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Addiction neuroscience leader reveals how brain circuits drive behavioral disorders

Addiction neuroscience leader reveals how brain circuits drive behavioral disorders
2024-12-17
CHARLESTON, South Carolina, USA, 17 December 2024 - In a comprehensive Genomic Press Interview published today in Brain Medicine, renowned neuroscientist Dr. Peter Kalivas reveals crucial insights into how brain circuits drive addictive behaviors and discusses potential new drug targets for treating behavioral disorders. Dr. Kalivas, Distinguished University Professor at the Medical University of South Carolina, has transformed our understanding of addiction neuroscience through his pioneering work on the tetrapartite synapse - a complex cellular structure that includes neurons, astroglia, and the extracellular matrix. His ...

Neuroscientist maps brain's fundamental calculations in learning and social interaction

Neuroscientist maps brains fundamental calculations in learning and social interaction
2024-12-17
PHILADELPHIA, Pennsylvania, USA, 17 December 2024 - In a comprehensive Genomic Press Interview, Dr. Munir Gunes Kutlu, Assistant Professor at Temple University's Center for Substance Abuse Research, unveils revolutionary findings about how our brains process fundamental learning calculations and social interactions. "Our research has identified specific neural mechanisms that transform sensory inputs into behavioral outputs," says Dr. Kutlu. "We've discovered that the brain's dopamine system works in more sophisticated ways than previously understood, particularly in how it processes information about environmental cues and rewards." The interview, published ...

Attitudes toward psychedelic therapy reveal both promise and caution, new study finds

Attitudes toward psychedelic therapy reveal both promise and caution, new study finds
2024-12-17
ATLANTA, Georgia, USA, 17 December 2024 - In a comprehensive Genomic Press Interview with researchers from Emory University, a new study published today reveals complex attitudes toward psychedelic therapy, with detailed statistics showing both strong support for potential benefits and significant awareness of risks. The research, published in the journal Psychedelics, surveyed 178 attendees at an academic conference focused on psychedelics and spiritual care. Among participants, 32 were active psychedelic ...

Leuven researchers discover new connectivity rules in the brain’s visual network

2024-12-17
Leuven, Belgium, 17 December 2024 – Researchers at Neuro-Electronics Research Flanders (NERF), led by Prof. Vincent Bonin, have published two new studies uncovering how visual information is processed and distributed in the brain. The studies reveal the complexity and flexibility of visual information processing in the brain. The visual cortex, a key region for interpreting and processing visual input, plays a crucial role in shaping what we see. Vincent Bonin, a professor at KU Leuven and group leader at NERF, studies the neural circuits that process sensory information. "We often think of visual processing ...

Patients whose allergies cause the sniffles have different fungi living in their noses, compared to healthy people

2024-12-17
Nearly a quarter of Portuguese adults have allergies that cause a runny nose. This respiratory disease, formally called allergic rhinitis and frequently associated with asthma, is a common problem around the world, and the upper airway is a key target for research into the underlying disease processes. Now a global team of researchers has discovered that patients with allergy-induced sniffles and asthma have different fungal colonies or mycobiomes in their noses, suggesting potential lines of enquiry for future treatments.   “We showed that allergic rhinitis ...

The psychological implications of Big Brother’s gaze

2024-12-17
A new psychological study has shown that when people know they are under surveillance it generates an automatic response of heightened awareness of being watched, with implications for public mental health. In a paper published in the journal Neuroscience of Consciousness psychology researchers from the University of Technology Sydney (UTS) worked with 54 participants to examine the effects of surveillance on an essential function of human sensory perception – the ability to detect another person’s gaze. Lead author, Associate Professor of neuroscience and behaviour Kiley Seymour, said previous research has established the effects on conscious behaviour when people know they ...

Sylvester Cancer Tip Sheet for Dec. 2024

2024-12-17
DECEMBER 2024 TIP SHEET: A behavioral expert offers advice for dealing with loss and holiday grief, a physician-scientist explains using “biological age” as a tool to predict early colorectal cancer risk, a cancer leader receives a prestigious award for mentorship, blood cancer experts share research insights that may eventually lead to a cure for multiple myeloma, a recent study shows genetic mutations accumulate in smokers with MDS, two clinical trials show promise for using an antibody to treat high-risk forms of lymphoma and ongoing research seeks answers for higher breast cancer ...

Up to $47 million award supports collaborative eye transplant research co-led by USC

Up to $47 million award supports collaborative eye transplant research co-led by USC
2024-12-17
A federal funding agency that supports high-impact research capable of driving biomedical and health breakthroughs has awarded up to $47 million for a project aimed at moving eye transplants to restore vision closer to reality. The six-year award from the Advanced Research Projects Agency for Health (ARPA-H) Transplantation of Human Eye Allografts (THEA) program is intended to supercharge an interdisciplinary effort to bring eye transplantation forward to clinical trial. To date, only one whole-eye transplant has ever been successfully ...

Corals depend on near neighbours to reproduce

Corals depend on near neighbours to reproduce
2024-12-17
A new study reveals corals must be within only a few metres of each other to successfully reproduce, leaving them vulnerable in a warming world. The international research, led by The University of Queensland’s Professor Peter Mumby, measured the success of a natural spawning event in March this year. “In what came as a surprise, we saw that corals needed to be within 10 metres of one another, and preferably closer than that for fertilisation to take place,” Professor Mumby said. “We knew corals couldn’t be too ...

Most coastal Arctic infrastructure faces instability by 2100

2024-12-17
Researcher contacts: Annett Bartsch, b.geos GmbH, annett.bartsch@bgeos.com (UTC+1 hour) Rodrigue Tanguy, b.geos GmbH, rodrigue.tanguy@bgeos.com (UTC+1 hour) AGU press contact: Rebecca Dzombak, news@agu.org (UTC-5 hours) WASHINGTON — A new study has produced the first map of all coastal communities and infrastructure across the Arctic, showing the vulnerability of the built environment to threats from climate change. Erosion is currently the biggest threat to Arctic coastlines; some places are already experiencing ...

$10.8 million grant supports cutting-edge leukemia research

$10.8 million grant supports cutting-edge leukemia research
2024-12-17
Continuing its role as a leader in leukemia research, Washington University School of Medicine in St. Louis has been awarded a five-year, $10.8 million grant to further its exceptional programs in leukemia and other blood cancers. The grant, from the National Cancer Institute (NCI) of the National Institutes of Health (NIH), renews funding for a prestigious Specialized Program of Research Excellence (SPORE) in leukemia. The NCI’s SPORE program is designed to support translational research that moves discoveries from the lab to the clinic. The WashU Medicine leukemia SPORE is one of only two SPOREs in leukemia in the country. Siteman Cancer Center, ...

Alzheimer’s disease deaths lowest among taxi and ambulance drivers

2024-12-17
Taxi drivers and ambulance drivers, whose jobs require frequent spatial and navigational processing, have the lowest levels of death due to Alzheimer’s disease compared with other occupations, finds a study in the Christmas issue of The BMJ. The findings are observational, so can’t confirm a direct link, but the researchers say they raise the possibility that memory intensive driving occupations, such as taxi and ambulance driving, might be associated with some protection against Alzheimer’s disease. The hippocampus ...

Disney princesses face hidden health risks, warn experts

2024-12-17
Although Disney princesses seem to live happily ever after, they face serious real world health hazards, warn experts in the Christmas issue of The BMJ. Sanne van Dijk and colleagues call on Disney to consider strategies such as mindfulness and personal protection measures to improve princesses’ wellbeing and help them start living healthily ever after.  Snow White is the “fairest princess of all” yet as a scullery maid for her wicked stepmother, opportunities for social interaction are extremely limited, putting her at risk of cardiovascular disease, depression, anxiety, and early death, explain the authors. Fortunately, Snow White meets the Seven ...

Coaching trainees just before a procedure could improve patient safety

2024-12-17
Giving inexperienced clinicians a quick coaching session with an expert just before they carry out a procedure boosts their success rate and could improve patient safety, finds a study in the Christmas issue of The BMJ. Athletes and musicians often rehearse, warm up, or practice just before they are about to perform. Yet in medicine, where performing a procedure can have life-altering consequences, warm-up, or “just-in-time” training is rare to non-existent.  To fill this knowledge gap, a team of US researchers conducted a randomised clinical trial to assess whether coaching inexperienced clinicians just before intubating an infant (inserting ...

Mass General Brigham study finds lower rates of death from Alzheimer’s disease among taxi and ambulance drivers

2024-12-17
A new study raises the possibility that jobs that require frequent spatial processing—such as figuring out a taxi route or the best way to navigate to a hospital—could lead to lower rates of death from Alzheimer’s disease. Researchers from Mass General Brigham investigated this possibility by using national data on the occupations of people who had died to evaluate risk of death from Alzheimer’s disease across 443 professions. They found that taxi driving and ambulance driving were associated with a lower rate of death from Alzheimer’s disease compared to other professions. Results ...

Towards quantitative point-of-care testing with novel bioluminescent immunosensor

Towards quantitative point-of-care testing with novel bioluminescent immunosensor
2024-12-17
A novel nanobody-based immunosensor, designed to function stably in undiluted biological fluids and harsh conditions, has been developed, as reported by researchers from Science Tokyo. Their innovative design leverages BRET—bioluminescence resonance energy transfer—and exhibits great potential for point-of-care testing, therapeutic drug monitoring, and environmental applications using paper-based devices. Immunosensors have become indispensable tools in the fields of biochemistry and medical science, providing reliable methods for detecting specific biomolecules. They work by exploiting the interactions between antibodies ...

Health and wellbeing should be at the centre of housing strategy to save lives

2024-12-17
A ground-breaking new report by the UCL Institute of Health Equity (IHE) published today, Tuesday 17 December, highlights the profound impacts – both positive and negative – that housing has on health and wellbeing. Building Health Equity: The Role of the Property Sector in Improving Health lays out how poor quality and inequitable access to homes that people can afford is linked with worse mental and physical health, whereas increased availability of secure, affordable, warm homes can improve long-term health and longevity. The IHE’s report, which has been sponsored by Legal and General, proposes a new way forward to enable the property sector and national and local ...

Transcendental Meditation most effective at treating PTSD in largest review to date

Transcendental Meditation most effective at treating PTSD in largest review to date
2024-12-16
A Groundbreaking Comparison of Meditation Techniques Researchers from Maharishi International University (MIU) and Augusta University have conducted the largest review and meta-analysis to date on meditation for PTSD treatment. Analyzing 61 studies with over 3,400 participants, the study compared four categories of meditation: Mindfulness-Based Stress Reduction (MBSR), Mindfulness-Based Other techniques (MBO), Other Meditations (OM), and Transcendental Meditation (TM). Effect sizes for the first three categories ...

NYU Tandon researchers create microchips capable of detecting and diagnosing diseases

2024-12-16
In a world grappling with a multitude of health threats — ranging from fast-spreading viruses to chronic diseases and drug-resistant bacteria — the need for quick, reliable, and easy-to-use home diagnostic tests has never been greater. Imagine a future where these tests can be done anywhere, by anyone, using a device as small and portable as your smartwatch. To do that, you need microchips capable of detecting miniscule concentrations of viruses or bacteria in the air.  Now, new research from NYU Tandon faculty including Professor of Electrical and Computer Engineering Davood Shahrjerdi; Herman ...

15 million U.S. adults are at elevated risk for heart failure

2024-12-16
Embargoed for release until 5:00 p.m. ET on Monday 16 December 2024     @Annalsofim          Below please find summaries of new articles that will be published in the next issue of Annals of Internal Medicine. The summaries are not intended to substitute for the full articles as a source of information. This information is under strict embargo and by taking it into possession, media representatives are committing to the terms of the embargo not only on their own behalf, but also on behalf of the organization they represent.     ...

Tiny ancient worm sheds big light on evolution mystery

Tiny ancient worm sheds big light on evolution mystery
2024-12-16
A groundbreaking fossil discovery in remote South Australia sheds light on one of evolution’s greatest mysteries: the origins of Ecdysozoa, a superphylum of molting animals including insects, crustaceans, and nematodes. Ecdysozoans are the largest, most species-rich animal group on Earth. Although more than half of all animals are ecdysozoans, scientists have long grappled with the lack of evidence of ecdysozoan ancestors in the fossil record, despite molecular evidence suggesting they should exist in the Precambrian. Now, in a new study published in Current ...

Study examines how culture, family and identity shape body image challenges for Hispanic women

2024-12-16
LAWRENCE, KANSAS — While culture is intertwined with values surrounding food and body image, cultural differences have historically been overlooked by researchers and clinicians seeking to identify and treat eating disorders.  The lack of culturally relevant approaches has been huge barrier for Hispanic, or Latine, women in accessing care, said Sarah Johnson-Munguia, a sixth-year University of Kansas graduate student working in Center for the Advancement of Research on Eating Behaviors (CARE) Lab at the KU Life Span Institute.  Johnson-Munguia is the lead author of a paper published in ...

Study explores whether CBD can reduce scan-related anxiety in patients with advanced breast cancer

2024-12-16
The findings showed that CBD did not significantly change scan-related anxiety when compared to a placebo, but researchers did find that CBD was safe and resulted in significantly lower overall anxiety levels Anxiety is extremely common among adults receiving cancer care, with as many as one out of every four patients meeting the clinical criteria for anxiety. Many patients with cancer also experience scan-related anxiety (scanxiety), a condition in which individuals develop anxiety related to getting imaging ...

New paper examines the elusive nature of liquid brines on Mars

New paper examines the elusive nature of liquid brines on Mars
2024-12-16
More than a hundred years ago, astronomer Percival Lowell made the case for the existence of canals on Mars designed to redistribute water from the Martian ice caps to its lower, drier latitudes. This necessarily meant the existence of Martians to build the canals. While Lowell was proven wrong by better telescopes, the question of whether there’s liquid water on Mars continues to tantalize researchers. Liquid water is a critical precondition for a habitable planet. Yet the combination of low temperature, atmospheric pressure and water vapor pressure on Mars means any liquid water found there would ...

Threat of abrupt mortality events keeps endangered monkey population at risk, despite decades of growth

Threat of abrupt mortality events keeps endangered monkey population at risk, despite decades of growth
2024-12-16
Despite the population being almost four times larger than it was in 1982, a new study published in the journal Ecology suggests the northern muriqui monkeys remain at risk, especially in the face of ongoing habitat disturbances. Northern muriquis, which live in the Atlantic Forest of Brazil, are much more peaceful and egalitarian compared to other primates. They are also one of the most endangered species of monkey in the world. Karen Strier, a professor of anthropology at UW–Madison and lead author of the paper, has spent 40 years studying the behavior and ecology of these monkeys in a small, preserved portion ...
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