A new algorithm called NTAC classifies neuron types using only synaptic connectivity data, outperforming traditional morphology-based methods and requiring just a fraction of labeled training data. The approach could reshape how we map the brain.

Recent technological advances facilitate the reconstruction of complete brain connectomes in small organisms and partial connectomes in mammals, involving the mapping of the network of neurons and synaptic connections. Accurate cell typing of these connectomes aids in interpreting circuit functions and comparing brain organization across species. Traditionally, cell typing relied on manual morphological classification by experts—a slow process that required detailed anatomical information. However, morphology can be deceptive or inadequate in many brain regions, especially in circuits ...

People often seem to understand language before they have actually heard enough words to determine its structure. In everyday conversation, listeners react immediately, anticipate what others will say, and rarely wait for a sentence to finish. This raises the question of how the brain is able to keep up with such rapid communication. In a new study, an international team of researchers, led by Associate Professor Chie Nakamura from the School of International Liberal Studies, Waseda University, Japan, investigated how listeners interpret structurally ambiguous sentences in ...

Percutaneous coronary intervention (PCI) is a standard treatment for significant coronary artery disease. Cardiologists use a catheter to place a stent that opens up the blockage and restores blood flow to the heart. However, dense, calcified atherosclerotic plaque can prevent proper placement or unfolding of stents, resulting in reduced blood flow to the heart even after PCI. Rotational atherectomy (RA) is a specialized technique used to modify heavily calcified plaque before stent placement. A conical burr ablates the calcified plaque, creating ...

Spinal cord injury (SCI) often leads to long-term loss of motor and sensory function, with limited available treatment options to restore the lost function. A major challenge in recovery is the formation of scar tissue at the injury site that prevents damaged nerve fibers from regenerating. Glial scarring has been thoroughly investigated, while fibrotic scar formation has been less studied. Transforming growth factor -β1 (TGF-β1), a signaling molecule that regulates inflammation and tissue repair, has been known to play a critical role in fibrosis in many tissues. Understanding how fibrotic scars form could aid in the ...

Cute, green, and sporting two sprigs of hair on his head, a mischievous baby dinosaur named Dooly is one of the most beloved cartoon characters in South Korea.   So, when researchers from The University of Texas at Austin and the Korean Dinosaur Research Center discovered a new species of baby dinosaur from Korea’s Aphae Island, they knew exactly what to call it: Doolysaurus. “Dooly is one of the very famous, iconic dinosaur characters in Korea. Every generation in Korea knows this character,” said ...

Stanford and CU Boulder researchers identified pTOS, a gut-bacteria metabolite that surges 1,000-fold in pythons after feeding. Given to obese mice, it cut appetite and drove 9% weight loss in 28 days through a mechanism entirely distinct from GLP-1 drugs.

Pythons don’t nibble. They chomp, squeeze and swallow their prey whole in a meal that can approach 100% of their body weight. But even as they slither stealthily around the forest, months or even a year may pass between massive mouthfuls. This pattern of extreme feasting and fasting taxes their metabolism far beyond what humans experience on a day-to-day basis. Now researchers at Stanford Medicine and the University of Colorado, Boulder, have found that a metabolite that spikes a thousandfold in pythons after a large meal causes obese laboratory mice to shun their food pellets and lose ...

According to a team of researchers at Baylor College of Medicine, Tongji University and collaborating institutions, weaning or switching from milk to solid food in early life doesn’t just change what babies eat, it helps reprogram the gut’s immune defenses to mount faster and stronger responses that can last into adulthood. The researchers report in Nature Microbiology that weaning reshaped the gut microbiome – the vast community of gut microorganisms – in mice, which in turn ‘trained’ intestinal stem cells to respond better to microbes later in life ...

LA JOLLA (March 19, 2026)—The United States and Mexico have been in a historic megadrought since the turn of the century. For more than 25 years, the American Southwest has faced the severe social and economic consequences of this megadrought—including a $1.1 billion agricultural loss in California in 2021 alone. With these conditions persisting, how can we help crops withstand drought while minimizing yield loss? Salk Institute scientists profiled nearly a million cells from the leaves of Arabidopsis thaliana, a small flowering plant that serves as a laboratory stand-in for important ...

University of Colorado Boulder researchers have discovered an appetite-suppressing compound in python blood that helps the snakes consume enormous meals and go months without eating yet remain metabolically healthy. The research, a collaboration with scientists at Stanford and Baylor universities, could inform new weight loss therapies that promote satiety without the nausea and muscle loss that can come with existing drugs. The findings appear in the journal Natural Metabolism on March 19. “This is ...

Barcelona, March 19, 2026 (EMBARGOED) -. Socioeconomic factors are widely recognized as potential modifiers of the relationship between air pollution and mortality, but the available evidence remains limited. In this context, a new study led by the Barcelona Institute for Global Health (ISGlobal), a centre supported by the ”la Caixa” Foundation, in collaboration with the Barcelona Supercomputing Center–Centro Nacional de Supercomputación (BSC-CNS), analysed how socioeconomic ...

University of Oxford press release UNDER EMBARGO UNTIL 19 March 2026 at 10:00 (London time), 19 March 2026 at 06:00 (US Eastern Time).. Burkitt lymphoma is an aggressive cancer affecting children in sub-Saharan Africa If treated early, over 90% survive but currently, slow diagnosis results in fewer than 50% of children surviving A new, highly accurate blood test has been shown to cut diagnosis time from 46.8 days (using current methods) to 6.5 days and increases detection rate from 40% to 93.3% This approach could help ensure that children with Burkitt lymphoma begin ...

Nearly a third of Americans over age 50 provide regular care to an adult relative or friend with a health issue or disability, a new poll finds. But many of them don’t know about, or use, local resources that could help them with caregiving. And about 20% of these caregivers are like highwire acrobats working without a net, the poll reveals. They’re taking care of someone else with health needs, but without close friends or family members to pitch in if they needed help with their own health concerns. The new findings from the University of Michigan National Poll on Healthy Aging could inform caregiver-related policy discussions at state and ...

Baby rattlesnake bites are less dangerous than bites from adult rattlesnakes, according to a new study from Loma Linda University that summarizes the origin, transmission, and prevalence of the longstanding myth that baby rattlesnake bites are more dangerous. The myth that baby rattlesnakes can’t control the release of their venom and therefore release it all when biting is refuted by the study. This incorrect belief has led “to negative consequences, including misinformed risk‐taking by those encountering snakes, unwarranted fear among snakebite victims, ...

Sudden drop in milk production, thickened milk, and cows under movment restrictions. Since 2024, American farmers have had bitter experiences with the feared bird flu (H5N1), which in several cases has been introduced to cattle – and then spread rapidly among cattle herds. In some instances, humans have been infected as well. The contagious virus is increasingly being transmitted from wild birds to mammals –such as cattle. The outbreaks in the U.S. raise the question of whether Denmark is sufficiently prepared should the infection spread to Danish cattle. But now there is good news for ...

What has long been interpreted as permanent and irreversible vascular damage may not be exclusively so. In people with Down syndrome—one of the most robust populations for studying Alzheimer’s disease due to the near-universal presence of the characteristic proteinopathies of this dementia from the age of 40—some lesions visible on magnetic resonance imaging do not follow a linear course. A longitudinal study from the Institut de Recerca Sant Pau (IR Sant Pau), published in Alzheimer’s & Dementia, shows that these alterations can fluctuate and even decrease over time in the Down syndrome population. This is especially true once the clinical symptoms ...

Researchers at Graz University of Technology (TU Graz) have developed a novel virtual reality (VR) system that could make the treatment of arachnophobia, also known as spider phobia, more targeted and personalised in the future. The “VRSpi” system is a prototype which analyses the EEG data and heart rate of the participants during a confrontation with spiders in a VR environment. Based on this objective measurement data, it adjusts the intensity of the stimuli in real time to the person’s current level of anxiety. This avoids over- or under-stimulation and optimises ...

Every time a tree trunk is sawn, it creates sawdust. Millions of tonnes of sawdust are produced every year worldwide, with most of it is burned to generate energy. This releases the carbon dioxide stored in the wood back into the atmosphere – which is not ideal from an environmental perspective. Now, a team of researchers at the Chair of Wood Materials Science at ETH Zurich and Empa has developed a process that can convert sawdust into a recyclable and environmentally friendly composite using the mineral struvite, a crystalline, colourless ammonium magnesium phosphate. This, in turn, keeps the sawdust in the material cycle for longer.  Struvite has ...

Thursday, 19 March 2026 – Today, the European Psychiatric Association (EPA) announces the move into full implementation of the 2026 Presidential Task Forces of its Action Plan, from protecting vulnerable groups to accelerating precision psychiatry, under President Professor Andrea Fiorillo. The Plan underpins the scientific sessions of the upcoming 34th European Congress of Psychiatry, held 28–31 March in Prague, marking the first congress of Professor Fiorillo’s presidency. The ...

A research team led by researchers at Chalmers University of Technology in Sweden, has, for the first time, successfully decoded leg movements directly from the remaining nerves in people with above-knee amputations. Using novel implantable neurotechnology and an AI method based on the nervous system’s own “language”, the researchers could do what was previously impossible and interpret detailed movements – even the will to wiggle toes. This technology opens the way to future leg prostheses that feel and act more like a natural part of the body. Helping amputees regain a functional and independent ...

Ludwig Kappos, MD, a leading physician-scientist at the University Hospital Basel in Basel, Switzerland has been awarded the 2026 John Dystel Prize for Multiple Sclerosis Research – one of the field’s highest honors. Dr. Kappos serves as director of the Research Center for Clinical Neuroimmunology and Neuroscience Basel and has played a central role in advancing MS research and treatment over the past several decades. Dr. Kappos will deliver the Dystel Prize lecture and formally receive the award at the ...

Powerful electronics don’t have to come at an environmental cost.  Scientists at Osaka Metropolitan University have developed high-performance, lead-free piezoelectric thin films directly on standard silicon wafers. Their results mark a significant step toward production of environmentally friendly energy-harvesting devices that are compatible with conventional semiconductor manufacturing.  Piezoelectric materials generate electric charge from mechanical stress and deform when exposed to an electric field. These materials are common, present for example in ...

A report drawing on input from 100+ UK water professionals finds that showering, toilet flushing, and leak reporting are the top behavior change targets - but the sector invests too little in understanding why people do these things the way they do.

Analyzing a decade of Japanese Pacific League data, researchers found that the designated hitter system does not change whether better teams win - it only changes how rosters are built. The finding arrives as Japan's Central League prepares to adopt the DH in 2027.