Researchers at the Centre for Genomic Regulation found that over 200 metabolic enzymes bind directly to chromatin in human cells, with distinct patterns across cancer types. Breast cancer cells harbor oxidative phosphorylation enzymes in their nuclei that lung cancer cells lack, hinting at disease-specific metabolic strategies that could explain differences in treatment response.

Researchers at Penn State developed microscopic temperature sensors from two-dimensional materials that can be embedded directly onto computer chips. Each sensor is one square micrometer, responds in 100 nanoseconds, and exploits ion-electron coupling to deliver precise readings without draining chip performance.

Researchers at Washington University School of Medicine synthesized a gut-restricted liver X receptor agonist that prevented liver fibrosis and improved nutrient absorption in mice after small bowel resection. The compound, WUSTL0717, acts only in the intestines, avoiding the side effects that derailed earlier drugs in this class.

Scientists at the Korea Institute of Materials Science created a ceramic membrane that filters dye-contaminated wastewater at just 2 bar of pressure while letting salt ions pass through. The key innovations: a mutual doping technique that reduces sintering temperature by 300 degrees and a surface so smooth it prevents the microcracks that typically degrade membrane performance.

A team from the Dalian Institute of Chemical Physics and Tsinghua University experimentally determined the structural motifs of a cluster of 11 water molecules, revealing that a sandwich-like 5+1+5 arrangement dominates. The work fills a gap in understanding how water's hydrogen-bond network assembles.

By precisely repositioning nitrogen atoms within covalent organic frameworks, researchers at the Dalian Institute of Chemical Physics created a catalyst that produces hydrogen from water at six times the rate of its structural twin, achieving 12.1% quantum efficiency under visible light.

Researchers at the National University of Singapore identified the enzyme PTP1B as a key regulator of immunogenic cell death, a form of cancer cell death that activates the immune system. Blocking PTP1B with platinum compounds or gene silencing enhanced immune activation in colorectal cancer models.

Using cryo-EM, UC Davis researchers solved the structure of plant augmin, a protein complex that branches microtubules during cell division. The pitchfork-shaped complex is shared between plants and animals, with implications for cancer biology and crop breeding.

Hydrogen peroxide ranks among the world's top 100 industrial chemicals, but its production is centralized and its transport hazardous. A review maps advances in electrocatalysts that generate H2O2 on-site from oxygen and water via a two-electron oxygen reduction reaction.

Financial incentives reliably promote health behaviors in the short term, but evidence for effects beyond 18 months is thin. A review published in Science in One Health documents the promise and persistent pitfalls, from moral hazard to motivation crowding.

Of 273 population-level antimicrobial resistance models reviewed, 89% considered only humans, zero integrated humans, animals, and plants, and none met established modelling transparency guidelines. An international team calls for IPCC-style coordination for AMR.

The first artificial feeding platform for bush ticks uses a thin silicone membrane and defibinated cattle blood to replicate natural feeding. The system supported the full life cycle of the Asian longhorned tick without a live animal host.

Using a novel infrared spectroscopy method, Chinese researchers showed that only three water molecules are needed to separate barium from hydroxide in neutral BaOH clusters, providing the first molecular-scale picture of how alkaline species dissolve.

Many tumors depend heavily on the amino acid methionine. A new review consolidates preclinical and early clinical evidence for methionine restriction as a cancer therapy, finding it can hinder cell proliferation and enhance chemotherapy, though large trials are still needed.

Following a September 2025 White House briefing linking acetaminophen to autism and promoting leucovorin as a treatment, prescriptions for pregnant women fell 20% below expected levels and leucovorin prescriptions for children more than doubled, a Lancet study reports.

Home-based specialist palliative care reduced costs by 7,908 pounds per person and hospital-based care by 6,480 pounds per person, while improving patient quality of life in their final months, according to economic modelling published in Palliative Medicine.

An analysis of 171 AI-generated images and 400 public comments across 17 charity campaigns found that when AI visuals are introduced, discussion shifts away from the cause: only 20% of comments engaged with the humanitarian issue, while 70% focused on AI ethics.

Non-psychoactive cannabis compounds CBD and CBG reduced liver fat, triglycerides, and ceramides in mice fed a high-fat diet. The surprise: they worked partly by boosting phosphocreatine, an energy reserve the liver does not normally rely on heavily.

Mice that spent more time caring for pups also spent more time comforting stressed adults, and silencing the parenting neurons reduced helping behavior. The finding provides the first neural evidence that prosocial behavior may have evolved from parental care circuits.

The 22nd Carbon Research International Forum, held online March 11, features a keynote by soil scientist Nanthi Bolan of the University of Western Australia on whether organic carbon amendments can simultaneously boost soil health and sequester atmospheric carbon.

Plastic mulch film heated with a walnut-shell biochar catalyst at 350 degrees Celsius yielded 69% olefins in the liquid product, though higher temperatures reduced catalyst-clogging tar. The study offers a dual recycling approach for agricultural plastic and biomass waste.

Microplastic particles in farm soil create miniature ecosystems called plastispheres where viruses and bacteria interact intensely. A new review warns these interactions could spread antibiotic resistance genes but might also be harnessed to accelerate plastic degradation.

More than 60% of Americans would avoid riding in a driverless car, but a UC San Diego study reveals their concerns extend beyond crashes: 85% expect job losses in driving and delivery work, and 46% believe autonomous vehicles will worsen income inequality.

The combination of the cancer drug dasatinib and the plant-derived supplement quercetin reduced senescent 'zombie' cells, decreased inflammation, and improved kidney function in a preclinical model of diabetic kidney disease, Mayo Clinic researchers report.

Memorial Sloan Kettering researchers showed that inherited BRCA2 mutations and DNA repair defects predict which breast cancers will lose the RB1 gene and resist CDK4/6 inhibitors. A phase 3 trial is now testing PARP inhibitors as a preemptive alternative.