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Clinical trials reveal promising alternatives to high-toxicity tuberculosis drug

2025-07-08
The drugs, sutezolid and delpazolid, have demonstrated strong antimicrobial activity and a notably better safety profile compared to linezolid, with potential to replace this current cornerstone in the treatment of drug-resistant TB. The findings were published on 7 July in two peer-reviewed articles in The Lancet Infectious Diseases, one of the world’s leading journals in the field of infectious disease medicine. Research partners in Europe included Radboud university medical center from the Netherlands and the German Center for Infection Research (DZIF), Munich, the Fraunhofer Institute for Translational Medicine and Pharmacology ...

Artificial solar eclipses in space could shed light on Sun

2025-07-08
Recreating artificial solar eclipses in space could help astronomers decipher the inner workings of our Sun much quicker than if they had to wait for the celestial show on Earth. The plan, part of a UK-led space mission to be unveiled at the Royal Astronomical Society’s National Astronomy Meeting 2025 in Durham, would involve the use of a mini-satellite and the Moon's shadow to achieve the closest-ever views of the Sun's atmosphere. The Moon-Enabled Sun Occultation Mission (MESOM) proposes a novel way to study the inner solar corona – the innermost layer of the Sun's atmosphere, which ...

Probing the cosmic Dark Ages from the far side of the Moon

2025-07-08
Royal Astronomical Society press release RAS PR 25/26 (NAM 6) 8 July 2025 Embargoed until Wednesday 9 July 2025 at 00:01 BST Astronomers want to unlock the secrets of the 'Cosmic Dawn' by sending a miniature spacecraft to listen out for an "ancient whisper" on the far side of the Moon. The proposed mission will study the very early universe, right after the Big Bang, when it was still quite dark and empty before the first stars and galaxies appeared. But to probe the cosmic 'Dark ...

UK hopes to bolster space weather forecasts with Europe's first solar storm monitor

2025-07-08
Royal Astronomical Society press release RAS PR 25/27 (NAM 7) 8 July 2025 Embargoed until Wednesday 9 July 2025 at 00:01 BST A new UK-led satellite mission concept aims to strengthen the country's position in space weather observation and forecasting by deploying a suite of homegrown scientific instruments on a low-cost spacecraft in low-Earth orbit. The proposal is being presented today (Wednesday) at the Royal Astronomical Society's National Astronomy Meeting 2025 in Durham. UK-ODESSI ...

Can one video change a teen's mindset? New study says yes - but there’s a catch

2025-07-08
A mental health hack designed to promote mental well-being could shift how teenagers view themselves – according to new research from the University of East Anglia. A new study published today shows how watching a one-off ten-minute video can positively change young people’s beliefs about their personality traits. But the intervention appeared to have little immediate effect on symptoms of anxiety or depression. The findings add to a growing body of evidence that mental health support delivered online can play a valuable role - but may work best as part of a broader toolkit of services. The team say that more ...

How lakes connect to groundwater critical for resilience to climate change, research finds

2025-07-08
Understanding whether lakes are fed predominantly by groundwater or rainwater is critical to managing our water resources in the face of droughts and shortages, new research has found. The study drew on data from 350 lakes across 18 European countries, collected between 2022 and 2024, to provide a comprehensive picture of how the continent’s lakes are coping with climate change. The research is presented today [Wednesday 9 July, 2025] at the Goldschmidt Conference in Prague. The researchers, from the Czech Academy of Sciences, analysed the proportions of stable hydrogen and oxygen isotopes (18O and 2H) in the lakes’ ...

Youngest basaltic lunar meteorite fills nearly one billion-year gap in Moon’s volcanic history

2025-07-08
A 2.35-billion-year-old meteorite with a unique chemical signature, found in Africa in 2023, plugs a major gap in our understanding of the Moon’s volcanic history.   Presented today [Wednesday 9 July] at the Goldschmidt Conference in Prague, findings from analyses of the Northwest Africa 16286 meteorite offer fresh insights into how the Moon’s interior evolved, highlighting the long-lived nature of its volcanic activity. Analyses by researchers from the University of Manchester, UK, lend weight to a theory that the Moon retained internal heat-generating processes that powered ...

Cal Poly Chemistry professor among three U.S. faculty to be honored for contributions to chemistry instruction

2025-07-08
A Cal Poly chemistry professor is among three U.S. university faculty to be awarded the national Jack Flack Norris Award for outstanding teaching in chemistry by the American Chemical Society. Dr. Phil Costanzo is being recognized for his work with the Macromolecular Alliance for Community Resources & Outreach (MACRO), a joint service committee of two American Chemical Society divisions: Polymer Chemistry (POLY) and Polymeric Materials: Science & Engineering (PMSE).  The award celebrates MACRO’s outstanding achievements in chemistry education and its extensive, ...

Stoichiometric crystal shows promise in quantum memory

2025-07-08
For over two decades, physicists have been working toward implementing quantum light storage—also known as quantum memory—in various matter systems. These techniques allow for the controlled and reversible mapping of light particles called photons onto long-lived states of matter. But storing light for long periods without compromising its retrieval efficiency is a difficult task. In recent years, rare earth atoms in solid materials at cryogenic temperatures have shown to be promising for quantum memory. ...

Study sheds light on why some prostate tumors are resistant to treatment

2025-07-08
ANN ARBOR, Michigan — A new study from University of Michigan Rogel Cancer Center researchers identifies a cellular signature that explains why about one-third of prostate cancers respond especially poorly to treatment.   Treatments such as enzalutamide, which is an androgen receptor pathway inhibitor (ARPI), are standard of care for advanced prostate cancer. While many patients have long-term good response to the drugs, some will derive no benefit whatsoever. These “extreme non-responder” patients die much more quickly ...

Tree pollen reveals 150,000 years of monsoon history—and a warning for Australia’s northern rainfall

2025-07-08
Northern Australia's annual monsoon season brings relief to drought-stricken lands and revitalises crops and livestock for farmers. But a study of 150,000 years of climate records shows that the monsoon is likely to intensify — triggering a higher risk of flooding while worsening the impact of droughts in East Asia. Led by Professor Michael Bird, researchers at James Cook University and Flinders University have assessed sediments at Girraween Lagoon near Darwin, revealing a continuous record of monsoon rainfall patterns dating back beyond the last interglacial period. This ...

Best skin care ingredients revealed in thorough, national review

2025-07-08
Retinoids and mineral sunscreen among the most effective for multiple skin complaints Full list of recommended ingredients for each skin concern included in study Nearly 80 dermatologists from 43 institutions participated in a robust national ingredient review CHICAGO --- From drugstore aisles to TikTok trends, consumers are bombarded with skin care products. But how do you know what really works, especially now with summer in full swing? A Northwestern Medicine study offers clarity, identifying the ingredients that dermatologists agree are most effective ...

MicroRNA is awarded an Impact Factor Ranking for 2024

2025-07-08
Bentham Science Publishers is pleased to announce that MicroRNA has been awarded an Impact Factor ranking by Clarivate Analytics. The journal, currently edited by Dr. Alberto Izzoti (University of Genoa), has been providing readers with cutting-edge research on molecular biology and the therapeutic applications of MicroRNAs. Bentham Science extends its heartfelt congratulations to all journal contributors, including editors, authors and staff who have supported the journal since its inception. Impact Factor Update: With MicroRNA’s addition to the Impact Factor list, ...

From COVID to cancer, new at-home test spots disease with startling accuracy

2025-07-08
Got a sore throat and the sniffles? The recent rise of rapid at-home tests has made it easier to find out if you have a serious illness like COVID-19 or just a touch of spring allergies.  But while quick and convenient, these at-home tests are less sensitive than those available at the doctor’s office, meaning that you may still test negative even if you are infected. A solution may come in the form of a new, low-cost biosensing technology that could make rapid at-home tests up to 100 times more sensitive to ...

Now accepting submissions: Special Collection on Cognitive Aging

2025-07-08
In this special collection, Aging seeks to bring together cutting-edge research that spans the cellular and molecular underpinnings of cognitive aging with insights into the psychosocial, behavioral, and environmental factors that modulate its course. BUFFALO, NY — July 8, 2025 — As populations worldwide continue to age, understanding the mechanisms and manifestations of cognitive aging is increasingly urgent for science, medicine, and society. Age-related cognitive decline ranges from mild memory lapses to the onset of dementia, and is shaped by a complex interplay of molecular, cellular, systemic, and social ...

Young adult literature is not as young as it used to be

2025-07-08
OXFORD, Miss. – Despite its name, the young adult genre is increasingly dominated by stories about older teens and even adults. But as protagonists get older, younger readers are getting left behind, a University of Mississippi study indicates.   Ally Watkins, research and instruction librarian at the J.D. Williams Library, published her research into the increasing age of young adult protagonists in the New Review of Children's Literature and Librarianship.   “I think it's important for any reader to see themselves ...

Can ChatGPT actually “see” red? New results of Google-funded study are nuanced

2025-07-08
ChatGPT works by analyzing vast amounts of text, identifying patterns and synthesizing them to generate responses to users’ prompts. Color metaphors like “feeling blue” and “seeing red” are commonplace throughout the English language, and therefore comprise part of the dataset on which ChatGPT is trained. But while ChatGPT has “read” billions of words about what it might mean to feel blue or see red, it has never actually seen a blue sky or a red apple in the ways that humans have. Which begs the questions: Do embodied experiences — the capacity ...

Turning quantum bottlenecks into breakthroughs

2025-07-08
Quantum computers have operated under a significant limitation: they can run only one program at a time. These million-dollar machines demand exclusive use even for the smallest tasks, leaving much of their expensive and fast-running hardware idle and forcing researchers to endure long queues. Columbia Engineering researchers have developed HyperQ, a novel system that enables multiple users to share a single quantum computer simultaneously through isolated quantum virtual machines (qVMs). This key development brings quantum computing closer to real-world usability—more practical, ...

Cancer-fighting herpes virus shown to be an effective treatment for some advanced melanoma

2025-07-08
LOS ANGELES — The herpes simplex virus type 1 (HSV-1), which affects almost two-thirds of the world’s population and is generally associated with oral herpes, may cause painful cold sores or fever blisters around the mouth.    Yet, when genetically engineered to fight cancer, the virus may also play an important role in treating advanced melanoma, skin cancer that has spread to other parts of the body, according to phase 1-2 clinical trial results published in the Journal of Clinical ...

Eliminating invasive rats may restore the flow of nutrients across food chain networks in Seychelles

2025-07-08
Ecosystems are characterized by interconnected structure and functions. A study published July 8th in the open-access journal PLOS Biology by Casey Benkwitt at Lancaster University, United Kingdom and colleagues suggests that restoring seabird populations via eradication of rats may help coral reefs by restoring nutrient connectivity in disrupted food chains. Invasive rats in the Seychelles have decreased native seabird populations. However, the mechanism by which seabirds may impact coral reef ecosystem structure ...

World’s first: Lithuanian scientists’ discovery may transform OLED technology and explosives detection

2025-07-08
In modern devices, such as phone screens or advanced sensors, light is often generated by pairs of organic molecules, where one molecule, known as the donor, transmits electrons, and the other, referred to as the acceptor, receives them. An international team of scientists from Kaunas University of Technology, KTU, Lithuania, has, for the first time, observed the luminescence of an excited complex formed by two donor molecules. This discovery opens new possibilities for developing simpler, more efficient, and more sustainable optoelectronic devices. “Until now, such interactions were considered practically impossible. This discovery challenges the fundamental principles we have used ...

Rice researchers develop superstrong, eco-friendly materials from bacteria

2025-07-08
HOUSTON – (July 8, 2025) – Scientists at Rice University and University of Houston have developed an innovative, scalable approach to engineer bacterial cellulose into high-strength, multifunctional materials. The study, published in Nature Communications, introduces a dynamic biosynthesis technique that aligns bacterial cellulose fibers in real-time, resulting in robust biopolymer sheets with exceptional mechanical properties. Plastic pollution persists because traditional synthetic polymers degrade into microplastics, releasing harmful chemicals like bisphenol ...

Itani studying translation potential of secure & efficient software updates in industrial internet of things architectures

2025-07-08
Itani Studying Translation Potential Of Secure & Efficient Software Updates In Industrial Internet of Things Architectures Wassim Itani, Associate Professor, Computer Science, College of Engineering and Computing (CEC), received funding for the project: “I-Corps: Translation Potential of Secure and Efficient Software Updates in Industrial Internet of Things Architectures (IIoT).” He is addressing several critical challenges, including limited computing and network resources of IIoT devices, lack of operational and security standards, absence of a cryptographic root of trust, unique operational requirements of IIoT ...

Elucidating the source process of the 2021 south sandwich islands tsunami earthquake

2025-07-08
Tsukuba, Japan—Tsunami earthquakes are characterized by the generation of disproportionately large tsunamis relative to the observed ground shaking, complicating timely evacuation efforts. Understanding their generation mechanisms and associated risks is therefore critical. One proposed cause is slow, uniform fault slip facilitated by soft sedimentary layers in the source region; however, this mechanism remains poorly understood. Additionally, the seismic signals from tsunami earthquakes are often too complex to be explained by conventional models, and their source processes have not been fully clarified. In this study, the research team analyzed seismic waveform data from ...

Zhu studying use of big data in verification of route choice models

2025-07-08
Zhu Studying Use Of Big Data In Verification Of Route Choice Models Shanjiang Zhu, Associate Professor, Civil, Environmental, and Infrastructure Engineering, College of Engineering and Computing (CEC), received funding for the study: “Utilizing Big Data to Verify and Enhance Route Choice Models in Travel Demand Modeling.” Connected vehicle data has attracted a lot of interest from transportation professionals, but researchers are still exploring the best way to use it. This research effort will determine the best way to use connected vehicle data to enhance accuracy of travel demand models. It will challenge the conventional ...
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