Real-world study finds hydroxyurea effective long-term in children living with sickle cell disease
2025-04-17
(WASHINGTON, April 17, 2024) — Hydroxyurea remains effective long-term in reducing emergency department visits and hospital days for children living with sickle cell disease (SCD), according to new research published in Blood Advances.
“This is one of the first large, real-world, long-term studies to assess the efficacy of hydroxyurea outside of a controlled setting,” said study author Paul George, MD, a pediatric hematology/oncology fellow and PhD candidate at Emory University School of Medicine and Aflac Cancer and Blood Disorders Center at Children’s ...
FAU designated a National Center of Academic Excellence in Cyber Research
2025-04-17
Florida Atlantic University has been recognized as a National Center of Academic Excellence in Cyber Research (CAE-R) by the National Security Agency (NSA) and its partners in the National Centers of Academic Excellence in Cybersecurity (NCAE-C). This prestigious designation, awarded through the academic year 2030, affirms the university’s leadership and innovation in the field of cybersecurity research at the doctoral level.
This recognition places FAU among an elite group of institutions nationwide that have demonstrated a sustained commitment to cutting-edge research in cyber defense and security. The CAE-R designation is awarded to universities whose programs meet rigorous ...
European potato genome decoded: Small gene pool with large differences
2025-04-17
A research team has decoded the genome of historic potato cultivars and used this resource to develop an efficient method for analysis of hundreds of additional potato genomes.
Potatoes are a staple food for over 1.3 billion people. But despite their importance for global food security, breeding successes have been modest. Some of the most popular potato cultivars were bred many decades ago. The reason for this limited success is the complex genome of the potato: there are four copies of the genome in each cell instead of just two. ...
Nontraditional risk factors shed light on unexplained strokes in adults younger than 50
2025-04-17
Research Highlights:
Among adults ages 18-49 (median age of 41 years) who were born with a hole in the upper chambers of their heart known as patent foramen ovale (PFO), strokes of unknown cause were more strongly associated with nontraditional risk factors, such as migraines, liver disease or cancer, rather than more typical factors such as high blood pressure.
Migraine with aura was the top factor linked to strokes of unknown causes, also called cryptogenic strokes, especially among women.
Embargoed ...
Extreme drought contributed to barbarian invasion of late Roman Britain, tree-ring study reveals
2025-04-17
Three consecutive years of drought contributed to the ‘Barbarian Conspiracy’, a pivotal moment in the history of Roman Britain, a new Cambridge-led study reveals. Researchers argue that Picts, Scotti and Saxons took advantage of famine and societal breakdown caused by an extreme period of drought to inflict crushing blows on weakened Roman defences in 367 CE. While Rome eventually restored order, some historians argue that the province never fully recovered.
The ‘Barbarian Conspiracy’ of 367 CE was one of the most severe threats to Rome’s hold on Britain since the Boudiccan revolt three centuries earlier. Contemporary sources indicate that components ...
Antibiotic-resistant E. albertii on the rise in Bangladeshi chicken shops
2025-04-17
If you have ever chickened out of eating chicken, your unease may not have been unreasonable.
Osaka Metropolitan University researchers have detected alarming rates of Escherichia albertii, an emerging foodborne pathogen, in retail chicken meat in Bangladesh. Their findings show extensive contamination and significant antimicrobial resistance, underscoring the potential risks to public health.
E. albertii is a less known but probably not less dangerous relative of E. coli. First described in Bangladesh in 2003, this bacterium ...
Veterinary: UK dog owners prefer crossbreeds and imports to domestic pedigree breeds
2025-04-17
The UK pedigree dog population shrank by a yearly decline of 0.9% between 1990 and 2021, according to research published in Companion Animal Genetics and Health. The study highlights a rise in the populations of crossbreeds and imported pedigree dogs since 1990, but finds that only 13.7% of registered domestic pedigree dogs were used for breeding between 2005 and 2015.
There are more than 400 breeds of dogs globally, characterised by different appearances and behaviours. While the overall population of pet dogs in the UK ...
Study links climate change to rising arsenic levels in paddy rice, increasing health risks
2025-04-16
Climate change may significantly impact arsenic levels in paddy rice, a staple food for millions across Asia, reveals a new study from Columbia University’s Mailman School of Public Health. The research shows that increased temperatures above 2°C, coupled with rising carbon dioxide (CO2) levels, lead to higher concentrations of inorganic arsenic in rice, potentially raising lifetime health risks for populations in Asia by 2050. Until now, the combined effects of rising CO2 and temperatures on arsenic accumulation in rice have not been studied in detail. The research done ...
Study indicates that risky surgery after a stroke due to carotid artery stenosis is no longer necessary for majority of patients
2025-04-16
European research led by University College London (UCL), together with Amsterdam UMC and the University of Basel shows that a significant proportion of patients who suffer a stroke due to carotid artery narrowing can be treated with medication only. A risky carotid artery operation, currently still the standard treatment for many patients, may then no longer be necessary for this group of patients. This research, published today in the Lancet Neurology, may lead to the global guidelines for the treatment of these patients being adjusted.
In the Netherlands, about 2,000 people with carotid artery stenosis ...
Blood pressure: New research shows a changing climate may jeopardise global blood supply
2025-04-16
Blood pressure: New research shows a changing climate may jeopardise global blood supply
A new study published in The Lancet Planetary Health suggests a changing climate threatens the continuous availability of safe blood across the world.
Researchers at the University of the Sunshine Coast and Australian Red Cross Lifeblood say health issues, the spread of infectious disease and extreme weather exacerbated by climate change will impact the ability of people to donate, and at the same time may trigger a rise in the need for blood.
Lifeblood researcher and UniSC Adjunct Research Fellow Dr Elvina Viennet said this ...
Start of US hunting season linked to increased firearm incidents, including violent crimes and suicide
2025-04-16
The start of deer hunting season in the US - when firearms and ammunition are more available in certain states - is associated with increases in both hunting and non-hunting related firearm incidents, including violent crime and suicide, finds a study published by The BMJ today.
While increases in hunting related incidents are to be expected at this time, increases in non-hunting related firearm incidents “indicate the potential general effect of greater firearm availability on different ...
New system could help reduce unnecessary surgery to prevent strokes
2025-04-16
Researchers at UCL have tested a new scoring system to measure the risk of stroke in patients with narrowed arteries due to atherosclerosis, which could prevent unnecessary surgeries and stents.
Atherosclerosis is a condition where the blood vessels become narrowed and hardened due to the buildup of plaque, including in the carotid arteries, which carry blood from the heart to the brain. Atherosclerosis can lead to serious health problems like strokes and heart attacks.
Atherosclerosis is a very common condition that can affect anyone, particularly those over the age of 65, smokers and people with a high cholesterol, hypertension or family ...
Strongest hints yet of biological activity outside the solar system
2025-04-16
Astronomers have detected the most promising signs yet of a possible biosignature outside the solar system, although they remain cautious.
Using data from the James Webb Space Telescope (JWST), the astronomers, led by the University of Cambridge, have detected the chemical fingerprints of dimethyl sulfide (DMS) and/or dimethyl disulfide (DMDS), in the atmosphere of the exoplanet K2-18b, which orbits its star in the habitable zone.
On Earth, DMS and DMDS are only produced by life, primarily microbial life such as marine phytoplankton. While an unknown chemical process may be the source of these molecules in K2-18b’s atmosphere, the results are ...
Children face ‘lifelong psychological wounds’ from entrenched inequities made worse by pandemic, doctor warns
2025-04-16
The COVID-19 pandemic deepened existing health disparities and thrust children into a mental health epidemic, altering the landscape of health and wellbeing for a generation.
This is the stark warning of Dr Jatinder Hayre in his critical analysis of ‘entrenched inequities’ in the UK, The Lost Generation of COVID-19.
He presents a breadth of research to set out how, after a prolonged period of cuts to UK public services, Britain’s struggle with COVID-19 has fundamentally reshaped its social, economic, and health landscape. Dr Hayre, who led the Independent ...
New research reveals socio-economic influences on how the body regulates eating
2025-04-16
Published in the journal Food Quality and Preference, the research highlights how physiological signals, particularly those transmitted via the vagus nerve, interact with socio-economic factors to shape dietary behaviour.
The study involved 96 students from diverse socio-economic backgrounds who participated in a chocolate tasting session.
In a controlled laboratory setting, each participant was presented with a plate containing 70 milk chocolate pieces and invited to sample and rate them at their leisure.
Researchers measured each student's heart rate variability (HRV) as a proxy for ...
Unhealthy metabolic profile sharply increases risk of breast cancer returning and subsequent death from breast cancer among those who have survived the disease
2025-04-16
New research to be presented at this year’s European Congress on Obesity (ECO 2025, Malaga, Spain, 11-14 May) and published in The Journal of Internal Medicine shows that, in survivors of breast cancer, having an unhealthy metabolic profile or so called ‘metabolic syndrome’ increases the risk of breast cancer recurrence by 69%, and subsequent breast cancer mortality by 83%. The study is by Dr Sixten Harborg, Department of Oncology, Aarhus University/Aarhus University Hospital, Aarhus, ...
Marine radar can accurately monitor vessel speeds to protect whales, study finds
2025-04-16
A new study by researchers at ProtectedSeas highlights the potential of marine radar technology to monitor speed of small vessels. The research, aimed at testing the accuracy of radar in assessing potential violations, found that the technology could detect speed violations with 95% confidence, offering a promising solution to help reduce the threat of vessel strikes on whale populations. The analysis was recently published in the journal Sensors.
The impact of small vessels on whales is becoming a growing concern in busy marine environments due to the increasing number ...
National Center to Reframe Aging teams up with West End Home Foundation
2025-04-16
The National Center to Reframe Aging — the leading organization for proven communication strategies and tools to effectively frame aging issues — is partnering with The West End Home Foundation (WEHF), an independent charitable foundation located in Nashville, Tennessee.
The National Center to Reframe Aging will be a strategic partner to support the WEHF’s mission to enrich the lives of older people through grant making, advocacy, and community collaboration. Key leaders of the Tennessee Department of Disability and Aging and the Tennessee aging network will participate in educational opportunities and receive tools from the National Center ...
How do age, sex, hormones and genetics affect dementia biomarkers in the blood?
2025-04-16
EMBARGOED FOR RELEASE UNTIL 4:00 P.M. ET, WEDNESDAY, APRIL 16, 2025
MINNEAPOLIS — A new study has found important clues about the roles age, sex, hormonal changes and genetics play in how certain biomarkers for dementia are expressed in the blood, according to a study published on April 16, 2025, online in Neurology®, the medical journal of the American Academy of Neurology.
“Blood tests that detect biomarkers for Alzheimer's disease and other dementias are emerging and as these tests are further developed, they are becoming important tools for understanding and diagnosing ...
NSF NOIRLab astronomer discovers oldest known spiral galaxy in the Universe
2025-04-16
Large, grand-design spiral galaxies like our own Milky Way are common in the nearby Universe. But they have proven hard to find in the early Universe, which is consistent with expectations that large disks with spiral arms should take many billions of years to form. However, assistant astronomer Christina Williams of NSF NOIRLab, which is funded by the U.S. National Science Foundation, has discovered a surprisingly mature spiral galaxy just one billion years after the Big Bang [1]. This is the most distant, earliest known ...
Iron Age purple dye "factory" in Israel was in operation for almost 500 years, using mollusks in large-scale specialized manufacturing process
2025-04-16
Iron Age purple dye "factory" in Israel was in operation for almost 500 years, using mollusks in large-scale specialized manufacturing process
Article URL: https://plos.io/44elLDX
Article title: Tel Shiqmona during the Iron Age: A first glimpse into an ancient Mediterranean purple dye ‘factory’
Author countries: U.S., Israel
Funding: The author(s) received no specific funding for this work. END ...
Even vegans who get enough total protein may fall short for some essential amino acids
2025-04-16
In a new study of people with long-term vegan diets, most ate an adequate amount of total daily protein, but a significant proportion did not meet required levels of the amino acids lysine and leucine. Bi Xue Patricia Soh and colleagues at Massey University, New Zealand, present these findings in the open-access journal PLOS One on April 16, 2025.
Proteins are made up of various molecular “building blocks” known as amino acids. While the human body can synthesize most of the amino acids we need to live, we completely rely on the ...
RoboBee comes in for a landing
2025-04-16
The Harvard RoboBee has long shown it can fly, dive, and hover like a real insect. But what good is the miracle of flight without a safe way to land?
A storied engineering achievement by the Harvard Microrobotics Laboratory, the RoboBee is now outfitted with its most reliable landing gear to date, inspired by one of nature’s most graceful landers: the crane fly.
Publishing in Science Robotics, the team led by Robert Wood, the Harry Lewis and Marlyn McGrath Professor of Engineering and Applied Sciences in the John A. Paulson School ...
“Ban-the-Box” policy did not effectively help job applicants with criminal records in one analysis
2025-04-16
Analysis of job applicant data from one large employer suggests that a policy meant to improve employment prospects for people with criminal records did not actually lead to changes in job offers for people with records. Deborah Weiss of Northwestern University, U.S., and colleagues present these findings in the open-access journal PLOS One on April 16, 2025.
Parts of the U.S. have introduced “Ban-the-Box” (BTB) laws, which aim to improve job prospects for people with criminal records. ...
Sunscreen, clothes and caves may have helped Homo sapiens survive 41,000 years ago
2025-04-16
ANN ARBOR—Ancient Homo sapiens may have benefitted from sunscreen, tailored clothes and the use of caves during the shifting of the magnetic North Pole over Europe about 41,000 years ago, new University of Michigan research shows.
These technologies could have protected Homo sapiens living in Europe from harmful solar radiation. Neanderthals, on the other hand, appear to have lacked these technologies and disappeared around 40,000 years ago, according to the study, published in Science Advances and led by researchers at Michigan Engineering and the U-M Department of Anthropology.
The team found ...
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