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Veterans with cardiometabolic conditions face significant risk of dying during extreme heat events

2025-11-25
Veterans living in California who have cardiometabolic conditions such as diabetes and high blood pressure experience significantly higher risk of dying during heat waves compared to cooler days, UCLA-led research finds. The study, to be published in the peer-reviewed JAMA Network Open, demonstrates the danger that heat waves can pose for people with heart disease and risk factors for heart disease, whether or not they are veterans, said Dr. Evan Shannon, assistant professor-in-residence at the David Geffen School of Medicine at UCLA and the study’s lead author. Veterans are particularly vulnerable to these heat events because they tend to be older, ...

How plants search for nutrients

2025-11-25
What makes plants tolerant to nutrient fluctuations? An international research team led by the Technical University of Munich (TUM) and involving the Leibniz Institute of Plant Genetics and Crop Plant Research (IPK) has investigated this question on the micronutrient boron. The researchers analyzed 185 gene data sets from the model plant Arabidopsis. Their goal is to then be able to transfer the findings to the important crop plant rapeseed. Boron is one of the key micronutrients for the growth and fertility of many plants. However, extreme weather events reduce the availability of this nutrient: drought reduces boron uptake, ...

Prefrontal cortex reaches back into the brain to shape how other regions function

2025-11-25
Vision shapes behavior and, a new study by MIT neuroscientists finds, behavior and internal states shape vision. The research, published Nov. 25 in Neuron, finds in mice that via specific circuits, the brain’s executive control center, the prefrontal cortex, sends tailored messages to regions governing vision and motion to ensure that their work is shaped by contexts such as the mouse’s level of arousal and whether they are on the move. “That’s the major conclusion of this paper: There are targeted projections for targeted ...

Much-needed new drug approved for deadliest blood cancer

2025-11-25
Biomedical research that began at the University of Virginia School of Medicine has yielded a much-needed new treatment for patients with the deadliest form of blood cancer. The federal Food and Drug Administration has approved the drug ziftomenib for patients with recurring or treatment-resistant acute myeloid leukemia who have a mutation in the NPM1 gene. The new medication, taken by mouth once daily, offers a potential treatment for patients who otherwise have no good options. The drug arose from many years of research by Jolanta Grembecka, PhD, and Tomasz Cierpicki, PhD, who began the ...

American College of Lifestyle Medicine publishes official position on lifestyle medicine as a framework for delivery of high-value, whole-person care

2025-11-25
The American College of Lifestyle Medicine (ACLM) has published a position paper calling for the implementation of lifestyle medicine as a high-value care solution that delivers on the Quintuple Aim—better health outcomes, higher patient and clinician satisfaction, greater health equity, and lower costs. The paper includes five position statements asserting that lifestyle medicine—a rapidly growing medical specialty focused on evidence-based lifestyle interventions to treat, reverse and prevent chronic disease—offers a scalable and sustainable approach to address the nation’s ...

Hospital infections associated with higher risk of dementia

2025-11-25
BUFFALO, NY — November 25, 2025 — A new research paper was published in Volume 17, Issue 10 of Aging-US on October 13, 2025, titled “Hospitalization with infections and risk of Dementia: a systematic review and meta-analysis.” This large-scale meta-analysis, led by first author Wei Yu Chua from the National University of Singapore and corresponding author Eng-King Tan from the National Neuroscience Institute and Duke-NUS Medical School in Singapore, shows that adults hospitalized ...

Thyroid dysfunction during pregnancy may increase autism risk in children

2025-11-25
WASHINGTON—Women with persistent thyroid hormone imbalance across pregnancy may be at an increased risk of having children with autism, according to a new study published in The Journal of Clinical Endocrinology & Metabolism. Maternal thyroid hormones are essential for fetal neurodevelopment. Gestational thyroid imbalance has been associated with atypical neurodevelopment, including increased risk of autism spectrum disorder (ASD). Autism is a complex neurodevelopmental condition that affects how a person communicates, interacts with others and experiences the world. “We ...

Cross-national willingness to share

2025-11-25
Global challenges necessitate cooperation beyond national borders. Prosociality—the tendency to share with and value the outcomes of others—can help achieve this objective. While it is well-established that people favor their own compatriots, people also display substantial prosociality toward individuals from other nations, though not all foreigners are treated equally. Vanessa Clemens and colleagues invited 6,182 participants from 25 nations to take part in a sharing game with individuals from each of the participating nations. Each person received 150 “Talers” — a made-up currency — and chose between different ways of sharing the ...

Seeing rich people increases support for wealth redistribution

2025-11-25
If people do not observe inequality, they are less likely to favor policies that redistribute wealth, such as taxation—but they are also more satisfied with their lot, according to online experiments involving 1,440 US-based participants. Milena Tsvetkova and colleagues developed a model simulating how network structure affects perception of inequality and tested its predictions through an online experiment where participants voted on tax rates. In the experiment, participants were randomly assigned as "rich" (with scores around ...

How personalized algorithms lead to a distorted view of reality

2025-11-25
The same personalized algorithms that deliver online content based on your previous choices on social media sites like YouTube also impair learning, a new study suggests.   Researchers found that when an algorithm controlled what information was shown to study participants on a subject they knew nothing about, they tended to narrow their focus and only explore a limited subset of the information that was available to them.   As a result, these participants were often wrong when tested on the information they were supposed to learn – but were still overconfident in their incorrect answers.   The ...

Most older drivers aren’t thinking about the road ahead, poll suggests

2025-11-25
Note: December 1-5 is Older Driver Safety Awareness Week   When today’s older adults learned to drive, they might have heard the Beatles’ “Drive My Car” or Bruce Springsteen’s “Born to Run” on their car radio’s Top 40 station. Now, 84% of people age 65 and older drive at least once a week, and 62% drive most days, according to a new University of Michigan national poll. But less than half of these older drivers have made a plan for a time down the road, when changes ...

Earthquakes shake up Yellowstone’s subterranean ecosystems

2025-11-25
Up to 30% of life, by weight, is underground. Seismic activity may renew the energy supply for subterranean ecosystems. Eric Boyd and colleagues chronicled the ecological changes in subsurface microbial communities that took place after a swarm of small earthquakes rattled the Yellowstone Plateau Volcanic Field in 2021. Subsurface microbial communities are powered by chemical energy gleaned from the interactions between rocks and water. Earthquakes can expose new rocks, release trapped fluids, and alter the flow path of water, together kicking off new reactions and changing the chemical “menu” for subsurface ...

Pusan National University study reveals a shared responsibility of both humans and AI in AI-caused harm

2025-11-25
Artificial intelligence (AI) is becoming an integral part of our everyday lives and with that emerges a pressing question: Who should be held responsible, when AI goes wrong? AI lacks consciousness and free-will, which makes it difficult to blame the system for the mistakes. AI systems operate through complex, opaque processes in a semi-autonomous manner. Hence, even though the systems are developed and used by human stakeholders, it is impossible for them to predict the harm. The traditional ethical frameworks thus fail to explain who is responsible for these harms, leading to the so-called responsibility gap in AI ethics. A recent study by Dr. Hyungrae Noh, an Assistant ...

Nagoya Institute of Technology researchers propose novel BaTiO3-based catalyst for oxidative coupling of methane

2025-11-25
Perovskites—a class of compounds with a unique ABX3 structure and high temperature stability—are promising materials for energy conversion. In recent years, they have been utilized in photovoltaic systems. They exhibit excellent performance in solid oxide fuel cells and organic reactions such as oxidative coupling of methane (OCM) for the production of ethane and ethylene. Notably, BaTiO3 is a promising perovskite with applications in fields including ferroelectricity, piezoelectricity, and semiconductivity. It possesses a flexible lattice and rich defect chemistry, making it suitable for structural modifications via doping for enhanced functional performance. Furthermore, ...

AI detects first imaging biomarker of chronic stress

2025-11-25
CHICAGO – Using a deep learning AI model, researchers identified the first-of-its-kind biomarker of chronic stress detectable through routine imaging, according to research being presented next week at the annual meeting of the Radiological Society of North America (RSNA). Chronic stress can affect both physical and psychological well-being, causing a variety of problems including anxiety, insomnia, muscle pain, high blood pressure and a weakened immune system, according to the American Psychological Association. Research shows that chronic stress can contribute to the development of major illnesses, such as heart ...

Shape of your behind may signal diabetes

2025-11-25
CHICAGO – The shape of the gluteus maximus muscle in the buttocks changes in different ways with aging, lifestyle, frailty, osteoporosis and type 2 diabetes, and these changes differ between women and men, according to new research being presented next week at the annual meeting of the Radiological Society of North America (RSNA). The researchers used MRI 3D mapping, a technique that processes a series of MRI images to create a detailed 3D anatomical model, allowing for improved visualization. The 3D mapping revealed distinct, sex-specific patterns in the gluteus maximus that were associated with type 2 diabetes, suggesting that the shape—not the size—of the muscle ...

Scientists identify five ages of the human brain over a lifetime

2025-11-25
Four major turning points around age nine, 32, 66 and 83 create five broad eras of neural wiring over the average human lifespan.    Typical adolescent brain development lasts until our early thirties on average, when the adult era of neural wiring finally emerges.  Neuroscientists at the University of Cambridge have identified five “major epochs” of brain structure over the course of a human life, as our brains rewire to support different ways of thinking while we grow, mature, ...

Scientists warn mountain climate change is accelerating faster than predicted, putting billions of people at risk

2025-11-25
Temperature, rainfall, and snowfall patterns are shifting at an accelerated rate in mountain regions  Over one billion people worldwide depend on mountain snow and glaciers for water, including the populations of China and India  As temperatures rise, more snow is changing to rain, decreasing mountain snowfall  Mountains worldwide are experiencing climate change more intensely than lowland areas, with potentially devastating consequences for billions of people who live in and/or depend on these regions, according to a major global review.  The international study, published in Nature Reviews Earth & Environment, examines ...

The ocean is undergoing unprecedented, deep-reaching compound change

2025-11-25
Earth's ocean, the planet's life-support system, is experiencing rapid and widespread transformations that extend far below its surface. A promising international study published in Nature Climate Change reveals that vast regions of the global ocean are experiencing compound state change, with simultaneously warming, becoming saltier or fresher, losing oxygen, and acidifying—clear indicators of climate change pushing marine environments into uncharted territory. Led by researchers from the Institute of Atmospheric Physics (Chinese Academy of Sciences), Mercator Ocean International (MOI, France), and the Laboratoire ...

Autistic adults have an increased risk of suicidal behaviours, irrespective of trauma

2025-11-25
Autistic people are more likely to report suicide-related behaviours and psychological distress irrespective of previous traumatic experiences, according to new research from the University of Cambridge. Additionally, the study shows for the first time that higher levels of trauma are associated with an increased likelihood of reporting suicide-related behaviours and psychological distress in autistic people — as is the case in the general population. Given that autistic people are recognised as a priority group for suicide prevention in the UK, these findings have important implications for national suicide prevention strategies. ...

Hospital bug jumps from lungs to gut, raising sepsis risk

2025-11-25
A hospital-acquired bacterium that causes serious infections can move from the lungs to the gut inside the same patient, raising the risk of life-threatening sepsis, new research reveals. Published today (25 November) in Nature Communications, researchers at the Wellcome Sanger Institute analysed DNA data taken from hospital patients to understand movement of the bacterium, Pseudomonas aeruginosa (P. aeruginosa) within individuals. The research sheds light on how lung infections can result in the spread of a major disease-causing bacterium between multiple parts of the body, increasing the risk of sepsis in vulnerable patients. The insights from the study may inform ...

Novel discovery reveals how brain protein OTULIN controls tau expression and could transform Alzheimer's treatment

2025-11-25
ALBUQUERQUE, NM and MEMPHIS, TN – November 25, 2025 – Scientists have uncovered a surprising mechanism by which a brain enzyme called OTULIN controls the expression of tau, the protein that forms toxic tangles in Alzheimer's disease. The findings, published today in Genomic Psychiatry, reveal that OTULIN functions not only as expected in protein degradation pathways but also plays a previously unknown role as a master regulator of gene expression and RNA metabolism. The research team, led by Dr. Kiran Bhaskar at the University of New Mexico Health Sciences Center and Dr. Francesca-Fang Liao at the University of Tennessee Health ...

How social risk and “happiness inequality” shape well-being across nations

2025-11-25
In recent years, governments worldwide have expressed concern over rising inequality, eroding social cohesion, and declining trust in institutions. This study, led by Professor Ken’ichi Ikeda from the Faculty of Social Studies, Doshisha University, Japan, in collaboration with Associate Professor Naoki Akaeda from the Faculty of Sociology, Kansai University, Japan, contributes to that debate. They demonstrate that subjective well-being (SWB) is deeply tied to both a country’s overall risk climate and the configuration of happiness inequality, where society resembles a “weak pyramid” or an “inverted pyramid.” Understanding ...

Uncovering hidden losses in solar cells: A new analysis method reveals the nature of defects

2025-11-25
A joint research team led by Dr. Hee-Eun Song of the Photovoltaics Research Department at the Korea Institute of Energy Research (President Yi Chang-Keun, hereafter “KIER”) and Prof. Ka-Hyun Kim of the Department of Physics at Chungbuk National University (President Koh Chang-Seup, hereafter “CBNU”) has successfully identified, for the first time, the specific types of defects responsible for efficiency loss in silicon heterojunction (SHJ) solar cells. The findings are expected to significantly contribute to improving solar cell efficiency when combined with defect-suppression (passivation) techniques. * Silicon Heterojunction ...

Unveiling an anomalous electronic state opens a pathway to room-temperature superconductivity

2025-11-25
Superconductive materials can conduct electricity with no resistance, but typically only at very low temperatures. Realizing superconductivity at room temperature could enable advanced, energy-efficient electronics and other technologies. Now, an international research team is one step closer to such an achievement. The researchers made the first observation of a special electronic state known as a “nodal metal,” which provides more insight into electronic behavior at different temperatures, in a multilayer system comprising copper and oxygen. The team, which includes researchers based in Japan, ...
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