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Non-genetic theories of cancer address inconsistencies in current paradigm

Non-genetic theories of cancer address inconsistencies in current paradigm
2025-03-18
It’s time for researchers to reconsider the current paradigm of cancer as a genetic disease, argued Sui Huang from the Institute for Systems Biology, USA, and colleagues in a new essay published March 18th in the open-access journal PLOS Biology. The prevailing theory on the origin of cancer is that an otherwise normal cell accumulates genetic mutations that allow it to grow and reproduce unchecked. This paradigm has driven large-scale cancer genome sequencing projects, such as The Cancer Genome Atlas, to identify cancer-driving mutations ...

Food and non-alcoholic drink products in Mexico were substantially reformulated to be healthier following the 2020 introduction of warning labels identifying products with excessive content of calorie

Food and non-alcoholic drink products in Mexico were substantially reformulated to be healthier following the 2020 introduction of warning labels identifying products with excessive content of calorie
2025-03-18
Food and non-alcoholic drink products in Mexico were substantially reformulated to be healthier following the 2020 introduction of warning labels identifying products with excessive content of calories, fat, salt, sugar, sweetener and caffeine     In your coverage, please use this URL to provide access to the freely available paper in PLOS Medicine: http://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1004533 Article title: Product reformulation in non-alcoholic beverages and foods after the implementation ...

Conservation efforts are bringing species back from the brink, even as overall biodiversity falls

Conservation efforts are bringing species back from the brink, even as overall biodiversity falls
2025-03-18
A major review of over 67,000 animal species has found that while the natural world continues to face a biodiversity crisis, targeted conservation efforts are helping bring many species back from the brink of extinction. The study draws on data from the IUCN Red List, the world’s largest database of species conservation status. The researchers say their results, reported in the journal PLOS Biology, highlight both the successes and the need for urgent action. The world is facing a global biodiversity crisis, with 28% of more than 160,000 assessed species threatened with extinction, and an estimated one million species facing this fate due to human activities. ...

Conservation efforts analysis reveals which actions are most helpful for endangered species status

Conservation efforts analysis reveals which actions are most helpful for endangered species status
2025-03-18
Targeted conservation actions are essential to prevent wildlife extinctions, but more efforts are needed to fully recover biodiversity, according to a study published March 18th in the open-access journal PLOS Biology by Ashley Simkins of the University of Cambridge, UK and colleagues. Out of over 166,000 species assessed by the International Union for Conservation of Nature, around 28% are threatened with extinction. Global efforts to prevent extinction and recover biodiversity have had some success, but there is limited data to show which conservation actions are most effective. In this study, Simkins and colleagues compile information ...

JSCAI special issue explores the transformative role of artificial intelligence in interventional cardiology

2025-03-18
WASHINGTON —The Journal of the Society for Cardiovascular Angiography & Interventions (JSCAI) proudly announces the publication of a groundbreaking special issue: The Role of Artificial Intelligence in Cardiovascular Interventions.   This issue explores how artificial intelligence (AI) is revolutionizing interventional cardiology, from diagnostic precision to procedural planning and patient outcomes. It features a collection of original research, reviews, and viewpoints that delve into AI’s applications across ...

Wayne State University research making strides in autonomous vehicle and machine systems to make them safer, more effective

Wayne State University research making strides in autonomous vehicle and machine systems to make them safer, more effective
2025-03-18
DETROIT — A grant to Wayne State University from the National Science Foundation (NSF) is opening new doors for researchers and students to explore the future of autonomous vehicles, machines and drones. Zheng Dong, Ph.D., assistant professor of computer science in Wayne State’s School of Engineering, was awarded a five-year, $595,611 NSF grant for the project, "CAREER: ChronosDrive: Ensuring Timing Correctness in DNN-Driven Autonomous Vehicles with Accelerator-Enhanced Real-Time SoC Integration." “We ...

Thorny skates come in snack and party sizes. After a century of guessing, scientists now know why.

Thorny skates come in snack and party sizes. After a century of guessing, scientists now know why.
2025-03-18
When Jeff Kneebone was a college student in 2002, his research involved a marine mystery that has stumped curious scientists for the last two decades. That mystery had to do with thorny skates in the North Atlantic. In some parts of their range, individuals of this species come in two distinct sizes, irrespective of sex, and no one could figure out why. At the time, neither could Kneebone. In a new study, Kneebone and researchers from the Florida Museum of Natural History say they’ve finally found an answer. And it’s all thanks to COVID-19. People have known about the size discrepancy in thorny skates for nearly a century, but it became critically ...

When did human language emerge?

2025-03-18
It is a deep question, from deep in our history: When did human language as we know it emerge? A new survey of genomic evidence suggests our unique language capacity was present at least 135,000 years ago. Subsequently, language might have entered social use 100,000 years ago. Our species, Homo sapiens, is about 230,000 years old. Estimates of when language originated vary widely, based on different forms of evidence, from fossils to cultural artifacts. The authors of the new analysis took a different approach. ...

Meteorites: A geologic map of the asteroid belt

Meteorites: A geologic map of the asteroid belt
2025-03-18
March 18, 2025, Mountain View, CA -- Where do meteorites of different type come from? In a review paper in the journal Meteoritics & Planetary Science, published online this week, astronomers trace the impact orbit of observed meteorite falls to several previously unidentified source regions in the asteroid belt.  “This has been a decade-long detective story, with each recorded meteorite fall providing a new clue,” said meteor astronomer and lead author Peter Jenniskens of the SETI Institute and NASA Ames Research Center. “We now have the first outlines of a geologic map of the asteroid belt.”  Ten years ago, ...

Study confirms safety and efficacy of higher-dose-per-day radiation for early-stage prostate cancer

2025-03-18
A new large-scale study co-led by UCLA Health Jonsson Comprehensive Cancer Center investigators provides the strongest evidence yet that a shorter, standard-dose course radiation treatment is just as effective as conventional radiotherapy for prostate cancer, without compromising the safety of patients. The shorter approach, known as isodose moderately hypofractionated radiotherapy (MHFRT), delivers slightly higher doses of radiation per session, allowing the total treatment duration to be over four to five weeks instead of seven to eight weeks. According to the study, patients who received this type ...

Virginia Tech researchers publish revolutionary blueprint to fuse wireless technologies and AI

Virginia Tech researchers publish revolutionary blueprint to fuse wireless technologies and AI
2025-03-18
There’s a major difference between humans and current artificial intelligence (AI) capabilities: common sense. According to a new visionary paper by Walid Saad, professor in the College of Engineering and the Next-G Wireless Lead at the Virginia Tech Innovation Campus, a true revolution in wireless technologies is only possible through endowing the system with the next generation of AI that can think, imagine, and plan akin to humans. Published in the Proceedings of the IEEE Journal's Special Issue on the Road to 6G with Ph.D. student Omar Hashash and postdoctoral associate Christo Thomas, the paper's findings suggest: The missing link in the wireless revolution is ...

Illinois study: Extreme heat impacts dairy production, small farms most vulnerable

Illinois study: Extreme heat impacts dairy production, small farms most vulnerable
2025-03-18
URBANA, Ill. – Livestock agriculture is bearing the cost of extreme weather events. A new study from the University of Illinois Urbana-Champaign explores how heat stress affects U.S. dairy production, finding that high heat and humidity lead to a 1% decline in annual milk yield. Small farms are hit harder than large farms, which may be able to mitigate some of the effects through management strategies. “Cows are mammals like us, and they experience heat stress just like we do. When cows are exposed to extreme heat, it can have a range of negative physical effects. There is an increased risk of infection, restlessness, and decreased ...

Continuous glucose monitors can optimize diabetic ketoacidosis management

2025-03-18
Diabetic ketoacidosis is a common severe complication of diabetes, which develops when the body can’t produce enough insulin. During DKA the body starts breaking down fat, causing a buildup of acids in the bloodstream. The symptoms often include thirst, weakness, nausea and confusion. Concerningly, this condition accounts for more than 500,000 hospital days per year, often in the intensive care unit, with an estimated cost of $2.4 billion. In a study, published in CHEST Critical Care, University of Michigan researchers show that using continuous glucose monitors can help measure glucose accurately during DKA and ...

Time is not the driving influence of forest carbon storage, U-M study finds

2025-03-18
Figures and photos   It is commonly assumed that as forest ecosystems age, they accumulate and store, or "sequester," more carbon.   A new study based at the University of Michigan Biological Station untangled carbon cycling over two centuries and found that it's more nuanced than that.   The synergistic effects of forest structure, the composition of the tree and fungal communities, and soil biogeochemical processes have more influence on how much carbon is being sequestered above and below ground than previously thought.   The ...

Adopting zero-emission trucks and buses could save lives, prevent asthma in Illinois

2025-03-18
Guided by the lived experiences of community partners, Northwestern University scientists have simulated the effects of zero-emission vehicle (ZEV) adoption on future air quality for the greater Chicago area. The results were published today (March 18) in the journal Frontiers of Earth Science. Motivated by California’s Advanced Clean Trucks (ACT) policy, Neighbors for an Equitable Transition to Zero-Emissions (NET-Z) Illinois members partnered with Northwestern researchers to explore how a similar strategy might play out in Cook County and the surrounding areas. To develop a model that more realistically simulates ...

New fossil discovery reveals how volcanic deposits can preserve the microscopic details of animal tissues

New fossil discovery reveals how volcanic deposits can preserve the microscopic details of animal tissues
2025-03-18
An analysis of a 30,000-year-old fossil vulture from Central Italy has revealed for the first time that volcanic rock can preserve microscopic details in feathers - the first ever record of such a preservation. An international team, led by Dr Valentina Rossi (University College Cork, Ireland), discovered a new mode of preservation of soft tissues that can occur when animals are buried in ash-rich volcanic sediments. The new research, published in the scientific journal Geology, reveals that the feathers ...

New chromosome barcode system unveils genetic secrets of alfalfa

New chromosome barcode system unveils genetic secrets of alfalfa
2025-03-18
In a recent study, scientists have developed a revolutionary chromosome identification system for alfalfa, one of the world's most economically vital forage crops. Leveraging an advanced Oligo-fluorescence in situ hybridization (FISH) barcode technique, researchers successfully mapped and identified all chromosomes in alfalfa, uncovering unexpected chromosomal anomalies, including aneuploidy and large segment deletions. This breakthrough not only enhances molecular cytogenetics but also sheds light on the genetic stability ...

Reusing old oil and gas wells may offer green energy storage solution

2025-03-18
UNIVERSITY PARK, Pa. — Moving from fossil fuels to renewable energy sources like wind and solar will require better ways to store energy for use when the sun is not shining or the wind is not blowing. A new study by researchers at Penn State found that taking advantage of natural geothermal heat in depleted oil and gas wells can improve the efficiency of one proposed energy storage solution: compressed-air energy storage (CAES). The researchers recently published their findings in the Journal of Energy Storage. CAES plants compress air and store it underground when energy demand is low and then extract the air to create electricity when demand ...

Natural insect predators may serve as allies in spotted lanternfly battle

Natural insect predators may serve as allies in spotted lanternfly battle
2025-03-18
UNIVERSITY PARK, Pa. — Insect predators found in the United States could help keep spotted lanternfly populations in check while potentially reducing reliance on chemical control methods, according to a new study conducted by researchers at Penn State. Led by entomologists in Penn State’s College of Agricultural Sciences and published in Arthropod-Plant Interactions, the study evaluated the effectiveness of various insects in potentially controlling spotted lanternfly populations. The invasive pest, first detected in the United States in 2014, has spread across at least 18 states, causing significant damage to vineyards, orchards ...

Rice research team creates universal RNA barcoding system for tracking gene transfer in bacteria

Rice research team creates universal RNA barcoding system for tracking gene transfer in bacteria
2025-03-18
In the microscopic world of bacteria, gene transfer is a powerful mechanism that can alter cellular function, drive antibiotic resistance and even shape entire ecosystems. Now an interdisciplinary group of researchers at Rice University has developed an innovative RNA “barcoding” method to track these genetic exchanges in microbial communities, providing new insights into how genes move across species. The findings were recently published in Nature Biotechnology. “We’ve long known that bacteria swap genes in ways that impact human health, biotechnology and environmental stability,” said James Chappell, associate professor of biosciences ...

New genetic pathway unlocks drought-resistant cucumbers with fewer branches

New genetic pathway unlocks drought-resistant cucumbers with fewer branches
2025-03-18
A new discovery has unveiled a genetic module, CsTIE1-CsAGL16, that simultaneously regulates lateral branch development and drought tolerance in cucumbers. This dual-function genetic pathway offers a promising new approach to breeding cucumber varieties that are both resilient to water scarcity and tailored to market preferences. By deciphering how these genes coordinate water conservation and branch growth, researchers have opened new doors for improving crop adaptability and productivity in the face of climate change. Drought stress poses a major challenge to ...

New high-definition pictures of the baby universe

New high-definition pictures of the baby universe
2025-03-18
New research by the Atacama Cosmology Telescope (ACT) collaboration has produced the clearest images yet of the universe’s infancy – the earliest cosmic time yet accessible to humans. Measuring light that traveled for more than 13 billion years to reach a telescope high in the Chilean Andes, the new images reveal the universe when it was about 380,000 years old – the equivalent of hours-old baby pictures of a now middle-aged cosmos.  “We are seeing the first steps towards making the earliest stars and galaxies,” says Suzanne Staggs, director of ACT and Henry ...

Zhou conducting GPU modeling research

2025-03-18
Keren Zhou, Assistant Professor, Computer Science, College of Engineering and Computing (CEC), received funding for: “GPU Modeling Research of Smart Modeling and Simulation for HPC (SMASH).” Zhou and his collaborators will complete research and development tasks.  Zhou received $65,648 from Brookhaven National Laboratory on a subaward from the U.S. Department of Energy for this research. Funding began in Feb. 2025 and will end in late Sept. 2025.                     ...

Twenty-two year study: Adolescents engaged in fewer external risky behaviors but some report increasing mental health concerns

2025-03-18
Between 1999-2021, U.S. adolescents steadily desisted from risky behaviors such as substance use and violence, and from reporting a combination of both risky behaviors and mental health symptoms. Yet a comparatively small but growing proportion of youth demonstrated elevated symptoms of depression, according to a report to be published in the April 2025 issue of Pediatrics. The study, published online on March 18, and titled “Trends in Mental and Behavioral Health Risks in Adolescents: 1999-2021,” analyzed data from the national biennial Youth Risk Behavior Surveys distributed by the Centers for Disease Control and Prevention. A ...

Leafcutter ants recognize and fight pathogen even 30 days after initial contamination, study shows

Leafcutter ants recognize and fight pathogen even 30 days after initial contamination, study shows
2025-03-18
A study conducted by researchers from São Paulo State University (UNESP), in Brazil, and collaborators shows that lemon leafcutter ants (Atta sexdens) exhibit behaviors that go beyond so-called social immunity, i.e. the ability to detect pathogens and try to get rid of them for the benefit of the colony. In an article published in the journal Proceedings of the Royal Society B, scientists report that these insects are able to recognize a pathogenic fungus they have already been exposed ...
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