When we form a memory, brain cells need to deliver supplies to strengthen specific neural connections. A new study from MPFI and Weill Cornell Medicine has revealed how two cellular switches, Rab4 and Rab10, direct supplies to where they are needed.   Key Findings New tools track cellular supply routes: Scientists created biosensors to measure Rab proteins, cellular switches that direct the delivery of supplies inside cells. Beyond the findings in this paper, these sensors allow observation of the activity along complex supply routes, critical for many cellular functions. Rab4 provides a boost in the first minutes: During the strengthening of neuronal connections, ...

An innovative biotech startup founded by researchers at Washington University School of Medicine in St. Louis has been acquired by Lunit, a leading company in developing AI-based technologies for cancer prevention and early detection. The WashU startup, Prognosia, was created to develop software that harnesses AI to analyze mammograms and more accurately predict a woman’s five-year risk of developing breast cancer. The startup’s first software package, Prognosia Breast, received Breakthrough Device Designation from the Food and Drug Administration (FDA) earlier this year, ...

Researchers at NYU Abu Dhabi (NYUAD) have developed a new type of brain implant that can deliver drugs to multiple regions of the brain with high precision, offering fresh possibilities for the treatment of neurological disorders. The device, called SPIRAL (Strategic Precision Infusion for Regional Administration of Liquid), is a thin, flexible tube designed to release medication at several points inside the brain. This approach allows doctors and scientists to reach larger and more complex areas of brain tissue than current tools, while still keeping the implant small and minimally invasive. ...

Combining non-invasive brain stimulation and robotic rehabilitation improves motor recovery in mouse stroke model In your coverage, please use this URL to provide access to the freely available paper in PLOS Biology: https://plos.io/4gUkAy5    Article title: Combining gamma neuromodulation and robotic rehabilitation after a stroke restores parvalbumin interneuron dynamics and improves motor recovery in mice Author countries: Italy, Switzerland Funding: The study was funded by: Regione Toscana, PERSONA project, bando Salute 2018, https://www.regione.toscana.it/-/bando-ricerca-salute-2018, ...

The largest-ever study on neophobia, or fear of novelty, has discovered the key reasons why some bird species are more fearful of new things than others. Published in the journal PLOS Biology, the global multi-species study was led by Dr Rachael Miller while at Anglia Ruskin University (ARU) and the University of Cambridge – with ARU funding the publication of the research – alongside a core leadership team from the ManyBirds Project. Neophobia plays a crucial role in how animals balance risk and opportunity. While caution can protect individuals from potential threats, it can also limit their ability to adapt to new nesting sites, foods ...

October 14, 2025, Indianapolis, Indiana—Gene Brown, MD, RPh, became the President of the American Academy of Otolaryngology–Head and Neck Surgery and its Foundation (AAO-HNS/F) on October 14. He was elected by members of the AAO-HNS and will serve a one-year term leading the Academy's nearly 13,000 members who specialize in the treatment of the ears, nose, throat, and related structures of the head and neck. "Healthcare is changing rapidly and I'm honored to use this platform to keep our specialty’s focus on what matters most—supporting our members in their practices every day to ...

Irvine, Calif., Oct. 14, 2025 – Children living near the Salton Sea, in Southern California’s desert region of Imperial County, are experiencing poorer lung function than children exposed to less wind-blown dust, according to a new study led by researchers at the University of California, Irvine’s Joe C. Wen School of Population & Public Health. They found that higher dust exposure – measured in hours per year – was linked to lower lung function, with the negative effects most pronounced among children living closest to the lake. The work, published in the American Journal of Respiratory and Critical Care Medicine, marks one of the ...

About 100,000 of the estimated million people in the United States with multiple sclerosis (MS) have a progressive form of the disease, with symptoms that worsen continuously or after periods of remission. “Progressive MS is profoundly challenging because it is relentless and treatment options are limited,” said Francisco P. Gomez, a neurologist who specializes in MS and neuroimmunology. MS is believed to occur when the immune system attacks the myelin sheath — the protective coating of the nerve fibers that transmit ...

Indianapolis, Indiana – October 14, 2025 – The American Academy of Otolaryngology–Head and Neck Surgery Foundation (AAO-HNSF) 2025 Annual Meeting & OTO EXPO concluded its Scientific Oral Presentation program on Tuesday with 85 studies that establish new clinical correlations and provide evidence to optimize patient care across the full spectrum of otolaryngology practice. The final day's research program underscored the specialty's dedication to answering complex clinical questions ...

About The Study: This cohort study shows that high social adversity is associated with a high incidence of triple-negative breast cancer (TNBC) among Black women. As subtype is intrinsic to tumor development, these findings suggest an early and critical source of downstream breast cancer survival disparities. The findings of this study suggest potential social (epi)genomic and gene-environment interactions between social adversity and TNBC development in Black women. Corresponding author: To contact the corresponding author, Neha Goel, M.D., M.P.H., email goeln1@mskcc.org. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/  (doi: ...

About The Study: In this multicenter randomized clinical trial, rapid induction had higher retention than standard induction overall and in patients who tested positive for fentanyl through extended-release buprenorphine injection 2. Administration of injection 2 after 1 week was well tolerated and minimized time below target therapeutic levels of 2 ng/mL or greater compared with injection after 1 month. Corresponding author: To contact the corresponding author, Robert L. Dobbins, M.D., Ph.D., email robert.dobbins@indivior.com. To ...

Scientists have discovered a method to induce human endothelial cells from a small biopsy sample to multiply in the laboratory, producing more than enough cells to replace damaged blood vessels or nourish organs for transplantation, according to a preclinical study by Weill Cornell Medicine investigators. Endothelial cells form the inner lining of blood vessels and regulate blood flow, inflammation and healing. Traditional approaches for growing these cells in the lab have yielded only limited numbers before they lose their ability to function. The new method involves treating adult endothelial cells with a small molecule that triggers the hibernating cells to wake up and divide hundreds of ...

Hospice care aims to bring comfort, peace, and dignity to patients at the end of life. Yet for the growing number of Americans with dementia who enter hospice, their course is often long and unpredictable — making it especially important to ensure treatments align with each person’s goals and stage of illness. A new University of Michigan study published in JAMA Network Open finds that medications commonly prescribed to ease symptoms such as agitation, anxiety, and delirium — benzodiazepines ...

Researchers at Seoul National University have unveiled a groundbreaking thermal management technology capable of selectively implementing cooling and heating functions using a single material and process, without requiring electricity.   The technology developed by Professor Seung Hwan Ko's research team in the Department of Mechanical Engineering at SNU is drawing attention as an innovative solution that replaces existing complex processes. It enables the same transparent silicon polymer material to be processed into either a cooling or heating surface simply by adjusting ...

Seoul National University’s College of Engineering announced that a research team led by Professor Chul-Ho Lee from the Department of Electrical and Computer Engineering has outlined a comprehensive roadmap for the ‘gate stack’* engineering, a core technology for two-dimensional (2D) transistors, which are attracting attention as next-generation semiconductor devices. *Gate stack: A layered structure composed of dielectric and metal materials placed above the conductive channel in a transistor, used ...

In recent years, multiple global studies have consistently affirmed that early implementation and management is critical in reducing the risk of illness. Food and medicine homology (FMH) products are dual-functional substances that play both therapeutic and dietary roles. Integrating FMH products into daily life will become a critical strategy for the prevention of disease and the accomplishment of “the Healthy China Initiative”. However, at present, the development and current application of FMH products rely primarily on Western ...

One of Australia’s most devastating invasive predators took just 60 years to colonise the whole continent, according to new Curtin-led research that offers vital clues to help prevent future extinctions of native animals from foxes. Reconstructing the invasion patterns of foxes using new statistical simulation tools, the new paper has uncovered critical data needed to disentangle the role of foxes in the demise of Australia’s native animals. Lead author Dr Sean Tomlinson, from Curtin’s School of Molecular and Life Sciences, said researchers used hundreds ...

SAN ANTONIO — October 14, 2025 — Dr. Chris Thomas of Southwest Research Institute’s Mechanical Engineering Division has been named an Associate Fellow of the American Institute of Aeronautics and Astronautics (AIAA). AIAA Associate Fellows are recognized for overseeing important engineering or scientific work, outstanding contributions to their field, or original work of exceptional caliber. Associate Fellows must be recommended by at least three other associate fellows, be a senior member in good standing of the AIAA, and have a minimum of 12 years of professional experience. AIAA ...

The NCAA has awarded one of its four 2025 Graduate Student Research grants to support the dissertation research of doctoral student Jada Crocker (PhD in education candidate), who is exploring the academic advising experiences of Black/African American student-athletes at Minority Serving Institutions. As the lead researcher, Crocker is conducting in-depth interviews with participants to gain insights into the unique challenges and opportunities faced by these student-athletes at Division I institutions. This research aims to inform policy and practice by identifying ...

Aditya Johri, Professor, Information Sciences and Technology; Dr. Lawrence Cranberg Endowed Research Fellow, College of Engineering and Computing (CEC), received funding for the project: “Developing Artificial Intelligence Literacy Among Undergraduate Engineering and Technology Students Through Case-Based Instruction.”  This project aims to serve the national interest by improving undergraduate education to better prepare future engineering and computing professionals to use and develop artificial intelligence (AI).   The project's significance lies in its innovative use of situated case studies to help students ...

BOSTON, October 14, 2025 – Boston Children’s Hospital today announced that it has received a donation of $35 million from Hansjeorg Wyss, through the Wyss Medical Foundation. With this gift, Mr. Wyss builds on advancements made through a transformational gift in 2020 from his late wife, Rosamund Stone Zander. Because of Ms. Zander’s gift, the Center recruited experts in neurogenetics, medicinal chemistry and gene editing, and leveraged technology across seven cores, including human neuron, ...

(Auburn, AL) Imagine industrial processes that make materials or chemical compounds faster, cheaper, and with fewer steps than ever before. Imagine processing information  in your laptop in seconds instead of minutes or a supercomputer that learns and adapts as efficiently as the human brain. These possibilities all hinge on the same thing: how electrons interact in matter. A team of Auburn University scientists has now designed a new class of materials that gives scientists unprecedented control over these tiny particles. ...

WASHINGTON, Oct. 14, 2025 – More than a million people around the world rely on cochlear implants (CIs) to hear. CI effectiveness is generally evaluated through speech recognition tests, and despite how widespread they are, CI sound quality is typically not considered an indicator of users’ quality of life. In JASA Express Letters, published on behalf of the Acoustical Society of America by AIP Publishing, researchers from Vanderbilt University Medical Center and Ohio State University evaluated the relationships between sound quality, speech recognition, ...

WASHINGTON, Oct. 14, 2025 — For countless millions across the globe, commuting to work or school is an everyday routine. But during a pandemic, the practice can contribute enormously to the spread of infectious disease, a fact that many traditional metapopulation models often overlook because they are designed primarily for migration and treat people as if they rarely move locally. In Chaos, by AIP Publishing, a team of researchers from South Korea introduced a Commuter Metapopulation Model (CMPM) to address ...

The NHS incurs an estimated £340 million in additional healthcare costs annually due to weight-related health problems in children – but it is not just obesity driving the costs. New research from the University of Oxford reveals that underweight children need comparable medical support as those who are severely obese, challenging assumptions about childhood health priorities. The study, published in JAMA Network Open and funded by the National Institute for Health and Care Research (NIHR), provides the first national picture of healthcare costs linked to children’s weight, using NHS electronic health records from more than 268,000 children ...