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Johns Hopkins researchers show novel immune system boost helps fight cancer cells

2025-09-30
In experiments with mouse models of breast, pancreatic, and muscle cancers, researchers at Johns Hopkins All Children’s Hospital report new evidence that a novel means of boosting the natural immune system prevents cancer recurrence and improves survival.     The study, published Sept. 2 in Nature Immunology, was federally funded by the National Cancer Institute/NIH. Malignant tumors are often described as immune-suppressive or “immune cold,” meaning the patient’s immune system does not recognize or attack ...

AI model for imaging-based extranodal extension detection and outcome prediction in HPV−positive oropharyngeal cancer

2025-09-30
About The Study: This single-center cohort study found that an artificial intelligence (AI)-driven pipeline can successfully automate lymph node segmentation and imaging-based extranodal extension (iENE) classification from pretreatment computed tomography scans in human papillomavirus (HPV)-associated oropharyngeal carcinoma. Predicted iENE was independently associated with worse oncologic outcomes. External validation is required to assess generalizability and the potential for implementation in institutions ...

Frequent wildfires, heat intensify air quality issues in American megacities such as New York City

2025-09-30
Air quality in America’s largest cities has steadily improved thanks to tighter regulations on key sources of particulate pollution. However, increased heat, wildfire smoke and other emerging global drivers of urban aerosol pollution are now combining to create a new set of challenges for public health officials tasked with protecting millions of people on the East Coast. Research from Colorado State University published in npj Climate and Atmospheric Science begins to unpack and characterize these developing relationships against the backdrop of New York City. The research quantifies how existing particulate pollution from sources such as vehicle exhaust or consumer products are ...

Doctors and nurses are better than AI at triaging patients

2025-09-30
Vienna, Austria: Doctors and nurses are better at triaging patients in emergency departments than artificial intelligence (AI), according to research presented at the European Emergency Medicine Congress today (Tuesday) [1]. However, Dr Renata Jukneviciene, a postdoctoral researcher at Vilnius University, Lithuania, who presented the study, said that AI could be useful when used in conjunction with clinical staff, but should not be used as a stand-alone triage tool. “We conducted this study to address the growing issue of overcrowding in the emergency department and the escalating workload of nurses,” ...

Scientists solve mystery of loop current switching in kagome metals

2025-09-30
Quantum metals are metals where quantum effects—behaviors that normally only matter at atomic scales—become powerful enough to control the metal's macroscopic electrical properties.  Researchers in Japan have explained how electricity behaves in a special group of quantum metals called kagome metals. The study is the first to show how weak magnetic fields reverse tiny loop electrical currents inside these metals. This switching changes the material's macroscopic electrical properties and reverses which direction has easier electrical flow, a property ...

Reaction-induced restructuring of CoOx species to control selectivity in propane dehydrogenation

2025-09-30
Propene is one of the most important basic petrochemicals widely used for the production of polypropylene, solvents, acrylic acid, etc. The conventional routes for the manufacture of this building block include steam or fluid catalytic cracking of different oil fractions, methanol to olefin and non-oxidative propane dehydrogenation (PDH). The PDH approach has been attracting increasing attention because of the shale gas revolution. This reaction is carried out on a large scale using highly expensive or environmentally unfriendly Pt- or Cr-containing catalysts. Co-based catalysts are of particular interest due to their excellent ability to selectively activate C-H bonds in various alkanes.   It ...

Beneath the ice: spring sunlight triggers photoinhibition and recovery in lake Akan Marimo

2025-09-30
The marimo (Aegagropila brownii), a nationally designated Special Natural Monument of Japan, inhabits Lake Akan in Hokkaido, where environmental conditions fluctuate drastically with the seasons. Of particular concern is the period immediately after ice melt in early spring, when low water temperatures coincide with strong sunlight, posing a risk of severe damage to photosynthetic activity. In this study, a research team led by the Astrobiology Center conducted a detailed assessment of marimo photosynthetic performance during this critical transition period, combining field observations ...

12,000-year-old monumental camel rock art acted as ancient 'road signs' to desert water sources

2025-09-30
New findings highlight the pioneering role of human groups who lived in the interior of northern Arabia shortly after the hyper-arid conditions of the Last Glacial Maximum (LGM), guided by the return of seasonal water sources – and leaving behind a monumental legacy in rock art. A team of international archaeologists, led by the Heritage Commission, Saudi Ministry of Culture, and comprising scholars from the Max Planck Institute of Geoanthropology, KAUST (King Abdullah University of Science and Technology), University College ...

Home-delivered nutrition services for older adults under the Older Americans Act

2025-09-30
About The Study: The findings of this qualitative study of home-delivered nutrition services for older adults suggest that home-delivered meals programs achieved their intended outcomes and yielded meaningful benefits beyond their stated purpose that remain to be quantified. The findings also support funding the Older Americans Act Nutrition Program. Corresponding author: To contact the corresponding author, Kali S. Thomas, Ph.D., email kali.thomas@jhu.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/  (doi: 10.1001/jamanetworkopen.2025.34747) Editor’s Note: Please see the article ...

Electroacupuncture in patients with early urinary incontinence after radical prostatectomy

2025-09-30
About The Study: The findings of this randomized clinical trial show that electroacupuncture significantly accelerated postprostatectomy urinary continence recovery and may serve as a safe adjunct to standard care. These findings support integrating electroacupuncture into multimodal rehabilitation protocols to reduce early urinary incontinence burden. Corresponding author: To contact the corresponding author, Xuefeng Qiu, M.D., Ph.D., email xuefeng_qiu@nju.edu.cn. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi: 10.1001/jamanetworkopen.2025.34491) Editor’s Note: Please ...

Exercise can help to restore the immune system of people with post-COVID syndrome

2025-09-30
Exercise can help to restore a more normal, well-regulated immune system in people with post-COVID syndrome, according to a gold-standard randomised-controlled trial presented at the European Respiratory Society Congress in Amsterdam, the Netherlands [1]. The study was presented by Dr Enya Daynes, from a team of researchers led by Professor Nicolette Bishop from Loughborough University, UK. Dr Daynes told the Congress: “Research suggests that those with post-COVID syndrome are at an increased risk of immune dysregulation where, instead of protecting the body, the ...

Radiologists probe aftermath of mass casualty terror attack

2025-09-30
OAK BROOK, Ill. – Researchers in Israel have detailed the experience of one hospital’s radiology department during the mass casualty incident following the October 7, 2023, attack in southern Israel, to provide recommendations for future crisis preparedness, according to a new study published today in Radiology, a journal of the Radiological Society of North America (RSNA). The findings underscore the critical importance of in-hospital triage protocols, rapid staff mobilization and versatile imaging resources management. ...

Brain & Behavior Research Foundation awards 165 Young Investigator Grants to advance mental health research

2025-09-30
The Brain & Behavior Research Foundation (BBRF) today announced the 2025 class of 165 Young Investigator grantees, providing $11.4 million in two-year seed funding to early-career scientists pursuing innovative basic, translational, and clinical studies in brain and behavior disorders. This represents a 10% increase in the number of grants, to enhance our support for young scientists. Grantees were selected from 895 applications by BBRF’s Scientific Council, a volunteer body of 194 leading ...

Advanced AI tool detects tiny brain lesions in children with epilepsy

2025-09-30
An advanced AI tool can detect tiny brain lesions that cause severe epilepsy in children, allowing faster diagnosis, more precise treatment and a potential cure, according to a new study. Developed by a team at Murdoch Children’s Research Institute (MCRI) and The Royal Children’s Hospital (RCH), the ‘AI epilepsy detective’ can find lesions (focal cortical dysplasias) the size of a blueberry, in up to 94 per cent of cases with the support of medical imaging. MCRI’s Dr Emma Macdonald-Laurs, a RCH neurologist, who led the team that created the detector, said more accurate diagnosis of cortical dysplasia ...

Study finds altering one area of the brain could rid alcohol withdrawal symptoms

2025-09-30
By targeting a specific area of the brain, researchers at Washington State University may now hold the key to curbing the debilitating symptoms of alcohol withdrawal that push many people back to drinking. The new study found the answer to helping people get through alcohol withdrawal may lie in a region of the brain known as the cerebellum. In mice experiencing withdrawal, scientists were able to ease the physical and emotional symptoms by altering brain function in this brain region using both genetic tools and a specialized compound. The findings, published in the journal Neuropharmacology, could help pave the way for targeted therapies that make recovery more manageable. “Our ...

Firstborn behavioral problems impact sibling relationships

2025-09-30
BEER-SHEVA, ISRAEL, September 30, 2025 – A new study from Ben-Gurion University of the Negev (BGU) sheds light on how a firstborn child's behavior after the arrival of a sibling can predict the quality of their sibling relationship over time. The research, published in Social Development (https://doi.org/10.1111/sode.70008), highlights the crucial role of maternal reflective functioning in mitigating negative outcomes, particularly for children exhibiting internalizing behavioral problems. The study, co-authored by Prof. Naama Atzaba-Poria and Dr. Porat Yakov from BGU's Department ...

Study first to show if nesting heat affects sea turtle hatchling ‘IQ’

2025-09-30
As sand temperatures continue to rise, concerns about the future of sea turtles are growing. Hotter nests not only skew sex ratios – producing more females – but also reduce hatchling survival, slow growth, and increase the likelihood of physical deformities. Yet one important and often overlooked question remains: does this heat also affect cognitive ability – how well hatchlings can learn, adapt and respond to the rapidly changing world they face from the moment they emerge? A new study by researchers at Florida Atlantic University’s Charles E. Schmidt College of ...

Craig Newmark Philanthropies awards grant to CIAS Community Cybersecurity Clinic

2025-09-30
The Center for Infrastructure Assurance and Security (CIAS) at The University of Texas at San Antonio has received a $100,000 grant from Craig Newmark Philanthropies to support a pioneering program that provides low- and no-cost cybersecurity services to organizations in need while cultivating hands-on workforce development opportunities for UT San Antonio students. CIAS Community Cybersecurity Clinic (C4) strengthens community safety and resilience by offering organizations cybersecurity services, such as training, reputation ...

ESA's Gaia telescope discovers our galaxy’s great wave

2025-09-30
Our Milky Way galaxy never sits still: it rotates and wobbles. And now, data from the European Space Agency’s Gaia space telescope reveal that our galaxy also has a giant wave rippling outwards from its centre. We’ve known for about a hundred years that the galaxy’s stars rotate around its centre, and Gaia has measured their speeds and motions. Since the 1950s, we've known that the Milky Way's disc is warped. Then in 2020 Gaia discovered that this disc wobbles over time, similarly to the motion of a spinning top.   And now it has become clear that a great wave ...

Binghamton University named one of the nation’s best colleges by US News & World Report

2025-09-30
Binghamton University has been named one of the nation’s best universities and best values in the 2026 U.S. News & World Report rankings, recognized for its strong academic quality and affordability. The newly released list by U.S. News & World Report places Binghamton University as the #35 best college in the nation for value, up three spots from the 2025 list, and well above the 2024 list, when Binghamton was ranked #85 in that category. Looking at public universities specifically, Binghamton was ranked the #3 best value institution in the nation and the #1 best value ...

Machine learning sharpens earthquake risk assessment maps for Tokyo

2025-09-30
Tokyo, one of the world’s most densely populated megacities, sits on a highly active seismic zone where the threat of major earthquakes is ever-present. One of the most destructive aspects of seismic events in Tokyo is a geological phenomenon known as soil liquefaction. This occurs when the intense shaking from an earthquake causes saturated, loosely packed soil to temporarily lose its strength and stiffness, essentially causing the ground to behave like a liquid. The devastating effects of soil liquefaction have been documented many times, such as in the 1995 Great Hanshin-Awaji Earthquake, the 2011 Great East Japan Earthquake, and the recent 2024 Noto Peninsula ...

Pediatric investigation study links dietary preferences to childhood asthma in Shanghai

2025-09-30
Childhood asthma, a chronic inflammatory condition affecting millions worldwide, may be shaped not only by genetics and environment but also by what children prefer to eat. A new study published on 4 September 2025 in Pediatric Investigation has found that dietary preferences for pickled, smoked, and fried foods are linked to an elevated risk of asthma among first-grade children in Shanghai. Researchers surveyed 8,412 children aged about 6.6 years across 42 public schools in Minhang District, Shanghai. ...

Uncovering EUDAL – An RNA that shields oral cancer from drug therapy

2025-09-30
Oral cancer is one of the most common head and neck cancers worldwide, with hundreds of thousands of new cases diagnosed every year. Despite advances in surgery, radiotherapy, and chemotherapy, survival rates remain poor. One of the main challenges is that tumors quickly adapt and develop resistance to drugs that previously controlled them. A key factor behind this resistance is hypoxia—or the shortage of oxygen that develops inside tumors as they grow. Hypoxia not only promotes aggressive cancer behavior but also makes treatments less effective. Scientists have long suspected that hypoxia interacts with critical growth pathways in cancer cells, but ...

Inexpensive multifunctional composite paves the way to a circular economy

2025-09-30
Meeting global energy demands while mitigating environmental harm remains a major challenge, as many current solutions rely on expensive and toxic noble metals. In a recent study, researchers from Japan successfully developed a novel copper–cobalt oxide composite anchored on nitrogen-doped carbon nanostructures. Synthesized via a simple method, this material excels in energy storage, environmental remediation, and water splitting—offering a low-cost and sustainable alternative to conventional catalysts across multiple applications. The world is currently grappling ...

MIT joins giant Magellan telescope international consortium

2025-09-30
PASADENA, CA, and CAMBRIDGE, MA – September 30, 2025 – The Giant Magellan Telescope today announced that the Massachusetts Institute of Technology has joined its international consortium, constructing the $2.6 billion observatory in Chile. The Institute’s participation is enabled by a transformational gift to MIT from philanthropists Phillip (Terry) Ragon ’72 and Susan Ragon. “MIT is a world-renowned academic institution whose excellence in science, engineering, and discovery makes it a natural partner for us,” said Dr. Robert Shelton, President of the Giant Magellan Telescope. “MIT brings critical expertise ...
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