The SuperCDMS experiment at SNOLAB in Ontario has reached its operating temperature - hundreds of times colder than outer space - marking the transition from construction to active science as researchers prepare to search for lightweight dark matter particles.

A UC San Diego-led team demonstrated that acoustic waves can controllably move mechanical kinks - boundaries between soft and stiff regions - through a specially designed material, creating what amounts to remote control over how a material feels and behaves.

A new data platform harmonizes nearly 10 million electronic health records across three U.S. health systems to study how multiple chronic diseases, behaviors, and social factors interact over time to shape Alzheimer's risk - moving beyond single-disease models of dementia.

Nearly half the world carries H. pylori, a bacterium linked to stomach cancer. TUM researchers found that metronidazole targets two key protective proteins, then created a chemical variant 60 times more potent that also cleared infection in mice at very low doses while preserving gut bacteria.

A quick nasal swab collected living nerve and immune cells whose gene activity patterns separated early and clinical Alzheimer's from healthy controls with 81% accuracy - potentially catching the disease before symptoms appear, when new treatments may work best.

University of Pennsylvania engineers created a lipid nanoparticle that simultaneously blocks the immune-suppressing enzyme IDO and delivers mRNA for the immune activator IL-12. In mice, the approach eliminated established colon tumors, prevented recurrence, and triggered body-wide anti-tumor immunity.

MIT neuroscientists found that mice with a mutation in grin2a - a gene linked to schizophrenia in large human studies - are significantly slower to adapt their decisions when reward conditions change, due to impaired signaling in a thalamus-to-cortex circuit.

Protein sequencing has lagged far behind DNA sequencing in speed and scale. Stanford bioengineers developed a chemistry that converts protein sequences into DNA barcodes, potentially seeing 1,000 times more molecules than mass spectrometry from the same sample.

University of Konstanz physicists built a system where two magnetic layers generate friction without ever touching. The friction peaks at intermediate distances rather than increasing steadily with load, violating Amontons' law - one of the oldest rules in physics.

Less than 2% of nitrile rubber gets recycled. Chemists at St Andrews developed two catalytic routes that convert used nitrile gloves into polyamines and polyols - useful industrial chemicals - with the polyamines also capable of capturing carbon dioxide from emissions.

When HER2-positive breast cancer spreads to the fluid surrounding the brain, patients typically survive less than five months. A new Phase II trial from MD Anderson found a three-drug regimen more than doubled median survival to 10 months, with 41% of patients alive at 18 months.

A cold freshwater layer beneath Antarctic sea ice had shielded it from warm deep water for decades. University of Gothenburg researchers show that layer thinned gradually, then collapsed during fierce 2015 storms, triggering rapid ice loss that persists today.

A comprehensive carbon budget from a Swiss stream corridor shows beaver-engineered wetlands accumulated 1,194 tonnes of carbon over 13 years - storing CO2 at rates up to ten times higher than comparable systems without beavers, while methane emissions accounted for less than 0.1% of the total budget.

Scientists measured mid-infrared reflectance in bird feathers for the first time, finding that visually identical ravens absorb heat differently by subspecies, while open-habitat bobwhites show the most variation in thermal emittance - suggesting feathers evolve for heat management invisible to the eye.

Entomologists have formally described Andrena cenizophila, a mining bee from southwest Texas and northern Mexico that collects pollen exclusively from cenizo (Texas purple sage) during its brief, rain-triggered blooms - making it the only known mining bee specialized on this shrub.

Researchers at King's College London and the University of Surrey developed a method to select and chemically analyze single human cells infected with TB-model bacteria, revealing metabolic differences between infected and uninfected macrophages invisible to conventional bulk analysis.

With two-thirds of workers reporting burnout, psychologist Shaina Siber's new framework integrates Acceptance and Commitment Therapy (ACT) and Compassion-Focused Therapy (CFT) to target the brain changes that make self-care approaches insufficient for recovery.

Scientists at the Helmholtz Centre found a three-species bacterial consortium that degrades multiple phthalate ester plasticizers through cross-feeding, a cooperative metabolic strategy not previously documented in plastic-eating microbes, using enzymes new to science.

In a study of more than 7,800 postmenopausal women, higher scores on the American Heart Association's cardiovascular health metrics were linked to lower all-cause and cardiovascular mortality, with adiposity and systemic inflammation partially mediating the association.

By shaping a near-infrared laser pulse into a steep-rise, slow-decay waveform, researchers achieved tip-enhanced sum frequency generation spectroscopy that suppresses metallic background noise and detects weak vibrational signals with a 10-million-fold enhancement factor.

Researchers at Xiamen University and Imperial College London developed a computational tool that predicts real supercapacitor device energy density from early material tests with less than 1% error, revealing a conversion factor of roughly 0.35 between material and device performance.

Researchers have developed a one-step laser technique that creates prelithiated silicon-graphene battery anodes at room atmosphere, delivering over 1700 mAh/g capacity with 83% retention after 4,500 charge cycles - far outperforming existing silicon anode approaches.

A randomized controlled trial found that brief, evidence-based messages challenging beliefs about risk and social norms significantly reduced people's intention to panic buy - suggesting the behavior is preventable with the right communication strategy.

A severe U.S. drought in the late 1980s triggered a 42% drop in Gulf of Mexico fish biomass by cutting nutrient flow from the Mississippi River. Under high-emission scenarios, researchers project fisheries could decline over 70% by century's end.

A nationwide Danish study found that GLP-1 receptor agonists like Ozempic and Wegovy were associated with 70-84% higher preterm birth risk when used for diabetes - but showed no such link when taken for weight management, suggesting the disease drives the risk.