PROVIDENCE, R.I. [Brown University] — A federally funded clinical trial to evaluate an intervention to prevent suicides among people recently released from jail reduced suicide attempts by 55%. That’s according to a new study in JAMA Network Open led by researchers from Brown University and Michigan State University. In the United States, one in five adults who attempts suicide has spent at least one night in jail in the year prior. With more than 10 million admissions per year and many stays of just a few days, jails touch a significant number of people at high risk for suicide who are not well connected with other support services. This ...

About The Study: U.S. individuals ages 1 to 19 are now more likely to die by firearm injury than any other cause. While this national shift occurred in 2019, Alaska had already flipped as early as 2004. Over the past 2 decades, more states flipped to firearm mortality as the predominant cause of death in this age group, including nearly half of the states in the most recent era reviewed. Corresponding Author: To contact the corresponding author, Michael L. Nance, MD, email nance@chop.edu. To ...

About The Study: In this cross-sectional study of homicides among women, state-level firearm ownership was significantly associated with all-cause and firearm-specific homicide among pregnant women, independent of state-level factors. These results suggest that homicide prevention interventions should focus on women, especially during the increased risk period of pregnancy.  Corresponding Author: To contact the corresponding author, Ayesha Dholakia, MD, email ayesha.dholakia@childrens.harvard.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2025.42447) Editor’s ...

Investigators at Mass General Brigham have found that cases of child abuse and neglect in the United States have declined overall over the last decade, but disparities have persisted and in some cases widened. Poverty, which likely underlies much of the observed gaps, was highlighted as a critically important target for intervention. The research is published in JAMA Pediatrics.   “Poverty is a relentless source of stress that permeates families, creating an environment where the struggles for survival may overshadow the nurturing ...

Osaka, Japan - A research team from The University of Osaka, in collaboration with the Massachusetts Institute of Technology, has uncovered a new molecular mechanism underlying chromosome alignment during cell division. The study demonstrates that two motor proteins, KIF18A and CENP-E, act cooperatively to ensure proper chromosome congression. Remarkably, simultaneous inhibition of these proteins selectively kills cancer cells, suggesting a promising therapeutic avenue. Accurate chromosome segregation is essential for healthy cell division; its failure leads to chromosomal instability—a hallmark of cancer. While the kinetochore, a protein complex on chromosomes, coordinates this ...

The American College of Medical Genetics and Genomics (ACMG) has published a new clinical practice resource, “Management of Individuals with Heterozygous Germline Pathogenic Variants in RAD51C, RAD51D, and BRIP1: A clinical practice resource of the American College of Medical Genetics and Genomics (ACMG),” in its official journal, Genetics in Medicine. The publication provides evidence-based guidance for clinicians managing individuals with heterozygous germline pathogenic variants (GPVs) in RAD51C, ...

One of the most devastating moments for family members of a patient with Alzheimer’s is when their loved one forgets who they are. New University of Virginia School of Medicine research may explain why that happens and could lead to a way to prevent it. UVA’s Harald Sontheimer, PhD, and graduate student Lata Chaunsali and their colleagues found that the failure to recognize family, friends and caregivers is caused by the breakdown of protective “nets” that surround neurons in the brain. ...

“This environmentally friendly technique represents a novel approach to nanoparticle fabrication, emphasizing sustainability in nanotechnology.” BUFFALO, NY – November 10, 2025 – A new research paper was published in Oncotarget (Volume 16) on November 6, 2025, titled “Anti-DNA virus agent cidofovir – loaded green synthesized cerium oxide nanoparticles (Nanoceria): Nucleic acids (DNA and RNA) binding affinity and cytotoxicity effects.” In ...

What factors help English learners (ELs) succeed in schools? In a study of top performing New York City high schools serving immigrant ELs, researchers linked three conditions—teacher autonomy, collaboration, and collective responsibility—to higher credit attainment. “Most research on ELs focuses on classroom instruction or broader language policies, but our study describes the professional conditions that positively impact outcomes for immigrant ELs,” says Adriana Villavicencio, lead author and assistant professor of educational leadership and policy studies at NYU Steinhardt. “We took this approach to address a dearth ...

In 2023, astronomers detected a huge collision. Two unprecedentedly massive black holes had crashed an estimated 7 billion light-years away. The enormous masses and extreme spins of the black holes puzzled astronomers. Black holes like these were not supposed to exist. Now, astronomers with the Flatiron Institute’s Center for Computational Astrophysics (CCA) and their colleagues have figured out just how these black holes may have formed and collided. The astronomers’ comprehensive simulations — which follow the system from the lives of the parent stars through to their ultimate death — uncovered ...

Blue Zones and the American College of Lifestyle Medicine (ACLM) today launched the “Blue Zones Certification Course for Physicians and Health Professionals.” The new certification recognizes clinicians with the knowledge and tools to promote longevity, well-being, and health equity—both in the exam room and in their communities. The certification integrates Blue Zones' evidence-based roadmap to living better and longer, rooted in their identification of and research from the world's longest-lived and happiest cultures—the blue zones regions—with ACLM's ...

SAN ANTONIO — November 10, 2025 — Southwest Research Institute (SwRI) has demonstrated a new application for its cell-expansion bioreactor to advance tissue engineering and cell-based therapies for treatment of injuries and diseases. SwRI scientists used the bioreactor to replicate induced Pluripotent Stem Cells (iPSCs) derived from adult skin, blood, and other somatic cells. Their pluripotent state allows iPSCs to differentiate into any other cell type in the body, much like embryonic stem cells but without the same ethical ambiguity. Large quantities ...

Trial Showing Ivermectin Safety in Small Children Could Spur Progress Against Several Neglected Tropical Diseases TORONTO (November 10, 2025)—Millions of very young children currently excluded from treatment with the drug ivermectin could be safely included in ongoing campaigns against challenging and often neglected tropical diseases such as intestinal worms, scabies and river blindness, according to results from a clinical trial presented today at the Annual Meeting of the American Society ...

PLYMOUTH MEETING, PA [November 10, 2025] — New research in the November 2025 issue of JNCCN—Journal of the National Comprehensive Cancer Network explores the perceptions regarding the effectiveness of team-based and technology-based approaches for supportive care for people with cancer. The ongoing supportive care study includes discussions on patient goals, values, and preferences, in addition to symptom management. According to the results from this mixed-methods study, 87.5% of team-based clinic participants perceived that method is more ...

New York, NY (November 10 2025) — In a high honor, Jean-Frédéric Colombel, MD, a leading inflammatory bowel disease (IBD) expert at the Icahn School of Medicine at Mount Sinai, will deliver the 31st Anatomy Lesson on Thursday, November 20, at the Concertgebouw in Amsterdam. His lecture, “Tackling the Growing Problem of Immune Diseases—Crohn’s Disease as an Example,” will explore Mount Sinai’s pioneering work in the early detection, prevention, and treatment of IBD. The Anatomy Lesson, an annual public lecture organized by Amsterdam UMC, invites leading international physicians and researchers to reflect on medicine’s ...

When researchers look for potential cancer therapy targets, they typically go after protein-coding genes that participate in disease progression. Disrupt them and negate whatever role they play in cancer’s development or spread. Researchers at Cold Spring Harbor Laboratory (CSHL) have also been working on another kind of target. They’re studying a long non-coding RNA called MALAT1. So far, it’s been linked to more than 20 different types of tumors. In a new and unique study published in Molecular Therapy: Oncology, CSHL researchers track MALAT1 levels ...

ORLANDO (NOV. 9, 2025) – Allergist Cherie Zachary, MD, of Bloomington, MN was installed as president of the American College of Allergy, Asthma and Immunology (ACAAI) at the ACAAI Annual Scientific Meeting on November 10 in Orlando. Allergist David Stukus, MD, of Columbus, OH, was elected ACAAI president-elect. Other newly-elected ACAAI officers are Maureen Petersen, MD, of Clayton, NC, as vice president and Melinda Rathkopf, MD, MBA, of Atlanta, GA, as treasurer. Regents elected for three-year terms include Christopher C. Chang, MD, PhD, MBA, Hollywood, Florida, Mitchell H. Grayson, MD, Columbus, OH, and Jay A. Lieberman, ...

More than 99% of the world’s 7.7 billion people have one or more of their environmental rights threatened, according to new research. In the most comprehensive analysis of inequality in environmental conditions to date, CU Boulder researchers revealed that nearly half of the global population lives in regions facing three or more environmental problems. Those include polluted air, unsafe water, extreme heat, food insecurity and biodiversity loss. The analysis was published September 25 in Environmental Research Communications. It provides strong ...

A hormone produced in the thyroid gland can play a key role in the development of prostate cancer. This is shown in a new study by an international research group led by Umeå University, Sweden, and the Medical University of Vienna, Austria. By blocking a receptor for the hormone, the growth of tumour cells in the prostate was inhibited. In the long term, the discovery may open up a new way of attacking certain types of aggressive prostate cancer. "The results indicate that the receptor in question is a driving force in the growth of cancer. Substances that block it could thus be a target for future drugs against prostate cancer," ...

New Curtin University research has found invasive cane toads are on track to reach Western Australia’s Pilbara region within the next 10 to 20 years, threatening to cause widespread losses among native species and significant cultural and economic harm. The study, published in Scientific Reports, predicts that without containment efforts, the toxic amphibians will colonise up to 75 per cent of the Pilbara within three decades, putting 25 native species at risk of serious population declines. These include several species of native marsupial predators like northern quolls, ghost bat and kaluta, as well as frog-eating snakes, blue-tongue skinks and goannas. Of ...

As world leaders begin COP30 climate negotiations in Brazil this week, an international team co-led by a University of Sydney researcher has warned of a hidden crisis undermining global biodiversity and carbon targets: the quiet abandonment of conservation projects. The comment paper, ‘Conservation abandonment is a policy blind spot’, published in Nature Ecology & Evolution, was co-led by Dr Matthew Clark, a postdoctoral researcher in the Thriving Oceans Research Hub at the University of Sydney and an honorary research associate in the Centre for Environmental Policy at Imperial College ...

Iron deficiency is globally widespread. Women are particularly affected, with one in five in Europe suffering from iron deficiency. The consequences are anaemia, constant fatigue, chronic headaches and a weakened immune system. Researchers led by ETH professor Raffaele Mezzenga have now developed a new dietary supplement that could efficiently treat iron deficiency and anaemia. This development is being co-led by Michael B. Zimmermann, professor emeritus at ETH Zurich. The preparation consists of edible oat protein ...

Understanding the properties of different materials is an important step in material design. X-ray absorption spectroscopy (XAS) is an important technique for this, as it reveals detailed insights about a material’s composition, structure, and functional characteristics. The technique works by directing a beam of high-energy X-rays at a sample and recording how X-rays of different energy levels are absorbed. Similar to how white light splits into a rainbow after passing through a prism, XAS produces a spectrum of X-rays with different energies. This spectrum is called as spectral data, which acts like an unique fingerprint of a material, ...

Portable genetic sequencers used around the world to sequence DNA have critical, previously unreported security vulnerabilities that could reveal or alter genetic information without detection, according to a new study. Researchers from the University of Florida have, for the first time, exposed these security risks in devices from Oxford Nanopore Technologies, which produces nearly all the portable genetic sequencers in the world. Alerted by the security researchers, Oxford Nanopore Technologies has rolled out updated software to patch the vulnerabilities. But out-of-date software, or unsecured internet systems, could still leave some DNA sequencers vulnerable ...

ITHACA, N.Y. - As the everyday use of AI has exploded in recent years, so have the energy demands of the computing infrastructure that supports it. But the environmental toll of these large data centers, which suck up gigawatts of power and require vast amounts of water for cooling, has been too diffuse and difficult to quantify. Now, Cornell researchers have used advanced data analytics – and, naturally, some AI, too – to create a state-by-state look at that environmental impact. The team found that, by 2030, the current rate of AI growth would annually put 24 to 44 million metric tons of carbon dioxide into the ...