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Researchers develop novel treatment for central nervous system injury

2025-08-28
Traumatic injuries of the central nervous system (CNS)—such as traumatic brain injury (TBI) and traumatic spinal cord injury (SCI)—are characterized by oxidative damage and neuroinflammation. Current treatment relies mainly on supportive care and surgical intervention, with a lack of effective drugs to directly target the underlying damage. For example, neural stem cell (NSC)-based therapy has shown therapeutic potential, but pathological microenvironments negatively impact NSC survival and directed differentiation, compromising therapeutic outcomes. Similarly, antioxidant treatment ...

Debt, bankruptcy, and credit scores after cancer diagnosis

2025-08-28
About The Study: In this retrospective cohort study, modest amounts of medical debt in collections persisted for years after cancer diagnosis. Total debt in collections was present at higher amounts for certain cancer subpopulations. The persistence of adverse financial outcomes after cancer diagnosis, despite high rates of insurance coverage in Massachusetts, warrants further research and consideration of broader systemic reforms. Corresponding Author: To contact the corresponding author, Benjamin C. James, MD, MS, email bjames1@bidmc.harvard.edu. To ...

Glucagon-like peptide-1 receptor agonists and risk of uveitis

2025-08-28
About The Study: This cohort study found that glucagon-like peptide-1 receptor agonist (GLP-1RA) prescriptions were associated with a lower risk of uveitis compared with controls. These findings suggest potential anti-inflammatory benefits beyond glycemic control, warranting further investigation into their role in ocular inflammatory diseases. Corresponding Author: To contact the corresponding author, Sumit Sharma, MD, email sumitsharma.md@gmail.com. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamaophthalmol.2025.2822) Editor’s Note: Please see the article for additional ...

Study proposes new, more personalized methadone restart approach for opioid use disorder

2025-08-28
AURORA, Colo. (August 28, 2025) – A new study from University of Colorado Anschutz and Denver Health researchers, published today in JAMA Network Open, introduces a more individualized approach to restarting methadone treatment for people with opioid use disorder. The findings suggest that tailoring methadone doses to each patient’s unique circumstances can improve care without compromising safety. Methadone is a proven medication that can cut the risk of death from opioid use disorder by about 50%. The researchers considered that current treatment protocols ...

Majority of oncology staff at Moroccan Cancer Institute affected by burnout

2025-08-28
“Burnout is highly prevalent among oncology healthcare professionals in Morocco, particularly among young female nurses.” BUFFALO, NY — August 28, 2025 — A new research paper was published in Volume 12 of Oncoscience on July 31, 2025, titled “Burnout among oncology nurses and technicians in Morocco: Prevalence, risk factors, and structural equation modeling.” In this study, Imane Errami, Saber Boutayeb, and Hassan Errihani from the Faculty of Medicine and Pharmacy at University Mohammed V of Rabat investigated ...

People who skip breakfast and eat late dinners may have a higher risk of osteoporosis

2025-08-28
WASHINGTON—People who skip breakfast and eat late dinners may have an increased risk of developing osteoporosis, according to a new study published in the Journal of the Endocrine Society. Lifestyle habits, such as exercise, alcohol consumption and smoking, are known to increase people’s risk of osteoporosis, however little is known about the association between osteoporotic fracture and diet. “This study aimed to examine the association between lifestyle habits such as diet, and the risk of osteoporotic fracture,” ...

Pertussis resurgence in Tuscany outlines importance of timely vaccination in Italy

2025-08-28
Pertussis, commonly known as whooping cough, is a vaccine-preventable disease which continues to circulate even in areas where vaccination coverage is high, and outbreaks may still occur. A study published in Eurosurveillance and conducted at Meyer Children’s Hospital in Florence, Italy, has found a sharp increase in hospitalisations for pertussis among children and adolescents (patients aged 16 years or under) in 2024. The findings highlight the critical role of not only adhering to vaccination schedules but also administering doses at the earliest opportunity to ensure a further reduction in cases and hospitalisations ...

Innovative food processing technologies: a path to nutritional efficiency in staple crops

2025-08-28
In a world where the demand for healthier diets is on the rise, a new review published in Engineering explores how innovative food processing technologies can enhance the utilization of nutrients in staple food crops. The study, titled "Innovative Food Processing Technologies Promoting Efficient Utilization of Nutrients in Staple Food Crops," delves into the challenges of traditional food processing methods and highlights the potential of modern techniques to improve nutritional profiles ...

We must develop thinkers, not crammers and fact experts

2025-08-28
Hilde Storrøsæter is worried about the teaching of geography in schools. Geography as a school subject is under pressure. There aren't enough qualified teachers and it loses out to other subjects in school. In many countries, important aspects are left out of the geography curricula.  "Alarm bells should be ringing, both in the field and among teachers in schools. The development we are seeing in geography as a subject is critical. This failure affects the students' ability to understand how things are connected in a troubled and confusing world," she said. Storrøsæter is a geographer and assistant professor at the Norwegian University ...

Political polar opposites may be more alike than they think

2025-08-28
The brains of politically extreme individuals, whether left- or right-leaning, appear to respond to and process political information in surprisingly similar ways, according to research published by the American Psychological Association. “Both extreme liberals and extreme conservatives consumed the same political content, and even though they held vastly different beliefs, their brains appeared to process the information in a very similar manner,” said Oriel FeldmanHall, PhD, a professor of cognitive and psychological sciences at Brown University and co-author of the study, published in the Journal of Personality and Social Psychology. “In contrast, ...

GI tumor microbes may predict prognosis and inform treatment

2025-08-28
Key Points: Gastrointestinal cancers account for half of new cancer diagnoses worldwide. Intratumor microbes can play a role in disease progression and response to treatment. Researchers have identified core tumor microbiota associated with disease progression and risk. A microbiota-based risk score can predict response to therapy and complement existing tools. Washington, D.C.—Microbes inside cancerous tumors can influence the spread of disease and the effectiveness of treatment. Those roles make them appealing targets for new therapies and offer ways to better predict risk. Tumor ...

Study linking depression to specific altered brain cells opens door to new treatments

2025-08-28
Researchers at McGill University and the Douglas Institute have identified two specific types of brain cells that are altered in people with depression. The study, published in Nature Genetics, opens the door to developing new treatments that target these cells and deepens our understanding of depression, a leading cause of disability worldwide that affects more than 264 million people. “This is the first time we’ve been able to identify what specific brain cell types are affected in depression by mapping gene activity together ...

How plants rot: New method decodes hidden decomposers of wood and leaves

2025-08-28
FRANKFURT. When a tree dies, it forms the foundation for new life: In a slow, invisible process, leaves, wood and roots are gradually decomposed – not by wind or weather but by millions and millions of tiny organisms. Fungi thread their way through the dead wood and degrade cell walls. Tiny animals such as insect larvae and mites gnaw through the tissue. And something very important happens in the process: The carbon stored in the plant is released, ultimately placing it at the disposal of plants again for the purpose of photosynthesis. But what exactly is responsible for performing this task in the global ...

COPD care pathway leads to shorter hospital stays, more referrals to pulmonary rehab

2025-08-28
Miami (August 28, 2025) – Using a care pathway focused on chronic obstructive pulmonary disease (COPD) can lead to shorter hospital stays, increased referrals to pulmonary rehabilitation, and improved standardization of care, according to a new study. The study is published in the July 2025 issue of Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation, a peer-reviewed, open-access journal. COPD is an inflammatory lung disease, comprising several conditions, including chronic ...

First global guidelines for pregnancy and inflammatory bowel disease developed

2025-08-28
For women with inflammatory bowel disease (IBD), pregnancy can be an uncertain time due to limited clinical data about how IBD medications impact pregnancy outcomes and infants who have been exposed to IBD medications in utero.  As a matter of policy, pregnant women are excluded from clinical trials of experimental therapies for IBD and when a new therapy achieves regulatory approval, there is only animal safety data, but no human pregnancy safety data.   For patients with IBD, stopping medication ...

In search of the perfect raspberry

2025-08-28
One of our most popular summer soft fruits could last longer in the fridge thanks to pioneering new research conducted at Cranfield University. Researchers have recently published a new method to edit the DNA of raspberries, with the goal of creating more sustainable raspberry production and less food waste. A first for gene editing in raspberry The new study details a novel method for the isolation of single cells (protoplasts) from the leaf tissue of raspberry microplants grown in sterile tissue culture. The protoplasts were then gene edited with CRISPR-Cas9, a revolutionary biotechnology ...

Bio-inspired, self-cleaning sweat sensors for comfortable wearable health monitoring

2025-08-28
Wearable sensors can help prevent critical health issues by continuously monitoring physiological factors in real time. Specifically, sweat monitoring can provide valuable insights into electrolyte balance and overall health. Sodium concentration in sweat is a key indicator of hydration and muscle performance. Thin film materials, such as carbon nanotubes (CNTs) and ion-selective membranes (ISMs), have become central to the development of wearable sweat sensors. CNTs offer high mechanical flexibility and electrical conductivity, and ISMs enable non-invasive detection of specific ions in sweat. Unfortunately, ...

Chung-Ang University researchers reveal strange dynamics of nanoparticle growth and shrink

2025-08-28
Nanoparticles have diverse applications in modern science and industry, powering technologies like quantum-dot displays, nanocatalysts and drug delivery. Their unique physicochemical properties, which can be tuned by changing their size and shape, make them highly attractive. However, despite extensive research, the exact mechanisms and dynamics of monodisperse, or uniformly sized, nanoparticle formation and growth remain poorly understood. The classical nucleation theory (CNT), based on the Gibbs-Thomson equation, has been the primary framework for understanding nanoparticle ...

No strong evidence for alternative autism treatments, study finds

2025-08-28
The most comprehensive quantitative review of research into complementary and alternative treatments for autism has found no strong evidence to support their use, and that the safety of these treatments was rarely assessed. A new study from Paris Nanterre University, Paris Cité University and the University of Southampton, published today [28 August] in Nature Human Behaviour, assessed 248 meta-analyses, including 200 clinical trials involving over 10,000 participants. Researchers were investigating the efficacy and safety of complementary, alternative and integrative medicines (CAIMs) to treat autism. They looked at 19 types of treatment, including animal-assisted interventions, ...

New self-assembling material could be the key to recyclable EV batteries

2025-08-28
Today’s electric vehicle boom is tomorrow’s mountain of electronic waste. And while myriad efforts are underway to improve battery recycling, many EV batteries still end up in landfills. A research team from MIT wants to help change that with a new kind of self-assembling battery material that quickly breaks apart when submerged in a simple organic liquid. In a new paper published in Nature Chemistry, the researchers showed the material can work as the electrolyte in a functioning, solid-state ...

An ancient signpost: Minute fossils tell big story about arthropod evolution

2025-08-28
A tiny fossil of a sea creature that lived more than half a billion years ago sheds new light on the evolution of arthropods, the most species-rich and successful group of animals to inhabit the Earth, according to a study published in Nature Communications. One of the last remaining enigmas surrounding arthropod evolution has been the split of the tree of life separating the two largest groups of arthropods: mandibulates, the group including insects, crustaceans, millipedes and centipedes; and chelicerates, the group that includes spiders, scorpions and their kin. New analyses of fossils of an extinct segmented creature known as Jiangfengia multisegmentalis reveal ...

Predictable structures in music synchronises blood pressure the most, and could be used to create personalized music-based cardiovascular therapies  

2025-08-28
Key take-aways     New research shows that blood pressure, like heart rate and breathing, synchronises more to predictable phrase structures in music, which may improve the body’s baroreflex sensitivity, i.e. its ability to regulate blood pressure.  92 participants had their blood pressure continuously monitored while listening to nine out of 30 piano music tracks. The piece of music that had the most predictable phrase structures, and the biggest impact on blood pressure, was the English pianist Harold Bauer’s performance of Franz Liszt’s ...

New systematic review and meta-analysis shows an association between shingles vaccination and lower risk of heart attack and stroke 

2025-08-28
Key take-aways    A new global systematic review and meta-analysis has shown an association between herpes zoster vaccination, used to prevent shingles, and a statistically significant lower risk of heart attack and stroke  Herpes zoster vaccination was associated with an 18% and 16% reduction in risk of cardiovascular events in adults 18 and 50 years or older, respectively   The findings are encouraging, but more research is needed to understand whether there may be a causal connection       Madrid, Spain – 28 August 2025: A new global systematic ...

Food for thought: Using food delivery services to provide rapid cardiac arrest response and potentially save lives

2025-08-28
Inspired by an urgent need to improve timely defibrillation for out-of-hospital cardiac arrests (OHCA) in dense urban settings, a team of investigators developed a simulation that explored the potential of leveraging an existing food delivery network in Taipei City, Taiwan, to help address this challenge. Their findings in the Canadian Journal of Cardiology, published by Elsevier, suggest that deploying food delivery riders to deliver defibrillation may reduce automated external defibrillator (AED) response times by approximately three minutes—about 50% faster than a traditional emergency medical system (EMS)—and might be particularly beneficial during peak ...

College drinking linked to poor academics, mental health for those around the drinker: Study

2025-08-28
By Paul Candon PISCATAWAY, NJ – It’s well known that alcohol misuse can harm not only drinkers themselves but also those around them. Now, a new report in the Journal of Studies on Alcohol and Drugs shows that, among college students, harms such as lower grades, mental distress and even suicidal thoughts are linked to being exposed to a drinker’s poor behavior. “We often think of alcohol’s harms as physical or social, but this was the first study to assess academic harms from others’ drinking, like having to drop a class or take on extra work,” says lead researcher Pamela ...
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