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Ultrasonication as a tool for directing cell growth and orientation

Ultrasonication as a tool for directing cell growth and orientation
2024-12-05
Developing reliable methods to replace dead or damaged tissue is one of the primary goals of regenerative medicine. With steady advances in tissue engineering and biomedicine, we are almost at a point where growing cell sheets in the lab and transplanting them onto damaged or diseased organs is becoming a reality rather than fiction. Notably, myoblast cell sheets have already been used to successfully treat severe heart failure, demonstrating the potential of this technology. However, there are still a few unsolved challenges ...

Lessons from Earth's hottest epoch in the last 65 million years: How global warming could shrink the tropics' rain belt

Lessons from Earths hottest epoch in the last 65 million years: How global warming could shrink the tropics rain belt
2024-12-05
Earth's tropical rain belt, responsible for monsoons that sustain billions of people and vibrant ecosystems, has long been a reliable feature of the planet's climate. But new research reveals this vital system wasn't always so dependable. A study published in Geophysical Research Letters shows that during the early Eocene—the hottest period in the last 65 million years—the rain belt's seasonal shifts weakened dramatically. These ancient changes could offer critical warnings about the impact of modern global warming. A Greenhouse Climate 50 Million Years ...

Independent rice paddy methane model validated for global applications: Study highlights emission mitigation potential

2024-12-05
Rice paddies, responsible for approximately 10% of global anthropogenic methane (CH₄) emissions, are increasingly recognized as a key contributor to global warming. Reducing emissions from rice cultivation is essential to achieving international climate goals, especially in light of commitments to carbon neutrality and peak emissions targets. A team led by Prof. LI Tingting from the Institute of Atmospheric Physics at the Chinese Academy of Sciences has validated an independently developed methane emission model, CH4MOD, at the global scale. This research highlights the advantages of process-based models over the commonly ...

Infertility linked to onset of systemic autoimmune rheumatic disease after childbirth

Infertility linked to onset of systemic autoimmune rheumatic disease after childbirth
2024-12-05
Women who experience infertility but do not use fertility treatments have a higher risk of developing a group of conditions called systemic autoimmune rheumatic diseases (SARD) in the nine years after a naturally conceived birth compared to women without fertility problems.   The new research, published today (Thursday) in Human Reproduction [1], one of the world’s leading reproductive medicine journals, found that this was true even after accounting for higher rates of pre-eclampsia (high blood pressure during pregnancy), preterm birth ...

Researchers use data from citizen scientists to uncover the mysteries of a blue low-latitude aurora

Researchers use data from citizen scientists to uncover the mysteries of a blue low-latitude aurora
2024-12-05
Colorful auroras appeared around Japan's Honshu and Hokkaido islands on May 11, 2024, sparked by an intense magnetic storm. Usually, auroras observed at low latitudes appear red due to the emission of oxygen atoms. But on this day, a salmon pink aurora was observed throughout the night, while an unusually tall, blue-dominant aurora appeared shortly before midnight.   Smartphone videos and amateur photos captured the event, enabling scientists to combine public data with their own research and study the phenomenon.   In a ...

Possible colon cancer vaccine target uncovered in bacteria

2024-12-05
Higher rates of certain cancers in countries, such as the UK, may be linked to two particular strains of bacteria. Targeting these with treatments or vaccines could help reduce the risk of colorectal, bladder, and prostate cancers. Researchers from the Wellcome Sanger Institute, the University of Helsinki, and collaborators investigated the differences in cancer incidence for colorectal, bladder and prostate cancers, and compared these to global data tracking Escherichia coli (E.coli) strains. Specifically, they looked at the dominant two E.coli strains that produce a substance that has been previously identified as a risk factor for colorectal cancer. Their ...

Eating dark chocolate linked with reduced risk of type 2 diabetes

2024-12-05
Embargoed for release: Wednesday, Dec. 4, 6:30 PM ET Key points: Study participants who consumed at least five servings of any chocolate per week showed a 10% lower risk of type 2 diabetes (T2D) compared to those who rarely or never ate chocolate. Dark chocolate had an even bigger impact: Participants who consumed at least five servings of this chocolate per week showed a 21% lower risk of T2D. Consumption of milk chocolate, but not dark chocolate, was not associated with T2D risk; it was associated ...

Eating dark but not milk chocolate linked to reduced risk of type 2 diabetes

2024-12-05
Eating five servings of dark chocolate a week is associated with a reduction in the risk of type 2 diabetes, according to a long-term US study published by The BMJ today. Global rates of type 2 diabetes are set to rise to 700 million by 2045. Chocolate contains high levels of flavanols (a natural compound found in fruits and vegetables) which have been shown to promote heart health and reduce the risk of type 2 diabetes. But the link between chocolate consumption and risk of type 2 diabetes remains controversial due to inconsistent results. In addition, most previous studies have not looked at whether eating dark and milk chocolate – which have different ...

End food and drink industry’s infiltration of UK children’s education, say experts

2024-12-05
An investigation published by The BMJ today reveals widespread influence of food and drink brands in schools and nurseries – through breakfast clubs, nutrition guidance, and healthy eating campaigns - while rates of obesity in the UK have worsened. Experts say the tactics are “subtle but very problematic” and require much greater scrutiny and pushback. Organisations influencing food provision and education in schools include Kellogg’s, Greggs, Nestle, and the British Nutrition Foundation, a “policy development” charity ...

Concerns over potential harms of tests advertised directly to consumers

2024-12-05
Better information and regulation are essential to protect consumers from potential harms of tests advertised directly to consumers, argue experts in The BMJ today. Emma Gram at the University of Copenhagen and colleagues warn that consumers are at risk of buying products that do more harm than good and say the public needs high quality information and effective communication to protect consumers from unbalanced and misleading marketing. Advances in diagnostic technology and digital health have increased the variety and volume of direct-to-consumer (DTC) tests, ...

War in Lebanon has turned a decade of education crisis into a catastrophe - report

2024-12-05
The recent conflict in Lebanon has deepened a national education crisis in which children have already lost up to 60% of school time over the past six years, new research warns. The report, which will be launched on 5 December by the Centre for Lebanese Studies and the University of Cambridge’s REAL Centre, is the first to assess the state of education since Israel began its ground offensive in Lebanon in October. Using surveys and interviews with parents and teachers, it provides a snapshot of the situation a few weeks before the new ceasefire between Israel and Hezbollah. The study stresses that even ...

Spotted lanternflies in the US are living longer—and cities may be helping them spread

Spotted lanternflies in the US are living longer—and cities may be helping them spread
2024-12-05
Spotted lanternflies—invasive insects that first landed in the United States a decade ago—are emerging earlier and staying active later each year, according to an analysis of citizen-science data by researchers at New York University. This longer life cycle and shift in activity may be driven in part by cities and their warmer climates. The spotted lanternfly, native to parts of Asia, was first found in the US in 2014 in eastern Pennsylvania. Since then, the population has spread across the Northeast and into the Midwest and Southeast, sparking concerns about its impact on local plants and agriculture.  The ...

Slingshot spiders listen to fire off ballistic webs when they hear mosquitoes within range

2024-12-04
Armed with a net and trident, fisherman gladiators were a staple of Rome’s gladiatorial games. Their best chance of survival was to quickly entangle a heavily armed opponent with their weighted net. Remarkably, some spiders use much the same strategy. Slingshot, or ray spiders (Theridiosoma gemmosum) pull the centre of their flat web back, to form a cone with the spider at the tip, keeping the net in place by holding on to a taut anchor thread. They release this thread to let the web fly, catapulting it forward when an ...

SwRI-led study explores risks of chemical exposure from household products

SwRI-led study explores risks of chemical exposure from household products
2024-12-04
SAN ANTONIO — December 4, 2024 — Southwest Research Institute (SwRI) collaborated with the Environmental Protection Agency (EPA) to characterize the chemical makeup of 81 common household items. Researchers also evaluated the potential risk to users. Exposure to chemicals can cause negative health effects, according to the Centers for Disease Control and Prevention. Building on previous research to identify chemicals in consumer goods, SwRI and EPA also analyzed how samples of rubber, plastic, clothing, upholstery and fabric responded to environmental factors, such as a hot car or being worn. The study, published in the Environmental Science & Technology ...

X-ray vision: Seeing through the mystery of an X-ray emissions mechanism

2024-12-04
UNIVERSITY PARK, Pa. — Since the 1960s, scientists who study X-rays, lightning and similar phenomena have observed something curious: In lab experiments replicating these occurrences, electrons accelerated between two electrodes can be of a higher energy than the voltage applied. According to Penn State researchers, this defies an assumption in physics that the energy of the electrons should correspond with the voltage applied. Despite the decades-long awareness of this apparent contradiction, researchers couldn’t ...

AI fact checks can increase belief in false headlines

AI fact checks can increase belief in false headlines
2024-12-04
Although many tech companies and start-ups have touted the potential of automated fact-checking services powered by artificial intelligence to stem the rising tide of online misinformation, a new study led by researchers at Indiana University has found that AI-fact checking can, in some cases, actually increase belief in false headlines whose veracity the AI was unsure about, as well as decrease belief in true headlines mislabeled as false. The work also found that participants given the option to view headlines fact checked by large language model-powered AI were significantly more likely to share both true and false news – but only ...

Poor health outcomes—including early deaths—linger for decades for those who lived in ‘redlined’ neighborhoods

2024-12-04
Redlining—a mid-20th-century federal government practice of denying home loans in African American and other minority neighborhoods—has long been associated with poor health outcomes, including disparate overall mortality rates among racial and ethnic groups. The term gets its name from the practice by the Home Owners’ Loan Corporation (HOLC, operational from 1933 to 1954) of color-coding maps based on each neighborhood’s level of mortgage creditworthiness, with A being the most creditworthy and D—noted with a red line—the least. Now, a new study led by a researcher with the Texas ...

Abnormal prenatal blood test results could indicate hidden maternal cancers

2024-12-04
WHAT: Researchers at the National Institutes of Health (NIH) found previously undetected cancers in 48.6% of pregnant people who had abnormal results for prenatal cell-free DNA (cfDNA) testing used to screen for chromosomal disorders in the fetus. Cancers included colorectal, breast, lung and pancreatic cancers, as well as lymphoma, cholangiocarcinoma and renal carcinoma. The screening test analyzes placental DNA fragments circulating in the maternal bloodstream to identify an extra chromosome or to determine ...

Study finds people on anti-obesity medications cut both weight and alcohol consumption

Study finds people on anti-obesity medications cut both weight and alcohol consumption
2024-12-04
DETROIT (Dec. 04, 2024)—Losing weight with anti-obesity medications (AOM) also resulted in decreased alcohol consumption for about half of the participants in a new study appearing in the current issue of JAMA Network Open. The research, led by Lisa Miller-Matero, PhD, an associate scientist and Associate Director of Health Services Research at Henry Ford Health, adds to a growing body of research that suggests medications such as Ozempic or Wegovy could be adapted to treat substance use disorders. “This was different ...

ETSU secures $900k defense grant

2024-12-04
The U.S. Department of Defense has awarded the ETSU Research Corporation over $900,000 as part of the Defense Industrial Base Consortium, an investment that will help create new opportunities to foster regional innovation in sustainable industrial manufacturing in the Appalachian region. “Our goal is to enhance the prosperity of our region by connecting local innovation with opportunities in global emerging markets,” said Eric Jorgenson, vice president of evelopment for the ETSU Research Corporation. “This project is another key part of the foundation of a robust biomanufacturing ecosystem in ...

ETSU researcher earns grant to build flood dashboard using generative AI

2024-12-04
An East Tennessee State University researcher is developing a cutting-edge dashboard using generative artificial intelligence to assist in monitoring flooding in Central Appalachia.  The pilot project, titled "Leveraging Generative Artificial Intelligence (AI) for Automated Climate Resilience Dashboards: A Case Study on Flood Monitoring in Central Appalachia," has recently secured $20,000 in funding from the Earth Science Information Partners (ESIP) Lab.  Dr. Qian Huang from ETSU’s Center for Rural Health and Research, in collaboration with Dr. ...

AI-enabled analysis of images meant to catch one disease can reveal others

2024-12-04
With the help of an AI tool, computed tomography (CT) scans taken originally to look for tumors or bleeding or infections, also revealed calcium buildup in arteries, a sign of worsening cardiovascular disease.   This is the result of a new study led by researchers at NYU Langone Health and an example of a new trend in “opportunistic screening,” wherein radiologists repurpose existing medical images to diagnose illnesses beyond what the scan was originally designed to find. Presented at the annual Radiological Society of North America ...

Key objections to collecting immigration status data in national health surveys

Key objections to collecting immigration status data in national health surveys
2024-12-04
Nativity—characterized by place of birth, duration of residence in the host country, citizenship and immigration status—greatly influences the health of foreign-born individuals in the United States (U.S.). Despite this, many national health surveys omit questions about these dimensions of nativity, particularly immigration status. This omission limits the ability to assess health disparities across diverse immigrant subgroups and develop evidence-based policies and targeted interventions. To navigate this limitation, researchers rely on proxy measures or imputations ...

Clinical trial of device aims to induce ovulation in women with polycystic ovary syndrome

Clinical trial of device aims to induce ovulation in women with polycystic ovary syndrome
2024-12-04
Physicians at the University of Oklahoma Health Sciences in Oklahoma City are leading a national clinical trial to help women with polycystic ovary syndrome (PCOS)-related infertility who want to become pregnant. The trial, called REBALANCE, studies the safety and effectiveness of an investigational device developed by May Health that is designed to restore ovulation disrupted by PCOS. OU Health reproductive endocrinologist Karl Hansen, M.D., Ph.D., chair of the Department of Obstetrics and Gynecology at the OU College of Medicine, is leading the trial for ...

Natural ‘biopesticide’ against malaria mosquitoes successful in early field tests

2024-12-04
An experimental bacteria-derived biopesticide is highly effective in killing malaria-carrying mosquitoes, including those that have developed resistance to chemical pesticides, according to initial field tests led by researchers at the Johns Hopkins Bloomberg School of Public Health. The biopesticide is a powder made from the dead cells of a common soil-dwelling bacterial species. The researchers showed that the biopesticide efficiently kills both ordinary and chemical-pesticide-resistant mosquitoes when included in standard baits. ...
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