New research to be presented at this year’s European Congress on Obesity (ECO 2025, Malaga, Spain, 11-14 May) shows that having an overweight or obesity trajectory during childhood is associated with an increased risk of chronic obstructive pulmonary disease (COPD) in adulthood. The study is by Frida Richter and Professor Jennifer Lyn Baker of The Center for Clinical Research and Prevention, Copenhagen University Hospital - Bispebjerg and Frederiksberg, The Capital Region of Denmark, Copenhagen, Denmark, and colleagues. Attention towards risk factors for COPD other than smoking is increasingly ...

Researchers at Indiana University and Wuhan University in China have unveiled a groundbreaking chemical process that could streamline the development of pharmaceutical compounds, chemical building blocks that influence how drugs interact with the body. Their study, published in Chem, describes a novel light-driven reaction that efficiently produces tetrahydroisoquinolines, a group of chemicals that play a crucial role in medicinal chemistry. Tetrahydroisoquinolines serve as the foundation for treatments targeting Parkinson’s disease, cancer, and cardiovascular disorders. These compounds are commonly found in medications such ...

Ten years ago, nobody knew that Asgard archaea even existed. In 2015, however, researchers examining deep-sea sediments discovered gene fragments that indicated a new and previously undiscovered form of microbes. With computer assistance, the researchers assembled these fragments like puzzle pieces to compile the entire genome. It was only then that they realised they were dealing with a previously unknown group of archaea. Like bacteria, archaea are single-celled organisms. Genetically, however, there are significant differences between the two domains, especially regarding their cell envelopes and metabolic processes. After ...

COLUMBUS, Ohio – If you’ve ever noticed how memories from the same day seem connected while events from weeks apart feel separate, a new study reveals the reason: Our brains physically link memories that occur close in time not in the cell bodies of neurons, but rather in their spiny extensions called dendrites. This discovery stems from studies in mice, in which researchers observed memory formation using advanced imaging techniques, including miniature microscopes that captured single-cell resolution in live animals. The study shows that memories are stored in dendritic compartments: When one memory forms, the affected ...

In a new case study, researchers from North Carolina State University found Bartonella henselae, Babesia odocoilei and Babesia divergens-like MO-1 DNA in brain tissue samples from a young child with seizures and suspected Rasmussen’s encephalitis. The findings further support the idea that these pathogens can be a cofactor in complex neurological illnesses. Bartonella are a group of vector-borne bacteria transmitted primarily via arthropods like fleas, lice and potentially ticks, but also by the animals that harbor them. Of the (at least) 45 currently known Bartonella species, ...

Patients hoping for a kidney transplant must first undergo a battery of medical tests to determine whether they are suitable candidates for the procedure and healthy enough to take post-transplant immunosuppressant drugs to prevent organ rejection. In most transplant centers, the burden falls on the patient to arrange tests like cardiac catheterization, CT scans, mammograms or colonoscopies, which can year or more to complete, meaning some people never complete the process, while others get sicker or die. But a new study published in JAMA Internal Medicine led by a University of New Mexico Health Sciences researcher demonstrates that a “concierge” ...

FOR IMMEDIATE RELEASE Key Takeaways: Bacteria get invaded by viruses called phages. Scientists are studying how bacteria use CRISPR to defend themselves from phages, which will inform new phage-based treatments for bacterial infections that are resistant to antibiotics. Bacteria seize genetic material from weakened, dormant phages and use it to form a biological “memory” of the invader that their offspring inherit and use for anti-phage defense. Like people, bacteria get invaded by viruses. In bacteria, the viral invaders are called bacteriophages, ...

As of early 2025, tuberculosis cases are increasing in the U.S. This disease, often shortened to TB, causes significant lung damage and, if not treated, is almost always lethal. World TB Day on March 24 raises awareness about the disease and commemorates Robert Koch’s discovery of the source bacterium Mycobacterium tuberculosis. More than a century later, scientists continue refining TB diagnosis methods and treatment strategies, some of which are in these four ACS journal articles. Reporters can request free access to these papers by emailing newsroom@acs.org.  Fluorescence ...

 March 19, 2025 — Today, the Obesity Action Coalition (OAC) and The Obesity Society (TOS) sent a letter to the U.S. Food & Drug Administration (FDA), along with more than 20 leading organizations and providers across the healthcare continuum, urging the agency to enforce federal regulations around compounding following the recent resolution of GLP-1 medicine shortages. Among the signatories include: the Alliance for Women’s Health & Prevention, the Association of Black Cardiologists, the National Hispanic Medical Association and the National Consumers League.  The letter follows recent announcements from the FDA that Eli Lilly’s ...

AMR occurs when disease-causing bacteria, viruses, fungi and parasites (pathogens) are no longer affected by the medicines that have been developed to target them. Drug-resistant pathogens can cause infections that are difficult or impossible to treat; they increase the risk of disease spread and can lead to severe illness, disability and death. Wastewater is commonly contaminated with antimicrobial resistant micro-organisms and antimicrobial compounds. Upon entering our environment, such as rivers and seas, contaminated wastewater therefore serves as a pathway for, and major contributor to, the spread of AMR in the UK and ...

The end of a romantic relationship usually does not come out of the blue but is indicated one or two years before the breakup. As the results of a psychological study have demonstrated, the terminal stage of a relationship consists of two phases. First, there is a gradual decline in relationship satisfaction, reaching a transition point one to two years before the dissolution of the relationship. "From this transition point onwards, there is a rapid deterioration in relationship satisfaction. Couples in question then move towards separation," said Professor ...

In a groundbreaking study on the synthesis of cellulose – a major constituent of all plant cell walls – a team of Rutgers University-New Brunswick researchers has captured images of the microscopic process of cell-wall building continuously over 24 hours with living plant cells, providing critical insights that may lead to the development of more robust plants for increased food and lower-cost biofuels production. The discovery, published in the journal Science Advances, reveals a dynamic process never seen before and may provide practical applications for everyday products derived from plants including ...

A research team led by Mount Sinai has uncovered mechanisms of abnormal immune cell function that may lead to Crohn’s disease, according to findings published in Science Immunology on March 21. The researchers said their discovery provides better understanding of disease development and could inform the development and design of new therapies to prevent inflammation before it starts in the chronic disorder. Crohn’s disease is an inflammatory bowel disease (IBD) that causes chronic inflammation of the gastrointestinal (GI) tract, and symptoms can include abdominal ...

A liquid robot capable of transforming, separating, and fusing freely like living cells has been developed. Seoul National University College of Engineering announced that a joint research team led by Professor Ho-Young Kim from the Department of Mechanical Engineering, Professor Jeong-Yun Sun from the Department of Materials Science and Engineering, and Professor Keunhwan Park from the Department of Mechanical, Smart, and Industrial Engineering at Gachon University has successfully developed a next-generation ...

Freshwater ecosystems require adequate oxygen levels to sustain aerobic life and maintain healthy biological communities. However, both long-term climate warming and the increasing frequency and intensity of short-term heatwaves are significantly reducing surface dissolved oxygen (DO) levels in lakes worldwide, according to a new study published in Science Advances. Led by Prof. SHI Kun and Prof. ZHANG Yunlin from the Nanjing Institute of Geography and Limnology of the Chinese Academy of Sciences, in collaboration with researchers from the Nanjing University and the UK’s ...

Peking University, March 19, 2025: The research group led by Prof. Wang Chu from the College of Chemistry and Molecular Engineering at Peking University published a research article entitled “Quantitative Chemoproteomics Reveals Dopamine’s Protective Modification of Tau” in Nature Chemical Biology (DOI:10.1038/s41589-025-01849-9). Using a novel quantitative chemoproteomic strategy, the team uncovered a protective role of dopamine (DA) in regulating the function of the microtubule-associated protein Tau. This discovery deepens our understanding of dopamine’s physiological and pathological roles in the human brain. Why it matters: 1. Dopamine, ...

A federally funded research team led by Sheri Holmen, PhD, investigator at Huntsman Cancer Institute and professor in the Department of Surgery at the University of Utah (the U), is testing a new combination drug therapy that could both treat and prevent melanoma metastasis, or spreading from its original site, to the brain.   “Once melanoma has spread to the brain, it’s very hard to treat. Metastasis to the brain is one of the main causes of death from melanoma,” says Holmen. “We wanted to find a solution to an unmet clinical need for those patients who had no other treatment options ...

Peking University, March 20, 2025: A groundbreaking study led by Li Yi, professor at the School of Life Sciences, was published in Nature on March 12, titled “Perception of viral infections and initiation of antiviral defence in rice”, uncovering a molecular mechanism by which rice cells perceive viral infections and initiate antiviral response, which significantly contributes to understanding of virus-host interactions for further disease resistance breeding. Why it matters: Viruses affecting rice, a staple food for more than half of the world population, pose ...

Russian scientists have discovered how the brain makes purchasing decisions. Using electroencephalography (EEG) and magnetoencephalography (MEG), researchers found that the brain responds almost instantly when a product's price deviates from expectations. This response engages brain regions involved in evaluating rewards and learning from past decisions. Thus, perceiving a product's value is not merely a conscious choice but also a function of automatic cognitive mechanisms. The results have been published in Frontiers in Human Neuroscience. Every day, people are faced with prices of food, technology, and services. Sometimes, a product seems overpriced, ...

As aging bodies decline, the brain loses the ability to cleanse itself of waste, a scenario that scientists think could be contributing to neurodegenerative conditions such as Alzheimer’s disease and Parkinson’s disease, among others. Now, researchers at Washington University School of Medicine in St. Louis report they have found a way around that problem by targeting the network of vessels that drain waste from the brain. Rejuvenating those vessels, they have shown, improves memory in old mice. The study, published online March 21 in the journal Cell, lays the groundwork to develop therapies for age-related cognitive decline that overcome ...

A new study on indoor extreme heat connects these two burdens to reveal how the co-occurrence of escalating energy bills and dangerously hot homes in Miami-Dade County exacerbates health and well-being risks for vulnerable households across months of the year. “Our findings help us understand which types of households are struggling with high indoor heat and high energy bills in a place like Miami, which is hot for many months of the year,” said Lynée Turek-Hankins, the lead author of the study that was conducted during her doctoral studies at the University of Miami Rosenstiel School of Marine, Atmospheric, and Earth Science and the Abess Center for Ecosystem ...

About The Study: This cohort study found that American Indian and Black individuals delivered at lower-quality hospitals than white individuals. The disparity in care between Black and white birthing individuals would have been reduced if individuals had delivered at their nearest hospital. Corresponding Author: To contact the corresponding author, Nansi S. Boghossian, PhD, email nboghoss@email.sc.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2025.1404) Editor’s ...

About The Study: In this cohort study, the presence and generosity of state refundable earned income tax credits were associated with a decrease in firearm suicide rates, supporting the growing body of literature highlighting the importance of antipoverty policies for reducing firearm suicide. Corresponding Author: To contact the corresponding author, Nicole Asa, MPH, email nasa3@uw.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2025.1398) Editor’s Note: Please see the article for additional information, ...

A study from Hiroshima University found that when people were told to imagine their virtual bodies in pain, their brains resisted the illusion of ownership. Their findings could provide insights into why some people may struggle with feeling connected to their own bodies, particularly in contexts involving depersonalization or negative physical states. The sense of body ownership—the feeling that our body belongs to us—is crucial in distinguishing ourselves from objects and responding to threats. Researchers study it using techniques like the rubber hand illusion (RHI) and full-body illusion (FBI), in which an individual is somehow ...

Peking University, March 19, 2025: A research team led by Professor Sun Qing-Feng in colloboration with Professor He Lin’s research group from Beijing Normal University has achieved orbital hybridization in graphene-based artificial atoms for the first time. Their findings, entitled “Orbital hybridization in graphene-based artificial atoms” was published in Nature (DOI: 10.1038/s41586-025-08620-z). This work marks a significant milestone in the field of quantum physics and materials science, bridging the gap between artificial and real atomic behaviors. Why it matters: 1. Quantum dots, often called artificial atoms, can mimic atomic orbitals but have not yet ...