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Psilocybin shows context-dependent effects on social behavior and inflammation in female mice modeling anorexia

2026-02-03
CLAYTON, Victoria, AUSTRALIA, 3 February 2026 -- Researchers led by Dr. Claire Foldi at Monash University have discovered that psilocybin, the psychoactive compound found in magic mushrooms, produces subtle but distinct effects on social behavior and inflammation that depend critically on metabolic and exercise context in female mice. The peer-reviewed study, published in Psychedelics, represents the first systematic investigation of how this compound influences sociability in female mice exposed to activity-based anorexia (ABA), a widely ...

Mental health crisis: Global surveys expose who falls through the cracks and how to catch them

2026-02-03
NEWTON, Massachusetts, USA, 3 February 2026 -- In a comprehensive Genomic Press Interview published today in Genomic Psychiatry, Dr. Ronald C. Kessler, the McNeil Family Professor of Health Care Policy at Harvard Medical School, reflects on a career that fundamentally altered how researchers and policymakers across the globe understand the prevalence, distribution, and treatment of mental disorders. With secondary appointments as Professor of Epidemiology at the Harvard T.H. Chan School of Public Health, Program Director at the University of Michigan Institute for Social Research, and at the Massachusetts General Hospital Center for Precision Psychiatry, Dr. Kessler has built an unparalleled ...

New boron compounds pave the way for easier drug development

2026-02-03
A major step towards simpler drug development has been taken at the University of Gothenburg. In a new study, researchers have developed stable boron-fluorine compounds that make it possible to increase the effect or reduce side effects without breaking down the medicine. Chemical compounds based on the element boron are central tools in modern chemistry and are used, among other things, to build drugs, advanced materials, and molecules for medical diagnostics. Some types of boron compounds are still difficult to produce, especially when the boron atom must be placed very precisely in a complex molecule. This limits the possibilities for ...

Are cats ‘vegan’ meat eaters? Study finds why isotopic fingerprint of cat fur could trick us into thinking that way

2026-02-03
Cats – unlike humans – are true carnivores: they must eat meat to survive because their bodies can’t draw some essential nutrients from plants. By looking at tissues, researchers can get a good understanding of what foods animals ate. Now, researchers at the Department of Microbiology and Ecosystem Science at the University of Vienna measured nitrogen and its stable isotopes 15N and 14N in the fur and whiskers of domestic cats as well as in cat food available in supermarkets. They then compared nitrogen isotope values to those found in the hair of humans ...

Unexpected partial recovery of natural vision observed after intracortical microstimulation in a blind patient

2026-02-03
A patient with complete blindness caused by irreversible optic nerve damage partially recovered natural vision after participating in a clinical trial of electrical stimulation of the visual cortex conducted by researchers from the Universidad Miguel Hernández de Elche (UMH) and the CIBER in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN). The unexpected improvement was spontaneous, sustained over time, and independent of the implanted device. The case was observed during a study designed to evaluate the safety and feasibility of a cortical visual prosthesis. Although the goal of the trial was to generate artificial visual ...

From sea to soil: Molecular changes suggest how algae evolved into plants

2026-02-03
Before plants evolved, vegetative life consisted of primitive green algae living in the sea. Like plants, these algae survived by performing photosynthesis, turning sunlight into energy. However, little light reaches the ocean where algae live; therefore, they evolved specialized organs to grab what little is available. Among these tiny ocean algae are prasinophytes, which are among the earliest photosynthetic life forms on Earth. Like all photosynthetic organisms, they rely on a pigment–protein complex called LHC to capture sunlight. How efficiently LHC performs photosynthesis in different environments depends on the pigments ...

Landmark study to explore whether noise levels in nurseries affect babies’ language development

2026-02-03
Nearly two million children in the UK are affected by early language delays. New research will examine whether noise in nurseries is a hidden factor.  An estimated 1.9 million children across the UK are affected by early language delays, with rates doubling among children from disadvantaged backgrounds. A major new research project led by The Institute for the Science of Early Years (ISEY) at the University of East London supported by the Nuffield Foundation, will explore how background noise in nurseries affects early language development. The study ...

Everyday diabetes medicine could treat common cause of blindness

2026-02-03
Doctors have found that metformin, an everyday medicine for diabetes, is associated with less progression of age-related macular degeneration (AMD), the commonest cause of blindness in western countries. People with diabetes over the age of 55 years taking metformin were 37% less likely to develop the intermediate stage of AMD over a five year period compared to those not taking metformin. AMD is a disease which affects the central retina or macular at the back of the eye. It eventually causes the light-sensitive tissue to die off (geographic atrophy, a form of ‘dry’ ...

Ultra-thin metasurface chip turns invisible infrared light into steerable visible beams

2026-02-03
New York, February 2, 2026 — The invention of tiny devices capable of precisely controlling the direction and behavior of light is essential to the development of advance technologies. Researchers at the Advanced Science Research Center at the CUNY Graduate Center (CUNY ASRC) have taken a significant step forward with the developed of a metasurface that can turn invisible infrared light into visible light and aim it in different directions—without any moving parts. The details of their work are explained in a new paper published in the journal eLight. The novel metasurface is constructed of an ultra-thin chip patterned with ...

Cluster radioactivity in extreme laser fields: A theoretical exploration

2026-02-03
From Laser Breakthroughs to New Frontiers in Nuclear Decay Control With the continuous progress in experimental laser technology, significant improvements in laser energy and peak intensity have been achieved in recent years. The direct interaction between intense lasers and atomic nuclei has emerged as an exciting new possibility, one capable of altering nuclear decay lifetimes. Investigating the influence of strong laser fields on nuclear decay can elucidate how these fields affect nuclear structure ...

Study finds banning energy disconnections shouldn’t destabilise markets

2026-02-03
Approaches by some European countries and Australia to protect energy consumers could help countries worldwide phase out harmful electricity disconnections without destabilising power markets, new research has found. The RMIT University-led study examines protections in Spain, France and Ireland and outlines how similar measures could be adapted in other competitive energy markets to reduce the harms caused by disconnections for non‑payment. Across Europe, 20 million households were disconnected from electricity and gas at some point during 2022, according to the EU Agency for the Cooperation ...

Researchers identify novel RNA linked to cancer patient survival

2026-02-02
In a recent study published in the Proceedings of the National Academy of Sciences (PNAS), researchers at the Texas A&M University Health Science Center (Texas A&M Health) identify a novel RNA molecule that plays a crucial role in preserving the integrity of a key cellular structure, nucleolus (a dense region of the cell containing a subset of crucial genetic material). Their findings also suggest this molecule may influence patient survival in certain blood cancers. A surprising discovery inside a familiar gene RNA, or ribonucleic acid, is a short-lived molecule copied from DNA that enables cells to use genetic information. Specific DNA ...

Poverty intervention program in Bangladesh may reinforce gender gaps, study shows

2026-02-02
URBANA, Ill.  – In Bangladesh, programs targeting ultra-poor, rural households can help families escape extreme poverty. However, the programs may have the unintended consequence of reinforcing gender gaps, a new study from the University of Illinois Urbana-Champaign finds. “We were interested in looking at whether such interventions influence parents’ expectations for their children’s education and occupation, which can promote social mobility. Because there are huge disparities between boys and girls in Bangladesh, we also wanted to see if it affected the gender gap,” said lead author Alejandro Montoya Castaño. He was a doctoral ...

Novel approach to a key biofuel production step captures an elusive energy source

2026-02-02
Plants grown for biofuel have the potential to power our travel industry, but an important fraction of their chemical power has remained stubbornly difficult to recover. New research from the DOE-funded Center for Advanced Biofuel and Bioproduct Innovation on the University of Illinois campus has demonstrated a way to preserve native lignin structure, a key component of plant matter for conversion to other valuable products, putting an improved pathway for biofuel and bioproduct production within reach. The ...

‘Ghost’ providers hinder access to health care for Medicaid patients

2026-02-02
Almost one-third of physicians who are enrolled in Medicaid don’t actually care for a single patient covered by Medicaid insurance, according to new research led by Oregon Health & Science University. The study, published today in the journal Health Affairs, sheds new light on a program that covers nearly 80 million Americans. Researchers also found that another third of health care providers enrolled in Medicaid see a high volume of patients — more than 150 annually — and may be overburdened. Combined, the findings paint a picture of a situation in which enrollment data alone may obscure the reality ...

Study suggests far fewer cervical cancer screenings are needed for HPV‑vaccinated women

2026-02-02
Embargoed for release until 5:00 p.m. ET on Monday 2 February 2026    Follow @Annalsofim on X, Facebook, Instagram, Bluesky, and Linkedin              Below please find summaries of new articles that will be published in the next issue of Annals of Internal Medicine. The summaries are not intended to substitute for the full articles as a source of information. This information is under strict embargo and by taking it into possession, media representatives are committing to the terms of the embargo not only on their own behalf, but also on ...

NUS CDE researchers develop new AI approach that keeps long-term climate simulations stable and accurate

2026-02-02
Hybrid climate modelling has emerged as an effective way to reduce the computational costs associated with cloud-resolving models while retaining their accuracy. The approach retains physics-based models to simulate large-scale atmospheric dynamics, while harnessing deep learning to emulate cloud and convection processes that are too small to be resolved directly. In practice, however, many hybrid AI-physics models are unreliable. When simulations extend over months or years, small errors can accumulate and cause the model to become unstable. In a new ...

UM School of Medicine launches clinical trial of investigative nasal spray medicine to prevent illnesses from respiratory viruses

2026-02-02
Last year, at least one million people in the U.S. were hospitalized for respiratory virus illnesses like the flu or COVID-19, according to the Centers for Disease Control and Prevention. Many of these individuals were at higher risk of getting infections due to living or working around young children who contract more respiratory infections. A new clinical trial led by researchers at the University of Maryland School of Medicine’s (UMSOM) Center for Vaccine Development and Global Health (CVD) will test a new experimental intranasal ...

Research spotlight: Use of glucose-lowering SGLT2i drugs may help patients with gout and diabetes take fewer medications

2026-02-02
Natalie McCormick, PhD, of the Rheumatology and Allergy Clinical Epidemiology Research (RACER) Center within the Division of Rheumatology in the Mass General Brigham Department of Medicine, is the lead author of a paper published in Diabetes Care, “Gout-Related Medication Use After Initiating Sodium–Glucose Cotransporter 2 Inhibitors in Patients With Gout and Type 2 Diabetes: Population-Based Target Trial Emulation Studies.” Q: What challenges or unmet needs make this study important? Gout, a type of inflammatory arthritis caused by a buildup of uric acid (urate) in the body, affects 5.1% ...

Genetic system makes worker cells more resilient producers of nanostructures for advanced sensing, therapeutics

2026-02-02
Gas vesicles are among the largest known protein nanostructures produced and assembled inside microbial cells. These hollow, air-filled cylindrical nanostructures found in certain aquatic microbes have drawn increasing interest from scientists due to their potential for practical applications, including as part of novel diagnostic and therapeutic tools. However, producing gas vesicles is a hard ask for cells in the lab, hindering the development of applications. In a recent study published in Nature Communications, a team of researchers led by Rice University bioengineer George Lu reports the development of a new genetic regulatory system to improve cell viability during the production ...

New AI model can assist with early warning for coral bleaching risk

2026-02-02
MIAMI — Scientists have created an AI model that forecasts moderate heat stress — a major precursor to coral bleaching — at sites along Florida’s Coral Reef up to six weeks ahead, with predictions generally accurate within one week. The study presents a site-specific, explainable machine-learning framework to support coral scientists and restoration practitioners with local reef management and emergency response planning. “This model gives coral scientists and resource managers advance notice of whether heat stress is likely to occur in a season — and, more importantly, ...

Highly selective asymmetric 1,6-addition of aliphatic Grignard reagents to α,β,γ,δ-unsaturated carbonyl compounds

2026-02-02
Scientists at Institute of Science Tokyo (Science Tokyo) have successfully realized the highly selective asymmetric 1,6-addition of aliphatic Grignard reagents to α,β,γ,δ-unsaturated carbonyl compounds. This new methodology employs an iron catalyst in combination with a chiral N-heterocyclic carbene ligand, which suppresses undesired side reactions and drives highly regio-, stereo-, and enantioselective alkyl migration. The achievement represents a major advance in organic synthesis, offering new opportunities for drug discovery, materials chemistry, and the fine-chemical sector.   In organic chemistry, ...

Black and Latino teens show strong digital literacy

2026-02-02
A study by UC Riverside and USC education scholars found that Black and Latino teens are significantly more adept than their white peers at detecting online disinformation—particularly content related to race and ethnicity. These youth are not only quicker to identify false claims and racist propaganda, but also more likely to verify posts with credible sources and respond with corrective, fact-based content,      the study found. According to the researchers, these skills are not being taught.  “This ...

Aging brains pile up damaged proteins

2026-02-02
As we age, we begin to lose the connections that wire up our brains—and neuroscientists aren’t sure why.  It is increasingly clear, though, that the loss of synapses—the flexible and adaptive relay stations central to our brains’ ability to think, learn, and remember—is central to the rise of cognitive decline and dementia in old age. Now, researchers supported by the Knight Initiative for Brain Resilience have discovered clues that may tie synapse loss to another hallmark of brain aging: the declining ability of brain cells to break down and recycle damaged proteins. Published January 21, 2026, in Nature, the study shows ...

Optimizing robotic joints

2026-02-02
Key Takeaways Harvard SEAS researchers have developed a mathematical framework for optimizing the design of rolling contact joints, which are made of rolling surfaces and flexible connectors. To demonstrate their method, they developed a knee-like joint that reduced misalignment by 99% compared with standard mechanisms, and a robotic gripper that could hold three times the weight of a conventionally designed gripper.  Consider the marvelous physics of the human knee. The largest hinge joint in the body, it has two rounded bones held together ...
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