New geological data has given more insight into the rate and magnitude of global sea level rise following the last ice age, about 11,700 years ago. This information is of great importance to understand the impact global warming has had on the ice caps and on sea level rise. The findings have been published in the scientific journal Nature by researchers from Deltares, Utrecht University, TNO Netherlands Geological Service, Delft University of Technology, the Netherlands Institute for Sea Research (NIOZ), University of Leeds, University of Sheffield, University of Amsterdam, LIAG and BGR. Better ...

Germinal centers are high-speed evolution machines. Tiny clusters in the lymph nodes, germinal centers refine antibodies through mutation and expansion until they produce high-affinity B cells adapted to keep different pathogens in check. But rapid evolution should come at a cost. Most mutations are deleterious, so constant mutation during every cell division, coupled with unchecked proliferation, should be a recipe for disaster. How B cells somehow rapidly mutate and improve all at once was a long-standing mystery.  Now, advanced imaging techniques reveal the ...

Hyperuricemia (HU) is a metabolic disorder characterized by elevated uric acid (UA) levels in the bloodstream, commonly diagnosed when UA levels exceed 420 µmol/L (7 mg/dL) in men and 350 µmol/L (6 mg/dL) in women. Unlike other mammals, humans lack uricase, an enzyme that breaks down UA into a more soluble form, making them more susceptible to HU. The condition is influenced by genetic, dietary, and environmental factors, with contributors including purine-rich foods, metabolic dysfunctions, obesity, and ...

To uncover what drives sexual behavior in animals, researchers studied the brain activity of male mice throughout the series of actions involved in sex leading up to ejaculation. Their results, publishing in the Cell Press journal Neuron on March 19, show that the intricate dance in the brain area responsible for pleasure between two chemicals—dopamine and acetylcholine—controls the progression of sexual behavior. These findings could inspire treatments for disorders like premature ejaculation.   “Sexual behavior is a complex sequence of events,” says senior author Qinghua Liu of the National ...

About The Study: Although access to prescription stimulants is essential to addressing important clinical needs of patients with attention-deficit/hyperactivity disorder (ADHD), this study found that among U.S. adults ages 18 to 64 using prescription stimulants, one-fourth reported misuse, and nearly one-tenth had prescription stimulant use disorder. The findings may suggest potential progress in addressing the mental health care gap for middle-aged women and the need for evidence-based clinical guidance and training on benefits ...

About The Study: There is unlikely to be an increase in the very low incidence of suicide-related adverse events among individuals receiving glucagon-like peptide 1 receptor agonists (GLP-1 RAs) within the context of randomized clinical trials. While these findings may further ease concerns about these adverse effects, continued monitoring is warranted to identify particular patients who may be at risk as extended use of GLP-1 RAs expands.  Corresponding Author: To contact the corresponding author, Sean P. Heffron, MD, MS, MSc, email sean.heffron@nyulangone.org. To access the embargoed study: ...

Researchers at the Francis Crick Institute have found that the small intestine grows in response to pregnancy in mice. This partially irreversible change may help mice support a pregnancy and prepare for a second. The organs of many female animals are remodelled by reproduction, but the underlying mechanisms behind the response of the gut to pregnancy have only recently begun to be investigated. For example, scientists previously identified that the fruit fly gut expands during reproduction. In research published today in Cell, the same team found that pregnant mice had a longer small intestine from just seven days ...

Heavy alcohol consumption is a leading cause of gastrointestinal diseases, with binge drinking linked to increased intestinal permeability—a condition commonly known as "leaky gut." Despite the significant health impact of alcohol-associated gastrointestinal disorders, effective pharmacological treatments remain limited. A new study published in eGastroenterology explores the role of gut cannabinoid receptor 1 (CB1R) in alcohol binge-induced intestinal permeability and reveals how its inhibition can help protect the gut barrier. The research, conducted by scientists from the National Institute ...

Environmental conditions can cause damaging stress to plants, posing challenges for home gardeners and farmers. Therefore, early detection — before leaves visibly discolor, wilt or wither — is crucial. Now, researchers reporting in ACS Sensors have created a wearable patch for plants that quickly senses stress and relays the information to a grower. The electrochemical sensor attaches directly to live plant leaves and monitors hydrogen peroxide, a key distress signal. Pests, drought, extreme temperatures and infections all cause stress ...

BUFFALO, NY, March 19, 2025 — For the third year the American Heart Association, a global force changing the future of health for all, and the Buffalo Bills are working together to bring compression-only cardiopulmonary resuscitation (CPR), known as Hands-Only CPR and automated external defibrillator (AED) training and equipment to community events, organizations and youth sports groups across Western New York. Known in the community as the HeartBEAT initiative, this work is adding more people to the ...

CHAMPAIGN, Ill. — Campylobacter infections are the most common foodborne illnesses in the U.S., sickening an estimated 1.5 million people each year. A new study examined records of Campylobacter jejuni infections from 10 states, plotting regional, age-related, and drug-resistance trends from 2013 to 2019. The study found that drug-resistant C. jejuni infections were highest in the 20-39 age group and that quinolone-resistant C. jejuni infections increased from 22.6% of those tested in 2013 to 33.54% in 2019. The researchers also identified regional differences in C. jejuni resistance to quinolones and six other classes of antibiotics. The new findings are reported in ...

Covering a vast sky area in three mosaics, the data release also includes numerous galaxy clusters, active galactic nuclei and transient phenomena. This first survey data unlocks a treasure trove of information for scientists to dive into and tackle some of the most intriguing questions in modern science. Euclid enables us to explore our cosmic history and the invisible forces shaping our universe. With its exceptionally large field of view for a space telescope, capturing an area 240 times larger in a single shot than the Hubble Telescope, Euclid delivers outstanding image quality in both the visible and infrared light spectrum. Crucial contributions from Germany Euclid is particularly ...

The invasive Pacific oyster have adapted to life in less salty seas and are reproducing off the coast of Skåne, although having been there for less than ten years. This discovery by researchers from the University of Gothenburg suggests that the oysters could colonise the western Baltic Sea in the future. Pacific oysters were imported to oyster farms in Europe in the 1970s to replace native oysters whose stocks had collapsed. But they quickly began to spread from the farms, reaching northern ...

The latest advance in wearable robotic technology promises to solve a 200-year-old problem by revolutionising the fit of prosthetic limbs, transforming the lives of millions of amputees worldwide. The new material, ‘Roliner,’ offers amputees the power to change the shape, volume, and stiffness of the liner that is used to attach a prosthetic limb’s socket to a residual leg. Amputees could make these tweaks using their smartphone in real-time, providing a more comfortable and personalised fit. After eight years of prototype development and clinical investigation, researchers at the Department of Bioengineering at Imperial College ...

Electronic cigarettes use may pose lower cardiovascular risks in people living with HIV compared to tobacco cigarette use, new UCLA-led research shows. The study, published in JAHA, uses a novel laboratory model to examine the early stages of atherogenesis—the buildup of fats and cholesterol in the arteries. The findings suggest that electronic cigarettes (ECs) have a lower likelihood of causing changes associated with atherogenesis, compared to tobacco cigarettes (TCs), among those living with HIV.    While smoking has dropped to all-time low levels in the U.S., this hasn’t been the case for people living ...

Toronto, Canada – Every year, millions of family members and friends provide care for loved ones undergoing cancer treatment, often at great emotional cost. A new scoping review, published this week in Archives of Geriatrics and Gerontology Plus, confirms the toll that this work can take on caregivers’ mental health. According to the review, most studies show that more than 15% of those who care for loved ones with cancer suffer from post-traumatic stress disorder (PTSD). “Caregivers remain largely overlooked in psychosocial oncology care, leaving many without the support they need,” says lead author Elizaveta Klekovkina, ...

Using seawater, electricity and carbon dioxide (CO2), Northwestern University scientists have developed a new carbon-negative building material. As Earth’s climate continues to warm, researchers around the globe are exploring ways to capture CO2 from the air and store it deep underground. While this approach has multiple climate benefits, it does not maximize the value of the enormous amounts of atmospheric CO2. Now, Northwestern’s new strategy addresses this challenge by locking away CO2 permanently and turning it into valuable materials, which can be used to manufacture concrete, cement, plaster and paint. The process to generate ...

The ocean can be harnessed to absorb carbon dioxide from the atmosphere, effectively storing it in water layers and acting as a carbon sink. In research published in Advanced Sustainable Systems, investigators optimized an electrochemical method called seawater splitting for trapping and sequestering carbon dioxide into stable solid mineral deposits.  When applying voltage or current to seawater during seawater splitting, or electrolysis, hydrogen gas evolves at the cathode, while oxygen or chlorine gas is generated at the anode. Deposits of carbon-trapping minerals ...

Some individuals who have had anterior-cruciate-ligament reconstruction (ACLR), the kind of surgery often performed on athletes’ knees, may develop early-onset knee osteoarthritis. A new study in the Journal of Orthopaedic Research indicates that altered knee joint movement after ACLR could be a contributing factor.  The study used a unique dynamic X-ray imaging system to accurately measure knee joint movement during walking in people who had undergone ACLR surgery and those with healthy knees. Compared with healthy controls, ACLR patients had a higher vertical position of the patella and a higher location of articular contact between the patella and the ...

Flowers can produce showy displays that appeal to pollinating insects or animals, but some “cheat” by enticing pollinators but not rewarding them with nectar. Research in New Phytologist indicates that the tendency of flowers to be “honest” and reward pollinators with nectar is partly genetic, meaning that it can be passed down through generations.  In the study, researchers investigated floral honesty in the Mexican endemic Turnera velutina (Passifloraceae), analyzing multiple genetically distinct plants ...

Monica Wojcik, MD, MPH, FAAP, FACMG is the recipient of the ACMG Foundation for Genetic and Genomic Medicine’s 2025 Dr. Michael S. Watson Genetic and Genomic Medicine Innovation Award—the “Watson Award”—named for the American College of Medical Genetics and Genomics’ first and longstanding executive director, Michael S. Watson, MS, PhD, FACMG. “I am incredibly thrilled and humbled to receive this award, and I hope that my career will continue to honor the legacy of Dr. Watson, towards a future where all families can receive the care that they want and need, empowered by genetics and genomics,” said Dr. Wojcik. “The ...

Kiely N. James, PhD, FACMG is the recipient of the 2025 Richard King Trainee Award. This award was instituted by the ACMG Foundation for Genetic and Genomic Medicine to encourage American Board of Medical Genetics and Genomics (ABMGG), international equivalents, or genetic counseling trainees in their careers and to foster the publication of the highest quality research in Genetics in Medicine (GIM), an official journal of the ACMG. Each year the editorial board reviews all articles published in GIM by eligible trainees who were either a first or corresponding author during that year. The manuscript considered to have the ...

Each year, the ACMG Foundation for Genetic and Genomic Medicine grants its Next Generation Fellowship awards to promising early career professionals in a range of medical genetics and genomics specialties including Clinical Genetics, Clinical Biochemical Genetics, Laboratory Genetics and Genomics, Medical Biochemical Genetics and Ophthalmic Genetics. Support for this year’s class of fellows was generously provided by Bionano, Pfizer, Sanofi, Spark Therapeutics, and Takeda. The ACMG Foundation depends on corporate donations ...

Sensors attached to animals gather valuable data to track and mitigate the human influence on marine life. The Kobe University review paper emphasizes the importance of integrating data from various sources and advocates for an “Internet of Animals” based on open access and shared standards. Humanity influences marine life through a broad range of activities, spanning from fishing and pollution to noise from boats, construction and mining. To enable a sustainable life together, we need to monitor the influence of our activities on marine life and use this ...

Dr. Han Joong Tark's team at KERI's Nano Hybrid Technology Research Center has successfully fabricated ‘functional wires’, which are the foundation of wearable electronic devices, by directly applying the existing synthetic fiber processing methods. Wearable electronic devices, which can be attached to or worn on the body, such as on the wrist, ear, or eyes, have long become a part of our daily lives in various forms like smartwatches, glasses, and earphones. The key to these devices is that they must be lightweight while maintaining long-lasting performance. While there have been various efforts to achieve this, one of the most important elements is the conductive ...