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A financial toll on patients with type 2 diabetes

2025-07-28
Embargoed until 11 a.m. ET, July 28, 2025   In a first-of-its-kind study, researchers used a unique dataset to show that patients with type 2 diabetes have significantly worse financial outcomes than other patients.   Findings showed diabetes patients fared worse on all seven financial outcomes studied, including below-prime credit scores, medical and non-medical debt in collections, 60-plus-day delinquent debt, debt charge-offs, bankruptcy filings and foreclosure.   The diabetes patients in this study were compared to people who had a blood test ...

Safflower yellow pigments in coronary heart disease: Mechanisms, applications, and future perspectives

2025-07-28
Coronary heart disease (CHD), characterized by atherosclerosis-induced myocardial ischemia, remains a leading cause of mortality in China. Safflower yellow pigments (SYPs), the primary bioactive components of Carthamus tinctorius L., consist mainly of quinochalcone C-glycosides, with hydroxysafflor yellow A (HSYA) and anhydrosafflor yellow B (AHSYB) as key constituents. This review synthesizes evidence on SYPs' mechanisms, therapeutic applications, and future directions in CHD management. Chemical Composition and Pharmacokinetics SYPs comprise over 20 identified compounds, including HSYA and AHSYB, which confer cardiovascular protection, anti-inflammatory, and antioxidant activities. ...

TraMA: new RNA-based measure predicts mortality risk and tracks aging

2025-07-28
“TraMA is likely to be of particular value to researchers interested in understanding the biological processes underlying health and aging, and for social, psychological, epidemiological, and demographic studies of health and aging.” BUFFALO, NY — July 28, 2025 — A new research paper was published in Aging (Aging-US) Volume 17, Issue 6, on June 13, 2025, titled “Development of a novel transcriptomic measure of aging: Transcriptomic Mortality-risk Age (TraMA).” In ...

From WebMD to AI chatbots: How innovation has empowered patients to take control of their health

2025-07-28
TORONTO, ON July 28, 2025 A new research article published in the Journal of Participatory Medicine unveils how successive waves of digital technology innovation have empowered patients, fostering a more collaborative and responsive health care system. The paper, titled "From Internet to Artificial Intelligence (Al) Bots: Symbiotic Evolutions of Digital Technologies and e-Patients," explores the symbiotic evolution of digital health tools and the increasingly engaged e-patient. The concept of the e-patient, defined as an individual "equipped, enabled, empowered, and engaged" in their health, has been propelled forward by advancements spanning ...

Unravelling antileishmanial mechanisms of phytochemicals: From mitochondrial disruption to immunomodulation

2025-07-28
Leishmaniasis, a neglected tropical disease caused by Leishmania parasites, affects millions globally. Current synthetic treatments face limitations including toxicity, cost, and resistance. Phytochemicals from medicinal plants offer promising alternatives. This mini-review synthesizes preclinical mechanisms of plant-derived compounds against leishmaniasis, focusing on mitochondrial disruption, immunomodulation, and redox imbalance. Key Antileishmanial Mechanisms 1. Membrane Disruption & ...

Association for Molecular Pathology announces 2025 award recipients

2025-07-28
The Association for Molecular Pathology (AMP), the premier global molecular diagnostic professional society, today announced the recipients of its 2025 Excellence in Molecular Diagnostics, Jeffrey A. Kant Leadership and Meritorious Service Awards. These prestigious honors will be presented in November during the AMP 2025 Annual Meeting & Expo in Boston. Award for Excellence in Molecular Diagnostics Elaine R. Mardis, Ph.D. Co-executive Director, Steve and Cindy Rasmussen Institute for Genomic Medicine, Nationwide Children’s Hospital Rasmussen Nationwide Foundation Endowed Chair in Genomic ...

When light collides with light

2025-07-28
Usually, light waves can pass through each other without any resistance. According to the laws of electrodynamics, two light beams can exist in the same place without influencing each other; they simply overlap. Light saber battles, as seen in science fiction films, would therefore be rather boring in reality. Nevertheless, quantum physics predicts the effect of “light-on-light scattering”. Ordinary lasers are not powerful enough to detect it, but it has been observed at the CERN particle accelerator. Virtual particles can literally emerge from nothing for a short time, interact with the photons and change their direction. The effect is extremely small, ...

Study finds that white students visit college advisers the least, but benefit most in terms of graduation rates and GPA

2025-07-28
A new study finds that White students visit academic advisers the least, but have the highest academic benefits, in terms of GPA and graduation rates, compared to nonwhite students and international students. In higher education, substantial gaps exist between White and nonwhite students, with a greater number of White students graduating in fewer years and receiving higher grades than many other groups. Prior research shows that nonwhite students are less likely to engage with faculty members, but there is a dearth of information related to interactions with academic advisers—staffers ...

Science by the millions: How everyday people are revolutionizing global biodiversity research with tech

2025-07-28
A frog croaks from a walking trail. A hiker snaps a photo and uploads it to iNaturalist. That single act — one person, one amphibian and one click — feeds into a growing global dataset that scientists now use to map shifting species ranges, detect invasive threats and even discover new species. An international study led by researchers at the University of Florida Institute of Food and Agricultural Sciences (UF/IFAS) shows how iNaturalist, the global technology platform through which everyday people share ...

A bolt is born! Atmospheric events underpinning lightning strikes explained

2025-07-28
UNIVERSITY PARK, Pa. — Though scientists have long understood how lightning strikes, the precise atmospheric events that trigger it within thunderclouds remained a perplexing mystery. The mystery may be solved, thanks to a team of researchers led by Victor Pasko, professor of electrical engineering in the Penn State School of Electrical Engineering and Computer Science, that has revealed the powerful chain reaction that triggers lightning. In the study published today (July 28) in the Journal ...

Using alcohol to reduce the costs of industrial water electrolysis

2025-07-28
Hybrid water electrolysis (HWE) is an emerging field that aims to overcome some of the limitations of conventional water electrolysis (CWE) for the production of green hydrogen. In CWE, two reactions take place at each of the electrodes (anode and cathode): one reaction produces hydrogen at the cathode (the hydrogen evolution reaction) and the other produces oxygen at the anode (the oxygen evolution reaction, OER). The concept of hybrid water electrolysis revolves around replacing the anode reaction of CWE (the OER), which is inefficient and requires ...

FAU researchers advise: prescribe high potency statins in treatment, prevention

2025-07-28
There is broad consensus that the overall body of evidence shows lowering LDL (low-density lipoprotein) cholesterol provides both statistically significant and clinically meaningful benefits in treating and preventing cardiovascular disease. Often referred to as the “bad” cholesterol, elevated levels of LDL can clog arteries and significantly increase the risk of heart attacks and strokes. In an invited editorial published in the current issue of Trends in Cardiovascular Medicine, researchers from Florida ...

15 regions chosen for groundbreaking effort to reduce cardiovascular disease

2025-07-28
DALLAS, July 28, 2025 — People in 15 regions across the U.S. will soon benefit from the American Heart Association’s Cardiovascular-Kidney-Metabolic Health Initiative™, designed to improve treatment of the interconnected conditions that lead to heart disease and stroke. The initiative began with five regions in February and has now expanded to include the final 10 regions. The regions include states, cities and metro areas. The initiative, supported by founding sponsors Novo Nordisk and Boehringer Ingelheim, supporting sponsor Novartis Pharmaceuticals Corporation and champion sponsor DaVita, will enroll 150 health care ...

CareQuest Institute for Oral Health to fund year six of the AADOCR Mind the Future Program

2025-07-28
Alexandria, VA – The AADOCR is now accepting applications for Cohort 6 of the Mind the Future Program, thanks to the generous support of CareQuest Institute for Oral Health.  The AADOCR Mind the Future program has been instrumental in fostering five cohorts of early-career investigators in the dental, oral, and craniofacial (DOC) research workforce. The network's principal purpose has been to establish a robust and enduring national mentoring program centrally managed by AADOCR. The overarching ...

Chungnam National University researchers reveal how vitamin D is shown to reduce liver damage by boosting TXNIP activity in cholangiocytes

2025-07-28
Chronic liver disease (CLD) is a major global health concern, affecting approximately 1.5 billion people. This life-threatening disease often progresses silently, eventually leading to worsened conditions like liver cirrhosis or liver cancer. There is currently no treatment for CLD other than liver transplantation. Vitamin D is commonly consumed for enhanced bone health. This study opens exciting possibilities for repurposing an inexpensive supplement as a complementary therapy for liver diseases. Prof. Hyo-Jung Kwon from the College of Veterinary Medicine, Chungnam National University in Daejeon, Republic of Korea, and his colleagues ...

The key to success: Why university startups don’t perform as well as corporate startups

2025-07-28
University research is where innovative technological breakthroughs originate. As a result, a number of proactive universities provide substantial resources and support to their academic researchers to help increase the number of all ventures. However, despite receiving this extensive support and having access to the best scientific knowledge, many academic entrepreneurs are not as successful as their corporate counterparts. While this sounds like a contradiction, there is enough empirical evidence explaining just why this could be happening. With this in mind, Professor Alex Coad from the Waseda Business School, Waseda University, Japan, critically analyzes the differences ...

Muscle “marbling”: Good in steak, bad in our bodies

2025-07-28
Consider the delicate web of fat in a Wagyu steak. The “marbling” that makes carnivore connoisseurs swoon is a visual heuristic for quality flavor. Now, a new study suggests the very same marbling of fat inside our own muscles points to trouble. This condition, known as intramuscular adipose tissue, or IMAT, has long been recognized by scientists as a strong indicator of poor health. It’s linked to a wide range of diseases: obesity, Type 2 diabetes, neuromuscular disorders (including Duchenne muscular dystrophy) and neurogenerative conditions such as ALS. In some cases, ...

Thousands more B.C. women chose top-tier birth control after patient costs eliminated

2025-07-28
More than 11,000 additional women opted for the most effective form of birth control—long-acting reversible contraception (LARC)—within just 15 months of B.C. making prescription contraception free. The numbers don’t lie New research from the University of British Columbia and collaborators shows a 49-per-cent jump in LARC dispensations after the province introduced universal, no-cost coverage in April 2023. That’s a seismic shift in how reproductive-aged women are managing their reproductive choice, the researchers say. The study tracked ...

Research reveals genetic weak spot in hard-to-treat cancers

2025-07-28
Australian researchers have discovered a promising new strategy to suppress the growth of aggressive and hard-to-treat cancers by targeting a specialised molecular process known as ‘minor splicing’.   Published in EMBO Reports, the study shows that blocking minor splicing can markedly slow tumour growth in liver, lung and stomach cancers, while leaving healthy cells largely unharmed.   The research in animal models and human cells, from Australian medical research institute WEHI, demonstrates ...

Coolness hits different; now scientists know why

2025-07-28
Researchers at the University of Michigan have illuminated a complete sensory pathway showing how the skin communicates the temperature of its surroundings to the brain. This discovery, believed to be the first of its kind, reveals that cool temperatures get their own pathway, indicating that evolution has created different circuits for hot and cold temperatures. This creates an elegant solution for ensuring precise thermal perception and appropriate behavioral responses to environmental changes, said Bo Duan, senior author of the new study. "The skin is the body's ...

Large-scale study defines genetic architecture of stuttering

2025-07-28
The largest genetic analysis of stuttering has demonstrated a clear genetic basis for the speech disorder, highlighting neurological pathways of risk. The study, published July 28 in the journal Nature Genetics, used data representing more than 1 million individuals who had their DNA analyzed by the company 23andMe Inc.  The findings point to 57 distinct genomic loci associated with stuttering and suggest a shared genetic architecture of stuttering with autism, depression and musicality. The results provide a foundation for additional research that could lead to earlier identification or therapeutic advances in stuttering. More broadly, improving understanding of the causes ...

Decoding the blue: Advanced Technology realizes potential in harmful algal bloom monitoring

2025-07-28
Researchers at the University of Birmingham have developed a powerful new method to detect harmful blue-green algae in freshwater lakes. Their method, which involves advanced mass spectrometry technology, can identify toxin producing blue-green algae before they become damaging in recreational waters and pose threat to public health. Blue-green algae (scientifically named as cyanobacteria) are micro-organisms commonly found in ponds, lakes, and oceans worldwide. In optimum growth conditions, they can form huge “blooms” that appear like green slime covering the surface of the water. Although these blooms are extremely ...

How plants are learning to spot sneaky bacterial invaders

2025-07-28
Scientists at the University of California, Davis, used artificial intelligence to help plants recognize a wider range of bacterial threats — which may lead to new ways to protect crops like tomatoes and potatoes from devastating diseases. The study was published in Nature Plants.  Plants, like animals, have immune systems. Part of their defense toolkit includes immune receptors, which give them the ability to detect bacteria and defend against it. One of those receptors, called FLS2, helps plants recognize flagellin — a protein in the tiny tails bacteria use to swim. But bacteria are sneaky and constantly ...

One in 11 older Canadians has experienced depression, University of Toronto study finds

2025-07-28
Toronto, Canada – A new study of 3,500 Canadians aged 55 and older revealed a strong association between early childhood adversities and depression. Experiencing physical abuse in childhood was linked to a threefold increase in the likelihood of lifetime depression, while exposure to sexual abuse or parental domestic violence more than doubled the risk. The University of Toronto research was published recently in Archives of Gerontology and Geriatrics Plus. “Our findings shine a light on how trauma in the earliest years can echo through decades, shaping patterns of mental health and well-being,” says the first author, Megha Goel, a doctoral student at the University ...

VR nature scenes reduce sensitivity to pain – especially for those who feel present during the experience

2025-07-28
Immersing in virtual reality (VR) nature scenes helped relieve symptoms that are often seen in people living with long-term pain, with those who felt more present experiencing the strongest effects. A new study led by the University of Exeter, published in the journal Pain, tested the impact of immersive 360-degree nature films delivered using VR compared with 2D video images in reducing experience of pain, finding VR almost twice as effective.   Long-term (chronic) pain typically lasts more than three months and is particularly difficult to treat. The researchers simulated this type of pain in healthy participants, ...
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