(Philadelphia, PA) – Calcium transport into and out of mitochondria – the powerhouses of cells – is central to cellular energy production and cell death. To maintain the balance of calcium within these powerhouses, cells rely on a protein known as the mitochondrial sodium-calcium exchanger, or NCLX. Now, in new research, scientists at the Lewis Katz School of Medicine at Temple University have discovered a novel regulator of NCLX activity, a protein called TMEM65, which helps move ...

Mental health is in crisis worldwide. While the neurosciences are advancing rapidly, psychiatry still struggles to diagnose and effectively treat many disorders. The Synapsy Center for Neuroscience and Mental Health Research at the University of Geneva, Switzerland, is launching a new international prize to reward those who bring these two worlds closer together. A new research model is needed Depression, schizophrenia, anxiety or bipolar disorders: psychiatric illnesses affect hundreds of millions of people worldwide and are among the leading causes of disability, suffering and mortality. Yet clinical advances remain limited. Many diagnoses ...

A new study maps how specific lactic acid bacteria can enhance both the flavour and nutritional quality of plant-based dairy alternatives. The findings may have wide-reaching perspectives for the further development of sustainable foods. Plant-based dairy alternatives – such as soy, oat, and almond drinks – are produced without animal ingredients for consumers seeking plant-based substitutes for milk and yoghurt. However, many of these products have the similar shortcomings: flavours that do not always appeal ...

A new paper in Nicotine & Tobacco Research, published by Oxford University Press, finds that a 2018 U.S. ban on smoking in public housing led to a reduction in hospitalizations for cardiovascular problems. Tobacco use and exposure to secondhand smoke is a leading cause of preventable death in the United States. Some 480,000 Americans die every year due to tobacco. While the prevalence of adults exposed to secondhand smoke decreased dramatically between 1988 and 2014 (from 87.5% to 25.2%), about 58 million non-smokers in the U.S. experience tobacco smoke, primarily at home. Beginning in the early 2000s, ...

MONTRÉAL, Québec, Canada, 8 April 2025 – In a powerful and deeply reflective Genomic Press Interview, published in Brain Medicine, Dr. Romina Mizrahi, Professor of Psychiatry at McGill University and Principal Investigator of the CaTS (Clinical and Translational Sciences) Lab at the Douglas Research Center, charts a new path forward in psychiatric research—one that begins at the molecular level. Harnessing the power of positron emission tomography (PET), Dr. Mizrahi’s work sheds light on the invisible workings of the human brain. Where traditional psychiatric diagnosis often relies on subjective symptom clusters, her approach integrates in-vivo imaging, ...

BARCELONA, Catalonia, Spain, 8 April 2025 – A new Brevia (peer-reviewed research report) published in Brain Medicine reveals that a single dose of the drug Osanetant, administered shortly after a traumatic event, significantly dampens fear expression in female mice. The findings provide strong preclinical support for using Nk3R antagonism as a sex-specific, time-sensitive intervention to reduce the risk of posttraumatic stress disorder (PTSD). Targeting fear memory at its roots Fear memory is a core feature of PTSD, especially when neutral cues become emotionally ...

For hundreds of years, the Amazon has been exploited for its gold. Today, the precious metal is just as sought after, but the remaining tiny gold particles are much harder to find. Mining often happens in artisanal and small-scale mining operations that release mercury (Hg) into the air, polluting the environment and harming human health. An international team of researchers has now examined tree rings of species native to the Peruvian Amazon to determine if trees could be used to show approximately where and when atmospheric mercury was released. “We show that Ficus insipda tree cores can be used as a biomonitor for characterizing ...

The research team led by Dr. Jongwon Yoon, Dr. Jeongdae Kwon, and Dr. Yonghoon Kim from the Energy & Environmental Materials Research Division at the Korea Institute of Materials Science (KIMS), has successfully developed the world’s first ammonia (NH₃) gas sensor based on a copper bromide (CuBr) film that can be fabricated through a simple solution process at low temperatures. This breakthrough technology not only enables sensor flexibility, ultra-sensitivity, and high selectivity but also significantly reduces manufacturing costs. Ammonia gas sensors detect airborne ammonia and are utilized in indoor and outdoor ...

Hot flashes, mood swings, weight gain and insomnia are all signs of hormonal changes and symptoms of menopause, when a woman no longer has menstrual cycles. They can also signal perimenopause, when the body is preparing for this next season of life. “Perimenopause is when the menstrual cycle has started to change, and it is persistent,” explained Lauren Baker, DO, an obstetrics and gynecology physician at The Ohio State University Wexner Medical Center and certified practitioner with the Menopause Society. “The formal definition is periods fluctuate by at least seven days for at least 10 months.” A new survey by Ohio State ...

SINGAPORE – Researchers from the Agency for Science, Technology and Research (A*STAR) and the National Healthcare Group (NHG) have jointly pioneered an innovative imaging technique combining Multispectral Optoacoustic Tomography (MSOT) with artificial intelligence (AI) that could significantly improve the diagnosis and treatment of basal cell carcinoma (BCC), the most common form of skin cancer worldwide. This advanced technique uses photoacoustic imaging (PAI), enhanced by an automated segmentation algorithm, to provide real-time, high-resolution, three-dimensional (3D) images of skin tumours. By accurately mapping tumour boundaries, ...

New Australian technology is set to transform the way that gastrointestinal cancers are detected and treated with precise, minimally invasive surgery. Backed by the Federal Government’s Economic Accelerator (AEA) Ignite Grant, researchers from the University of South Australia (UniSA) are using quantum technology to develop a first-of-its-kind laparoscopic probe that will allow surgeons to accurately map the spread of tumours. The technology has the potential to improve cancer survival rates and patient quality of life worldwide. Led by Dr Nicole Dmochowska from UniSA’s ...

FOR IMMEDIATE RELEASE Physicians have long observed a mystifying phenomenon: After a bout of infection or an autoimmune disease flare-up, some people experience prolonged mood swings, emotional dysregulation, and changes in behavior. But the precise connection between inflammation, mood, and behavior has remained elusive.  Now, two new studies from Harvard Medical School and Massachusetts Institute of Technology, published April 7 in Cell, detail the steps of an intricate brain-immune crosstalk that accounts for this long-known but poorly understood observation. The work, conducted ...

Researchers have successfully demonstrated the UK’s first long-distance ultra-secure transfer of data over a quantum communications network, including the UK’s first long-distance quantum-secured video call. The team, from the Universities of Bristol and Cambridge, created the network, which uses standard fibreoptic infrastructure, but relies on a variety of quantum phenomena to enable ultra-secure data transfer. The network uses two types of quantum key distribution (QKD) schemes: ‘unhackable’ encryption keys hidden inside particles of light; and distributed entanglement: a phenomenon that causes quantum particles to be intrinsically ...

As many as one in 3,000 people could be carrying a faulty gene that significantly increases their risk of a punctured lung, according to new estimates from Cambridge researchers. Previous estimates had put this risk closer to one in 200,000 people. The gene in question, FLCN, is linked to a condition known as Birt-Hogg-Dubé syndrome, symptoms of which include benign skin tumours, lung cysts, and an increased risk of kidney cancer. In a study published today in the journal Thorax, a team from the University of Cambridge examined data from UK Biobank, the 100,000 Genomes Project, and East London Genes & Health – three large genomic datasets encompassing more than ...

Thinking creatively, solving complex problems, and working in teams… all add up to Design Thinking (DT). A study conducted by the Escuela Superior Politécnica del Litoral (ESPOL) and Ghent University provides a step-by-step guide for teaching this methodology as a university course. The main objective of this study is to share the implementation of DT in the first year of all undergraduate programs at ESPOL, considering that previous research has shown that this course fosters essential DT skills in a world of constant change, allowing students to build their own knowledge through experiential learning. In practice, this study ...

The American College of Cardiology is recognizing the 2025 winners of its Young Investigator Awards, which took place at the ACC’s Annual Scientific Session (ACC.25) in Chicago. The Young Investigator Awards competition invites promising, young scientific investigators to present their cutting-edge research. The finalists competed in three categories: Basic and Translational Science, Clinical Investigations and Outcomes Research. This year’s awardees are: Young Investigator Awards in Basic ...

Embargoed for release until 5:00 p.m. ET on Monday 7 April 2025    Follow @Annalsofim on X, Facebook, Instagram, threads, and Linkedin         Below please find summaries of new articles that will be published in the next issue of Annals of Internal Medicine. The summaries are not intended to substitute for the full articles as a source of information. This information is under strict embargo and by taking it into possession, media representatives are committing to the ...

Columbus, OH; Cleveland, OH, April 7, 2025 – CAS, a division of the American Chemical Society specializing in scientific content and knowledge management, and Cleveland Clinic, an academic health system with a global footprint, announced plans for a strategic collaboration that will unite the organizations’ unique expertise, technology, and data capabilities to fuel clinical research.     During the Cleveland Discovery & Innovation Forum, an event highlighting cutting-edge healthcare and life sciences research, the two global organizations announced that their collaboration’s ...

The Food and Drug Administration (FDA) collects user fees from drug and medical device companies to fund its work ensuring the safety of these products. Creating a similar program that collects fees from food companies could generate much-needed resources to strengthen the FDA’s oversight of foods, according to a new legal and policy analysis published in the journal Health Affairs. “The FDA is persistently understaffed and underfunded, hampering its ability to ensure the safety of our country’s food supply,” said Jennifer Pomeranz, associate professor of public health policy and management at NYU ...

While Food is Medicine programs are successfully helping patients manage their health, many initiatives are small-scale pilots, providing treatment to several hundred or several thousand patients. Results of these studies have demonstrated that these nutrition-based food prescription programs improve a range of health outcomes for patients with diet-sensitive conditions, while also potentially saving in medical costs, suggesting wider implementation and investment would lead to long-term savings and a healthier population. To ...

Sarah Sjöström, MSN, RN, ACNP-BC, has been promoted to chief nursing officer at Hebrew SeniorLife.  Sjöström joined Hebrew SeniorLife in 2010 as a staff nurse, later became director of nursing in the Medical Acute Care Unit, was promoted to associate chief nursing officer in 2017, and gained the vice president of ancillary services responsibilities in 2023.   She is co-chair of Hebrew SeniorLife’s Age-Friendly Committee and, through that work and as associate chief nursing officer, has championed quality of care and age-friendly practices across the organization. In 2021, she received a John A. Hartford Foundation scholarship to participate in the ...

When are you most forthcoming with life updates? And when are you the most transparent about exactly what those updates are? For most folks — show of hands, please — it’s when things are going well. Sharing our wins is in our nature; our losses, typically, not so much. Not surprisingly, governments are similarly inclined. Yet, it turns out, broad government transparency not only breeds goodwill, begetting still more transparency — it can change lives for the better. Researchers Sarah Anderson and Mark Buntaine, of UC Santa Barbara’s Bren School of Environmental Science & Management, and colleagues ...

Airborne dust pollution  is a growing problem for residente of Utah and other Western states, especially with the exposed lakebed of Great Salt Lake potentially becoming more hazardous as the lake dries. Natural dust blows from the Great Basin and settles along the western edge of the Wasatch Front, Utah’s major population center, and the surrounding mountains. While airborne, the dust mixes with local human-made materials, potentially contaminating the nearby watershed and resulting in other negative consequences, according ...

Stephen Hauser Wins Breakthrough Prize for Role in Redefining MS UCSF luminary played a pivotal part in identifying cause of multiple sclerosis, leading to a new generation of game-changing therapies. Neuro-immunologist Stephen Hauser, MD, whose maverick thinking transformed the treatment landscape for patients with multiple sclerosis (MS), has received the 2025 Breakthrough Prize in Life Sciences. Hauser, a UCSF professor of neurology and director of the Weill Institute for Neurosciences, was recognized April 5 for overturning ...

Mass General Brigham investigators have linked difficult early life experiences with reduced quality and quantity of the white matter communication highways throughout the adolescent brain. This reduced connectivity is also associated with lower performance on cognitive tasks. However, certain social resiliency factors like neighborhood cohesion and positive parenting may have a protective effect. Results are published in Proceedings of the National Academy of Sciences (PNAS).  White matter are the communication highways that allow the brain networks to carry out the necessary functions for cognition and behavior. ...