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Polyglycerol coating: A breakthrough in safer nanoparticle environmental remediation

Polyglycerol coating: A breakthrough in safer nanoparticle environmental remediation
2024-05-15
Nanoparticles (NPs) are often used to reduce environmental pollution by targeting harmful chemicals in soil and water that are released by industrial and agricultural activities. These NPs are engineered to absorb, degrade, or neutralize these pollutants, providing a potential solution to environmental contamination. However, when released into the environment, they can be consumed by organisms and transferred through the food chain, resulting in widespread toxicity. To address this issue, a research ...

Circe Bioscience licenses technology to decarbonize industry with microbes developed at Wyss Institute at Harvard University

2024-05-15
The Wyss Institute for Biologically Inspired Engineering at Harvard University announced today that Circe, a startup developed at the Institute and spun out of Harvard, has signed a worldwide, exclusive licensing agreement coordinated by Harvard’s Office of Technology Development (OTD) to commercialize a novel bioproduction technology that could significantly reduce the carbon emissions of industries from food to aviation fuel. Circe has raised more than $8 million to date from investors including Regen Ventures, Undeterred Capital, Ponderosa Ventures, Bee Partners, and Elementum Ventures. “One of the great challenges ...

Parasitic worm likely playing role in decline of moose populations

2024-05-15
PULLMAN, Wash. – A parasitic worm that can infest the brains of moose appears to be playing a role in the decline of the iconic animal in some regions of North America. Moose populations have been dwindling for years across the country due to many contributing factors, but new research at Washington State University has found the impact of Eleaophora schneideri, also known as the arterial worm, has likely been underestimated. Researchers examined recently deceased Shiras moose in Idaho between March 2020 and July 2022. While the parasitic roundworm E. schneideri was not detected in any of the animals found in north Idaho, it was present in 10 of ...

Transcatheter valve replacement outcomes similar to surgery

2024-05-15
A new study demonstrated parity between a minimally invasive procedure to replace the aortic valve in the heart—transcatheter aortic valve replacement (TAVR)—and surgical aortic valve replacement (SAVR). In the meta-analysis of seven randomized trials, published in JSCAI and presented at the 2024 EuroPCR conference in Paris, France, researchers compared the outcomes of 7,785 patients undergoing TAVR (a procedure that delivers a new aortic valve into the heart through a catheter) to those undergoing SAVR for severe aortic stenosis. ...

Germline regulation and sex differences: How they impact lifespan in vertebrates

Germline regulation and sex differences: How they impact lifespan in vertebrates
2024-05-15
The study revealed unexpected and sex-specific effects of germline regulation on longevity and somatic repair in vertebrates. Contrary to classical evolutionary theories, it turns out that changing how the germline (the part responsible for reproduction) works can have different effects on males and females. This challenges conventional beliefs that reproduction and longevity are linked by a limited pool of resources. The research opens up new possibilities for understanding how our bodies age and the role of reproduction in that process. The findings ...

Detection of an Earth-sized exoplanet orbiting the ultracool dwarf star SPECULOOS-3

Detection of an Earth-sized exoplanet orbiting the ultracool dwarf star SPECULOOS-3
2024-05-15
The SPECULOOS project, led by the astronomer Michaël Gillon from the University of Liège, has just discovered a new Earth-sized exoplanet around SPECULOOS-3, an "ultracool dwarf" star as small as Jupiter, twice as cold as our Sun, and located 55 light-years from Earth.  After the famous TRAPPIST-1, SPECULOOS 3 is the second planetary system discovered around this type of star. Ultra-cool dwarf stars are the least massive stars in our Universe, similar in size to Jupiter, more than twice as cold, ten times less massive and a hundred times less ...

Scientists discover blood proteins that may give cancer warning 7 years before diagnosis

2024-05-15
Two Cancer Research UK-funded studies from Oxford Population Health have discovered proteins in the blood that could warn people of cancer more than seven years before it is diagnosed. Scientists identified 618 proteins linked to 19 different types of cancer, including 107 proteins in a group of people who blood was collected at least seven years before diagnosis. The team have discovered that these proteins could be involved at the very earliest stages of cancer, where it could be prevented. They ...

Astronomers discover new Earth-sized world orbiting an ultra-cool star

2024-05-15
A new, Earth-sized planet orbiting an ultra-cool red dwarf star, has been detected by an international team of astronomers – just 55 light years away.  The planet is only the second of its kind to be discovered around this type of star. Called SPECULOOS-3 b, it takes around 17 hours to complete an orbit of the star which is more than twice as cold as our sun, as well as ten times less massive and a hundred times less luminous.  Days and nights on SPECULOOS-3 b seem to be endless: the planet is likely to be tidally locked, so the same side – the ‘dayside’ – always faces the star in a relationship similar to our moon and Earth.    The ...

New biomarker to diagnose Alzheimer's in asymptomatic stages

New biomarker to diagnose Alzheimers in asymptomatic stages
2024-05-15
A recent study led by the Molecular and Cellular Neurobiotechnology group at the Institute for Bioengineering of Catalonia (IBEC) and the University of Barcelona has identified a new biomarker for Alzheimer's disease in asymptomatic stages of the disease. The molecule is miR-519a-3p, a microRNA directly linked to the expression of the cellular prion protein (PrPC), which is deregulated in people suffering from some neurodegenerative diseases such as Alzheimer's. The search for biomarkers that are stable and easily detectable in biofluids, ...

Research sheds light on how proteins linked to Alzheimer’s disease influence neuronal growth

2024-05-15
New research has shed light in the complex interplay between cell proteins, and how they impact on neurons in neurodevelopmental disorders and Alzheimer’s disease. A new study led by the University of Exeter and published in Royal Society Open Biology has discovered the key role that the protein Contactin-4 (encoded by the gene CNTN4) plays in shaping neurons. The researchers began studying CNTN4 because it was known to have a role in autism, but its functional roles were not well understood. The team explored how CNTN4 functions within the brain, particularly its interactions with proteins involved in neurodegenerative diseases like Alzheimer's ...

Early retirement of old vehicles won't save the planet: A study

Early retirement of old vehicles wont save the planet: A study
2024-05-15
Lifespan caps for passenger vehicles have limited effect on reducing greenhouse gas emissions and could drive up costs and material use finds a new study published in Environmental Research: Infrastructure and Sustainability. The research shows that although Light-Duty vehicles (LDVs) contribute 17% to the annual greenhouse gas emissions in the United States, imposing a 15-year lifespan cap on LDV fleets under a business-as-usual scenario will not lead to any meaningful reductions in GHG emissions.  To combat delayed uptake of Electric Vehicles (EVs), some have argued for limits on the vehicle’s ...

EuroPCR 2024 – Short-term data from NOTION-2: TAVR versus SAVI for younger patients with aortic stenosis

2024-05-15
Paris, France, 14-17 May 2024. The Course Directors have selected 3 major Late Breaking Trials (LBTs) that will be presented for the first time during the 2024 edition of EuroPCR. These trials were selected on account of their design, outcomes and potential to influence daily clinical practice.  Among them is the NOTION-2 randomised clinical trial (RCT).  Background   Evidence comparing the use of transcatheter aortic valve implantation (TAVI) and surgical aortic valve replacement (SAVR) in low-risk patients with aortic ...

EuroPCR 2024 – One-month DAPT followed by 5-month Ticagrelor monotherapy in acute coronary syndromes with DCB - results from REC-CAGEFREE II

2024-05-15
Paris, France, 14-17 May 2024. The Course Directors have selected 3 major Late Breaking Trials (LBTs) that will be presented for the first time during the 2024 edition of EuroPCR. These trials were selected on account of their design, outcomes and potential to influence daily clinical practice. Among them is the REC-CAGEFREE II trial.  Background and methods  The REC-CAGEFREE II trial is an open-label, investigator-initiated, non-inferiority, multicentre randomised trial comparing stepwise de-escalation of dual antiplatelet therapy (DAPT) with standard DAPT in patients with acute coronary syndrome (ACS) treated with paclitaxel-coated balloons (PCB). Eligible ...

EuroPCR 2024 – Early outcomes of a randomised non-inferiority trial comparing TAVI devices: the LANDMARK trial

2024-05-15
Paris, France, 14-17 May 2024. The Course Directors have selected 3 major Late Breaking Trials (LBTs) that will be presented for the first time during the 2024 edition of EuroPCR. These trials were selected on account of their design, outcomes and potential to influence daily clinical practice.  Among them is the LANDMARK trial. Background and Methods  Key randomized controlled trials have compared surgical aortic valve replacement (SAVR) with transcatheter aortic valve implantation (TAVI) using one of two commercially available transcatheter heart valves (THVs) - ...

How does exercise benefit the brain?

2024-05-15
New research published in Aging Cell provides insights into how exercise may help to prevent or slow cognitive decline during aging. For the study, investigators assessed the expression of genes in individual cells in the brains of mice. The team found that exercise has a significant impact on gene expression in microglia, the immune cells of the central nervous system that support brain function. Specifically, the group found that exercise reverts the gene expression patterns of aged microglia to patterns seen in young microglia. Treatments that depleted ...

How will climate change affect the distribution of jellyfish and other gelatinous zooplankton in the Arctic Ocean?

2024-05-15
Gelatinous zooplankton, including jellyfish and other diverse, nearly transparent organisms, play important roles in marine ecosystems. Climate change is expected to significantly alter their populations and distributions. New research published in Limnology and Oceanography examines their fate in the Arctic Ocean, one of the fastest warming oceans on Earth. Investigators coupled three-dimensional species distribution models with oceanographic variables from the Coupled Model Intercomparison Project Phase 6. The analyses allowed the team to identify gelatinous ...

Researchers identify new marker for breast cancer prognosis

2024-05-15
A protein called retinitis pigmentosa GTPase regulator interacting protein 1-like (RPGRIP1L) performs various functions that are important for development and for health throughout life, and mutations in the RPGRIP1L gene have been linked to different diseases. New research published in The FASEB Journal indicates that expression levels of the RPGRIP1L gene might serve as a new prognostic marker for individuals with invasive breast cancer. When investigators examined breast tissue specimens from different women, they found that the ...

Can robot-inspired computer-assisted therapy benefit children with autism?

2024-05-15
A new study published in the Journal of Computer Assisted Learning introduces a novel Robot-Inspired Computer-Assisted Adaptive Autism Therapy (RoboCA3T) that leverages the natural affinity of children with autism spectrum disorder towards technology and robots. RoboCA3T harnesses the potential of robot-assisted therapies by incorporating robot avatars and integrating them with computer-assisted therapies through a web-based solution. When investigators assessed Childhood Autism Rating Scale scores before and after the intervention, ...

Does getting out and about in the community affect cognitive function?

2024-05-15
The extent of individuals’ mobility within their community—how much they get out and about—may be linked to their cognitive function, according to new research published in the Journal of the American Geriatrics Society. In the study of 7,016 Black and white adults aged 52 years and older who completed various questionnaires, greater community mobility was significantly associated with better cognitive function, although the association was small. Because higher atherosclerotic cardiovascular disease (ASCVD) risk is associated with both mobility limitations and cognitive decline, investigators ...

How do mindfulness, self-compassion, other-compassion, and need fulfillment affect satisfaction in midlife married couples?

2024-05-15
Many people practice mindfulness or self-compassion techniques in their everyday life as part of their normal self-care routine. Although many studies support the individual benefits of mindfulness and self-compassion, few have focused on romantic relationship outcomes. A new study published in Personal Relationships examined how mindfulness, self- and other-compassion, and need fulfillment relate to relationship and sexual satisfaction in midlife married couples. The study involved survey results from 640 adults aged 40–59 years who were residing in Canada and were married. Mindfulness is the nonjudgmental attention and awareness to present ...

Novel technique helps predict risk of a meniscus tear in the knee

2024-05-15
New research indicates that various features assessed through imaging tests can reveal an individual’s risk of developing meniscus tears, which is one of the most common knee injuries. The study, which is published in the Journal of Orthopaedic Research, was based on the use of radiomics, which unveils imperceptible patterns in medical images. Investigators used magnetic resonance images from 215 people with intact menisci at the start of the study who had 4-year meniscal status data. Over 4 years, 34 participants developed meniscus tears. Use of radiomics at the start of the study correctly classified 24 of these 34 cases and 172 of 181 controls with a sensitivity of 70.6% ...

Healthcare interpreters important for heart attack rehabilitation

Healthcare interpreters important for heart attack rehabilitation
2024-05-15
After a heart attack, foreign-born people are less likely to attend a relapse-preventing Heart School than native-born patients. But with access to a professional interpreter, participation increases. This was found in a study led by researchers at Linköping University, published in the journal IJC Heart & Vasculature. “Our conclusion is that healthcare should always strive to provide professional interpreters. For foreign-born patients, access to interpreters was associated with participation in Heart School, and the education provided there seems to have a similar and positive effect on treatment goals for both foreign-born ...

More women on hospital teams mean better surgery outcomes

2024-05-15
A new paper in the British Journal of Surgery, published by Oxford University Press, finds that care in hospitals with higher surgery team sex-diversity was associated with better post-operative outcomes for patients. In various industries, including business, finance, technology, education, and the law, many observers believe gender and sex-diversity is important not only for equity, but also because it enriches the output of teams because members of the team bring a variety of experiences and viewpoints to their jobs. However, there is limited evidence for the value of teams’ sex-diversity in healthcare. Most published reports have focused on individuals’ ...

Studying bubbles can lead to more efficient biofuel motors

Studying bubbles can lead to more efficient biofuel motors
2024-05-15
By studying how bubbles form in a drop of biodiesel, researchers at the University of Gothenburg can help future engines get the most energy out of the fuel. In an internal combustion engine, the fuel is distributed in small droplets in injection valves to maximise combustion. In the engine, the fuel droplets are pressurised to turn into gas and burn. When gas is formed, bubbles form inside the droplets and it is these that the researchers at the University of Gothenburg have studied using femtosecond lasers. Less emissions “The bubbles have a significant impact on the atomisation of biodiesel in engines. Therefore, our research is very important ...

AACR releases Cancer Disparities Progress Report 2024

2024-05-15
PHILADELPHIA – The American Association for Cancer Research (AACR) today released its Cancer Disparities Progress Report 2024. First published in 2020, this biennial report raises awareness of the enormous toll that cancer exacts on racial and ethnic minority groups and other medically underserved populations in the United States; highlights underlying causes of cancer disparities as well as promising trends in reducing these inequities; and emphasizes the need for continued research and collaborations to ensure that advances against cancer benefit ...
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