New molecule reduces ethanol intake and drinking motivation in mice, with sex-dependent differences
2025-11-11
A new compound tested at the Miguel Hernández University of Elche (UMH) in Spain shows promising effects in reducing alcohol consumption and motivation to drink in mice, with marked sex-dependent differences in efficacy. Although MCH11 is not yet available for human use, it could pave the way for personalized treatments of alcohol use disorder.
The results, published in the journal Biomedicine & Pharmacotherapy, stem from four years of work by a team from the Institute of Neurosciences (a joint UMH–CSIC centre), the Institute for Health and Biomedical ...
AI adoption in the US adds ~900,000 tons of CO₂ annually, equal to 0.02% of national emissions
2025-11-11
A new study published in Environmental Research Letters finds that continued growth in artificial intelligence (AI) use across the United States could add approximately 900,000 tonnes of CO₂ annually. This is not a small amount but equates to a relatively minor increase when viewed in the context of nationwide emissions.
While AI adoption is expected to boost productivity and economic output, researchers note that its environmental footprint can be seen as relatively modest compared to other industrial activities. The study examined potential AI integration across various sectors, estimating ...
Adenosine is the metabolic common pathway of rapid antidepressant action: The coffee paradox
2025-11-11
NEW YORK, New York, USA, 11 November 2025 -- Perhaps the most intriguing implication of recent breakthrough research lies in an unexpected connection: the most rigorous mechanistic dissection of rapid antidepressant action identifies adenosine as the critical mediator, yet adenosine receptors are the primary target of caffeine, the world's most widely consumed psychoactive substance.
A commentary published today in Brain Medicine by Drs. Julio Licinio and Ma-Li Wong explores this striking convergence. Is this merely coincidence, or ...
Vegan diet can halve your carbon footprint, study shows
2025-11-11
Only around 1.1% of the world's population is vegan, but this percentage is growing. For example, in Germany the number of vegans approximately doubled between 2016 and 2020 to 2% of the population, while a 2.4-fold increase between 2023 and 2025 to 4.7% of the population has been reported in the UK. Many people cite health benefits as their reason to go vegan: moving from a typical Western diet to a vegan one can lower the risk of premature mortality from noncommunicable diseases by an estimated 18% to 21%.
Another excellent reason is to reduce your ecological footprint. Now, a study in Frontiers in Nutrition has calculated precisely how ...
Anti-amyloid therapy does not change short-term waste clearance in Alzheimer’s
2025-11-11
A group from Osaka Metropolitan University in Japan, led by graduate student Tatsushi Oura and Dr. Hiroyuki Tatekawa, found that treatment using the drug lecanemab to remove amyloid plaques in the brain does not change the waste clearance function in the brains of Alzheimer’s disease (AD) patients in the short term.
This suggests that even after treatment, the AD patients’ nerves are already damaged, and the waste clearance function does not recover in the short term. Their findings show the complexity of the disease and the need to address multiple disease-causing pathways simultaneously in the future.
Their findings add to the complicated process of unraveling ...
Personalized interactions increase cooperation, trust and fairness
2025-11-11
A new setup for social games suggests that when people are given the freedom to tailor their actions to different people in their networks, they become significantly more cooperative, trusting and fair. The international study with Kobe University participation thus argues that many standard experimental setups of cooperation underestimate people’s prosocial potential.
Games that are models of social interactions are used in sciences spanning from sociology and anthropology to psychology and economics, giving us very concrete data on how likely it is that people behave in a certain way in certain social contexts. For example, when modeling how people cooperate in social networks, ...
How are metabolism and cell growth connected? — A mystery over 180 years old
2025-11-11
A research team including a scientist of Earth-Life Science Institute (ELSI) at Institute of Science Tokyo, Japan, has identified a novel principle in biology that mathematically explains why the growth of organisms slows as nutrients become more abundant—a phenomenon known as “the law of diminishing returns.”
Understanding how living organisms grow under various nutritional environments has long been a central question in biology. Across microbes, plants, and animals, growth is shaped by the availability of nutrients, energy, and cellular machinery. While extensive ...
Novel transmission technique enables world record 430 Tb/s in a commercially available, international-standard-compliant optical fiber
2025-11-11
Highlights
- A new optical transmission record of 430 Tb/s, surpassing the previous record of 402 Tb/s.
- The breakthrough leverages international-standard-compliant, cutoff-shifted optical fibers with a novel approach that triples the capacity of certain spectral regions using spatial-division multiplexing.
- This innovation promises to enhance metropolitan networks and inter-datacenter links by offering high throughput with reduced complexity, while utilizing existing optical fiber infrastructure.
Abstract
The National Institute of Information and Communications Technology (NICT, President: TOKUDA Hideyuki, Ph.D.), together with 11 international ...
Can risk prediction tools identify patients at risk of overdose or death after “before medically advised” hospital discharge?
2025-11-11
Risk prediction tools might help identify patients at the highest risk of overdose and death after a “before medically advised” (BMA) hospital discharge according to new research in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.250492.
Patients who leave hospital against the advice of a physician are about twice as likely to die and about 10 times more likely to experience an illicit drug overdose in the first 30 days after leaving hospital. Such BMA discharges are initiated ...
Dreaming of fewer running injuries? Start with better sleep
2025-11-11
If you are among the 620 million people who lace up their running shoes on a regular basis, chances are that you’re an early riser.
Hopefully, you will have got at least eight hours of good sleep the night before, otherwise your risk of injury skyrockets.
That’s the finding from a new study led by Professor Jan de Jonge, a work and sports psychologist at Eindhoven University of Technology in the Netherlands, and an Adjunct Professor at the University of South Australia.
In a survey of 425 recreational runners, Prof de Jonge and his team found that those reporting shorter sleep duration, lower sleep ...
USC study links ultra-processed food intake to prediabetes in young adults
2025-11-11
More than half of calories consumed in the United States come from ultra-processed foods (UPFs), items like fast food and packaged snacks that are often high in sodium, sugar and unhealthy fats. In adults, research has clearly linked these foods to type 2 diabetes and other conditions, but few studies have explored their effects among youth.
Now, researchers from the Keck School of Medicine of USC have completed one of the first studies to examine the link between UPF consumption and how the body processes glucose, which is ...
How life first got moving: nature’s motor from billions of years ago
2025-11-11
Research led by the University of Auckland has cast light on the evolutionary origins of one of nature’s first motors, which developed 3.5 billion to 4 billion years ago to propel bacteria.
Scientists have created the most comprehensive picture yet of the evolution of bacterial stators, proteins with roles similar to pistons in a car engine, says Dr Caroline Puente-Lelievre, of the School of Biological Sciences.
Stator proteins sit in the bacterial cell wall, transforming charged particles (ions) into torque, creating propulsion for bacteria to swim.
Stators likely evolved from ion transporter ...
The 2nd International Conference on Civil Engineering and Smart Construction (ICCESC 2025)
2025-11-11
The evolution of civil and hydraulic engineering spans across historical eras, deeply intertwined with societal, economic, and scientific advancement. Particularly, it mirrors the progress in science and technology. Emerging as the harmonious amalgamation of contemporary information technology and construction, intelligent construction emerges as the prime catalyst propelling the transformation and enhancement of the construction sector, steering it towards modernization.
Centered around civil engineering, water management, and intelligent construction, this conference strives to bridge the latest scholarly accomplishments ...
Hidden catalysis: Abrasion transforms common chemistry equipment into reagents
2025-11-11
The chemical industry is one of the largest on the planet, essential for supplying us with pharmaceuticals, agrochemicals, materials and more. Great care is taken to optimize reagents and conditions for each reaction, striving for efficiency and, increasingly, sustainability. A growing field of synthesis is mechanochemistry, in which reagents are mixed using mechanical force, making for greener reactions with less solvent usage and enabling access to a wide array of essential chemicals.
In a typical mechanochemistry setup, the reagents are placed in a jar ...
ASH 2025 tip sheet: Sylvester researchers contribute to more than 35 oral presentations at ASH Annual Meeting
2025-11-11
Mosunetuzumab and polatuzumab combined with axicabtagene ciloleucel induce high complete response rates at day+90 in Relapsed/Refractory large B-cell lymphoma
Dr. Jay Spiegel is the presenting author and all other authors are with Sylvester or the University of Miami.
A phase 2 trial of abbreviated fixed-duration (Default 4 Cycles) linvoseltamab immuno-consolidation to deepen responses post newly diagnosed multiple myeloma combination therapy for minimal residual disease positivity (the IMMUNOPLANT Study) ...
Feeling fit, but not fine: ECU study finds gap between athletes’ health perceptions and body satisfaction
2025-11-11
New research from Edith Cowan University (ECU) has revealed a striking disconnect between how recreational athletes perceive their health and fitness, and how they feel about their bodies.
The research found that while 69 per cent of recreational athletes that participated in a survey considered themselves healthy and 62 per cent believed they were fit, only 26 per cent reported being satisfied with their body weight and shape.
The findings confirm a concerning trend that athletes, particularly those engaged in regular or structured physical activity, are statistically more likely to experience disordered eating and exercise behaviours ...
The flexible brain: How circuit excitability and plasticity shift across the day
2025-11-11
Our brains do not react in a fixed, mechanical way like electronic circuits. Even if we see the same scene every day on our commute to work, what we feel - and whether it leaves a lasting impression - depends on our internal state at that moment. For example, your commute may be a blur if you're too tired to pay attention to your surroundings.
The 24-hour cycle that humans naturally follow is one of the factors that shapes the brain's internal environment. These internal physiological cycles arise from ...
New self-heating catalyst cleans antibiotic pollutants from water and soil
2025-11-11
Scientists have developed a fast, energy-efficient method to create an iron-carbon (Fe/C) catalyst that can remove antibiotic pollutants from both water and soil by using oxygen from the air. The study, published in Sustainable Carbon Materials, introduces a self-heating synthesis approach that could pave the way for greener environmental cleanup technologies.
Antibiotic residues such as sulfamethoxazole, commonly found in wastewater and agricultural runoff, are a growing environmental concern. These contaminants persist in the environment and ...
Could tiny airborne plastics help viruses spread? Scientists warn of a hidden infection risk
2025-11-11
As plastic pollution worsens worldwide, scientists are uncovering a new and unsettling possibility. Tiny airborne fragments of plastic, known as micro- and nanoplastics, may do more than pollute the air we breathe. They could also help viruses linger and travel farther, potentially influencing how respiratory diseases spread.
A commentary published in New Contaminants by Mengjie Wu and Huan Zhong of Nanjing University calls attention to the emerging concern that airborne plastics might act as invisible vehicles for viruses. While plastics ...
Breakthrough in water-based light generation: 1,000-fold enhancement of white-light output using non-harmonic two-color femtosecond lasers
2025-11-11
Scientists at Japan's Institute for Molecular Science have achieved a 1,000-fold enhancement in white-light generation inside water by using non-harmonic two-color femtosecond laser excitation. This previously unexplored approach in liquids unlocks new nonlinear optical pathways, enabling a dramatic boost in supercontinuum generation. The breakthrough lays a foundation for next-generation bioimaging, aqueous-phase spectroscopy, and attosecond science in water.
Researchers at the Institute for Molecular ...
Food stamp expansion in 2021 reduced odds of needy US kids going hungry
2025-11-11
The 15% expansion of food stamp payments under the supplemental nutrition assistance program, or SNAP for short, during the COVID-19 pandemic, reduced the odds of needy children going hungry, especially in Hispanic-American and large households, finds research to be published online in the Journal of Epidemiology & Community Health.
The findings are particularly relevant, given the projected 9-10% benefit reductions ($15/household/month) for typical families by 2034 under the terms of the 2025 Reconciliation Bill enacted in July ...
Cash transfers boost health in low- and middle-income countries
2025-11-11
Philadelphia, PA — Large-scale, government-led cash transfer programs drove significant improvements in health outcomes across low- and middle-income countries (LMICs), according to a major new study in The Lancet from researchers at the University of Pennsylvania Perelman School of Medicine. More women received health care early in their pregnancies, more babies were born in health facilities, and more births were attended by trained health workers when governments gave money through cash transfer programs.
Giving cash leads to massive health improvements
Researchers ...
LDL cholesterol improved among veterans in program with health coaches, other resources
2025-11-10
Research Highlights:
After 24 months, 34% of veterans who have heart and blood vessel disease and high cholesterol in a quality improvement program that included health care coaches and other resources had improved cholesterol levels to below 70 mg/dL.
The quality-improvement program increased the number of military veterans with better LDL (“bad” cholesterol) levels of less than 70mg/dL, and more than a third of those ages 75 and older achieved their lower cholesterol goal.
Note: The study featured in this news release is a research abstract. Abstracts ...
New study finds novel link between shared brain-gene patterns and autism symptom severity in children with autism and ADHD
2025-11-10
NEW YORK, NY (November 2025) A new study published in Molecular Psychiatry reveals that the biological underpinnings of autism and ADHD may transcend traditional diagnostic boundaries. While there is increasing appreciation that ADHD and autism often co-occur, the underlying shared biological features have remained largely unknown. Researchers from the Child Mind Institute and collaborating institutions discovered that autism symptom severity, rather than diagnostic classification, corresponds to distinct ...
For Black adults in food deserts, food delivery & dietary guidance reduced blood pressure
2025-11-10
Research Highlights:
A grocery support program based on the low-sodium DASH eating plan that included home-delivered groceries and dietary counseling reduced blood pressure levels in Black adults living in areas where grocery stores were inaccessible or scarce, known as food deserts.
People who had groceries delivered to their homes and followed guidance from a dietitian for three months had greater improvements in blood pressure and cholesterol levels, compared to a similar group in the same community ...
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