A new IgG ELISA assay for mpox antibodies was developed and validated at Rwanda's National Reference Laboratory during the clade 1b outbreak, using just four key antibody signatures to keep the test affordable and accessible in remote settings.

Structural changes in three blood proteins, C1QA, clusterin, and apolipoprotein B, distinguished cognitively normal adults from Alzheimer's patients with up to 93% accuracy in two-way comparisons, suggesting protein folding may offer a new diagnostic window.

By adding a Nafion ionomer to cobalt phthalocyanine electrodes, researchers achieved 93% CO Faradaic efficiency at 300 mA/cm2 in bicarbonate electrolysis, demonstrating a closed-loop CO2 capture-and-conversion cycle from simulated flue gas.

Analysis of hundreds of ethnographic documents shows bone needles and awls were most commonly used for clothing production, with mentions increasing significantly in colder environments, but these tools also served medical, ceremonial, and artistic purposes across North America.

Researchers identified SYFO2 as the molecular gatekeeper that reorganizes the actin cytoskeleton in legume root hairs, enabling nitrogen-fixing rhizobia to enter. The protein was also activated in tomato, suggesting a path to engineering self-fertilization in non-legume crops.

A new machine-learning tool trained on data from just four published papers can predict which mirror-image version of a molecule a chemical reaction will produce, potentially cutting drug-synthesis screening from 50-60 experiments down to 5-10.

Soaking pruned litchi branches in limewater before open burning boosts carbon retention from 52% to 86%, creating stable biochar that could sequester roughly 6,000 kg of carbon per hectare without requiring industrial equipment.

Two companion position papers from the American College of Physicians, published in Annals of Internal Medicine, lay out policy recommendations for making healthcare accessible to patients with disabilities and the medical profession inclusive of physicians and trainees with disabilities.

A study in Materials Today Chemistry provides the first detailed structural comparison of two moisture-swing direct air capture materials, finding that the polymer with larger pores captures more CO2 and does so faster, offering design principles for next-generation carbon removal systems.

A study in Stem Cell Reports reveals that the enzyme Setd8 preserves open chromatin in retinal progenitor cells, maintaining their capacity to produce new neurons during eye development. Without it, cells show reduced proliferation, increased DNA damage, and thinner retinas.

A Drexel and University of Washington study analyzing all 203 American Indian/Alaska Native people killed by police from 2013-2024 finds 73% of deaths occurred on or within 10 miles of reservations, despite only 40% of AIAN people living there, with disproportionate risk persisting after controlling for population density.

A UC San Diego study of 267 genomes from autism families demonstrates that long-read whole genome sequencing enhances discovery of gene-disrupting structural variants and tandem repeats by 33% and 38% respectively compared to traditional methods, addressing part of autism's missing heritability.

A study of over 4,500 Baltic Sea herring from 150 spawning locations reveals genetically distinct populations adapted to local salinity and temperature, including clusters and subgroups that do not correspond to current fishery management boundaries.

Rutgers researchers demonstrate in a microfluidic experiment that bacteria living inside marine snow particles create acidic microenvironments that dissolve calcium carbonate, potentially weakening the ocean's ability to sequester carbon and complicating future climate projections.

A PNAS study reveals that bacteria on sinking marine snow particles dissolve calcium carbonate ballast through acidic waste products, potentially reducing how deep and fast carbon sinks into the ocean and weakening a critical natural carbon sequestration mechanism.

An international team of 16 physicists argues in a PNAS perspective that room-temperature superconductivity has no fundamental physical barrier, proposes a systematic research agenda combining AI with experiment, and points to a new pressure-quenching record of 151 Kelvin as proof of recent momentum.

Washington University researchers have built a state-level vulnerability index for influenza-like illness using machine learning and 39 census-derived indicators, revealing that population density, uninsured populations, aging demographics, and poverty create distinct risk profiles across states.

A Children's National Hospital study using fMRI shows that newborns with congenital heart disease have atypical brain networks for sensory perception, movement, and social behavior before cardiac surgery, with networks improving toward healthy patterns after the procedure.

A study of 30 listeners found people are poor at consciously distinguishing AI-generated from human speech, but training produced measurable changes in brain activity that differentiated the two, suggesting the auditory system detects cues that conscious judgment has not yet learned to use.

Engineers at the University of Pennsylvania have built LIBRIS, an automated microfluidic platform that formulates lipid nanoparticles 100 times faster than manual methods, generating the large datasets needed to train AI models for rational mRNA delivery design.

In a randomized trial of 958 older adults, two years of daily multivitamin use slowed biological aging by approximately four months as measured by five epigenetic clocks, with statistically significant effects on the two clocks most predictive of mortality.

A Duke University study in Immunity reveals that resident macrophages living in the eye's drainage tissue actively prevent clogs that lead to elevated pressure and glaucoma, offering the first immune-based target for treating the leading cause of irreversible blindness.

After the Organ Procurement and Transplantation Network required wait time corrections for Black kidney transplant candidates disadvantaged by race-based equations, over 21,000 candidates gained an average 1.7 years of priority, and Black transplant rates rose by 5.3 per 1,000 listings.

A UNC Chapel Hill study using objective smartphone tracking found students spend one-third of the school day on their phones, checking them every hour, with social media and entertainment accounting for over 70% of usage and frequent checking linked to poorer cognitive control.

Scientists at the University of Illinois have built the first simulation of a complete bacterial cell cycle, tracking every molecular interaction in a minimal cell from DNA replication through division, with results matching real-world timing within two minutes.