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Changes in cardiovascular risk factors and health care expenditures among patients prescribed semaglutide

2025-08-08
About The Study: In this cohort study of adults prescribed semaglutide, initiation was associated with reductions in weight and cardiovascular risk factors but increases in health care expenditures, excluding semaglutide costs. These findings suggest potential clinical benefits in routine practice, while highlighting the need to evaluate the long-term impact of semaglutide on economic outcomes. Corresponding Authors: To contact the corresponding authors, email Jason Abaluck, PhD, (jason.abaluck@yale.edu) ...

Prescription drug utilization and spending by race, ethnicity, payer, health condition, and US state

2025-08-08
About The Study: In this cross-sectional study of 143 health conditions among persons in 50 states and Washington, DC, per capita pharmaceutical use was highest among white populations and lowest among Asian or Pacific Islander and Hispanic populations. However, after standardizing for age and disease prevalence (for 52 conditions with available data), prescription fills were substantially lower for Black populations relative to the all-population mean. These patterns varied by state, highlighting the need for local- and condition-specific ...

Mobile phone app reduced suicidal behavior among high-risk patients

2025-08-08
COLUMBUS, Ohio – A mobile phone app designed to deliver suicide-specific therapy reduced suicidal behavior among high-risk psychiatric inpatients, according to a new study by scientists at Yale School of Medicine and The Ohio State University Wexner Medical Center and College of Medicine. The study, published Aug. 8, 2025 in JAMA Network Open, found that the app, OTX-202, reduced the recurrence of post-discharge suicide attempts by 58.3% among patients who had previously attempted suicide. This reduction is a critical achievement for a group that is particularly vulnerable to repeated suicidal behaviors, the researchers said. Users of the app also experienced ...

SNU researchers develop wearable blood pressure monitor that attaches like a bandage for real-time continuous measurement

2025-08-08
Seoul National University College of Engineering announced that a research team led by Professor Seung Hwan Ko of the Wearable Soft Electronics Lab, Department of Mechanical Engineering, has developed a wearable electronic device that attaches to the skin like a bandage and enables real-time, continuous monitoring of blood pressure over extended periods.   Unlike conventional cuff-based blood pressure monitors that use an inflatable air bladder to apply pressure to the arm, this new technology continuously measures blood pressure with a compact, flexible electronic patch, garnering ...

How a rare cycad's wax crystals conjure blue without pigment

2025-08-08
The endangered South African cycad Encephalartos horridus may resemble a relic from the Jurassic age, but the species itself evolved long after dinosaurs disappeared. Still, it carries a biochemical legacy inherited from its distant ancestors—plants that once thrived alongside Jurassic fauna. A team led by Hiroshima University (HU) researchers found that its spiky, silvery-blue leaves owe their color not to pigment, but to a wax-based optical effect produced by a lipid compound that may date back to the dawn of land plants. In ...

Dana-Farber Cancer Institute unveils groundbreaking blood test for multiple myeloma

2025-08-08
Boston, MA — Researchers at Dana-Farber Cancer Institute have developed a blood test that could transform the diagnosis and monitoring of multiple myeloma (MM) and its precursor conditions. The new method, known as SWIFT-seq, utilizes single-cell sequencing to profile circulating tumor cells (CTCs) in the blood, offering a non-invasive alternative to traditional bone marrow biopsies. The study was published in Nature Cancer. “A lot of work has gone into the identification of genomic and transcriptomic features that predict worse outcome in MM, but we are still lacking the tests to measure them in our patients, said ...

Public data reveal extent of air quality impacts during 2025 Los Angeles wildfires

2025-08-08
In early 2025, wildfires spread in Los Angeles, destroying tens of thousands of homes and businesses. During the fires, smoke blanketed the region and online maps provided residents with rapid air quality information. Now, a study in ACS’ Environmental Science & Technology Letters compares the data that went into the maps from federal monitoring stations, low-cost sensors and satellites. Their results highlight the importance of combining multiple data sources to form easily accessible information for the public. “Timely and accurate air quality information is crucial for the public to ...

Towards better earthquake risk assessment with machine learning

2025-08-08
“A building is only as strong as its foundation” is a common adage to signify the importance of having a stable and solid base to build upon. The type and design of foundation are important for ensuring the structural safety of a building. Among several factors that can affect the design and laying of a foundation, bearing stratum depth, namely the depth at which the underlying layer of soil or rock has adequate strength to support a foundation, is one of the most crucial. This is because in regions that are prone to earthquakes or landslides, the bearing stratum depth, also ...

Reducing the global burden of liver cancer: Recommendations from The Lancet commission

2025-08-08
Liver cancer is the sixth most common cancer as well as the third highest cause of cancer-related mortality worldwide. In particular, a subtype of liver cancer known as hepatocellular carcinoma accounts for around 80% of all liver cancer cases. Given the increasing disease burden of hepatocellular carcinoma globally, a Commission consisting of experts in a wide range of fields – from clinical medicine to public health – has now been established to tackle this issue. Recently, in a comprehensive ...

Researchers succeed in building a low temperature hydrogen fuel cell, thanks to a scandium superhighway

2025-08-08
Fukuoka, Japan—As global energy demand increases, researchers, industries, governments, and stakeholders are working together to develop new ways of meeting that demand. This is especially important as we address the ongoing climate crisis and transition away from fossil fuels. One very promising type of energy generation is solid-oxide fuel cells, or SOFCs. Unlike batteries, which release stored chemical energy as electricity, fuel cells convert chemical fuel directly into electricity and continue to do so as long as fuel is provided. A common ...

New UC Irvine survey reveals shifting work landscape

2025-08-08
The University of California, Irvine School of Social Ecology today released the results of its latest UCI-OC Poll, shedding light on the changing nature of work in Orange County two years after the official end of the COVID-19 pandemic.   Conducted from June 20 to July 1, 2025, the survey of 800 Orange County adults offers insights into remote work preferences, attitudes toward artificial intelligence and overall job satisfaction – providing valuable insights for business leaders and policymakers navigating ...

Quantum ‘Starry Night’: Physicists capture elusive instability and exotic vortices

2025-08-08
Van Gogh’s “The Starry Night” has stirred the souls of art lovers for over a century. Now, its swirling skies may also speak to physicists, as it echoes the patterns of quantum turbulence. Physicists at Osaka Metropolitan University and the Korea Advanced Institute of Science and Technology have for the first time successfully observed the quantum Kelvin–Helmholtz instability (KHI) — a phenomenon predicted decades ago but never before seen in quantum fluids. The instability produces exotic vortex patterns known as eccentric fractional skyrmions, whose crescent-shaped structures ...

Excessive ultraprocessed foods (UPFs) and poor nutrition tied to poor health

2025-08-08
Science Advisory Highlights: Most ultraprocessed foods (UPFs) are characterized by poor nutritional quality, contributing to excessive calories, and are typically high in saturated fats, added sugars and sodium (salt), the combination of which is often abbreviated as HFSS, which contribute to adverse cardiometabolic health outcomes, including heart attack, stroke, obesity, inflammation, Type 2 diabetes and vascular complications. Observational studies have found links between eating higher amounts of UPFs and an increased risk of cardiovascular disease, chronic illness and mortality. Emerging evidence also suggests certain additives and industrial processing techniques ...

'One child called the robot "my little brother"': Can assistance tech become part of the family?

2025-08-08
What happens to a social robot after it retires?  Four years ago, we placed a small owl-shaped reading robot named Luka into 20 families’ homes. At the time, the children were preschoolers, just learning to read. Luka’s job was clear: scan the pages of physical picture books and read them aloud, helping children build early literacy skills.  That was in 2021. In 2025, we went back — not expecting to find much. The children had grown. The reading level was no longer age-appropriate. Surely, Luka’s work was done.  Instead, ...

Small but mighty: A biomimetic idea takes flight

2025-08-08
When Singapore celebrated its 50th  year of independence in 2015, a team of student researchers led by Associate Professor Foong Shaohui from Singapore University Technology and Design (SUTD) embarked on an ambitious challenge: to design and build a drone capable of 50 minutes of sustained flight. At the time, most hobbyist quadcopters could barely manage half of that. The SG50 Multi-Rotor Drone project succeeded, but to fly that long, the craft had to be large, complex, and heavy.   A decade on, Assoc Prof Foong has reached new heights in his drone research—this time by going small and pursuing a completely different ...

New hydrogel-based treatment accelerates infected wound healing and balances skin microbiota

2025-08-08
A novel ε-poly-L-lysine-loaded sodium-alginate/gelatin hydrogel (PSG15) has shown exceptional promise in accelerating the healing of infected wounds. This multifunctional injectable hydrogel delivers robust antibacterial properties while regulating macrophage polarization and stabilizing the skin microbiota. It significantly inhibited bacterial growth, including that of E. coli and S. aureus, and promoted tissue regeneration in infected wounds. In animal models, PSG15 enhanced angiogenesis, collagen deposition, and wound closure. These findings demonstrate the ...

New bioactive dressing promises faster diabetic wound healing

2025-08-08
Chronic diabetic wounds, including diabetic foot ulcers, are a significant burden for patients, as impaired blood vessel growth hinders the healing process. A recent breakthrough offers hope by combining small extracellular vesicles (sEVs) loaded with miR-221-3p and a GelMA hydrogel to target thrombospondin-1 (TSP-1), a protein that suppresses angiogenesis. This new bioactive wound dressing not only accelerates healing but also promotes blood vessel formation, offering a promising new approach to treating one of the most challenging complications of diabetes. Diabetic wounds, particularly foot ulcers, are notorious for their slow and often incomplete healing due to reduced blood flow and endothelial ...

Japan launches fully domestically produced quantum computer

2025-08-08
Osaka, Japan – A Japanese superconducting quantum computer, fully designed and built with homegrown components and software, went live on July 28th at The University of Osaka’s Center for Quantum Information and Quantum Biology (QIQB). This achievement signifies Japan's technological prowess in quantum computing, demonstrating the nation's capacity to design, manufacture, and integrate a complete quantum system. Visitors to Expo 2025, Osaka, Kansai, Japan will have the opportunity to interact with this cutting-edge technology through a dedicated exhibit. The project, spearheaded ...

Home is where the airfields are: What happens when hawks are moved from Los Angeles airports

2025-08-08
To a hawk an airport can look like the perfect place to settle down. The layout provides ample open space, perches, and nice habitat for a variety of prey species. However, congregations of birds, especially big birds, poses a safety issue for aircraft. A new study focused on Cooper’s Hawks (Accipiter cooperii), published in the Journal of Raptor Research, found that removing a hawk from an airfield and taking it somewhere else, called translocation, can serve as a method for reducing this risk. Researchers also showed that ...

Study: Sylvester researchers uncover molecular drivers of cellular differentiation

2025-08-08
MIAMI, FLORIDA (AUG. 7, 2025) – Researchers at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, have documented their use of a new RNA sequencing technology to uncover molecular drivers of cellular differentiation that could lead to better regenerative therapies. In addition to being used in the lab, the technique, Rapid Precision Run-On Sequencing (rPRO-seq), has the potential to help doctors understand patients’ disease states and response to treatment in real time. The findings appear ...

Withdrawal of kidney treatment significantly benefits patients and NHS

2025-08-07
Early withdrawal of a treatment for patients with a rare kidney disease is possible without relapse, safer for patients and saves the NHS millions of pounds, new research has revealed. Atypical Haemolytic Uraemic Syndrome (aHUS) is a life-threatening condition caused by an uncommon defect in the immune system which, in the past, led to kidney failure. Newcastle University worked with Newcastle Hospitals to carry out clinical trials into the pioneering drug, eculizumab, which led to the NHS approving the treatment from 2015, positively transforming the outlook for patients with the ...

Illinois Tech hosts EV Readiness Community Awards, showcasing nation-leading energy innovation

2025-08-07
CHICAGO—August 7, 2025—Illinois Institute of Technology (Illinois Tech) hosted the third annual EV Readiness Community Award Ceremony this week, celebrating 17 local governments across northern Illinois for their leadership in preparing for the transition to electric vehicles (EVs). The ceremony, co-led by ComEd and the Metropolitan Mayors Caucus, brought together mayors, municipal leaders, industry experts, and elected officials to recognize communities that have earned EV Ready designations through actionable local policy, planning, and infrastructure. The event featured remarks from Chicago Mayor Brandon Johnson, Senator Dick Durbin, ...

Rice bioscientist wins NSF CAREER Award to investigate bacterial toxins, expand inclusion in STEM

2025-08-07
When bacteria battle for survival, they do so with microscopic precision. Some produce toxins that target rival microbes, shaping not only their own fitness but the structure of entire microbial communities. Marcos de Moraes, assistant professor of biosciences at Rice University, is fascinated by these microbial skirmishes and how they might be harnessed for biotechnology. Now, with support from the National Science Foundation (NSF) Faculty Early Career Development Program (CAREER), de Moraes will study a little-understood family of bacterial toxins known as deaminases. The five-year, $1.2 million grant will fund research into the molecular ...

Study links exercise with decreased mortality and cardiovascular events in people recently diagnosed with type 2 diabetes but no previous cardiovascular disease

2025-08-07
New research to be presented at this year’s Annual Meeting of the European Association for the Study of Diabetes (EASD) in Vienna, Austria (15-19 September) shows, among people recently diagnosed with type with type 2 diabetes and no previous cardiovascular disease, a clear association exists between a person’s self-reported physical activity and their risk of all-cause mortality and major adverse cardiac events (MACE), that include heart attacks and strokes. The study is by Ms Line Eriksen and Dr Sidsel Domazet, Steno Diabetes Centre Odense, Odense University ...

Genetic testing reduces risks from chemotherapy for gastrointestinal cancer patients

2025-08-07
PHILADELPHIA— For some patients with gastrointestinal (GI) cancers like colorectal and pancreatic cancer, chemotherapy can cause severe, sometimes life-threatening side effects in those who carry certain genetic variants that can impact how their bodies process the drugs used to treat their disease. Testing for variants in two genes before starting chemotherapy can significantly improve patient safety by providing physicians with information to help tailor doses, according to new research from the Perelman School of Medicine at the University ...
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