Despite growing recognition that elevated Lp(a) is an independent cardiovascular risk factor, a new study shows that clinicians seldom initiate lipid-lowering therapy after detecting high levels - even when results suggest increased danger.

Researchers at Jeonbuk National University developed a clustering-based machine learning framework that trains one model per group of hydrologically similar stations, enabling accurate water level forecasts even where historical records are sparse.

Simulations from six global models show that aggressive climate mitigation (1.5C target) could put 56 million more people at risk of hunger by 2050 through higher food prices. But the same policies reduce ozone pollution, boosting crop yields enough to offset about 15% of that increase - with 56% of benefits concentrated in Sub-Saharan Africa and India.

Oxford-led research identifies L 98-59 d as a potential new class of exoplanet - one sustaining a permanent magma ocean that stores massive sulfur reserves and maintains a thick, hydrogen-sulfide-rich atmosphere. Published in Nature Astronomy, the finding suggests planetary diversity may be greater than current models allow.

University of Edinburgh scientists engineered E. coli bacteria to convert PET plastic waste into L-DOPA, a frontline Parkinson's disease medication. Published in Nature Sustainability, the process breaks PET into terephthalic acid, which bacteria then transform through a series of biological reactions into the drug.

The Alliance for Clinical Trials in Oncology is launching a phase III trial testing whether adding vorasidenib, a brain-penetrant IDH inhibitor, to standard temozolomide chemotherapy after radiation improves progression-free survival in newly diagnosed grade 3 IDH-mutant astrocytoma. The study aims to enroll 400 patients.

The NIH-funded Baby CHAMP trial compared three intensive therapies for infants with unilateral cerebral palsy: two forms of constraint-induced movement therapy and bimanual training. All three produced significant, lasting improvements in hand function, with gains continuing six months after treatment ended. No approach proved superior.

A University of Michigan national poll of 1,780 parents found that over half witnessed unsafe driving by their teen or young adult, yet 96% rated their child as an average or better driver. Only one in four took corrective action, despite one in three worrying their child could cause a crash.

Researchers mapped cellular mechanisms behind fibrosis in Crohn's Disease, finding that endothelial cells cluster around immune aggregates in the submucosa and signal fibroblasts to overproduce collagen. Published in The Journal of Pathology, the work identifies potential therapeutic targets for a complication that currently requires surgery.

Researchers at Osaka Metropolitan University used lipocalin-type prostaglandin D synthase (L-PGDS) as a novel carrier for Paclitaxel, improving the drug's solubility 3,600-fold and achieving sustained antitumor effects in a mouse breast cancer model even after treatment stopped.

Researchers at Doshisha University developed DUPGT-CDR, a deep learning framework that separately processes positive and negative user ratings to improve recommendations for new-platform users. Tested on Amazon review data, it reduced prediction errors by up to 20.9% compared to existing cross-domain methods.

A study of 1.1 million Ontario births found that extending monitoring for severe maternal morbidity from labor and delivery to the full period from conception through six weeks postpartum captured over 40% more cases. Sixteen percent occurred prenatally and 29% postpartum - periods largely invisible to current Canadian surveillance.

A study of nearly 500,000 births in Ontario found that Asian parents experience 1.5 times the obstetric trauma rate of White parents, while Black economic immigrant and refugee parents face 20-30% higher risk. Duration of residence in Canada was associated with declining risk, suggesting better care access over time.

The American College of Sports Medicine published its first resistance training update since 2009, based on 137 systematic reviews and over 30,000 participants. The central message: any resistance training improves strength, muscle size, and function. Elastic bands, bodyweight, or barbells - consistency beats complexity.

The largest global study of emergency patients presenting with visible blood in urine found that 10% die within 90 days and 25% have underlying cancer. Patients who received a CT scan or cystoscopy within 48 hours were diagnosed faster and had better outcomes. The WASHOUT study spanned 8,500 patients across 380 hospitals.

New research comparing prostate cancer screening with Germany's established breast cancer program finds similar rates of significant cancer detection and biopsy accuracy, with prostate biopsies actually more likely to find significant cancer (50-68% vs 10%). The findings, presented at EAU26, challenge the rationale for rejecting organized prostate screening.

Insilica's ToxIndex platform uses AI agents to produce comprehensive toxicological risk assessments in hours instead of months. Endorsed by Johns Hopkins CAAT director Thomas Hartung, the platform integrates 600+ open-source models, in vitro evidence from 60 billion data triples, and regulatory databases to deliver fully traceable safety evaluations.

The RESIL-Card consortium has launched a free online tool that helps hospital cardiovascular teams assess how well their care pathways would hold up during a crisis. Developed through EU4Health funding with input from clinicians, patients, and policymakers across Europe, it guides teams through a four-step resilience evaluation.

Tokyo Metropolitan University researchers have detected laser-assisted electron scattering using circularly polarized light for the first time - a technical milestone that could reveal how atomic-scale chirality affects electron behavior. The signal matched theoretical predictions from Kroll-Watson theory.

A 12-week trial of the Melonga App found that men using the app doubled their time to ejaculation (from 61 to 125 seconds), with 22% no longer meeting criteria for premature ejaculation. The CLIMACS study, presented at the EAU Congress 2026, is the first to test an app-based treatment for the condition.

A juvenile female fisher traveled 118 kilometers from Durham to Lincoln, New Hampshire - the longest dispersal ever recorded for the species - through deep winter snow. The finding, published in Northeastern Naturalist, underscores the need for connected forest habitats as fisher populations decline.

Indiana has signed House Bill 1266, requiring data science integration across all K-12 subjects and creating a dedicated high school data science track covering AI engineering and computer science. The law follows a statewide summit and aims to replicate Indiana's jump to sixth nationally in reading.

A single injection of self-amplifying RNA into skeletal muscle produced a cardiac repair hormone called ANP that reduced scarring and improved heart function across multiple animal models, including aged mice and diabetic animals, for at least four weeks.

Research across China and North America found that abusive supervision triggers organizational dehumanization - making employees feel like tools rather than people - which drives burnout through inauthenticity and kills teamwork through perceived powerlessness.

Rice University developed a hydrogel from chitosan - a crustacean shell polymer - that encapsulates electroactive bacteria near an electrode, solving the mediator loss problem in liquid environments and enabling a living sensor that detected sakacin P in milk.