NYU researchers found that early life stress alters gut-brain communication through multiple pathways, with mouse experiments showing sex-specific motility changes and human studies of 52,000+ children linking maternal depression and childhood adversity to increased digestive disorders.

Researchers identified a single odorant receptor, OR49, that allows Aedes aegypti mosquitoes to detect and avoid borneol, a plant-derived repellent compound. Knocking out the gene eliminated both the neural response and avoidance behavior, opening a path to designing more effective repellents.

The Deep Underground Neutrino Experiment will generate datasets so massive that traditional analysis cannot keep up. A first-of-its-kind workshop at Rice University mapped out how AI and machine learning will be integrated into DUNE's computing ecosystem.

A study of nine Amazonian cocoa clones found that fermentation reduces sugars by 95% and tannins by nearly 50% while boosting amino acids and minerals, leading researchers to propose fermented-unfermented blends that balance flavor with nutritional value.

Colorado State University plant pathologists identified four Fusarium species responsible for potato dry rot in the San Luis Valley, including one not previously found in the U.S., providing critical data for targeted disease management in one of the nation's top potato-producing regions.

UCLA researchers developed a universal CAR-NKT cell therapy targeting mesothelin that achieved complete tumor elimination in mouse models of endometrial cancer, can be manufactured at roughly $5,000 per dose, and may work against breast, ovarian, pancreatic, and lung cancers using the same product.

Montana State University microbiologists will use a $1.9 million USDA grant to develop organoid models of the chicken intestine, examining how highly pathogenic avian influenza damages cells at a level of detail that could reveal new prevention strategies.

Across four experiments with over 380 participants, University of Mississippi researchers found that weaving random nouns into stories produced recall rates equal to or better than survival processing, suggesting both techniques tap the same evolved cognitive machinery.

A 3D-printed scaffold made from chitosan and plant-derived antimicrobials delivers sustained germ-fighting action to chronic wounds while biodegrading into the skin, avoiding both organic solvents and the antibiotic resistance risks of conventional treatments.

A 37-year Smithsonian field study in Chesapeake Bay found that cannibalism by adult blue crabs is the sole source of predation on juveniles in mid-salinity rivers, but crabs in the shallowest waters are only 30% likely to be eaten compared to 60-80% in deeper zones.

A new liquid biopsy platform called cf-EpiTracing captures detailed epigenetic signatures from trace blood samples, identifying disease-driving tissues, distinguishing lymphoma subtypes, and detecting colorectal cancer with up to 97.6% accuracy in training cohorts.

Comparing 32 adults with ADHD to 31 neurotypical controls, researchers found that ADHD participants exhibited significantly more sleep-like brain activity during sustained attention tasks, and this activity correlated with more errors, slower reactions, and greater sleepiness.

Researchers at the University of Barcelona have identified a brain pathway connecting auditory regions directly to a fear-processing center, enabling rapid unconscious responses to alarming sounds - paralleling a similar route already known for visual threats.

Analysis of 2,300+ seawater samples spanning the Pacific, Atlantic, and Indian Oceans shows that industrial chemicals make up the bulk of human-derived organic matter in coastal waters, reaching 20% of total signals near shorelines and exceeding 50% at polluted river mouths.

Two BrainGate trial participants - one with ALS and one with spinal cord injury - used an implantable brain-computer interface to type via imagined finger movements on a virtual QWERTY keyboard, with one reaching 22 words per minute at 98.4% word accuracy.

Researchers at Sanford Burnham Prebys trained a computational model called TLPath on 5,263 histopathology slides to predict telomere length from tissue images alone, outperforming age-based predictions and potentially transforming aging research.

Treatment delays beyond 90 days for early-onset colorectal cancer were more common in urban areas than expected, with young male, Black, Hispanic, and Asian or Pacific Islander patients disproportionately affected, challenging assumptions about urban healthcare access.

A systematic review and meta-analysis of 42 studies across 12 high-income countries found a relative increase in both healthcare visits for self-injury and self-reported self-harm among children and youth, with female individuals disproportionately affected.

The PARADIGM phase 2b trial found PrimeC safe in ALS patients, with exploratory results showing a 2.23-point functional advantage at 6 months that widened to 7.92 points at 18 months, plus a 64% reduced risk of hospitalization, respiratory failure, or death.

A randomized trial found that continuing GLP-1/GIP agonists before upper endoscopy increased clinically significant residual gastric volume, but a clear-liquid diet the day before may mitigate the risk regardless of medication use.

A 140-patient NIH-supported trial found that weekly injectable extended-release buprenorphine produced significantly higher rates of illicit opioid abstinence during pregnancy than daily sublingual buprenorphine, with fewer serious adverse events and comparable neonatal outcomes.

Insilica's ToxIndex platform uses AI agents to orchestrate over 600 toxicology models and a 60-billion-triple knowledge graph, producing traceable risk assessments that could reshape how chemicals and drugs are evaluated for safety.

A new polygenic risk score built from 20 metabolic traits and multi-ancestry genetic data predicts type 2 diabetes, obesity, and downstream complications better than existing models, identifying people twice as likely to need GLP-1 drugs or bariatric surgery.

A Guilin University team created lead-free tungsten bronze ceramics that achieve 7.93 J/cm3 energy density at 94.25% efficiency with ultrafast 1.56-microsecond discharge times, maintaining performance across a 30-180 degrees C temperature range.

Researchers used machine learning to screen 660,000 candidate compositions and identified a BaTiO3-based high-entropy ceramic that achieves an energy storage density of 10.8 J per cubic cm with 86% efficiency - a result enabled by its unusual position between two types of ferroelectric behavior.