component of the vehicle to age. This is a major waste of resources today and is holding back the transformation ...
Wildfires can raise local death rate by 67%, shows study on 2023 Hawaiʻi fires
2025-08-22
New research unveils the true death toll of the deadly August 2023 wildfires which took place in Lāhainā, Maui, Hawaiʻi — and which temporarily made wildfire a leading cause of death in Maui. By comparing death rates over time, the scientists found that two-thirds more people died that August than would have been expected. To stop this happening again, the authors say, major policy changes are needed, ranging from removing flammable invasive vegetation to improving disaster preparedness.
“Wildfires can cause a measurable, ...
Yogurt and hot spring bathing show a promising combination for gut health
2025-08-22
Fukuoka, Japan— Researchers at Kyushu University have demonstrated that yogurt intake increases the diversity of gut microbiota and alters its composition. Furthermore, bathing in chloride hot springs after yogurt intake was found to improve defecation status more than yogurt alone. These findings suggest that combining two lifestyle interventions—yogurt intake and hot spring bathing—may contribute to better health, highlighting their potential application for preventive medicine. The study was published in the journal Frontiers in Nutrition.
Maintaining a healthy gut environment ...
Study explains how lymphoma rewires human genome
2025-08-22
Translocations are chromosomal “cut and paste” errors that drive many lymphomas, a type of blood cancer and the sixth most common form of cancer overall. This includes mantle cell lymphoma, a rare but aggressive subtype diagnosed in about one in every 100,000 people each year.
Translocations are known to spark cancer by altering the activity of the genes near the breakpoints where chromosomes snap and rejoin. For example, a translocation can accidentally cut a gene in half, silencing its activity, or create new hybrid proteins ...
New Durham University study counters idea that Jupiter’s mysterious core was formed by a giant impact
2025-08-22
-With images and video-
A new Durham University study has found that a giant impact may not be responsible for the formation of Jupiter's remarkable ‘dilute’ core, challenging a theory about the planet's history.
Jupiter, the largest planet in our solar system, has a mystery at its heart. Unlike what scientists once expected, its core doesn’t have a sharp boundary but instead gradually blends into the surrounding layers of mostly hydrogen (a structure known as a dilute ...
Global study shows racialized, Indigenous communities face higher burden of heart disease made worse by data gaps
2025-08-21
A new study has revealed that racialized and Indigenous communities across Europe, North America, and Central America face significantly higher rates of cardiovascular disease (CVD), and that gaps in health-care data are making the problem worse.
CVD is the leading cause of death worldwide but does not affect people equally. In many countries, Black, South Asian and Indigenous peoples have higher rates of heart disease, diabetes, or high blood pressure compared to white populations. Without an understanding of who is most at risk and why, health systems are unprepared ...
Hemoglobin reimagined: A breakthrough in brain disease treatment
2025-08-21
Did you know the same protein that gives blood its red color and carries oxygen throughout the body is also present inside brain cells? Hemoglobin, long celebrated for ferrying oxygen in red blood cells, has now been revealed to play an overlooked — and potentially game-changing — antioxidant role in the brain.
In neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), Parkinson’s, Alzheimer’s, and aging, brain cells endure relentless damage from the aberrant (or excessive) reactive oxygen species (ROS). For decades, scientists have tried to neutralize ROS with antioxidant ...
Fresh twist to mystery of Jupiter's core
2025-08-21
The mystery at Jupiter's heart has taken a fresh twist – as new research suggests a giant impact may not have been responsible for the formation of its core.
It had been thought that a colossal collision with an early planet containing half of Jupiter's core material could have mixed up the central region of the gas giant, enough to explain its interior today.
But a new study published in Monthly Notices of the Royal Astronomical Society suggests its make-up is actually down to how the growing planet absorbed heavy and light materials as it formed and evolved.
Unlike what scientists ...
Data-driven designs to improve prosthetic legs
2025-08-21
Researchers have developed a new, data-driven way of fitting prosthetic legs which could lead to better fitting prosthetics, in less time and at a lower cost.
The technology has been developed by Radii Devices and the University of Southampton, and the results of an NHS trial have been published today [22 August 2025] in JMIR Rehabilitation and Assistive Technology.
The study shows that below-the-knee prosthetic limbs designed using the new approach were as comfortable on average as those created by highly skilled prosthetists, but with more consistent results. Crucially, the new method generates a basic ...
Under or over? The twists and turns of genetic research
2025-08-21
Under or over? The twists and turns of genetic research
DNA is a molecule that can get twisted and tangled - a process that must be closely regulated
A research team has developed an automated technique to visualise and measure DNA tangles
Technique is so precise it can tell if one DNA segment passes under or over another
At school, it’s often presented as a tidy double helix but scientists are revealing the varied and intricate shapes of DNA molecules.
DNA is a molecule found in just about every living cell. Because the molecule is long, it ends up twisting on itself and getting tangled. Enzymes in the body try to regulate this process but when that ...
Moisture changes the rules of atmospheric traffic jams
2025-08-21
New research from Purdue University reveals how moisture influences atmospheric blocking, a phenomenon that often drives heat waves, droughts, cold outbreaks and floods, helping solve a mystery in climate science and improving future extreme weather predictions.
The study, titled "Blocking Diversity Causes Distinct Roles of Diabatic Heating in the Northern Hemisphere," was published in Nature Communications. Zhaoyu Liu, a PhD student in the Department of Earth, Atmospheric, and Planetary Sciences, and Lei Wang, an assistant professor in ...
Stevens INI advances global Alzheimer’s research with support from the Simon family
2025-08-21
The fourth annual Fork It Alzheimer’s event, hosted by Daryl and Irwin Simon in partnership with the Alzheimer’s Association, took place on July 12, raising funds for groundbreaking Alzheimer’s disease (AD) prevention efforts. During the event, the Simon family announced that the Fork It Fund, created in collaboration with their friend, Stacy Polley, and the Association, awarded $1 million to support a major initiative at the USC Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens ...
New laser “comb” can enable rapid identification of chemicals with extreme precision
2025-08-21
Cambridge, MA – Optical frequency combs are specially designed lasers that act like rulers to accurately and rapidly measure specific frequencies of light. They can be used to detect and identify chemicals and pollutants with extremely high precision.
Frequency combs would be ideal for remote sensors or portable spectrometers because they can enable accurate, real-time monitoring of multiple chemicals without complex moving parts or external equipment.
But developing frequency combs with high enough bandwidth for these applications has been a challenge. ...
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