Temporary benefit for immune system in early HIV treatment, but dysregulation returns
2025-11-08
Despite effective HIV medication, the immune system of people with HIV remains disrupted in the long term. Researchers at Amsterdam UMC investigated whether this dysregulation can be prevented by starting HIV medication immediately after infection – i.e. within a few days. They saw that six months after this early treatment, the immune system did indeed work as in people without HIV. But in the longer term, the immune system was disrupted again. This is shown by research by Amsterdam UMC, published in the journal EBioMedicine.
Early treatment protects immune systems only temporarily
For this study, the scientists examined ...
Chronic kidney disease is now the ninth leading cause of death
2025-11-08
Record numbers of men and women globally are now estimated to have reduced kidney function, a new study shows. Figures rose from 378 million people with the disease in 1990 to 788 million in 2023 as the world population grew and aged, making it for the first time a top 10 cause of death worldwide.
Led by researchers at NYU Langone Health, the University of Glasgow, and the Institute for Health Metrics and Evaluation (IHME) at the University of Washington, the analysis explored the rise of the illness, in which the kidneys gradually lose their ability to filter waste and excess fluid from the blood. Mild cases may have no symptoms while the most severe stages ...
Chronic kidney disease has more than doubled since 1990, now affecting nearly 800 million people worldwide
2025-11-08
In 2023, chronic kidney disease (CKD) was the 9th-leading cause of death worldwide, responsible for nearly 1.5 million deaths.
Unlike most other leading causes of death, CKD mortality rates continue to rise, signaling a growing global health crisis.
In 2023, CKD ranked as the 12th-leading cause of disability worldwide and the 7th-leading driver of cardiovascular deaths. Kidney dysfunction alone accounted for almost 12% of all global cardiovascular deaths.
Diabetes, obesity, and high blood pressure remain the top drivers of CKD, alongside dietary risks and environmental factors.
SEATTLE, Wash. – Nov. 7, ...
Participant experiences in a kidney failure care intervention in the navigate-kidney study
2025-11-08
About The Study: The results of this study suggest that community health workers played a vital role in improving patient engagement, emotional wellbeing, and self-efficacy, suggesting their integration into dialysis care teams may enhance holistic, patient-centered care.
Corresponding Author: To contact the corresponding author, Lilia Cervantes, MD, email Lilia.Cervantes@cuanschutz.edu.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamanetworkopen.2025.48506)
Editor’s ...
Community health worker support for Hispanic and Latino individuals receiving hemodialysis
2025-11-08
About The Study: In this randomized clinical trial, a culturally tailored community health worker intervention modestly lowered interdialytic weight gain and improved dialysis adherence and patient activation among Hispanic and Latino patients with hemodialysis-dependent kidney failure.
Corresponding Author: To contact the corresponding author, Lilia Cervantes, MD, MSc, email lilia.cervantes@cuanschutz.edu.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamainternmed.2025.5305)
Editor’s Note: Please see the article for additional information, including other authors, author ...
Scientists unveil new strategies to balance farming and ecological protection in Northeast China
2025-11-07
As China’s most important grain-producing region, Northeast China plays a vital role in safeguarding national food security. Yet this agricultural powerhouse faces a growing dilemma: how to maintain high crop yields while protecting the fragile ecosystems that sustain long-term productivity. A new study published in Agricultural Ecology and Environment identifies the key conflicts between agricultural expansion and ecological protection in the region and proposes integrated strategies to achieve a more sustainable balance.
Over the past four decades, Northeast China’s farmlands ...
UT Health San Antonio scientist helps shape new traumatic brain injury guidelines
2025-11-07
SAN ANTONIO, Nov. 7, 2025 – Traumatic brain injury, or TBI, affects millions of Americans each year, often resulting in long-term health challenges. New national recommendations are now paving the way for more effective short- and long-term care for patients with TBI.
Monica Verduzco-Gutierrez, MD, a physiatrist with UT Health San Antonio, the academic health center of The University of Texas at San Antonio, and professor and chair of the Department of Physical Medicine and Rehabilitation at UT San Antonio’s Long School of Medicine, served on the National Academies of Sciences, ...
Rising nitrogen and rainfall could supercharge greenhouse gas emissions from the world’s largest grasslands
2025-11-07
As the planet warms and rainfall patterns shift, new research suggests that the world’s largest grassland region may become a growing source of nitrous oxide, a greenhouse gas nearly 300 times more potent than carbon dioxide.
A team of scientists led by Dr. Shuping Qin from the Chinese Academy of Sciences examined how soil and climate conditions control the process of denitrification, a key microbial pathway that converts nitrogen compounds in soil into gases including nitrous oxide (N₂O) and nitrogen gas (N₂). Their study, recently published in Environmental and Biogeochemical Processes, is the first to map how denitrification responds ...
Study uncovers glomerular disease outcomes across the lifespan
2025-11-07
Houston, TX (November 7, 2025) — New research reveals that contrary toconventional belief, primary glomerular diseases are not necessarily benign for children and young adults. In fact, some subsets of children and young adults may experience faster kidney function decline than older patients. The findings will be presented at ASN Kidney Week 2025 November 5–9.
Direct comparisons of outcomes between adult and pediatric patients with primary glomerular diseases are rare—including minimal change disease (MCD), focalsegmental ...
Sotagliflozin outperforms dapagliflozin for reducing salt- sensitive hypertension and kidney injury in rats
2025-11-07
Houston, TX (November 7, 2025) — Sodium-glucose co-transporter 2 (SGLT2) inhibitors, initially developed to treat type 2 diabetes, have significant heart- and kidney- protective effects. In the kidney, SGLT2 reabsorbs approximately 97% offiltered glucose in the S1 and S2 segments of the proximal tubule, while SGLT1reabsorbs the remainder in the S3 segment. In research conducted in rats, investigators found that dual inhibition of SGLT1 and SGLT2 more effectively reduces salt-sensitive hypertension and kidney injury than SGLT2 inhibition alone. The findings will be presented ...
Trial analysis reveals almost all adults with hypertensive chronic kidney disease would benefit from intensive blood pressure lowering
2025-11-07
Houston, TX (November 7, 2025) — An analysis of the Systolic Blood Pressure Intervention Trial (SPRINT) indicates that nearly all adults with chronic kidney disease (CKD) would have benefits that outweigh the harm from a systolic blood pressure target of <120 mm Hg compared with a target of <140 mm Hg. Thefindings will be presented at ASN Kidney Week 2025 November 5– 9.
In a benefit-harm trade-off analysis of 2,012 participants with CKD, investigators found that when predicting individualized treatment effects for multiple outcomesand simulating ...
A husband’s self-esteem may protect against preterm births, study finds
2025-11-07
A husband’s optimism and confidence may play a crucial, if often unseen, role in helping babies arrive healthy and on time.
A new study from University of California Merced psychology researchers found that when married fathers reported higher levels of resilience — a quality that includes traits such as optimism, self-esteem, and perceived social support — their partners showed lower levels of inflammation during pregnancy and carried their babies longer.
“This is one of the first studies to show that a father’s inner strengths, such as his optimism and ability to cope with challenges, can ripple through the family in measurable, ...
Michigan State University's James Madison College receives over $1 million to launch civic education academy
2025-11-07
MSU has a satellite uplink/LTN TV studio and Comrex line for radio interviews upon request.
Images
EAST LANSING, Mich. – To mark the 250th anniversary of the Declaration of Independence next July, Michigan State University’s James Madison College has plans to launch summer programs for Michigan high school students and teachers that explore America’s founding principles.
A three-year grant, totaling $1.3 million from the U.S. Department of Education, will fund the James Madison College Academy for Civic Education, or ACE, offering intensive seminars built around primary sources like the U.S. Constitution, Federalist Papers, works ...
White paper on recovering from burnout through mentoring released by University of Phoenix College of Doctoral Studies
2025-11-07
University of Phoenix College of Doctoral Studies announces the publication of a new white paper, “Recovering from Burnout Through Mentoring,” authored by Carla M. Harris, Ed.D., and Sandra Sessoms-Penny, Ed.D, both Fellows at the University of Phoenix Center for Organizational Wellness, Engagement, and Belonging (CO-WEB). The paper examines how structured mentorship can support employees experiencing burnout and offers actionable guidance for organizations and leaders to foster resilience and engagement.
Grounded in current research and insights from the University’s Career Optimism Index® study, the authors note that employee burnout ...
Defunct Pennsylvania oil and gas wells may leak methane, metals into water
2025-11-07
UNIVERSITY PARK, Pa. — In the dense forests of northwestern Pennsylvania, hundreds of thousands of retired oil and gas wells — some dating back to the mid-1800s, long before modern construction standards — dot the landscape, according to geochemists in Penn State’s College of Earth and Mineral Sciences who recently led a study in the region. Left uncapped and exposed to air and erosion, they break down, leaching harmful chemicals into the atmosphere and, the researchers reported, into the groundwater.
Led by Susan L. Brantley, ...
Kessler Foundation’s John DeLuca, PhD, honored with Reitan Clinical Excellence Award from National Academy of Neuropsychology
2025-11-07
East Hanover, NJ – Nov. 7, 2025 – John DeLuca, PhD, of Kessler Foundation received the 2025 Reitan Clinical Excellence Award from the National Academy of Neuropsychology (NAN) at its annual conference today. This honor recognizes individuals who have made significant contributions to the clinical practice of neuropsychology, influencing methods, settings, and training in ways that benefit both the profession and its clients.
Dr. DeLuca is senior vice president of Research and Training at the Foundation and a recognized leader in the field of neuropsychology. ...
Discordance in creatinine- and cystatin C–based eGFR and clinical outcomes
2025-11-07
About The Study: In the Chronic Kidney Disease Prognosis Consortium, 11% of outpatient participants and 35% of hospitalized patients had a cystatin C–based estimated glomerular filtration rate (eGFRcys) that was at least 30% lower than their creatinine-based eGFR (eGFRcr). In the outpatient setting, presence of eGFRcys at least 30% lower than eGFRcr was associated with significantly higher rates of all-cause mortality, cardiovascular events, and kidney failure.
Corresponding Authors: To contact the corresponding authors, email Morgan E. Grams, ...
Disagreement between two kidney function tests predicts serious health problems
2025-11-07
A mismatch between two common tests for kidney function may indicate a higher risk for kidney failure, heart disease, and death, a new study shows.
Health care providers for decades have measured blood levels of the molecule creatinine to track the rate at which kidneys filter waste from muscle breakdown in the bloodstream. According to more recent guidelines, levels of cystatin C, a small protein made by all cells in the body, can also be used to measure kidney function. Since these two tests are influenced by different factors — including some related to disease or aging — using both markers together can provide a better measure of kidney function and risk of organ ...
American College of Cardiology, OpenEvidence to advance AI-enabled, evidence-based cardiovascular care
2025-11-07
The American College of Cardiology (ACC) and OpenEvidence are entering a strategic partnership to accelerate the translation of cardiovascular clinical guidance and research into clinical implementation at the point of care. By combining ACC’s leadership in cardiovascular science and education with OpenEvidence’s advanced generative artificial intelligence (AI) technology, clinicians will have access to the latest relevant and actionable medical evidence to support shared decision-making with their patients.
“At the American College of Cardiology, our mission is to transform ...
OHSU researchers develop promising drug for aggressive breast cancer
2025-11-07
A new molecule developed by researchers at Oregon Health & Science University offers a promising avenue to treat intractable cases of triple-negative breast cancer — a form of cancer that is notoriously aggressive and lacks effective treatments.
In a study published today in the journal Cell Reports Medicine, researchers describe the effect of a molecule known as SU212 to inhibit an enzyme that is critical to cancer progression. The research was conducted in a humanized mouse model.
“It’s an important step forward to treat triple-negative breast cancer,” said senior author Sanjay V. Malhotra, Ph.D., co-director of the Center for Experimental ...
Evaluating the potential of a sleep intervention among youth at high-risk for borderline personality disorder
2025-11-07
Identifying ways that we can optimize Borderline Personality Disorder (BPD) treatment and prevention is an important public health priority. One area for further research is the relationship between sleep and BPD. Disrupted sleep is closely linked to key BPD features, and prior research has found a range of sleep problems among people with BPD. The Brain & Behavior Research Foundation (BBRF) will host a free webinar, “Evaluating the Potential of a Sleep Intervention Among Youth at High-Risk for Borderline Personality Disorder” on Tuesday, November 11, 2025, at 2:00 pm ET. In this webinar, Erin A. Kaufman, Ph.D., Assistant Professor in the Department ...
Saturn’s icy moon may host a stable ocean fit for life, study finds
2025-11-07
New findings from NASA’s Cassini mission show that Enceladus, one of Saturn’s moons and a top contender for extra-terrestrial life, is losing heat from both poles – indicating that it has the long-term stability required for life to develop. The findings have been published today (7 November) in Science Advances.
A new study led by researchers from Oxford University, Southwest Research Institute and the Planetary Science Institute in Tucson, Arizona has provided the first evidence of significant heat flow at Enceladus’ north pole, overturning previous assumptions that heat loss was confined ...
More children, shorter lifespan? Clear evidence from the Great Finnish Famine
2025-11-07
Scientific theory predicts that having more offspring leads to a shorter life span, including in humans. However, despite some hundred years of research, there is no unequivocal evidence for this link. Researchers from the University of Groningen (the Netherlands), the University of Exeter (UK), and the University of Turku (Finland) have now shown that under harsh conditions, the biological cost of reproduction can indeed shorten women’s lifespans. The results were published in Science Advanceson November 7, 2025.
In the 1860s, Finland experienced several harsh winters, resulting in a series of poor harvests and famine. Researcher Euan Young from the ...
Climate intervention techniques could reduce the nutritional value of crops
2025-11-07
A new study in Environmental Research Letters reports that cooling the planet by injecting sulfur dioxide into the stratosphere, a proposed climate intervention technique, could reduce the nutritional value of the world’s crops.
Scientists at Rutgers University used global climate and crop models to estimate how stratospheric aerosol intervention (SAI), one type of solar geoengineering, would impact the protein level of the world’s four major food crops: maize, rice, wheat, and soybeans. The ...
Mapping resilient supply solutions for graphite, a critical mineral powering energy storage: Rice experts’ take
2025-11-07
HOUSTON – (Nov. 7, 2025) – Graphite, the primary anode material in lithium-ion batteries, has become central to energy storage technologies and a growing focus of supply chain concerns. Even as graphite demand is rising faster than lithium demand, global production remains highly concentrated and carbon-intensive.
A perspective article by Rice University researchers traces graphite’s transformation from an industrial commodity to a critical mineral, outlining emerging solutions that could make graphite production ...
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