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Mount Sinai researchers find electrical stimulation may help predict recovery path for acute nerve injuries

2025-09-12
Journal: Clinical Orthopaedics and Related Research Title: Is a Response to Intraoperative Electrical Nerve Stimulation Associated with Recovery After Stretch Injury in the Rat Median Nerve? Authors: Paul J. Cagle, MD, Associate Professor of Orthopedics (Shoulder and Elbow Surgery), Associate Residency Program Director, and Chief of Quality Assurance at Mount Sinai West in the Leni and Peter W. May Department of Orthopedic Surgery Michael R. Hausman, MD, Dr. Robert K. Lippmann Professor of Orthopaedics, Vice Chair of Orthopedics, and Chief of Hand and Upper Extremity Surgery for the Mount Sinai Health ...

Developmental biologist Maria Jasin wins the 2025 Pearl Meister Greengard Prize

2025-09-12
Maria Jasin, whose fundamental research on repair of damaged DNA in cells has transformed our understanding of cancers linked to inherited gene mutations, has been selected as the 2025 recipient of the Pearl Meister Greengard Prize. Awarded annually by Rockefeller University, the prize is the preeminent international award recognizing outstanding women scientists. Jasin, an investigator at Memorial Sloan Kettering Cancer Center and the Weill Cornell Graduate School of Medical Sciences, will be honored at a ceremony on campus on September 16. She will be presented with the award by architect Wendy Evans Joseph, the founder of Studio Joseph who is known ...

Training doctors for the digital age: Canadian study charts new course for health education

2025-09-12
(Toronto, September 12, 2025) As Canada’s health care system rapidly adopts digital technologies, a group of Canadian researchers is calling for a major overhaul of health professional education to ensure consistent, outcomes-based training in digital health and informatics competencies. A new article published in JMIR Medical Education by researchers at the British Columbia Institute of Technology and University of Calgary proposes using the Quintuple Aim as a national guiding framework to prioritize the digital health skills health care workers need now and in the future. The paper, titled “Shaping the Future of Digital Health Education in Canada: Prioritizing ...

New College of AI, Cyber and Computing launched at UT San Antonio

2025-09-12
(SAN ANTONIO, TEXAS) -- The University of Texas at San Antonio launched the College of AI, Cyber and Computing on Sept. 1 bringing together academic programs in artificial intelligence, cybersecurity, computing and data science. The new college positions UT San Antonio at the forefront of technological education and research and brings the number of academic colleges at UT San Antonio to nine. Formation of the college began during a multi-phase process in January 2024 with the announcement of a university-wide initiative to elevate the university’s leadership in emerging technologies. Shaped by input across campus and community partners, the effort included a dedicated ...

Collaborative team earns five-year renewal grant from NINDS to continue stroke research

2025-09-12
Stroke research aims to understand the brain’s self-protective and repair mechanisms. Gaining detailed insight into these mechanisms is crucial as such knowledge could lead to newly developed medications and interventions which mimic or engage the brain’s self-protective/repair mechanisms, leading to innovative stroke therapies. In 2018 the National Institute of Neurological Disorders and Stroke (NINDS) at the National Institutes of Health (NIH) awarded a five-year, $2.9 million R01 grant (“Development ...

Vitamin K analogues may help transform the treatment of neurodegenerative diseases

2025-09-12
Neurodegenerative diseases like Alzheimer’s, Parkinson’s, and Huntington’s disease are characterized by the progressive loss of neurons. The resulting debilitating symptoms, such as loss of memory and cognition, and motor impairment, can significantly degrade patients’ quality of life, confining them to round-the-clock care. While currently used drugs help alleviate symptoms, curative treatments are lacking, thus underscoring the need for novel therapeutic strategies. One such strategy involves the induction of neuronal differentiation, which can replenish lost neurons and ...

Cyclic triaxial tests: Evaluation of liquefaction resistance in chemically treated soils

2025-09-12
Soil liquefaction can be a major threat to the infrastructure and built environments in an earthquake-prone area. This happens due to substantial loss of soil stiffness and strength due to applied stress. Loose, moderately granulated, sandy soil is more prone to soil liquefaction. Recognizing the urgent need to enhance urban resilience in seismic-prone regions, particularly in rapidly urbanizing areas vulnerable to such hazards, scientists are focusing on different mitigation techniques. Soil compaction technique ...

Uniting the light spectrum on a chip

2025-09-12
Focused laser-like light that covers a wide range of frequencies is highly desirable for many scientific studies and for many applications, for instance quality control of manufacturing semiconductor electronic chips. But creating such broadband and coherent light has been difficult to achieve with anything but bulky energy-hungry tabletop devices. Now, a Caltech team led by Alireza Marandi, a professor of electrical engineering and applied physics at Caltech, has created a tiny device capable of producing an unusually wide range of laser-light ...

Hundreds of new bacteria, and two potential antibiotics, found in soil

2025-09-12
Most bacteria cannot be cultured in the lab—and that’s been bad news for medicine. Many of our frontline antibiotics originated from microbes, yet as antibiotic resistance spreads and drug pipelines run dry, the soil beneath our feet has a vast hidden reservoir of untapped lifesaving compounds. Now, researchers have developed a way to access this microbial goldmine. Their approach, published in Nature Biotechnology, circumvents the need to grow bacteria in the lab by extracting very large DNA fragments directly from soil to piece together the genomes of previously hidden microbes, and then mines resulting genomes for ...

Smells deceive the brain – are interpreted as taste

2025-09-12
Flavoured drinks without sugar can be perceived as sweet – and now researchers know why. A new study from Karolinska Institutet in Sweden, published in the journal Nature Communications, reveals that the brain interprets certain aromas as taste. When we eat or drink, we don’t just experience taste, but rather a ‘flavour’. This taste experience arises from a combination of taste and smell, where aromas from food reach the nose via the oral cavity, known as retronasal odour. Researchers at Karolinska Institutet have now shown that the brain integrates these signals earlier than previously thought – already in the insula, ...

New species survival commission fills critical gap in conservation

2025-09-12
A newly-formed group of scientists will be fighting for the survival of species — the smallest ones on the planet.   The International Union for Conservation of Nature (IUCN) has launched a species survival commission for microbiology and microbes to serve as a global safeguard for microbial biodiversity and to pursue coordinated conservation action. The new Microbial Conservation Specialist Group marks a first in the history of international conservation and filling a critical gap in ...

New conservation committee led by Applied Microbiology International calls on science community to get on board with microbial conservation

2025-09-12
The team behind a new world-leading conservation committee headed by Applied Microbiology International (AMI) is calling on global scientific and conservation communities to get on board to protect microbial life. Members of the new IUCN Microbial Conservation Specialist Group (MCSG) have outlined its priorities for its first year and beyond in a paper published in Nature Microbiology. Earlier this year, global conservation leader, the International Union for the Conservation of Nature (IUCN) officially approved ...

Scientists uncover key stabilizing role of small molecules

2025-09-12
For decades, amino acids have been added to medical formulations like insulin as stabilizers: these small molecules keep proteins (i.e. larger particles) from interacting in undesirable ways. And for decades, scientists have known that this works – but not why. Now, an international team of scientists, led by the Supramolecular Nano-Materials and Interfaces Laboratory in EPFL’s School of Engineering, has finally explained the ‘why’ – and in the process, unearthed a fundamental stabilizing effect ...

“Black Hole Stars” could solve JWST riddle of overly massive early galaxies

2025-09-12
In the summer of 2022, less than a full month after the James Webb Space Telescope (JWST) had begun to produce its first scientific images, astronomers noticed something unexpected: little red dots. In pictures taken at JWST’s unprecedented sensitivity, these extremely compact, very red celestial objects showed very clearly on the sky and there appeared to be a considerable number of them. JWST had apparently discovered a whole new population of astronomical objects, which had eluded the Hubble Space Telescope. That latter part is unsurprising. “Very red” ...

Mysterious ‘red dots’ in early universe may be ‘black hole star’ atmospheres

2025-09-12
UNIVERSITY PARK, Pa. — Tiny red objects spotted by NASA's James Webb Space Telescope (JWST) are offering scientists new insights into the origins of galaxies in the universe — and may represent an entirely new class of celestial object: a black hole swallowing massive amounts of matter and spitting out light. Using the first datasets released by the telescope in 2022, an international team of scientists including Penn State researchers discovered mysterious “little red dots.” The researchers suggested the objects may be galaxies that were as mature as our current Milky Way, which is roughly 13.6 billion years ...

A gene mutation found in East Asian people increases liver disease risk by an ‘aldehyde storm’

2025-09-12
Researchers have identified the mechanism by which a common genetic mutation increases liver disease risk. Their findings suggest that healthy choices, such as increasing antioxidants and limiting exposure to smoke, may reduce the risk of this disease. Aldehyde dehydrogenase 2 (ALDH2) is an important enzyme that detoxifies harmful aldehydes produced in the body. While it is best known for metabolizing acetaldehyde –an aldehyde increased by drinking– it also plays a role in detoxifying other harmful aldehydes, including acrolein. Acrolein is a highly reactive aldehyde produced by environmental exposure to pollutants such as cigarette smoke. It damages proteins, DNA, and lipids, ...

Artificial intelligence‑assisted conductive hydrogel dressings for refractory wounds monitoring

2025-09-12
As chronic wounds such as diabetic ulcers, pressure ulcers, and articular wounds continue to challenge global healthcare systems, a team of researchers from China has introduced a promising innovation: AI-integrated conductive hydrogel dressings for intelligent wound monitoring and healing. This comprehensive review, led by researchers from China Medical University and Northeastern University, outlines how these smart dressings combine real-time physiological signal detection with artificial intelligence, offering a new paradigm in personalized wound care. Why It Matters: Real-Time Monitoring: Conductive hydrogels can track key wound ...

Scalable fabrication of methylammonium‑free wide‑bandgap perovskite solar cells by blade coating in ambient air

2025-09-12
Wide-band-gap perovskites are the key top-cell for >30 % tandem modules, yet spin-coating and methylammonium (MA) instability block factory-scale production. Now researchers from Southwest Petroleum University, UNSW and UCL have formulated an MA-free ink that can be blade-coated in ambient air and delivers certified 23 % efficiency—one of the highest values ever reported for a 1.69 eV MA-free film. Why This Matters Air-processable: 23 % small-area cell and 20.2 % 10.5 cm2 mini-module fabricated entirely in room air—no glove-box. MA-free stability: eliminates MA cation de-protonation and proton migration, ...

Wearable devices could revolutionize pregnancy monitoring and detect abnormalities

2025-09-12
LA JOLLA, CA— A simple fitness tracker might hold the key to revolutionizing maternal healthcare. Scientists at Scripps Research have found preliminary evidence suggesting that common wearable devices such as the Apple Watch, Garmin and Fitbit could remotely monitor pregnancy-related health changes by tracking physiological patterns—like heart rate—that correlate with hormonal fluctuations. “Wearable devices offer a unique opportunity to develop innovative solutions that address the high number of adverse pregnancy outcomes ...

Efficient cation recognition strategies for cationic compounds

2025-09-12
Huang Feihe at Zhejiang University, Jonathan Sessler of the University of Texas at Austin, and colleagues reported a novel cation recognition mode which mimics the biological allosteric effect and achieves efficient recognition of cations by cationic compounds. Specifically, this work achieves continuous recognition of anions and cations by synergizing various recognition modes while also utilizing the allosteric effect during the recognition process to explore a new cation recognition mode. Background: Coulomb's ...

US COVID-19 school closures were not cost-effective, but other non-pharmaceutical interventions were, new study finds

2025-09-12
School closures during the COVID-19 pandemic imposed enormous long-term costs while other measures delivered better health outcomes for far less money, according to new research led by Oxford University's Department of Statistics and the Leverhulme Centre for Demographic Science analysing non-pharmaceutical interventions in the United States. The study, published in BMC Global and Public Health, examined policies implemented across US states during 2020, before vaccines became available. Researchers from Oxford and the University of Washington analysed ...

Human activities linked to declines of big seeds

2025-09-12
Seeds in Madagascar’s forests are getting smaller, and new research published in Ecology Letters suggests that human activities are playing a role in this shift. Researchers from the German Centre for Integrative Biodiversity Research (iDiv) and Leipzig University combined data from more than 2,800 plant species, 48 living and 15 extinct fruit-eating animals (frugivores) – including birds and lemurs. The results show that both past human-driven frugivore extinctions and current human pressures are shaping seed size across the island. The researchers found that increased human footprint (a cumulative index of human pressure) is associated ...

North-south autism assessment divide leaves children waiting three years longer 

2025-09-11
Children in the North of England are waiting up to three years longer than those in the south for an autism diagnosis, new data analysis shows.  The data, released by NHS England, reveals that children in Mid and South Essex are waiting on average 54 days for an assessment – falling within National Institute for Health and Care Excellence (NICE) guidelines of 13 weeks.   However, in South Yorkshire, children wait on average 1,063 days – almost three years longer.  Published today by the Child of the North initiative, the data also shows:  only ...

Want to publish in Nature? Webinar with Prof. Willie Peijnenburg shares insider tips

2025-09-11
Many researchers dream of publishing their work in world-leading journals like Nature. But how do you catch the attention of editors and reviewers at such high-impact publications? On Sunday, September 14, 2025, an international online webinar will bring answers straight from the source. Prof. Willie Peijnenburg, a distinguished environmental scientist from Leiden University in the Netherlands, will share practical strategies on how to write and present research that makes it into top-tier journals. Prof. Peijnenburg has authored more than 675 scientific ...

Cataract surgery on both eyes can be carried out safely and effectively in one go

2025-09-11
Copenhagen, Denmark: The results of two new studies show that it can be safe, effective and practical for most patients to have cataract surgery on both eyes in one day. Both studies will be presented at the 43rd Congress of the European Society of Cataract and Refractive Surgeons (ESCRS).   The first study [1], by Danish researchers, shows that the majority of patients can manage at home on their own after cataract surgery on both eyes, and carry out essential tasks such as preparing food and using their mobile phone.   The ...
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