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E-scooter crashes mainly caused by reckless driving

E-scooter crashes mainly caused by reckless driving
2025-03-25
Crashes on electric scooters are mostly due to the behaviour of the riders, with one-handed steering and riding in a group being some of the largest risk factors. The researchers are also concerned about riders who deliberately crash or cause dangerous situations when riding, a phenomenon that seems to be specific to electric scooters. This is shown by a study from Chalmers University of Technology in Sweden, which for the first time examines the causes behind crashes with electric scooters from naturalistic data within an urban environment. The arrival of electric scooters in cities has meant an opportunity to quickly and smoothly make shorter trips. But not ...

Uncovering the brain’s flexible mechanisms for representing diverse numbers

Uncovering the brain’s flexible mechanisms for representing diverse numbers
2025-03-25
Abstract The National Institute of Information and Communications Technology (NICT, President: TOKUDA Hideyuki, Ph.D.) has revealed, through fMRI-based brain activity analysis, that multiple regions in the human cerebral cortex flexibly represent numerical quantity. This finding comes from research by HAYASHI Masamichi (Researcher (Tenure-Track)) at Center for Information and Neural Networks (CiNet), part of NICT’s Advanced ICT Research Institute, in collaboration with the University of Tokyo’s graduate student KIDO Teruaki (NICT ...

Biological pathway in the brain could help explain why teenage girls are more depressed than boys

2025-03-25
Depression is a mental health condition that affects 280 million people worldwide. It is twice as common in women than men and this pattern starts to develop during adolescence. Researchers have studied the biological processes that drive depression in adults and shown a potential role for the kynurenine pathway, but this is the first time it has been investigated in adolescents in relation to biological sex.  The study was published in Biological Psychiatry and funded by MQ Mental Health Research and supported by the National Institute for Health and Care Research (NIHR) Maudsley Biomedical Research Centre (BRC). The ‘kynurenine ...

Artisanal fishers are almost as accurate as satellites in producing environmental data

Artisanal fishers are almost as accurate as satellites in producing environmental data
2025-03-25
Artisanal fishers can be almost as accurate as satellite data when it comes to their awareness of features that can be found in the marine environment, a new study has shown. Published in the journal Ocean and Coastal Management, the research set out to establish the value of local ecological knowledge (LEK) and its ability to generate high quality habitat maps around five Greek islands in the eastern Aegean Sea. Ten fishermen, based on their individual experience and knowledge, were asked to pinpoint areas where they believed seagrass beds could be found along the coastlines of their respective islands. The maps they produced were then compared ...

Teaching kids about bugs benefits the environment

Teaching kids about bugs benefits the environment
2025-03-25
Pro-environmental behaviour increases among school students who participate in insect-related citizen science projects, according to new research from the University of Adelaide. Students who participated in citizen science project Insect Investigators, which engages students in the discovery of new insects, not only expressed an intention to change their personal behaviour but also to encourage others to protect nature. “As a result of their involvement in this program, students expressed intentions to further engage in insect–science–nature activities,” says the University of Adelaide’s Dr Erinn Fagan-Jeffries, who contributed ...

Tandem design on electrocatalysts and reactors for electrochemical CO2 reduction

Tandem design on electrocatalysts and reactors for electrochemical CO2 reduction
2025-03-25
Electrochemical CO2 reduction (ECR) driven by green electricity represents a promising strategy for CO2 mitigation and utilization by producing fuels and chemicals. Tandem strategy based on multifunctional tandem catalysts or cascade reactors enables deep CO2 reduction to high-value multi-carbon products. Nevertheless, it is challenging to precisely regulate the multi-step reaction pathways toward efficient CO2 conversion. A comprehensive understanding of the tandem reaction mechanisms is crucial for guiding the rational design of advanced catalysts and reactor systems to address these challenges. This review systematically ...

New study reveals impact of vermicomposted olive wastes on plant defense and pest control.

2025-03-25
A recent study published in Soil Ecology Letters has elucidated the combined effects of soil amendments and pest attacks on plant-induced defence mechanisms and their impact on the behaviour of biological control agents. The research, conducted by the Spanish National Research Council (CSIC) and Fundación MEDINA, focused on the utilisation of vermicomposted olive mill waste as a soil amendment and its consequence on the tri-trophic interactions between olive trees (Olea europaea), ...

An extension of process calculus for asynchronous communications between agents with epistemic states

An extension of process calculus for asynchronous communications between agents with epistemic states
2025-03-25
It plays a central role in intelligent agent systems to model agents’ epistemic states and their changes. Asynchrony plays a key role in distributed systems, in which the messages transmitted may not be received instantly by the agents. Epistemic interaction behaviors can change agents’ epistemic states, while the latter will affect the former. So far, the literature mainly focuses on formalizing the change of epistemic state after receiving information.  To model epistemic interactions between ...

Researchers achieve de novo biosynthesis of plant lignans using synthetic yeast consortia

2025-03-25
Lignans are low molecular weight polyphenolic compounds with important antitumor and antiviral properties. However, their low amounts in medicinal plants and complex structures make sustainable production through plant extraction and chemical synthesis challenging, limiting their availability to meet market demand. In a study published in Nature Chemical Biology, a research group led by Prof. ZHOU Yongjin from the Dalian Institute of Chemical Physics of the Chinese Academy of Sciences, collaborating with Prof. ZHANG Lei ...

Ferroptosis contributes to immunosuppression

Ferroptosis contributes to immunosuppression
2025-03-25
Iron-dependent ferroptosis, a non-apoptotic cell death mechanism, is gaining attention for its role in immune suppression. Ferroptosis, driven by excessive lipid peroxides and iron-dependent reactive oxygen species (ROS), differs from other cell death forms in its immunogenicity. It involves the regulation of the cystine/glutamate transport system xc−, with glutathione (GSH) and glutathione peroxidase 4 (GPX4) preventing toxic lipid peroxide accumulation. Ferroptosis-related factors are implicated in various diseases, including cancer and cardiovascular diseases. Macrophages, crucial for immune response, are affected by ferroptosis. ...

Study confirms accuracy of blood test for early Alzheimer’s detection in Asian populations

Study confirms accuracy of blood test for early Alzheimer’s detection in Asian populations
2025-03-25
A study in Alzheimer’s & Dementia, a leading journal in dementia research, has demonstrated the high accuracy of plasma p-tau217 as a blood-based biomarker for detecting abnormal brain beta-amyloid (Aβ) pathology, a hallmark of Alzheimer’s disease (AD). More significantly, the study validates its effectiveness even in individuals with cerebrovascular disease (CeVD), which is highly prevalent in Asian populations. This finding can enhance early diagnosis, improve patient risk stratification, and facilitate better clinical management of AD in diverse populations.   The ...

Cloud band movement influences wet spells during Indian monsoon

Cloud band movement influences wet spells during Indian monsoon
2025-03-25
The monsoon rains have long remained the lifeblood of India, providing the lion’s share of the water used for drinking and irrigation. The yearly arrival of the rains, which quenches the thirst of the harsh summers, is caused by the movement of cloud bands from the equator towards the north. A recent study from the Indian Institute of Science (IISc) has shown that contrary to previous understanding, the strength of the cloud band plays a key role in its movement as well as the density of rains that the Indian subcontinent receives during the wet spells of the monsoon. India receives 80% ...

Two USC innovators honored by the National Academy of Inventors for unlocking the power of the immune system

Two USC innovators honored by the National Academy of Inventors  for unlocking the power of the immune system
2025-03-25
Two researchers from the Keck School of Medicine of USC have been elected as senior members of the National Academy of Inventors (NAI), an organization that recognizes inventors holding US patents and promotes academic technology and innovation to benefit society.  The newly elected senior members are Preet Chaudhary, MD, PhD, professor of medicine and the Ronald H. Bloom Family Chair in Lymphoma Research, and Michael Selsted, MD, PhD, professor of pathology.  “Professors Chaudhary and Selsted are nationally known for their entrepreneurial research, and I’m thrilled to see them acknowledged with this ...

Increased use of chest x-rays linked to earlier lung cancer diagnosis and improved survival

2025-03-25
●      Records of more than 170,000 lung cancer patients combined with chest x-ray rates from 7,400 GP practices were analysed in the new research led by the University of Sheffield ●      The study, published in the British Journal of General Practice, shows link between the frequency of chest x-rays and earlier diagnosis and improved survival ●      Lung cancer is the leading cause of cancer deaths globally   A groundbreaking study has revealed a significant link between the frequency of chest x-ray referrals from GPs ...

From economic struggles to culture wars: New study reveals how GDP influences polarization around the globe

2025-03-25
Polarisation in lower-income countries largely flows from economic and material issues, while social topics and identity-related debates are the most polarising subjects in richer nations, new research reveals. The study from City St George’s, University of London analysed 40 years of global data to explore how modernisation influences ideological divides, shedding light on the factors driving ideological polarisation across different nations around the world. As political divisions deepen in many countries, the study clarifies the complex, multifaceted implications ...

NYU Abu Dhabi researchers develop affordable sensing system to restore sense of touch in minimally invasive surgery

NYU Abu Dhabi researchers develop affordable sensing system to restore sense of touch in minimally invasive surgery
2025-03-24
Abu Dhabi, UAE, March 24, 2025: Researchers from NYU Abu Dhabi’s Advanced Microfluidics and Microdevices Laboratory (AMMLab) have developed an innovative sensing system that restores the missing tactile feedback in minimally invasive surgery (MIS), enhancing precision, ease of use, and safety. The new "off-the-jaw" system integrates force and angle sensors into the handle of laparoscopic tools, providing surgeons with real-time measurements of grasping forces and insights into tissue stiffness and thickness. Minimally invasive surgery (MIS) involves small incisions, reducing ...

Rapid and accurate diagnosis of urinary tract infections using targeted next-generation sequencing: A multicenter comparative study with metagenomic sequencing and traditional culture methods

2025-03-24
BACKGROUND Urinary tract infections (UTIs) rank among the most prevalent bacterial infections globally. Traditional urine culture methods have significant limitations in detection time and sensitivity, prompting the need to evaluate targeted next-generation sequencing (tNGS) as a potential diagnostic tool. METHODS The study included a discovery cohort of 400 suspected UTI patients (202 analyzed) and a validation cohort of 200 patients (110 analyzed). The study assessed detection time, concordance rates, ability to identify polymicrobial infections, and antibiotic resistance genes (ARGs). Both clear and turbid ...

Black infants and children consistently have double the risk for death compared to Whites

2025-03-24
Embargoed for release until 5:00 p.m. ET on Monday 24 March 2025    Follow @Annalsofim on X, Facebook, Instagram, threads, and Linkedin         Below please find summaries of new articles that will be published in the next issue of Annals of Internal Medicine. The summaries are not intended to substitute for the full articles as a source of information. This information is under strict embargo and by taking it into possession, media representatives are committing to the terms of the embargo not only on their own behalf, but also on behalf of the ...

March/April Annals of Family Medicine Tip Sheet

2025-03-24
Original Research Family-Based Lifestyle Intervention Improves Weight Management and Cardiovascular Health Among High-Risk Patients Background and Goal: The PROgramme of Lifestyle Intervention in Families for Cardiovascular risk reduction (PROLIFIC) Study, conducted in India, aimed to assess whether a family-based approach to lifestyle interventions could improve weight management and obesity-related health outcomes among individuals with a family history of premature coronary heart disease​. Study Approach: In this cluster ...

Shared decision making among primary care clinic staff and family involvement improves follow-up for chronic patients

Shared decision making among primary care clinic staff and family involvement improves follow-up for chronic patients
2025-03-24
Original Research Background and Goal: Regular follow-up visits are critical for managing chronic conditions, yet some primary care clinics achieve higher visit regularity than others. This study aimed to identify specific strategies used by high-performing clinics to promote consistent follow-up visits for adults with chronic conditions​. Study Approach: This qualitative study used semi-structured interviews with 15 primary care physicians, 12 nurses, 15 administrative staff, and 4 pharmacists from 12 clinics—half with high temporal regularity (patients attending follow-ups consistently) and half with low temporal regularity, identifying strategies that helped high–temporal ...

Over half of patients prefer their own doctor and will wait longer for an appointment

Over half of patients prefer their own doctor and will wait longer for an appointment
2025-03-24
Original Research Background and Goal: This study focuses on how primary care patients balance the trade-off between continuity of care and access to timely appointments. It examines whether patients prefer to wait longer to see their own primary care physician (PCP) or prefer to see another clinician for faster care. Study Approach: Researchers analyzed data from a cross-sectional online survey of adult primary care patients in Michigan. Patients were presented with scenarios in the survey for different visit types—annual checkups, chronic and mental health follow-ups, ...

Newer hepatitis B vaccine shows promise as booster for health care workers

Newer hepatitis B vaccine shows promise as booster for health care workers
2025-03-24
Research Brief Background and Goal: Health care workers are at higher risk of hepatitis B infection due to occupational exposure to blood and body fluids. They are considered protected if they have a hepatitis B surface antigen antibody (anti-HBs) titer of  ≥10 mIU/mL after completing a full vaccination series. This study compared the effectiveness of Heplisav-B, a new hepatitis vaccine, vs. standard hepatitis B vaccines as a booster in previously vaccinated individuals. Study Approach: Researchers ...

Family-based lifestyle intervention improves weight management and cardiovascular health among high-risk patients

Family-based lifestyle intervention improves weight management and cardiovascular health among high-risk patients
2025-03-24
Original Research Family-Based Lifestyle Intervention Improves Weight Management and Cardiovascular Health Among High-Risk Patients Background and Goal: The PROgramme of Lifestyle Intervention in Families for Cardiovascular risk reduction (PROLIFIC) Study, conducted in India, aimed to assess whether a family-based approach to lifestyle interventions could improve weight management and obesity-related health outcomes among individuals with a family history of premature coronary heart disease​. Study ...

Long-term inhaled corticosteroid use for COPD linked to serious long-term health risks

2025-03-24
Background and Goal: Inhaled corticosteroids (ICS) are commonly prescribed for chronic obstructive pulmonary disease (COPD), but not recommended as first-line treatment unless patients have asthma/COPD overlap or frequent exacerbations. This study examined whether long-term ICS use (more than two years) increases the risk of serious health conditions compared with short-term use (less than 4 months). Study Approach: Researchers analyzed electronic health records from over 20 million patients, focusing on individuals aged 45 and ...

Ambulatory antibiotic use in France showed significant decline during the COVID-19 pandemic

2025-03-24
Research Brief Background and Goal: The COVID-19 pandemic and lockdown measures in France affected health care access and prescribing patterns, leading to significant changes in outpatient (ambulatory) antibiotic use. This study examined how systemic antibiotic use in France changed from 2020 to 2022 compared to expected trends. Study Approach: Researchers used nationwide health insurance data covering 67 million people to track monthly antibiotic prescriptions from January 2010 to March 2022. ...
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