Thirty-year results from the longest-running prostate cancer screening trial confirm mortality benefits that grow with time. Separate studies at the EAU26 congress show how risk-stratified MRI and the Stockholm3 blood test could cut unnecessary scans by up to 67%.

Analysis of two large U.S. insurance databases confirms that prenatal valproate exposure substantially increases risks of ADHD, autism, and other neurodevelopmental disorders, while levetiracetam and lamotrigine show no meaningful associations.

As the global cosmetic procedures market approaches $180 billion by 2033, experts argue in The BMJ that harms are increasing, especially from procedures abroad, while UK regulation lags behind reforms adopted in Australia and elsewhere.

A new chaos-theory-based encryption method protects individual medical images so they remain unreadable even if hospital networks are compromised, processing fast enough for real-time NHS use at two to four seconds per image.

A systematic review of 41 peer-reviewed papers finds that vaccine hesitancy in Canada is driven largely by structural barriers including inflexible clinic hours, ID requirements, inconsistent messaging, and chronic underfunding of community-led vaccination programs.

The first head-to-head clinical trial comparing apixaban and rivaroxaban for venous thrombosis found that rivaroxaban caused more than double the rate of clinically relevant bleeding (7.1% vs 3.3%) with no difference in clot prevention.

Researchers turned waste from traditional herbal medicine production into phosphorus-modified biochar that adsorbs lead and cadmium from contaminated soil and water while simultaneously improving crop productivity and medicinal compound concentration.

Regulatory T cells in the gut zero in on specific protein fragments from common foods like corn, soy, and wheat, actively training the immune system to tolerate them rather than attack. The finding could lead to precision therapies for food allergies.

The AAN has published its first guidance on non-FDA-cleared wearable devices for neurological care, covering epilepsy seizure detection, headache management, sleep monitoring, and cardiac screening, while warning of inaccurate readings and anxiety risks.

Former college athletes with three or more concussions scored worse on seven measures of brain health five years after graduation, though the vast majority remained within normal clinical ranges. The study included 20 sports and nearly half female participants.

Fatal police shootings of Black residents versus White residents varied enormously across U.S. states, with Utah showing the widest disparity and Mississippi the narrowest. Higher state-level gun ownership raised shooting rates for all groups but did not explain the racial gaps.

Analysis of U.S. single-parent households finds gender alone does not predict poverty. Instead, women's higher rates reflect their greater likelihood of caring for dependent children, which diminishes the poverty-reducing benefits of employment.

Researchers used a 3D-printed robotic rattlesnake at a zoo to test whether captive animals retain innate fear responses. Species that naturally coexist with rattlesnakes showed the strongest avoidance, suggesting evolutionary memory persists in captivity.

A cocktail of three common amino acids, injected alongside lipid nanoparticles, increased mRNA delivery up to 20-fold and raised CRISPR gene editing efficiency from 25% to nearly 90% in mice, potentially transforming therapies for diseases like cystic fibrosis.

A simplified nanoparticle made of just three components can reprogram T cells inside the body to destroy disease-causing B cells, potentially replacing the costly, time-consuming process of manufacturing CAR-T cells in a lab.

A study in Science Translational Medicine identifies NFAT as a residency switch for uterine natural killer cells, offering a new biological explanation for preeclampsia, implantation failure, and some early pregnancy losses.

An international team has launched an open-access 3D portal letting anyone explore intact human organs from whole-organ views down to near-cellular detail. The Human Organ Atlas contains 56 organs from 25 donors across 307 datasets.

Cornell Tech researchers found that AI writing assistants with biased autocomplete suggestions shifted users' opinions on issues like the death penalty and fracking. Neither pre-warnings nor post-debriefings reduced the effect. Published in Science Advances.

After a 2019 bleaching event in Moorea, an encrusting algae species stabilized dead coral branches on the reef while mussels and fungi hollowed them from inside. The dead structures persisted through a 2024 storm, blocking the space juvenile corals need to recolonize. Published in PLOS One.

UTEP researchers built a 3D-printed rattlesnake with real rattles and tested it on 38 captive-born zoo species. All animals showed aversion to the rattling display, but species from rattlesnake territory reacted far more strongly, suggesting an evolved, innate sensitivity. Published in PLOS One.

In the largest comparative study of its kind, Utrecht University researchers found that zoo-housed bonobos and chimpanzees show similar levels of aggression. The difference lies in who attacks whom: chimp males target everyone, while bonobo aggression flows from all directions toward males.

Dual-positive circulating cells bearing both tumor and immune markers were detected in 45% of women with advanced breast cancer. Those with three or more had median survival of 23.5 months versus 33.6 months. Published in Science Translational Medicine.

Plants pause root growth during cold and salt stress by halting cell division, then resume within 24 hours of returning to normal conditions. A gene called CDKA;1 controls this restart. The finding, published in New Phytologist, could guide engineering of climate-resilient crops.

University of Minnesota researchers showed that Marburg virus's entry protein drives cell invasion up to 300 times more efficiently than Ebola's, despite sharing the same human receptor. A nanobody that slips past the protein's protective cap blocked viral entry in lab tests. Published in Nature.

A study of over 1,000 Norwegian captains and mates found deep skepticism about autonomous ships, centered on emergency response capabilities, deskilling of crews, and whether algorithms can handle the unpredictability of the open ocean. Published in WMU Journal of Maritime Affairs.