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Endocrine Society names Andrews as new Editor-in-Chief of Endocrinology

2024-04-25
WASHINGTON—The Endocrine Society has appointed Zane B. Andrews, Ph.D., of Monash University in Melbourne, Australia, as Editor-in-Chief of its flagship basic science journal, Endocrinology. Andrews has been Deputy Editor of the journal since 2020 and will be taking on this role as previous Editor-in-Chief Carol Lange, Ph.D., of the University of Minnesota in Minneapolis, Minn., transitions into her new position as the Society’s President-Elect. “I am thrilled that Dr. Andrews is taking on this opportunity to lead Endocrinology. He has already provided immense value as the Deputy Editor. I very recently met with ...

Type of surgery and its risk level has significant impact on complications and death in elderly patients

2024-04-25
Key Takeaways  Frailty and procedure risk are both associated with increased postoperative complications and odds of death. However, certain patients are at increased risk of postoperative complications and death in comparison to the same patients who are assessed solely on their level of frailty.   Compared to frailty alone, procedure risk had a stronger association with adverse outcomes among elderly patients undergoing emergency surgery. For example, high-risk procedures resulted in an 8-fold increase in the odds of death following surgery, ...

National Center to Reframe Aging teams up with Longevity Ready Maryland Initiative

2024-04-25
The National Center to Reframe Aging — the leading organization for proven communication strategies and tools to effectively frame aging issues — is partnering with the Maryland Department of Aging in development of its multisector plan on aging, the Longevity Ready Maryland Initiative. The National Center will be a strategic partner providing guidance in Maryland’s statewide campaign to advance an equitable and complete story about aging and promote proven communication strategies to frame aging issues. Key leaders and staff of the Maryland Department of Aging will participate in educational opportunities and receive resources to consistently apply ...

Study reveals racial disparities in COVID-19 testing delays among healthcare workers

2024-04-25
At the height of the pandemic, timely access to COVID-19 testing was crucial for curbing the spread of the disease and informing treatment decisions. Studies have unveiled racial and ethnic disparities in COVID-19 infection rates, clinical outcomes, and access to treatment and testing. However, until now, there has been a gap in research specifically examining the connection between race, ethnicity, and delayed COVID-19 testing amongst health care personnel. Researchers from Brigham and Women’s Hospital, a founding member ...

Estimating emissions potential of decommissioned gas wells from shale samples

Estimating emissions potential of decommissioned gas wells from shale samples
2024-04-25
UNIVERSITY PARK, Pa. — Extracting natural gas from shale formations can provide an abundant, lower-carbon footprint fossil fuel, but also creates concerns over increased methane emissions. A team led by Penn State researchers has developed a new tool that can estimate the emission potential of shale wells after they are no longer active. The findings, published in the journal Science of the Total Environment, revealed that methane begins diffusing from the shale formation after a well is decommissioned  and that this represents a notable source of methane ...

Nanomaterial that mimics proteins could be basis for new neurodegenerative disease treatments

Nanomaterial that mimics proteins could be basis for new neurodegenerative disease treatments
2024-04-25
MADISON — A newly developed nanomaterial that mimics the behavior of proteins could be an effective tool for treating Alzheimer's and other neurodegenerative diseases. The nanomaterial alters the interaction between two key proteins in brain cells — with a potentially powerful therapeutic effect. The innovative findings, recently published in the journal Advanced Materials, were made possible thanks to a collaboration between University of Wisconsin–Madison scientists and nanomaterial engineers at Northwestern ...

ASC scientists released long-term data of ground solar-induced fluorescence to improve understanding of canopy-level photosynthesis

ASC scientists released long-term data of ground solar-induced fluorescence  to improve understanding of canopy-level photosynthesis
2024-04-25
In recent years, the scientific community has increasingly turned its attention to sustainable agriculture, aiming to maximize crop yield while minimizing environmental impact. A crucial aspect of this research involves understanding the fundamental processes of plant photosynthesis and how they can be monitored at scale. One promising method for assessing photosynthetic activity is through the measurement of sun-induced chlorophyll fluorescence, a byproduct of photosynthesis that can be detected ...

Study uncovers drug target in a protein complex required for activation of NF-κB, a transcription factor involved in multiple diseases

2024-04-25
RESEARCH SUMMARY   Study Title:  Positive selection CRISPR screens reveal a druggable pocket in an oligosaccharyltransferase required for inflammatory signaling to NF-κB   Publication:  Cell (4/25/24)   Dana-Farber Cancer Institute authors include: William Kaelin, Jr, MD, senior author; Benjamin Lampson, MD, PhD, first author; Lixia He, PhD; Jamie Pfaff, MD; Nitin Shirole, PhD; and Yanfeng He, PhD   Summary: A new paper by Dana-Farber Cancer Institute ...

The longer spilled oil lingers in freshwater, the more persistent compounds it produces

2024-04-25
Oil is an important natural resource for many industries, but it can lead to serious environmental damage when accidentally spilled. While large oil spills are highly publicized, every year there are many smaller-scale spills into lakes, rivers and oceans. And, according to research published in ACS’ Energy & Fuels, the longer that oil remains in freshwater, the more chemical changes it undergoes, creating products that can persist in the environment. Approximately 600,000 gallons of oil were accidentally spilled into the environment ...

Keck Medicine of USC opens new Las Vegas transplant care clinic

Keck Medicine of USC opens new Las Vegas transplant care clinic
2024-04-25
LOS ANGELES — More than 660 Nevadans need an organ transplant, according to Nevada Organ Network, a federally designated organ procurement organization; but many currently struggle to access care because of limited transplant services available in Nevada.   Amid the growing need for additional transplant services in the state, Keck Medicine of USC has opened a new location in Las Vegas that will provide specialized care for patients in Las Vegas and surrounding communities who need a liver or heart transplant.   The clinic is the first in Nevada to offer ...

How immune cells communicate to fight viruses

How immune cells communicate to fight viruses
2024-04-25
Chemokines are signalling proteins that orchestrate the interaction of immune cells against pathogens and tumours. To understand this complex network, various techniques have been developed to identify chemokine-producing cells. However, it has not yet been possible to determine which cells react to these chemokines. Researchers at the University Hospital Bonn (UKB) and the University of Bonn have developed a new class of genetically modified mice that enables the simultaneous identification of chemokine producers and sensors. Using the chemokine ...

Unveiling the lionfish invasion in the Mediterranean Sea

Unveiling the lionfish invasion in the Mediterranean Sea
2024-04-25
Researchers from Wageningen University and Research, the Netherlands, have published a comprehensive study on the invasion of lionfish in the Mediterranean Sea, highlighting a rapid spread and the potential ecological impacts. Published in the open-access journal NeoBiota, the research shows the lionfish species Pterois miles has significantly expanded its territory in the Mediterranean since the invasion began around ten years ago. The invasive species has established presence in the eastern Mediterranean, with observations now extending to colder waters previously ...

Scientists regenerate neural pathways in mice with cells from rats

2024-04-25
Two independent research teams have successfully regenerated mouse brain circuits in mice using neurons grown from rat stem cells. Both studies, published April 25 in the journal Cell, offer valuable insights into how brain tissue forms and present new opportunities for restoring lost brain function due to disease and aging. “This research helps to show the brain’s potential flexibility in using synthetic neural circuits to restore brain functions,” says Kristin Baldwin (@kkbaldwin238), a professor at Columbia University in New York and corresponding author ...

Publicly funded fertility program linked to a decrease in rate of multifetal pregnancy

2024-04-25
Kingston, ON, March 27, 2024 – In the era after the introduction of publicly funded in vitro fertilization (IVF) mandating elective single embryo transfer, the multifetal pregnancy rate decreased significantly for IVF, but the contribution of ovulation induction and intrauterine insemination (OI/IUI) to multifetal pregnancy still needs attention, according to a new study from ICES and Queen’s University.  Twins, triplets, and higher multifetal pregnancies are associated with some adverse outcomes ...

Cancer survivors reporting loneliness experience higher mortality risk, new study shows

Cancer survivors reporting loneliness experience higher mortality risk, new study shows
2024-04-25
A new study led by researchers at the American Cancer Society (ACS) showed people surviving cancer who reported feeling more lonely experienced a higher mortality risk compared to survivors reporting low or no loneliness. Researchers observed the highest mortality risk among the group reporting the highest levels of loneliness, even after adjusting for sociodemographic characteristics. The findings are published today in the Journal of the National Comprehensive Cancer Network (JNCCN). “Loneliness, ...

Psychiatric symptoms, treatment uptake, and barriers to mental health care among US adults with post–COVID-19 condition

2024-04-25
About The Study: In this nationally representative cross-sectional study of 25,000 participants, those experiencing post–COVID-19 condition (PCC) were approximately twice as likely to report depression and anxiety symptoms than other U.S. adults. Among individuals with these symptoms, adults with PCC were just as likely to have received mental health treatment but more likely to report cost-related barriers to accessing therapy. Care pathways for PCC should consider prioritizing mental health screening and affordable treatment.  Authors: Hiten Naik, M.D., ...

Disparities in mortality by sexual orientation in a large, prospective cohort of female nurses

2024-04-25
About The Study: In an otherwise largely homogeneous sample of female nurses, participants identifying as lesbian or bisexual had markedly earlier mortality during the study period compared with heterosexual women. These differences in mortality timing highlight the urgency of addressing modifiable risks and upstream social forces that propagate and perpetuate disparities.  Authors: Sarah McKetta, M.D., Ph.D., of Harvard University in Boston, is the corresponding author. To access the embargoed ...

National trial safely scaled back prescribing of a powerful antipsychotic for the elderly

2024-04-25
Warning letters from Medicare can safely cut prescribing of a powerful but risky antipsychotic, according to a new study at Columbia University Mailman School of Public Health. Researchers used Medicare data to study the effects of the letters on hundreds of thousands of older adults with dementia. They found a significant and lasting reduction in prescribing but no signs of adverse effects on patient health. The findings are published in JAMA Network Open. “Our study shows that low-cost letter interventions can safely reduce antipsychotic prescribing to patients with dementia,” said Adam Sacarny, PhD, assistant professor of Health Policy and Management at Columbia Mailman School. ...

Premature mortality higher among sexual minority women, study finds

2024-04-25
Key takeaways: A new study led by the Harvard Pilgrim Health Care Institute examined differences in premature mortality by sexual orientation among a large group of women followed for three decades. Findings show that sexual minority women died much sooner than heterosexual women, with bisexual women having the most pronounced differences. This work highlights the urgent need to address sexual orientation-related inequities in preventable illness, including a focus on the systems and laws that ...

Extreme long-term research shows: Herring arrives earlier in the Wadden Sea due to climate change

Extreme long-term research shows: Herring arrives earlier in the Wadden Sea due to climate change
2024-04-25
Due to the changing climate, young herring arrive in the Wadden Sea earlier and earlier in spring. That is shown in a new publication by NIOZ ecologists Mark Rademaker, Myron Peck and Anieke van Leeuwen, in this month's journal Global Change Biology. "The fact that we were able to demonstrate this, was only due to very consistently, for more than 60 years, and continuously sampling the fish every spring and every fall with exactly the same fyke every time", Rademaker says. "Recognizing this kind of change requires extreme precision ...

With hybrid brains, these mice smell like a rat

With hybrid brains, these mice smell like a rat
2024-04-25
NEW YORK, NY--If mice ever wonder what it’s like to experience the world as a rat, some are now able to live that dream, at least when it comes to the sense of smell.  Researchers led by Columbia University's Kristin Baldwin have created mice with hybrid brains – part mouse, part rat – that sense the odors of the world with their rat neurons.   It is the first time that an animal has been able to use the sensory apparatus of another to sense and respond accurately to the world ...

Philippines' counter-terrorism strategy still stalled after 7 years since the ‘ISIS siege’ on Marawi

2024-04-25
Following the 2017 siege of Marawi, the Philippines' counter-terrorism efforts have faced an increasingly complex and unpredictable landscape. While authorities have claimed victory, one which garnered global media attention during the peak of ISIS reign in Syria and Iraq, the aftermath of Marawi highlights the urgent need for a comprehensive reassessment of the country's counter-terrorism strategy. A new study, led by experts in security and terrorism studies at the University of Portsmouth, provides a thorough examination of the terrorist ...

BU doc honored by the American College of Surgeons

2024-04-25
(Boston)—Dane Scantling, DO, MPH, FACS, assistant professor of surgery at Boston University Chobanian & Avedisian School of Medicine, has been awarded the C. James Carrico, MD, FACS, Faculty Research Fellowship for the Study of Trauma and Critical Care from the American College of Surgeons. The two-year, $80,000 award will support his project, "Improving Equity and Access to Trauma Care for Victims of Firearm Violence."   Firearm violence (FV) rates have risen to levels not seen ...

Airborne single-photon lidar system achieves high-resolution 3D imaging

Airborne single-photon lidar system achieves high-resolution 3D imaging
2024-04-25
WASHINGTON — Researchers have developed a compact and lightweight single-photon airborne lidar system that can acquire high-resolution 3D images with a low-power laser. This advance could make single-photon lidar practical for air and space applications such as environmental monitoring, 3D terrain mapping and object identification. Single-photon lidar uses single-photon detection techniques to measure the time it takes laser pulses to travel to objects and back. It is particularly useful for airborne applications because it enables highly accurate 3D mapping of terrain and objects even in challenging environments such as dense vegetation or urban areas. “Using single-photon ...

Stem cell transplants and survival rates on the rise across all racial and ethnic groups

2024-04-25
(WASHINGTON, April 25, 2024) – The volume of hematopoietic cell transplants rose among all racial/ethnic groups, but grew faster among African Americans and Hispanics compared with Non-Hispanic white individuals, mirroring changes in population growth rates. Survival after both autologous hematopoietic cell transplant (autoHCT) and allogeneic hematopoietic transplant (alloHCT) improved over time across racial/ethnic groups, though non-Hispanic African Americans still have worse outcomes, according ...
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