About The Study: In this randomized clinical trial, home high-intensity aerobic training improved ataxia symptoms, fatigue, and aerobic fitness more than dose-matched home balance training among individuals with cerebellar ataxias, a heterogenous group of disorders characterized by progressive disability due to loss of coordination. Individuals in the aerobic group who continued to train regularly maintained benefits at 1 year. Corresponding Author: To contact the corresponding author, Scott Barbuto, MD, PhD, email sb3779@cumc.columbia.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamaneurol.2025.3421) Editor’s ...

Copenhagen, Denmark: Dry eyes can cause significant discomfort, and the symptoms become more common as we age. However, until now, it was unclear what proportion of the population suffered from the condition, with estimates ranging from 5-50%.  In fact, research presented today (Monday) at the 43rd Congress of the European Society of Cataract and Refractive Surgeons (ESCRS) [1], found that more than half of the general population in the USA and Europe experience dry eyes, yet only 20% of European patients and 17% of US patients were diagnosed, and they can wait years for professional help. Dr Piotr ...

In women with type 2 diabetes (T2D), use of hormone replacement therapy (HRT) skin patches is not associated with a higher risk of blood clots or stroke. However, an increased cardiovascular risk was found for oral HRT, according to a large real-world study being presented at this year’s Annual Meeting of The European Association for the Study of Diabetes (EASD), Vienna (15-19 Sept). Among the findings are an analysis revealing women with T2D who took the oral form of HRT doubled their risk of developing a pulmonary embolism (PE - when a blood clot blocks an artery in the lung) and faced a 21% increased risk of heart disease compared with ...

It is possible to be “fat but fit”, new research being presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Vienna, Austria (15-19 September) suggests. The study of tens of thousands of people in Denmark found that those with a BMI in the overweight category – and even some of those living with obesity – were no more likely to die during the five years of follow-up than those with a BMI of 22.5-<25.0 kg/m2, which is at the top end of the normal weight range. Individuals with a BMI in the middle and lower parts of the normal ...

Cannabis use is linked to an almost quadrupling in the risk of developing diabetes, according to an analysis of real-world data from over 4 million adults, being presented at this year’s Annual Meeting of The European Association for the Study of Diabetes (EASD) in Vienna, Austria (15-19 Sept). Cannabis use is increasing globally with an estimated 219 million users (4.3% of the global adult population) in 2021, but its long-term metabolic effects remain unknown [1]. While some studies have suggested potential anti-inflammatory or weight management properties, others have raised concerns regarding ...

A new synthesis of global evidence finds that experiencing gestational diabetes during pregnancy is linked with a decline in intellectual function among mothers, and may increase the risk of neurodevelopmental disorders, including autism spectrum disorder and attention-deficit/hyperactivity disorder (ADHD) in children. The ongoing systematic review and meta-analysis of 48 observational studies involving over 9 million pregnancies, is being presented at this year’s Annual Meeting of The European Association for the Study of Diabetes (EASD), Vienna (15-19 Sept). The authors say that given the increasing prevalence of gestational diabetes ...

Copenhagen, Denmark: Everybody develops presbyopia as they age – a difficulty in focusing on near objects and text – and often have to resort to reading glasses. However, the solution might be as simple as using special eye drops two or three times a day. A retrospective study of 766 patients presented today (Sunday) at the 43rd Congress of the European Society of Cataract and Refractive Surgeons (ESCRS) [1], found that the majority could read an extra two, three or more lines on the eye chart used for testing near visual acuity (the Jaeger chart) after using specially formulated ...

Copenhagen, Denmark: Patients who have a new type of lens implanted in their eyes during surgery for cataracts or to correct their eyesight have excellent or good vision over distances both near and far, and often no longer need spectacles for reading. Research presented today (Sunday) at the 43rd Congress of the European Society of Cataract and Refractive Surgeons (ESCRS) [1] evaluated outcomes for around 200 patients in 17 sites in Europe and Asia-Pacific who had surgery to implant the TECNIS PureSEETM, a purely refractive extended depth of field (EDF) presbyopia correction Intraocular Lens (IOL). Presbyopia is the condition that affects ...

Copenhagen, Denmark: Researchers have successfully used artificial intelligence (AI) to predict which patients need treatment to stabilise their corneas and preserve their eyesight, in a study presented today (Sunday) at the 43rd Congress of the European Society of Cataract and Refractive Surgeons (ESCRS). [1]   The research focused on people with keratoconus, a visual impairment that generally develops in teenagers and young adults and tends to worsen into adulthood. It affects up to 1 in 350 people. In some cases, the condition can be managed ...

The new class of anti-obesity drugs, glucagon-like peptide-1 receptor agonists (GLP-1RAs), is proving remarkably effective at helping individuals lose weight. However, a new population-wide study being presented at this year’s Annual Meeting of The European Association for the Study of Diabetes (EASD), Vienna (15-19 Sept) finds that half of adults without diabetes who start taking the weight-loss drug semaglutide in Denmark discontinue treatment within a year. “This level of drop off is concerning because these medications aren’t ...

The relative increase in odds of an individual with diabetes developing severe symptoms of depression – and vice versa – is the same, regardless of where they live, a study of over-50s in 18 countries in Europe that is being presented at the Annual Meeting of the European Association for the Study of Diabetes (EASD) in Vienna, Austria (15-19 September) has found. Individuals with depression are more likely to develop diabetes and vice versa.  In addition, previous research has shown that the strength of this association depends on the quality of diabetes ...

The characteristics of type 2 diabetes vary from patient to patient and it has been proposed that the condition is made up of four subtypes. Now, new research being presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Vienna, Austria (15-19 September) shows that smoking increases the risk of the condition, regardless of subtype. The researchers in Sweden, Norway and Finland also found that people with a genetic susceptibility to develop diabetes seem more vulnerable to the adverse effects of smoking. It has previously been suggested that type 2 diabetes (T2D) can be divided into the following subtypes: SIRD (severe ...

Tokyo, Japan – Scientists from Tokyo Metropolitan University have determined the genetic lineage of a now extinct plant population from Nishinoshima, a volcanic island whose frequent eruptions periodically “reset” the vegetation. While they traced the lineage to a nearby island, they discovered distinct genetic quirks due to the rarity of seeds making it there, including a “founder’s effect”. Their findings offer a rare glimpse into the very earliest stages of ecosystem development in an isolated environment.   Nishinoshima, ...

An AI algorithm based only on routine mammogram images plus age can predict a woman’s risk of major cardiovascular disease as well as standard risk assessment methods, finds research published online in the journal Heart. And because it uses existing health infrastructure, routine mammography may offer a cost-effective ’two for one’ effective screening option for women, suggest the researchers. Cardiovascular disease and its risk factors are underrecognised and undertreated in women, and risk prediction algorithms have underperformed in them, point out the researchers. And while newer risk scores perform better in women than in ...

Although Black men die of prostate cancer at twice the rate of the rest of U.S. males, this fact often is not known or considered during appointments with their primary-care clinicians to discuss a common screening test.   The new qualitative study published this week in JAMA Network Open showed that Black men often view their primary-care providers as the gatekeepers to receiving a prostate specific antigen (PSA) test, which is the first step to screening for prostate cancer.  “There is an often-used phrase, ‘Prostate cancer is a cancer one dies with; it’s not a disease you die from,’” ...

Sept. 12, 2025 MSU has a satellite uplink/LTN TV studio and Comrex line for radio interviews upon request. Contact: Jack Harrison: 517-939-9378, harr1565@msu.edu; Kim Ward: 734-224-8377, kward@ msu.edu MSU researchers explore how virtual sports aid mental health[HJ1]  EAST LANSING, Mich. – Physical sports have long been known to help with anxiety and mental health. But can augmented and virtual reality sports games improve psychological well-being and reduce loneliness? Researchers at Michigan State University’s Department of Kinesiology say yes. Assistant professors Sanghoon Kim and Sangchul ...

The story of the princess and the pea evokes an image of a highly sensitive royal young woman so refined, she can sense a pea under a stack of mattresses. When it comes to human biology, it also takes an abnormal individual to sense far beyond its surroundings, in this case, a cancer cell. Now, researchers also know that normal cells can pull a similar trick by working together. Research published in the journal PNAS from engineers at Washington University in St. Louis offers a clearer picture of how cells can sense beyond their direct environment. The research can help further the understanding of how cancer moves and point to potential targets to stop that ...

Many scientific discoveries are serendipitous—the result of chance. Seeing evolution in action in a cheese cave turned out to be exactly that for Benjamin Wolfe, associate professor of biology, and his colleagues. Back in 2016, Wolfe convinced his former post-doc advisor to drive with him to Jasper Hill Farm in Vermont to get samples of a special cheese called Bayley Hazen Blue, a ruse for her boyfriend to propose marriage at the spot where they first met. Wolfe ended up keeping that cheese in the freezer in his lab. “I’m notorious for not throwing samples away just in case we might ...

LA JOLLA, CA—What compels someone to keep engaging in alcohol use, even if it damages their health, relationships and wellbeing? A new study from Scripps Research offers an important clue: a small midline brain region plays a key role in how animals learn to continue drinking to avoid the stress and misery of withdrawal. In a new study, published in Biological Psychiatry: Global Open Science on August 5, 2025, the Scripps Research team zeroed in on a set of brain cells in the paraventricular nucleus of the thalamus (PVT) in rats. They found that this region becomes more active, driving strong relapse behavior, when rats learn to associate ...

September 12, 2025 — Interventions to address firearm accessibility and related dangers should account not only for direct exposure to violence but also for complex psychosocial pathways through which firearms affect mental health across populations, according to a systematic scoping review published in the September/October issue of Harvard Review of Psychiatry, part of the Lippincott portfolio from Wolters Kluwer. Rodolfo Furlan Damiano, MD, PhD, of the Institute of Psychiatry at the ...

Research conducted on mice has identified that the rapid response of a specific type of defense cell is essential for controlling Oropouche virus infections and preventing serious neurological damage. Without treatment, “Oropouche fever” causes symptoms including headaches, muscle and joint pain, skin rashes, and vomiting. In severe cases, it can lead to meningitis and encephalitis. Pregnant women are at risk of complications, including miscarriage. These findings will contribute to future studies on developing therapies and vaccines against the disease. The Oropouche virus is ...

The National Science Foundation (NSF) recently awarded leaders at the University of Cincinnati and Kent State University a $3 million grant to create a program that will make research resources more accessible for some smaller institutions and advance projects more efficiently across universities with cost savings.    The Supporting and HArmonizing Research Endeavors (SHARE) initiative is being led by Ohio co-principal investigators Jane Strasser at UC, Kent State University’s Douglas Delahanty and James Reecy at Iowa State University. SHARE aims to increase regional research opportunities by streamlining administration, ...

An ancient DNA analysis of the remains of several mastodons, including those which roamed along the Pacific and Atlantic coasts of North America, has revealed the Ice Age giants migrated vast distances in response to shifting climates and were far more genetically diverse than previously known. In the study published today in the journal Science Advances, researchers from McMaster University and Harvard provide new evidence which significantly revises and reshapes our understanding of the species’ deeply complex evolutionary history. Well-preserved ...

Kyoto, Japan -- The concept of quantum entanglement is emblematic of the gap between classical and quantum physics. Referring to a situation in which it is impossible to describe the physics of each photon separately, this key characteristic of quantum mechanics defies the classical expectation that each particle should have a reality of its own, which gravely concerned Einstein. Understanding the potential of this concept is essential for the realization of powerful new quantum technologies. Developing such technologies will require the ability ...

A UCLA research team has found a new way to prompt the immune system to kill cells infected with cytomegalovirus (CMV), a life-threatening infection that is particularly deadly in immunocompromised people. They did this by engineering antibodies that direct the immune system’s T-cells to kill cells infected with the virus, which poses a danger for people such as those who have undergone organ transplants or who have AIDS.  Infection with CMV can also lead to deafness in infants when the virus is transmitted from the mother during pregnancy. The findings could pave an alternative ...