Pausing chikungunya vaccination and accelerated approval
2025-06-05
About The Article: This Viewpoint, by Vinay Prasad, MD, MPH, of the Center for Biologics Evaluation and Research, Food and Drug Administration, and colleagues discusses a safety communication recommending a pause in the use of live attenuated chikungunya virus vaccine.
Corresponding Author: To contact the corresponding author, Vinay Prasad, MD, MPH, email vinayak.prasad@fda.gov.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jama.2025.9393)
Editor’s ...
When the sky takes a midday dip: global patterns in ionospheric bite-outs
2025-06-05
Around midday, Earth’s ionosphere sometimes experiences sharp, short-lived dips in its electron density—an unusual phenomenon known as a noontime bite-out. A new study takes a global view of these midday disruptions, using finely detailed ionospheric maps to compare their behavior in years of high and low solar activity. The research reveals that noontime bite-outs are more widespread and frequent during solar minimum, especially in winter and at higher latitudes. With detailed tracking of timing, intensity, and ...
The National Multiple Sclerosis Society and others announce MS research and training funding opportunities
2025-06-05
As the largest MS organization in the world and a global leader of the MS movement, the National Multiple Sclerosis Society is committed to supporting research and career development that will accelerate breakthroughs in understanding, treating, and ultimately curing MS. The Society is pleased to highlight a number of new funding opportunities aimed to bolster MS research and training. Support originates both from the Society and outside entities.
Awards are summarized below along with individual links to learn more about the details of each award, eligibility, and application instructions.
The National MS Society is offering funding opportunities that invest ...
China successfully develops its first double-spoke superconducting cavity cryomodule
2025-06-05
Designed a high-performance double-spoke superconducting cavity.
The research team implemented comprehensive electromagnetic and mechanical optimizations on the double-spoke superconducting cavity, achieving three key improvements: reduction of peak electric field during normal operation, suppression of multipacting effects, and enhanced manufacturability. A dedicated Buffered Chemical Polishing tooling system was developed for double-spoke superconducting cavities with complex structures, ensuring uniform acid etching and achieving high Q-values (Q > 3.4×10¹⁰ @ Eₐcc = 9 MV/m).
Developed a high-performance cryomodule
The ...
Study helps pinpoint areas where microplastics will accumulate
2025-06-05
The accumulation of microplastics in the environment, and within our bodies, is an increasingly worrisome issue. But predicting where these ubiquitous particles will accumulate, and therefore where remediation efforts should be focused, has been difficult because of the many factors that contribute to their dispersal and deposition.
New research from MIT shows that one key factor in determining where microparticles are likely to build up has to do with the presence of biofilms. These thin, sticky biopolymer layers are shed by microorganisms and can accumulate ...
NRG Oncology study shows the addition of regional nodal irradiation does not decrease rates of invasive breast cancer recurrence in patients whose axillary nodes convert from positive to negative foll
2025-06-05
Recent results from the NRG-NSABP B-51/RTOG 1304 clinical study showed that the addition of regional nodal irradiation (RNI) does not decrease the rates of invasive breast cancer recurrence in patients whose positive axillary nodes at presentation convert to negative following neoadjuvant chemotherapy. These results were recently published in the New England Journal of Medicine.
The study enrolled 1,641 patients stratified by type of surgery (mastectomy, lumpectomy), hormone receptor status (ER-positive and/or PgR-positive; ER- and PgR-negative), HER2 status, adjuvant chemotherapy use, and pathologic complete response (pCR) in the breast, then randomized to RNI vs. ...
Cancer treatments should be licensed for all ages, oncologists say
2025-06-05
Recent advances have resulted in highly effective “tissue-agnostic” drugs that treat cancers based on their molecular markers rather than their tissue of origin, but very few of these drugs are approved for use in children. In an opinion paper publishing June 5 in the Cell Press journal Trends in Cancer, oncologists call for “ag(e)nostic” cancer treatments: drugs that are both tissue agnostic and approved for cancer patients of all ages.
“Cancer treatment in children is a huge unmet need. These drugs are extremely effective, and we want to see children have access to them,” says senior author Razelle ...
US self-reported race and ethnicity are poor proxies of genetic ancestry
2025-06-05
Genetic ancestry is much more complicated than how people report their race and ethnicity. New research, using data from the National Institutes of Health’s (NIH) All of Us Research Program, finds that people who identify as being from the same race or ethnic group can have a wide range of genetic differences. The findings are reported June 5 in the Cell Press journal the American Journal of Human Genetics.
As doctors and researchers learn more about how genetic variants influence the incidence and course of human diseases, the study of genetic ancestry has become increasingly important. This research is driving the field of precision medicine, ...
Living towers of worms observed in nature
2025-06-05
Nematodes are the most abundant animal on earth, but when times get tough, these tiny worms have a hard time moving up and out. So, they play to the strength of their clade. If food runs out and competition turns fierce, they slither towards their numerous kin. They climb onto each other and over one another until their bodies forge a living tower that twists skyward where they might hitch a ride on a passing animal to greener and roomier pastures.
At least that’s what scientists assumed. For decades, these worm structures ...
New AI transforms radiology with speed, accuracy never seen before
2025-06-05
CHICAGO --- A first-of-its-kind generative AI system, developed in-house at Northwestern Medicine, is revolutionizing radiology — boosting productivity, identifying life-threatening conditions in milliseconds and offering a breakthrough solution to the global radiologist shortage, a large new study finds.
The findings will be published on Thursday (June 5) in JAMA Network Open.
“This is, to my knowledge, the first use of AI that demonstrably improves productivity, especially in health care. Even in other fields, I haven’t seen anything close to a 40% boost,” said senior author Dr. Mozziyar Etemadi, an assistant professor of anesthesiology ...
Brain mechanisms that distinguish imagination from reality discovered
2025-06-05
Areas of the brain that help a person differentiate between what is real and what is imaginary have been uncovered in a new study led by UCL researchers.
The research, published in Neuron, found that a region in the brain known as the fusiform gyrus – located behind one’s temples, on the underside of the brain’s temporal lobe – is involved in helping the brain to determine whether what we see is from the external world or generated by our imagination.
The researchers hope that their findings will increase understanding ...
Glucagon-like peptide-1 receptor agonists and risk of neovascular age-related macular degeneration
2025-06-05
About The Study: In this cohort study, the use of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) among patients with diabetes was associated with a 2-fold higher risk of incident neovascular age-related macular degeneration development than among similar patients with diabetes who did not receive a GLP-1 RA. Further research is needed to elucidate the exact pathophysiological mechanisms involved and to understand the trade-offs between the benefits and risks of GLP-1 RAs.
Corresponding Author: To ...
BMI, physical activity, and subsequent neoplasm risk among childhood cancer survivors
2025-06-05
About The Study: Among childhood cancer survivors in this cohort study, obesity was associated with an increased risk for multiple subsequent neoplasm types, while higher physical activity was associated with reduced subsequent neoplasm risk. Lifestyle interventions should be considered in future subsequent neoplasm prevention research.
Corresponding Author: To contact the corresponding author, Lenat Joffe, MD, MS, email ljoffe@northwell.edu.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamaoncol.2025.1340)
Editor’s Note: Please see the article for additional ...
Chimpanzees can catch yawns from androids
2025-06-05
Chimpanzees (Pan troglodytes) can ‘catch’ yawns from an android imitating human facial expressions, according to new research from City St George’s, University of London.
The study, published in Scientific Reports, demonstrates that chimpanzees will both yawn and lie down in response to yawns made by an android, suggesting that it may act as a cue to rest rather than simply triggering an automatic response.
The findings appear to show contagious yawning due to an inanimate model for the first time, according to the authors, and the study also ...
The Holberg Prize conferred upon Professor Gayatri Chakravorty Spivak
2025-06-05
At a prestigious award ceremony today in the University Aula in Bergen, Gayatri Chakravorty Spivak received the international research award from HRH Crown Prince Haakon of Norway. Spivak is University Professor in the Humanities at Columbia University.
The Holberg Prize is worth NOK 6 million (approx. USD 600,000) and is awarded annually for outstanding contributions to research in the humanities, social sciences, law or theology.
Expressing her deepest gratitude as well as her surprise on receiving the award, Spivak accepted the Holberg ...
Up and running—first room-temperature quantum accelerator of its kind in Europe
2025-06-05
To further accelerate its pioneering research in the field of quantum computing, the Fraunhofer Institute for Applied Solid State Physics IAF is expanding its unique quantum computing infrastructure with the latest system from Quantum Brilliance (QB).
Following a public tender, the Quantum Development Kit (QB-QDK2.0) is operational and integrated directly into the high-performance computing infrastructure at Fraunhofer IAF. The system requires no cryogenics, fits into a standard 19” server rack, and enables energy-efficient, hybrid quantum-classical computing in conventional IT environments. ...
Using swarm intelligence to improve treatment of acute stroke
2025-06-05
Researchers at DZNE and the Department of Vascular Neurology at the University Hospital Bonn (UKB) aim to develop a computer model based on artificial intelligence (AI) to aid doctors in treating stroke patients. Serving as a digital assistance system, it is intended to predict the long-term outcome of patients after a minimally invasive treatment (mechanical thrombectomy) and potential complications, thereby helping doctors decide on the best possible therapy. A proof-of-concept study will now be undertaken to determine whether this is feasible using data from the “German Stroke Registry” and additional brain images. The project relies on an AI technology called “Swarm ...
Weight stigma—not BMI—has the biggest effect on mental health after weight-loss surgery
2025-06-05
New research shows that weight stigma—and not weight itself—has the biggest impact on mental health and healthy behaviors in the years after weight-loss surgery.
Researchers found that patients who had gone through weight-loss surgery tended to experience much less weight stigma, and that this reduction in weight stigma—but not lower BMI—was associated with healthier eating habits and better mental health. On the other hand, continuing to experience stigma after surgery was associated with higher risks of ...
Research alert: Alzheimer's gene therapy shows promise in preserving cognitive function
2025-06-05
Researchers at University of California San Diego School of Medicine have developed a gene therapy for Alzheimer’s disease that could help protect the brain from damage and preserve cognitive function. Unlike existing treatments for Alzheimer’s that target unhealthy protein deposits in the brain, the new approach could help address the root cause of Alzheimer’s disease by influencing the behavior of brain cells themselves.
Alzheimer's disease affects millions of people around the world and occurs when abnormal ...
New York Eye and Ear Infirmary of Mount Sinai opens first Comprehensive Center for Refractive Solutions in New York
2025-06-05
New York Eye and Ear Infirmary of Mount Sinai (NYEE) has announced the opening of the Center for Refractive Solutions—the first in New York City and one of few in the United States—that offers comprehensive and innovative treatment options for those who require refractive correction. This includes premium cataract and intraocular lens surgery, and corneal refractive procedures such as LASIK, to reduce patients’ dependency on glasses and contact lenses.
The newly renovated space, located at 310 East 14th Street in Lower Manhattan, is solely dedicated ...
Storm ready: FAU Sensing Institute’s weather network delivers real-time forecasting
2025-06-05
As Floridians prepare for an active 2025 Atlantic hurricane season, the most serious threat may not come from wind, but from water. Data from the National Hurricane Center shows that 86% of all direct hurricane and tropical storm fatalities in the United States between 2013 and 2023 were caused by water impacts – freshwater flooding, storm surge and rip currents. Of those, more than half resulted from drownings due to inland flooding, highlighting the critical importance of accurate rainfall and flood forecasting.
Florida Atlantic University’s Sensing Institute (I-SENSE) has emerged as a vital contributor to the nation’s ...
UChicago receives $21 million to establish visionary center in quantum engineering and health
2025-06-05
A $21 million gift from philanthropist Thea Berggren to the University of Chicago will establish the Berggren Center for Quantum Biology and Medicine, launching a bold scientific field that merges quantum technology with biology to transform the future of medicine.
This pioneering, interdisciplinary effort seeks to harness the power of quantum engineering — capable of the most sensitive measurements known to science — to peer inside the human body in unprecedented ways. The goal is to unlock insights into biology and disease that were previously out of reach, ...
Inherited genetic trait predicts resistance to immunotherapy for deadly skin cancer
2025-06-05
Tests in 1,225 patients with the most deadly form of skin cancer reveal for the first time a genetic trait among most of those who did not respond to the latest cancer treatments, known as immune checkpoint inhibitors. Metastatic melanoma, as the disease is formally named, kills nearly 10,000 Americans annually.
While the drugs have proven highly successful in treating metastatic melanoma and several other cancers, the therapies are known to not work for almost half of those who are prescribed them, usually after initial chemotherapy or surgery have failed ...
Oxford physicists recreate extreme quantum vacuum effects
2025-06-05
Physicists at the University of Oxford have successfully simulated how light interacts with empty space—a phenomenon once thought to belong purely to the realm of science fiction.
The simulations recreated a bizarre phenomenon predicted by quantum physics, where light appears to be generated from darkness.
The findings pave the way for real-world laser facilities to experimentally confirm bizarre quantum phenomena.
The results have been published today (5 June) in Communications Physics.
Using advanced computational modelling, a research team led by the University of Oxford, working in partnership with the Instituto Superior Técnico in the University of Lisbon, ...
Talking therapy could be effective treatment for stroke survivors
2025-06-05
Stroke survivors with depression or anxiety who attend talking therapy sessions are more likely to recover from their psychological symptoms, finds a new study by UCL researchers.
The first of its kind study, published in Nature Mental Health, analysed data from all 1.9 million patients who attended NHS Talking Therapies for Anxiety and Depression services in England between 2012 and 2019, including 7,597 stroke survivors.
More than one in three stroke survivors experience depression or anxiety. Without appropriate mental health treatment, ...
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