CHEST releases guideline on biologic management in severe asthma
2026-01-13
Glenview, Illinois –The American College of Chest Physicians® (CHEST) recently released a new clinical guideline on biologic management in severe asthma. Published in the journal CHEST®, the guideline contains seven evidence-based recommendations to provide a framework for pulmonologists, allergists, and immunologists to implement in their own practice.
Severe asthma affects 5% to 10% of patients with asthma, which is defined as patients who require high-dose ...
Scientists create a system for tracking underwater blackouts
2026-01-13
(Santa Barbara, Calif.) — Clouds, smoke and fog may darken the skies, but sediment, algae blooms and organic matter can turn day into night on the seafloor. That’s why an international team of scientists have created the first framework to identify and compare these marine blackouts. The study, published in Communications Earth & Environment, introduces the concept of a marine darkwave: a short-term but intense episode of underwater darkness that can severely impact kelp forests, seagrass beds and other light-dependent ...
Fruit fly pigmentation guides discovery of genes that control brain dopamine and sleep
2026-01-13
Dopamine in the brain influences movement, learning, motivation and sleep. In humans, problems with dopamine are linked to conditions like Parkinson’s disease, depression and sleep disorders. While scientists know a great deal about how dopamine works in the brain, they know less about how the body controls dopamine levels. Understanding this could help treat diseases where dopamine is disrupted.
In a new study published in iScience, researchers at Baylor College of Medicine and the Jan and Dan Duncan Neurological Institute at Texas Children’s Hospital (Duncan NRI) worked with the laboratory fruit fly to find new genes involved in regulating dopamine ...
World's largest physics conference to be held in Denver and online this March
2026-01-13
More than 14,000 physicists from around the world will convene to present groundbreaking research at the American Physical Society’s Global Physics Summit. The conference will be held in person in Denver and online everywhere March 15-20.
Scientific program
The scientific program includes more than 12,000 individual presentations on new research in astrophysics, particle physics, quantum information science, biological physics, energy research, and more. For more information, search the scientific program. All times are in Mountain time.
Hybrid format
The Global Physics Summit will have both in-person and online experiences. The in-person ...
New mega-analysis reveals why memory declines with age
2026-01-13
A landmark international study that pooled brain scans and memory tests from thousands of adults has shed new light on how structural brain changes are tied to memory decline as people age.
The findings — based on more than 10,000 MRI scans and over 13,000 memory assessments from 3,700 cognitively healthy adults across 13 studies — show that the connection between shrinking brain tissue and declining memory is nonlinear, stronger in older adults, and not solely driven by known Alzheimer’s-associated genes like ...
Understanding ammonia energy’s tradeoffs around the world
2026-01-13
Many people are optimistic about ammonia’s potential as an energy source and carrier of hydrogen, and though large-scale adoption would require major changes to the way it is currently manufactured, ammonia does have a number of advantages. For one thing, ammonia is energy-dense and carbon-free. It is also already produced at scale and shipped around the world, primarily for use in fertilizer.
Though current manufacturing processes give ammonia an enormous carbon footprint, cleaner ways to make ammonia do exist. A better understanding of how to guide the ammonia fuel industry’s continued development ...
UTHealth Houston researchers map gene disruptions in sporadic early onset Alzheimer’s disease across key brain regions
2026-01-13
A new study led by researchers at UTHealth Houston investigated both gene expression and regulation at single cell levels to reveal disruptions in gene function in three brain regions of patients with sporadic early onset Alzheimer’s disease.
The findings were published in Science Advances.
Only about 5% to 10% of patients with Alzheimer’s disease are younger than 65. Of those patients, 10% have mutations in the APP, PSEN1, and PSEN2 genes, which are associated with Alzheimer’s disease. The other 90% of these cases are classified as sporadic early onset Alzheimer’s, a rare and aggressive form of the ...
Minimum wage increases are linked to safer pregnancies
2026-01-13
Increases to the minimum wage may do more than bolster household income, reduce inequality and enhance worker well-being: They may also help make pregnancies safer, according to new research from Rutgers University.
A study published online ahead of the Fe in the American Journal of Preventive Medicine finds that state-level increases in the minimum wage are associated with lower rates of hypertensive disorders of pregnancy, a leading cause of maternal mortality in the United States.
The study, led by Slawa Rokicki, an assistant professor at the Rutgers School of Public Health, ...
Left in the cold: Study finds most renters shut out of energy-saving upgrades
2026-01-13
As winter heating costs rise, new research from Binghamton University, State University of New York reveals a cold truth. Renters – who make up approximately ⅓ of the U.S. population – are missing out on energy efficiency improvements that could lower their bills, make their apartments more comfortable and improve their health.
This study, “Still muddling through: Local sustainability leaders and energy efficiency in rental units,” was published in Energy Research & Social Science. ...
This crystal sings back: Illinois collaboration sheds light on magnetochiral instability
2026-01-13
Researchers from The Grainger College of Engineering at the University of Illinois Urbana-Champaign have reported the first observation of a dynamic magnetochiral instability in a solid-state material. Their findings, published in Nature Physics, bridge ideas from nuclear and high-energy physics with materials science and condensed matter physics to explain how interplay between symmetry and magnetism can amplify electromagnetic waves.
A material’s behavior is heavily influenced ...
Organisms in the Atacama Desert soil are remarkably diverse
2026-01-13
A new study shows that resilient and remarkably diverse populations of organisms can persist in the soil despite harsh and extremely dry conditions. An international team led by researchers from the University of Cologne, has examined tiny nematodes in the Chilean Atacama Desert. Along with the polar regions, the Atacama Desert is considered one among these most arid regions in the world. Lack of rainfall, high salt content in the soil, and extreme temperature fluctuations make it one of the most hostile places on earth. The interdisciplinary team with researchers from the fields of zoology, ecology and botany demonstrated the strategies used by different nematodes ...
Children’s Hospital Colorado research outlines first pediatric classifications for suicide risk in adolescents and kids
2026-01-13
AURORA, Colo. (January 13, 2025) – Today, pediatric experts from Children’s Hospital Colorado (Children’s Colorado) announced published research in the Journal of the American Academy of Child and Adolescent Psychiatry that identifies five classifications of youth who have died by suicide. Using 10 years of national suicide data, Joel Stoddard, MD, MAS, child and adolescent psychiatrist at Children’s Colorado, and his team found that nearly half of youth who died by suicide did not have clinical contact or a known ...
No thyme wasted: Harnessing the medicinal benefits of thyme extract With small doses
2026-01-13
WASHINGTON, Jan. 13, 2026 — With a myriad of health effects, thyme extract may seem like a magic medicinal ingredient. Its biologically active compounds — thymol, carvacrol, rosmarinic acid, and caffeic acid — provide anti-inflammatory, antimicrobial, antioxidant, and immune benefits.
But thyme extract also has downsides. It vaporizes quickly (a waste of thyme!), making it challenging to use, and too much of it can be irritating, causing rashes and digestive issues.
A solution to both problems is to encapsulate nanodroplets of thyme extract within another fluid, ...
Fat surrounding the colon interacts with the immune system
2026-01-13
Abdominal fat is not a uniform tissue. A new study from Karolinska Institutet, Steno Diabetes Center Copenhagen, and Helmholtz Munich reveals that fat located close to the large intestine contains an unusually high number of inflammatory fat cells and immune cells. The findings suggest that this tissue is specially adapted to communicate with the immune system in the gut region. The study is published in the journal Cell Metabolism.
In the study, researchers mapped five different abdominal fat depots in individuals with severe obesity. The results show clear differences between these depots. Most striking is the so-called epiploic fat tissue along the ...
Genetic predisposition to excess body weight and survival in women diagnosed with breast cancer
2026-01-13
About The Study: In this cohort of nonmetastatic breast cancer survivors, women who were genetically predisposed to having a higher body mass index were at increased risk of all-cause mortality. Targeted lifestyle recommendations to mitigate their genetic predisposition should be considered to lower this risk.
Corresponding Author: To contact the corresponding author, Clara Bodelon, PhD, MS, email clara.bodelon@cancer.org.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamanetworkopen.2025.53687)
Editor’s Note: Please ...
New mechanism links Epstein-Barr virus to MS
2026-01-13
The immune system’s reaction to the common Epstein-Barr virus can ultimately damage the brain and contribute to multiple sclerosis (MS). This is shown by new research from Karolinska Institutet, published in Cell. The study provides new insight into the long-suspected link between Epstein-Barr virus (EBV) and MS.
Multiple sclerosis is a chronic inflammatory disease in which the immune system attacks the central nervous system and causes nerve damage. It has long been known that everyone who develops MS has had an infection with the Epstein-Barr virus (EBV) – a common virus that often infects young people, sometimes causing glandular fever but ...
Genetic risk factor and viral infection jointly contribute to MS
2026-01-13
One of the leading triggers for multiple sclerosis (MS) is an infection with the Epstein-Barr virus. However, certain gene variants also play an important role. Researchers at the University of Zurich have now shown that it is the molecular interaction between environmental and genetic risk factors that ultimately triggers the disease.
Recent findings suggest that the Epstein-Barr virus (EBV) is involved in both causing multiple sclerosis (MS) and shaping its progression. Everyone who has MS has previously ...
When a virus releases the immune brake: New evidence on the onset of multiple sclerosis
2026-01-13
Autoimmune diseases such as multiple sclerosis arise when the immune system turns against the body itself. Yet for most of them, it remains unclear why this process begins. Researchers have now identified how the Epstein-Barr virus can, under specific conditions, initiate early multiple sclerosis-like damage in the brain. This offers a new perspective on how rare immune events may shape disease risk.
There is mounting evidence that the Epstein-Barr virus may play a part in causing autoimmune diseases like multiple sclerosis. But one puzzle remains: almost everyone gets this virus early in life, yet only ...
Wyss Institute-led collaboration awarded by ARPA-H PRINT program to engineer off-the-shelf, universal, transplant-ready graft for liver failure
2026-01-13
(BOSTON) — The majority of human illnesses is caused by damage of a single organ like the liver whose failure accounts for 2M deaths worldwide every year. Orthotopic transplants are the only curative therapy available, but the severe shortage of donor organs, which are reserved for the most severe cases, leaves millions of patients without an accessible solution.
The liver is the central hub in our body for filtering blood, metabolizing nutrients and toxins, producing essential proteins and bile, storing vitamins and glucose, and a multitude of other processes. Accordingly, an excessive loss of liver function through various diseases poses ...
Research on the behavioral mechanisms of rural distributed photovoltaic development: A view of prosumer perspective
2026-01-13
As global energy transitions accelerate, distributed PV systems have become a cornerstone of rural energy transformation in China, shifting rural households from passive energy consumers to active prosumers. However, low household electricity demand, limited grid capacity, and complex stakeholder interactions hinder widespread adoption.
To address these challenges, researchers Wenbing Zhou and Songlin Tang from the School of Economics at Shandong Technology and Business University developed a multi-agent dynamic game model. The model incorporates four core stakeholders: village organizations, PV enterprises, grid companies, and rural households, analyzing their ...
More surgical patients are on opioid use disorder medications — hospitals must modernize pain care
2026-01-13
More Surgical Patients Are on Opioid Use Disorder Medications — Hospitals Must Modernize Pain Care
CHICAGO – As more Americans receive treatment for opioid use disorder, that progress is increasingly showing up in the operating room, creating an urgent need to modernize how pain is managed during and after major surgery, according to a study in the February 2026 issue of Anesthesiology, the peer-reviewed medical journal of the American Society of Anesthesiologists (ASA). The study documents a steady rise in surgical patients using medications for opioid use disorder (MOUD), highlighting a gap between current surgical pain practices and the needs of today’s patients.
"From ...
New study reveals strategic logic behind global patent litigation venue selection
2026-01-13
A new study published in the Strategic Management Journal sheds light on how multinational firms make strategic decisions about where to pursue patent litigation in an increasingly interconnected and politically complex global environment. Rather than treating patent disputes as isolated, country-by-country legal actions, the research shows that firms approach litigation as part of a coordinated global strategy.
Drawing on patent litigation data from leading technology firms across 50 countries over ...
An abnormally slow heart rate is associated with xylazine-fentanyl overdose; primarily seen in northeastern United States
2026-01-13
Researchers have identified bradycardia—an abnormally low heart rate–as a symptom of xylazine-opioid overdose. This breakthrough finding from the Icahn School of Medicine at Mount Sinai may help emergency medicine physicians detect whether patients have been exposed to xylazine, a drug that is increasingly found as an additive to the illicit fentanyl supply, particularly in the Northeast.
Accurate detection of xylazine overdose could help physicians take the correct steps to save lives ...
The path to solar weather forecasts
2026-01-13
At times the sun ejects energetic material into space which can have consequences for space-based and even ground-based electronic technology. Researchers aim to understand this phenomenon and find ways to forecast it, including how ejected material evolves as it travels through the solar system. For the first time, researchers, including those from the University of Tokyo, made high-quality measurements of an evolving cloud of solar ejecta by using multiple space-based instruments which were not designed to do so, and observed the way the ...
Inflammation and mitochondrial dysfunction in cirrhotic cardiomyopathy: therapeutic implications
2026-01-13
Background and Aims
Cirrhotic cardiomyopathy (CCM) is a significant complication of cirrhosis, but its progression and underlying mechanisms remain incompletely understood. This study aimed to investigate dynamic changes in cardiac function, pathology, inflammation, and mitochondrial damage in a mouse model of CCM, and to compare echocardiographic characteristics in patients with cirrhosis.
Methods
Bile duct ligation was performed in male C57BL/6J mice to induce cirrhosis. Longitudinal analyses were conducted over eight weeks. Cardiac function was assessed using serum biomarkers, echocardiography, and electrocardiography. Pathology was examined with hematoxylin and eosin, ...
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