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Social lives of viruses affect antiviral resistance

2025-12-05
Interactions among viruses can help them succeed inside their hosts or impart vulnerabilities that make them easier to treat. Scientists are learning the ways viruses mingle inside the cells they infect, as well as the consequences of their socializing.  Ph.D. student Alexander J. Robertson in the Molecular & Cellular Biology program at the University of Washington is among those scientists.  “I study the evolution of antimicrobial resistance through mechanisms which require interaction between microbes,” he explained. This week he is the lead author of a paper in Nature Ecology & Evolution on that topic. Polioviruses ...

Dose of psilocybin, dash of rabies point to treatment for depression

2025-12-05
ITHACA, N.Y. – An international collaboration led by Cornell University researchers used a combination of psilocybin and the rabies virus to map how – and where – the psychedelic compound rewires the connections in the brain. Specifically, they showed psilocybin weakens the cortico-cortical feedback loops that can lock people into negative thinking. Psilocybin also strengthens pathways to subcortical regions that turn sensory perceptions into action, essentially enhancing sensory-motor responses. The ...

Helping health care providers navigate social, political, and legal barriers to patient care

2025-12-05
In November, The Lancet, one of the world’s most esteemed medical journals, launched a new monthly series of case studies that goes beyond clinical diagnoses to illuminate the social and cultural forces that contribute to each patient’s condition.  Clinical case studies have long been a fixture in medical journals and are a primary way doctors and other health professionals continue learning after their initial training. Typically, case studies are short summaries of a patient’s predicament alongside a clinician’s assessment, diagnosis, ...

Barrow Neurological Institute, University of Calgary study urges “major change” to migraine treatment in Emergency Departments

2025-12-05
Barrow Neurological Institute, University of Calgary study urges “major change” to migraine treatment in Emergency Departments Advises that injectable treatments must be offered, reducing reliance on opioids  PHOENIX – A new study by Phoenix’s Barrow Neurological Institute and the University of Calgary has found which injectable treatments showed the most benefit for migraine patients and should be routinely offered by Emergency Departments (ED) when feasible. The findings from the study will update the guidelines for the American Headache Society.  Based on a systematic review of clinical trial data, the study ...

Using smartphones to improve disaster search and rescue

2025-12-05
HONOLULU, Dec. 5, 2025 — When a natural disaster strikes, time is of the essence if people are trapped under rubble. Conventional search-and-rescue methods use radar-based detection or employ acoustics that rely on sounds made by victims. Since most people carry their phones with them every day, Shogo Takada, a student at the University of Tokyo, is working on a way to use smartphone microphones to assist in locating disaster victims. Takada will present his results Friday, Dec. 5, at 11:45 a.m. HST as part of the Sixth Joint Meeting of the Acoustical Society of America and Acoustical Society of Japan, running Dec. 1-5 in Honolulu, ...

Robust new photocatalyst paves the way for cleaner hydrogen peroxide production and greener chemical manufacturing

2025-12-05
A new study highlights a promising path toward sustainable hydrogen peroxide production using sunlight, oxygen, and water, offering a cleaner alternative to the energy-intensive anthraquinone process that dominates global manufacturing today. In a commentary published in Sustainable Carbon Materials, researchers Bing Han of North China Electric Power University and Yin Zhang of Nanyang Technological University discuss a recent advancement in covalent organic framework technologies that could reshape photocatalytic chemical synthesis. The featured work, led by Yang and colleagues, demonstrates how a rational redesign of catalyst structures can dramatically boost the efficiency ...

Ultrafast material captures toxic PFAS at record speed and capacity

2025-12-05
Researchers have developed a new material that captures harmful PFAS chemicals from water in a matter of seconds, offering a promising pathway to address one of today’s most persistent environmental threats. The study reports that a nitrate-intercalated layered double hydroxide can remove perfluorooctanoic acid, a widely detected PFAS contaminant, with an exceptional capacity of 1,702 milligrams per gram. PFAS, often called forever chemicals because of their extreme persistence, are commonly found in drinking water, soils, and even human blood. Traditional adsorbents such as activated carbon and biochar often struggle with limited ...

Plant phenolic acids supercharge old antibiotics against multidrug resistant E. coli

2025-12-05
Plant derived phenolic acids can dramatically enhance the activity of existing antibiotics against multidrug resistant E. coli, offering a promising new tool in the global fight against antimicrobial resistance. In laboratory and insect models, these natural compounds helped an older antibiotic kill resistant bacteria more efficiently and reduced the chance that new resistance would emerge.​ “Instead of waiting many years and spending enormous resources to develop brand new antibiotics, we show that small molecules already present in plants can breathe new life into the drugs we rely on today,” ...

UNC-Chapel Hill study shows AI can dramatically speed up digitizing natural history collections

2025-12-05
A new study from UNC-Chapel Hill researchers shows that advanced artificial intelligence tools, specifically large language models (LLMs), can accurately determine the locations where plant specimens were originally collected, a process known as georeferencing. This task has traditionally been slow, expensive and dependent on significant manual effort. The team found that LLMs can complete this work with near-human accuracy while being significantly faster and more cost-effective.  “Our ...

OYE Therapeutics closes $5M convertible note round, advancing toward clinical development

2025-12-05
CROWN POINT, Ind. — OYE Therapeutics Inc., a privately held biopharmaceutical company developing first-in-class intravenous caffeine-based therapies for anesthesia recovery and opioid-induced respiratory depression, has announced the successful close of its $5 million convertible note financing, positioning the company to enter clinical development. The company is headquartered at the Purdue Technology Center of Northwest Indiana. CEO Brett Dines said the round drew strong new investor participation and was oversubscribed to $5.6 million, reflecting sustained confidence ...

Membrane ‘neighborhood’ helps transporter protein regulate cell signaling

2025-12-05
(MEMPHIS, Tenn. – December 5, 2025) When a cell receives a message from outside, it generates a molecule called cyclic AMP (cAMP) to relay this message. To ensure the signal reaches the correct effector without triggering pathways accidentally, cAMP levels must be maintained around their point of origin and at the right level. ABCC4, a protein that transports cAMP out of cells and also contributes to drug resistance, helps with this local control. Yet, how ABCC4 is held in place at the right spot to perform these functions was not clear. Scientists at St. Jude Children’s Research Hospital revealed that global elevation ...

Naval aviator turned NPS doctoral student earns national recognition for applied quantum research

2025-12-05
A Naval Postgraduate School (NPS) physics doctoral student has just been presented with a prestigious award for his pioneering research in quantum sensing using a unique atomic fountain. U.S. Navy Cmdr. Jens Berdahl, a former naval aviator and F/A-18 pilot currently pursuing his doctorate through the service’s Permanent Military Professor (PMP) program, was recently presented with the highly competitive Margaret Burbidge Award for Best Experimental Research by a Graduate Student.  Presented by the American Physical Society, Far West Section, Berdahl received the award while presenting his research on NPS’s ...

Astronomers watch stars explode in real time through new images

2025-12-05
Astronomers have captured unprecedented, detailed images of two stellar explosions—known as novae—within days of their eruption. The breakthrough provides direct evidence that these explosions are more complex than previously thought, with multiple outflows of material and, in some cases, dramatic delays in the ejection process. The international study, published in Nature Astronomy, used a cutting-edge technique called interferometry at the Center for High Angular Resolution Astronomy, or CHARA, Array in California. This approach allowed scientists, including Michigan State University researcher Laura Chomiuk, to combine the light from multiple ...

Carbon-negative building material developed at Worcester Polytechnic Institute published in matter

2025-12-05
Worcester Polytechnic Institute (WPI) researchers have created a new carbon-negative building material that could transform sustainable construction. The breakthrough, published in the high-impact journal Matter, details the development of enzymatic structural material (ESM), a strong, durable, and recyclable construction material produced through a low-energy, bioinspired process. Led by Nima Rahbar, the Ralph H. White Family Distinguished Professor and head of the Department of Civil, Environmental, and Architectural Engineering, the research team engineered ESM by using an enzyme that helps convert carbon dioxide into solid mineral particles. ...

Free radicals caught in the act with slow spectroscopy

2025-12-05
Why does plastic turn brittle and paint fade when exposed to the sun for long periods? Scientists have long known that such organic photodegradation occurs due to the sun’s energy generating free radicals: molecules that have lost an electron to sunlight-induced ionization and have been left with an unpaired one, making them very eager to react with other molecules in the environment. However, the exact mechanisms for how and why the energy from the sun’s photons get stored and released in the materials over very long ...

New research highlights Syntax Bio’s platform for simple yet powerful programming of human stem cells

2025-12-05
***Under strict embargo until 14:00 (2:00 pm) U.S. Eastern Time Friday, 05 December 2025 *** FOR IMMEDIATE RELEASE  New Research Highlights Syntax Bio’s Platform for Simple Yet Powerful Programming of Human Stem Cells The Science Advances publication details Cellgorithm™, a CRISPR-based technology that gives researchers greater control over gene activity and sets the stage for future applications in stem cell programming for research and therapeutic development. CHICAGO, Dec. 8, 2025 – Syntax Bio, a synthetic biology company programming the next generation of cell therapies, today announced the publication of new research in Science Advances detailing ...

Researchers from the HSE University investigated reading in adolescents

2025-12-05
Psycholinguists from the Center for Language and Brain found that phonological processing skills continue to influence text reading fluency in 15-to-18-year-old adolescents. This finding argues the long-held belief that in this age group the phonological processing skills are not involved in reading. The study was published in PLOS One.   Phoneme – is the smallest phonetic unit that helps to distinguish one word from another. Previously, it was stated that phonological processing skills (i.e., the ability to operate with phonemes) are required for early stages of reading development. However, researchers from the Center for Language and ...

Penn Nursing study: Virtual nursing programs in hospitals fall short of expectations

2025-12-05
Hospitals struggling to attract and retain enough registered nurses at the bedside are implementing alternative strategies to ensure patients get needed nursing care. This includes virtual nursing programs, a model of care in which nurses use video and messaging technologies to assess, monitor, educate, and coordinate care for hospitalized patients from an off-site location. A new study from the Penn Nursing’s Center for Health Outcomes and Policy Research (CHOPR)—published in JAMA Network Open today—surveyed 880 in-hospital nurses about their experiences working alongside ...

Although public overwhelmingly supports hepatitis B vaccine for a newborn, partisan differences exist

2025-12-05
On December 5, 2025, the Trump administration’s Advisory Committee on Immunization Practices (ACIP), whose members were handpicked by Health and Human Services (HHS) Secretary and vaccination critic Robert F. Kennedy Jr., is scheduled to determine whether it should recommend that the Centers for Disease Control and Prevention (CDC) change the recommendation in place since 1991 that newborns be vaccinated against hepatitis B. Infection with hepatitis B can cause liver damage (cirrhosis), liver cancer, and even death. Kennedy fired the members of ACIP ...

DFW backs UTA research to bolster flood resilience

2025-12-05
The University of Texas at Arlington and Dallas Fort Worth International Airport are expanding a multi-year partnership to improve stormwater management, environmental protection and long-term operational resilience at one of the world’s busiest airports. After completing the first phase of the project, DFW has extended its partnership with UTA’s Water Engineering Research Center (WERC) with a $2.38 million investment to build on its previous work by shifting from assessment to solutions. In total, DFW has committed more than $4 million to UTA under the interlocal agreement ...

AI brain scan model identifies stroke, brain tumors and aneurysms – helping radiologists triage and speed up diagnoses

2025-12-05
A new AI model could help radiologists identify brain abnormalities in MRI scans for all conditions including stroke, multiple sclerosis and brain tumours. The study, led by researchers at King’s College London and published in Radiology AI, shows how AI could address the growing backlogs due to radiologist shortages as well as an increasing demand for MRIs year on year for over a decade. These backlogs could result in treatment delays and poorer patient outcomes because MRI scans are vital for diagnosing and monitoring a range of brain conditions ...

U.S. News & World Report gives Hebrew Rehabilitation Center highest rating

2025-12-05
Hebrew Rehabilitation Center’s skilled nursing units have been rated as high-performing and recognized among the Best Nursing Homes of 2026 by U.S. News & World Report. This year, the Rehabilitative Services Units at Hebrew Rehabilitation Center in Boston and the Hebrew Rehabilitation Center at NewBridge on the Charles in Dedham, MA, were each rated as high-performing, the highest designation available. “We are pleased to receive this recognition from U.S. News & World Report for the quality efforts of the multidisciplinary teams serving our Rehabilitative ...

Optica and DPG name Antoine Browaeys 2026 Herbert Walther Award recipient

2025-12-05
WASHINGTON — A pioneer in the field of quantum, Antoine Browaeys, Institut d'Optique, CNRS, France, has been recognized by Optica, Advancing Optics and Photonics Worldwide, and the Deutsche Physikalische Gesell­schaft (DPG) with the 2026 Herbert Walther Award. He is honored for the realization of arrays of single neutral atoms held in optical tweezers as a platform for exquisitely controlled quantum simulation of many-body physics, and their development as a candidate platform for scalable quantum computation. “Congratulations to Antoine Browaeys on this well-deserved recognition,” said Jim Kafka, Optica 2025 President. “He is a world-leader ...

The presence of a gun in the home increases the risk of suicide by three to five times

2025-12-05
In addition to posing physical and life risks, access to firearms has an impact on mental health. It increases suicides, intensifies psychological fragility, and amplifies violence. This is the conclusion of a study published in the September issue of the scientific journal Harvard Review of Psychiatry. The study was led by researchers from the Institute of Psychiatry at the University of São Paulo’s Medical School (FM-USP) in Brazil. The researchers conducted a systematic review of 467 studies from various ...

PFAS exposure and endocrine disruption among women

2025-12-05
About The Study: Data from this cross-sectional study show that exposure to single and mixtures of perfluoroalkyl and polyfluoroalkyl substances (PFAS) was associated with higher odds of endocrine disruption (ED) among women. The findings demonstrated that certain PFAS compounds, particularly n-PFOS, were associated with ED. PFAS are widely used in industry, and increasing evidence suggests that even low-level, chronic exposure may disrupt endocrine function and harm health. Exposure to mixtures of PFAS remained positively associated with developing ED.  Corresponding Author: To contact the corresponding author, Rezaul Karim Ripon, ...
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