22 JANUARY 2026 SINGAPORE – Scientists from A*STAR Institute of Molecular and Cell Biology (A*STAR IMCB) have identified why certain lung cancer cells become highly resistant to treatment after developing mutations in a key gene called EGFR (epidermal growth factor receptor). In a study published in Science Advances, the researchers revealed a previously unknown survival mechanism and demonstrated that disrupting it can shrink tumours in laboratory models. Lung cancer is the leading cause of cancer deaths globally. Many cases are driven by mutations in the EGFR gene, which causes cells to grow and divide uncontrollably. In Southeast Asia, these mutations are found in ...

How can bacteria squeeze through spaces narrower than a human hair is thick? A research team in Japan led by Dr. Daisuke Nakane and Dr. Tetsuo Kan at the University of Electro-Communications, Dr. Hirofumi Wada at Ritsumeikan University, and Dr. Yoshitomo Kikuchi at National Institute of Advanced Industrial Science and Technology have revealed the answer: they drill their way through. The study, published in Nature Communications, shows that certain symbiotic bacteria wrap their rotating flagella—the helical tails used for swimming—around their cell bodies to form a “screw thread.” This configuration lets them propel forward through one-micrometer-wide passages, such ...

LOGAN, Utah, USA — A recent critique from a team led by Utah State University ecologist Dan MacNulty and published in Forest Ecology and Management has prompted a formal correction to a high-profile study on aspen recovery while raising broader questions about how scientific conclusions are drawn and defended in complex ecological systems. The original study, published last year by Luke Painter and colleagues, concluded that restoration of large carnivores — including the reintroduction of wolves in the mid-1990s — triggered a strong, ecologically significant trophic cascade that fostered widespread recovery of aspen trees in northern Yellowstone. Central to their evidence ...

Gaps in the nation’s stroke transfer system are drastically reducing survivors’ chances of receiving critical treatment and increasing the likelihood that they will leave the hospital with a disability, a new study suggests. Around one-third of ischemic stroke survivors are eligible for endovascular thrombectomy, an effective intervention that changed the landscape of stroke treatment more than a decade ago. More than 40% of people who receive endovascular therapy are initially seen at hospitals that don’t offer the treatment. These patients require transfer to more advanced facilities capable of delivering thrombectomy.  New findings published in The Lancet ...

Gaps in the U.S. stroke transfer system are drastically reducing survivors’ chances of receiving critical treatment and increasing the likelihood that they will leave the hospital with a disability, according to a new study published in The Lancet Neurology. Around one-third of ischemic stroke patients are eligible for endovascular thrombectomy, an effective intervention that changed the landscape of stroke treatment more than a decade ago. More than 40% of people who receive endovascular therapy initially arrive at hospitals that don’t offer the treatment. These patients require transfer to more advanced facilities capable of delivering ...

The long term use of proton pump inhibitors (PPIs), a class of drugs widely used to treat acid reflux and ulcers, may not be linked to any increased risk of developing gastric (stomach) cancer, finds a study of Nordic health data published by The BMJ today. This finding should offer relief for patients needing long term proton pump inhibitor therapy and is valuable for clinical decision making in healthcare settings, say the researchers. A fear that proton pump inhibitors could lead to stomach cancer has been ongoing since the 1980s. Recent research has linked their use to around a twofold increased risk, but ...

Offering non-monetary incentives such as free access to outpatient consultations to frequent blood donors is linked to an increase in donations without compromising blood safety, finds a study from China published by The BMJ today. The researchers say their findings could encourage policymakers in other countries to design their own incentive models to address blood shortages. Many countries, particularly developing ones, struggle to sustain an adequate blood supply due to challenges of retaining blood donors under the “gift model” - a ...

Natural ovulation before frozen embryo transfer is as effective as hormone treatment for achieving a healthy baby by vitro fertilisation (IVF), finds a clinical trial from China published by The BMJ today. Natural ovulation is also linked to a lower risk of several complications for the mother, such as pre-eclampsia (abnormally high blood pressure), the results show. Globally, the use of frozen embryo transfer after IVF has increased substantially and accounts for more than 60% of all embryo transfers. Doctors prepare the womb lining (endometrium) for frozen ...

A major UK clinical trial has shown that adding the corticosteroid dexamethasone to standard antiviral treatment for encephalitis (brain inflammation), caused by herpes simplex virus (HSV) does not improve long-term outcomes overall, although early use may lead to better recovery, and the treatment is safe for patients in whom encephalitis is suspected. The DexEnceph study, led by researchers at The Pandemic Institute, the University of Liverpool, and Walton Centre NHS Foundation Trust in partnership with Encephalitis International and research teams around the country, provides the most definitive evidence so far on whether corticosteroids should be used ...

Severe vitamin D deficiency is associated with a higher rate of hospitalisation for respiratory tract infections such as bronchitis and pneumonia, according to a new study led by the University of Surrey. Scientists found that those with a severe deficiency (below 15 nnmol/L) were 33 per cent more likely to be admitted to hospital for treatment than those with sufficient levels of vitamin D (at least 75 nmol/L).  In the largest study of its kind, analysing NHS data from the UK Biobank, researchers from Surrey, in collaboration with the University of Reading ...

There has been a lasting and disproportionate impact of the Covid-19 pandemic on diagnosis rates for conditions including depression, asthma and osteoporosis. Depression is the most severely impacted, with almost a third fewer diagnoses than expected compared with pre-pandemic trends. The King’s College London study is the first to evaluate whether diagnosis rates have recovered after emerging from the pandemic. Published today in the British Medical Journal (BMJ), it uses anonymised data from over 29 million people in England. The pandemic had an unprecedented impact on healthcare systems around the world, leading to abrupt decreases ...

A 66 million-year-old mystery behind how our planet transformed from a tropical greenhouse to the ice-capped world of today has been unravelled by scientists. Their new study has revealed that Earth’s massive drop in temperature after the dinosaurs went extinct could have been caused by a large decrease in calcium levels in the ocean. An international team of experts led by the University of Southampton discovered that concentrations of calcium in the sea dropped by more than half across the last 66 million years. The ...

Key points: Red light therapy is an emerging therapy which shines near-infrared light into the brain through the skull, aiming to reduce inflammation. A preliminary study with 26 football players suggests that red light therapy could prevent brain inflammation caused by repetitive impacts. IMPACT: If larger studies confirm the results, red light therapy could help protect people who experience frequent head impacts, like soldiers and athletes, from long-term health consequences. Punch-drunk syndrome, boxer’s madness, chronic traumatic encephalopathy (CTE). The name has changed over the years, but the cause is clear: repeated impacts can affect long-term brain health, with symptoms ...

A multi-institutional study led by the University of California, Davis, finds that living in urban areas with a higher percentage of visible trees is associated with a 4% decrease in cardiovascular disease. By comparison, living in urban areas with a higher percentage of grass was associated with a 6% increase in cardiovascular disease. Likewise, a higher rate of other types of green space, like bushes or shrubs, was associated with a 3% increase in cardiovascular disease. The new research was published in Environmental Epidemiology. “Our ...

ATLANTA (Jan. 20, 2026) – UL Research Institutes’ Chemical Insights scientist Katie Paul Friedman, Ph.D. received the prestigious 2026 Achievement Award from the Society of Toxicology (SOT). SOT recognized Dr. Paul Friedman for her leadership in computational toxicology and her contributions to new approach methodologies (NAMs) that are transforming chemical safety assessment. Dr. Paul Friedman, Director of the Center for Informatics and Screening at Chemical Insights, was recognized for exemplifying scientific excellence and service through her innovative research, vision on addressing regulatory needs with NAMs, and dedication ...

A research team, led by Professor of Chemistry at NYU Abu Dhabi Panče Naumov, in collaboration with a research team led by Professor Hongyu Zhang at Jilin University, China, has discovered a new type of organic crystal that can repair itself after being damaged at extremely low temperatures. This breakthrough could pave the way for the next generation of durable, lightweight materials designed to perform in some of the harshest environments on Earth and beyond. The material, which is one of the newly researched materials known as smart molecular crystals whose discovery was pioneered by Naumov’s group, can restore its structure even ...

In a major scientific breakthrough, researchers from Monash University and the Lions Eye Institute have discovered a tissue protein that acts as a central ‘traffic controller’ for immune cells and can be hijacked by a virus to weaken immune responses.  Published today in Nature, the study discovered a key mechanism that controls how immune cells coordinate their responses, and how a common virus can sabotage it. The research reveals that a molecule called CD44 centrally controls the network of support cells that guide immune system function. Within this network of support cells, stromal cells help immune cells move efficiently and exchange the information needed ...

The tropical oceans that once served as oxygen-rich havens for Earth's earliest complex life have become the planet's largest marine dead zones. The dramatic reversal occurred hundreds of millions of years ago and researchers are now beginning to better understand its timing. A new study led by former Syracuse University doctoral student Ruliang He and co-authored by his advisor, Earth and environmental sciences Professor Zunli Lu, reveals that Earth's ancient tropical oceans were ...

A six-year analysis of marine microbes in coastal California waters has overturned long-held assumptions about how the ocean's smallest organisms interact.  Researchers at UC San Diego’s Scripps Institution of Oceanography found that marine microbes interact in ways that benefit one another more often than they eat each other or compete. The team also found that periods of elevated ocean temperatures, usually times of stress for these microbes because of a dearth of nutrients, actually resulted in even more of these positive interactions. The study was published Jan. 21 in the ISME Journal: Multidisciplinary Journal of Microbial ...

New research into the impact of climate change on snow sports provides recommendations to increase the climate-resilience of the Olympic and Paralympic Winter Games. The University of Waterloo led the study, in collaboration with researchers at the University of Innsbruck and the University of Toronto, and it builds on their influential work to determine reliable locations for the Winter Games as global warming accelerates. The team analyzed the 93 potential host locations where the International Olympic Committee (IOC) indicated the necessary winter sports infrastructure was already in place. They found that if countries continue with current climate policies, only 52 would remain climate-reliable ...

Amid a surprisingly severe flu season and a Covid-19 resurgence, those highly contagious respiratory illnesses are drawing the largest share of media coverage and public attention. But it is also the season for another respiratory illness, respiratory syncytial virus or RSV, and RSV cases are “elevated in many areas of the country,” according to the Centers for Disease Control and Prevention (CDC). RSV data for the week of Jan. 5, 2026, show an increase both in emergency department visits and hospital admissions for children up to age four, according to CIDRAP, the Center for Infectious Disease Research & Policy, at the University of Minnesota. And the Pan American ...

A new, fast and easy test could revolutionize blood transfusions—giving blood centers and hospitals a reliable way to monitor the quality of red blood cells after they sit for weeks in storage.  The project is a collaboration between engineers and medical researchers at the University of Colorado Boulder and University of Colorado Anschutz. The team’s device hasn’t yet been approved for use. But the group hopes that it could one day help the United States better manage its precious blood supply. The entire test also fits on a single chip, said Xiaoyun ...

EMBARGOED FOR RELEASE UNTIL 4:00 P.M. ET, WEDNESDAY, JANUARY 21, 2026 MINNEAPOLIS — Having an ischemic stroke during pregnancy or three months after pregnancy is associated with an increased risk of cardiovascular events like heart attack or second stroke, heart disease and depression later in life. The new study is published on January 21, 2026, in Neurology®, the medical journal of the American Academy of Neurology. Ischemic stroke is the most common type of stroke. It occurs when a clot or blockage reduces blood flow to the brain, depriving it of oxygen and nutrients. The study also found that female participants who had ...

Atmospheric scientist Amanda Staudt will join the American Meteorological Society (AMS), the professional society for weather, water, and climate sciences and services, as its new executive director in March 2026.  Staudt, who previously served as senior director of Climate Crossroads at the National Academies of Sciences, Engineering, and Medicine, has decades of experience helping translate science into informed decision-making in collaboration with major scientific organizations. As executive director, Staudt ...

While many people binge-watch their favorite shows, binge-watching addiction is associated with loneliness, according to a study published January 21, 2026 in the open-access journal PLOS One by Xiaofan Yue and Xin Cui from Huangshan University in China. COVID-19 drove many people indoors and onto the couch, driving concerns about mental health, especially as people were also isolated and distressed. Now, while many people have resumed daily activities, some people binge-watch to the point of addiction—experiencing obsession, ...