Cardiovascular risk score predicts multiple eye diseases
2026-01-08
January 7, 2026 –A new study from UCLA Health shows that a cardiovascular risk score already used routinely in primary care can predict who will develop serious eye diseases years later. Researchers found that people with higher cardiovascular risk scores were significantly more likely to develop conditions including age-related macular degeneration, diabetic retinopathy, glaucoma, retinal vein occlusion, and hypertensive retinopathy. The study appears in Ophthalmology.
Why it matters
Millions of Americans lose vision to eye diseases that often go undetected until significant damage has occurred. Early identification of at-risk individuals could ...
Health: estimated one in ten British adults used or interested in GLP-1 medications for weight loss
2026-01-08
In early 2025, around 4.9 million British adults — almost one in ten — are estimated to have recently used, or expressed interest in using, glucagon-like peptide-1 (GLP-1) or dual GLP-1/glucose-dependent insulinotropic polypeptide (GIP) receptor agonist medications to support weight loss. The findings, which are based on a nationally representative household survey of 5,260 British adults, are published in BMC Medicine.
GLP-1 and GLP-1/GIP medications help lower blood sugar, support weight loss, and reduce the risk ...
Exercise to treat depression yields similar results to therapy
2026-01-08
Exercise may reduce symptoms of depression to a similar extent as psychological therapy, according to an updated Cochrane review. When compared with antidepressant medication, exercise also showed a similar effect, but the evidence was of low certainty.
Depression is a leading cause of ill health and disability, affecting over 280 million people worldwide. Exercise is low-cost, widely available, and comes with additional health benefits, making it an attractive option for patients and healthcare providers.
The review, conducted by researchers from the University of Lancashire, examined 73 randomized ...
Whooping cough vaccination for pregnant women strengthens babies’ immune system
2026-01-08
Vaccinating women during pregnancy leads to the transfer of antibodies to their newborns. These antibodies were detected not only in blood, but also in the nasal mucosa, the site where whooping cough bacteria enter the body. This has been shown by international research led by Radboud university medical center. ‘The fact that these antibodies reach the nasal mucosa has not been demonstrated before and highlights how effective this vaccination is’.
Since 2019, pregnant women in the Netherlands have been offered a vaccination against whooping cough (pertussis) for their unborn child, known as the 22-week ...
Dramatic decline in new cases of orphanhood in Uganda driven by HIV treatment and prevention programs
2026-01-08
The scale-up of HIV treatment and prevention programs has led to remarkable declines in orphanhood rates in Rakai, Uganda, according to a new study at Columbia University Mailman School of Public Health. Antiretroviral therapy (ART) availability has been the primary driver of these improvements, underscoring the critical importance of sustained investment in HIV programs. Findings from the study, " Incidence and prevalence of orphanhood in Rakai, Uganda: a population-based cohort study, 1995–2022" are published in The Lancet Global Health.
Using data from the Rakai Community ...
Stopping weight loss drugs linked to weight regain and reversal of heart health markers
2026-01-08
Stopping weight loss drugs is followed by weight regain and reversal of beneficial effects on heart and metabolic health markers such as high cholesterol and high blood pressure, finds a study published by The BMJ today.
It shows that the average rate of weight regain is 0.4kg/month after stopping treatment, with weight and risk markers for diabetes and heart disease predicted to return to pre-treatment levels in less than two years.
It also finds that the rate of weight regain after stopping weight loss drugs is almost 4 times faster than after diet and physical activity ...
Higher intake of food preservatives linked to increased cancer risk
2026-01-08
Higher intake of food preservatives, widely used in industrially processed foods and beverages to extend shelf-life, is associated with a modestly increased risk of cancer, finds a study from France published by The BMJ today.
While further research is needed to better understand these links, the researchers say these new data call for the re-evaluation of regulations governing the use of these additives by the food industry to improve consumer protection.
Preservatives are substances added to packaged foods to extend shelf life. Some experimental studies have shown that certain preservatives ...
Mass General Brigham–developed cholera vaccine completes phase 1 trial
2026-01-08
Clinical trial shows promising results for PanChol, a single-dose oral vaccine aimed at the up to 4 million annual cholera cases worldwide
A team of scientists and physicians at Mass General Brigham has developed a single-dose oral cholera vaccine and tested it in a phase 1 clinical trial, with results published in The Lancet Infectious Diseases.
“The devastating cholera outbreak in Haiti in 2010 triggered my desire to create a new oral live-attenuated cholera vaccine,” said co–senior author Matthew ...
First experimental validation of a “150-year-old chemical common sense” direct visualization of the molecular structural changes in the ultrafast anthracene [4+4] photocycloaddition reaction
2026-01-08
Overview
Anthracene—a hydrocarbon known for its strong luminescence and high photo-reactivity—has long been considered one of the most iconic and widely studied organic molecules. Its [4+4] photocycloaddition reaction, first reported in 1867, has underpinned the development of countless photo-functional materials, including actuators, adhesives, and chromic systems.
Despite being a textbook reaction, the structural changes during this photoreaction occur in an extremely short time window (10⁻⁸–10⁻⁶ s), placing the process beyond direct experimental observation for more than a century. Consequently, controlling and visualizing ...
Lack of support for people on weight loss drugs leaves them vulnerable to nutritional deficiencies, say experts
2026-01-08
People prescribed the new generation of weight loss drugs may not receive sufficient nutritional guidance to support safe and sustainable weight loss, leaving them vulnerable to nutritional deficiencies and muscle loss, say experts at UCL and the University of Cambridge.
In research published today in Obesity Reviews, the team, led by Dr Marie Spreckley from the University of Cambridge, found a lack of robust evidence surrounding nutritional advice and support and the impact this has on factors such as calorie intake, body composition, protein adequacy, and patient experiences.
Weight ...
Dogs’ dinners can have greater climate impact than owners’
2026-01-08
Dogs fed on premium, meat-rich pet food can have a bigger dietary carbon pawprint than their owners, according to the largest study into dog food’s climate impact.
In particular, wet, raw and meat-rich products are associated with substantially higher greenhouse gas emissions than dry dog food.
Overall, the production of ingredients used in UK dog food is estimated to contribute around one per cent of the country’s total greenhouse gas emissions.
The findings highlight the need for greater transparency and better labelling of dog food ingredients to help consumers make informed choices, as pet ownership continues to rise, experts say.
Scientists ...
Are you ready to swap salmon for sprats and sardines?
2026-01-08
Millions of Britons could be ready to swap imported fish for home‑caught favourites like sardines, sprats and anchovies – according to a new study from the University of East Anglia (UEA).
A new report reveals that more than 40 per cent of consumers are willing to experiment with fish they’ve never tried before.
The study suggests the UK is overlooking a major opportunity to improve national health and bolster local economies by embracing its own rich stocks of small, nutritious fish.
The study was led by researchers at UEA’s Centre for Social and Economic Research ...
1.6 million UK adults used weight loss drugs in past year
2026-01-08
An estimated 1.6 million adults in England, Wales and Scotland used drugs such as Wegovy and Mounjaro to help lose weight between early 2024 and early 2025, according to a new study by UCL (University College London) researchers.
The research, published in BMC Medicine and funded by Cancer Research UK, found that an additional 3.3 million people said they would be interested in using weight loss drugs over the next year.
The team looked at data from 5,260 people who were representative of the general population ...
American College of Cardiology comments on new dietary guidelines for Americans
2026-01-07
American College of Cardiology President Christopher M. Kramer, MD, FACC, issued the following statement on the release of new Dietary Guidelines for Americans by the U.S. Department of Health and Human Services (HHS) and U.S. Department of Agriculture.
“The ACC acknowledges and appreciates the release of new federal nutrition guidance and remains committed to helping clinicians and patients use it to support heart health,” said ACC President Christopher M. Kramer, MD, FACC.
“We welcome the inclusion of several important science-based recommendations, ...
American Society of Gene & Cell Therapy and Orphan Therapeutics Accelerator partner to advance and commercialize promising rare disease treatments
2026-01-07
MILWAUKEE, WI and CAMBRIDGE, MA – January 7, 2026 – The American Society of Gene & Cell Therapy (ASGCT), the leading professional organization for the advancement of cell and gene therapies (CGTs), and the Orphan Therapeutics Accelerator (OTXL), a non-profit biotech focused on completing development and enabling access to stalled rare disease treatments, today announced a partnership to establish CGTxchange, a jointly owned entity that will serve as a clearinghouse and marketplace for deprioritized CGTs.
The new joint venture will address a growing and urgent challenge facing the CGT field: policy and economic shifts in ...
One in 14 patients having day case surgery have new or worse chronic pain 3 months after their operation
2026-01-07
Two new studies published in Anaesthesia (the journal of the Association of Anaesthetists) analysing pain and other factors connected with day surgery in the UK show that around 1 in 8 patients having day-case surgery end up not going home and instead are admitted to hospital for various complications. Furthermore, one in 14 go on to develop chronic pain at the operative site after the procedure.
The studies are by Dr Martha Belete, Torbay and South Devon NHS Foundation Trust, Torbay, Devon, UK and Dr Adam Brayne, University Hospitals Plymouth NHS Trust, ...
New study highlights link between eviction rates and gun violence
2026-01-07
Violent crime has fallen to historic lows in Chicago, although gun violence continues to plague neighborhoods with concentrated poverty. A 2023 study of five major cities showed that more than 55% of shootings occurred in just 9% of total census tracts, and that small increases in things like poverty, unemployment, or limited access to health care are associated with large increases in firearm violence.
Yet not every neighborhood that struggles with these challenges also has high rates of violence. ...
Heatwaves heat up soil but not toxin levels in rice, study finds
2026-01-07
In a surprising twist amid rising climate concerns, new research shows that scorching soil temperatures during extreme heatwaves do not necessarily boost the uptake of toxic elements like arsenic in rice crops. This finding, from a real world experiment during China's record breaking 2022 heatwaves, challenges fears that global warming will poison staple foods.
"Our study reveals that soil warming alone, decoupled from air temperature rises, does not inevitably ramp up arsenic or heavy metal accumulation in rice grains," said Sha Zhang, ...
Digital modeling reveals where construction carbon emissions really come from
2026-01-07
A new study shows how digital building models can be used to pinpoint where carbon emissions occur across a building’s entire life cycle, offering designers and policymakers a powerful tool to reduce the climate footprint of the construction industry.
Researchers developed an integrated method that combines Building Information Modeling and Life Cycle Assessment to calculate carbon emissions from the earliest design stage through construction, operation, and eventual demolition. Using a real office building in China as a case study, the team demonstrated how emissions can be quantified in detail and how targeted reduction ...
Turning farm waste into water filters
2026-01-07
Researchers at the University of Delaware have transformed discarded corn cobs and other agricultural byproducts into high performance biochar filters that capture both ammonia and tiny plastic particles from water. In laboratory tests, optimized biochar removed up to 64 percent of dissolved ammonia and more than 97 percent of polystyrene micro and nanoplastics without leaching harmful chemicals back into the water. The study points to a practical way to clean polluted water while recycling agricultural waste and locking ...
New study shows how the spleen helps the immune system accept a transplant
2026-01-07
MINNEAPOLIS/ST. PAUL (1/07/2026) —New research from the University of Minnesota Medical School offers a new view of how the immune system responds to organ transplants. The findings, published today in Science Advances External link that opens in the same window, show that T cell exhaustion – traditionally viewed as a pathological failure of the immune system — can instead play a protective role by helping the body tolerate a donated organ.
The study identifies the spleen as a key control center for transplant tolerance. Researchers found that administering apoptotic donor leukocytes (ADLs) triggers the expansion of donor-specific regulatory T cells, ...
New Mayo Clinic study advances personalized prostate cancer education with an EHR-integrated AI agent
2026-01-07
PHOENIX — Mayo Clinic researchers have developed and evaluated MedEduChat, an electronic health record (EHR) that works with a large language model to provide accurate, patient-specific prostate cancer education.
The findings are published in Nature Portfolio Digital Medicine and highlight a new approach to delivering timely, individualized guidance for people navigating a prostate cancer diagnosis.
Cancer patients often face uncertainty as they process complex information about their diagnosis and treatment options. Limited time with ...
Researchers identify novel therapeutic target to improve recovery after nerve injury
2026-01-07
Peripheral nerve injury reduces the ability of macrophages to clear dead or dying cells – a process known as efferocytosis – leading to chronic pain
Restoring efferocytosis ability reduced neuropathic pain in lab models
Efferocytosis is a potential therapeutic target for chronic neuropathic pain
Researchers at The University of Texas MD Anderson Cancer Center have discovered that targeting a specific immune process could help improve recovery after nerve injury and reduce chronic pain.
The study, published in Proceedings of the National Academy of Sciences (PNAS), was led by Peter Grace, Ph.D., associate ...
Microbes in breast milk help populate infant gut microbiomes
2026-01-07
Most conversations about breast milk tend to focus on topics like nutrients, antibodies and bonding time rather than bacteria. But it turns out that human milk carries its own tiny community of microbes, and those passengers may help shape a baby’s developing gut microbiome — which in turn can impact nutrient absorption, metabolic regulation, immune system development, and more.
A new study published in Nature Communications provides one of the most detailed portraits yet of how different combinations of bacteria in human milk contribute to the assembly of infants’ ...
Reprogramming immunity to rewrite the story of Type 1 diabetes
2026-01-07
In the battle against type 1 diabetes (T1D), one researcher at the Medical University of South Carolina (MUSC) is leading a bold new front. With $1 million in funding from Breakthrough T1D, the leading global T1D research and advocacy organization, Leonardo Ferreira, Ph.D., assistant professor of Pharmacology and Immunology, and his collaborators at partnering institutions will explore a new approach to treating – and potentially curing – the disease.
The team aims to reimagine how the immune system interacts with the pancreas by combining stem cell biology, immunology and transplantation science. The project’s goal is deceptively simple: to restore beta cell ...
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