University students in five countries played economic games in rooms ranging from 18 to 34 degrees Celsius. Heat above 30 degrees increased frustration and unhappiness but had no systematic effect on sharing, selfishness, spite, or competitiveness.

The EDGCN framework achieved 86.50% and 90.14% classification accuracy and 64.04% decoding accuracy on benchmark motor imagery EEG datasets by using adaptive spatial and temporal embeddings to capture how brain activity varies between people and over time.

Two DNA aptamers, MN711 and MN734, bind neurofilament light chain at 11 nM and 8.1 nM respectively, matching commercial antibodies. Unlike antibodies, they can be chemically synthesized with minimal batch variation and modified for use on biosensor electrodes.

Researchers at Central South University trained machine learning models on radiomic features extracted from pre-surgery CT scans of 65 traumatic brain injury patients. Models using imaging data accurately predicted which patients would need a second, more invasive skull surgery.

Researchers at Sichuan University found that SMAD7, traditionally considered an inhibitor, forms a nuclear complex with beta-catenin to amplify Wnt signaling in human dental pulp stem cells, suggesting new targets for regenerative dentistry.

Polydopamine-coated titanium dioxide nanoparticles accumulated about 7,780 nanograms of calcium phosphate mineral mass versus 5,641 nanograms for zein-coated particles, a 37% difference traced to polydopamine's polar surface chemistry.

Researchers found that the call of the treefrog Gracixalus weii closely mimics the Black-Breasted Thrush's song pattern: a longer introductory note followed by two shorter notes at almost identical pitches. The resemblance has caused surveyors to undercount frog populations.

An analysis of more than 85,000 crowdsourced posts found that underground thermal complaints rise 10-27% for every degree Celsius above 10 degrees at the surface. London Underground temperatures have reached 47 degrees Celsius, exceeding the city's highest recorded air temperature.

A Rice University team used PFAS-laden activated carbon from firefighting foam to extract lithium fluoride from brine at 99% purity, recovering 82% of available lithium in minutes while using less water and energy than commercial methods.

Mock jurors were nearly 50% more likely to blame a radiologist who reviewed a CT scan only once after an AI alert, compared to one who read it twice. The finding suggests workflow design, not just AI accuracy, shapes legal risk in medicine.

Ibnova Therapeutics, a new biotech company born from Australian and Danish research collaboration, will develop stem cell-derived heart muscle therapies for heart failure, aiming for first-in-human clinical trials within three to five years based on animal studies showing restored cardiac function.

Researchers analyzing over 400 faba bean varieties found that a single gene locus containing CBF/DREB transcription factors distinguishes winter-hardy from summer varieties, with the same locus also linked to stable yields across environments, offering a clear target for breeding winter-tolerant lines.

Over ten months, AI models analyzing passive smartwatch data from 88 participants aged 45-77 predicted emotional health with 5-10% error rates and cognitive performance with 10-20% error, with air pollution, weather, and sleep variability emerging as key predictive factors.

ETH Zurich researchers created a boron-containing coupling reagent that joins protein fragments 1,000 times faster than conventional carbon-based methods, enabling automated synthesis of poorly soluble proteins including those targeted by 60% of current drugs.

OIST researchers identified 80 proteins involved in plasma membrane repair in budding yeast, tracked their movements in real time after laser-induced damage, and discovered that endocytosis plays a repair role in yeast, suggesting an ancient, conserved mechanism.

A comprehensive review from Cambridge researchers maps the translational pathway from current checklist-based psychiatric diagnosis toward biologically grounded approaches, synthesizing biomarker research, digital phenotyping, and AI while honestly cataloging the barriers that remain.

A synthesis of large-scale genomic studies reveals that common epilepsies are shaped by thousands of genetic variants, with genetic generalized epilepsy showing unusually high heritability relative to its polygenicity, making it one of the most cost-efficient targets in complex disease genomics.

Mount Sinai researchers used RNAscope to map GLP-1 expression at single-transcript resolution across the entire mouse brain, revealing that several brain nuclei show GLP-1 expression in only one sex, with implications for how semaglutide-class drugs may work differently in women and men.

Voluntary exercise in rats decreased tryptophan-metabolizing gut bacteria Alistipes and Clostridium, increased circulating tryptophan metabolites, and reduced aryl hydrocarbon receptor expression specifically in the dorsal hippocampus, tracing a coherent gut-brain pathway from running wheel to memory circuitry.

UCL researchers used single-cell calcium imaging and a dynamic neural encoding model to reconstruct 10-second video clips from mouse visual cortex activity alone, achieving high pixel-level correlation with the original footage.

Numerical models reveal that chemical weathering beneath continental ice sheets during snowball Earth events could have consumed CO2 at rates approaching volcanic emission levels, offering a new explanation for why the Sturtian glaciation lasted far longer than the Marinoan.

The Simplified Adolescent Factors for Endometriosis (SAFE) score uses six questions about pelvic pain, menstrual symptoms, and family history to identify at-risk girls and young women, aiming to cut the average 6-8 year diagnostic delay for endometriosis.

Breast cancer cells use the pressure-sensing ion channel PIEZO1 to detect physical compression within confined tissue, triggering the Rho-ROCK pathway and creating an epigenetic 'mechanical memory' that drives aggressive behavior long after the squeeze is relieved.

A new IgG ELISA assay for mpox antibodies was developed and validated at Rwanda's National Reference Laboratory during the clade 1b outbreak, using just four key antibody signatures to keep the test affordable and accessible in remote settings.

Structural changes in three blood proteins, C1QA, clusterin, and apolipoprotein B, distinguished cognitively normal adults from Alzheimer's patients with up to 93% accuracy in two-way comparisons, suggesting protein folding may offer a new diagnostic window.