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Simple blood test could predict risk of long-term COVID-19 lung problems

Simple blood test could predict risk of long-term COVID-19 lung problems
2024-03-15
UVA Health researchers have discovered a potential way to predict which patients with severe COVID-19 are likely to recover well and which are likely to suffer “long-haul” lung problems. That finding could help doctors better personalize treatments for individual patients. UVA’s new research also alleviates concerns that severe COVID-19 could trigger relentless, ongoing lung scarring akin to the chronic lung disease known as idiopathic pulmonary fibrosis, the researchers report. That type of continuing lung damage would mean that patients’ ability to breathe would continue to worsen over time. “We are excited ...

Study of fatal and nonfatal shootings by police reveals racial disparities, dispatch risks

2024-03-15
A new study from researchers at the Johns Hopkins Center for Gun Violence Solutions and Vanderbilt University found that an average of 1,769 people were injured annually in police shootings from 2015 to 2020, 55 percent of them or 979 people, fatally. The study covered a total of 10,308 incidents involving shootings by police. The Center is based at the Johns Hopkins Bloomberg School of Public Health. The majority of victims in shootings by police—84 percent overall—were reported as armed with a firearm or other weapon, such as a knife or vehicle, during ...

New study reveals COVID-19 may have originated in a lab

2024-03-15
The origin of COVID-19 is highly debated – most studies have focused on a zoonotic origin, but research from the journal Risk Analysis, examined the likelihood of an unnatural origin (i.e. from a laboratory.) The results indicate a greater likelihood of an unnatural than natural origin of the virus. The researchers used an established risk analysis tool for differentiating natural and unnatural epidemics, the modified Grunow-Finke assessment tool (mGFT) to study the origin of COVID-19. This risk assessment cannot prove the specific origin of COVID-19 but shows that the possibility of a laboratory origin ...

Not just a lodger: Novel host-guest assembly provides enhanced reactivity

Not just a lodger: Novel host-guest assembly provides enhanced reactivity
2024-03-15
By design, synthetic molecules typically have specific jobs to prevent or accelerate reactions between other molecules. To help control more complicated reactions, researchers may harness spare space in one molecule to synthesize another chemical structure. The host-guest assembly can better induce the specific desired reaction than either component individually — if the scientists designing the assembly get it right.   A multi-institution team based in China has reported a novel cluster — the guest — that nucleated ...

Revolutionary method developed for mass-producing polymer solid electrolytes

Revolutionary method developed for mass-producing polymer solid electrolytes
2024-03-15
A research team, led by Professor Seok Ju Kang in the School of Energy and Chemical Engineering at UNIST, has unveiled a groundbreaking technique for mass-producing polymer solid electrolytes, crucial components in batteries. Departing from the traditional melt casting method, the team introduced a horizontal centrifugal casting method to overcome existing limitations. This innovative approach has redefined the production process for high-quality polymer solid electrolytes, revolutionizing the industry. Drawing inspiration from the horizontal centrifugal casting technique used in producing iron pipes, the research team successfully achieved a uniform polymer ...

What a view: Rice scientists develop a new system to record 2D crystal synthesis in real time

What a view: Rice scientists develop a new system to record 2D crystal synthesis in real time
2024-03-15
HOUSTON – (March 15, 2024) – Materials scientists at Rice University are shedding light on the intricate growth processes of 2D crystals, paving the way for controlled synthesis of these materials with unprecedented precision. Two-dimensional materials such as graphene and molybdenum disulfide (MoS2) exhibit unique properties that hold immense promise for applications in electronics, sensors, energy storage, biomedicine and more. However, their complex growth mechanisms — inconsistent correlations ...

New study reveals breakthrough in understanding brain stimulation therapies

New study reveals breakthrough in understanding brain stimulation therapies
2024-03-15
MINNEAPOLIS/ST. PAUL (03/15/2024) — For the first time, researchers at the University of Minnesota Twin Cities showed that non-invasive brain stimulation can change a specific brain mechanism that is directly related to human behavior. This is a major step forward for discovering new therapies to treat  brain disorders such as schizophrenia, depression, Alzheimer’s disease, and Parkinson’s disease. The study was recently published in Nature Communications, a peer-reviewed, open ...

Abnormal brain structure identified in children with developmental language problems

2024-03-15
WASHINGTON – A rigorous analysis of numerous studies concludes that a part of the brain traditionally associated with movement is abnormal in children with developmental language impairments, according to Georgetown University Medical Center neuroscientists. The discovery has the potential to improve both the diagnosis and treatment of the language difficulties. The researchers investigated brain abnormalities in developmental language disorder. This condition, which impacts the development of various aspects of language, is about as common as attention-deficit/hyperactivity ...

DNA origami-based vaccines toward safe and highly-effective precision cancer immunotherapy

DNA origami-based vaccines toward safe and highly-effective precision cancer immunotherapy
2024-03-15
By Benjamin Boettner  (BOSTON) — Therapeutic cancer vaccines are a form of immunotherapy in the making that could not only destroy cancer cells in patients, but keep a cancer from coming back and spreading. Multiple therapeutic cancer vaccines are being studied in clinical trials, but despite their promise, they are not routinely used yet by clinical oncologists to treat their patients.  The central ingredient of therapeutic cancer vaccines is antigens, which are preferentially produced or newly produced (neoantigens) by tumor cells and enable a patient’s immune system to search and destroy the cancerous ...

Printed polymer allows researchers to explore chirality and spin interactions at room temperature

2024-03-15
A printable organic polymer that assembles into chiral structures when printed has enabled researchers to reliably measure the amount of charge produced in spin-to-charge conversion within a spintronic material at room temperature. The polymer’s tunable qualities and versatility make it desirable not only for less expensive, environmentally friendly, printable electronic applications, but also for use in understanding chirality and spin interactions more generally.  Spintronic devices are electronic devices that harness the spin of an electron, ...

Special section of The Permanente Journal focuses on how early-life trauma correlates to poor health outcomes

2024-03-15
For Immediate Release OAKLAND, Calif., March 15, 2024 — Innovation in trauma-informed health care is the core focus of a special section in today’s issue of The Permanente Journal. The special section features 13 articles that touch on this increasingly prominent approach and reaches into several diverse subdomains such as mental health, physical health, body size diversity and systems-level implementation. Workplace wellness, clinician training and medical school curricula related to trauma are also covered in the issue. Trauma-informed health care has grown ...

New insights could improve treatment of liver fibrosis

New insights could improve treatment of liver fibrosis
2024-03-15
The liver is not only the largest internal organ but also vital for human life as a metabolic center. It also possesses remarkable self-healing powers: even when large portions are removed, such as during surgery, they quickly regenerate in healthy individuals. However, in cases of repeated or chronic injury to the liver tissue, as caused by excessive alcohol consumption or viral hepatitis, this regenerative capacity fails. Scarring occurs, known as fibrosis, where liver cells are replaced by fibrous tissue. The liver hardens and becomes increasingly unable to perform its functions - in the worst case, this leads to liver failure. To ...

Women involved in car crashes may be more likely to go into shock than men

2024-03-15
It is well known that car safety equipment was originally designed with male-representative bodies in mind. This means women sitting in the front row are more likely to suffer severe or fatal injuries in the case of a crash. They are also more likely to be trapped in crashed cars. Interested in the inequalities of car design and the resulting injuries, a team of researchers in the US has used trauma injury data from car crash victims to evaluate differences in injury patterns typical for males and females. “We found that vehicle crash injury patterns and injury severity differ between men and women. We also show that women are arriving ...

Researchers attempt to clarify correlation between strain and catalytic activities for 2D catalysts

2024-03-15
Researchers led by Prof. WANG Bin at National Center for Nanoscience and Technology (NCNST) of the Chinese Academy of Sciences recently reported that strain generated at bubbles of 2D materials can benefit the catalytic activity of the hydrogen evolution reaction (HER). The study was published in Chem Catalysis.  Green hydrogen produced by electrochemical water splitting offers the potential to achieve carbon-neutral production processes. Catalysts play a crucial role in facilitating HER at the anode, making it a key component in the transition to a sustainable energy future. Transition metal dichalcogenides (TMDs), particularly MoS2, have drawn attention ...

A theory linking ignition with flame provides roadmap to better combustion engines

A theory linking ignition with flame provides roadmap to better combustion engines
2024-03-15
In a study published on January 18, 2024 in the journal Physics of Fluids, researchers from Tohoku University theoretically linked ignition and deflagration in a combustion system, unlocking new configurations for stable, efficient combustion engines due to the possible existence of any number of steady-state solutions. "This research directly tackles the challenge of reducing carbon dioxide emissions by enhancing the efficiency of combustion engines, a significant source of these emissions," said Youhi Morii from the ...

Doping engineering in halide perovskite, an efficient synthesis method of white LEDs

Doping engineering in halide perovskite, an efficient synthesis method of white LEDs
2024-03-15
In 1879, Edison invented the incandescent lamp, which brought light to the night. In 1969, the first red light emitting diodes (LEDs) lamp came out. However, as the key to making white light bulbs, high-energy blue light has not been successfully commercialized. Until 1998, the Japan’s Nakamura Shoji made white LEDs, which marked the official entry of LEDs into the lighting era. LEDs have the advantages of high efficiency, environmental protection and energy saving. Metal halide perovskites (MHPs) have become a powerful candidate for new LEDs ...

Parallel physical random bit generation towards rates of order 100 Tb/s

Parallel physical random bit generation towards rates of order 100 Tb/s
2024-03-15
In our digital networked society, random bit generators (RBGs) are vital for services and state-of-the-art technologies such as cryptographically secured communication, blockchain technologies, and quantum key distribution. An ever-increasing demand to improve the security of digital information has shifted the generation of random bits from sole reliance on pseudorandom algorithms to the use of physical entropy sources. Shannon’s theorem establishes that it is required for the ultimate security to achieve bit rate matching that of the true RBGs with that of the communication systems. For this purpose, optical chaos has been widely studied in the past decades as a means for the ...

The Lancet Neurology: Neurological conditions now leading cause of ill health and disability globally, affecting 3.4 billion people worldwide

2024-03-15
Peer-reviewed / Modelling study / People Embargoed access to the paper and contact details for authors are available in Notes to Editors at the end of the release. Most comprehensive study to date finds the burden of nervous system (neurological) conditions is much greater than previously understood, with this diverse group of conditions affecting 43% of the world’s population (3.4 billion individuals) in 2021. Neurological conditions were responsible for 443 million years of healthy life lost due to illness, disability, and premature death (disability-adjusted life years) in 2021, making them the ...

Study of long-term student engagement challenges “one great teacher” narrative of education

2024-03-15
A positive relationship with a teacher at an early age may help children to feel more engaged with school, but not necessarily in the long term, new research shows. The finding comes from a University of Cambridge study of more than 3,600 young people in Australia, using data gathered at several points between the ages of eight and 15. The students’ levels of school engagement – meaning their interest in school and willingness to learn – fluctuated during this period, especially during the ...

UChicago Medicine helps bring first-of-its-kind drug for metabolic liver disease to the clinic

2024-03-15
Liver disease specialists at the University of Chicago Medicine will soon begin prescribing a first-of-its-kind drug for treating advanced metabolic dysfunction-associated steatotic liver disease (MASLD) — formerly known as nonalcoholic fatty liver disease (NAFLD). Resmetirom (to be sold under the brand name Rezdiffra), received FDA approval on March 14, 2024. It is the first medication approved for treating metabolic dysfunction-associated steatohepatitis (MASH), a more advanced stage of MASLD characterized by liver inflammation and scarring known as fibrosis. “Until now, liver disease has ...

Long COVID ‘indistinguishable’ from other post-viral syndromes a year after infection

2024-03-14
**Note: the release below is a special early release from the European Congress of Clinical Microbiology and Infectious Diseases (ECCMID 2024, Barcelona, Spain, 27-30 April). Please credit the congress if you use this story** Long COVID appears to manifest as a post-viral syndrome indistinguishable from seasonal influenza and other respiratory illnesses, with no evidence of increased moderate-to-severe functional limitations a year after infection, according to new research being presented at this year’s European Congress of Clinical Microbiology and Infectious Diseases (ECCMID 2024) in ...

Improved neuromonitoring could prevent brain injuries for patients on ECMO life support

Improved neuromonitoring could prevent brain injuries for patients on ECMO life support
2024-03-14
Extracorporeal membrane oxygenation (ECMO) can be a life-saving therapy for patients with acute heart or lung failure. During ECMO therapy, a patient’s blood flows out of their veins through tubes and into a machine that does both the actions of the heart and lungs. The oxygenated blood is then returned to the body allowing the heart and lungs to rest. While ECMO can stabilize a critically ill patient in an intensive care unit, the procedure carries significant risks, including brain injury. Often these patients are comatose, and current neuromonitoring techniques are too risky and invasive to perform routinely. Now, researchers at the University ...

Kurdish uprisings have led to new ways for communities to claim Kurdish identity, study shows

2024-03-14
Kurdish uprisings have become a way for people to assert their identity and challenge their historical and structural erasure in modern Iran, a new study shows. Protests following the death of Jina (Mahsa) Amini in police custody in Iran led to “remarkable” acts of resistance built on decades of activism, according to the research. The study, published in the International Journal of Middle East Studies, outlines how the growing resistance that up to “Jîna's uprising” had been largely unnoticed by many Iranians. Dr ...

Infections from these bacteria are on the rise. New blood test cuts diagnosis time from months to hours

2024-03-14
Inhaling nontuberculous mycobacteria is common for most people. The bacteria are found in water systems, soil and dust worldwide and, for many, cause no harm. For those with underlying conditions, nontuberculous mycobacteria (NTM) can infect the lungs, causing symptoms similar to tuberculosis. Inflammation can cause a chronic and sometimes bloody cough as well as scarring, which can make respiratory infections like bronchitis and pneumonia more common. Due to the slow growth of the bacteria, proper diagnosis and treatment can take months. In a new study, Tulane University researchers have developed a CRISPR-based platform for diagnosing NTM infections where blood testing ...

Researchers prove fundamental limits of electromagnetic energy absorption

2024-03-14
Electrical engineers at Duke University have determined the theoretical fundamental limit for how much electromagnetic energy a transparent material with a given thickness can absorb. The finding will help engineers optimize devices designed to block certain frequencies of radiation while allowing others to pass through, for applications such as stealth or wireless communications. “Much of the physics of the known universe already have fundamental solutions or are too complex to get an exact answer,” said Willie Padilla, professor of electrical and computer engineering at Duke. “In any field, finding a truly novel, fundamental, exact ...
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