Reducing amounts of arsenic in drinking water can lower long-term deaths from cardiovascular disease and cancer, a new study shows. Researchers at NYU Langone Health, Columbia University, and the University of Chicago say their landmark analysis is important for public health because groundwater contamination from naturally occurring arsenic remains a serious issue worldwide. In the United States, more than 100 million people rely on potentially contaminated groundwater sources, especially private wells, for their drinking water. Arsenic is among the most common chemical pollutants. During the study, the drinking water and ...

About The Study: The findings of this study support an association between reduced arsenic exposure and improved health outcomes in populations exposed to contaminated drinking water. Corresponding Authors: To contact the corresponding authors, email Yu Chen, PhD, (Yu.Chen@nyulangone.org) and Habibul Ahsan, MD, (hahsan@bsd.uchicago.edu). To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jama.2025.19161) Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, ...

Fukuoka, Japan—In the ruthless world of parasitic ants, taking over a host colony is a matter of life and death. The conventional understanding has been that an invading queen must physically fight and kill the resident queen to seize control. However, a new study published in Current Biology details a more sinister strategy: a parasitic ant queen that chemically manipulates the host colony’s workers into executing their own mother. “The initial discovery was made by my friend Taku Shimada, the first author of the paper, who has been passionate about ants since childhood and runs a popular blog called ‘AntRoom.’ He observed the colony infiltration ...

About The Study: Approximately 1 in 30 trials and more than 74,000 trial participants were affected by grant funding disruptions. Affected trials disproportionately studied infectious diseases, prevention, and behavioral interventions, and were based in the Northeastern U.S. or in other countries. Because trials require sustained financial support to ensure operations and participant safety, unanticipated funding disruptions raise concerns about avoidable waste, data quality, and compromised ethical obligations to participants.  Corresponding Author: To contact the corresponding author, Anupam B. Jena, MD, PhD, email jena@hcp.med.harvard.edu. To ...

About The Study: In this cohort study of births in the United States from 2012 to 2021, the rate of overall cesarean births decreased slightly over the study period. However, racial and ethnic disparities persisted, with increasing risk of primary cesarean births among non-Hispanic Black individuals compared with individuals from other racial and ethnic groups. Quality improvement efforts to reduce unnecessary cesarean births should address this inequity and the structural racism that drives it.  Corresponding Author: To contact the corresponding author, Marie J. Boller, MD, email boller@ohsu.edu. To access the embargoed study: Visit our For The Media website ...

Constructing out-of-equilibrium molecular assemblies that deviate from thermodynamic equilibrium is a central challenge in materials science. While numerous studies have reported the creation of such states using external energy sources such as chemical fuels or light, few systems can adaptively access different states depending on how much energy is input. Developing such systems could offer new design principles for advanced functional materials capable of flexibly adapting to environmental changes, much like biological systems. In a recent study published online in Chem on November 17, 2025, researchers in Japan reported a supramolecular polymer system that can produce out-of-equilibrium ...

PHILADELPHIA—A rare glimpse into the brain activity of a patient with obesity and loss of control eating on tirzepatide, marketed as Mounjaro and Zepbound,  revealed that the medication suppresses signaling in the brain’s “reward center” thought to be involved in food noise – but only temporarily. Research suggests that the medication, a glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptor agonist, originally developed to manage Type 2 diabetes, may be able to treat a wide range of conditions ...

Do All Countries Benefit From Clinical Trials? A New Study Examines the Data A new study led by Yale’s Jennifer Miller, PhD, found that medicines are not physically accessible in many of the countries where they are tested for FDA approval. The findings were published in JAMA Internal Medicine.   For the study, researchers analyzed 172 FDA-approved medicines tested between 2015 and 2018 in nearly 90 countries. They found that five years after testing, only 24 percent of the medicines had received market authorization, or approval for distribution and patient access, in the countries where the clinical ...

The therapeutic landscape for hepatocellular carcinoma (HCC) has been revolutionized by the advent of molecular targeted therapies and immune checkpoint inhibitors (ICIs). While these systemic treatments have significantly improved outcomes for patients with intermediate and advanced HCC, their use is accompanied by a spectrum of adverse events, with drug-induced liver injury (DILI) being a common and potentially serious complication. To address this growing clinical challenge, the Chinese Society of Hepatology convened a multidisciplinary panel of experts to formulate the "Consensus on the Management of Liver Injury Associated with Targeted Drugs and Immune Checkpoint Inhibitors ...

In recent years, robots have increasingly become integral in enhancing human life, particularly with the growing demand for mobile robots with high payload-to-weight ratios and dynamic capabilities. Traditional wheeled or tracked robots are difficult to operate stably in complex real-world environments, which has driven research on legged robots. Legged robots leverage their distinctive “leg” structures to traverse obstacles and adapt to uneven terrain, demonstrating exceptional mobility when confronted with pronounced undulations or soft ground. ...

(Toronto, November 17, 2025) A new study published in the peer-reviewed journal JMIR Mental Health by JMIR Publications highlights a critical risk in the growing use of Large Language Models (LLMs) like GPT-4o by researchers: the frequent fabrication and inaccuracy of bibliographic citations. The findings underscore an urgent need for rigorous human verification and institutional safeguards to protect research integrity, particularly in specialized and less publicly known fields within mental health. Nearly 1 in 5 Citations Fabricated by GPT-4o in Literature Reviews The article, titled "Influence of Topic Familiarity and Prompt Specificity on Citation Fabrication in Mental ...

First tool to estimate percentiles of 30-year heart disease risk for adults ages 30–59 Aims to spark earlier prevention efforts amid rising diabetes and hypertension in young adults Men showed the highest long-term risk in national analysis Free online calculator is based on the American Heart Association’s PREVENT equations CHICAGO --- Just as saving for retirement starts early, so should protecting your heart. A new Northwestern Medicine study introduces a first-of-its-kind online calculator that uses percentiles to help younger adults forecast and understand their risk of a heart event over the next 30 years. ...

SAN ANTONIO — November 17, 2025 — Southwest Research Institute (SwRI) has significantly expanded its heat exchanger performance evaluation capabilities with a new facility designed to industry standards, the Large-Scale Heat Exchanger Test Facility (LS-HXTF) that supports testing up to five megawatts of heat loads as well as a wider range of thermal performance testing. Heat exchangers efficiently transfer heat between two or more fluids without mixing for a wide variety of heating and cooling applications. The ...

WILMINGTON, DEL. (November 14, 2025) – In a major step forward for cancer care, researchers at ChristianaCare’s Gene Editing Institute have shown that disabling the NRF2 gene with CRISPR technology can reverse chemotherapy resistance in lung cancer. The approach restores drug sensitivity and slows tumor growth. The findings appear today in the journal Molecular Therapy Oncology. This breakthrough stems from more than a decade of research by the Gene Editing Institute into the NRF2 gene, a known driver of treatment resistance. The results were consistent across multiple in vitro studies using human lung cancer cell lines and in vivo animal models. “We’ve ...

A University of Otago – Ōtākou Whakaihu Waka-led study has produced a detailed blueprint of a bacteriophage, furthering their potential in the fight against drug-resistant bacteria.   Lead author Dr James Hodgkinson-Bean, who completed his PhD in the Department of Microbiology and Immunology, says bacteriophages are “extremely exciting” in the scientific world as researchers search for antibiotic alternatives to combat the increasing risk of antimicrobial resistance.   “Bacteriophage viruses are non-harmful to all multi-cellular life and able to ...

Singapore, 17 November 2025—A new study by researchers from Duke-NUS Medical School has revealed that almost all community-dwelling older adults with advanced dementia in Singapore experience at least one potentially burdensome intervention in their last year of life. The findings highlight an urgent need for new strategies to support families and reduce unnecessary interventions at the end of life. Although the number of individuals living with dementia in the Asia-Pacific region is projected to rise to 71 million by ...

About a quarter of U.S. service members and veterans who start psychotherapy for post-traumatic stress disorder quit before they finish treatment. But not all therapies are equal in their appeal, with some effective approaches reporting the highest dropout rates, according to research published by the American Psychological Association. PTSD affects about 7% of veterans at some point in their lives, slightly higher than the rate seen in the general U.S. adult population, according to the U.S. Department of Veterans Affairs. Beyond PTSD’s emotional impact, the American Heart Association notes that it can also ...

New research examines how social approval from different sources predicts relationship quality for intercultural couples. Researchers found that having supportive friends can be a powerful protective factor, especially when they face disapproval from family or society more broadly. The research, published in Social Psychological and Personality Science, advances research on intercultural relationships by drawing on a large sample of people in such relationships. This sample allowed researchers to study how social approval varies across cultural backgrounds, racial pairing, relationship length, and gender. “The results highlight that friends and family can play distinct roles: for example, ...

Vision is one of the most fundamental senses, shaping how we perceive, navigate and interact with the world around us. Yet for more than 12 million Americans living with visual impairments, even small deficits can profoundly impact daily life, limiting independence and overall quality of life. Researchers have long recognized the potential of visual perceptual learning (VPL) – a process by which the brain improves its ability to detect subtle differences in visual stimuli, such as fine patterns or orientations – to enhance vision. VPL is already being explored ...

SEATTLE, WASH. — NOVEMBER 17, 2025 — Harnessing the muscle of one of the world’s fastest supercomputers, researchers have built one of the largest and most detailed biophysically realistic brain simulations of an animal ever. This virtual copy of a whole mouse cortex allows researchers to study the brain in a new way: simulating diseases like Alzheimer’s or epilepsy in the virtual world to watch in detail how damage spreads throughout neural networks or understanding cognition and consciousness. It simulates both form and function, with almost ten million neurons, 26 billion synapses, and 86 interconnected brain regions.   This spectacular achievement is the product ...

COLUMBUS, Ohio – A study using more than 27,000 sleep records of collegiate athletes provides the best evidence to date that early morning team practices take a toll on healthy sleep.   Researchers at The Ohio State University used data from wearable sleep trackers to measure sleep for 359 varsity athletes over five years.   They found that when male athletes had team practices that began before 8 a.m., they averaged about 30 minutes less sleep the night before when compared to later morning workouts. Female athletes averaged about 20 minutes less sleep.   Findings also showed evidence that ...

DALLAS, Nov. 17, 2025 — Hypertrophic cardiomyopathy (HCM) is the most common inherited heart disease and impacts an estimated 1 in 500 people in the U.S., according to the American Heart Association, a relentless force changing the future of health for everyone everywhere. Because many cases go undetected and untreated until acute symptoms occur, the Association is scaling up its efforts to improve diagnosis and treatment of HCM. HCM is a thickening of the lower main pumping chamber of the heart (the left ventricle). ...

World COPD Day: Short of Breath, Think COPD Appropriate diagnosis of COPD can have a very significant public health impact.  For Immediate Release In support of World COPD Day on November 19, the Global Initiative for Chronic Obstructive Lung Disease (GOLD), is drawing attention to the importance of correctly diagnosing COPD earlier - with the theme ‘Short of Breath, Think COPD’.   Chronic obstructive pulmonary disease (COPD) is a preventable and treatable condition marked by breathlessness, chronic sputum ...

Research overview A research team led by Associate Professor Tomoko Matsumoto from the Institute of Arts and Sciences at Tokyo University of Science, Japan, along with Associate Professor Daiki Kishishita and Associate Professor Atsushi Yamagishi, both from Hitotsubashi University, Japan, has demonstrated that providing people with information about the universal benefits of public goods significantly increases support for higher taxation. This finding reveals a new mechanism that could contribute to reducing inequality by expanding government size while maintaining tax progressivity. The ...

Fossil fuels release pollutants into the air when extracted and burned, but there’s more to their production than massive oil rigs diving deep into the Earth and smoky power plants. Those processes are examples of only the first and last—and generally most visible—moments in a fossil fuel’s five-stage journey.   Between the initial extraction site and the final power-generating facility, oil and gas are also refined to remove impurities, held in storage facilities, and transported from ...