Introducing our new cohort of AGA Future Leaders
2025-03-14
We’re thrilled to announce the 16 distinguished early-career gastroenterologists and hepatologists selected for our 2025-2026 class of AGA Future Leaders. This AGA program cultivates effective leadership skills for professional advancement in AGA and within the field of digestive diseases.
Meet the AGA Future Leaders Class of 2025-2026
Lubin Arevalo, MD
Veroushka Ballester, MD, MS
Victor Chedid, MD, MS
Ryan Fawley, MD
Melissa Hershman, MD
Pichamol Jirapinyo, MD, MPH
Babu Pappu Mohan, MD
Carolyn Newberry, MD
Long ...
Sharks are dying at alarming rates, mostly due to fishing. Retention bans may help
2025-03-14
Despite the fear they may inspire in humans, sharks have far more reason to fear us. Nearly one-third of sharks are threatened with extinction globally, mostly as a result of fishing.
A team led by researchers at UC Santa Barbara discovered that mandates to release captured sharks won’t be enough to prevent the continued decline of these important ocean predators. These findings, published in Fish & Fisheries, highlight the importance of monitoring shark populations and combining different strategies for managing their numbers.
Some ...
Engineering excellence: Engineers with ONR ties elected to renowned scientific academy
2025-03-14
Three esteemed engineers with ties to the Office of Naval Research (ONR) have been elected to the prestigious National Academy of Engineering (NAE) Class of 2025. NAE members are among the world’s most accomplished engineers from business, academia and government.
“On behalf of the Office of Naval Research, I’m proud to extend my sincerest congratulations to these new members of the National Academy of Engineering,” said Chief of Naval Research Rear Adm. Kurt Rothenhaus. “Not only have these accomplished engineering professionals supported and conducted valuable naval-relevant research, they’re also enhancing the strength and prosperity of our nation by serving ...
New CRISPR-based diagnostic test detects pathogens in blood without amplification
2025-03-14
Bioengineering professor and The Grainger College of Engineering’s Dean, Rashid Bashir, led a team of researchers in a project that’s resulted in new technology that offers rapid, highly sensitive detection of multi-drug-resistant bacteria and other pathogens at low concentrations.
This research was featured in an article in the Proceedings of the National Academy of Sciences of the United States of America (PNAS).
Researchers designed a CRISPR-based test that rapidly detects low levels of pathogen genetic material in blood. This is done without the need for nucleic acid amplification.
In ...
Immunotherapy may boost KRAS-targeted therapy in pancreatic cancer
2025-03-14
PHILADELPHIA – Adding immunotherapy to a new type of inhibitor that targets multiple forms of the cancer-causing gene mutation KRAS kept pancreatic cancer at bay in preclinical models for significantly longer than the same targeted therapy by itself, according to researchers from the Perelman School of Medicine at the University of Pennsylvania and Penn Medicine’s Abramson Cancer Center. The results, published in Cancer Discovery, prime the combination strategy for future clinical trials.
Combatting the “undruggable” ...
Growing solar: Optimizing agrivoltaic systems for crops and clean energy
2025-03-14
Agrivoltaic systems, which combine solar power generation with agricultural practices, offer a promising solution to the growing demand for both renewable energy and food production. By integrating solar panels with crops, these systems not only address the land use conflict between agriculture and energy production, but they also provide important benefits such as reducing crop water stress and offering protection against extreme weather events. In addition, agrivoltaics can contribute to biodiversity by providing pollinator habitats and forage production. ...
Scientists discover how to reactivate cancer’s molecular “kill switch”
2025-03-14
Alternative RNA splicing is like a movie editor cutting and rearranging scenes from the same footage to create different versions of a film. By selecting which scenes to keep and which to leave out, the editor can produce a drama, a comedy, or even a thriller—all from the same raw material. Similarly, cells splice RNA in different ways to produce a variety of proteins from a single gene, fine-tuning their function based on need. However, when cancer rewrites the script, this process goes awry, fueling tumor growth and survival.
In a recent study reported in the Feb. 15 issue of Nature ...
YouTube influencers: gaming’s best friend or worst enemy?
2025-03-14
New INFORMS Marketing Science Study Key Takeaways:
YouTube influencers increase player engagement and playtime but often reduce game purchases, especially for story-driven games.
A unique event in YouTube’s history, the “Adpocalypse,” allowed researchers to measure the causal impact of influencer content, revealing its complex effects on game sales and usage.
Game developers must align their business models with influencer marketing, because games with in-game purchases benefit from exposure, while ...
uOttawa scientists use light to unlock secret of atoms
2025-03-14
A team of researchers from the University of Ottawa has made significant strides in understanding the ionization of atoms and molecules, a fundamental process in physics that has implications for various fields including x-ray generation and plasma physics.
Think about atoms - the building blocks of everything around us. Sometimes, they lose their electrons and become charged particles (that's ionization). It happens in lightning, in plasma TVs, and even in the northern lights. Until now, scientists thought they could only control this process in limited ways.
Led by Ravi Bhardwaj, Full Professor at uOttawa’s Department of Physics, and PhD student Jean-Luc Begin, in collaboration ...
NJIT mathematician to help map Earth's last frontier with Navy grant
2025-03-14
We’ve mapped nearly all of Mars’ surface from orbit, yet we know less about Earth’s ocean floor — almost 75% remains unmapped in high resolution.
This terrestrial blind spot is driving NJIT Mathematics Professor Eliza Michalopoulou’s latest research, funded by the Office of Naval Research (ONR). The project aims to improve how scientists explore the vast, uncharted ocean floor through sound.
“Mapping the seabed is a challenging endeavor due to the extreme conditions,” said Michalopoulou, ...
NASA atmospheric wave-studying mission releases data from first 3,000 orbits
2025-03-14
Following the 3,000th orbit of NASA’s AWE (Atmospheric Waves Experiment) aboard the International Space Station, researchers publicly released the mission’s first trove of scientific data, crucial to investigate how and why subtle changes in Earth’s atmosphere cause disturbances, as well as how these atmospheric disturbances impact technological systems on the ground and in space.
“We’ve released the first 3,000 orbits of data collected by the AWE instrument in space and transmitted back to Earth,” said Ludger Scherliess, principal investigator for the mission and physics professor at Utah State University. “This is a view of atmospheric ...
‘Microlightning’ in water droplets may have sparked life on Earth
2025-03-14
Life may not have begun with a dramatic lightning strike into the ocean but from many smaller “microlightning” exchanges among water droplets from crashing waterfalls or breaking waves.
New research from Stanford University shows that water sprayed into a mixture of gases thought to be present in Earth’s early atmosphere can lead to the formation of organic molecules with carbon-nitrogen bonds, including uracil, one of the components of DNA and RNA.
The study, published in the journal Science Advances, adds evidence – and a new angle – to the much-disputed Miller-Urey ...
Smoke from wildland-urban interface fires more deadly than remote wildfires
2025-03-14
EMBARGOED until Friday, March 14 at 2:00 p.m. Eastern Time (12 noon MT)
Contacts:
David Hosansky, NSF NCAR and UCAR Manager of Media Relations
hosansky@ucar.edu
303-497-8611
Audrey Merket, NSF NCAR and UCAR Science Writer and Public Information Officer
amerket@ucar.edu
303-497-8293
The smoke from fires that blaze through the wildland-urban interface (WUI) has far greater health impacts than smoke from wildfires in remote areas, new research finds.
The study, published this week in Science Advances, estimates that emissions from WUI fires are proportionately about three times more likely to lead ...
What’s your body really worth? New AI model reveals your true biological age from 5 drops of blood
2025-03-14
Osaka-Japan - We all know someone who seems to defy aging—people who look younger than their peers despite being the same age. What’s their secret? Scientists at Osaka University (Japan) may have found a way to quantify this difference. By incorporating hormone (steroid) metabolism pathways into an AI-driven model, they have developed a new system to estimate a person’s biological age a measure of how well their body has aged, rather than just counting the years since birth.
Using just five drops of ...
Protein accidentally lassos itself, helping explain unusual refolding behavior
2025-03-14
UNIVERSITY PARK, Pa. — Proteins are long molecules that must fold into complex three-dimensional structures to perform their cellular functions. This folding process occasionally goes awry, resulting in misfolded proteins that, if not corrected, can potentially lead to disease. Now, a new study has described a potential mechanism that could help explain why some proteins refold in a different pattern than expected. The researchers, led by chemists at Penn State, found that a type of misfolding, in which the ...
With bird flu in raw milk, many in U.S. still do not know risks of consuming it
2025-03-14
PHILADELPHIA – Although the Food and Drug Administration (FDA) located H5N1 bird flu virus in samples of raw, or unpasteurized, milk in tests in four states in April 2024, and bird flu has been detected in commercially sold raw milk, many Americans do not know that consuming raw milk and its products poses greater health risks than consuming pasteurized milk and its products, especially for children. Consuming raw milk can expose one to Salmonella, E. coli, Campylobacter, Cryptosporidium, Listeria, and Brucella – and, potentially, H5N1 bird flu.
A majority of U.S. adults (56%) knows that drinking raw milk from cows, sheep, or goats is less safe than drinking pasteurized milk. ...
University of Minnesota research team awarded $3.8 million grant to develop cell therapy to combat Alzheimer’s disease
2025-03-14
MINNEAPOLIS/ST. PAUL (03/14/2025) — A University of Minnesota research team was recently awarded a five-year, $3.8 million grant from the U.S. National Institutes of Health to develop a new cell therapy to combat Alzheimer’s disease. More than 55 million people worldwide live with dementia, which includes Alzheimer's disease and other related conditions.
The project aims to adapt advanced techniques developed for cancer treatment to create specialized macrophages — immune cells that can surround and remove proteins from their environment — to seek out and clear harmful proteins in the brain.
"Engineered ...
UConn uncovers new clue on what is leading to neurodegenerative diseases like Alzheimer’s and ALS
2025-03-14
In Nature Neuroscience, UConn School of Medicine researchers have revealed a new scientific clue that could unlock the key cellular pathway leading to devastating neurodegenerative diseases like Alzheimer’s disease, and the progressive damage to the brain’s frontal and temporal lobes in frontotemporal degeneration (FTD) and the associated disease amyotrophic lateral sclerosis (ALS).
The study, “Endothelial TDP-43 Depletion Disrupts Core Blood-Brain Barrier Pathways in Neurodegeneration,” was published on March 14, 2025. The lead author, Omar Moustafa Fathy, an MD/Ph.D. candidate at the Center for Vascular Biology at UConn School of ...
Resuscitation in out-of-hospital cardiac arrest – it’s how quickly it is done, rather than who does it
2025-03-14
Key takeaways:
The proportion of bystanders (as opposed to emergency medical services) performing cardiopulmonary resuscitation (CPR) on individuals experiencing out-of-hospital cardiac arrest (OHCA) has steadily increased over the past decades.
The study emphasises that the speed of CPR initiation, rather than who performs it, is crucial to survival and better outcomes.
Each 5-minute delay in return of spontaneous circulation in patients experiencing OCHA is associated with a 38% increased risk of death.
Based on these findings, the authors emphasise that increasing the number of individuals trained in proper CPR ...
A closer look at biomolecular ‘silly putty’
2025-03-14
Biomolecular condensates are shifting blobs in our cells that organize cellular matter. They are distinct molecular communities made of DNA, RNA and proteins that “condense” molecules to key locations, yet they frequently defy description. Partly this is because they are so small, they cannot be measured using traditional microscopes.
“These blobs were once described as being ‘liquid-like’ because some of them were observed to kiss, fuse, drip and flow like raindrops on windshields,” said Rohit Pappu, Gene K. Beare Distinguished Professor of biomedical engineering ...
Oxytocin system of breastfeeding affected in mothers with postnatal depression
2025-03-14
The oxytocin system – which helps release breast milk and strengthens the bond between mother and baby – may be affected during breastfeeding in mothers experiencing postnatal depression, finds a new study by UCL researchers.
The new research, published in Psychoneuroendocrinology, investigated the link between maternal mood and the oxytocin pathway during breastfeeding, in mothers with and without symptoms of postnatal depression.
Oxytocin is a hormone that is released in both the brain and body. It plays a central role in childbirth and breastfeeding, ...
Liquid metal-enabled synergetic cooling and charging: a leap forward for electric vehicles
2025-03-14
A recent study published in Engineering presents a novel approach to address the challenges of high-power direct current fast charging (DC-HPC) in electric vehicles (EVs). The research, led by a team from China Agricultural University, focuses on developing a synergetic cooling and charging strategy using a gallium-based liquid metal flexible charging connector (LMFCC).
As the demand for EVs grows, DC-HPC technology, especially for megawatt-level charging currents (≥1000 A), is crucial for reducing charging time. However, it brings the ...
Defensive firearm use is far less common than exposure to gun violence
2025-03-14
Those with access to firearms rarely use their weapon to defend themselves, and instead are far more likely to be exposed to gun violence in other ways, according to a Rutgers Health study.
An overwhelming majority of firearm users, or about 92%, indicated they never have used their weapons to defend themselves, with less than 1% say they did in the previous year, a new study by the New Jersey Gun Violence Research Center found.
“Adults with firearm access are far more likely to be exposed to gun violence than they are to defend themselves with their firearms,” ...
Lifetime and past-year defensive gun use
2025-03-14
About The Study: In this survey of adults with firearm access, defensive gun use (DGU) was rare relative to gun violence exposure. Perceived threats may not necessitate DGU, and given the association between DGU and gun violence exposure, the consequences of DGU may be substantial. Narratives centering DGU as a consideration in firearm policies may misstate the risk profile of firearm access.
Corresponding Author: To contact the corresponding author, Michael D. Anestis, PhD, email mda141@sph.rutgers.edu.
To access the ...
Lifetime health effects and cost-effectiveness of tirzepatide and semaglutide in US adults
2025-03-14
About The Study: This economic evaluation found that although tirzepatide and semaglutide offered substantial long-term health benefits, they were not cost-effective at current net prices. Efforts to reduce the net prices of new anti-obesity medications are essential to ensure equitable access to highly effective anti-obesity medications.
Corresponding Author: To contact the corresponding author, Jennifer H. Hwang, DO, email jennifer.hwang2@bsd.uchicago.edu.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamahealthforum.2024.5586)
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