A new study published in Science Advances by researchers from the Guangzhou Institute of Geochemistry of the Chinese Academy of Sciences (GIG-CAS), along with international collaborators, reveals that deeply subducted carbonates can cause significant variations in the redox states of Earth's mantle. This process influences the formation of sublithospheric diamonds and plays a role in the long-term evolution of cratons—ancient stable parts of the continental lithosphere. The research team conducted high-pressure experiments simulating depths between ...

LONDON, ON – Mouth taping, a growing trend on social media channels like TikTok, carries serious health risks, especially for those with sleep-disordered breathing and obstructive sleep apnea, according to a paper published today in PLOS One.  The study from Lawson Research Institute (Lawson) of St. Joseph’s Health Care London, London Health Sciences Centre Research Institute (LHSCRI) and Western University’s Schulich School of Medicine & Dentistry also found no strong evidence of health benefits.  The trend involves ...

Tampa, FL, USA, May 21, 2025: The Global Virus Network (GVN) strongly supports the World Health Organization’s (WHO) newly adopted Pandemic Preparedness Accord. This agreement represents a vital and timely step toward establishing a more coordinated, transparent, and equitable global framework for pandemic prevention, preparedness, and response. GVN, an international coalition of leading virologists and research centers in over 40 countries, has consistently advocated for the critical components reflected in the Accord. Our recent statement ...

BOSTON – A new risk assessment score developed by researchers at Dana-Farber Cancer Institute and the Broad Institute of MIT and Harvard reveals how multiple myeloma, a form of blood cancer, begins and progresses from precancerous to malignant states by tracing DNA mutations. The score, called an MM-like score, assesses the severity of disease and risk of progression to active cancer, with higher scores indicating faster progression. In the future, the MM-like score could be used in clinical practice to inform decisions about early intervention.  “In patients with a precursor condition for multiple myeloma, the multiple myeloma-like score helps to predict ...

Laser frequency combs are light sources that produce evenly spaced, sharp lines across the spectrum, resembling the teeth of a comb. They serve as precise rulers for measuring time and frequency, and have become essential tools in applications such as lidar, high-speed optical communications, and space navigation. Traditional frequency combs rely on large, lab-based lasers. However, recent advancements have led to the development of chip-scale soliton microcombs, which generate ultrashort pulses of light within microresonators. One of the key challenges for soliton microcombs is timing jitter, which refers to tiny fluctuations ...

When a neuron in our body gets damaged, segments of RNA produce proteins that can help repair the injury. But in neurological disorders such as ALS and spinal muscular atrophy, or following spinal cord injuries, the mechanisms for moving life-essential RNA to injured sites within the cell fail. As a result, RNA molecules can’t get to where they are needed and damage becomes permanent. Researchers at Stanford have developed a technology for transporting RNA to specific locations within a neuron, ...

WINSTON-SALEM, N.C. – May 21, 2025 – A new study from researchers at Wake Forest University School of Medicine shows an improvement in screening rates for anxiety and depression among epilepsy patients with the implementation of an electronic health record (EHR)-based strategy.  The findings appear online in the Journal of Clinical and Translational Science.  “Anxiety and depression are common in epilepsy, yet they are often under-recognized and undertreated,” said Heidi Munger Clary, M.D., ...

An international team of researchers has found a genetic link to long-term symptoms after COVID-19. The identified gene variant is located close to the FOXP4 gene, which is known to affect lung function. The study, published in Nature Genetics, was led by researchers at Karolinska Institutet in Sweden and the Institute for Molecular Medicine Finland. Biological causes behind persistent symptoms after COVID-19 infection, known as long COVID or post-COVID, remain unclear. Common symptoms include fatigue, cognitive difficulties, and breathing problems, which can reduce quality of life. In an international collaboration – the Long COVID ...

NEW ORLEANS, May 21, 2025 – Have you ever walked through the ruins of an ancient city and wondered what life sounded like back then? So has Sezin Nas, a researcher of interior architecture and acoustics at Istanbul Galata University. The ancient, underground city of Derinkuyu caught Nas’s eye early on. Located in modern-day Turkey, Derinkuyu was built underground to defend against invasion, protect its citizens from harsh weather, and safely store agricultural products. At its peak, it could hold up to 20,000 people. The city spanned seven levels underground, with four main ventilation channels and over 50,000 other ...

EMBARGOED UNTIL: 8:15 a.m., Wednesday, May 21, 2025   Session:  D13—Current Research in Critical and Acute Care Neighborhood Health Measured by the Healthy Places Index (HPI), but Not by the Area Deprivation Index (ADI), Is Associated with Mortality for Critically Ill Sepsis Patients in the San Francisco Bay Area Date and Time: Wednesday, May 21, 2025, 8:15 a.m. Location: Room 25, Hall E (North Building, Exhibition Level), Moscone Center   ATS 2025, San Francisco – Living in a disadvantaged neighborhood is linked to worse health outcomes, but there are significant differences in how ...

EMBARGOED UNTIL: 8:15 A.M. PT, WEDNESDAY, MAY 21, 2025   Session:  D19—In the Shallow: Exploring Sleep Related Hypoventilation Disorders Rapid Eye Movement Sleep-Suppressing Antidepressant Use Is Associated with Enhanced Survival in Amyotrophic Lateral Sclerosis 
Date and Time: Wednesday, May 21, 2025, 8:15 a.m. PT 
Location: Room 2018 (West Building, Level 2), Moscone Center   ATS 2025, San Francisco – During REM sleep, the body enters a state of paralysis. This can pose a danger for patients with weakened diaphragms due to neuromuscular diseases. Now new research ...

Just a few meters beneath the clear, blue waters of Okinawa, reef-building corals known as Scleractinia have quietly lived for centuries. Slowly, layer by layer, they have constructed intricate, rigid structures made of calcium carbonate to form the vibrant coral reefs of today. Now, researchers have developed a comprehensive system to identify the diversity of these hard corals using only a sample of surface seawater. This environmental DNA (eDNA) metabarcoding system can successfully detect 83 of the 85 genera of reef-building corals known in Japan, enabling their effective and high-precision ...

Lake Tahoe is experiencing large-scale shifts in ultraviolet radiation (UV) as climate change intensifies wet and dry extremes in the region. That is according to a study led by the University of California, Davis' Tahoe Environmental Research Center and co-leading collaborator Miami University in Ohio. For the study, published in ASLO, the journal of the Association for the Sciences of Limnology and Oceanography, scientists analyzed an 18-year record of underwater irradiance at Lake Tahoe, which is renowned ...

We’ve all felt the sting of guilt when fruit and vegetables go bad before we could eat them. Now, researchers from MIT and the Singapore-MIT Alliance for Research and Technology (SMART) have shown they can extend the shelf life of harvested plants by injecting them with melatonin using biodegradable microneedles. That’s a big deal because the problem of food waste goes way beyond our salads. More than 30 percent of the world’s food is lost after it’s harvested — enough to feed more than 1 billion people. Refrigeration is the most common way to preserve foods, but it requires energy and ...

As rates of depression and suicide in youth spike, experts are asking whether social media makes kids depressed — or do depressed kids simply spend more time on social media? A new study provides answers. Researchers at UC San Francisco found that as preteens used more social media, their depressive symptoms increased. Yet the reverse wasn’t true — a rise in depressive symptoms didn't predict a later increase in social media use. On average, kids' social media use rose from seven to 73 minutes per day over the three ...

About The Study: In this cohort study of more than 11,000 children and adolescents, reporting higher than person-level mean social media use in years 1 and 2 after baseline was associated with greater depressive symptoms in the subsequent year. The findings suggest that clinicians should provide anticipatory guidance regarding social media use for young adolescents and their parents. Corresponding Author: To contact the corresponding author, Jason M. Nagata, MD, email Jason.nagata@ucsf.edu. To access the embargoed study: Visit ...

About The Study: Analysis of newly launched children’s ready-to-eat cereals from 2010 to 2023 revealed concerning nutritional shifts: notable increases in fat, sodium, and sugar alongside decreases in protein and fiber. Children’s cereals contain high levels of added sugar, with a single serving exceeding 45% of the American Heart Association’s daily recommended limit for children. These trends suggest a potential prioritization of taste over nutritional quality in product development, contributing ...

About The Study: The older population (particularly male individuals and those living in high-sociodemographic index countries) is facing a substantial growing burden of skin cancer. Despite the relative incompleteness of keratinocyte cancer data and lack of race and ethnicity data, these results highlight the urgency for more effective prevention and management strategies targeting high-risk groups. Corresponding Author: To contact the corresponding author, Jin Chen, PhD, email chenjin7791@163.com. To access the embargoed study: Visit ...

A team of scientists has answered a long-standing question in cell biology, uncovering how the cell’s main energy currency, ATP, is transported into the endoplasmic reticulum (ER). Disrupted energy transport could affect diseases such as type 2 diabetes, cancer, and neurodegenerative disorders. The study, published in Nature, confirms that the transporter protein SLC35B1 is the key gateway for ATP entry into the ER. The research, led by David Drew, Professor of biochemistry at Stockholm University and located at SciLifeLab, reveals the first structural and mechanistic insight into how ATP enters the endoplasmic reticulum (ER) using ...

Researchers have demonstrated that by using a semiconductor with flexible bonds, the material can be moulded into various structures using nano containers, without altering its composition, the discovery could lead to the design of a variety of customised electronic devices using only a single element.  Semiconductors are vital to our daily lives, as they are found in nearly every electronic device. One of the key characteristics of semiconductors is their band gap, which determines how they conduct electric current. The band gap is typically ...

Living in a murky lake around Mexico City, surrounded by aggressive and cannibalistic neighbors, the axolotl lives at constant risk of losing a limb to a neighbor’s nibble. Fortunately, lost limbs regrow and are functional in as few as eight weeks. To achieve this feat, the regrowing body parts must “know” their position within the axolotl body to regenerate the right structure for a specific location. A long-sought code that tells the cells where they are located and thereby gives body parts their identity has now been cracked by Elly Tanaka and her group at IMBA, the Institute of Molecular Biotechnology ...

An international group of scientists has identified a key molecular process that drives a deadly form of childhood brain cancer, potentially offering a much-needed, new therapeutic target. Published in leading international journal Molecular Cell, the new study has revealed how a rare but devastating childhood brain cancer—called Diffuse Midline Glioma (DMG)—hijacks the cell’s gene control machinery to fuel its growth. The findings could point the way to urgently needed new treatments for this currently incurable disease. DMG is a tumour that develops deep in the brain and primarily ...

Embargoed for Release May 21, 2025 11am ET   CONTACT: NIH Office of Communications and Public Liaison NIHpress@nih.gov (301) 496-5787     Scientists design gene delivery systems for cells in the brain and spinal cord NIH-funded breakthrough could enable targeted therapies for many neurological disorders   Research teams funded by the National Institutes of Health (NIH) have created a versatile set of gene delivery systems that can reach different neural cell types in the human brain and spinal cord with exceptional accuracy. These delivery systems are a significant step toward future precise gene therapy to ...

In a study published in Nature today “Sequence diversity lost in early pregnancy,” scientists from deCODE genetics, a subsidiary of Amgen, estimate that around one in 136 pregnancies are lost due to new mutations in the fetus. In other words, millions of pregnancies worldwide are lost because of mutations every year. The human genome varies between individuals, but there are some locations in the genome where there seems to be little or no sequence variation between individuals. This raises the question whether the sequences at these locations are essential for human development? It is known that mutations ...

Background and objectives circPVT1 has emerged as a key regulator in disease progression and clinical outcomes. However, its prognostic relevance and association with clinicopathological parameters in solid malignancies remain to be fully elucidated. To address this, we conducted a meta-analysis to elucidate the clinical significance of circPVT1 in solid tumors. Methods A comprehensive literature search was conducted across multiple databases, including PubMed, Web of Science, Embase, the Cochrane Library, and CNKI, with a cutoff date of December 31, 2024. Statistical analyses were conducted using STATA 12.0 to calculate pooled hazard ratios (HRs) and ...