About The Study: This study identified 5.05% of individuals carrying pathogenic or likely pathogenic variants, suggesting a higher-than-expected prevalence of key cancer susceptibility genes in a large, unselected population. Corresponding Author: To contact the corresponding author, Joshua Arbesman, MD, email Arbesmj@ccf.org. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jama.2025.16372) Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support. #  ...

About The Study: In this cross-sectional study of U.S. medical students, Asian, Black, and Hispanic female medical students with disability (MSWD) were more likely to report general and race-based discrimination, whereas white and Asian female MSWD were more likely to report gender-based discrimination during medical school. These findings highlight the need to address intersecting forms of discrimination for medical students with disabilities.  Corresponding Author: To contact the corresponding author, Mytien Nguyen, MS, email mytien.nguyen@yale.edu. To access the embargoed study: Visit our For The Media website at this ...

About The Study: This study found that pickleball-related eye injuries have increased at an alarming rate over the past 4 years as the sport continues to grow in popularity. Eye protection is not currently mandated for casual or professional play. Establishing standardized guidelines for eye protection is recommended to reduce the risk of ocular injuries among players.  Corresponding Author: To contact the corresponding author, Jonathan C. Tsui, MD, email jonathan.tsui@va.gov. To access the embargoed study: Visit ...

Background and objectives A long-term high-fat diet (HFD) exerts lipotoxic effects on multiple organs, particularly the liver, leading to metabolic diseases. This study aimed to delineate the dynamic effects of HFD on lipid metabolism, elucidate the mechanisms underlying hepatic lipotoxicity, and investigate the protective effects of Ganoderma lucidum against lipotoxicity both in vitro and in vivo. Methods C57BL/6 mice were fed either a 45% or 60% HFD, followed by measurements of body composition, serum lipid profile, and liver pathology at four, eight, twelve, and sixteen weeks. Inflammatory responses, the unfolded ...

Chiral metal-organic frameworks (CMOFs) represent ideal platforms for circularly polarized luminescence (CPL). Incorporating rare-earth ions into MOFs enhances their luminescence via the antenna effect. Chiral imidazolium carboxylic ligands serve as excellent chiral building blocks for CMOFs. These ligands not only sensitize lanthanide ion emission through the antenna effect but also transfer chirality to the framework through coordination, enabling CPL. Their cationic nature imparts a positive charge to the framework channels, facilitating the immobilization of anionic guests through host-guest interactions. This enables modulation ...

Plastic waste management is a critical global challenge, with less than 10% of annual plastic production being recycled. Traditional methods like incineration and landfilling pose environmental risks, prompting scientists to explore photocatalytic alternatives. A team led by Prof. Zhi-Ming Zhang has now developed a groundbreaking Ni-POM@CdS catalyst that addresses this issue by coupling plastic waste (polylactic acid, PLA) degradation with hydrogen (H2) production—a clean energy source.   The team published their research result in Polyoxometalates on July 28, 2025.   This study reveals why the Ni-POM@CdS ...

The urgent demand for sustainable energy solutions faces a critical bottleneck: proton exchange membranes (PEMs) in high-temperature fuel cells (HT-FCs) struggle with rapid conductivity loss under anhydrous conditions above 100°C. Commercial perfluorosulfonic acid membranes fail in low humidity, while phosphoric acid-doped alternatives suffer from acid leakage, limiting efficiency and durability in next-generation energy devices.   A research team led by Kun Chen from the South China University of Technology pioneered a comb-like crosslinked polymer-polyoxometalate (POM) nanocomposite, integrating polymer with superacidic ...

A team from the the Universitat Jaume I (UJI) has developed an innovative robotic platform, powered by artificial intelligence, that promises to revolutionize the design of sustainable chemical processes. The system, named Reac-Discovery, makes it possible to optimize in just a few days what previously could take months or even years of work in a traditional laboratory, thanks to its high level of integration and automation. Chemistry and sustainability are advancing hand in hand. Reducing environmental impact while maintaining industrial ...

When biomedical researchers need to test their latest ideas, they often turn to engineered human tissue that mimics the responses in our own bodies. It’s become an important intermediary step before human clinical trials. One limiting factor: The cells need blood circulation to survive, and achieving that can be difficult in three-dimensional cell structures. Without proper vascular systems — even primitive ones — engineered tissue faces restricted size and functionality, even developing necrotic regions of dead cells. New research from Binghamton University’s Thomas ...

New York, NY (October 16, 2025) — The Mount Sinai Health System welcomes Elizabeth Haines, DO, MSc, FACEP, as Chief Operating Officer of Mount Sinai Kravis Children’s Hospital and Senior Vice President of Pediatric Services for the Mount Sinai Health System. Dr. Haines joins Mount Sinai with a distinguished career dedicated to advancing patient safety, quality, and operational excellence in pediatric health care. In her new role, she is providing strategic leadership and operational oversight to strengthen Mount Sinai’s mission of delivering world-class patient and family-centered care. She is responsible for guiding children’s health ...

People who feel supported by family, friends and colleagues tend to have better mental health, perform more effectively at work and experience positive outcomes in other areas such as physical health, education and risk-taking behaviors, according to research published by the American Psychological Association. “This study underscores the importance of considering the associations between multiple types and sources of perceived social support and multiple domains of human thriving,” said lead author GeckHong Yeo, PhD, of the National University of Singapore. “Our findings also suggest that adolescents, in particular, ...

Researchers at Tufts University School of Medicine and Tufts Graduate School of Biomedical Sciences have found a surprising connection between a fungus associated with alcohol use disorder and the brain’s dopamine reward pathway. Published October 16 in the journal mBio, the study describes, in mice, how an overgrowth of Candida albicans—a fungus that naturally resides in the human gut—increases levels of inflammatory molecules called PGE2 that can cross the blood-brain barrier and ...

Fukuoka, Japan—In the search for eco-friendly alternatives to synthetic herbicides, researchers from Kyushu University, Japan, have identified a potent, weed-inhibiting compound in the leaves of the Manchurian walnut tree (Juglans mandshurica Maxim.). The discovery of the compound, 2Z-decaprenol, and its unique mode of action on plants could lead to the development of more sustainable herbicides. The study was conducted in collaboration with researchers from Juntendo University in Japan and Chulalongkorn University in Thailand and was published ...

As cancer survivorship rises, many people living with or beyond cancer face lasting physical and emotional challenges – particularly anxiety and depression, which affect about 30% of this population. Emotional distress is often unspoken, leading to fear, despair, and diminished quality of life. Growing research highlights resilience – the ability to recover from adversity – is a key factor in helping individuals manage distress and improve well-being. This underscores the urgent need for health care providers to adopt a whole-person approach that supports not just the body, but also the emotional and psychological needs of people with cancer. As Breast Cancer Awareness ...

The pulp and paper industry consumes large amounts of energy. But despite stricter EU requirements for efficiency improvements, there has been no way to measure and compare energy consumption between different companies in a fair way. In collaboration with the Swedish Environmental Protection Agency, researchers at Linköping University, Sweden, now present a solution that has great potential to be used throughout the EU. “Even if this would contribute to increasing efficiency by one or a few per cent only, this involves so much energy that it can make a huge difference,” says Kristina Nyström, PhD student at the Department ...

Deep neural networks (DNNs), which power modern artificial intelligence (AI) models, are machine learning systems that learn hidden patterns from various types of data, be it images, audio or text, to make predictions or classifications. DNNs have transformed many fields with their remarkable prediction accuracy. Training DNNs typically relies on back-propagation (BP). While it has become indispensable for the success of DNNs, BP has several limitations, such as slow convergence, overfitting, high computational requirements, ...

Tiny airborne particles known as aerosols, from biomass burning, urban pollution, and industrial emissions, can dramatically alter rainfall, cloud formation, and atmospheric stability. A new study led by Professor Kyong-Hwan Seo of Pusan National University, Korea, shows that aerosols profoundly reshape precipitation over the Maritime Continent, a region including Indonesia, Malaysia, Singapore, Vietnam, Thailand, the Philippines, and surrounding seas, where millions rely on predictable rainfall for water, food, and flood protection. Published online in npj Climate and Atmospheric ...

Orthodontic treatment is most effective when timed to coincide with a child’s growth peak. Traditionally, clinicians estimate growth by examining X-ray images of the cervical vertebrae—the neck bones visible in routine dental radiographs. However, this process requires careful manual annotation of specific points on the bones, a task that is both time-consuming and prone to variation between observers. In a new article, researchers from Korea University Anam Hospital, KAIST, and the University of Ulsan introduced an artificial intelligence (AI) system designed to overcome these challenges. The paper was made available online on 29 July 2025 and published ...

With the rise of quantum computers, the security of our existing communication systems is at risk. Quantum computers will be able to break many of the encryption methods used in current communication systems. To counter this, scientists are developing quantum communication systems, which utilize quantum mechanics to offer stronger security. A crucial building block of these systems is a single-photon source: a device that generates only one light particle at a time. These photons, carrying quantum information, are then sent through optical fibers. For quantum communication systems to work, it is essential ...

RICHLAND, Wash. — New research has found cover crops that are viable in Washington’s normal “off season” don’t hurt the soil and can be sold as a biofuel source.  After harvest, farmland often sits fallow and unused until growers seed in the next crop. Soil can erode, weeds can take root, and farmers don’t make any money during that time. Cover crops can eliminate or reduce some of those issues, but many farmers have concerns about their effects on soil quality, a reduced growing window for their primary crop, and the inability to sell ...

A study published in Environment International concludes that air pollution during pregnancy is associated with slower brain maturation in newborns. It is the first study to analyze brain development within the first month of life and stems from the collaboration between researchers at Hospital del Mar, the Barcelona Institute for Global Health (ISGlobal) —a center promoted by the “la Caixa” Foundation—, and the CIBER area of Epidemiology and Public Health (CIBERESP). Myelination is a key process in brain maturation, in which myelin coats neuronal connections ...

Expanding farming capabilities will not close Africa’s ‘hidden hunger’ gaps Researchers combined data on demand, production, and resource constraints, moving beyond calories to nutrients that matter for health across all 54 African countries   ‘Hidden hunger’ in Africa cannot be addressed by expanding domestic farming alone, according to a new study from Cardiff University. The first-of-its-kind assessment, published in Nature Food, moves beyond calories to measure the availability of nutrients that matter for health, across all 54 African countries.  According to the research, limited land and water supply ...

A glittering hunk of crystal gets its iridescence from a highly regular atomic structure.  Frank Wilczek, the 2012 Nobel Laureate in Physics, proposed quantum systems –– like groups of particles –– could construct themselves in the same way, but in time instead of space. He dubbed such systems time crystals, defining them by their lowest possible energy state, which perpetually repeats movements without external energy input. Time crystals were experimentally proved to exist in 2016. Now researchers at Aalto University’s Department of Applied Physics have, for the first time, connected a time crystal to another ...

A new study published in the journal Nature Communications reveals that the El Niño-Southern Oscillation (ENSO), a key driver of global climate variability, is projected to undergo a dramatic transformation due to greenhouse warming. Using high-resolution climate models (Figure 1), a team of researchers from South Korea, the USA, Germany, and Ireland found that ENSO could intensify rapidly over the coming decades and synchronize with other major climate phenomena, reshaping global temperature and rainfall patterns by the end of the 21st century. The study projects an abrupt shift within the next 30-40 years from irregular El Niño-La ...

Quantum radio antenna A team from the Faculty of Physics and the Centre for Quantum Optical Technologies at the University of Warsaw has developed a new type of all-optical radio receiver based on the fundamental properties of Rydberg atoms. The new type of receiver is not only extremely sensitive, but also provides internal calibration, and the antenna itself is powered only by laser light. The results of the work, in which Sebastian Borówka, Mateusz Mazelanik, Wojciech Wasilewski and Michał Parniak participated, were published in the prestigious journal Nature Communications. They open a new chapter ...