The largest systematic review of cannabinoids for mental health conditions - covering 54 randomized controlled trials over 45 years - found no evidence that medicinal cannabis effectively treats depression, anxiety, or PTSD, while noting limited potential benefits for cannabis dependence, insomnia, and tics.

Modeling data from 156 countries projects that climate-driven heat could cause 0.47 to 0.70 million additional premature deaths annually by 2050, as rising temperatures push populations - especially in Central America, sub-Saharan Africa, and Southeast Asia - into dangerous levels of physical inactivity.

A transdisciplinary review in The Lancet draws on biological, behavioral, and social sciences to show that fathers' health - including weight, substance use, mental health, and even childhood adversity - independently influences pregnancy outcomes and child health, challenging the exclusive focus on mothers in preconception care.

A Lancet study surveying over 5,000 people from 13 countries identified the health and social indicators needed for the first global system to monitor preconception health, finding remarkable cross-country consensus that mental health, physical health, supportive relationships, and finances matter most before pregnancy.

A study in The Lancet Global Health found that climate action consistent with a 2-degree-Celsius target could prevent 13.5 million premature deaths from air pollution by 2050, but equity-based policies that shift mitigation costs to rich nations inadvertently reduce those health gains in developing countries - unless paired with targeted air pollution controls.

A six-year study of 184 bull sharks at Fiji's Shark Reef Marine Reserve found that these predators form selective social relationships, preferring partners of similar size and actively avoiding certain individuals - upending the long-held view of sharks as solitary hunters.

A study of 919 autopsy-confirmed dementia patients found that people carrying both Alzheimer's and frontotemporal lobar degeneration show a distinct cluster of neuropsychiatric symptoms - including anxiety, delusions, and personality change - that could allow clinicians to diagnose the combination during life rather than only after death.

By simulating the formation of a large crater near asteroid 16 Psyche's north pole, University of Arizona researchers generated predictions about the asteroid's interior structure that NASA's arriving spacecraft can test in 2029 - with porosity emerging as a surprisingly important variable.

Researchers developed a biochar-enhanced photocatalyst that degraded more than 98% of sulfadiazine in water within one hour under simulated sunlight - over three times faster than conventional catalysts - and maintained strong performance through five reuse cycles.

The American College of Physicians is supporting the AAP's independently developed 2026 childhood vaccine schedule over the CDC's newly issued guidance, which ACP says abandons long-standing science-based standards by adopting a more limited approach modeled on the Danish schedule.

One in four University of Hawaii students experienced period poverty in the past year, but the rate reached 51% among Native Hawaiians and 41% among Filipina students, with those affected reporting high levels of food insecurity (42%), housing insecurity (45%), and depressive symptoms (23%).

The American College of Cardiology will host a free community health fair at the Treme Recreation Center on March 21, offering cardiovascular screenings, health education, and resources - prioritizing early detection in a community with elevated heart disease risk.

Mice exposed to both stress and heavy alcohol use in early adulthood showed persistent oxidative damage in the locus coeruleus and reduced cognitive flexibility at middle age, even after prolonged abstinence - mirroring markers seen in early Alzheimer's disease.

NYU researchers found that early life stress alters gut-brain communication through multiple pathways, with mouse experiments showing sex-specific motility changes and human studies of 52,000+ children linking maternal depression and childhood adversity to increased digestive disorders.

Researchers identified a single odorant receptor, OR49, that allows Aedes aegypti mosquitoes to detect and avoid borneol, a plant-derived repellent compound. Knocking out the gene eliminated both the neural response and avoidance behavior, opening a path to designing more effective repellents.

The Deep Underground Neutrino Experiment will generate datasets so massive that traditional analysis cannot keep up. A first-of-its-kind workshop at Rice University mapped out how AI and machine learning will be integrated into DUNE's computing ecosystem.

A study of nine Amazonian cocoa clones found that fermentation reduces sugars by 95% and tannins by nearly 50% while boosting amino acids and minerals, leading researchers to propose fermented-unfermented blends that balance flavor with nutritional value.

Colorado State University plant pathologists identified four Fusarium species responsible for potato dry rot in the San Luis Valley, including one not previously found in the U.S., providing critical data for targeted disease management in one of the nation's top potato-producing regions.

UCLA researchers developed a universal CAR-NKT cell therapy targeting mesothelin that achieved complete tumor elimination in mouse models of endometrial cancer, can be manufactured at roughly $5,000 per dose, and may work against breast, ovarian, pancreatic, and lung cancers using the same product.

Montana State University microbiologists will use a $1.9 million USDA grant to develop organoid models of the chicken intestine, examining how highly pathogenic avian influenza damages cells at a level of detail that could reveal new prevention strategies.

Across four experiments with over 380 participants, University of Mississippi researchers found that weaving random nouns into stories produced recall rates equal to or better than survival processing, suggesting both techniques tap the same evolved cognitive machinery.

A 3D-printed scaffold made from chitosan and plant-derived antimicrobials delivers sustained germ-fighting action to chronic wounds while biodegrading into the skin, avoiding both organic solvents and the antibiotic resistance risks of conventional treatments.

A 37-year Smithsonian field study in Chesapeake Bay found that cannibalism by adult blue crabs is the sole source of predation on juveniles in mid-salinity rivers, but crabs in the shallowest waters are only 30% likely to be eaten compared to 60-80% in deeper zones.

A new liquid biopsy platform called cf-EpiTracing captures detailed epigenetic signatures from trace blood samples, identifying disease-driving tissues, distinguishing lymphoma subtypes, and detecting colorectal cancer with up to 97.6% accuracy in training cohorts.

Comparing 32 adults with ADHD to 31 neurotypical controls, researchers found that ADHD participants exhibited significantly more sleep-like brain activity during sustained attention tasks, and this activity correlated with more errors, slower reactions, and greater sleepiness.