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Rings of time: unearthing climate secrets from ancient trees

2025-06-09
Deep in the swamps of the American Southeast stands a quiet giant: the bald cypress (Taxodium distichum). These majestic trees, with their knobby “knees” and towering trunks, are more than just swamp dwellers – they’re some of the oldest living organisms in Eastern North America. Some have been around for more than 2,500 years, quietly thriving in nutrient-poor, flooded forests where most other trees would wither. But life isn’t easy for these ancient trees. They’re under siege ...

Medical AI systems failing to disclose inaccurate race, ethnicity information

2025-06-09
The inaccuracy of race and ethnicity data found in electronic health records (EHRs) can negatively impact patient care as artificial intelligence (AI) is increasingly integrated into healthcare. Because hospitals and providers inconsistently collect such data and struggle to accurately classify individual patients, AI systems trained on these datasets can inherit and perpetuate racial bias. In a new publication in PLOS Digital Health, experts in bioethics and law call for immediate standardization of methods for collection of race and ethnicity data, and for developers to warranty race and ethnicity data quality in medical AI systems. The research synthesizes concerns about why patient ...

Light and AI drive precise motion in soft robotic arm developed at Rice

2025-06-09
HOUSTON – (June 9, 2025) – Researchers at Rice University have developed a soft robotic arm capable of performing complex tasks such as navigating around an obstacle or hitting a ball, guided and powered remotely by laser beams without any onboard electronics or wiring. The research could inform new ways to control implantable surgical devices or industrial machines that need to handle delicate objects. In a proof-of-concept study that integrates smart materials, machine learning and an optical control system, a team of Rice researchers led by materials scientist Hanyu Zhu used a light-patterning device to ...

Vital connections between journalists and whistleblowers under increasing pressure

2025-06-09
Investigative journalists are facing severe challenges and threats, and their vital connections with whistleblowers are under increasing pressure, researchers have said. Legal intimidation is having a "chilling effect" and those engaged in crime and security journalism are encountering extreme risks. Experts have discussed their significant concerns about the perils many journalists face in their commitment to uncovering truth, from pervasive state surveillance to targeted prosecution and even espionage ...

Patients are opting in for 10 years of breast cancer treatment

2025-06-09
ANN ARBOR, Michigan — As recommendations suggest extending hormone-based breast cancer treatment to 10 years for some patients, a new study sheds light on whether patients are opting for it.   In a study of 591 women with early stage breast cancer who completed five years of endocrine therapy, 47% decided to continue the treatment. Patients with stage 2 disease were more likely to continue, with 62% agreeing, compared to 39% of patients with stage 1 cancer.   The study, led by researchers at the University of Michigan Rogel Cancer Center and Stanford Medicine, was published in the Journal of the National Cancer Institute.   Endocrine ...

Center for Bioenergy Innovation taps Cregger, Eckert as chief science officers

2025-06-09
The Center for Bioenergy Innovation, or CBI, at the Department of Energy’s Oak Ridge National Laboratory has promoted Melissa Cregger and Carrie Eckert to serve as chief science officers, advancing the center’s mission of innovations for new domestic biofuels, chemicals and materials. Cregger will oversee CBI’s development of resilient, high-yielding, non-food feedstock crops, while Eckert will guide the center’s research on cost-effective methods to break down and convert plant biomass into valuable fuels and products. Brian Davison, chief scientist for biotechnology at ORNL and formerly chief science officer for the center, ...

Anthropologists map Neanderthals’ long and winding roads across Europe and Eurasia

2025-06-09
Recent scholarship has concluded that Neanderthals made a second major migration from Eastern Europe to Central and Eastern Eurasia between 120,000 and 60,000 years ago. But the routes they took have long been a mystery—primarily because there are few archaeological sites connecting the two regions.  In a new analysis, a team of anthropologists—using computer simulations—has offered a map of possible pathways, which concludes Neanderthals likely used river valleys as natural highways and traveled during warmer periods to move approximately 2,000 miles (3,250 km) in less than 2,000 years.  “Our findings show that, despite obstacles like mountains ...

Stress genes clear dead cells, offering disease insights

2025-06-09
A new study from The University of Texas at Arlington details a novel strategy for how the body clears out dead cells during stress, revealing unexpected roles for well-known stress-response genes—a discovery that could help scientists better understand diseases affecting the immune system, brain and metabolism.   “The body is constantly creating new cells and removing old cells once they die,” said Aladin Elkhalil, lead author of the study and a third-year doctoral student in the lab of Piya Ghose, ...

Healthy sleep patterns in adolescence predict better cardiovascular health in the future

2025-06-09
DARIEN, IL – A new study to be presented at the SLEEP 2025 annual meeting found that teens with earlier, more efficient, and less variable sleep patterns at age 15 had better cardiovascular health at age 22. Results show that several healthy sleep habits at age 15 predicted a higher (better) cardiovascular health score at age 22: falling asleep and waking up earlier, spending a lower percentage of time in bed awake, and having lower variability in total sleep time and sleep onset. In contrast, average total sleep time did not predict future cardiovascular health. Results were adjusted for potential confounders ...

A study led by CIC bioGUNE delves into the complexity of the most aggressive form of prostate cancer

2025-06-09
Cancer cannot be understood as a single, uniform disease. The more we delve into studying each type of tumor, the more we recognize the need to subclassify the disease. This concept has led to what we now call precision oncology, characterizing the molecular features of a patient's specific cancer to determine the most effective treatment. Prostate cancer is considered the most prevalent tumor among men, and it typically has a high cure rate. As such, although many men will be diagnosed with this cancer, the majority will be cured. "However, when we refer ...

Effects of psilocybin on religious and spiritual attitudes and behaviors in clergy from major world religions

2025-06-09
A new study in the peer-reviewed journal Psychedelic Medicine showed that psilocybin administration in a sample of clergy from major world religions increased multiple domains of overall psychological well-being, including positive changes in religious attitudes and behavior as well as effectiveness in their vocation as a religious leader. Click here to read the article now. The late Roland Griffiths, of Johns Hopkins University, along with Stephen Ross and Anthony Bossis, from New York University Grossman School ...

Investigating how stress may cause sleep and memory deficits

2025-06-09
Stress worsens sleep quality and can impair memory. Shinjae Chung, from the University of Pennsylvania, led a study to explore a neural pathway in male mice that stress may influence to cause sleep and memory disturbances.   In their JNeurosci paper, the researchers artificially activated neurons in the paraventricular nucleus of the hypothalamus (PVN) that were previously linked to stress. This experimental manipulation made mice sleep less and impaired how well mice performed in a memory task. Notably, when mice were stressed, artificially inhibiting these PVN neurons reduced stress-related memory ...

Researchers find thousands of pediatric firearm deaths linked to more permissive state gun laws

2025-06-09
Guns are now the leading cause of death for youth in the United States. Researcher from Mass General Brigham investigated whether firearm mortality rates among U.S. children ages 0-17 changed in the 13 years following a 2010 Supreme Court ruling that applied the Second Amendment to state and local governments. In states with the most permissive firearm laws, they found evidence of 6,029 more pediatric deaths due to firearms than would have been expected based on the existing demographic trends—and more than 1,400 excess ...

Landmark test for coeliac disease promises to take away the pain of diagnosis

2025-06-09
Imagine having to eat something that makes you sick – just to see what’s making you ill in the first place.  That’s the harsh reality of current diagnostic tests for coeliac disease, which require people to eat large amounts of gluten for weeks in order to get an accurate diagnosis. But this painful process could soon be a thing of the past, with WEHI researchers and industry partner Novoviah Pharmaceuticals developing a world-first blood test that can identify the condition in patients – even when they’re on gluten-free diets.   At a glance New clinical research published in the high-impact ...

A recipe for success: beefing up the taste of cultured meat with amino acids

2025-06-09
Tokyo, Japan – Across the world the demand for meat is growing, despite associated environmental and animal welfare costs. Although lab-grown – or cultured – meat could be part of the answer, scientists have yet to perfect one crucial detail: the taste. In an article to be published in Food Chemistry, researchers from the Institute of Industrial Science, The University of Tokyo, have measured and found a way to control the key amino acids responsible for flavor in a step toward making cultured meat taste just like the real thing. The push toward cultured meat has been adopted because conventional production is not a sustainable solution for ...

Protecting peppers from devastating viral diseases through gene pyramiding

2025-06-09
Even with today’s advanced agricultural technologies, plant diseases can still be extremely devastating to crops, causing billions of dollars in losses worldwide every year. Begomoviruses represent a prominent example of this threat—these whitefly-transmitted pathogens cause yellow leaf curl disease in peppers and can destroy up to 100% of fruit yield in affected fields across Asia, Africa, and the Americas. Breeding crops that are resistant to begomoviruses has long been the most effective and widely used strategy for preventing such massive losses. Though usually effective, this approach has serious limitations, especially when dealing with mixed infections. Scientists ...

Lizards of Madagascar

2025-06-09
Kyoto, Japan -- After the island of Madagascar drifted away from India 88 million years ago, isolating it from all other landmasses, its flora and fauna evolved in seclusion. As these transformed into plants and animals completely unique to their island, Madagascar became a biodiversity hotspot unlike anywhere else on Earth. An important facet of this biodiversity is an ecological process called endozoochory, which is when animals eat plant seeds and then poop them out somewhere else, aiding in the spread of the plants. Most research on endozoochory has focused on the roles of ...

Beyond the brain: how BCIs are rewiring medicine and redefining humanity

2025-06-09
Brain-computer interface (BCI) technology is opening an unprecedented chapter in human-machine integration by establishing direct communication between the brain and external devices. Once a science fiction concept, BCI is now reshaping the landscape of neurosurgery and neurorehabilitation. By decoding brain signals to restore lost motor, sensory, and language functions, BCIs offer new hope for individuals affected by paralysis, aphasia, and neurodegenerative diseases. But their impact extends well beyond the clinic—BCIs are poised to influence cognition, ethical governance, and national security. As this disruptive technology matures, ...

Fossilized dinosaur gut shows that sauropods barely chewed

2025-06-09
Plant fossils found in the abdomen of a sauropod support the long-standing hypothesis that these dinosaurs were herbivores, finds a study publishing June 9 in the Cell Press journal Current Biology. The dinosaur, which was alive an estimated 94 to 101 million years ago, ate a variety of plants and relied almost entirely on its gut microbes for digestion.   “No genuine sauropod gut contents had ever been found anywhere before, despite sauropods being known from fossils found on every continent and despite the group ...

School dental treatments stop kids’ tooth decay in its tracks

2025-06-09
Two topical treatments applied to kids’ cavities can stop the majority of them from progressing for years, according to a study led by NYU College of Dentistry and published in JAMA Network Open. Treating more than 10,000 cavities in New York City elementary school students, the researchers found that both atraumatic restorations (ART) and silver diamine fluoride (SDF) kept most dental decay from worsening, supporting the use of non-surgical approaches for managing cavities. Children miss an estimated 34 million hours of school each year due to emergency dental care. Bringing cavity prevention programs to schools can improve kids’ oral health and stave ...

How high is your dementia risk? It might depend on where you live

2025-06-09
In one of the largest and most comprehensive studies of its kind, a research team led at UC San Francisco has identified the regions where dementia occurs most often.  What They Discovered Using the Mid-Atlantic* as the basis for comparison, researchers found that dementia rates were 25% higher in the Southeast.** The Northwest*** and Rocky Mountains**** were both 23% higher, and the South***** was 18% higher. The Southwest, which includes California, was 13% higher; while the Northeast, which includes New York, was 7% higher.  These differences remained when researchers accounted for factors like age, ...

Firearm laws and pediatric mortality in the US

2025-06-09
About The Study: The results of this study demonstrate that permissive firearm laws contributed to thousands of excess firearm deaths among children living in states with permissive policies. Future work should focus on determining which types of laws conferred the most harm and which offered the most protection.  Corresponding Author: To contact the corresponding author, Jeremy Samuel Faust, MD, MS, email jsfaust@bwh.harvard.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamapediatrics.2025.1363) Editor’s ...

Use of the 988 Suicide and Crisis Lifeline at national, regional, and state levels

2025-06-09
About The Study: The findings of this cross-sectional study suggest that although 988 has been contacted more than 16 million times since its launch in July 2022, there remains opportunity to increase 988 use. Corresponding Author: To contact the corresponding author, Jonathan Purtle, DrPH, MSc, email jonathan.purtle@nyu.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2025.14323) Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, ...

Location of firearm suicides in the United States

2025-06-09
About The Study: This study found that nearly 1 in 5 firearm suicides in the U.S. occurred outside the home, highlighting the potential to enhance intervention strategies by extending them to broader community settings. Corresponding Author: To contact the corresponding author, Camerin A. Rencken, PhD, ScM, email crencken@uw.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2025.14423) Editor’s Note: Please see the article for additional information, including other authors, author contributions ...

Discovery suggests method to offset antibiotic-caused harm to infant immune systems

2025-06-09
In 2017, scientists at Cincinnati Children’s revealed that using antibiotics to protect newborns from dangerous infections often comes with a long-term consequence—a permanently underdeveloped immune system that can make children prone to poor outcomes from future lung infections. Now a study published June 9, 2025, in Cell, details the mechanisms behind antibiotic-related immune disruptions, which in turn suggests a way to reverse or minimize the risk. "These remarkable findings indicate that we might be able to protect at-risk infants through targeted supplementation," says senior author Hitesh Deshmukh, MD, PhD, a neonatologist with the Perinatal ...
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