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Crosswalk confusion: MA drivers flummoxed by pedestrian hybrid beacons, find UMass Amherst researchers

2025-10-07
Crosswalk Confusion: MA Drivers Flummoxed by Pedestrian Hybrid Beacons, find UMass Amherst Researchers   Among other findings, nearly a quarter of drivers run through the red light.   AMHERST, Mass. — Stopping early, failing to stop or rolling through—new research from University of Massachusetts Amherst reveals that more awareness of the rules of the road around this crosswalk design is necessary. Published in Transportation Research Record, the study looked at how Massachusetts drivers behave at pedestrian hybrid beacons, a type of crosswalk device increasingly found at mid-block crosswalks where there ...

Study shows heart disease mortality disproportionately burdens low-income communities in California

2025-10-07
Heart disease mortality is on the rise in California, accelerated by socioeconomic disparities that disproportionately impact marginalized communities, according to a study being presented at ACC Quality Summit 2025 taking place October 14 – 16 in Denver. It’s crucial to align prevention with equity and implement data-driven, community-focused interventions that address this heightened cardiovascular burden in low-income communities, the authors said. “By using state and federal data, I wanted to identify which risk factors such as hypertension, diabetes, obesity, and smoking remain inadequately addressed ...

Intracardiac echocardiography recognized as ‘transformative’ imaging modality in new SCAI position statement

2025-10-07
WASHINGTON—The Society for Cardiovascular Angiography & Interventions (SCAI) has published a comprehensive roadmap that details the use of intracardiac echocardiography (ICE) to guide structural heart disease (SHD) interventions for clinicians. ICE represents a significant departure from the traditional reliance on transesophageal echocardiography (TEE) by providing clinicians with real-time, high-resolution imaging from inside the heart without the need for general anesthesia.   Published in JSCAI, “SCAI Position Statement on Intracardiac Echocardiography to Guide Structural Heart Disease Interventions” ...

Study finds ‘man’s best friend’ slows cellular aging in female veterans

2025-10-07
New research finds that “man’s best friend” may help slow biological aging in women. This groundbreaking study, focused on female veterans in the United States, is among the first to examine the impact of working with service dogs on this often-overlooked population. By measuring biological indicators of stress, the researchers have uncovered a key insight: the way stress is felt emotionally doesn’t always reflect how it affects the body at a cellular level. While women have served in the U.S. military for generations, ...

To get representative health data, researchers hand out fitbits

2025-10-07
A study finds that a representative sample of people given wearable data collection devices provides more equitable and accurate health data than larger convenience samples of people who already own wearable devices. Leveraging the smartwatches and other data-logging wearables that people already have is a tempting way to gather data, but such groups overrepresent the wealthy, urban, White, and fit people who tend to buy these products. Ritika Chaturvedi and colleagues recruited 1,038 participants for American Life in Realtime (ALiR), a longitudinal health study that provided Fitbits ...

Hiring in high-growth firms: new study explores the timing of organizational changes

2025-10-07
High-growth firms (HGFs) refer to businesses that achieve rapid growth in terms of employees or revenue. Based on the established definition, HGFs are businesses with at least 10 employees and annual growth rates of 20% or more, observed over a period of three years. This three-year span is considered the high-growth (HG) period of the company. Even though this growth is often short-lived and difficult to sustain, it plays a significant role in driving economic dynamism. Hence, entrepreneurship-related research often focuses on the growth ...

Boosting work engagement through a simple smartphone diary

2025-10-07
Work engagement is a positive and persistent state of mind related to one’s work. It is characterized by high energy and mental resilience (vigor), enthusiasm and involvement (dedication), and complete concentration in the task at hand (absorption). Engaged workers are not merely more productive; they are more likely to be proactive, creative, and less susceptible to burnout. Most importantly, work engagement has been consistently linked to many health benefits and overall well-being. Despite its relevance for both organizations and workers alike, there aren’t many scientifically proven ...

Climate change may create ‘ecological trap’ for species who can’t adapt

2025-10-07
CLEVELAND—Even as autumn days grow shorter, a warming climate means Ohio winters aren't as cold as they were just a few decades ago, according to National Oceanic and Atmospheric Administration data. This increasing mismatch between hours of daylight and temperature could spell trouble for animals that thrive by relying on seasonal cues to prepare their bodies for winter, according to new research from Case Western Reserve University. Scientists studying gray tree frogs—a species that survives freezing temperatures by storing “antifreeze” compounds in their bodies—have discovered that these amphibians naturally begin to prepare for winter by responding ...

Scientists create ChatGPT-like AI model for neuroscience to build one of the most detailed mouse brain maps to date

2025-10-07
Seattle, WASH.—October 7, 2025—In a powerful fusion of AI and neuroscience, researchers at the University of California, San Francisco (UCSF) and Allen Institute designed an AI model that has created one of the most detailed maps of the mouse brain to date, featuring 1,300 regions/subregions. This new map includes previously uncharted subregions of the brain, opening new avenues for neuroscience exploration. The findings were published today in Nature Communications. They offer an unprecedented level of detail and advance our understanding of the brain by allowing researchers ...

AI and omics unlock personalized drugs and RNA therapies for heart disease

2025-10-07
AI and omics unlock personalized drugs and RNA therapies for heart disease  AI, omics, and systems biology can now help scientists design targeted drugs for cardiovascular disease pathways once thought “untreatable.”   A new article published in Frontiers in Science says these tools could transform heart drug development and save lives—but that global, equitable health policy leadership is urgently needed.  Despite major advances in cardiovascular care, heart disease remains the world’s leading cause of death. This is partly because cardiovascular medicine still largely relies on broad-brush ...

2023 ocean heatwave ‘unprecedented but not unexpected’

2025-10-07
The June 2023 heatwave in northern European seas was “unprecedented but not unexpected”, new research shows. During the heatwave, temperatures in the shallow seas around the UK (including the North Sea and Celtic Sea) reached 2.9°C above the June average for 16 days. While unprecedented since observations began, the study warns that rapid climate change means there is now about a 10% chance of a marine heatwave of this scale occurring each year. The June 2023 marine heatwave significantly disrupted phytoplankton blooms. Although its full impact ...

Johns Hopkins researchers develop AI to predict risk of US car crashes

2025-10-07
In a significant step towards improving road safety, Johns Hopkins University researchers have developed an A.I.-based based tool that can identify the risk factors contributing to car crashes across the United States and to accurately predict future incidents.   The tool, called SafeTraffic Copilot, aims to provide experts with both crash analyses and crash predictions to reduce the rising number of fatalities and injuries that happen on U.S. roads each year.  The work, led by Johns Hopkins ...

New drug combination offers hope for men with advanced prostate cancer

2025-10-07
A new drug combination could significantly delay the progression of a life-threatening form of prostate cancer in men with specific genetic mutations, finds a major international trial led by UCL researchers. The Phase III AMPLITUDE trial, published in Nature Medicine, tested the addition of niraparib, a type of targeted cancer drug known as a PARP inhibitor1, to the standard treatment of abiraterone acetate and prednisone (AAP).2 The study focused on patients diagnosed with advanced prostate cancer where cells have spread to other parts of the body, who were starting their first ...

New discovery finds gene converts insulin-producing cells into blood-sugar boosters

2025-10-07
LOS ANGELES — Scientists at City of Hope®, one of the largest and most advanced cancer research and treatment organizations in the U.S., and a leading research center for diabetes and other life-threatening illnesses, have uncovered a gene called SMOC1 that plays a surprising role in the development of type 2 diabetes (T2D) by converting pancreatic cells that normally produce insulin into those that increase blood sugar.   The findings, published in Nature Communications, identify an important new therapeutic target for T2D and ...

Powerful and precise multi-color lasers now fit on a single chip

2025-10-07
A few years ago, researchers in Michal Lipson’s lab noticed something remarkable.  They were working on a project to improve LiDAR, a technology that uses lightwaves to measure distance. The lab was designing high-power chips that could produce brighter beams of light.  “As we sent more and more power through the chip, we noticed that it was creating what we call a frequency comb,” says Andres Gil-Molina, a former postdoctoral researcher in Lipson’s lab.  A frequency comb is a special type of light that contains many colors lined up next to each other in an orderly pattern, kind of like ...

Scientists agree chemicals can affect behavior, but industry workers more reluctant about safety testing

2025-10-07
Survey of 166 international experts highlights concerns about protecting human and wildlife health from environmental pollutants Less than a third of industry scientists support including behavioural tests in chemical safety assessments, compared to 80 per cent of academics and 91 per cent of government scientists Despite almost all scientists (97 per cent) agreeing that chemicals can affect wildlife behaviour, most testing is done by universities rather than chemical companies, leaving gaps ...

DNA nanospring measures cellular motor power

2025-10-07
Cells all require the transport of materials to maintain their function. In nerve cells, a tiny motor made of protein called KIF1A is responsible for that. Mutations in this protein can lead to neurological disorders, including difficulties in walking, intellectual impairment and nerve degradation. It’s known that mutations in KIF1A also result in a weakened motor performance, but this has been difficult to measure so far. Researchers including those from the University of Tokyo and the National Institute of Information and Communications Technology (NICT) in Japan have measured changes in the force of KIF1A using a nanospring, a tiny, coiled structure, ...

Elsevier Foundation and RIKEN launch “Envisioning Futures” report: paving the way for gender equity and women’s leadership in Japanese research

2025-10-07
A unique collaboration, the Elsevier Foundation and RIKEN, Japan’s premier research institute, have released “Envisioning Futures: Women’s Leadership and Gender Equity in Japanese Research,” a comprehensive report that shines a spotlight on the journeys, achievements and challenges faced by women research leaders in Japan. The report blends data-driven analysis with compelling personal narratives, offering a timely roadmap for institutional change and a call to action for the advancement of women in science and innovation. The report shows that despite Japan’s global reputation for technological ...

Researchers discover enlarged areas of the spinal cord in fish, previously found only in four-limbed vertebrates

2025-10-07
Four-limbed vertebrates, known as tetrapods, have two enlarged areas in their spinal cords. The two enlargements have a correlation with the forelimbs and hind limbs, respectively. These enlargements are thought to be caused by the complex muscular system and the rich sensory networks supplying nerves to the limbs. Meanwhile, it was long thought that fish had no enlarged areas in their spinal cords due to the absence of limbs. However, a recent study by scientists from Nagoya University in Japan has revealed that zebrafish, in fact, have enlarged areas in their spinal cords, although these areas are not visible ...

Bipolar disorder heterogeneity decoded: transforming global psychiatric treatment approaches

2025-10-07
HALIFAX, Nova Scotia, CANADA, 7 October 2025 -- In a compelling Genomic Press Interview published today in Genomic Psychiatry, Dr. Martin Alda illuminates how decoding psychiatric heterogeneity holds the key to revolutionizing mental health treatment worldwide. The interview reveals how this internationally acclaimed researcher transformed our global understanding of bipolar disorder by proving that what appears as one condition actually represents multiple genetically distinct disorders, fundamentally ...

Catching Alport syndrome through universal age-3 urine screening

2025-10-07
The most common first diagnosis of Alport syndrome in Japan is during the universal age-3 urine screening. In 60% of these children, the disease had already progressed far enough to qualify for treatment. Therefore, universal early-age urinalysis may be an apt means for both better prognoses and reduced costs of medical care. Alport syndrome is a genetic disease that affects about one in 5,000 people. Patients cannot produce a certain type of collagen which leads to kidney failure, and may also lead to hearing loss and ...

Instructions help you remember something better than emotions or a good night’s sleep

2025-10-07
A good night’s sleep has long been understood to help us consolidate new memories, but we don’t understand how. Associations with negative feelings like fear or stress can improve recall, but intentionally trying to remember can also be effective. But these two mechanisms are very different — one involuntary, one deliberate. Which influences memory most? To investigate, researchers asked participants to remember or forget words, some of which had negative emotional associations. They found that instructions improved recall ...

Solar energy is now the world’s cheapest source of power, a Surrey study finds

2025-10-07
Solar energy is now so cost-effective that, in the sunniest countries, it costs as little as £0.02 to produce one unit of power, making it cheaper than electricity generated from coal, gas or wind, according to a new study from the University of Surrey.  In a study published in Energy and Environment Materials, researchers from Surrey’s Advanced Technology Institute (ATI) argue that solar photovoltaic (PV) technology is now the key driver of the world’s transition to clean, renewable power.  Professor Ravi Silva, co-author of the study and Director of the ATI at the University ...

Scientists reverse Alzheimer’s in mice using nanoparticles

2025-10-07
A research team co-led by the Institute for Bioengineering of Catalonia (IBEC) and West China Hospital Sichuan University (WCHSU), working with partners in the UK, has demonstrated a nanotechnology strategy that reverses Alzheimer’s disease in mice. Unlike traditional nanomedicine, which relies on nanoparticles as carriers for therapeutic molecules, this approach employs nanoparticles that are bioactive in their own right: “supramolecular drugs.” Instead of targeting neurons directly, the therapy restores the proper function of the blood-brain barrier (BBB), the vascular gatekeeper ...

‘Good’ gut bacteria boosts placenta for healthier pregnancy

2025-10-07
Research led by the University of Cambridge has found the first clear evidence that the ‘good’ gut bacteria Bifidobacterium breve in pregnant mothers regulates the placenta’s production of hormones critical for a healthy pregnancy. In a study in mice, the researchers compared the placentas of mice with no gut bacteria to those of mice with Bifidobacterium breve in their gut during pregnancy. Pregnant mice without Bifidobacterium breve in their gut had a higher rate of complications including fetal growth restriction and fetal low blood sugar, and increased fetal loss. This gut bacteria seems to play a crucial role in prompting the placenta ...
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