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A new strategy for immune tolerance

2025-12-22
A research team at the Nano Life Science Institute (WPI-NanoLSI) and the Faculty of Medicine at Kanazawa University has developed a new class of engineered extracellular vesicles (EVs) capable of inducing antigen-specific regulatory T cells (Tregs), the immune cells that play a central role in suppressing excessive immune responses. The findings, now published in Drug Delivery, may pave the way for next-generation therapies for autoimmune and allergic diseases, where unwanted immune activation must ...

Super Mario Bros. help fight burnout: New study links classic games to boosted happiness

2025-12-22
(Toronto, December 22, 2025) A new study published by JMIR Serious Games reports that popular video games, such as the Super Mario Bros. and Yoshi games, may offer meaningful emotional benefits for young adults. The research, titled “Super Mario Bros. and Yoshi Games’ Affordance of Childlike Wonder and Reduced Burnout Risk in Young Adults: In-Depth Mixed Methods Cross-Sectional Study,” found that these lighthearted, familiar games can spark a sense of childlike wonder that boosts overall happiness, which in turn reduces burnout risk. The research team conducted in-depth interviews with university ...

Deepest gas hydrate cold seep ever discovered in the arctic: International research team unveils Freya Hydrate Mounds at 3,640 m depth.

2025-12-22
Deepest Gas Hydrate Cold Seep ever discovered in the Arctic: international research team unveils Freya Hydrate Mounds at 3,640 m Depth.   A multinational scientific team led by UiT has uncovered the deepest known gas hydrate cold seep on the planet.  The discovery was made during the Ocean Census Arctic Deep – EXTREME24 expedition and reveals a previously unknown ecosystem thriving at 3,640 metres on the Molloy Ridge in the Greenland Sea. The groundbreaking findings regarding the Freya Hydrate Mounds, which hold scientific significance and implications for Arctic ...

Integrating light and structure: Smarter mapping for fragile wetland ecosystems

2025-12-22
Accurate classification of wetland vegetation is essential for biodiversity conservation and carbon cycle monitoring. This study developed an adaptive ensemble learning (AEL-Stacking) framework that combines hyperspectral and light detection and ranging (LiDAR) data captured by UAVs to precisely identify vegetation species in karst wetlands. The approach achieved up to 92.77% accuracy—substantially outperforming traditional models—and revealed how spectral and structural features jointly improve ecosystem mapping and restoration strategies. Karst wetlands are globally significant ecosystems that regulate ...

ACA-SIM: A robust way to decode satellite signals over complex waters

2025-12-22
A new study introduces ACA-SIM (atmospheric correction based on satellite–in situ matchup data), a neural-network-based atmospheric correction algorithm that uses real satellite–Aerosol Robotic Network-Ocean Color (AERONET-OC) matchups to improve the accuracy of atmospheric correction over coastal waters. By learning from real-world satellite radiance and in-situ reflectance data, ACA-SIM significantly reduces errors and striping artifacts in ocean color products, outperforming existing models in turbid water and complex-aerosol conditions such as the Bohai Sea, North Africa dust ...

Probiotics can restore gut microbiome in breastfed infants

2025-12-22
Washington, D.C.—In recent years, scientists have learned that key beneficial infant gut bacteria Bifidobacterium infantis are disappearing from infants in high-resource areas such as the United States and Europe. Now, a new study published in the journal mSphere found that supplementing exclusively breastfed infants with a probiotic, B. infantis EVC001, between 2 and 4 months of age can successfully restore beneficial bacteria in their gut. “The REMEDI study shows that it’s not too late to restore a healthy gut microbiome in breastfed infants. B. infantis can successfully take hold even after the newborn period,” ...

AI could help predict nutrition risks in ICU patients, study finds

2025-12-22
New York, NY [December 22, 2025]—A new study by researchers at the Icahn School of Medicine at Mount Sinai suggests that artificial intelligence (AI) could help predict which critically ill patients on ventilators are at risk of underfeeding, potentially enabling clinicians to adjust nutrition early and improve patient care. Details of the study were published in the December 17 online issue of Nature Communications. The first week on a ventilator is especially important for providing proper nutrition, since patients’ needs often shift ...

Federal EITC has unexpected result, researchers say – it decreases domestic violence

2025-12-22
Fifty years since the federal earned income tax credit went into effect and a team of researchers from UConn and City University of New York have identified an unintended benefit of the antipoverty program – a significant reduction in rates of intimate partner violence among unmarried women. “There’s been enough literature to show that good things happen because of the earned income tax credit, but what was surprising to us is the relatively large effect it has on intimate partner violence,” says UConn’s David Simon, an associate professor of economics and study co-author. ...

Researchers identify gene that calms the mind and improves attention in mice

2025-12-22
Attention disorders such as ADHD involve a breakdown in our ability to separate signal from noise. The brain is constantly bombarded with information, and focus depends on its ability to filter out distractions and detect what matters. Stimulant medications improve attention by boosting activity in circuits known to govern attention, such as the prefrontal cortex. But a new study reveals a surprising alternative: reduce background activity as a way of turning down extraneous noise.  In a paper published in Nature Neuroscience, ...

Artificial metabolism turns waste CO2 into useful chemicals

2025-12-22
In a breakthrough that defies nature, Northwestern University and Stanford University synthetic biologists have created a new artificial metabolism that transforms waste carbon dioxide (CO2) into useful biological building blocks. In the new study, the team engineered a biological system that can convert formate — a simple liquid molecule easily made from CO2 — into acetyl-CoA, a universal metabolite used by all living cells. As a proof of concept, the engineers then used the same system to convert acetyl-CoA into malate, ...

Ancient sea anemone sheds light on animal cell type evolution

2025-12-22
One of the biggest quests in biology is understanding how every cell in an animal’s body carries an identical genome yet still gives rise to a kaleidoscope of different cell types and tissues. A neuron doesn’t look nor behave like a muscle cell but has the same DNA. Researchers think it comes down to how cells allow different parts of the genome to be read. Controlling these permissions are regulatory elements, regions of the genome which switch genes on or off. A detailed overview of how they do this is largely restricted to a handful of classic model organisms like mice and fruit flies. For the first time, researchers have created ...

Begging gene leads to drone food

2025-12-22
Is complex social behaviour genetically determined? Yes, as a team of biologists from Heinrich Heine University Düsseldorf (HHU) together with colleagues from Bochum and Paris discovered while studying bees. They identified a genetic factor that determines the begging behaviour of drones, which they use to obtain food socially. They are now publishing their findings in the scientific journal Nature Communications. Male bees, or “drones”, do not have an easy time obtaining essential proteins. This ...

How climate policies that incentivize and penalize can drive the clean energy transition

2025-12-22
A new study from a team of researchers that includes faculty from the University of California San Diego and Princeton University shows how a mix of subsidies for clean energy and taxes on pollution can significantly reduce greenhouse gas emissions that cause climate change. While these kinds of policy mixes are widely used in the real world, the the study, published in Nature Climate Change is the first to show how the combination of such policies can be simulated in economic models that are the backbone of nearly all climate policy discussions – including ...

Can community awareness campaigns in low-resource areas improve early diagnosis of colorectal cancer?

2025-12-22
In low-resource regions such as Nigeria, most people with colorectal cancer are diagnosed too late for curative treatment options. A community awareness campaign in the country helped clinicians detect both early-stage and advanced colorectal cancer in patients who had not been aware that they should be screened. That’s according to a study published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society. For the study, investigators ...

Stardust study resets how life’s atoms spread through space

2025-12-22
Starlight and stardust are not enough to drive the powerful winds of giant stars, transporting the building blocks of life through our galaxy. That’s the conclusion of a new study from Chalmers University of Technology, Sweden, of red giant star R Doradus. The result overturns a long-held idea about how the atoms needed for life are spread. “We thought we had a good idea of how the process worked. It turns out we were wrong. For us as scientists, that’s the most exciting result”, says Theo Khouri, astronomer at Chalmers and joint leader of the study. To understand the origins ...

Practical education: Clinical scenario-based program development

2025-12-22
To reduce mortality rates, fall and tumble rates, and delirium incidence among hospitalized patients, it is crucial for nurses to learn Evidence-Based Practice (EBP). To achieve this, developing effective EBP education programs is essential. However, traditional EBP education programs have faced challenges, such as not covering all aspects of the EBP process and lacking rigorous evaluation methods for these programs. Dr. Hideaki Furuki and colleagues at Osaka Metropolitan University’s Graduate School of Nursing ...

The impact of family dynamics on eating behaviour – how going home for Christmas can change how you eat

2025-12-22
As the holiday season approaches, many families will gather around the dinner table, sharing meals and memories. But what if the way we eat during these gatherings is shaped by more than just tradition? Psychology research shows that our families and upbringing have a massive impact on how we eat and our relationship towards food. In fact, these influences are so profound that they can mean some people dread visiting family for the festivities. In an in-depth study of the psychology of eating, Professor in Health Psychology Jane Ogden delves into the profound impact of family dynamics on eating behaviour, ...

Tracing the quick synthesis of an industrially important catalyst

2025-12-20
Tokyo, Japan – Researchers from Tokyo Metropolitan University have successfully traced the mechanism behind how an industrially important “superbase” catalyst is synthesized in a faster, microwave-assisted reaction. They took measurements using X-rays while the reaction occurred, uncovering how small precursor molecules were formed first before they clustered to create the final product. Their insights promise finer control over a promising technology for speeding up chemical synthesis in industry.   Polyoxometalates are industrially ...

New software sheds light on cancer’s hidden genetic networks

2025-12-19
University of Navarra (Spain) researchers have developed RNACOREX, a new open-source software capable of identifying gene regulation networks with applications in cancer survival analysis. The tool, created by scientists at the Institute of Data Science and Artificial Intelligence (DATAI), members of the Cancer Center Clínica Universidad de Navarra, has been validated with data from thirteen tumor types from the international consortium The Cancer Genome Atlas (TCGA). Published in PLOS Computational ...

UT Health San Antonio awarded $3 million in CPRIT grants to bolster cancer research and prevention efforts in South Texas

2025-12-19
SAN ANTONIO, Dec. 19, 2025 – UT Health San Antonio, the academic health center of The University of Texas at San Antonio (UT San Antonio), received nearly $3 million in new academic and prevention awards as part of the latest funding round announced by the Cancer Prevention Research Institute of Texas (CPRIT). The state agency, which focuses on funding evidence-based cancer research and prevention efforts, has now awarded UT Health San Antonio almost $170 million since 2010. Expanding access to preventive salpingectomy in South Texas Kate Lawrenson, PhD, associate professor in the Department of Obstetrics and Gynecology at the Joe R. and Teresa ...

Third symposium spotlights global challenge of new contaminants in China’s fight against pollution

2025-12-19
The Third Symposium on New Contaminant Control held in Shanghai on September 13–14 2025 highlighted how newly recognized pollutants are reshaping China’s environmental agenda. These substances including persistent organic pollutants endocrine disruptors antibiotics and microplastics are often invisible yet can linger in the environment accumulate in living organisms and pose long term risks to ecosystems and human health. Quote and key message “New contaminants do not always make headlines ...

From straw to soil harmony: International team reveals how biochar supercharges carbon-smart farming

2025-12-19
What if the secret to climate-friendly farming wasn’t in futuristic tech—but in how we manage what’s already on the field? Imagine turning leftover maize stalks not into smoke from open burning, but into a powerful soil ally—especially when paired with its charred cousin, biochar. That’s exactly what a new international study has uncovered: a simple yet transformative strategy that cuts carbon emissions, boosts soil health, and even encourages microbes to work together like never before. Published on October 27, 2025, in the open-access journal Carbon Research (Volume 4, Article 68), this collaborative research bridges Moscow and Guangzhou to deliver one of the ...

Myeloma: How AI is redrawing the map of cancer care

2025-12-19
MIAMI, FLORIDA (Dec 19, 2025) – C. Ola Landgren, M.D., Ph.D., received HealthTree Foundation’s prestigious 2025 Innovation Award for his work in developing CORAL, a new research tool that leverages AI to predict individual outcomes and guide treatment decisions in patients with multiple myeloma. Using deep learning to read standard bone marrow biopsy slides like pages in a book, CORAL spots patterns in a patient’s cancer to accurately predict genetic subtypes and patient outcomes, bypassing the traditional need for expensive, time-consuming genomic tests. Landgren, director of the Sylvester Myeloma Institute at Sylvester Comprehensive ...

Manhattan E. Charurat, Ph.D., MHS invested as the Homer and Martha Gudelsky Distinguished Professor in Medicine at the University of Maryland School of Medicine

2025-12-19
Baltimore, MD — The University of Maryland School of Medicine (UMSOM) proudly announces the investiture of Manhattan E. Charurat, PhD, MHS as the Homer and Martha Gudelsky Distinguished Professor in Medicine, one of the institution’s most prestigious academic honors.  The ceremony opened with warm welcomes delivered by Heather Culp, JD, Senior Vice President and Chief Philanthropy Officer, Senior Associate Dean at University of Maryland Medicine, and Shyam Kottilil, MD, PhD, Interim Director of the Institute of Human Virology (IHV). Mark T. Gladwin, MD, Dean of the University of Maryland School of Medicine, offered ...

Insilico Medicine’s Pharma.AI Q4 Winter Launch Recap: Revolutionizing drug discovery with cutting-edge AI innovations, accelerating the path to pharmaceutical superintelligence

2025-12-19
On December 10, Insilico Medicine, a clinical stage generative artificial intelligence (AI)-driven biotechnology company, hosted the fourth edition of its Pharma.AI Quarterly Launch webinar, titled “Epic Year-End Recap & Q4 Winter Updates”. The event drew more than 300 registrants from universities, healthcare institutions, global pharmaceutical companies, and innovative biotech firms worldwide. Insilico's software team showcased the recap of Pharm.AI in 2025,and the latest capabilities through live demos and real‑world case studies.   Key highlights are summarized below: Generative Biologics What improved in  2025: Peptide workflows: template-based ...
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