Embargo 16 September 2025 at 17:00 UK time / 12:00 US ET Peer-reviewed / Human cell lines / Experimental KIDNEY TRANSPLANT REJECTION ASSOCIATED WITH CHANGES IN LYMPHATIC VESSELS, NEW RESEARCH SHOWS Scientists have uncovered how lymphatic vessels – the kidney’s ‘plumbing system’ – undergo dramatic changes during chronic transplant rejection, becoming structurally disorganised and spreading to unusual parts of the kidney. Researchers at the Wellcome Sanger Institute, University College London (UCL) and the University of Cambridge used single-cell sequencing combined with powerful 3D imaging to look at small lymphatic vessels in kidney tissue, comparing healthy ...

EWRR is recognised as a friendly and interactive forum for basic and translational researchers working in rheumatology. The initial meeting took place in 1981, and four decades later it is still providing up-to-date information – helping to unpick the basic mechanisms of rheumatic and musculoskeletal diseases (RMDs), and supporting the development of advanced treatment options. Considered Europe’s premier event for basic and translational research in the field of rheumatology, its core aim is to attract young scientists and to give them ...

Researchers at the German Center for Infection Research (DZIF) at Heidelberg University Hospital have decoded a previously unknown mechanism by which HIV-1 selects its integration targets in the human genome. A research team led by DZIF scientist Dr. Marina Lusic identified RNA:DNA hybrids (R-loops) as molecular signposts for the virus. These findings reveal a key vulnerability in the life cycle of HIV-1. The results, published in the renowned journal Nature Microbiology, provide new therapeutic approaches for specifically controlling HIV reservoirs in the body. This has been one of the biggest obstacles to long-term or curative HIV therapies. Thanks ...

Fukuoka, Japan—For most people, swallowing is second nature, but how does it occur, and why do some people have difficulty with it? Researchers at Kyushu University in Japan have started to tackle these questions by developing a mathematical model that recreates the muscle movements of the esophagus that occur during swallowing. The model, reported in Royal Society Open Science, also replicates muscle dynamics seen in various esophageal motility disorders, revealing insights into their underlying causes and opening up new avenues for treatment. A ...

A growing body of research ties environmental pollutants to worse health and shorter life spans for childhood cancer survivors. Yet medical providers lack sufficient resources to address these risks with patients, a recent federally funded study found. The study, published in Cancers, revealed 80% of pediatric oncology providers surveyed received questions from families about the impact of environmental pollutants on children’s health, but only 25% of providers said they felt comfortable discussing the topic. “Medical providers receive little to no education or clinical training on the impacts of environmental pollutants like pesticides and wildfire smoke ...

Research led by the Transforming and Expanding Access to Mental Health Care Universally in Pediatrics (TEAM UP) Scaling and Sustainability Center of Boston Medical Center (BMC) finds that children who receive behavioral health services delivered through the TEAM UP Model™ of integrated behavioral health care have fewer behavioral health symptoms.  The findings, published recently in JAMA Network Open, offer new hope for addressing the children’s mental health crisis.    “Several prior studies demonstrate that TEAM UP ...

WASHINGTON, Sept. 16, 2025 – Over 200 underwater bridge tunnels exist for vehicular traffic around the world, providing connectivity between cities. Once constructed, however, these tunnels are difficult to monitor and maintain, often requiring shutdowns or invasive methods that pose structural risks. Muography — an imaging technique using high-energy particles, called muons, which can traverse hundreds of meters within the earth — can provide a noninvasive approach to examining subterranean infrastructure. In the Journal of Applied Physics, by AIP Publishing, ...

WASHINGTON, Sept. 16, 2025 – Everyone hates traffic. Big cities in particular are plagued by an overabundance of vehicles, turning a simple crosstown jaunt into an odyssey during rush hour. Part of the problem is that traffic is incredibly complex, and a small change in one part of the system can have ripple effects that alter traffic patterns throughout a city. City planners attempting to improve local traffic grids can often struggle to foresee all the effects their changes could have. In Chaos, by AIP Publishing, a pair of ...

About The Study: In this cohort study of children at federally qualified health centers implementing behavioral health integration, receipt of encounters with behavioral health clinicians and psychotropic prescriptions were associated with improved psychosocial symptoms, suggesting that expanding integrated pediatric behavioral health care might enhance behavioral health outcomes among marginalized pediatric populations. Corresponding author: To contact the corresponding author, R. Christopher Sheldrick, Ph.D., email radley.sheldrick@umassmed.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi: ...

About The Study: In this cross-sectional study, uterine fibroid embolization was underutilized with significant disparities across socioeconomic factors. Further efforts are needed to equitably expand access to uterine fibroid embolization across the country. Corresponding author: To contact the corresponding author, Tarig S. Elhakim, M.D., M.P.H., email tarigelhakim@gmail.com. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi: 10.1001/jamanetworkopen.2025.32100) Editor’s ...

Orange, Calif. — Sept. 16, 2025 — A new study led by the U.S. Forest Service, with Chapman University as a key senior collaborator, published in Nature Communications, suggests the Earth’s own tropical soils may contribute to climate change as global warming continues, releasing vast amounts of carbon dioxide (CO₂) as they warm and potentially accelerating a dangerous feedback loop. Tropical forests have long been viewed as critical allies in the fight against climate change, natural systems that absorb excess carbon and cool the planet. But this new research shows that warming itself is causing ...

“We believe that our findings will incentivize further studies to identify the best disease-modifying therapy for early PD without dementia.” BUFFALO, NY — September 16, 2025 — A new research paper was published  in Volume 17, Issue 8 of Aging-US on August 6, 2025, titled “Age-related trends in amyloid positivity in Parkinson’s disease without dementia.” In this study, led by first author Keiko Hatano and corresponding author Masashi Kameyama from the Tokyo Metropolitan Institute for Geriatrics and Gerontology in Japan, researchers ...

OAK BROOK, Ill. – An artificial intelligence (AI) deep learning tool that estimates the malignancy risk of lung nodules achieved high cancer detection rates while significantly reducing false-positive results. Results of the study, which used data from large, multi-site lung cancer screening trials, were published today in Radiology, a journal of the Radiological Society of North America (RSNA).   Lung cancer remains a significant global health issue, causing the most cancer-related deaths worldwide. Screening high-risk individuals with low-dose chest CT has been shown to reduce lung cancer mortality. However, early screening trials have reported high false-positive rates, leading ...

ITHACA, NY—A new study published today in the journal Biological Conservation finds that different communication approaches can influence whether people take action to prevent birds from colliding with windows, a leading cause of bird mortality that kills over 1 billion birds annually in the United States and Canada. Researchers from the Cornell Lab of Ornithology tested different message framing approaches among bird enthusiasts and the general public to understand what motivates people to make their windows safer for birds. “If we want people to take action to reduce bird and window collisions, we really have to understand how to communicate with ...

SAN ANTONIO — September 16, 2025 — Southwest Research Institute (SwRI) and The University of Texas at San Antonio (UT San Antonio) are collaborating to create a detection system to identify pre-ignition in hydrogen internal combustion engines (H2-ICE). Researchers will combine machine learning (ML) algorithms and artificial intelligence with onboard sensors to help detect pre-ignitions based on their tell-tale signs. Pre-ignition occurs when unprompted combustion happens inside an engine before the prescribed spark timing. These abnormal, uncontrolled ...

Ammonia is used in fertilizer and many industrial processes. It is also seen as a promising way to store and transport energy, as it is safer and easier to handle ammonia than hydrogen gas. Using plasma, the fourth state of matter, scientists have created a material that boosts ammonia production.  “If one needs industrial hydrogen someplace else than where it is made, it will be easier and safer to transport hydrogen as ammonia and store it until it is needed. Ideally then one would decompose the ...

The International Data Corporation projects that artificial intelligence will add $19.9 trillion to the global economy by 2030, yet educators are still defining how students should learn to use the technology responsibly. To better equip AI educators and to foster a sense of community among those in the field, Kennesaw State University Department Chair and Professor of Information Technology (IT) Shaoen Wu, along with assistant professors Seyedamin Pouriyeh and Chloe “Yixin” Xie, were recently awarded two National Science Foundation ...

Cardiac arrest happens when the heart stops pumping blood properly, cutting off oxygen to the brain and other vital organs. In these emergencies, cardiopulmonary resuscitation (CPR) can help keep blood and oxygen moving until medical help arrives. For children, CPR usually needs both chest compressions and rescue breaths, because many cases are caused by breathing problems such as drowning, choking, or serious illness. During the COVID-19 pandemic, fear of infection changed the way CPR was practiced. Public health guidelines for adults recommended chest compression-only CPR (CO-CPR) to minimize the risk of ...

In markets where producers drive the creative process, high-status producers can opt for more radical changes for their artists’ image, whereas middle-status producers are likely to shift their artists’ image to follow popular categories. The new research, published in Strategic Management Journal, uses Korean pop music — or K-pop — to demonstrate how the status of entertainment agencies affects how idol groups shift categories, an effect that is also limited by the artists’ gender. The research — from Heeyon Kim of Cornell University, Yoonjeoung Heo of Xi'an Jiaotong-Liverpool University, and Chi-Nien Chung of Hong ...

Dr. Juchan Yang’s research team at the Hydrogen & Battery Materials Center, from the Energy & Environment Materials Research Division of the Korea Institute of Materials Science (KIMS), has developed a composite catalyst using the novel material MXene that suppresses the generation of chloride ions-one of the key challenges in seawater electrolysis. This research outcome is expected to accelerate the practical application of seawater electrolysis technology by enabling stable hydrogen production even in seawater. Hydrogen is gaining attention as an eco-friendly energy source that emits no carbon. However, conventional water electrolysis ...

Gene therapy offers the possibility of addressing cancer at its molecular roots by targeting disease-causing genes rather than relying solely on surgery, chemotherapy, or radiotherapy. Among RNA-based strategies, microRNA (miRNA) sponges and short-hairpin RNAs (shRNAs) have emerged as promising tools to silence oncogenes and restore tumor-suppressor pathways. However, clinical application remains constrained by delivery inefficiency, instability, and off-target toxicity. Viral and non-viral vectors each present strengths and limitations: while viral vectors provide high transfection efficiency, they often cause immune responses and mutagenesis risks; non-viral ...

In November 2016, India’s government abruptly invalidated its two highest-value banknotes, wiping out about 86 percent of the nation’s cash supply overnight. Known as the Great Indian Demonetization, the move was intended to curb corruption and encourage the adoption of digital payments. The sudden shift sparked chaos. Long lines formed outside banks as people scrambled to exchange their money before it became worthless. Small business owners and street vendors, many of whom relied almost ...

An estimated 7.2 million Americans over age 65 currently live with Alzheimer’s disease (AD). That number is expected to nearly double to 13.8 million by 2060. These increases reflect more than demographic shifts; they point to a growing public health crisis that requires a new, proactive approach. While chronological age is the strongest known risk factor for cognitive decline, losing cognitive function is not an inevitable part of aging. As AD and other forms of cognitive decline continue to rise at an alarming rate, researchers from Florida Atlantic University’s Charles E. Schmidt College of Medicine, highlight a powerful ...

NEW YORK – September 16, 2025 – The Blavatnik Family Foundation and The New York Academy of Sciences are proud to announce the three Laureates and six Finalists of the 2025 Blavatnik Regional Awards for Young Scientists, the Blavatnik Awards’ flagship prize that honors outstanding postdoctoral scientists from academic research institutions across New York, New Jersey, and Connecticut.    Honoring early-career excellence in the categories of Life Sciences, Physical Sciences & Engineering, ...

Scientists created the most accurate three-dimensional map of star-formation regions in our Milky Way galaxy, based on data from the European Space Agency’s Gaia space telescope. This map will teach us more about these obscure cloudy areas, and the hot young stars that shape them.   It is notoriously difficult to map and study regions in space where stars form because they are usually hidden from view by thick clouds of gas and dust, whose distances cannot be directly measured. Gaia can’t see these clouds directly, but it can measure stellar positions and the ...