About The Study: In this cross-sectional study of children ages 9 to 10, moderately preterm birth was associated with long-term cognitive problems independent of socioeconomic status, genetics, and other risk factors. These findings underscore the need for continued follow-up of all preterm children, with particular focus on those born before 34 weeks’ gestational age, because they may face greater developmental challenges over time. Corresponding Author: To contact the corresponding author, Samson Nivins, PhD, email samson.nivins@ki.se. To ...

New York, NY [April 14, 2025]—A new multicenter study by researchers at the Icahn School of Medicine at Mount Sinai, in collaboration with the National Cancer Institute-funded Clinical Proteomic Tumor Analysis Consortium (CPTAC) and colleagues around the world, has discovered that the genes we are born with—known as germline genetic variants—play a powerful, underappreciated role in how cancer develops and behaves. Published in the April 14 online issue of Cell [https://doi.org/10.1016/j.cell.2025.03.026], the study is the first to detail how millions of inherited genetic differences influence the activity of thousands of proteins within tumors. Drawing on data ...

The number of California teens who have been treated for self-harm has ballooned in recent years, with an especially concerning increase among multiracial girls, according to new research from the University of California, Berkeley, published today (Monday, April 14) in JAMA Pediatrics. Using data from California emergency departments and inpatient care facilities from 2005 to 2021 — 231,232 reports in total — researchers examined both how the rate of annual nonfatal self-harm incidents has changed, as well as rate differences based on age, sex, and race and ethnicity. The study ...

Most cancer genome studies have focused on mutations in the tumor itself and how such gene variants allow a tumor to grow unchecked. A new study, led by researchers at Washington University School of Medicine in St. Louis, takes a deep dive into inherited cancer mutations measured in a healthy blood sample and reports how those mutations might take a toll on the body’s cells starting at birth, perhaps predisposing a person to develop cancers at various stages of life. The authors analyzed the inherited genomes of more than 1,000 cancer patients and determined how inherited mutations — ...

Popular CT Scans Could Account for 5% of All Cancer Cases A Year  Radiation from imaging could lead to lung, breast and other future cancers, with 10-fold increased risk for babies   CT scans may account for 5% of all cancers annually, according to a new study out of UC San Francisco that cautions against overusing and overdosing CTs.   The danger is greatest for infants, followed by children and adolescents. But adults also are at risk, since they are the most likely to get scans.   Nearly 103,000 cancers are predicted to result from the 93 million CTs that were ...

Deep-sea mining (DSM) not only poses significant environmental, social, and economic risks that may have far-reaching implications for coastal communities and Small Island Developing States (SIDS), it is also likely to negatively affect the business community, including insurers and investors, says a new study by researchers from the University of British Columbia and the Dona Bertarelli Philanthropy. DSM operations are expected to increase the negative impact on environmental indicators by up to 13 per cent, a change categorized as having “great” significance, relative to the “without” DSM scenario, ...

Background Robo-pigeon / Cyborg pigeon is a new type of hybrid intelligent robotic system developed by combining micro-implantable brain-computer interface (BCI) and micro-electro-mechanical system (MEMS) technologies. By integrating the perception, motion and autonomous intelligence of real pigeons with the high precision, repeatability and controllability of MEMS, a flexible and efficient "biological flight platform" is formed, which has a broad application prospect in key fields such as disaster rescue, national defense security and environmental monitoring. However, ...

Whether it’s for your vehicle or your home, from small-scale uses to the largest, the debate over the most efficient and cost-effective fuels continues. Currently, there’s no shortage of options either. Nuclear power provides an alternative to more conventional energy options but requires rigorous systems monitoring and safety procedures. Machine learning could make keeping a close eye on key elements of nuclear systems easier and response time to issues faster. Syed Bahauddin Alam, an assistant professor ...

Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths worldwide, with over 70% of patients diagnosed at an advanced stage due to the absence of symptoms. A key characteristic of advanced HCC is extrahepatic metastasis, particularly pulmonary metastasis, which is associated with a poor prognosis. Although multitargeted tyrosine kinase inhibitors (TKIs) and immune checkpoint inhibitors have limited efficacy when used alone in advanced HCC, their combination can enhance outcomes for patients with pulmonary metastases. Meanwhile, pulmonary metastasectomy ...

A review published recently in Wearable Electronics examines the current applications and persistent challenges of flexible wearable technologies in aerospace medicine. As human space exploration progresses toward extended-duration missions, the imperative for real-time monitoring of astronauts' physiological and psychological well-being has become increasingly critical. The unique space environment characterized by microgravity conditions, cumulative radiation exposure, and extreme thermal fluctuations presents multifaceted health risks to crew members. Flexible wearable systems, equipped ...

Complications during pregnancy (or adverse pregnancy outcomes), like gestational diabetes and newly developed high blood pressure, act as nature’s stress test and may uncover an individual’s risk for heart disease later in life, according to new research published in the JACC, the flagship journal of the American College of Cardiology. The study also highlights how weight management before pregnancy may not only improve maternal health but also reduce future cardiovascular disease risk. The observational study, which ...

Cardiovascular disease is by far the most common cause of death worldwide, and myocardial infarction is the most common acute event. For those who survive a myocardial infarction, the risk of a new heart attack is greatest in the first year after the initial event because the blood vessels are more sensitive, making it easier for blood clots to develop. Reducing the “bad” cholesterol in the blood stabilises changes in the vessels, decreasing the risk for new events. The current established routine treatment is to treat with high-potency statins, immediately after the infarction. However, the majority ...

LUND UNIVERSITY/IMPERIAL COLLEGE LONDON PRESS RELEASE   [Peer-reviewed /Simulation/Modelling / People]   UNDER EMBARGO UNTIL: Monday 14th April 2025 10:00 am US Eastern Time / 3:00 pm UK Time Combination of drugs could prevent thousands of heart attacks Patients who receive an add-on medication soon after a heart attack have a significantly better prognosis than those who receive it later, or not all. This is according to a new study from researchers at Lund University in Sweden and Imperial College London. ...

New tool for cutting DNA: promising prospects for biotechnology  An INRS team discovers a new family of enzymes capable of inducing targeted cuts in single-stranded DNA   A few years ago, the advent of technology known as CRISPR was a major breakthrough in the scientific world. Developed from a derivative of the immune system of bacteria, CRISPR enables double strands of nucleotides in deoxyribonucleic acid (DNA) to be cut.  This makes it possible to specifically modify a targeted gene in plant, animal and human cells. Ultimately, CRISPR became a preferred method in the search for treatments for acquired or hereditary diseases.   Recently, ...

Victoria, BC— For the first time, footprints of armoured dinosaurs with tail clubs have been identified, following discoveries made in the Canadian Rockies. The 100-million-year-old fossilized footprints were found at sites at both Tumbler Ridge, BC, and northwestern Alberta. There are two main groups of ankylosaurs. Nodosaurid ankylosaurs have a flexible tail and four toes, while ankylosaurid ankylosaurs have a sledgehammer-like tail club, and only three toes on their feet. Unlike the well-known ankylosaur footprints called Tetrapodosaurus ...

A research paper by scientists at Beijing Institute of Technology and City University of Hong Kong presented a versatile electrodynamics simulation model designed to analyze the driving forces of partially filled electrodes to optimize the structural parameters of Digital microfluidic chips. The research paper, published on Mar. 06, 2025 in the journal Cyborg and Bionic Systems, utilizes finite element analysis to determine the voltage distribution within the Digital microfluidic chip and calculates the driving force acting on the droplets using the principles of virtual work. Digital microfluidic chips (DMCs) have shown huge potential for biochemical analysis ...

COLUMBUS, Ohio – Insomnia and hazardous drinking are so closely intertwined that estimates suggest at least one-third, and as many as 91%, of people who have a hard time with sleep also misuse alcohol. A new study suggests that perceived stress and depression factor into the relationship between the two conditions – perhaps not a surprise. But because the relationship between insomnia and heavy drinking goes in both directions, the influence of stress or depression depends on which condition came first, the analysis found. “We were most interested in how insomnia leads to drinking, and we found that seems to occur primarily through ...

Years of research in the field of genetics have offered interesting insights spanning the origins and development of heredity and traits, offering valuable information on its influence on every aspect of life, right from eye color to susceptibility to certain diseases. But how do our genes influence the way we act, react to threats, and interact with others? Despite the recent advances in genetics, understanding the genetic foundations of behavior remains one of biology’s most fascinating challenges. Scientists have long turned to simpler organisms to help answer these questions, with the humble fruit fly emerging as an ideal candidate. These tiny insects share ...

DARIEN, IL — The American Academy of Sleep Medicine has released a new position statement emphasizing the clinical significance of sleepiness and its impact on performance, health, mood, safety, and quality of life. The position states that sleepiness is a critical patient-reported outcome that is associated with an increased risk for adverse health effects and diminished quality of life. The statement urges health care professionals, policymakers, and researchers to prioritize the evaluation, management, and treatment of sleepiness ...

A new USC study suggests that gut imbalances in children with autism may create an imbalance of metabolites in the digestive system — ultimately disrupting neurotransmitter production and influencing behavioral symptoms. The research, published today in Nature Communications, adds to a growing body of science implicating the “gut-brain” axis in autism. The discovery raises the possibility of new treatment avenues. It’s an example of how research at USC, and other universities, drives ...

A new study has shed unprecedented light on the highly variable and climate-sensitive routes that substances from Siberian rivers use to travel across the Arctic Ocean. The findings raise fresh concerns about the increasing spread of pollutants and the potential consequences for fragile polar ecosystems as climate change accelerates. The international research, published today in Nature Communications and led by the University of Bristol, in the UK, provides the clearest ever picture of how the underlying transport system, known as the Transpolar Draft, operates. It also uncovers the various factors controlling this major Arctic surface current, ...

An international team of researchers may have answered one of space science’s long-running questions – and it could change our understanding of how life began.   Carbon-rich asteroids are abundant in space yet make up less than 5 per cent of meteorites found on Earth.   An international team of scientists from Curtin University’s School of Earth and Planetary Sciences, the International Centre for Radio Astronomy (ICRAR), the Paris Observatory and more scoured the globe to find an answer.   Published today in Nature Astronomy, researchers analysed close to 8500 meteoroids and meteorite impacts, using data from ...

Statement Highlights: While the strongest evidence exists that getting sufficient sleep (duration of sleep) is important for overall health , other components of sleep health, such as consistent bedtime, uninterrupted sleep, daytime functioning and self-reported sleep satisfaction, also contribute to cardiometabolic health and related risk factors, including heart disease, stroke, high blood pressure, high cholesterol, inflammation, glucose intolerance, obesity and obstructive sleep apnea. Differences in sleep health may contribute to increased risk factors and worse health outcomes, particularly for people in under-resourced communities and individuals ...

Researchers from the University of Birmingham have uncovered answers that provide the detail to explain two specific DNA repair processes that have long been in question. The publication of two papers demonstrates how work led by laboratories from the Department of Cancer and Genomic Sciences, and School of Biosciences at the University of Birmingham has made strides in understanding how the repair process is correctly orchestrated. The importance of understanding DNA repair Our cells protect their DNA by constantly monitoring and repairing any damage. When DNA is damaged, internal signals activate within the cell to pinpoint the damage and recruit specialised proteins—DNA ...

Microplastics and the much smaller nanoplastics enter the human body in various ways, for example through food or the air we breathe. A large proportion is excreted, but a certain amount remains in organs, blood and other body fluids. In the FFG bridge project Nano-VISION, which was launched two years ago together with the start-up BRAVE Analytics, a team led by Harald Fitzek from the Institute of Electron Microscopy and Nanoanalysis at Graz University of Technology (TU Graz) and an ophthalmologist from Graz addressed the question of whether nanoplastics also play a role in ophthalmology. The project partners have now been able to develop a method for detecting and quantifying nanoplastics ...