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Researchers develop new strategy for improving inverted perovskite solar cells

2026-02-27
Regular perovskite solar cells (PSCs)—which place the electron-transport layer beneath the perovskite absorber and the hole-transport layer on top—have limitations with respect to large-scale manufacturing and stability. In contrast, inverted PSCs—which reverse the positions of the electron- and hole-transport layers—boast high power conversion potential and good compatibility with scalable solution processing techniques, making them a promising photovoltaic technology. Unfortunately, the performance and long-term stability of inverted ...

Yes! The role of YAP and CTGF as potential therapeutic targets for preventing severe liver disease

2026-02-27
Osaka, Japan – The long-term stasis of blood in the liver, known as chronic liver congestion, can lead to a range of diseases – some of which are fatal. However, identifying how liver congestion causes these diseases has remained unclear, causing difficulty in proposing the best treatment pathway. In a study recently published in Gastroenterology, Japanese researchers have identified a molecular pathway connecting liver congestion to liver fibrosis, portal hypertension, and liver tumorigenesis. This finding has important implications for potential therapies. Chronic liver congestion is also ...

Pancreatic cancer may begin hiding from the immune system earlier than we thought

2026-02-27
A new study suggests that pancreatic cancer may start preparing to “hide” from the immune system long before the disease becomes full-blown cancer. Researchers found that very early, precancerous cells in the pancreas don’t spread randomly, they gather into specific clusters and create small “neighborhoods” inside the tissue. These early cell groups also seem to communicate directly with nearby immune cells in ways that may weaken the body’s ability to fight them. Using advanced tools that characterize cells at the molecular level in tissue section of the pancreas, the team discovered that immune-suppressing signals appear at these ...

Robotic wing inspired by nature delivers leap in underwater stability

2026-02-27
Researchers have taken inspiration from nature to create a robotic wing that can sense and adapt to changes in water to deliver unparalleled stability.   Drawing on the adaptive movements of birds and fish, the wing senses disturbances in the flow of water and automatically changes its shape to adjust to these. The team, led by the University of Southampton, hope the soft robotics and e-skin they’ve pioneered could help close the gap in manoeuvrability and efficiency between robots and animals.   In ...

A clinical reveals that aniridia causes a progressive loss of corneal sensitivity

2026-02-27
Congenital aniridia is a rare disease caused, in most cases, by mutations in the PAX6 gene, which is essential for the development of ocular structures. Although the most visible feature is the total or partial absence of the iris, its effects go far beyond this, as those affected often experience focusing problems, photophobia, and various complications that may worsen over time. Now, a clinical study led by the Ocular Neurobiology Group at the Institute for Neurosciences (IN), a joint center of Miguel Hernández University ...

Fossil amber reveals the secret lives of Cretaceous ants

2026-02-27
Tiny insects trapped in amber could tell us a great deal about their roles in past ecosystems: pollinators, parasites, predators, and prey. But how many of the insects preserved alongside each other reflect interactions during life, and how many are just unlucky coincidences? Scientists in Spain scrutinized six key samples which preserve now-extinct insects unusually well, to try to learn more about the ants that lived at the same time as the dinosaurs. “Amber inclusions are representative of possible interactions between different organisms shaping the environment,” explained Dr Jose de la Fuente of the Institute for Game and Wildlife Research, Spain, lead author ...

Predicting extreme rainfall through novel spatial modeling

2026-02-27
Japan is an archipelago with diverse climate zones and complex topography that is prone to heavy rain and flooding. Add the growing effects of global warming, these disaster risks are heightened with an increased frequency and intensity of extreme precipitation events. Thus, predicting when and where these events might strike is crucial for future-proofing vulnerable infrastructure, especially in ...

The Lancet: First-ever in-utero stem cell therapy for fetal spina bifida repair is safe, study finds

2026-02-27
A phase 1 clinical trial published in The Lancet has shown that combining stem cell therapy with standard fetal surgery before birth is a safe and promising approach to treat myelomeningocele, a severe form of spina bifida. This is the first time live stem cells have been used on a fetus’ damaged spine, which could potentially lead to better health outcomes for babies compared to traditional fetal surgery. Spina bifida is a congenital condition in which the spinal cord does not develop properly, leaving part of it exposed. This can cause lifelong health challenges, including paralysis, difficulty walking, and issues with bladder and ...

Nanoplastics can interact with Salmonella to affect food safety, study shows

2026-02-26
URBANA, Ill. – Plastic products are ubiquitous in our food supply chain, shedding microplastics into every part of the human ecosystem. As they degrade, microplastics break down into even smaller fragments called nanoplastics — tiny particles that can affect biological molecules in ways not fully understood. In a new study, researchers at the University of Illinois Urbana-Champaign examined what happens when nanoplastics interact with Salmonella, potentially affecting food safety and human health. “Salmonella enterica is a major foodborne ...

Eric Moore, M.D., elected to Mayo Clinic Board of Trustees

2026-02-26
JACKSONVILLE, Florida — Eric Moore, M.D., medical director of Mayo Clinic International and chair of the Department of Otolaryngology in Rochester, was elected to the Mayo Clinic Board of Trustees at its quarterly meeting on Feb. 20.    "Dr. Moore is an internationally respected leader whose commitment to patients and strategic vision will be a tremendous asset to our Board of Trustees," says Gianrico Farrugia, M.D., president and CEO, Mayo Clinic. “His extensive experience and collaborative approach will help guide our strategic ...

NYU named “research powerhouse” in new analysis

2026-02-26
New York University is recognized as one of the 70 top research institutions consistently home to the world’s most-cited researchers over the past five years. The analysis of “research powerhouses,” led by the analytics company Clarivate, demonstrates where research impact is most concentrated. Since 2001, Clarivate has identified “highly cited researchers”—a group of scientists and social scientists whose research published over the last decade has demonstrated ...

New polymer materials may offer breakthrough solution for hard-to-remove PFAS in water

2026-02-26
Scientists are developing a new generation of polymer-based materials that could dramatically improve the removal of persistent “forever chemicals” from drinking water, according to a new review synthesizing recent advances in environmental remediation research. Per- and polyfluoroalkyl substances, known as PFAS, are a large class of human-made chemicals used in products ranging from firefighting foams to nonstick cookware and textiles. Their extreme stability allows them to persist in the environment and accumulate in water supplies, raising growing concerns about long-term ...

Biochar can either curb or boost greenhouse gas emissions depending on soil conditions, new study finds

2026-02-26
A new study reveals that biochar, a carbon rich material increasingly promoted for climate friendly agriculture, can have sharply different effects on greenhouse gas emissions depending on soil type and land use. The research shows that while biochar can significantly reduce nitrous oxide emissions in acidic upland soils, it may unexpectedly increase emissions in flooded rice paddies. Nitrous oxide is one of the most potent greenhouse gases, with a warming effect far greater than carbon dioxide over the long term. Agricultural soils are a major source of these emissions, making mitigation strategies critical for climate and food system sustainability. In the ...

Nanobiochar emerges as a next generation solution for cleaner water, healthier soils, and resilient ecosystems

2026-02-26
A new scientific review points to nanobiochar, an engineered carbon material derived from biomass, as a promising solution for some of the world’s most pressing environmental challenges. By shrinking conventional biochar to the nanoscale, researchers have created a material with dramatically increased surface area, reactivity, and environmental functionality, opening new possibilities for soil improvement, water treatment, and climate resilience. Biochar has long been used to improve soil quality and capture carbon, but the new analysis shows that nanoscale versions ...

Study finds more parents saying ‘No’ to vitamin K, putting babies’ brains at risk

2026-02-26
EMBARGOED FOR RELEASE UNTIL 4:00 P.M. ET, THURSDAY, FEBRUARY 26, 2026 Highlights: A new review of research has found the number of parents refusing vitamin K injections for their newborns is on the rise. Vitamin K is an essential vitamin that is naturally low in newborns. Vitamin K at birth is needed to help blood to clot. It is not a vaccine. Babies who do not receive vitamin K at birth are at a higher risk of life-threatening brain bleeds and long-term disability. While vitamin K refusal remains low, less than 1%, the review found rates of refusal in Minnesota ...

Scientists develop new gut health measure that tracks disease

2026-02-26
Scientists have identified a new way to distinguish healthy guts from diseased ones and track how some illnesses progress by measuring how gut bacteria interact with one another. According to a study published in Science, a collaboration between scientists at Rutgers University, Universidad de Granada in Spain and Princeton University found that healthy and diseased gut microbiomes behave like two distinct ecological states, driven not by individual microbes but by how entire bacterial communities compete and cooperate. “Instead ...

Rice gene discovery could cut fertiliser use while protecting yields

2026-02-26
UNDER EMBARGO UNTIL 19:00 GMT / 14:00 ET THURSDAY 26 FEBRUARY 2026 Rice gene discovery could cut fertiliser use while protecting yields Researchers from the University of Oxford, Nanjing Agricultural University, and Institute of Genetics and Developmental Biology (Chinese Academy of Sciences) have finally identified the master regulator in plants that balances root and shoot growth when nutrients are limited. In field trials, rice plants with an improved version of the gene had yield increases of up to 24%. The breakthrough, published today (26 February) in the prestigious ...

Jumping ‘DNA parasites’ linked to early stages of tumour formation

2026-02-26
A study published today in the journal Science reveals how jumping fragments of human DNA, a type of genetic parasite, destabilise the cancer genome. Unstable genomes are a fertile playground for cancer evolution, giving malignant cells more opportunities to grow, adapt and evade treatment.  The researchers analysed genome sequences from tumours with unusually high activity of LINE-1 (L1) elements, fragments of DNA which copy themselves and paste that copy into other locations within the genome.  Previously thought ...

Ultra-sensitive CAR T cells provide potential strategy to treat solid tumors

2026-02-26
Though CAR T cells have been effective against certain blood cancers, they have not been for solid tumors. Now, a new form of highly sensitive CAR T cells aims to overcome one of the biggest barriers in solid tumor immunotherapies – the way solid tumors lack a single, widely shared surface target. By engineering an ultra-sensitive receptor capable of detecting even the smallest amounts of the protein CD70, researchers report they were able to eradicate kidney, ovarian, and pancreatic tumors in preclinical models. The findings provide a potential strategy to treat a broad range of solid tumors. ...

Early Neanderthal-Human interbreeding was strongly sex biased

2026-02-26
When Neanderthals and ancient modern humans interbred, the pairings were mostly between male Neanderthals and female humans. This finding helps explain why Neanderthal ancestry present in most humans is unevenly distributed. Anatomically modern humans carry low levels of Neanderthal ancestry, but it is not evenly shared. When the genomes of Neanderthals and modern humans are compared, striking gaps known as “Neanderthal deserts” are revealed. These are large stretches of DNA in modern humans where Neanderthal genetic contributions are unusually rare. Such deserts appear across several chromosomes and are especially prominent on the X chromosome. According to Alexander Platt and ...

North American bird declines are widespread and accelerating in agricultural hotspots

2026-02-26
North American bird populations are not only declining, but they’re also shrinking faster with each passing year – particularly in regions shaped by intensive agriculture, according to a new study. Centuries of human impacts, including land use change, agricultural intensification, overexploitation, and pollution, have drastically reshaped the natural world, leading to population declines for many wildlife species worldwide. Although these declines are widely recognized, whether these losses are speeding up year over year, as well as the factors driving this potential acceleration, remain poorly understood. ...

Researchers recommend strategies for improved genetic privacy legislation

2026-02-26
U.S. policymakers addressing the public’s concerns about how genetic information could be used, in different insurance-related contexts, should consider several guiding questions, say authors of a new Policy Forum. Comprehensive genetic testing for both consumer and clinical use has led to the rise of genetic privacy laws like the Genetic Information Nondiscrimination Act (GINA), which bars health insurers and employers from using genetic information. As that 2008 Act was limited to health insurance, however, numerous states have since enacted bans on the discriminatory use of genetic information by other kinds of insurance (life, long-term care, ...

How birds achieve sweet success

2026-02-26
Anyone who has seen a hummingbird poking her beak deep into a trumpet creeper blossom, or a honeyeater using its brush-tipped tongue to extract nectar from eucalyptus flowers, has witnessed something that from a human perspective is rather remarkable. Although many bird species avoid sugar-rich foods, others survive almost entirely on sugar-rich nectar or fruit, processing massive sugar loads without developing the diseases that such diets cause in people and other animals. Groups including hummingbirds, sunbirds, ...

More sensitive cell therapy may be a HIT against solid cancers

2026-02-26
NEW YORK, NY (Feb. 26, 2026)--CAR T cell therapy has revolutionized the treatment of many blood cancers, but has shown little success against solid tumors, which account for over 85% of all cancers. Columbia researchers have now found that a new type of cell therapy—HIT cells, a cousin to CAR T with enhanced sensitivity—overcomes a major obstacle to treating solid tumors with cell therapy and can completely eliminate kidney, pancreatic, and ovarian cancers in mice. The research, conducted by investigators at the Columbia Initiative in Cell Engineering and Therapy (CICET), was published Feb. 26 in the journal Science. Michel Sadelain, director ...

Scientists map how aging reshapes cells across the entire mammalian body

2026-02-26
As we age with each passing year, we become more susceptible to chronic diseases like cancer, heart disease, and dementia. Scientists have long focused on fighting these conditions one at a time. Recently, however, many have begun to wonder whether they can slow aging itself. But to ward off age-related changes to the body, they must first understand what triggers them.   Now, in a study published in Science, researchers at The Rockefeller University have created the most comprehensive atlas yet of how aging affects thousands of cell subtypes across 21 ...
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