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Science 2026-02-26

Donation After Circulatory Death Now Dominates at Nearly Half of U.S. Organ Procurement Organizations

A study published in JAMA found that donation after circulatory death now represents approximately half of all deceased organ donors in the United States, comprising the majority of donors at 44% of organ procurement organizations. Contemporary DCD donors are more medically complex than those from earlier eras, requiring ongoing development of best practices for organ selection and preservation.
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Medicine 2026-02-26

A Single Molecular Switch Programs Immune Cells to Protect Multiple Organs

Researchers at the University of Liege discovered that the transcription factor MafB acts as a conserved genetic switch that guides monocytes into fully functional tissue macrophages across species. Without MafB, macrophages remain immature and fail to perform protective functions in the spleen, lungs, intestines, and kidneys.
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