Our bodies are made up mostly of water. If this water is removed, our cells cannot survive, even when water is reintroduced. But some organisms can completely dry out yet return to life when rehydrated. A new study in Cell Systems helps explain how organisms can come back from desiccation (the removal of water or moisture) while others fail by looking at the cell’s proteins. In the first survey of its kind, a team of researchers profiled thousands of proteins at once for their ability to survive dehydration and ...

Embargoed for release until 5:00 p.m. ET on Monday 6 October 2025    Follow @Annalsofim on X, Facebook, Instagram, Bluesky, and Linkedin              Below please find summaries of new articles that will be published in the next issue of Annals of Internal Medicine. The summaries are not intended to substitute for the full articles as a source of information. This information is under strict embargo and by taking it into possession, media representatives are committing to the terms of the embargo not only on their own behalf, ...

New Canadian study reveals where HIV hides in different parts of the body Researchers at Western University and the University of Calgary have discovered how HIV hides in different parts of the body by embedding itself into the DNA of cells in a tissue-specific manner, offering new insights into why the virus is so difficult to eliminate and cure – even decades after infection and treatment. The study, led by Western University’s Stephen Barr and UCalgary’s Guido van Marle, reveals that HIV cloaks itself in the DNA of infected cells using unique DNA patterns in the ...

Over the last decade, poisonings and deaths linked to the use of local anesthetics have decreased. Even so, poisonings from one commonly used anesthetic, lidocaine, have increased in the United States, according to two new studies from the University of Illinois Chicago. By analyzing data from reports to national Poison Control Centers and to the Food and Drug Administration from 2010 to 2020, UIC researchers found total reports of poisonings fell 50% in that period. But poisonings from lidocaine increased more than 50% in less than half that ...

Nobody wants to admit that a lowly bumper sticker can influence their behavior. But researchers at the University of Cincinnati found that drivers were far more likely to honk after being cut off by a vehicle bearing a political bumper sticker, particularly one for the opposing political party. “Bumper stickers are a meaningful way in which partisan divides are reinforced in everyday life,” UC researchers concluded. “They have tangible impacts on road safety. Partisan bumper stickers may be mundane, but they are not trivial.” For a study published in the journal Frontiers in Political Science, UC Assistant ...

JUPITER, Fla. — In a quest to develop new antiviral drugs for COVID-19 and other diseases, a collaboration led by scientists at The Wertheim UF Scripps Institute has identified a potential new drug against the virus that causes COVID-19. In the process, the team devised a powerful new platform for finding medicines to fight many types of infectious diseases. Writing in the Journal of the American Chemical Society, in an online article posted on Monday, Oct. 6, 2025, the scientists said they began by seeking ...

A new method of taking microscopic images of a live mouse’s retina through the eye allows to record the reaction of brain cells to disease and treatment. The Kobe University development is more easily applicable than previous methods and promises to advance research on and treatment of vision-related diseases. Diabetic retinopathy, a form of diabetic eye disease, is one of the leading causes of blindness around the globe. “It’s understood that vision is lost due to damage to the blood vessels in the retina, but recent research has identified that abnormalities in neurons and immune cells begin prior to vascular damage,” says Kobe ...

Rockville, MD. (October 6, 2025) – The 2025 NFCR Global Summit and Award Ceremonies for Cancer Research & Entrepreneurship will convene an extraordinary roster of world-renowned scientists, entrepreneurs, investors, and patient advocates on October 24, 2025, at the National Press Club in Washington, D.C. This is a signature annual gathering where the leaders driving the future of oncology come together under one roof to challenge the status quo, reveal bold ideas, share insights, and spark collaborations that shape what’s next in cancer research ...

Key takeaways Internal organ tissues often don’t heal after illness or injury and lose some function, such as the heart after a heart attack. UCLA cardiologists have identified a protein that interferes with healing. Funded entirely by federal and state grants, the researchers developed a drug to block this protein and promote tissue regeneration. The FDA has now granted approval to begin Phase I clinical trials of the first-in-class drug for tissue repair, called AD-NP1, in humans. The body’s tissues can get injured in many ways, but while some injuries ...

Neuroinflammation damages neurons and can contribute to diseases like Alzheimer’s. Cannabidiol (CBD) has anti-inflammatory properties, which suggests that it could combat neuroinflammation in Alzheimer’s. In a new eNeuro paper, Babak Baban and colleagues, from Augusta University, explored whether CBD can be leveraged as an antiinflammatory treatment in an established Alzheimer’s disease mouse model.    The researchers assessed two distinct mechanisms for shaping immune responses and regulating neuroinflammation ...

Images Spirals of solar wind can spin off larger solar eruptions and disrupt Earth's magnetic field, yet they are too difficult to detect with our current single-location warning system, according to a new study from the University of Michigan.    But a constellation of spacecraft, including one that sails on sunlight, could help find the tornado-like features in time to protect equipment on Earth and in orbit. The study results come from computer simulations of a massive cloud of plasma erupting from the sun and moving through the solar system. Because the simulation covers features that span ...

The selection of patients for allo-HSCT and the best approach to bridging patients to transplantation is continuously discussed by experts. The first results of the ASAP study (ASAP standing for “as soon as possible”), published in 2024, have already attracted considerable attention [2]. ASAP questions existing treatment standards for AML and was the first randomized controlled trial to compare remission induction with salvage chemotherapy prior to allo-HSCT – which represents ...

In a recent study published in Cell Metabolism, a collaborative research team led by Chen-Yu Zhang, Xi Chen, and Di-Jun Chen from Nanjing University, together with Tao Zhang from Nanjing Medical University, reported groundbreaking findings in their paper entitled “Paternal exercise confers endurance capacity to offspring through sperm microRNAs.” This research provides the first evidence that sperm microRNAs act as carriers of epigenetic information, enabling the intergenerational transmission of paternal ...

New artificial intelligence-generated images that appear to be one thing, but something else entirely when rotated, are helping scientists test the human mind. The work by Johns Hopkins University perception researchers addresses a longstanding need for uniform stimuli to rigorously study how people mentally process visual information. “These images are really important because we can use them to study all sorts of effects that scientists previously thought were nearly impossible to study in isolation—everything from size to animacy to emotion,” said ...

About The Study: Inhaler-related emissions in the U.S. have increased over the past decade. Policymakers and regulators seeking to reduce emissions should identify targeted solutions aimed at shifting utilization to currently marketed dry powder and soft mist inhalers while facilitating the entry of newer, affordable metered-dose products containing propellants with low global warming potential. Corresponding Author: To contact the corresponding author, William B. Feldman, MD, DPhil, MPH, email wfeldman@mednet.ucla.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jama.2025.16524) Editor’s ...

Inhalers are the frontline treatment for asthma and COPD, but they come with a steep environmental cost, according to a new UCLA Health study — the largest to date quantifying inhaler-related emissions in the United States. Researchers found that inhalers have generated over 2 million metric tons of carbon emissions annually over the past decade, equivalent to the emissions of roughly 530,000 gas-powered cars on the road each year. The study, published in JAMA, analyzed emissions from the three types of inhalers approved for asthma or COPD from 2014 to 2024. It found that metered-dose inhalers were the most ...

About The Study: In this cohort study, implementation of the sickest patients first (SIPS) surgical handover system (introduction, situation, background, assessment, recommendation; prioritize; summarize) was associated with improvements in handover quality, patient physiology, and staff perceptions of safety without prolonging handover meetings. Corresponding Author: To contact the corresponding author, Jessica M. Ryan, MB, email jessicaryan@rcsi.com. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2025.38896) Editor’s ...

About The Study: In this prospective cohort study of young adults, unfavorable patterns of cardiovascular health (CVH) change through young adulthood were associated with marked elevations in risk for incident cardiovascular disease (CVD). These data suggest that achieving and maintaining high CVH throughout young adulthood through strategies of primordial prevention are important for prevention of later-life CVD. Corresponding author: To contact the corresponding author, Donald M. Lloyd-Jones, M.D., ...

About The Study: In this cross-sectional study, nurses’ subjective workload and shift-level staffing ratios exerted direct effects on reliable care delivery. High subjective workload and staffing ratios greater than 2 infants per nurse should be targets for workload reduction in neonatal intensive care units.  Corresponding Author: To contact the corresponding author, Heather L. Tubbs-Cooley, Ph.D., email tubbscooley.1@osu.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi: 10.1001/jamapediatrics.2025.3647) Editor’s ...

The remote work debate often focuses only on leadership or the employee, but according to a new doctoral dissertation from the University of Vaasa, Finland, the prerequisites for success are found in a broader context. Johanna Jansson's research in the field of human resource management reveals that successful remote work is built on three foundations: overall organisational design, the supervisor-subordinate relationship, and the employee's own role. When these three foundations are in balance, both company ...

WASHINGTON — Researchers have created a chip-based device that can split phonons — tiny packets of mechanical vibration that can carry information in quantum systems. By filling a key gap, this device could help connect various quantum devices via phonons, paving the way for advanced computing and secure quantum communication. “Phonons can serve as on-chip quantum messages that connect very different quantum systems, enabling hybrid networks and new ways to process quantum information in a compact, scalable format,” said research team ...

HOUSTON (Oct. 6, 2025) – Researchers at Texas Children’s Neurological Research Institute (NRI) and Baylor College of Medicine have developed a powerful new tool within the Genome Aggregation Database (gnomAD) to sharpen the accuracy of genetic testing – a breakthrough with direct implications for patient diagnoses and care worldwide. The work, published in Nature Communications, applies a method called local ancestry inference (LAI), which breaks the genome into ancestry-specific segments to provide more accurate insights into genetic differences. “This research updates our genomic resources to better reflect the ...

October 6, 2025 (Washington, DC)—The Milken Institute Science Philanthropy Accelerator for Research and Collaboration (SPARC), in partnership with the Ann Theodore Foundation (ATF), today announced that the Ann Theodore Foundation Breakthrough Sarcoidosis Initiative (ATF-BSI) has awarded five grants totaling more than $2.5 million to interdisciplinary research teams. Concurrently, the two partners have launched ATF-BSI’s fifth round of philanthropic funding via a new request for proposals (RFP) related to sarcoidosis ...

Embargoed until 7 a.m. CT/8 a.m. ET, Monday, Oct. 6, 2025 DALLAS, Oct. 6, 2025 — Emelia J. Benjamin, M.D., FAHA, professor of medicine at Boston University (BU), will receive the 2025 Eugene Braunwald Academic Mentorship Award at the American Heart Association’s Scientific Sessions 2025. The meeting, to be held Nov. 7-10, 2025, in New Orleans, is a premier global exchange of the latest scientific advancements, research and evidence-based clinical practice updates in cardiovascular science. Dr. Benjamin will be recognized with the award during the Presidential Session on Sunday, Nov. 9, 2025. Named for legendary cardiologist Eugene ...

Soil contamination is a global environmental concern, with toxic metals and metalloids from industrial activities persisting as long-term pollutants. Arsenic (As), although naturally occurring, becomes widespread when mobilized by mining. Abandoned gold mines are major sources, releasing arsenic-rich minerals into surrounding environments through erosion and leaching. Forest soils, essential for ecosystem health and biodiversity, are particularly vulnerable. Despite arsenic’s mobility under specific soil conditions and known toxicity, its behavior in forest soils and impacts on soil organisms remain poorly understood. In ...