A 16-year Duke Health study of 549 children born with single-ventricle heart disease found that 87% died or developed a major complication, with premature infants facing the steepest odds: over 60% did not survive.

A University of Bristol study found that while most young disposable vape users plan to switch to reusable devices after the UK ban, some dual users and ex-smokers said they might return to cigarettes instead.

Among 58 adults with total or near-total blindness, those who experienced hearing loss early in life reported the lowest confidence in sound localization, and hearing aids did not improve perceived navigational ability.

Women in the rural South are up to 34% more likely to be diagnosed with Stage 4 breast cancer than those in the rural Midwest, and uninsured women face nearly four times the odds of late-stage detection.

Wavelogix, a Purdue University spinout, received a $500,000 NSF Phase IIB grant to scale its Rebel concrete strength sensor, which replaces reactive lab testing with real-time, in-place monitoring on construction sites.

Between 2006 and 2020, the gap between consecutive wildfire smoke events in California shrank by more than 60%, and communities with the least recovery time were disproportionately lower-income and racially diverse.

Workers with intellectual and developmental disabilities using an AR job coaching app reached 93% task accuracy in a single session, a process that typically takes two to four months with a human job coach.

Among Americans with medical debt, 42.3% delayed dental care, 23% delayed medical care, and 14% delayed mental health care -- rates roughly 2 to 4 times higher than those without debt, regardless of insurance status, according to a study of nearly 30,000 adults.

The American Association of Immunologists has appointed Anand Balasubramani, the founding editor of Science Immunology and a veteran of scientific publishing, as its first Chief Scientific Programs Officer to lead strategic expansion of the organization's scientific agenda.

Prior authorization requirements tripled the time to fill ARNI prescriptions and made SGLT2 inhibitor fills take six times longer, with patients facing these barriers more likely to be Black, Hispanic, or insured through Medicaid, a study of 2,183 heart failure patients finds.

A multidisciplinary working group including editors from Nature, JAMA, and PLOS argues that transparency, credit, and accountability should anchor all authorship decisions -- and finds that fewer than half of top U.S. research institutions explicitly link credit to responsibility.

A deep learning model called DDINet, built with just five fully connected layers and molecular fingerprints, accurately predicts drug-drug interactions for entirely unseen drugs -- addressing a critical gap in patient safety for polypharmacy.

By amplifying weak light signals from the brain using interferometry, researchers at NYU Langone Health achieved a 20-fold improvement in signal quality for noninvasive cerebral blood flow monitoring -- using a sensor roughly 100 times cheaper than existing alternatives.

Researchers at SASTRA Deemed University have demonstrated a compact fiber-based method for generating clean ultrashort mid-infrared pulses, compressing 5-picosecond pulses to 187 femtoseconds at just 80 watts of input power -- down from the kilowatt range typically required.

A peptide from a deep-sea sponge near Japan's Yakushima Island simultaneously inhibits ATP synthase and triggers degradation of CD9, a protein linked to cancer recurrence and metastasis -- the first natural product known to degrade this marker.

Even a single course of certain antibiotics is linked to detectable changes in gut microbiome composition four to eight years later, according to a study of 14,979 adults using Sweden's comprehensive drug register and biobank data. Published in Nature Medicine.

In a first-of-its-kind clinical trial, three people with complete spinal cord injuries used dual electrode arrays to simultaneously control leg muscles and receive sensory feedback, allowing them to walk on a treadmill with physical therapist support.

A new technique called magnetoARPES, developed at Rice University, adds a tunable magnetic field to angle-resolved photoemission spectroscopy, allowing researchers to detect collective electron behaviors invisible to conventional methods.

A DNA-based barcoding test developed at Oregon State University can track whether gene therapy nanoparticles reach their target inside cells or get destroyed in lysosomes, enabling the design of far more efficient delivery systems. Published in Nature Biotechnology.

The 2021 North American heat dome killed 92% of Bay mussels and halved caribou detections, but sea lettuce expanded its beach area by 65%. A new study in Nature Ecology and Evolution captures the full ecological scorecard.

Elevated levels of phosphorylated tau protein, widely used as an early blood indicator for Alzheimer's, also occur in transthyretin and immunoglobulin light-chain amyloidosis, conditions that primarily damage the heart and kidneys.

A study of over 80,000 great tits across six decades shows that extreme cold and heavy rain during early development reduce fledging weight and survival, while breeding earlier in the season buffers against the worst effects.

A third of Europeans neither support nor oppose climate policy by default. They decide based on each proposal's personal cost-benefit balance, and shifting even a fraction of them could raise majority-backed climate proposals from 4 out of 15 to 10 out of 15.

A DNA origami-based vaccine called DoriVac produced immune responses comparable to Moderna and Pfizer mRNA vaccines in head-to-head tests, while offering easier storage, simpler manufacturing, and unprecedented control over vaccine composition.

For the first time, researchers have found robust evidence that a black hole and neutron star merged from an oval orbit rather than the expected circular path, suggesting the pair was shaped by dense stellar environments rather than evolving in isolation.