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Sex differences in gambling rats

2025-11-03
Some people with psychiatric conditions, including addiction and attention deficit hyperactivity disorder, struggle to control their urges or make decisions under uncertainty. In a collaboration between the University of Cambridge and the University of British Columbia, Tristan Hynes and colleagues used rats to explore the role of a specific reward-related neuron population in shaping impulsivity and risky decision-making during a gambling task.  As reported in their JNeurosci paper, the researchers manipulated the neuron population’s activity as rats chose between ...

From charged polymers to life-saving innovations

2025-11-03
Whether natural or synthetic, polymers — large molecules made up of repeating units called monomers — exhibit complex structures and properties that make them useful in a wide range of applications. In their soft, nearly liquid biogel form, polymers viewed through an optical microscope resemble a bowl of tangled soft noodles. In that state, they tend to coacervate, or combine, with other polymers — when those polymers carry opposite electrostatic charges.    UC Santa Barbara ...

Building a safer future: 40+ experts chart roadmap to reduce firearm harms by 2040

2025-11-03
JAMA EMBARGOED FOR RELEASE: 11:05 AM (ET) MONDAY, NOVEMBER 3, 2025 To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ Embed this link to provide your readers free access to the full-text article. This link will be live at the embargo time: https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2025.18076?guestAccessKey=aa261df0-fa34-4202-9144-5bce85b8661a&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=110325  CHICAGO, IL — Since the start of the 21st century, ...

Society for Neuroscience 2025 early career scientists’ achievements and research awards

2025-11-03
SAN DIEGO — The Society for Neuroscience (SfN) will honor seven early career researchers whose awards will be presented during Neuroscience 2025, SfN's annual meeting. “Innovative thinking often comes from those just beginning their scientific journeys,” said SfN President John H. Morrison. “These early career researchers are advancing neuroscience through breakthroughs in nanoscale imaging, new computational methods, neuroplasticity, and more.” Jennifer N. Bourne Prize in Neuronal and Synaptic Structure and Function: Gregg Wildenberg The Jennifer N. Bourne Prize in Neuronal and Synaptic Structure and ...

Society for Neuroscience 2025 Education and Outreach Awards

2025-11-03
SAN DIEGO – The Society for Neuroscience (SfN) will present eight individuals and groups with this year’s Science Education and Outreach Awards, comprised of the Award for Education in Neuroscience, the Science Educator Award, the Next Generation Awards, and the Chapter of the Year Awards. The awards will be presented during SfN’s annual meeting. “The Society is honored to recognize these compassionate and creative neuroscientists who are helping to serve underrepresented communities and educate the public,” said SfN President John H. Morrison. “Their work expands access to neuroscience education for populations that historically lacked such opportunities, ...

Society for Neuroscience 2025 Outstanding Career and Research Achievement Awards

2025-11-03
SAN DIEGO – The Society for Neuroscience (SfN) will honor five leading researchers whose impactful work has transformed neuroscience — including the understanding of memory, synapse formation, social reinforcement in addiction, and how neurons make sense of input noise — with this year’s Outstanding Career and Research Achievement Awards. The awards will be presented during SfN’s annual meeting. “The Society is honored to recognize this year’s awardees, whose pioneering work has shaped the field and led to paradigm shifts in ...

Society for Neuroscience 2025 Promotion of Women in Neuroscience Awards

2025-11-03
SAN DIEGO — The Society for Neuroscience (SfN) will honor six researchers who have made significant contributions to the advancement of women in neuroscience. The awards will be presented during Neuroscience 2025, SfN's annual meeting. "Science thrives as a vibrant network of individuals committed to advancing it,” said SfN President John H. Morrison. “These awardees push the boundaries of neuroscience through their own work while uplifting and empowering others, who will in turn shape the future of the neuroscience community." Bernice Grafstein Award for Outstanding Accomplishments in Mentoring: David Poeppel The Bernice Grafstein Award ...

Kids First releases landmark dataset on rare childhood germ cell tumors

2025-11-03
The Gabriella Miller Kids First Data Resource Center (Kids First DRC) has released its 37th pediatric research study, available in the Kids First Data Resource Portal. This latest study focuses on extracranial germ cell tumors, a rare group of childhood cancers that can develop outside of or within the brain. WHO: Kids First, a program from the National Institutes of Health (NIH) WHAT: Announcing the latest data release to the Kids First data ecosystem, the Kids First: Extracranial Germ Cell Tumors study (KF-ECGT). This new dataset comprises information from 393 children and young adults, along with a total of 493 biological ...

Lichens and drones reveal dinosaur bones

2025-11-03
Vibrant orange-coloured lichens are helping scientists discover dinosaur fossils in Canada, according to a new study published today [3 November] in Current Biology. An international team of palaeontologists and remote sensing scientists have made an exciting discovery at UNESCO World Heritage Site Dinosaur Provincial Park, in Alberta. They have found that certain lichen species preferentially colonise exposed dinosaur bones, creating distinctive spectral signatures that can be detected from 30 metres above ground using drones. Dr Brian ...

Even modest amounts of physical activity may slow Alzheimer’s disease among at-risk older adults

2025-11-03
Increasing your steps by even a little bit may help slow down the progression of Alzheimer’s disease among people at heightened risk, according to a new study. In a paper published in Nature Medicine, Mass General Brigham researchers found that physical activity was associated with slower rates of cognitive decline in older adults with elevated levels of amyloid-beta, a protein associated with Alzheimer’s. Cognitive decline was delayed by three years on average for people who walked just 3,000-5,000 steps per day, and by seven years in people who walked 5,000-7,500 steps per day. Sedentary individuals had a significantly faster buildup of ...

OHSU researchers identify new tools for early cancer detection, treatment

2025-11-03
Scientists are exploring leading-edge technologies that could transform how cancer is studied, detected and treated by catching it earlier, when it’s more treatable and survival rates are highest. A new review by researchers at Oregon Health & Science University’s Knight Cancer Institute and other universities highlights how advances in New Approach Methodologies and tissue engineering are offering powerful new tools to study the earliest stages of cancer development. New Approach Methodologies use human-relevant technologies such as in vitro tests, organoids, organs-on-a-chip and computational modeling to replace, reduce or refine ...

Trends in daily nicotine vaping and unsuccessful quit attempts in youths

2025-11-03
About The Study: The findings of this study suggest that the U.S. youth nicotine vaping population recently became increasingly represented by daily use and unsuccessful quit attempts, a trend of which clinicians and policy makers should be aware.  Corresponding Author: To contact the corresponding author, Abbey R. Masonbrink, MD, MPH, email amasonbrink@chla.usc.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2025.41061) Editor’s Note: Please see the article for additional information, ...

Childhood adversity and all-cause mortality risk

2025-11-03
About The Study: This study found that exposure to childhood adversity was associated with elevated all-cause mortality risk among adults with diabetes, hypertension, or mild-to-moderate emergency department visits.  Corresponding Author: To contact the corresponding author, Ping-I Lin, MD, PhD, email daniel.lin@health.slu.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamapediatrics.2025.4285) Editor’s Note: Please see the article for additional information, including other authors, author contributions ...

Among youth who vape, USC study finds rise in daily use and difficulty quitting

2025-11-03
Since 2019, overall rates of nicotine vaping have declined among U.S. youth, but those who continue to vape are showing signs of worsening addiction, according to new USC research. Between 2020 and 2024, the share of current users who vaped every day increased from 15.4% to 28.8%. Over the same period, the share of daily users who tried to quit but were unable to rose from 28.2% to 53%. The study, funded in part by the National Institutes of Health, was just published in JAMA Network Open. Public health advocates raised the alarm when youth vaping rates surged between 2014 and 2019. Data collected during the COVID-19 ...

Antarctic glacier retreated faster than any other in modern history

2025-11-03
A glacier on Antarctica’s Eastern Peninsula experienced the fastest retreat recorded in modern history—in just two months, nearly 50 percent of the glacier disintegrated.  A new CU Boulder-led study, published today in Nature Geoscience, details how and why Antarctica’s Hektoria Glacier retreated at an unprecedented rate in 2023, losing a total of eight kilometers of ice in two months. The main driver was the glacier's underlying flat bedrock that enabled the glacier to go afloat after it substantially thinned, causing a rare calving process.  The new findings may help researchers identify other glaciers to monitor for rapid ...

Unraveling cancer’s neural connections: NIH-funded study investigates how stem cell regulation influences tissue renewal and cancer development

2025-11-03
The same cellular renewal that keeps our bodies healthy might also fuel the growth of cancer. A UC Merced biologist has found that the brain could hold the key to stopping it. Professor Néstor Oviedo, a molecular and cell biologist and affiliate of the Health Sciences Research Institute, received more than $2 million from the National Institutes of Health to investigate signals mediating the earliest stages of cancer development. His findings could one day change how doctors think about treating cancer and age-related diseases. “Our initial data suggest that key cancer symptoms can be selectively removed by activating signals from the nervous system,” ...

Lightweight multi-wavelength network model for efficient and high-fidelity full-color 3D holographic display

2025-11-03
Computer-generated holography (CGH), as one of the most attractive next-generation three-dimensional (3D) display technology, possesses the capacity to provide authentic depth cues of 3D scenes via faithfully recording the optical field with computational simulations and loading the calculated holograms to reconstruct the target scenes. However, the process of hologram generation is predominately an ill-posed inverse problem, since only the intensity or amplitude information of the target scene is known while the original wavefront phase remains inaccessible ...

Halide perovskite volatile unipolar Nanomemristor

2025-11-03
The last experimentally fundamental passive circuit element is the memristor that was originated in 2008 by Dmitri Strukov and presents a thin-film dielectric material with oxygen vacancies placed between two electrodes. This element changes its resistance based on the amount and direction of current that has flowed through it and its resistance has non-linear behavior from the current flow. Memristors are used in neuromorphic computing, data storage systems, and various devices for information processing and consume less power than basic silicon transistors. These elements are an attractive subject for modern scientific community due to their advantages ...

New foundation model reveals how cells are organized in tissues

2025-11-03
Missing Context in Single-Cell Data Single-cell RNA sequencing has transformed biology by showing which genes are active in individual cells. However, this approach requires cells to be removed from their natural environment, erasing information about their position and neighbors. Spatial transcriptomics preserves this context but is technically more limited and harder to scale. Researchers have long lacked a way to study cell identity and tissue organization together. AI Model Reveals Hidden Tissue Structures Nicheformer overcomes this barrier by learning from both dissociated and spatial data. It can “transfer” spatial context back onto cells that were previously ...

Printing with fields: Reprogramming matter at the smallest scales

2025-11-03
From medical microrobots to flexible sensors, the next generation of technology depends on devices that are smaller, smarter, and more capable than ever before. But building these intricate structure, often just micrometers across, requires extraordinary precision, not only in shaping materials but in programming their properties. In the International Journal of Extreme Manufacturing, a team of Chinese researchers reviews the fast-growing field of Field-assisted Additive Manufacturing (FAM)—a method that combines 3D printing with external fields such as magnetic, acoustic, or electric stimuli to precisely guide materials as they form. "Traditional ...

Reimagine biocatalysis: Turning DNA phosphates into chiral catalysts

2025-11-03
Chemists at the National University of Singapore (NUS) have found a new use for deoxyribonucleic acid (DNA), not just as genetic material, but as a tool for more efficient production of medicinal compounds. Certain parts of DNA, called phosphates, can act like tiny “hands” that guide chemical reactions to selectively produce the desired mirror-image version of a compound. Many medicinal compounds are chiral, meaning they come in two mirror-image forms, like right and left hands, that can behave very differently in the body. This is an important aspect because many drugs only work in ...

Potential of new materials for absorbing 99.5% of light on solar towers demonstrated at the EHU

2025-11-03
Renewable energy of the future is concentrated solar power because it can be easily used to store thermal energy. Despite the fact that, historically, it is more expensive and complex than photovoltaic power, in recent years huge advances have taken place in this technology, and concentrated solar power plants are spreading across more and more countries as a source for a sustainable future. As Iñigo González de Arrieta, a researcher in the Thermophysical Properties of Materials group of the University of the Basque ...

Dr. Xin Jin named 2026 Peter Gruss Young Investigator

2025-11-03
In recognition of her innovative experimental approaches and breakthrough discoveries on the genetic mechanisms of neurodevelopmental disorders, Dr. Xin Jin has been named the 2026 Peter Gruss Young Investigator. “The field of nominees was incredibly impressive; however, Dr. Jin stood out among the nominees for her creative and multidisciplinary integration of methodologies to make tremendous progress toward understanding principles of brain development and function. She is well on her way to becoming a leader in the neuroscience field,” ...

New antibody therapy reawakens immune system to fight pancreatic cancer

2025-11-03
Pancreatic cancer is one of the deadliest cancers, often diagnosed late and resistant to treatment Scientists discovered a new sugar-based cloak that helps tumor cells evade the immune system An experimental antibody blocked that disguise, reawakening immune cells and slowing tumor growth in mice Northwestern team is now refining the antibody for human studies CHICAGO --- Pancreatic cancer is notoriously hard to treat and often resists the most advanced immunotherapies. Northwestern Medicine scientists have uncovered a novel explanation for that resistance: Pancreatic ...

David B. Allison, PhD (Baylor College of Medicine), Lauren Hunt PhD, RN, FNP (UCSF), and Arlan Richardson, PhD (University of Oklahoma Health Sciences) to be honored with AFAR annual scientific Awards

2025-11-03
New York, NY and Boston, MA -- The American Federation for Aging Research (AFAR), a national non-profit whose mission is to support and advance healthy aging through biomedical research, will host its annual Scientific Awards of Distinction ceremony in conjunction with the Annual Scientific Meeting of the Gerontological Society of America (GSA), on November 13, 2025 from 6:30pm-9:00pm ET in Room 306 of the Hynes Convention Center in Boston, Massachusetts. AFAR Scientific Director Steven N. Austad, PhD, will host ...
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