About The Study: This cohort study found that key sociodemographic, health care, and clinical factors are associated with receipt of semaglutide, a novel glucagon-like peptide-1 (GLP-1) receptor agonist medication, in those without diabetes. These findings suggest that insurance plan type and structure may be a crucial intervention point for improving equity in obesity treatment access.  Corresponding Author: To contact the corresponding author, Andrew C. Stokes, PhD, email acstokes@bu.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2024.55222) Editor’s ...

EMBO announces that ten life scientists have been selected to receive EMBO Installation Grants. These grants support group leaders, who are in the early stages of setting up their laboratories, to strengthen the life sciences in countries participating in the scheme. Two new installation grantees will establish laboratories in Croatia, one in Czechia, one in Estonia, two in Greece, three in Poland and one in Portugal. “EMBO Installation Grants offer flexible funding, extensive networking opportunities and practical support for life scientists pursuing ambitious research projects,” says EMBO Director Fiona Watt. ”We ...

INDIANAPOLIS -- With medical advances, more than 169,000 people in the United States are living with metastatic breast cancer. Addressing debilitating symptoms has become increasingly crucial. Fatigue remains a significant challenge, affecting up to 63 percent of patients and severely impacting daily functioning. A study demonstrates the effectiveness of telephone-delivered acceptance and commitment therapy (ACT) in reducing fatigue’s interference with functioning and improving the quality of life for survivors of metastatic breast cancer. ACT is a behavioral intervention that has shown promise in pilot studies in advanced cancer. ...

Miami (January 21, 2025) – Chronic lower respiratory diseases, including chronic obstructive pulmonary disease (COPD), are the sixth leading cause of death in the United States, according to the U.S. Centers for Disease Control and Prevention (CDC). The CDC’s National Center for Health Statistics released its “Deaths: Leading Causes for 2022” final report, ranking the 10 leading causes of death. COPD comprises several conditions, including chronic bronchitis and emphysema, and can be caused by genetics and irritants like smoke or pollution. Symptoms ...

Alcohol sales spike after a public mass shooting, according to a study. The increase in alcohol consumption could further increase firearm-related violence in affected communities. Nicholas R. Buttrick and colleagues analyzed data from 35,000 alcohol retailers, covering more than half of all American grocery and drug-store purchases from 2006–2019, and found that a public mass shooting in a community predicts a 3.5%–5.5% increase in weekly alcohol sales for at least two years. The effect is found for public shootings; mass shootings in private homes did not affect alcohol sales. The authors attribute ...

Researchers have identified peptides that can help remove microplastics from the environment by combining biophysical modeling, molecular dynamics, quantum computing, and reinforcement learning. The ultimate goal of the work is peptide-based technologies that can find, capture, and destroy microscopically tiny plastic particles.  Microplastics, plastic particles smaller than 5 mm, are ubiquitous pollutants, found everywhere from human breastmilk to Antarctic snow. Fengqi You and colleagues used a range of tools to identify peptides ...

A 2022 survey of Palestinians and Israelis identifies a set of peace deals that would be preferable to the status quo for majorities on both sides of the conflict.   Between March and May of 2022, Elisa Cavatorta and colleagues asked nationally representative samples of 1,197 Palestinians and 679 Israelis to rank hypothetical peace agreements. Each agreement consisted of eight components, varied in a controlled manner. This methodology enabled the calculation of the strength of preference for each component and the overall acceptability of 256 potential ...

Plastics are undeniably useful materials that have found their way into virtually all human activities. However, with yearly global plastic production exceeding 400 million tons, the environmental threat posed by increased plastic consumption and disposal, contributing to its pollution, is also bigger than ever. Considering that only one-tenth of all plastic waste is recycled, new technologies that can help tackle this growing problem are urgently required. Catalytic recycling techniques, such as hydrogenolysis and hydrocracking, are emerging chemical processes that can break down plastic waste into simpler components ...

Antibiotics, antivirals, vaccinations and anti-inflammatory medication are associated with reduced risk of dementia, according to new research that looked at health data from over 130 million individuals. The study, led by researchers from the universities of Cambridge and Exeter, identified several drugs already licensed and in use that have the potential to be repurposed to treat dementia. Dementia is a leading cause of death in the UK and can lead to profound distress in the individual and among those caring for them. It has been estimated to have a worldwide economic cost in excess of US$1 trillion dollars. Despite intensive ...

EUGENE, Ore. — Jan. 21, 2025 — Increased exposure to glyphosate, one of the most widely used herbicides in the United States and much of the world, harms infant health in U.S. agricultural counties, according to a new study by two University of Oregon economists. In a paper published Jan. 14 in the Proceedings of the National Academy of Sciences, Emmett Reynier and Edward Rubin showed that a dramatic increase in the use of glyphosate in U.S. counties most suitable for genetically engineered crops lowered ...

Are dogs really the key to better health and a happier life? In this new study, dog owners were invited to describe the biggest benefits and challenges of dog ownership. The commitments and responsibilities of having a dog were found to be both a joy and a burden, highlighting the importance of making a conscious adoption choice. The pet dog population has been growing worldwide. Often benefiting from good press in mainstream media, dog ownership is generally assumed to improve human lives, providing companionship and boosting well-being. While bringing a dog into the family does come with ...

After millennia as a carbon deep-freezer for the planet, regional hotspots and increasingly frequent wildfires in the northern latitudes have nearly canceled out that critical storage capacity in the permafrost region, according to a new study published in Nature Climate Change.  An international team led by Woodwell Climate Research Center found that a third (34 percent) of the Arctic-boreal zone (ABZ)—the treeless tundra, boreal forests, and wetlands that make up Earth’s northern latitudes—is now a source of carbon to the atmosphere. That balance sheet is made up of carbon dioxide (CO₂) uptake from plant photosynthesis and CO₂ ...

A study recently published by researchers from the Sant Pau Research Institute (IR Sant Pau) and the Stroke Unit of Sant Pau Hospital in the Journal of Lipid Research provides new evidence on the essential role of the qualitative properties of lipoproteins, such as LDL and HDL, in the pathophysiology of cardiovascular diseases, including ischaemic stroke. The findings underscore the importance of going beyond traditional quantitative cholesterol levels to evaluate the risk of these pathologies. Dr ...

Bladder cancer has a cure rate of over 90% when detected early, but it has a high recurrence rate of 70%, necessitating continuous monitoring. Late detection often requires major surgeries such as bladder removal followed by artificial bladder implantation or the use of a urine pouch, significantly lowering the patient’s quality of life. However, existing urine test kits have low sensitivity, and cystoscopy, which involves inserting a catheter into the urethra for internal bladder examination, is both painful and burdensome. This highlights the urgent need for a simple yet accurate diagnostic technology for patients. The research team led by Dr. Youngdo Jeong of the Center for Advanced ...

Researchers at the Autism Research Centre at Cambridge University found that these individuals also report experiencing lower quality healthcare than both autistic and non-autistic people whose gender identity matches their sex assigned at birth (cisgender). The findings have important implications for the healthcare and support of autistic transgender/gender diverse (TGD) individuals. This is the first large-scale study on the experiences of autistic TGD people and the results are published today in Molecular Autism.   Previous research suggests that both autistic people and TGD people separately have poorer healthcare experiences ...

Embargoed for release until 5:00 p.m. ET on Monday 20 January 2025    @Annalsofim          Below please find summaries of new articles that will be published in the next issue of Annals of Internal Medicine. The summaries are not intended to substitute for the full articles as a source of information. This information is under strict embargo and by taking it into possession, media representatives are committing to the terms of the embargo not only on their own behalf, but also on behalf of the organization they represent.     ...

Dr. Park Jun-woo's team at KERI's Next Generation Battery Research Center has overcome a major obstacle to the commercialization of next-generation lithium–sulfur batteries and successfully developed large-area, high-capacity prototypes.   The lithium–sulfur battery, composed of sulfur as the cathode (+) and lithium metal as the anode (-), has a theoretical energy density more than eight times that of lithium-ion batteries, demonstrating significant potential. Additionally, it uses abundant sulfur (S) instead of expensive rare earth elements, making it cost-effective and environmentally ...

A new study reported in the Cell Press journal Current Biology on January 20 is the first to describe a phenomenon researchers refer to as “contagious urinations.” The study in 20 captive chimpanzees living at the Kumamoto Sanctuary in Japan shows that, when one chimp pees, others are more likely to follow.  “In humans, urinating together can be seen as a social phenomenon,” says Ena Onishi of Kyoto University.   “An Italian proverb states, ‘Whoever doesn’t pee in company is either a thief or a spy’ (Chi non piscia in compagnia o è ...

Scientists at Harvard Medical School and Boston University Chobanian & Avedisian School of Medicine have mapped a critical component of the Nipah virus, a highly lethal bat-borne pathogen that has caused outbreaks in humans almost every year since it was identified in 1999. The advance, described Jan. 20 in Cell, brings scientists a step closer to developing much-needed medicines. Currently, there are no vaccines to prevent or mitigate infection with the Nipah virus and no effective treatments for the disease ...

Demand for weight-loss medications sold under brand names such as Ozempic and Wegovy continues to surge, with a recent study reporting one in eight Americans has taken or is currently using the drugs to treat diabetes, heart disease or obesity. Formally, these drugs are known as glucagon-like peptide-1 receptor agonists (GLP-1RA) and include Mounjaro and Zepbound. Informally, media, patients and even some physicians have dubbed GLP-1 medications as “miracle drugs” because of the profound weight loss among users. While these health benefits are well established, information is sparse on the drugs’ effects across ...

Over half of our genomes consists of thousands of remnants of ancient viral DNA, known as transposable elements, which are widespread across the tree of life. Once dismissed as the "dark side" of the genome, researchers at Helmholtz Munich and Ludwig-Maximilians-Universität (LMU) have now revealed their crucial role in early embryo development. Unanswered Questions About the Role of Ancient Viral DNA Transposable elements, remnants of ancient viral DNA, are reactivated during the first hours and days following fertilization. ...

Researchers at Karolinska Institutet and the Astrid Lindgren Children’s Hospital in Sweden have determined how children’s immune systems react to different kinds of cancer depending on their age. The study, which is published in the journal Cell, reveals significant differences between the immune response of children and adults, and has the potential to lead to new tailored treatments for children with cancer. “The activation of the immune system is crucial to our ability to fight cancer, but differs between children and adults,” says Petter Brodin, professor of paediatric immunology at the ...

Background and objectives Waist circumference (WC) is closely associated with metabolic diseases, including diabetes mellitus (DM), metabolic syndrome, and mortality. However, the correlation between WC and mortality varies across populations and has rarely been examined specifically in patients with DM. In this study, we explored the relationships between WC and both all-cause and cardiovascular mortalities among individuals with DM. Methods Participants from the National Health and Nutrition Examination Survey 2003–2018 included 3,151 women and 3,473 men with DM who had baseline WC measurements. Survival data were collected from enrollment until December 31, 2019. ...

Archaeologists have uncovered a rare Tetrarchic boundary stone at the site of Abel Beth Maacah in northern Israel. Originally marking land borders under Roman Emperor Diocletian’s tax reforms, the stone provides insight into ancient land ownership, local settlement patterns, and imperial administrative practices. The discovery also introduces two previously unknown place names, expanding our understanding of the region’s historical geography and socio-economic landscape. Archaeologists Prof. Naama Yahalom-Mack and Dr. Nava Panitz-Cohen from the Institute of Archaeology at the Hebrew University, and Prof. Robert Mullins from Azusa Pacific University have uncovered a significant ...

A global survey spanning 68 countries reveals that public trust in scientists is still high. Led by the University of Zurich and ETH Zurich, a team of 241 researchers conducted the largest post-pandemic study of trust in science, societal expectations and public views on research priorities. Trust in scientists is at a moderately high level worldwide, according to a new study. This is the conclusion of an international team of 241 researchers led by Viktoria Cologna of ETH Zurich and Niels G. Mede of the University of Zurich (UZH). “Our results show that most people in most countries have a relatively ...