Timing is everything: Finding treatment windows in genetic brain disease
2025-08-19
A Yale research team has created a new computer tool that can pinpoint when exactly genes turn on and off over time during brain development — a finding that may one day help doctors identify the optimal window to deploy gene therapy treatments.
Dubbed “chronODE,” the tool uses math and machine learning to model how gene activity and chromatin (the DNA and protein mix that forms chromosomes) patterns change over time. The tool may offer a variety of applications in disease modelling and basic genomic research and perhaps lead to future therapeutic uses.
“Basically, we ...
MSU scientist partners on biofuel policy for a carbon-neutral agricultural future
2025-08-19
MSU has a satellite uplink/LTN TV studio and Comrex line for radio interviews upon request.
Why this matters:
Biofuels have long been regarded as a key tool for reducing reliance on fossil fuels, but current policies often overlook the carbon benefits of sustainable farming practices. Therefore, farmers could be rewarded for adopting practices such as no-till farming, crop rotation, cover cropping, variable rate input, precision conservation and emerging climate-smart technologies like biochar and enhanced rock weathering.
Climate-smart ...
Building blocks and quantum computers: New research leans on modularity
2025-08-19
What do children’s building blocks and quantum computing have in common? The answer is modularity. It is difficult for scientists to build quantum computers monolithically – that is, as a single large unit. Quantum computing relies on the manipulation of millions of information units called qubits, but these qubits are difficult to assemble. The solution? Finding modular ways to construct quantum computers. Like plastic children’s bricks that lock together to create larger, more intricate structures, ...
Clinical and medical-education pioneer to forge links throughout HonorHealth Research Institute, emphasizing disease prevention
2025-08-19
SCOTTSDALE, Ariz. — Aug. 19, 2025 — Laura Goetz, M.D., MPH, one of the nation’s leading advocates for moving new translational laboratory discoveries into clinical practice where they can immediately benefit patients, has been named HonorHealth Research Institute’s first Research Director of Precision Medicine.
In her new position, within the Research Institute’s Center for Clinical Investigations, Dr. Goetz will develop protocols emphasizing disease prevention for all five of the Institute’s research divisions: Oncology, Cardiovascular, Neuroscience, Bariatric/GI, and Multispecialty, which includes the Institute’s newest research efforts. ...
Breakthrough in understanding amylin could pave way for next generation of weight loss drugs
2025-08-19
OKLAHOMA CITY – Amylin, a hormone that controls appetite and blood sugar by activating three different receptors in the brain, could be the basis for the next blockbuster obesity drugs. A University of Oklahoma study published today in the journal Science Signaling reveals a new understanding of how amylin receptors react upon being activated, an advancement that will be crucial to the field of drug development.
“This paper shows the new biochemical and pharmacological methods we developed that will enable the field, for the first time, to understand exactly what ...
UC Davis study reveals alarming browser tracking by GenAI assistants
2025-08-19
A new study led by computer scientists at the University of California, Davis, reveals that generative AI browser assistants collect and share sensitive data without users’ knowledge. Stronger safeguards, transparency and awareness are needed to protect user privacy online, the researchers said.
A new brand of generative AI, or GenAI, browser extensions act as your personal assistant as you surf the web, making browsing easier and more personalized. They can summarize web pages, answer questions, translate text and take notes.
But ...
GSA Guide offers strategies for helping patients make better health care choices
2025-08-19
“Why bother? At my age, breast cancer is the least of my worries,” says a patient in the opening vignette of “Helping Patients Make Health Care Decisions,” the latest publication from the Gerontological Society of America. This new guide equips health care providers with essential strategies to support informed, value-based decision-making with their older patients, recognizing the many factors that influence how individuals approach their health care.
As the population ages, providers ...
New study identifies key conditions for amplifying student voices in schools
2025-08-19
UNIVERSITY PARK, Pa. — Creating meaningful opportunities for students to help shape their own education isn’t simply a matter of inviting them to speak up. According to new research led by Penn State College of Education Professor Dana Mitra, it requires a careful balance of teacher mindsets, relationships and practical skills — what the study terms cognitive mindsets, emotive “heartsets” and intention-building skillsets.
The study, published in Teachers College Record: The Voice of Scholarship in Education and funded by the Bill & Melinda Gates Foundation, examined how “student voice practices” (SVPs) take root in schools. SVPs ...
SwRI-led Webb Telescope survey discovers new moon orbiting Uranus
2025-08-19
SAN ANTONIO — August 19, 2025 — Southwest Research Institute led a James Webb Space Telescope (JWST) survey, discovering a previously unknown tiny moon orbiting Uranus. A team led by SwRI’s Dr. Maryame El Moutamid discovered the small object in a series of images taken on Feb. 2, 2025, bringing Uranus’ total moon count to 29.
“As part of JWST’s guest observer program, we found a previously unknown satellite of the ice giant, which has been provisionally designated S/2025 U 1,” said El Moutamid, a lead scientist in SwRI’s Solar System Science and Exploration Division in Boulder, Colorado. “This object, by far the smallest ...
Study of overdose dashboard in Cayuga County shows value of real-time data
2025-08-19
ITHACA, N.Y. - As overdoses from fentanyl and opioids continue to rise, many communities have created interactive overdose dashboards showing data trends and community resources to help with substance abuse.
However, there’s not much research looking at how effective these dashboards are at helping public health officials make data-driven decisions, especially in rural areas.
Researchers from Cornell University are filling that gap.
They collaborated with Cayuga County Mental Health ...
UAlbany study finds more new doctors are choosing to stay in New York
2025-08-19
ALBANY, N.Y. (Aug. 19, 2025) — The percentage of physicians who go on to practice in New York State after completing their residency training continues to climb. A recent analysis conducted by the Center for Health Workforce Studies at the University at Albany’s College of Integrated Health Sciences examined findings from their most recent New York Resident Exit Survey. They found that 52% of newly trained physicians with confirmed practice plans reported plans to stay in New York, ...
Baycrest leader elected to Canadian Academy of Health Sciences
2025-08-19
Toronto, August 19, 2025 - Baycrest congratulates Dr. Allison Sekuler, President and Chief Scientist of the Baycrest Academy for Research and Education and the Centre for Aging + Brain Health Innovation powered by Baycrest (CABHI), on being elected a Fellow of the Canadian Academy of Health Sciences (CAHS), one of the highest honours in the Canadian health sciences community.
Election to the CAHS Fellowship recognizes exceptional leadership, scientific achievement and a commitment to advancing health outcomes for Canadians.
“Election to the Canadian Academy of Health Sciences is one of the highest honours ...
Restricted blood flow speeds tumor growth by aging the immune system
2025-08-19
Cutting off blood flow can prematurely age the bone marrow, weakening the immune system’s ability to fight cancer, according to a new study from NYU Langone Health.
Published online August 19 in JACC-CardioOncology, the study showed that peripheral ischemia–restricted blood flow in the arteries in the legs–caused breast tumors in mice to grow at double the rate seen in mice without restricted flow. These findings build on a 2020 study from the same team that found ischemia during a heart attack to have the same effect.
Ischemia ...
Exploring long term, complex biodiversity change in Scotland’s landscapes
2025-08-19
Exploring long term, complex biodiversity change in Scotland’s landscapes
Despite growing concern about biodiversity loss due to the ongoing biodiversity and climate crises, scientists have relatively little understanding of the pace and complexity of biodiversity change over preceding millennia.
To address this challenge, ecologists from the University of Edinburgh, University of St Andrews and National Tsing Hua University, Taiwan have applied a recently developed technique to explore how plant biodiversity ...
Radio waves amp up smell without surgery or chemicals
2025-08-19
WASHINGTON, Aug. 19, 2025 — Our sense of smell is more important than we often realize. It helps us enjoy food, detect danger like smoke or gas leaks, and even affects memory and emotion. Many people — especially after COVID-19, aging, or brain injury — suffer from a loss of smell. However, there are very few effective treatments, and those that exist often use strong scents or medicines that cause discomfort in patients.
In a study published this week in APL Bioengineering, by AIP Publishing, researchers ...
A serve with serious swerve
2025-08-19
WASHINGTON, Aug. 19, 2025 — One of the world’s most popular sports, badminton is played by around 220 million people across the globe. As with other racket sports, a well-executed serve can establish a consequential advantage at the start of a rally.
The “spin serve” was introduced by a Danish player at the Polish Open 2023 badminton tournament. The technique adds pre-spin before the racket touches the shuttlecock, whose natural spin is typically determined by its feathers’ inclination ...
Differential use of depression and anxiety medications in adults with a history of cancer
2025-08-19
About The Study: In this study, cancer survivors were significantly more likely to take medications for depression and anxiety compared with noncancer survivors, underscoring the importance of mental health in cancer. However, the findings suggested disparities associated with this, with non-Hispanic Black patients exhibiting decreased use.
Corresponding Author: To contact the corresponding author, Nosayaba Osazuwa-Peters, BDS, PhD, MPH, CHES, email nosa.peters@duke.edu.
To access the embargoed study: Visit our For ...
Study reveals how HPV reprograms immune cells to help cancer grow
2025-08-19
The most common cancer-causing strain of human papillomavirus (HPV), HPV16, undermines the body’s defenses by reprogramming immune cells surrounding the tumor, according to new research from the Keck School of Medicine of USC. In mice, blocking this process boosted the ability of experimental treatments for HPV to eliminate cancer cells. The results were just published in the Journal for ImmunoTherapy of Cancer.
HPV16 causes more than half of cervical cancer cases and roughly 90% of HPV-linked throat cancers. It can be neutralized with the ...
Epigenetic aging markers predict colorectal cancer risk in postmenopausal women
2025-08-19
“Our findings contribute to better understanding of the role of a pre-diagnostic epigenetic aging biomarker and its interplay with lifestyles in CRC carcinogenesis, informing risk stratification strategies for aged individuals.”
BUFFALO, NY — August 19, 2025 — A new research paper was published in Volume 17, Issue 7 of Aging (Aging-US) on July 7, 2025, titled “Epigenetic age and accelerated aging phenotypes: a tumor biomarker for predicting colorectal cancer.”
In this study led by Su Yon Jung from the University of California, ...
A comprehensive survey of orbital edge computing: Systems, applications, and algorithms
2025-08-19
Recently, a team from the Space-based Intelligence Laboratory at the Innovation Academy for Microsatellites of Chinese Academy of Sciences, reviewed the recent development trends in orbital edge computing. They conducts a comprehensive survey and analysis of OEC's system architecture, applications, algorithms, and simulation tools, providing a solid background for researchers in the field. By discussing OEC use cases and the challenges faced, potential research directions for future OEC research are proposed.
The team published ...
Targeting high agility aviation electro-mechanical actuation: ADRC emerges as key to high-dynamic servo drives
2025-08-19
With the rapid development of electrified transportation, there has been a growing demand for high-dynamic and high-precision Electro-Mechanical Actuation (EMA) servo drives in the aviation field. However, EMA applications face more severe multi-source disturbances than industrial servo drives. This issue has received extensive attention in the aviation field. Active Disturbance Rejection Control (ADRC) is a novel control structure that employs disturbance suppression. ADRC does not rely on an accurate model, exhibiting robustness to uncertainties.
Recently, ...
How Zelda and Studio Ghibli inspire happiness and purpose
2025-08-19
(Toronto, August 18, 2025) A new study published in JMIR Serious Games by JMIR Publications reveals that playing the open-world video game The Legend of Zelda: Breath of the Wild and watching Studio Ghibli films can significantly improve young people’s overall happiness and sense of purpose in life.
Led by researchers from Imperial College London, Kyushu Sangyo University, and Georgia State University, the exploratory randomized controlled study, titled “Effects of The Legend of Zelda: Breath of the Wild and Studio Ghibli Films on Young People’s Sense of Exploration, Calm, Mastery and Skill, Purpose and Meaning, and Overall Happiness ...
AI hybrid strategy improves mammogram interpretation
2025-08-19
OAK BROOK, Ill. – A hybrid reading strategy for screening mammography, developed by Dutch researchers and deployed retrospectively to more than 40,000 exams, reduced radiologist workload by 38% without changing recall or cancer detection rates. The study, which emphasizes AI confidence, was published today in Radiology, a journal of the Radiological Society of North America (RSNA).
“Although the overall performance of state-of-the-art AI models is very high, AI sometimes makes mistakes,” said Sarah D. Verboom, M.Sc., a doctoral candidate in the Department of Medical Imaging ...
Texas Children’s provides new breakthrough treatment for patient with rare neurological disorder
2025-08-19
HOUSTON (AUGUST 19, 2025) – Texas Children’s is pleased to announce that a three-year-old girl has been successfully treated with the first-ever FDA-approved gene therapy treatment for AADC deficiency.
Aromatic l-amino acid decarboxylase (AADC) deficiency is an extremely rare, inherited neurological disorder that prevents the brain from producing dopamine and serotonin — essential chemicals for controlling movement, mood and basic nervous system functions. The literature reports approximately 350 people with this condition worldwide. Historically, there was no cure or approved treatment for AADC, and the shortened life expectancy was estimated between ...
Pneumococcal vaccine trial aims to provide more protection to babies
2025-08-19
A new vaccine for pneumococcal disease will be tested under an international trial aiming to provide greater protection to babies against the common infection that causes pneumonia, sinusitis and meningitis.
The Murdoch Children’s Research Institute (MCRI) led study is evaluating a promising vaccine developed to protect against 21 strains of pneumococcus, up from the current 13 strains included in the National Immunisation Program (NIP).
The Melbourne arm of the randomised controlled trial is recruiting 50 families with heathy two month olds who haven’t had ...
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