CNIO research links fertility with immune cells in the brain
The study is published online in Science. It is led by Eva González-Suárez, researcher at the Spanish National Cancer Research Centre.
The team has unexpectedly discovered that cells from the brain defence system play a role in the sexual maturation process. The link between them is RANK, a protein involved in mammary development.
The research has been carried out in animal models, but it has also found genetic mutations associated with a rare syndrome related to infertility in humans.
The kick off signal for puberty begins in the brain. Specifically, in the hypothalamus, where ...