Healing a broken bone can take months, and knowing whether recovery is on track often takes just as long. Doctors typically rely on periodic X-rays, capturing two-dimensional images to see how the bone is growing back together. Patients return for follow-up scans every few weeks or months, repeating the cycle until the bone shows signs of complete healing. Healing of shin bone (tibia) fractures, in particular, slows or stalls up to 25% of the time. Factors such as age or underlying health conditions like diabetes can influence the speed of fracture healing. Delayed or incomplete ...

As breast cancer survival rates continue to climb — 4.3 million women in the U.S. are currently living with a history of the disease and in the next 10 years that number is expected to rise by another million — heart health has become an increasingly important part of survivorship care.  Certain breast cancer therapies, while lifesaving, can also place stress on the heart, raising important questions about who might benefit from closer monitoring. But does every breast cancer survivor need ...

Moffitt Cancer Center researchers report the first clinical activity of a RAS inhibitor in patients with NRAS-mutant melanoma.  The investigational drug daraxonrasib (RMC-6236) and its preclinical counterpart RMC-7977 bind active RAS proteins (NRAS, HRAS, KRAS) and block downstream signaling that drives tumor growth, survival and immune escape.  In laboratory models, treatment led to increased infiltration of activated T cells, reduction of suppressive immune cells and tumor eradication only when the immune ...

UNIVERSITY PARK, Pa. — It doesn’t take technical expertise to work around the built-in guardrails of artificial intelligence (AI) chatbots like ChatGPT and Gemini, which are intended to ensure that the chatbots operate within a set of legal and ethical boundaries and do not discriminate against people of a certain age, race or gender. A single, intuitive question can trigger the same biased response from an AI model as advanced technical inquiries, according to a team led by researchers at Penn State.  “A lot of research on AI bias has relied on sophisticated ...

For the first time, a research team led by the Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of Medicine of USC has mapped the genetic architecture of a crucial part of the human brain known as the corpus callosum—the thick band of nerve fibers that connects the brain’s left and right hemispheres. The findings open new pathways for discoveries about mental illness, neurological disorders and other diseases related to defects in this part of the brain. The corpus callosum is critical for nearly everything the brain does, from coordinating ...

Rice University is partnering with researchers at the University of Washington, Columbia University and Louisiana State University on a $2 million award from the National Science Foundation to revolutionize how materials and microrobots can be designed, controlled and applied in real-world environments. Funded through NSF’s Designing Materials to Revolutionize and Engineer our Future (DMREF) program, the four-year project — Adaptive and Responsive Magnetic Swarms (ARMS) — aims to create microscopic robotic swarms that move and think collectively, much like schools of fish or flocks of birds. Led by principal investigator Zach ...

EAST LANSING, Mich. – Can an AI persona detect when a human is lying – and should we trust it if it can? Artificial intelligence, or AI, has had many recent advances and continues t  evolve in scope and capability. A new Michigan State University–led study is diving deeper into how well AI can understand humans by using it to detect human deception.  In the study, published in the Journal of Communication, researchers from MSU and the University of Oklahoma conducted 12 experiments with over 19,000 AI participants to examine how well AI personas were ...

In the development of Parkinson’s disease, it may not be a good idea to turn the amp to 11. High-volume noise exposure produced motor deficits in a mouse model of early-stage Parkinson’s disease, and established a link between the auditory processing and movement areas of the brain, according to a study published November 4th in the open-access journal PLOS Biology by Pei Zhang from the Huazhong University of Science and Technology in Wuhan, China, and colleagues. The environment can play an important role in the development of Parkinson’s disease, but how sound volume in particular might impact the severity of symptoms was unknown. To understand how ...

The rates of bloodstream infections caused by drug-resistant bacteria will increase substantially across Europe in the next five years, driven largely by aging populations, according to a new paper published November 4th in the open-access journal PLOS Medicine by Gwenan Knight of the London School of Hygiene and Tropical Medicine, UK, and colleagues. Antimicrobial resistance (AMR) is a global public health crisis. To effectively target interventions and track progress toward international goals, accurately estimating how the AMR burden will change over time is necessary. In ...

New research has updated our understanding of how sugars, known as glycans, help immune cells move into skin in the inflammatory disease, psoriasis. The paper entitled “Leukocytes have a heparan sulfate glycocalyx that regulates recruitment during psoriasis-like skin inflammation” published in the journal Science Signaling. The lead authors are Dr Amy Saunders from Lancaster University  and Dr Douglas Dyer from the University of Manchester, with their joint PhD student, ...

Peking University, November 4, 2025: A research team led by Professor Zhang Qinghong and Li Rumeng from the Department of Atmospheric and Oceanic Sciences at Peking University (PKU) School of Physics, has found that hailstorms in China have surged since the Industrial Revolution, likely due to human-driven climate warming. The study, published in Nature Communications in September 2025, combines historical records, meteorological data, and artificial intelligence to track long-term hailstorm trends. Why It Matters: Hail can fall fast and hit hard. Apart from smashing crops and damaging homes, it may even endanger lives. After 2024’s record-breaking ...

A neural computation first discovered in insects has been shown to explain how humans combine sight and sound – even when illusions trick us into “hearing” what we do not see. Now, researcher Dr Cesare Parise from the University of Liverpool, UK, has created a biologically grounded model based on this computation, which can take in real-life audiovisual information instead of more abstract parameters used in previous models. Parise’s research, published today in eLife as the final Version of ...

WASHINGTON, Nov. 4, 2025 — LEDs, or light-emitting diodes, are essential components in near-eye displays like virtual reality and augmented reality headsets and smart glasses, along with electronics like cameras and medical equipment. Conventional LEDs use direct current power, which requires two contacts, like the positive and negative contacts to connect a battery. As device form factors continue to shrink, fabricating nano-LEDs requires each of the hundreds of microscopic components to touch both contacts, which presents a complicated alignment problem for device manufacturers. In Applied Physics Letters, ...

About The Study: The findings of this modeling study suggest that achieving systolic blood pressure equity between non-Hispanic Black and white adults could substantially reduce the number of cardiovascular disease events and deaths experienced by non-Hispanic Black U.S. adults. Initiatives to maintain normal blood pressure and achieve blood pressure control for individuals with hypertension could have a substantial impact on health equity in the U.S.  Corresponding Author: To contact the corresponding author, Shakia T. ...

About The Study: The findings of this cohort study suggest that facility-based colorectal cancer screening among adults ages 45 to 49 increased nearly 10-fold following U.S. Preventive Services Task Force (USPSTF) guideline changes, far exceeding growth among those ages 50 to 75. This rapid adoption highlights early implementation by practitioners and patients. Although screening rates among adults ages 50 to 75 increased during the study period, the accelerated growth among those ages 45 to 49 reflected guideline ...

A hidden structure inside the cell is rewriting how scientists understand leukemia. Beneath the microscope, what looked like disorder turned out to follow a simple physical rule – one that connects several major mutations behind the disease.   In new research from Baylor College of Medicine published in Cell, scientists reveal that different genetic drivers of leukemia use the same secret compartments inside the cell nucleus to keep cancer growing. The finding points to a shared physical target that could inspire new kinds of treatments.   The ...

CAMBRIDGE, MA - MIT engineers have developed a flexible drug-delivery patch that can be placed on the heart after a heart attack to help promote healing and regeneration of cardiac tissue. The new patch is designed to carry several different drugs that can be released at different times, on a pre-programmed schedule. In a study of rats, the researchers showed that this treatment reduced the amount of damaged heart tissue by 50 percent and significantly improved cardiac function. If approved for use in humans, ...

A new study by investigators from Mass General Brigham shows that patients with traumatic spinal cord injuries (TSCI) are at a higher risk of developing a myriad of chronic health problems, regardless of age, location of the injury and prior health status. Their results are published in JAMA Network Open. “The journey doesn't end when patients with traumatic spinal cord injuries leave the hospital or rehab,” said corresponding author Saef Izzy, MD, FAAN, FNCS, a neurologist in the Department of Neurology at Mass General Brigham. “Programs should be implemented to identify patients at risk so that ...

Temperature is a key physiological factor that determines the speed of immune reactions. While this may seem obvious, it has remained largely unexplored at the single-cell level—until now. Stefan Wieser from the Institute of Zoology at the University of Innsbruck and his colleagues report in Developmental Cell that the motor protein Myosin II regulates the temperature sensitivity of immune cells and drives the acceleration of immune responses at elevated body temperature. Wieser first noticed that temperature affects the movement of immune ...

Contrails form when hot exhaust gas from an aircraft’s engine mixes with the cold air at an altitude of about 10 kilometres. In dry air, most contrails dissipate quickly. In cold, humid air, however, they can persist for several hours and develop into extensive cirrus clouds. Cirrus clouds are high, thin ice clouds at an altitude of about 5 to 12 kilometres, which often appear as delicate, wispy veils in the sky. Until now, researchers had assumed that long-lived contrails form mainly in clear skies, where they exert their warming effect. However, the new study shows that they mostly form within existing natural ...

ukuoka, Japan—Researchers at Kyushu University have designed a class of molecules whose ability to amplify light energy can be actively controlled by simply applying pressure. The findings, published in the journal Chemical Science, may open new possibilities for highly efficient energy conversion devices and advanced medical therapies. The study is centered on a physical process called singlet fission (SF). SF is a mechanism where, when a molecule is struck by a single high-energy photon, it splits that energy to create two lower-energy excited states instead of just one. In effect, it acts like an ...

Bullying and lack of psychological support from managers top the list of workplace factors that can lead to serious mental health problems, according to a new investigation of work-related anxiety in four countries. The study shows that 11.2 per cent of people in Norway have reduced capacity for work due to work-related anxiety. “Work-related anxiety is not just stress. Anxiety is the worry that follows you home, steals your sleep, and meets you again the next day at work,” said Leon De Beer, an associate professor at the Norwegian ...

November 4, 2025 – The American Pediatric Society (APS) is pleased to announce Harolyn Belcher, MD, MHS, as the 2026 David G. Nichols Health Equity Award recipient. The David G. Nichols Health Equity Award, administered by the APS and endowed by the American Board of Pediatrics (ABP) Foundation, was created to recognize demonstrated excellence in advancing child and adolescent health, well-being, and equity through quality improvement, advocacy, practice, or research. This award recognizes Dr. Belcher’s ...

PASADENA, CA — November 4, 2025 — The GMTO Corporation, the 501(c)(3) nonprofit and international consortium building the Giant Magellan Telescope, today announced a leadership transition on its Board of Directors. After nearly a decade of leadership as chair, Dr. Walter Massey is retiring. The board has elected Dr. Taft Armandroff as its new chair and Nobel Laureate Dr. Brian Schmidt as vice chair. Dr. Massey’s tenure guided the Giant Magellan Telescope through key design and construction milestones, helped secure nearly $500 million in private and ...

The College of Engineering and Computer Science at Florida Atlantic University has received a $1.5 million gift from the Aaron Family Foundation and Ubicquia, Inc., a Fort Lauderdale-based technology company, to establish the “Ubicquia Innovation Center for Intelligent Infrastructure” (UICII). Ubicquia is a global leader in artificial intelligence-driven sensors and software platforms that help utilities and municipalities improve grid resiliency, reduce energy consumption, and enhance public safety. The UICII will serve as an accelerator for innovation, design and deployment of leading-edge industrial sensors, ...