Mount Sinai study finds antibody-producing immune cells can help shape cancer immunotherapy
2026-01-27
NEW YORK, (January 27, 2026) – Scientists at the Icahn School of Medicine at Mount Sinai have identified an important immune response that helps explain why some cancer patients benefit from immunotherapy while others do not.
In a study published in the January 27 online issue of Nature Medicine (DOI 10.1038/s41591-025-04177-6), the researchers found that antibody-producing immune cells called IgG1 plasma cells play a key role in helping patients respond to PD-1 immune checkpoint inhibitors.
PD-1 immune checkpoint inhibitors are a type ...
ACMG announces 2026 Medical Genetics Awareness Week celebrating professionals “making a difference together”
2026-01-27
The American College of Medical Genetics and Genomics (ACMG) announced today that the eighth annual Medical Genetics Awareness Week, sponsored by MyOme, will be held March 10–14, 2026, inviting the public, health professionals, patients, and policymakers to learn more about one of the most rapidly advancing and impactful fields in modern medicine.
Medical genetics plays a central role in today’s healthcare, guiding the diagnosis of rare diseases, informing cancer risk, shaping newborn screening, and enabling precision treatment ...
New research connects heart attacks to brain, nervous and immune systems
2026-01-27
Arteries become clogged. Blood flow is restricted and oxygen is cut off. The result is a heart attack, the world’s leading cause of death.
The conventional approach to studying and treating these episodes is to focus on the heart as an isolated organ. University of California San Diego research, led by the School of Biological Sciences, is upending the way heart attacks are viewed under a transformative new understanding of how cardiac events are interconnected with other systems.
In a study ...
Researchers advance understanding of female sexual anatomy to improve pelvic cancer radiotherapy
2026-01-27
NEW YORK, (January 27, 2026) – Researchers at the Icahn School of Medicine at Mount Sinai, in collaboration with other leading institutions across the country, have published an innovative study that provides radiation oncologists with practical guidance to identify and protect female sexual organs during pelvic cancer treatment.
Published in the latest issue of Practical Radiation Oncology, this study addresses a long-standing gap in cancer care by bringing key female sexual anatomy into consideration during routine radiotherapy ...
MLEDGE project proves federated learning can support real-world AI services
2026-01-27
After two and a half years of work, the MLEDGE project (Cloud and Edge Machine Learning), led by Professor Nikolaos Laoutaris at IMDEA Networks, has demonstrated that it is possible to combine federated learning with cloud and edge computing infrastructures to develop artificial intelligence solutions that are more secure, efficient, and closer to end users. The project’s results have been translated into real-world applications in both the traditional and digital economy.
Applications that make a difference
The project has developed and tested concrete applications that clearly illustrate its impact. First, real-time COVID ...
Lab-grown organoids reveal how glioblastoma outsmarts treatment
2026-01-27
UCLA scientists have developed advanced miniature 3D tumor organoid models that make it possible to study glioblastoma tumors in a setting that closely mirrors the human brain, shedding light on how the aggressive cancer interacts with surrounding brain cells and the immune system to become more invasive and resistant to therapy.
The organoid models, described in two complementary studies published in Cell Reports, are built from human stem cells and recreate the complex mix of cell types found in the human brain. This approach allows researchers to directly observe how patient-derived tumors communicate with healthy brain tissue, revealing ...
Insights from brain’s waste-flushing system may improve diagnosis of idiopathic intracranial hypertension
2026-01-27
A new study led by investigators from Mass General Brigham shows that a brain waste- “clean-up” system is influenced by intracranial pressure. The system, called the glymphatic system, was unrecognized until 2012 and helps circulate fluid and remove waste from the brain. Using magnetic resonance imaging (MRI), the research team found that changes in this fluid flow may help doctors better diagnose intracranial hypertension (IIH) less invasively and more reliably than with standard approaches currently ...
Tornado-forecast system can increase warning lead times, study finds
2026-01-27
LAWRENCE — Researchers at the University of Kansas have shown the National Severe Storms Laboratory’s Warn-on-Forecast System(WoFS) has potential to help weather forecasters issue warnings to emergency managers and the general public well before tornado formation. Their study appears in the peer-reviewed journal Weather and Forecasting.
The current lead time on issuing tornado warnings is about 15 minutes. The difference could save lives and property across the Great Plains (the classic ...
Dario Fiore receives ERC Proof of Concept to develop the VERIFHE Project
2026-01-27
Dario Fiore, research professor at IMDEA Software, has been awarded an ERC Proof of Concept (PoC) grant by the European Research Council. This funding scheme is designed to help translate high-level scientific results into applications with social and industrial impact and is exclusively available to researchers who have previously led ERC-funded projects.
The awarded project has a budget of €150,000 and a duration of 18 months, and will focus on one of the major challenges in digital technology today: ensuring both privacy and reliability in cloud-based machine learning services.
The project, ...
Broadband ultrasonic imaging shows defects in all types of concrete
2026-01-27
WASHINGTON, Jan. 27, 2026 — Concrete structures like roads and bridges require nondestructive testing methods to identify interior defects without destroying their structure. Most methods send sound waves into the material and capture the waves that echo back to create images of what’s inside and find defects. This process is similar to ultrasounds used to see inside the human body.
But unlike human tissues, concrete contains a diversity of materials, including stone, clay, chalk, slate, iron ore, and sand, that scatter sound waves and make clear imaging difficult to obtain.
In an article in Applied Physics ...
Discovery challenges long-held beliefs on early human technology in East Asia
2026-01-27
A newly excavated archaeological site in central China is reshaping long-held assumptions about early hominin behaviour in Eastern Asia.
Led by the Chinese Academy of Sciences, an international team of researchers conducted archaeological excavations at Xigou, located in the Danjiangkou Reservoir Region in central China, uncovering evidence of advanced stone tool technologies dating back 160,000-72,000 years ago.
The explorations, co-led by Griffith University, revealed hominins in this region were far more inventive and adaptable than previously believed, at a time when multiple large-brained ...
Medicaid expansion and overall mortality among women with breast cancer
2026-01-27
About The Study: The findings of this cohort study suggest that Medicaid expansion under the Affordable Care Act was associated with lower overall mortality among women ages 40 to 64 with breast cancer. Benefits were uneven, underscoring persistent racial and ethnic and socioeconomic disparities and the need for targeted interventions.
Corresponding Author: To contact the corresponding author, Chioma Ekwunazu, BS, email chioma.ekwunazu@bison.howard.edu.
To access the embargoed study: Visit ...
Acupuncture for migraine without aura and connection-based efficacy prediction
2026-01-27
About The Study: This trial demonstrated acupuncture’s efficacy for migraine without aura pain relief and functional improvement. Connectome-based predictive modeling identified default mode network and subcortical cerebellum hypoconnectivity as predicting pain relief and subcortical-cerebellum-motor hyperconnectivity as predicting reduced disability, providing a personalized treatment framework.
Corresponding Author: To contact the corresponding author, Lu Liu, PhD, email lululalavictor1985@126.com.
To ...
Liverpool scientists discover graphene’s electronic properties in 3D material in boost for green computing
2026-01-27
University of Liverpool researchers have discovered a way to host some of the most significant properties of graphene in a three‑dimensional (3D) material, potentially removing the hurdles for these properties to be used at scale in green computing.
Graphene is famous for being incredibly strong, lightweight, and an excellent conductor of electricity and its applications range from electronics to aerospace and medical technologies. However, its two-dimensional (2D) structure makes it mechanically fragile and limits its use in demanding environments and large-scale applications.
In a paper published today, a team of researchers have identified that 3D material, HfSn₂, ...
Xigou site discovery challenges long-held views on early human technology in East Asia
2026-01-27
An international research team has uncovered evidence of advanced stone tool technologies in East Asia dating back 160,000 to 72,000 years, with the findings recently published in Nature Communications.
Led by the Institute of Vertebrate Paleontology and Paleoanthropology (IVPP) of the Chinese Academy of Sciences, the team—which included researchers from China, Australia, Spain, and the United States—conducted multidisciplinary archaeological investigations at the Xigou site in the Danjiangkou Reservoir ...
Tiny gold spheres could improve solar energy harvesting
2026-01-27
Sunbeams contain a lot of energy. But current technology for harvesting solar power doesn’t capture as much as it could. Now, in ACS Applied Materials & Interfaces, researchers report that gold nanospheres, named supraballs, can absorb nearly all wavelengths in sunlight — including some that traditional photovoltaic materials miss. Applying a layer of supraballs onto a commercially available electricity converter demonstrated that the technology nearly doubled solar energy absorption compared to traditional materials.
Scientists are exploring materials that absorb light ...
A rich social environment is associated with better cognitive health outcomes for older adults, study finds
2026-01-27
Research by an interdisciplinary team from McGill University and Université Laval provides new insights into the links between social factors and cognitive health among aging adults.
While previous research had found positive correlations between specific measures of social connectedness and a variety of health outcomes, this study appears to have been the first to create profiles aggregating multiple social factors and to see how those correlated with cognitive health in older adults, the researchers said.
The team derived three social environment ...
Electroencephalography enables continuous decoding of hand motion angles in polar coordinates
2026-01-27
With the development of brain-computer interface (BCI) technology, the application of electroencephalography (EEG) signals in motion decoding has been expanding. Traditional BCI decoding is primarily based on Cartesian coordinates, which are suitable for representing linear movements but less efficient for decoding rotational or circular movements. In contrast, polar coordinates provide a more natural and compact representation for circular movements by directly encoding angular information, making it more efficient for decoding rotational ...
Call for pitches: Contribute to JMIR's News & Perspectives section
2026-01-27
(Toronto, January 27, 2026) JMIR Publications is seeking expert voices to contribute to our News and Perspectives section. We bridge the gap between academic rigor and scientific journalism, providing grounded, well-researched analysis that goes deeper than the headlines.
We invite journalists, scientific writers, researchers, clinicians, and digital health experts to pitch original content that informs, inspires, and empowers the health-tech community. Our aim is to build a digital health news service with global relevance, featuring voices, perspectives, ...
This flower evolved a new shape so that different birds could pollinate it. Then, it spread.
2026-01-27
Lipstick vines get their name from their bright red, tube-shaped flowers. But one member of this group of plants has lost its lipstick-like appearance— its flowers are shorter, wider, and yellowish green in color. It also attracts shorter-beaked birds than its crimson cousins do, and it’s found in different places. Scientists wanted to know how this plant evolved from its lipstick-like relatives. After observing birds visiting hundreds of plants and examining the plants’ DNA, the researchers found that the story of the green ...
Scientists engineer unsinkable metal tubes
2026-01-27
More than a century after the Titanic sank, engineers still have hopes of someday creating “unsinkable” ships. In a step toward reaching that lofty goal, researchers at the University of Rochester’s Institute of Optics have developed a new process that turns ordinary metal tubes unsinkable—meaning they will stay afloat no matter how long they are forced into water or how heavily they are damaged.
Chunlei Guo, a professor of optics and of physics and a senior scientist at URochester’s Laboratory ...
Used EVs currently offer car buyers lowest lifetime cost of ownership
2026-01-27
Now is a great time for anyone who's shopping for a used car to consider an electric vehicle, according to new research from the University of Michigan.
In assessing the lifetime ownership costs of used vehicles with different body styles and powertrains, the researchers found that completely electrified candidates offered the greatest savings.
For example, compared with a new midsized SUV with an internal combustion engine, a 3-year-old used EV version offered a lifetime savings of $13,000, according to the new study published in ...
Wild blueberries: New review explores benefits for heart, metabolism and the microbiome
2026-01-27
A new scientific review summarizes the growing body of research on wild blueberries and cardiometabolic health, which includes factors like blood vessel function, blood pressure, blood lipids (cholesterol and triglycerides) and blood sugar (glucose).
The review was published in Critical Reviews in Food Science and Nutrition and developed from an expert symposium hosted by the Wild Blueberry Association of North America (WBANA) in Bar Harbor, Maine.1 Twelve experts participated in the symposium from the fields ...
New white paper on rebuilding trust at work amid AI-driven change and burnout published by University of Phoenix College of Doctoral Studies
2026-01-27
University of Phoenix College of Doctoral Studies has published a new white paper, “Rebuilding the Social Contract,” by TaMika Fuller, DBA, an affiliate of the Center for Educational and Instructional Technology Research (CEITR), and Victoria Lender, DBA; both authors are College alumna. The paper examines how burnout, limited career development, and perceptions of low autonomy can erode trust at work—and what leaders can do to rebuild confidence, commitment and retention in an era shaped by accelerating technology and artificial intelligence.
Drawing on findings from the ...
How to motivate collective action on climate
2026-01-27
What does it take to spur individuals to act as a group with a shared purpose on climate change? According to a new Stanford-led study, the key is to show them how collective actions on climate have made a difference and often generate good vibes for participants.
A decade after nearly 200 world leaders agreed in Paris to limit climate change, solar power has become the fastest-growing source of new electricity and dozens of countries have cut emissions while growing their economies. Globally, emissions from burning fossil fuels – the largest contributor to human-caused climate change – ...
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