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Toward a cervical cancer–free future: Cancer Biology & Medicine highlights science, policy, and equity

2025-11-20
Cervical cancer will be the first human cancer eliminated through coordinated global action. A new special issue of Cancer Biology & Medicine brings together leading experts from around the world to examine progress, challenges, and innovations in prevention, screening, and treatment. From policy frameworks and epidemiological insights to digital health tools and therapeutic vaccines, the collection provides a timely resource for accelerating the World Health Organization’s 2030 targets for cervical cancer elimination and advancing ...

Population-specific genetic risk scores advance precision medicine for Han Chinese populations

2025-11-20
Researchers at Academia Sinica have developed the first population-specific polygenic risk score (PRS) models for people of Han Chinese ancestry, achieving unprecedented accuracy in predicting risks for common diseases such as diabetes, heart disease, autoimmune disorders. The study, published in Nature on October 15,2025, analyzed genomic and health data from more than half a million Taiwanese participants of the Taiwan Precision Medicine Initiative (TPMI) and demonstrates the transformative potential ...

For young children, finger-counting a stepping stone to higher math skills

2025-11-20
Children who count on their fingers between ages 4 and 6 1/2 have better addition skills by age 7 than those who don’t use their fingers, suggesting that finger counting is an important stepping stone to higher math skills, according to research published by the American Psychological Association. “Finger counting is not just a tool for immediate success in young children, but a way to support the development of advanced abstract arithmetic skills,” said lead author Catherine Thevenot, PhD, of the University of Lausanne in Switzerland. Finger counting is widely used by young children as a strategy to solve math problems. However, ...

Mayo Clinic physicians map patients’ brain waves to personalize epilepsy treatment

2025-11-20
ROCHESTER, Minn. — Mayo Clinic researchers have developed a new, personalized approach to deep brain stimulation (DBS) for people with drug-resistant epilepsy. By mapping each patient's unique brain wave patterns, the method allows physicians to target the precise area in the brain where stimulation is most effective, moving beyond the traditional one-size-fits-all approach. DBS involves implanting electrodes in the brain to deliver electrical pulses that help prevent and control seizures. While effective, DBS is typically administered with electrodes placed in the same brain region across most patients. Mayo Clinic physician-scientists ...

Global Virus Network awards pandemic preparedness grants to advance global surveillance and early detection of viral threats

2025-11-20
Tampa, FL, USA – November 20, 2025 – The Global Virus Network (GVN) is pleased to announce that, for the first time, it is awarding pandemic preparedness research grants, totaling $160,000, to GVN scientists across four continents. These awards support innovative, investigator-led projects designed to enhance viral surveillance, early detection, and scientific preparedness, particularly in regions vulnerable to emerging and re-emerging viral threats. “These projects represent exactly the kind of targeted, ...

Ginkgo Datapoints launches the Virtual Cell Pharmacology Initiative to build a community-driven data standard for AI drug discovery

2025-11-20
BOSTON — Nov. 20, 2025 — Ginkgo Bioworks (NYSE: DNA) today announced the launch of the Virtual Cell Pharmacology Initiative (VCPI) through Ginkgo Datapoints. This open-source platform is designed to build the first standardized framework for virtual cell modeling in drug discovery by bringing together researchers, pharmaceutical companies and AI developers in a community-driven effort to create the largest public dataset of its kind, aiming to test at least 100,000 compounds and generate >12 billion data points. Virtual cells, AI-powered digital representations of biological cells, are emerging as a critical ...

Cleveland’s famous sea monster gets a scientific update

2025-11-20
CLEVELAND—About 360 million years ago, the shallow sea above present-day Cleveland was home to a fearsome apex predator: Dunkleosteus terrelli. This 14-foot armored fish ruled the Late Devonian seas with razor-sharp bone blades instead of teeth, making it among the largest and most ferocious arthrodires—an extinct group of shark-like fishes covered in bony armor across their head and torso. Since its discovery in the 1860s, Dunkleosteus has captivated scientists and the public alike, becoming ...

University of Minnesota chemists pioneer new method for future drug and agrochemical discovery

2025-11-20
MINNEAPOLIS / ST. PAUL (11/20/2025) — A team of organic and computational chemists at the University of Minnesota Twin Cities have created a new, modern tool to make the process of creating pharmaceuticals and agrochemicals faster, cost-effective, and energy-efficient. The research, recently published in Nature, details a new method for creating the essential starting materials, known as precursors, used in chemical reactions. A patent is pending for this technique. Chemists use what are called “aryne intermediates” as building blocks to make complex molecules more efficiently in areas such as pharmaceuticals ...

Will my kid be a pro athlete? Study finds what parents think

2025-11-20
COLUMBUS, Ohio – Many children grow up dreaming – or maybe even expecting – that they will become a star in football, basketball or whatever their favorite sport may be.   Most parents have more realistic expectations of their children’s future athletic achievement, a new study finds. But a substantial minority believe their kids will beat the odds and become collegiate, pro or even Olympic athletes.   In a survey of 785 American parents, 34% thought it was somewhat or very likely that their child would become a small-college athlete, 27% thought it was likely they would become a college scholarship athlete, and 17% thought it was somewhat ...

23andMe Research Institute helps reconnect African diaspora to their roots with release of 250+ high-resolution African Genetic Groups

2025-11-20
PALO ALTO, Calif. - November 20, 2025 - For millions of Americans in the African diaspora, genealogical ties and records were severed by the transatlantic slave trade, creating a "brick wall" for those seeking to know their full heritage. Today, 23andMe Research Institute announced a landmark expansion of its genetic ancestry reports and features, unveiling more than 250 high-resolution Genetic Groups across Africa. This significant update provides members with African heritage the most detailed and scientifically ...

Isotope-based method for detecting unknown selenium compounds

2025-11-20
Although present in very small amounts, selenium (Se)-based compounds play important roles in protecting the body from oxidative stress, regulating thyroid hormones, strengthening the immune system, and even detoxifying heavy metals. As we begin to understand more about the biological functions of Se, the need to detect and identify Se-containing compounds has become increasingly important. Researchers from Chiba University, Japan, have developed a new method that selectively detects Se compounds, addressing a long-standing challenge in the identification of unknown Se-containing compounds. Using a previously unexplored approach, the researchers discovered novel Se-containing molecules in ...

Daily oral GLP-1 pill exhibits promising results in treatment options for adults with diabetes and obesity in trial led by UTHealth Houston researcher

2025-11-20
A new oral GLP-1 medication can help adults with obesity and Type 2 diabetes lose more weight and improve their blood sugar levels compared to a placebo, according to findings from the ATTAIN-2 trial led by a UTHealth Houston researcher. Obesity is a chronic health condition that can cause serious complications such as Type 2 diabetes, heart disease, high blood pressure, sleep apnea, certain cancers, and more. Current GLP-1 treatments for obesity consist of daily or weekly injectable medications that come with drawbacks, including the need for cold chain ...

The road ahead: Why conserving the invisible 99% of life is fundamental to planetary health

2025-11-20
A new paper outlines how scientists came together to put together the first microbial conservation roadmap under the leadership of Applied Microbiology International President, Professor Jack Gilbert. The article, ‘Safeguarding Microbial Biodiversity: Microbial Conservation Specialist Group (MCSG) within the Species Survival Commission of the International Union for Conservation of Nature (IUCN)' is published in Sustainable Microbiology, an AMI journal. In July 2025, IUCN formally launched the MCSG within its Species Survival Commission, co-chaired by Professor Gilbert and Raquel Peixoto (KAUST / ISME). This came out of a meeting ...

Dopamine signaling in fruit flies lends new insight into human motivation

2025-11-20
Our brain’s reward system processes and reinforces pleasurable experiences, motivating us to seek out and engage in rewarding activities ranging from eating to social interactions to recreational drug use. Dopamine plays an important role in this process, mediated by the D2 dopamine receptor (D2R). New research published today in Nature Neuroscience finds that the same mechanism that causes drug addiction (desensitization of D2R) also controls the natural devaluation of repeated behaviors (e.g. seeking out the same thrill of going on a rollercoaster for the first time). This is the first natural use found for this mechanism. Researchers from ...

American Gastroenterological Association streamlines Crohn’s disease treatment guidance as new therapies expand options

2025-11-20
Bethesda, MD (Nov. 17, 2025) — The American Gastroenterological Association (AGA) has released a comprehensively updated clinical guideline on the pharmacological management of moderate-to-severe Crohn’s disease. The new guideline uses cutting-edge network meta-analyses to recommend prescribing medications based on patients’ prior treatments for moderate-to-severe Crohn’s disease.  The guideline organizes treatments by efficacy to simplify decision-making for gastroenterologists and over 3 million people worldwide living with Crohn’s disease. This living guideline reflects the rapid pace of innovation in medical ...

New ‘sensor’ lets researchers watch DNA repair in real time

2025-11-20
Cancer research, drug safety testing and ageing biology may all gain a major boost from a new fluorescent sensor developed at Utrecht University. This new tool allows scientists to watch DNA damage and repair unfold in real time inside living cells. The development, which opens the door to experiments that weren’t feasible before, is published today in the journal Nature Communications. DNA inside our cells is constantly damaged by sunlight, chemicals, radiation or simply by the many processes that keep us alive. Usually, the cell fixes this damage quickly and efficiently. But when repair fails, the consequences can be serious, contributing ...

Customized cells to fight brain cancer

2025-11-20
With a five-year survival rate of less than 5%, glioblastoma is one of the most aggressive types of brain cancer. Until now, all available treatments, including immunotherapy — which involves strengthening the immune system to fight cancer— have proved disappointing. CAR-T cells are genetically modified immune cells manufactured in the laboratory and designed to identify and destroy cancer cells. By targeting a protein present in the tumour environment, a team from the University of Geneva (UNIGE) and ...

How superstorm Gannon squeezed Earth’s plasmasphere to one-fifth its size

2025-11-20
A geomagnetic superstorm is an extreme space weather event that occurs when the Sun releases massive amounts of energy and charged particles toward Earth. These storms are rare, occurring about once every 20-25 years. On May 10-11, 2024, the strongest superstorm in over 20 years, known as the Gannon storm or Mother’s Day storm, struck Earth.   A study led by Dr. Atsuki Shinbori from Nagoya University's Institute for Space-Earth Environmental Research has captured direct measurements of this extreme event and provided the ...

Gene scissors in camouflage mode help in the search for cancer therapies

2025-11-20
The immune system plays a crucial role in fighting tumours and metastases. Consequently, it is decisive to conduct cancer research in mouse models with an immune system that is as natural as possible – which is easier said than done. Thanks to CRISPR/Cas9 technology, researchers can quickly create a pool of hundreds of tumour cells, each with a different gene switched off. When transplanted into mice, it becomes apparent which of these silenced genes influences the development and spread of cancer. Assisted by such CRISPR screens, scientists are able to identify valuable approaches for the development of new therapies. But the method comes with a catch. The components of ...

Breaking the cycle of vulnerability: study identifies modifiable elements to build community resilience and improve health

2025-11-20
November 20, 2025 - A novel study empirically linking a standardized measure of community resilience in more than 3,100 U.S. counties to cognitive, mental, and physical health outcomes shows that counties with fewer healthcare resources, limited digital tools, and weaker support systems exhibit poorer overall health among their residents. The article appearing in the American Journal of Preventive Medicine, published by Elsevier, indicates that resilience can be measured, strengthened, and designed into our systems of care using modifiable tools like healthcare access, support networks, and technology. Resilience ...

Millions of people in the UK are being drawn into bribery and money laundering, according to new study

2025-11-20
Bribery and money laundering are far more common among the public than many assume, with millions of people in the UK approached to take part in these activities in the past year, according to a new report co-authored by a researcher from the University of Surrey on behalf of the International Society of Economic Criminology (ISEC).  The report found that 16% of UK adults had been asked for a bribe in the last 12 months and 11% (5.8 million UK adults per year) had been asked to help move money that ...

Could a child have painted that? Jackson Pollock's famous pour-painting has child-like characteristics, study shows

2025-11-20
What makes art art? Is it the method or the creator? Does it need a color palette and oil paints, or a canvas laid flat on the floor and paint splattered across it? Does it require a critically acclaimed painter, or a toddler with crayons? And when it comes to the artist, can we even reliably tell if an artwork has been created by children or adults? In a new Frontiers in Physics study, researchers in the US put it to the test. “Our study shows that the artistic patterns generated by children are distinguishable from those created by adults ...

Broad support for lethal control of wild deer among nature organisation subscribers

2025-11-20
Embargo: 20th November 2025 at 05:01 UK time Broad support for lethal control of wild deer among nature organisation subscribers There is broad support for regulated lethal control of wild deer to reduce their numbers and impacts among subscribers of nature organisations in England and Wales, a new study has found. According to research led by Bangor University and published in People and Nature, it was the most supported and widely used deer management practice. The authors of the study believe that the findings might help nature organisations and decision makers feel more confident about recommending its use. Researchers ...

Over a decade in the making: Illuminating new possibilities with lanthanide nanocrystals

2025-11-20
In a discovery shaped by more than a decade of steady, incremental effort rather than a dramatic breakthrough, scientists from the National University of Singapore (NUS) and their collaborators demonstrated that great ideas flourish when paired with patience. Flashback to 2011: a small group of young researchers gathered around an aging optical bench at the NUS Department of Chemistry, watching a faint, flickering glow on a screen. Their goal seemed deceptively simple: make an insulating crystal emit light when electricity flowed through it. The challenge, however, was nearly impossible. Lanthanide nanocrystals, known for their chemical stability and ...

Deadly, record-breaking heatwaves will persist for 1,000 years, even under net zero

2025-11-20
Deadly hotter and longer heatwaves, which worsen in severity the longer it takes to reach net zero carbon emissions, will become the norm predicts new climate research. Published in Environmental Research: Climate, researchers at the ARC Centre of Excellence for 21st Century Weather and CSIRO used climate modelling and supercomputers to understand how heatwaves will respond over the next 1,000 years, after the world reaches net zero carbon emissions. They chose a range of dates between 2030 and 2060 and calculated the long-term difference in heatwaves for each ...
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