Johns Hopkins scientists engineer nanoparticles able to seek and destroy diseased immune cells
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Johns Hopkins Medicine scientists say they have developed a simplified version of biodegradable nanoparticles that can “educate” the immune system to find and destroy disease-causing cells throughout the body. The study, they say, advances the field of engineering immune cells within a patient’s own body to combat cancers and autoimmune diseases including lupus, among other conditions.
Engineered immune cells have been successfully used to treat an array of blood cancers, using CAR-T cells, or chimeric antigen receptor T cells. The treatment ...