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Diatom surprise could rewrite the global carbon cycle

2024-07-17
When it comes to diatoms that live in the ocean, new research suggests that photosynthesis is not the only strategy for accumulating carbon. Instead, these single-celled plankton are also building biomass by feeding directly on organic carbon in wide swaths of the ocean. These new findings could lead researchers to reduce their estimate of how much carbon dioxide diatoms pull out of the air via photosynthesis, which in turn, could alter our understanding of the global carbon cycle, which is especially relevant given the changing climate.   This research is led by bioengineers, bioinformatics experts and other genomics researchers ...

Microbes found to destroy certain ‘forever chemicals’

Microbes found to destroy certain ‘forever chemicals’
2024-07-17
UC Riverside environmental engineering team has discovered specific bacterial species that can destroy certain kinds of “forever chemicals,” a step further toward low-cost treatments of contaminated drinking water sources. The microorganisms belong to the genus Acetobacterium and they are commonly found in wastewater environments throughout the world.  Forever chemicals, also known as per- and polyfluoroalkyl substances or PFAS, are so named because they have stubbornly strong carbon-fluorine chemical bonds, which make them persistent in the environment.  The microorganisms discovered by UCR scientists and their collaborators ...

When the brain speaks, the heart feels it

2024-07-17
Research by the Technion has demonstrated that activation of the brain’s reward system could boost recovery from a heart attack. The research, which was conducted at the Ruth and Bruce Rappaport Faculty of Medicine, was led by Ph.D. student Hedva Haykin under the supervision of Prof. Asya Rolls and Prof. Lior Gepstein. The Technion research group focused on the reward system, a brain network activated in positive emotional states and motivation and evaluated its potential in improving recovery ...

Llama nanobodies: A breakthrough in building HIV immunity

2024-07-17
ATLANTA — A research team at Georgia State University has developed tiny, potent molecules that are capable of targeting hidden strains of HIV. The source? Antibody genes from llama DNA. The research, led by Assistant Professor of Biology Jianliang Xu, uses llama-derived nanobodies to broadly neutralize numerous strains of HIV-1, the most common form of the virus. A new study from this team has been published in the journal Advanced Science. “This virus has evolved a way to escape our immune system. Conventional antibodies are bulky, so it’s difficult for them to find and attack the virus’ surface,” ...

How our brains learn new athletic skills fast

2024-07-17
You join a swing dance class, and at first you’re all left feet. But – slowly, eyes glued to the teacher – you pick up a step or two and start to feel the rhythm of the big band beat. A good start. Then you look over and realize the couple next to you has picked up twice the steps in half the time. Why? According to a new study from University of Florida biomechanical researchers, the quick, athletic learners among us really are built differently – inside their brains. That’s what UF Professor of Biomedical Engineering Daniel Ferris, Ph.D., and his former doctoral student, Noelle Jacobsen, Ph.D., discovered when they studied how people learn ...

New Durham University study shows promising diagnosis of Multiple Sclerosis from images of the eye

2024-07-17
-With images- Researchers at Durham University, UK and Isfahan University of Medical Sciences, Iran have developed an innovative approach to diagnosing Multiple Sclerosis using advanced eye imaging techniques. This groundbreaking method could revolutionise how Multiple Sclerosis is detected, offering a faster, less invasive, and more accessible alternative to current diagnostic procedures. The study, led by Dr Raheleh Kafieh of Durham University, integrates two types of eye scans: optical coherence tomography (OCT) and infrared scanning laser ophthalmoscopy (IR-SLO). By training computer models ...

New training program facilitates home-based transcranial electrical stimulation

2024-07-17
Traveling to and from a clinic or a laboratory for treatment can be difficult and expensive for older Americans. To address this, scientists developed and tested a new training and supervision program for older adults so they can receive Transcranial Electrical Stimulation (tES), a promising intervention for various clinical conditions, in their homes. Published in Neuromodulation: Technology at the Neural Interface, this groundbreaking training and supervision program was designed to introduce and teach caregivers, family members, and patients how to administer home-based transcranial electrical stimulation (HB-tES), equipping them ...

Study finds persistent proteins may influence metabolomics results

2024-07-17
GRAND RAPIDS, Mich. (July 17, 2024) — Van Andel Institute scientists have identified more than 1,000 previously undetected proteins in common metabolite samples, which persist despite extraction methods designed to weed them out.   The findings, published in Nature Communications, give scientists new insights and tools for improving future metabolomics experiments, including a novel protocol for removing these proteins during the extraction process. The study does not invalidate prior results but instead reinforces the importance ...

Living in greener neighborhoods during midlife can slow cognitive decline

2024-07-17
A new study found that increased exposure to residential greenery may help stave off cognitive decline by an annual rate of eight months. This delay was observed more among people living in low-socioeconomic status and highly populated neighborhoods, as well as people who carry the APOE-ɛ4 gene, which is associated with an increased risk of Alzheimer’s disease. Research has shown that about 40 percent of dementia could be prevented or delayed worldwide by addressing modifiable risk factors associated with the condition, particularly during midlife.  A new study led by a Boston University School of Public Health (BUSPH) ...

Research tracks 66 million years of mammalian diversity

Research tracks 66 million years of mammalian diversity
2024-07-17
When trying to understand the present, it's helpful to look to history. New research from the University of Nebraska–Lincoln examined the fossil record going back 66 million years and tracked changes to mammalian ecosystems and species diversity on the North American continent.  The study, led by Alex Shupinski, who earned her doctorate in May, and co-authored by Kate Lyons, associate professor in the School of Biological Sciences, provides a large-scale view of how species diversity changed over the first 65 million years of the Cenozoic era — up until the arrival of humans — ...

RegeneratOR Test Bed welcomes Cytoink to accelerate biomedical innovations

RegeneratOR Test Bed welcomes Cytoink to accelerate biomedical innovations
2024-07-17
Winston-Salem, North Carolina — July 17, 2024 — The RegeneratOR Test Bed, located in Innovation Quarter, announces the inclusion of Cytoink into its pioneering ecosystem dedicated to advancing biomedical research and development. Cytoink brings cutting-edge biomaterials manufacturing, with over 100 custom formulations, and bioprinting expertise that merges biofunctionality with high-throughput production. Cytoink specializes in the biofabrication of in vitro 3D tissue phantoms, extrusion-based and light-based (DLP/VAM) bioinks, and integrated perfusion microfluidics bioreactors. Additionally, Cytoink provides bespoke biomaterial solutions ...

Jeffrey Spraggins named director of Vanderbilt University Mass Spectrometry Research Center

Jeffrey Spraggins named director of Vanderbilt University Mass Spectrometry Research Center
2024-07-17
Jeffrey Spraggins, associate professor of cell and developmental biology, biochemistry, and chemistry, has been named director of the Mass Spectrometry Research Center. He succeeds Richard Caprioli, Stanford Moore Chair in Biochemistry, who established the MSRC in 1998 and who is retiring this summer. Spraggins is a leading scientist in spatial biology and imaging mass spectrometry—an untargeted molecular imaging approach that enables molecular mapping at cellular resolution—a technology originated by Caprioli. Spraggins’ research lies at the intersection of technology development, data science, and biomedical research. His research group ...

Duke-NUS finding advances quest to slow ageing

Duke-NUS finding advances quest to slow ageing
2024-07-17
An ageing population will bring colossal health, social, and economic challenges over the coming decades[1]. As people live longer, staving off the physical decline and frailty that come with age has become a holy grail, with effective interventions projected to unlock significant societal and economic benefits. Estimates suggest that a slowdown in ageing that increases life expectancy by one year alone is worth US$38 trillion.[2]  In a discovery published in Nature, a team of scientists from Duke-NUS Medical School in Singapore may have found a key to slow ageing. The ...

Logged forests can still have ecological value – if not pushed too far

Logged forests can still have ecological value – if not pushed too far
2024-07-17
Researchers have analysed data from 127 studies to reveal ‘thresholds’ for when logged rainforests lose the ability to sustain themselves. The results could widen the scope of which forests are considered ‘worth’ conserving, but also show how much logging degrades forests beyond the point of no return. The first-of-its-kind study, led by researchers from the Department of Life Sciences at Imperial College London with collaborators from around the world, is published today in ...

Exoplanet caught in ‘hairpin turn’ signals how high-mass gas giants form

Exoplanet caught in ‘hairpin turn’ signals how high-mass gas giants form
2024-07-17
UNIVERSITY PARK, Pa. — Astronomers have discovered a planet that has the most oblong orbit ever found among transiting planets. The exoplanet’s extreme circuit — which looks closer to a cucumber than a circle — follows one of the most drastically stretched-out orbits of all known exoplanets, planets that orbit stars outside our solar system. It is also orbiting its star backwards, lending insight into the mystery of how close-in massive gas planets, known as hot Jupiters, form, stabilize and evolve over time. The research, led by Penn State scientists, was published today (July 17) in ...

Switching off inflammatory protein leads to longer, healthier lifespans in mice

Switching off inflammatory protein leads to longer, healthier lifespans in mice
2024-07-17
Scientists at the Medical Research Council Laboratory of Medical Science and Imperial College London have discovered that ‘switching off’ a protein called IL-11 can significantly increase the healthy lifespan of mice by almost 25%. The scientists, working with colleagues at Duke-NUS Medical School in Singapore, tested the effects of IL-11 by creating mice that had the gene producing IL-11 (interleukin 11) deleted. This extended the lives of the mice by over 20% on average. They also treated 75-week-old mice – equivalent to the age of about 55 years in humans – with an ...

New gene therapy for muscular dystrophy offers hope

New gene therapy for muscular dystrophy offers hope
2024-07-17
A new gene therapy treatment for Duchenne muscular dystrophy shows promise of not only arresting the decline of the muscles of those affected by this inherited genetic disease, but perhaps, in the future, repairing those muscles. The UW Medicine-led research focuses on delivering a series of protein packets inside shuttle vectors to replace the defective DMD gene within the muscles. The added genetic code will then start producing dystrophin, the protein lacking in patients with muscular dystrophy.  Currently, there is no cure for the disease ...

Scientists bridge the 'valley of death' for carbon capture technologies

Scientists bridge the valley of death for carbon capture technologies
2024-07-17
A major obstacle for net zero technologies in combatting climate change is bridging the gap between fundamental research and its application in the real world. This gap, sometimes referred to as ‘the valley of death’, is common in the field of carbon capture, where novel materials are used to remove carbon dioxide from flue gasses produced by industrial processes. This prevents carbon from entering the atmosphere, helping to mitigate the effects of climate change. Chemists have proposed and ...

Genome recording makes living cells their own historians

Genome recording makes living cells their own historians
2024-07-17
Genomes can now be entrusted to store information about a variety of transient biological events inside of living cells, as they happen, like a flight recorder collecting data from an aircraft. “Our method, which goes by the acronym ENGRAM, aims to turn cells into their own historians,” said Dr. Jay Shendure, a professor of genome sciences at the University of Washington School of Medicine and scientific director of the Brotman Baty Institute for Precision Medicine. Shendure led the effort, together with Wei Chen, a former graduate student, and Junhong Choi, a former postdoctoral fellow. Junhong ...

USC Schaeffer Institute launches new initiative to improve public policy through behavioral science

2024-07-17
The USC Schaeffer Institute for Public Policy & Government Service announced a new initiative today that leverages behavioral science to create more effective public policy. The Behavioral Science & Policy Initiative at the USC Schaeffer Institute will conduct research to understand people’s beliefs and behaviors to create policies and communication that better fit people’s needs. The initiative will focus on policy topics such as climate change, health, and food insecurity. “We want to help policymakers make a difference,” said Wändi Bruine de Bruin, the initiative’s ...

Groundwater is key to protecting global ecosystems

Groundwater is key to protecting global ecosystems
2024-07-17
(Santa Barbara, Calif.) — Where hidden water tables meet the Earth’s surface, life can thrive even in the driest locations. Offering refuge during times of drought, shallow groundwater aquifers act like water savings accounts that can support ecosystems with the moisture required to survive, even as precipitation dwindles. As climate change and human water use rapidly deplete groundwater levels around the world, scientists and policy makers need better data for where these groundwater-dependent ecosystems exist. Now, a new study maps ...

A new approach to accelerate the discovery of quantum materials

A new approach to accelerate the discovery of quantum materials
2024-07-17
– By Michael Matz Researchers at the Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab) and several collaborating institutions have successfully demonstrated an innovative approach to find breakthrough materials for quantum applications. The approach uses rapid computing methods to predict the properties of hundreds of materials, identifying short lists of the most promising ones. Then, precise fabrication methods are used to make the short-list materials and further ...

Influenza viruses can use two ways to infect cells

Influenza viruses can use two ways to infect cells
2024-07-17
Most influenza viruses enter human or animal cells through specific pathways on the cells’ surface. Researchers at the University of Zurich have now discovered that certain human flu viruses and avian flu viruses can also use a second entry pathway, a protein complex of the immune system, to infect cells. This ability helps the viruses infect different species – and potentially jump between animals and humans. The majority of type A influenza viruses circulating in birds and pigs aren’t normally a health ...

Engineering resilience: Advanced FEM enhances earthquake impact assessment

Engineering resilience: Advanced FEM enhances earthquake impact assessment
2024-07-17
In a significant advancement for geotechnical engineering, a refined space-time finite element method (v-ST/FEM) has been introduced to tackle the complex dynamics of soil-structure interaction during seismic events. This new approach allows for more accurate simulations of the response of earth structures to earthquake vibrations, marking a crucial step in improving infrastructure resilience against natural disasters. Designing structures like dams, tunnels, and embankments to withstand transient loads from sources such as earthquakes, high-speed trains, and explosions requires robust dynamic soil-structure interaction (SSI) analysis. Traditional methods often fall short in handling ...

The Vps21 signaling pathway regulates white-opaque switching and mating in Candida albicans

2024-07-17
This study was led by Dr. Guanghua Huang (School of Life Sciences, Fudan University). The team discovered that the conserved Vps21 signaling pathway plays critical roles in the regulation of white-opaque switching and mating in Candida albicans, a major human fungal pathogen.   Candida albicans is able to cause cutaneous diseases as well as life-threatening systemic infections in humans. It has multiple cellular morphologies and can undergo transitions among different morphologies to adapt to environmental changes. White-opaque transitions represent a typical morphological phenotypic switching system ...
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