A new study explores how epigenetic markers—chemical modifications that influence gene activity—can help predict the risk of developing cardiometabolic diseases and guide personalized prevention strategies. The findings are particularly significant as the prevalence of major cardiometabolic risk factors such as hypertension, diabetes, and obesity continues to rise despite advancements in healthcare and treatment. This trend highlights the need for better early detection and intervention. The study is titled “Poly-epigenetic scores for cardiometabolic risk factors interact with demographic factors and health behaviors in older US Adults” and is published in the journal ...

The BBVA Foundation Frontiers of Knowledge Award in Basic Sciences has gone in this seventeenth edition to Avelino Corma (Institute of Chemical Technology, Universitat Politècnica de València-CSIC, Spain), John F. Hartwig (University of California, Berkeley, United States) and Helmut Schwarz (Technical University of Berlin, Germany) for fundamental advances in the catalysis field, in the words of the committee, that have made it possible to “control and accelerate chemical ...

For human health, prematurely aging cells are a big problem. When a cell ages and stops growing, its function changes, which can cause or worsen cardiovascular disease, Alzheimer’s disease and other chronic diseases. But these cells are also like needles in a haystack, difficult to identify by traditional scientific measures.  To find these problematic cells, a University of Illinois Chicago doctoral student has developed a powerful new software platform called SenePy. In a paper for Nature Communications, Mark ...

Inventors from The University of Texas at Arlington have once again been a vital part of the University of Texas System’s recognition as one of the world’s leading innovation centers. According to the prestigious National Academy of Inventors (NAI), UT System ranks No. 6 on its Top 100 Worldwide Universities Granted U.S. Utility Patents list for 2024. UTA contributed 23 patents—an increase of 15% over 2023—to UT System’s total of 234 last year. “Being a top-ranking member of the Top 100 Worldwide ...

Mesoscale eddies, oceanic swirling currents with typical horizontal scales of 10-100 kilometres in diameter, are ubiquitous features of the global ocean and play a vital role in marine ecosystems. Eddies, which form in biologically productive coastal upwelling regions, are important vehicles for the transport of carbon and nutrients. These eddies trap water masses and migrate into the open ocean, where productivity is comparatively low. As such, they have a significant influence on the nutrient and carbon cycles within the ocean.  For decades, marine scientists have sought to understand in detail how coastal waters are transported offshore and how this process affects productivity in ...

Ever since 1993, when a deadly disease outbreak in the Four Corners first revealed the presence of hantavirus in North America, New Mexicans have been warned to be on the lookout for deer mice, which harbor the microbe and can spread it through their droppings. A few human cases, usually presenting with severe cardiopulmonary symptoms, typically occur in New Mexico each year – almost all in the northwestern quadrant of the state – and even with advanced treatment about 35 percent of patients die. But now, University of New Mexico researchers have found ...

A recent study conducted by Nora Medina, PhD, a postdoctoral researcher of family and community medicine at Thomas Jefferson University, along with colleagues from the University of Chicago, highlights the importance of the emotional bond that a mother establishes with her child during pregnancy. The study team followed 160 young, low-income, racially diverse mothers from pregnancy until their children were two and a half years old. Mothers who felt more connected to their babies during pregnancy were more likely to have a healthier, positive relationship with their children ...

When skin is cut or damaged, tiny cell fragments circulating in the blood, called platelets, arrive at the injury and spread out to stop the blood from leaking out. Once enough layers of platelets accumulate, like stacks of sandbags against a flood, a blood clot is formed, trapping red blood cells. When the break occurs in a blood vessel, the clot contracts to facilitate smooth blood flow through the vessels. Until recently, researchers believed that platelet spreading and clot contraction were controlled ...

From virtual reality to rehabilitation and communication, haptic technology has revolutionized the way humans interact with the digital world. While early haptic devices focused on single-sensory cues like vibration-based notifications, modern advancements have paved the way for multisensory haptic devices that integrate various forms of touch-based feedback, including vibration, skin stretch, pressure and temperature. Recently, a team of experts, including Rice University’s Marcia O’Malley and Daniel ...

Prostate cancer is the second-leading cause of cancer deaths in American men. Further, non-Hispanic Blacks have a higher incidence of prostate cancer and are more likely to die from it than are non-Hispanic whites. A biopsy is recommended if a patient has certain risk factors like age, family history, symptoms and screening test results. When the biopsy sample is taken, physicians use either ultrasound or magnetic resonance imaging (MRI) to guide the procedure. In a new study, researchers at Thomas Jefferson ...

Academic peer review is notoriously cumbersome. The process assesses the quality of scientific research prior to publication in an academic journal, sometimes delaying publication by many months. The system depends on members of the academic community providing their time and expertise for free. However, finding reviewers can be lengthy and there are no consequences when reviewers produce poor-quality reports lacking constructive feedback. Daniel Gorelick, Editor-in-Chief of the journal Biology Open believed that there could an alternative. ‘My vision is a ...

Frogs have thrived for hundreds of millions of years, spreading across virtually every corner of the earth, from tropical jungles to subarctic forests. Throughout their evolution, they have developed remarkable defenses — including previously unreported antibiotics — against the hordes of bacteria that thrive in their moist environments. Variants of these compounds may one day protect humans from drug-resistant pathogens. In a new paper in Trends in Biotechnology (Cell Press), Cesar de la Fuente, Presidential Associate Professor in Bioengineering and in Chemical and Biomolecular ...

WASHINGTON, March 25, 2025 — Foie gras is a unique delicacy made from the liver of a duck or goose. While it can be an acquired taste, the buttery, fatty dish is an indulgent cuisine prized in many parts of the world. Foie gras is distinct from regular fowl liver thanks to its high fat content, which is traditionally achieved by force-feeding the ducks and geese beyond their normal diets. Researcher Thomas Vilgis is a lover of foie gras, but he wondered if there was a more ethical way to enjoy the dish. In Physics of Fluids, by AIP Publishing, Vilgis, as well as researchers from Max Planck Institute for Polymer Research and the University of Southern Denmark, created a process to ...

WASHINGTON, March 25, 2025 – Butter is a key ingredient in many baked goods, but for those who are lactose intolerant, finding a good alternative can be a challenge. Vegan butters can sometimes have the wrong consistency, or produce bakes that are not quite right, leaving bakers frustrated or unwilling to try dairy-free alternatives. In Physics of Fluids, by AIP Publishing, researchers from the University of Strathclyde examined the properties of several vegan or dairy-free butter alternatives inside one of the region’s most well-known snacks: Scottish shortbread. “We have a Ph.D. student in the group who is a vegan, and he turns all of our baking habits upside down,” ...

About The Study: In this cohort study of comatose patients resuscitated from cardiac arrest, most who died after withdrawal of life-sustaining therapy were considered by experts to have had recovery potential. These findings suggest that novel solutions to avoiding deaths based on biased prognostication or incomplete information are needed. Corresponding Author: To contact the corresponding author, Jonathan Elmer, MD, MS, email elmerjp@upmc.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2025.1714) Editor’s Note: Please ...

About The Study: Nurses in hospitals with high lesbian, gay, bisexual, transgender, queer or questioning, and other sexual and gender minority (LGBTQ+) inclusion reported more favorable job outcomes and care quality in this cross-sectional study. Hospitals should understand that implementing LGBTQ+ inclusive policies goes beyond compliance or diversity; it is essential for improving the work climate, enhancing staff well-being, and optimizing care delivery. Corresponding Author: To contact the corresponding author, Hyunmin Yu, PhD, email hyuy@nursing.upenn.edu. To access the embargoed study: Visit our For The Media ...

The pathogen C. diff — the most common cause of health care-associated infectious diarrhea — can use a compound that kills the human gut’s resident microbes to survive and grow, giving it a competitive advantage in the infected gut.  A team led by investigators at Vanderbilt University Medical Center has discovered how C. diff (Clostridioides difficile) converts the poisonous compound 4-thiouracil, which could come from foods like broccoli, into a usable nutrient. Their findings, published March 25 in the journal Cell Host & Microbe, increase ...

DALLAS, March 25, 2025 — Understanding how to properly respond in a cardiac emergency when seconds matter is critical to everyone, everywhere. That is why the American Heart Association, devoted to changing the future to a world of healthier lives for all, and its Nation of Lifesavers™ national ambassador and Buffalo Bills safety, Damar Hamlin, are expanding the Chasing M’s Foundation cardiopulmonary resuscitation (CPR) tour to Tokyo during March 27-30. This work is supporting the American Heart Association’s impact goal to improve survival rates of out-of-hospital cardiac arrest[1]. “Our national Nation ...

New research led by American Cancer Society (ACS) researchers estimates more than 3.8 million lung cancer deaths were averted and a little over 76 million years of life gained in the United States during 1970-2022 due to substantial reductions in smoking prevalence driven by tobacco control. The study is published today in CA: A Cancer Journal for Clinicians. “The substantial estimated numbers of averted lung cancer deaths and person-years of life gained highlight the remarkable effect of progress ...

Background and Aims Cholesterol synthesis and gallstone formation are promoted by trimethylamine-N-oxide (TMAO), a derivative of trimethylamine, which is a metabolite of gut microbiota. However, the underlying mechanisms of TMAO-induced lithogenesis remain incompletely understood. This study aimed to explore the specific molecular mechanisms through which TMAO promotes gallstone formation. Methods Enzyme-linked immunosorbent assays were used to compare serum concentrations of TMAO, apolipoprotein A4 (APOA4), and ...

When the plasma inside a fusion system starts to misbehave, it needs to be quickly cooled to prevent damage to the device. Researchers at Commonwealth Fusion Systems believe the best bet is a massive gas injection: essentially, a well-timed, rapid blast of cooling gas inside their fusion system, which is known as SPARC. But how many gas valves does it take to quickly tame a plasma that is hotter than the sun? The team has to strike the perfect balance: with too few valves, some parts of SPARC might overheat. With too many, valuable space inside the ...

About 4.5 million workers in the United States quit their jobs in 2022, continuing a trend that began after the 2007 Great Recession. Despite better labor conditions and the pandemic’s decline, many adults are still less willing to return to work compared to previous recessions, making it harder for companies to attract and retain top talent. Moreover, voluntary turnover – when an employee quits their job as opposed to being fired or laid off – costs U.S. businesses more than $1 trillion each year. Beyond recruitment and training expenses, turnover disrupts operations, damages customer relationships, and often leads to further departures. Replacing an employee ...

LOS ANGELES — City of Hope®, one of the largest and most advanced cancer research and treatment organizations in the U.S. with its National Medical Center named top 5 in the nation for cancer by U.S. News & World Report, has opened a phase 1 trial seeking to one day transform rectal cancer from a mostly radiation-resistant disease to one that can be cured using radiation and chemotherapy. “Many cancers are cured through radiation therapy alone or radiation in combination with chemotherapy, including — but not limited to — prostate, head and ...

The rate of maternal mortality related to cardiovascular causes more than doubled between 1999 and 2022 in the United States, according to a study being presented at the American College of Cardiology’s Annual Scientific Session (ACC.25). The finding is concerning, especially as the U.S. has the highest overall rate of maternal mortality among all developed countries, researchers said. Since cardiovascular problems are a leading cause of death around the time of pregnancy and childbirth, the new findings shed light on the drivers behind recent trends and draw attention to particularly high rates of mortality seen among ...

Tiny fragments of plastic have become ubiquitous in our environment and our bodies. Higher exposure to these microplastics, which can be inadvertently consumed or inhaled, is associated with a heightened prevalence of chronic noncommunicable diseases, according to new research being presented at the American College of Cardiology’s Annual Scientific Session (ACC.25). Researchers said the new findings add to a small but growing body of evidence that microplastic pollution represents an emerging health threat. In terms of its relationship with stroke risk, for example, microplastics concentration ...