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Pancreatic cancer spreads to liver or lung thanks to this protein

2025-06-03
FOR IMMEDIATE RELEASE Media Contact: Levi.Gadye@ucsf.edu, (415) 502-6397 Subscribe to UCSF News A protein called PCSK9 determines how pancreatic cancer cells metastasize to different parts of the body.   Scientists at UC San Francisco have discovered how pancreatic cancer cells thrive in the lungs or liver, environments that are as distinct to cells as the ocean and desert are to animals. The spread of cancer cells to organs like these often produces the very first symptoms of pancreatic ...

Eating an array of smaller fish could be nutrient-dense solution to overfishing

2025-06-03
ITHACA, N.Y. - To satisfy the seafood needs of billions of people, offering them access to a more biodiverse array of fish creates opportunities to mix-and-match species to obtain better nutrition from smaller portions of fish. The right combination of certain species can provide up to 60% more nutrients than if someone ate the same quantity of even a highly nutritious species, according to an analysis by Cornell University researchers. “This research hopefully highlights the importance of biodiversity, not just because of a moral quandary that we’re causing a mass extinction on Earth, but also because biodiversity can lead to better outcomes ...

Han studying potential of next generation telepresence

2025-06-03
Bo Han, Associate Professor, Computer Science, College of Engineering and Computing (CEC), received funding for: “I-Corps: Translation Potential of Next Generation Telepresence Enriched by Immersive Technologies.” Han aims to conduct extensive customer discovery and assess the value and potential of next-generation telepresence enriched by immersive technologies.  He will conduct interviews focused on three main customer segments: (1) education and training, (2) healthcare, and (3) fashion design. ...

Emory study finds molecular link between air pollution and pregnancy risks

2025-06-03
A new study by Emory University researchers, published Thursday in Environmental Science & Technology, found that exposure to the tiny particles in air pollution during pregnancy can disrupt maternal metabolisms, altering key biological pathways. These changes were associated with increased risk of various negative birth outcomes, including premature birth. The study, which analyzed blood samples provided by 330 pregnant women from the Atlanta metropolitan area, is believed to be the first to investigate how exposure to ambient fine particulate matter (PM2.5) commonly found in air pollution ...

Controlling bacteria with light: from tackling antibiotic resistance to “bacterial robots”

2025-06-03
A groundbreaking technique developed by Politecnico di Milano researchers is enabling scientists to control specific bacterial functions using light-sensitive materials. The Engineering Of bacteria to See light (EOS) project, funded by the European Research Council (ERC), has pioneered a system that allows bacteria to sense light and convert light energy into electrical signals across their membranes without the need for any genetic modification. This method is being explored as a promising solution to the growing global challenge of antibiotic resistance. Its potential applications include ...

Johns Hopkins study shows how scientists can use black holes as supercolliders

2025-06-03
As federal funding cuts impact decades of research, scientists could turn to black holes for cheaper, natural alternatives to expensive facilities searching for dark matter and similarly elusive particles that hold clues to the universe’s deepest secrets, a new Johns Hopkins study of supermassive black holes suggests. The findings could help complement multi-billion-dollar expenses and decades of construction needed for research complexes like Europe’s Large Hadron Collider, the largest and highest-energy particle accelerator in the world. “One of the great hopes for particle colliders like the Large Hadron Collider is that ...

Being incarcerated and living in areas where more have gone to jail is associated with higher death rates

2025-06-03
Journal: JAMA Network Open Title: Elevated death rates associated with incarceration emphasize the need for health care interventions both during and after incarceration Author: Utsha Khatri, MD, Assistant Professor of Emergency Medicine, Population Health Science and Policy, and Global Health and Health System Design, at the Icahn School of Medicine at Mount Sinai Bottom line: This study shows individual incarceration rates and rates at the county level (the number of incarcerated individuals per 100,000 residents) are strongly associated with ...

New insights into long-term dysfunction of edited blood stem cells and how to overcome it

2025-06-03
Scientists at the San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), Milan, have found that gene editing using CRISPR-Cas9 in combination with AAV6 vectors can trigger inflammatory and senescence-like responses in blood stem cells, compromising their long-term ability to regenerate the blood system. The study, published in Cell Reports Medicine, outlines new strategies to overcome this hurdle, improving both the safety and efficacy of gene-editing-based therapies for inherited blood disorders. The research was led by Dr. Raffaella Di Micco, group leader at SR-Tiget, New York Stem Cell Foundation Robertson Investigator and Associate Professor at the School ...

Severe maternal morbidity by race and ethnicity and birth mode

2025-06-03
About The Study: In this cross-sectional study of births among individuals with a prior cesarean birth, patterns of severe maternal morbidity (SMM) by birth mode varied by race and ethnicity, with elevated rates of SMM among those from marginalized racial and ethnic groups with planned cesarean births. Future work should identify interventions to improve quality of care and promote equity for this population. Corresponding author: To contact the corresponding author, Laura B. Attanasio, Ph.D., email lattanasio@umass.edu. To access ...

Individual- and area-level incarceration and mortality

2025-06-03
About The Study: In this cohort study of 3.26 million individuals in the U.S., results highlighted the dual burden of incarceration on health outcomes. Individuals who were incarcerated faced significantly higher risks of death, particularly from overdoses, and elevated county incarceration rates exacerbated individual-level mortality risks. These findings suggest the need for reforms in criminal justice and public health policies to address these elevated risks and their widespread implications. Corresponding author: To contact the corresponding author, Utsha G. Khatri, M.D., M.S., email utsha.khatri@mountsinai.org. To access the embargoed study: ...

New tool to generate aneuploidies and analyze their impact on development

2025-06-03
Barcelona, 3 June 2025 - More than 80% of early human embryos contain cells with an incorrect number of chromosomes—a phenomenon called aneuploidy. This typically stems from errors in chromosome segregation during the very first cell divisions. Remarkably, aneuploid cells are eliminated before implantation. When this does not happen, aneuploidy causes miscarriages or developmental disorders. Understanding how aneuploid cells are eliminated in these early stages is crucial for gaining insights into fertility, and it could also have implications for diseases like cancer. A team led by Dr. Marco Milán at IRB Barcelona has developed a tool that can generate customized ...

SwRI-led research finds particles energized by magnetic reconnection in the nascent solar wind

2025-06-03
SAN ANTONIO — June 3, 2025 — New research led by a Southwest Research Institute scientist identified a new source of energetic particles near the Sun. These definitive observations were made by instruments aboard NASA’s Parker Solar Probe, which detected the powerful phenomena as the spacecraft dipped in and out of the solar corona. These new results offer fresh perspectives on how magnetic reconnection could heat the solar atmosphere, which then transitions into the solar wind, and also how solar flares accelerate a small fraction of charged particles to ...

Aging increases brain’s sensitivity to hypoxia and blood-brain barrier damage in mice

2025-06-03
“As advanced age is associated with increased incidence of hypoxia-associated conditions such as asthma, emphysema, ischemic heart disease, heart failure, and apnea, our findings have important implications for many people.” BUFFALO, NY — June 3, 2025 — A new research paper was published in  Aging (Aging-US) on May 1, 2025, as the cover of Volume 17, Issue 5, titled “Defining the hypoxic thresholds that trigger blood-brain barrier disruption: the effect of age.” In this ...

Eating more phytosterols could lower your risk of heart disease and diabetes

2025-06-03
Heart disease and type 2 diabetes rank among the leading causes of death and disability in the United States, and eating a healthy diet rich in plant-based foods can help to prevent or delay both of these conditions. New research suggests that a particular component of plant-based foods, known as phytosterol, could be instrumental in lowering the risk.   According to the study, people who consumed more phytosterol—a compound structurally similar to cholesterol found in some plant foods—had a significantly lower risk of both heart disease and type 2 diabetes. Higher phytosterol intake was also associated with markers of better insulin regulation and reduced inflammation, ...

Eating more sweet food may not sway sweet preference

2025-06-03
Turns out, your sweet tooth may not be shaped by your diet. Findings from a new randomized controlled trial suggest that eating more sweet-tasting foods doesn’t increase someone’s preference for sweet tastes.   The researchers found that after six months on diets with varying amounts of sweet foods, study participants' preference for sweetness stayed the same, no matter how much sweet-tasting foods they ate.   “We also found that diets with lower or higher dietary sweetness ...

Scientists propose new approach for classifying processed foods

2025-06-03
Recent years have seen growing scrutiny and debate around processed foods, but researchers have struggled to pin down what aspects of food processing are most relevant to health. Now, scientists have developed a system for classifying processed foods based on information about the health impacts associated with particular ingredients.   The new approach was developed by WISEcode, creator of an app that provides consumers with information about the food ingredients found in packaged goods.   “WISEcode’s approach is more nuanced and objective than previous classification ...

New study: Daily mango intake may support postmenopausal heart and metabolic health

2025-06-03
ORLANDO, Fla., June 3, 2025 – Each year, 1.3 million women enter menopause—a life stage during which heart disease risk rises significantly. Nearly half of American women are affected by cardiovascular disease, and since women spend up to 40% of their lives postmenopausal, managing heart health is especially important. A new study published in the Journal of the American Nutrition Association found that eating about two servings of mangos daily for two weeks (330 g, about 1.5 cups) significantly ...

Study finds daily cup of beans boosts heart and metabolic health

2025-06-03
A new study suggests that regularly eating a cup of beans a day may offer measurable benefits for heart and metabolic health. Incorporating beans into daily diets could serve as a simple, cost-effective way to reduce the risk of chronic diseases.   The 12-week study of 72 people with prediabetes showed an association between chickpea consumption and improved cholesterol levels, while eating black beans was linked with reduced inflammation.   "Individuals with prediabetes often exhibit ...

Freshwater fish in US carry introduced human-infecting parasites

2025-06-03
More than 90% of popular freshwater game fish in Southern California contained an introduced parasite capable of infecting humans, according to a new study from researchers at UC San Diego’s Scripps Institution of Oceanography.  The parasites found in the study — two species of flatworms called trematodes — typically cause gastrointestinal problems, weight loss or lethargy when they infect humans. In some rare and severe cases, the parasites have caused strokes or heart attacks. The findings, published June 3 in the Journal of ...

Sanaria reports positive initial safety results for groundbreaking PfSPZ-LARC2 malaria vaccine

2025-06-03
Safety Monitoring Committee Clears Clinical Trial to Advance to Younger Age Groups Physician-scientists at Groupe de Recherche Action en Santé (GRAS) in Burkina Faso have successfully completed initial safety evaluations in 30 adult Burkinabés as the first phase of a clinical trial of Sanaria® PfSPZ-LARC2 Vaccine, which is designed to prevent infection with Plasmodium falciparum malaria. The clinical trial is being conducted in collaboration with Sanaria Inc., Seattle Children’s Research Institute (SCRI) and ...

FAU study explores barriers and trends in cannabis use disorder treatment

2025-06-03
As cannabis becomes more potent and widely used in the United States – especially among young adults – concerns about cannabis use disorder are growing. More than 16 million Americans meet the criteria, yet most never receive treatment. Despite the scale of the issue, we know surprisingly little about who gets help and why so many don’t. This treatment gap raises urgent questions about access, awareness and stigma. As laws and attitudes around cannabis shift, understanding the real-world barriers ...

Semi-automated manufacturing process for cost-efficient quantum cascade laser modules

2025-06-03
Resonantly tunable quantum cascade lasers (QCLs) are high-performance laser light sources for a wide range of spectroscopy applications in the mid-infrared (MIR) range. Their high brilliance enables minimal measurement times for more precise and efficient characterization processes and can be used, for example, in chemical and pharmaceutical industries, medicine or security technology. Until now, however, the production of QCL modules has been relatively complex and expensive. The Fraunhofer Institute for Applied Solid State Physics IAF has therefore developed a semi-automated process ...

First direct observation of the trapped waves that shook the world

2025-06-03
In September 2023, a bizarre global seismic signal was observed which appeared every 90 seconds over nine days – and was then repeated a month later. Almost a year later, two scientific studies proposed that the cause of these seismic anomalies were two mega tsunamis which were triggered in a remote East Greenland fjord by two major landslides which occurred due to warming of an unnamed glacier. The waves were thought to have become trapped in the fjord system, forming standing waves (or seiches) that undulated back and forth, causing the mystery signals. However, ...

New mRNA vaccine is more effective and less costly to develop, Pitt study finds

2025-06-03
EMBARGOED FOR RELEASE UNTIL 5:00 A.M. ET, TUESDAY, JUNE 3, 2025  New mRNA Vaccine is More Effective and Less Costly to Develop, Pitt Study Finds PITTSBURGH, JUNE 3, 2025 – A new type of mRNA vaccine is more scalable and adaptable to continuously evolving viruses such as SARS-CoV-2 and H5N1, according to a study by researchers at University of Pittsburgh School of Public Health and the Pennsylvania State University. The study was published today in npj Vaccines.   Though highly effective at inducing an immune response, current mRNA vaccines, such as those used to prevent COVID-19, present two significant challenges: the high amount of mRNA needed ...

DNA floating in the air tracks wildlife, viruses — even drugs

2025-06-03
Dublin is known as a city where you can enjoy a few pints of Guiness, get a warm welcome from the locals and hear lively traditional music drifting out of pubs and into the city air. But it’s not just music floating on the breeze. The air of Dublin also contains cannabis, poppy, even magic mushrooms — at least their DNA. That’s according to a new study that reveals the power of DNA, vacuumed up from the air, which can track everything from elusive bobcats to illicit drugs. “The level of ...
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