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Scientists call for global action on microbial climate solutions

2024-11-11
Washington, D.C. — Nov. 11, 2024 — Today, leaders from scientific societies, institutions and publishing bodies issued an urgent call for the global community and governments to take immediate and decisive emergency climate action. This appeal is made through an editorial published in mSystems, released on the opening day of the 2024 United Nations Climate Change Conference (COP29). Key contributors to this initiative include Virginia Miller, past president of the American Society for Microbiology (ASM); Jack Gilbert, Editor-in-Chief of mSystems; and Jay Lennon, ...

New antibody could be promising cancer treatment

New antibody could be promising cancer treatment
2024-11-11
Researchers at Uppsala University and KTH Royal Institute of Technology have developed a new form of precision medicine, an antibody, with the potential to treat several types of cancer. Researchers have managed to combine three different functions in the antibody, which together strongly amplify the effect of T cells on the cancer tumour. The study has been published in Nature Communications. Researchers have developed a unique type of antibody that both targets and delivers a drug package via the antibody itself, while simultaneously activating the immune system (“3-in-1 design”) for personalised immunotherapy treatments. “We ...

The public implications of private substitutes for electric grid reliability

2024-11-11
Climate change events have, in recent years, placed increasing strain on public electrical grids in the United States. In response to this vulnerability, some consumers are turning to private alternatives to the electric utility, like generators and batteries. A new paper in the Journal of the Association of Environmental and Resource Economists studies who adopts these private alternatives and how adoption responds to grid failures. The paper also studies how public electric grid reliability may change due to this proliferation and how these changes will affect the wellbeing of all households. In ...

Religiosity, spirituality, and meaning-making generally associated with lower suicidality

2024-11-11
November 11, 2024 — All aspects of religiosity, spirituality, and meaning-making (R/S/M) relate to suicidality in people with a psychiatric diagnosis or a recent suicide attempt, according to a systematic review and meta-analysis published in Harvard Review of Psychiatry, part of the Lippincott portfolio from Wolters Kluwer. "Protective dimensions seemed to exert relatively stable effects across different religions and life views," Bart van den Brink, MD, PhD, of the Department of ...

Eife studying legal surveillance as social determinant of health

2024-11-11
Erin Eife, Assistant Professor, Criminology, Law and Society, College of Humanities and Social Sciences (CHSS), received funding for the project: “Surveillance as a Social Determinant of Health: Understanding the Impact of Pending Charges on Health Outcomes.” Eife will conduct this research under the advisement of Evan Lowder, Associate Professor, Criminology, Law and Society, College of Humanities and Social Sciences (CHSS), and Lauren Brinkley-Rubinstein, Associate Professor in the Department of Population Health Sciences at Duke University. Eife aims to produce knowledge about ...

Newly developed 100Gbps data transfer system for accelerating Open Science through industry-university collaboration in Japan

Newly developed 100Gbps data transfer system  for accelerating Open Science through industry-university collaboration in Japan
2024-11-11
Tokyo & Osaka, Japan – Osaka University and NEC Corporation (NEC; TSE: 6701) are moving forward with efforts to realize a data infrastructure supporting Open Science. In 2021, The Joint Research Laboratory for Integrated Infrastructure of High Performance Computing and Data Analysis was established within the D3 Center, Osaka University (Director: Professor Susumu Date*1) by Osaka University and NEC. The result of the Joint Research Laboratory will be showcased at the International Conference for High Performance Computing, Networking, Storage, and Analysis (SC24) scheduled ...

Navigating bias in AI-driven cancer detection

Navigating bias in AI-driven cancer detection
2024-11-11
“As we eagerly adopt Al models, we need to take a moment to think about the potential biases that they may contain.” BUFFALO, NY - November 11, 2024 – A new editorial was published in Oncotarget's Volume 15 on November 7, 2024, titled “ Beyond the hype: Navigating bias in AI-driven cancer detection.” In this editorial, researchers from the Mayo Clinic emphasize the need to address potential biases in Artificial Intelligence (AI) tools used for cancer detection to ensure fair and equitable healthcare. Authors Yashbir Singh, Heenaben Patel, Diana V. Vera-Garcia, Quincy A. Hathaway, ...

Research shows stress about personal finances may make leaders abusive in workplace

Research shows stress about personal finances may make leaders abusive in workplace
2024-11-11
New research from Colorado State University shows that workplace leaders who are financially stressed are more likely to be abusive toward their subordinates – particularly if the leader is a man.  The findings, published in the Journal of Occupational Health Psychology, provide insight into leader behavior due to a common source of stress. The research was led by Assistant Professor Keaton Fletcher in the Department of Psychology in partnership with Associate Professor Trevor Spoelma in the Anderson School of Management at the University ...

Holistic approach of nutrients and traditional natural medicines for human health

2024-11-11
In recent years, there has been a rising interest in combining traditional natural medicines with essential nutrients to foster a holistic approach to human health. The focus on integrating both elements reflects an understanding of health that transcends the simple absence of disease, encompassing physical, mental, and spiritual well-being. This review highlights how traditional medicine systems, such as Ayurveda, Traditional Chinese Medicine (TCM), and other indigenous practices worldwide, can be harmonized with nutritional science to form a comprehensive healthcare approach. Such a combination has the potential to improve disease prevention and enhance overall ...

Study: Online E-cigarette retailers fail to comply with sale regulations

Study: Online E-cigarette retailers fail to comply with sale regulations
2024-11-11
Online e-cigarette retailers are not consistently adhering to laws aimed at preventing the sale of vaping products to minors, including regulations on age verification, shipping methods and flavor restrictions, report researchers at the Herbert Wertheim School of Public Health and Human Longevity Science at University of California San Diego. In a study published online on Nov. 11, 2024 in JAMA, researchers asked 16 people to purchase flavored vape products online and have them delivered to their homes in the County of San Diego, ...

Prevalence of adverse childhood experiences in child population samples

2024-11-11
About The Study: In this study, adverse childhood experiences (ACEs), which include abuse, neglect, and family dysfunction, were prevalent among children with notable disparities across participant demographic characteristics and contexts. As principal antecedent threats to child and adolescent well-being that can affect later life prospects, ACEs represent a pressing global social issue. Effective early identification and prevention strategies, including targeted co-designed community interventions, can reduce the prevalence of ACEs and mitigate their severe effects, thereby minimizing the harmful health consequences of childhood adversity in future generations. Corresponding ...

Asthma and memory function in children

2024-11-11
About The Study: In this cohort study, asthma was associated with memory difficulties in children, which may be more severe if asthma onset is earlier in childhood and may extend to executive function abilities.  Corresponding Author: To contact the corresponding author, Nicholas J. Christopher-Hayes, MA, email nchristopherhayes@ucdavis.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2024.42803) Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of ...

Asthma may place children at risk of memory difficulties, new research finds

2024-11-11
Asthma is associated with memory difficulties in children, and early onset of asthma may exacerbate memory deficits, according to a new study from the University of California, Davis. The study, the first of its kind to connect asthma to memory deficits in children, was published in Nov. 5 in JAMA Network Open. “This study underscores the importance of looking at asthma as a potential source of cognitive difficulty in children. We are becoming increasingly aware that chronic diseases, not only asthma but also diabetes, heart disease and others may place children at increased risk of cognitive difficulties,” said lead author Simona Ghetti, a professor of psychology ...

Age related health decline a predictor of future dementia risk

2024-11-11
An international study led by a University of Queensland researcher has found frailty increases a person’s risk of dementia, but early intervention may be the key to prevention. Dr David Ward from the Centre for Health Services Research tracked the data of nearly 30,000 participants of 4 longitudinal studies in the United Kingdom and the United States, enabling researchers to detect changes in people’s health and function 20 years before they were diagnosed with dementia. “The accumulation of age-related conditions is indicative of increasing frailty, which we found accelerates up to 9 years prior to a dementia diagnosis,” Dr Ward said. “Our ...

First-in-human universal gene therapy for blood disorder

2024-11-11
Diamond-Blackfan anemia (DBA) is potentially life-threatening condition that can cause severe anemia and other abnormalities. It’s a rare genetic blood disorder that occurs when the bone marrow fails to make red blood cells. Currently the only cure is a stem cell transplant, but this is only a viable option for select patients. Otherwise, children with DBA require lifelong follow-up care to manage symptoms, such as steroids and blood transfusions. New data publishing 11/11 in Cell Stem Cell provides strong support for the first-in-human universal gene therapy trial for DBA through regulated GATA1 expression. Notably, it’s ...

Study: Older adult prostate cancer patients are increasingly being overtreated

2024-11-11
Increasing percentages of some older U.S. men with intermediate-risk and high-risk prostate cancers are undergoing treatments that carry risks of side effects that can significantly reduce the quality of life without extending life, according to a new study led by Cedars-Sinai. This trend is problematic because these men may not have life expectancies that would allow them to receive the benefits of more aggressive treatments. The research findings were published in the peer-reviewed journal JAMA Internal Medicine. Prostate cancer is the second-most common cancer in the U.S., exceeded ...

Experiences of discrimination linked to postpartum weight retention

2024-11-11
PITTSBURGH, November 11, 2024 – Researchers have been unable to explain why after giving birth, Black patients are two to three times as likely to retain or gain additional weight compared to their white counterparts, even when pre-pregnancy weight and gestational-weight trajectories are comparable. A first-of-its-kind study by University of Pittsburgh epidemiologists points to the stress of lived experiences with racism and gender-based discrimination as a possible explanation. The study was reported today in the American Journal of Epidemiology. Since postpartum weight retention is associated with increased cardiovascular risk and other negative health outcomes that persist ...

New python package, ERTool, developed for efficient multi-source evidence fusion

New python package, ERTool, developed for efficient multi-source evidence fusion
2024-11-11
Researchers from Peking University have developed ERTool, an open-source Python package designed to simplify the implementation of the Evidential Reasoning (ER) approach for multi-source evidence fusion. This tool addresses the challenges of integrating data from multiple sources in uncertain decision-making environments. The results are published in Health Data Science. Multi-source evidence fusion plays a critical role in fields such as healthcare management, business analytics, and environmental risk assessment. However, the traditional application of the ER approach has been complicated, requiring expertise in coding. To overcome these challenges, Associate Research Professor Guilan ...

AI-based software 'guide' childbirth by ‘seeing’ the baby’s position in real time

2024-11-11
A new AI-based software has been developed that can be integrated with an ultrasound device to ‘guide’ childbirth by providing precise, real-time information on the baby’s head position. It can clearly indicate to operators—using a traffic light system—whether to proceed with a natural descent in the birth canal, whether to use a vacuum extractor, or even if an emergency cesarean is needed.   This tool, which could be available in delivery rooms starting in 2028, was developed and validated as part of a ...

Arab scholars from around the globe convene in Qatar to advance science and research

Arab scholars from around the globe convene in Qatar to advance science and research
2024-11-11
Doha, November 11, 2024 – The Arab Global Scholars (AGS) community gathered at Hamad Bin Khalifa University (HBKU) in Qatar Foundation’s Education City last week to herald the latest evolution of an initiative nurturing a contemporary renaissance of Arab science and research. An initiative led by Qatar Foundation, AGS aims to reconnect scholars and intellectuals with roots in the Arab world back to their region to contribute to its positive development and long-term future. Its beginnings going back almost two decades, AGS has solidified itself as an innovation-focused community linking 895 Arab scholars, as well as research ...

Gender inequality ingrained in global climate negotiations, say researchers

2024-11-11
Climate governance is dominated by men, yet the health impacts of the climate crisis often affect women, girls, and gender-diverse people disproportionately, argue researchers ahead of the upcoming 29th United Nations Climate Summit (COP29) in Azerbaijan. In an article published today in Lancet Planetary Health, a team of researchers – including several from the University of Cambridge – argue that much more needs to be done to mitigate the impacts of climate change on women, girls and gender-diverse individuals. Focusing specifically on the intersection between climate change, gender, and human health, ...

There's no time like the present for integrating climate and violence policies: The opportunity is right

2024-11-11
The dual goals of climate action and ending violence against children can be achieved according to a new paper by Columbia University Mailman School of Public Health and colleagues at the London School of Hygiene and Tropical Medicine. For the first time, governments are committing funds and making concrete pledges to reach the UN Sustainable Development Goal target of ending violence against children. On November 7th and 8th, the Government of Colombia, with support of the Government of Sweden, UNICEF, the UN Special Representative of the Secretary-General on Violence Against Children, and the World Health Organization will attend the first Global Ministerial Conference on ending ...

Breaking free from negative thoughts using a scientifically gamified app

Breaking free from negative thoughts using a scientifically gamified app
2024-11-11
(Toronto, November 11, 2024) A new study published in the Journal of Medical Internet Research by JMIR Publications reveals promising results from a digital health intervention that is based on a decade of research at Harvard Medical School and designed to alleviate depressive symptoms. The study, titled "Facilitating Thought Progression to Reduce Depressive Symptoms: Randomized Controlled Trial," found that participants experienced substantial reduction of depressive symptoms by using a gamified mobile app focused on disrupting ruminative thinking. Led by Prof. Moshe Bar and colleagues, the research ...

The emerging role of (p)ppGpp in DNA repair and associated bacterial survival against fluoroquinolones

The emerging role of (p)ppGpp in DNA repair and associated bacterial survival against fluoroquinolones
2024-11-11
Bacteria frequently encounter adverse environmental conditions, such as nutrient scarcity and antibiotic exposure, which can induce DNA damage. Efficient DNA repair mechanisms are essential for bacterial survival, particularly under such stress conditions. A critical player in these processes is the signaling molecule (p)ppGpp, a phosphorylated guanosine synthesized by bacteria during periods of stress. Initially discovered in Escherichia coli under amino acid starvation, (p)ppGpp is now recognized for its broader roles in modulating cellular functions essential for DNA repair and stress response. By regulating diverse cellular processes, (p)ppGpp not ...

People with fewer resources seen as less trustworthy across cultures, new research shows

2024-11-11
New research in Social Psychological and Personality Science identifies a widespread stereotype linking wealth to perceived trustworthiness across diverse cultures. The research, led by Mélusine Boon-Falleur from the Center for Research on Social Inequalities at Sciences Po in Paris, shows that individuals with fewer material resources are consistently viewed as less trustworthy. The study, conducted across eight countries including Brazil, Colombia, Democratic Republic of Congo, India, France, Nigeria, Philippines, and the United Kingdom, employed a novel method to uncover stereotypes while avoiding social desirability bias. "People ...
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