What drives a mysterious sodium pump?
2026-02-12
Kyoto, Japan -- The enzyme Na⁺-NQR is a sodium pump that drives the respiration of many marine and pathogenic bacteria. Using redox reactions, the process of exchanging electrons between materials, it powers the transportation of sodium ions across the membrane, supporting the growth of the bacteria.
Yet there is a mystery behind this mechanism, as scientists have had trouble understanding exactly how the redox reactions are linked to sodium-pumping. In particular, the lack of structural information on the key intermediate states that form while the enzyme is operating has posed a major challenge; determining these structures is essential to understanding how the ...
Study reveals new cellular mechanisms that allow the most common chronic cardiac arrhythmia to persist in the heart
2026-02-12
Atrial fibrillation (AF), the most common chronic cardiac arrhythmia in clinical practice, is very challenging to treat once it becomes persistent, after which spontaneous return to normal rhythm becomes highly unlikely. A multidisciplinary study led by the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) and published in Circulation Research now provides a new perspective on why this arrhythmia can persist long-term, highlighting the key role of non-contractile cardiac cells.
AF has traditionally been viewed as a purely electrical disorder of cardiomyocytes—the heart’s contractile cells. However, the ...
Scientists discover new gatekeeper cell in the brain
2026-02-12
Ghent, 12 February 2026 – VIB and Ghent University researchers have identified and characterized a previously unknown cellular barrier in the brain, which sheds new light on how the brain is protected from the rest of the body. In a study published in Nature Neuroscience, the scientists also reveal a new pathway by which the immune system can impact the brain.
Prof. Roosmarijn Vandenbroucke (VIB–UGent Center for Inflammation Research): “These findings reveal how vulnerable and protectable the brain is, opening new perspectives for more targeted interventions in brain disorders.”
The ...
High blood pressure: trained laypeople improve healthcare in rural Africa
2026-02-12
In rural regions of Africa, high blood pressure often goes untreated because health centres are far away and there is a shortage of health professionals. A study in Lesotho shows that, with the help of a tablet app, villagers who have received training achieve better blood pressure control in their village community compared to normal treatment in healthcare facilities. The results provide the first robust data for an approach that could significantly improve access to blood pressure treatment in underserved regions. ...
Pitt research reveals protective key that may curb insulin-resistance and prevent diabetes
2026-02-12
Scientists at the University of Pittsburgh School of Medicine discovered a surprising new way the body can fight insulin resistance and diabetes – by boosting a special type of “good” immune cell in fat tissue.
Announced today in Nature Communications, the preclinical findings pave the path to develop a medication to treat and prevent type 2 diabetes, potentially replacing or supplementing GLP-1 weight maintenance drugs that lose effectiveness over time.
“One-third of our population is obese or overweight – over the next decade or so, ...
Queen Mary research results in changes to NHS guidelines
2026-02-12
Hundreds of people with advanced bladder cancer across the UK can now receive three rather than six chemotherapy cycles following research by Queen Mary University of London which has led to a change to NHS treatment guidelines. For people with the condition, this means fewer toxic side effects and a better quality of life during treatment.
Until recently, people with advanced bladder cancer routinely received between four to six cycles of intensive chemotherapy, followed by avelumab, a type of immunotherapy, as standard NHS care. ...
Sleep‑aligned fasting improves key heart and blood‑sugar markers
2026-02-12
Nighttime blood pressure dipped by 3.5%, heart rate dipped by 5% compared to controls
Given high adherence rate (nearly 90%), novel approach may be a more accessible non-pharmacological strategy for improving cardiometabolic health
‘It’s not only how much and what you eat, but also when you eat relative to sleep that is important’
CHICAGO --- A new Northwestern Medicine study has personalized overnight fasting by aligning it with individuals’ circadian sleep-wake rhythm — an important regulator of cardiovascular and metabolic function — without changing their caloric ...
Releasing pollack at depth could benefit their long-term survival, study suggests
2026-02-12
During 2026, new legislation – the result of an agreement between the UK Government and the European Union – is planned to come into force for recreational pollack fishing that limits catches to three fish per angler per day.
It will result in more fish being released after they are caught, but new research has suggested changing how that release happens could have a marked difference on the fisheries’ long-term sustainability.
Specifically, it suggests that releasing pollack closer to the depths they are normally caught could improve their chances of survival ...
Addictive digital habits in early adolescence linked to mental health struggles, study finds
2026-02-12
February 12, 2026 - New research following US adolescents ages 11–12 shows that problematic use of mobile phones, social media, and video games was associated with higher risks of mental health problems, sleep disturbance, and suicidal behaviors one year later. The study in the American Journal of Preventive Medicine, published by Elsevier, reveals that the links between problematic screen use and mental health are stronger than those previously reported for overall screen time and highlights the risks of addictive use.
Screen use increases rapidly during early adolescence, ...
As tropical fish move north, UT San Antonio researcher tracks climate threats to Texas waterways
2026-02-12
The National Science Foundation has awarded a UT San Antonio assistant professor of biology, health and the environment the distinguished Faculty Early Career Development Program (CAREER) award.
The assistant professor, Matthew Troia, will use the award to investigate how climate change and urbanization are affecting freshwater ecosystems by enabling exotic tropical fish species to expand northward.
“We hope our research will provide a deeper understanding of how biodiversity responds to increasing human impacts on the environment,” Troia said. “Our goal is to ...
Rich medieval Danes bought graves ‘closer to God’ despite leprosy stigma, archaeologists find
2026-02-12
Medieval Christians in Denmark showed off their wealth in death by buying prestigious graves: the closer to the church, the higher the price. Researchers used these gravesites to investigate social exclusion based on illness, by studying whether people with leprosy — a highly stigmatized disease culturally associated with sin — or tuberculosis were kept out of the higher-status areas. Unexpectedly, they found that people who were ill with stigmatized diseases were buried just as prominently as their peers.
“When we started this ...
Brexpiprazole as an adjunct therapy for cognitive dysfunction in schizophrenia
2026-02-12
Cognitive impairment, including decreased attention and memory, remains one of the most disabling aspects of schizophrenia, affecting social life of patients. However, no effective treatment has yet been established for it. Now, researchers have investigated the effect of adding brexpiprazole on cognitive function in patients with schizophrenia. The findings revealed that patients with schizophrenia receiving adjunctive brexpiprazole showed a meaningful improvement in information processing speed, without worsening psychiatric symptoms.
Schizophrenia ...
Applications of endovascular brain–computer interface in patients with Alzheimer's disease
2026-02-12
Background
Alzheimer's disease (AD) is the most common neurodegenerative disorder, characterized by progressive cognitive decline and memory impairment with an insidious and irreversible pathological process. As the global population ages, AD imposes a heavy burden on families and society: one new case is diagnosed every 3 seconds worldwide. Advanced-stage patients lose full self-care ability, and the associated medical and nursing costs account for over 1.3% of the global GDP.
Current clinical treatments mainly focus on symptomatic relief: cholinesterase inhibitors and the N-methyl-D-aspartate ...
Path Planning Transformers supervised by IRRT*-RRMS for multi-mobile robots
2026-02-12
In a study published in Robot Learning journal, researchers propose a new learning-based path planning framework that allows mobile robots to navigate safely and efficiently using a Transformer model. By learning from Improved RRT* with Reduced Random Map Size path-planning algorithms and combining this knowledge with a modified right-of-way rule, the system enables reliable navigation and replanning in dynamic multi-robot environments.
Autonomous mobile robots are increasingly used in factories, warehouses, and service environments to transport materials and perform repetitive tasks. To operate safely, robots must plan collision-free ...
Nurses can deliver hospital care just as well as doctors
2026-02-12
Nurses can safely deliver many services traditionally performed by doctors, with little to no difference in deaths, safety events, or how patients felt about their health, according to a new Cochrane review. In some cases, nurse-led care even outperformed doctor-led care.
Healthcare services are facing pressure due to an ageing population, complex health needs, long waiting lists, and doctor shortages. Receiving care from nurses, rather than doctors has been proposed as one way to improve access to hospital services for patients who ...
From surface to depth: 3D imaging traces vascular amyloid spread in the human brain
2026-02-12
Niigata, Japan - Researchers at Niigata University have used advanced three-dimensional (3D) imaging to reveal how amyloid β (Aβ) deposits spread along blood vessels in the human brain in cerebral amyloid angiopathy (CAA). By analyzing postmortem brain tissue, the team showed that vascular amyloid deposition is most prominent in surface arteries and extends continuously toward deeper vascular branches, providing insight into the spatial organization of amyloid pathology in CAA.
CAA is a cerebrovascular disorder ...
Breathing tube insertion before hospital admission for major trauma saves lives
2026-02-12
Trauma patients urgently requiring a breathing tube are more likely to survive if the tube is inserted before arriving at hospital compared to insertion afterwards, suggests a modelling study led by researchers at University College London (UCL) and the Severn Major Trauma Network.
The researchers found that prehospital emergency intubation of high-risk trauma patients could improve 30-day survival by 10.3%, and could save 170 lives each year in the UK.
The findings of the new artificial intelligence (AI)-supported analysis, published in The Lancet Respiratory Medicine, provides ...
Unseen planet or brown dwarf may have hidden 'rare' fading star
2026-02-12
One of the longest stellar dimming events ever observed was likely caused by the gigantic saucer-like rings of either an unseen brown dwarf or 'super-Jupiter' blocking its host star's light, astronomers say.
For decades the star – which sits 3,200 light-years from Earth and is about twice as big as our Sun – had been observed as stable, but at the end of 2024 it faded dramatically.
It then remained this way for more than nine months, far longer than is normal for an event like this, sparking confusion among researchers and prompting speculation as to what could have caused such an "extremely rare" phenomenon.
Now, in a new study published today in Monthly ...
Study: Discontinuing antidepressants in pregnancy nearly doubles risk of mental health emergencies
2026-02-11
Embargoed until 2:45 PM PST, February 11, 2026
Study: Discontinuing Antidepressants in Pregnancy Nearly Doubles Risk of Mental Health Emergencies
Las Vegas, NV – Pregnant patients who stopped taking their antidepressant medication during pregnancy were almost twice as likely to experience a mental health emergency compared with pregnant patients who continued taking their prescription, according to new research presented today at ...
Bipartisan members of congress relaunch Congressional Peripheral Artery Disease (PAD) Caucus with event that brings together lawmakers, medical experts, and patient advocates to address critical gap i
2026-02-11
WASHINGTON—The Society for Cardiovascular Angiography and Interventions (SCAI), the leading nonprofit medical society representing invasive and interventional cardiology, is proud to participate in the relaunch of the Congressional Peripheral Artery Disease (PAD) Caucus, organized by the PAD Pulse Alliance and hosted by Representatives Gus Bilirakis (R-FL) and Sheila Cherfilus-McCormick (D-FL).
The bipartisan event brought together physicians, patient advocates, and lawmakers to discuss current research and data, treatment, and urgent ...
Antibody-drug conjugate achieves high response rates as frontline treatment in aggressive, rare blood cancer
2026-02-11
Phase II study evaluates treatment for patients with blastic plasmacytoid dendritic cell neoplasm (BPDCN), a rare, aggressive blood cancer
The antibody-drug conjugate (ADC) pivekimab sunirine (PVEK) targets the CD123 antigen, which is overexpressed in BPDCN
PVEK monotherapy demonstrated strong responses, enabling ability to proceed with stem cell transplant for high-risk subgroup of patients with BPDCN
Seventy-five percent of patients with blastic plasmacytoid dendritic cell neoplasm (BPDCN) who were treated with the antibody-drug conjugate ...
Retina-inspired cascaded van der Waals heterostructures for photoelectric-ion neuromorphic computing
2026-02-11
Professor Zhen Zhang's research group at the State Key Laboratory of Bionic Interface Materials Science, University of Science and Technology of China, proposed and constructed a neuromorphic computing system based on a cascaded van der Waals heterostructure two-dimensional nanofluidic membrane, achieving light-driven electron-ion coupling to simulate neural signal transmission and neuromorphic visual information processing. The article was published as an open access Research Article in CCS Chemistry, the flagship journal of the Chinese ...
Seashells and coconut char: A coastal recipe for super-compost
2026-02-11
In the lush landscapes of tropical agriculture, two waste products—oyster shells from the sea and coconut shells from the trees—are being combined to solve a major headache for farmers: how to turn animal manure into high-quality compost faster and more effectively. A study recently published in Carbon Research reveals that a unique "Ca-modified biochar" can act as a powerful catalyst for the composting process. Developed by a research team at Hainan University, this new material helps transform pig manure and rice straw into stable, nutrient-rich humus, significantly boosting the ...
Feeding biochar to cattle may help lock carbon in soil and cut agricultural emissions
2026-02-11
Researchers have found that most biochar fed to dairy cows survives the digestive process and remains highly stable, meaning it could be applied to fields through manure and act as a long-term carbon storage solution. The findings provide new evidence that livestock systems could play a role in climate change mitigation.
The study, recently published in Biochar, investigated what happens to biochar after it passes through the digestive system of cattle. Biochar is a carbon-rich material produced ...
Researchers identify best strategies to cut air pollution and improve fertilizer quality during composting
2026-02-11
Scientists have uncovered practical strategies that can significantly reduce harmful air pollution from composting while improving the quality of organic fertilizers. The findings, based on a large global meta-analysis, provide new evidence to help farmers, waste managers, and policymakers adopt climate-smart composting practices.
The research, published in Environmental and Biogeochemical Processes, analyzed data from 135 scientific studies and 1,683 experimental observations worldwide. The study evaluated how different ...
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