The American Geriatrics Society (AGS) has released a landmark update to its list of alternatives to medications listed in the 2023 AGS Beers Criteria® — the most widely adopted guidelines to help clinicians identify potentially inappropriate medications for older adults. This new effort delivers not only a comprehensive suite of safer pharmacologic options, but also a strong emphasis on effective non-pharmacologic treatments for common conditions impacting frail and aging populations. The AGS panel is comprised of 19 national experts from 14 states, ...

When health secretary Robert F. Kennedy Jr. recently fired an entire federal vaccine advisory panel, he described the unprecedented move as necessary to rid the committee of industry influence. However, new research from the USC Schaeffer Center for Health Policy & Economics finds that reported conflicts on that Centers for Disease Control and Prevention panel had been at historic lows for years before Kennedy’s abrupt dismissal. Furthermore, the type of conflict typically considered the most concerning—income ...

About The Study: Among patients with severe chronic rhinosinusitis with nasal polyps treated with a daily intranasal corticosteroid, stapokibart, a novel monoclonal antibody, reduced polyp size and severity of nasal symptoms at 24 weeks. Corresponding Authors: To contact the corresponding authors, email Luo Zhang, MD, (dr.luozhang@139.com) and Chengshuo Wang, MD, (wangcs830@126.com). To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jama.2025.12515) Editor’s Note: Please see the article for additional information, including other authors, author contributions ...

A new study reports evidence of a link between prenatal exposure to the widely used insecticide chlorpyrifos (CPF) and structural abnormalities in the brain and poorer motor function in New York City children and adolescents. The findings are the first to demonstrate enduring and widespread molecular, cellular, and metabolic effects in the brain, as well as poorer fine motor control among youth with prenatal exposure to the insecticide. The study by researchers at Columbia University Mailman School of Public Health, Children’s ...

About The Study: Study participants with hearing loss with hearing aids showed reduced risk for dementia among those younger than age 70 at the time of hearing evaluation, when followed up for up to 20 years. This finding highlights the importance of early intervention for hearing loss for possible prevention of dementia. Corresponding Author: To contact the corresponding author, Sudha Seshadri, M.D., email seshadri@uthscsa.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi: 10.1001/jamaneurol.2025.2713) Editor’s Note: Please see the article for additional information, including ...

About The Study: In this cross-sectional study of U.S. individuals obtaining oral contraception, the oral contraceptive pill was accessed over-the-counter (OTC) by many who previously used no method or less-effective contraception. These findings suggest that OTC access may improve equitable access to contraception. Corresponding Author: To contact the corresponding author, Maria I. Rodriguez, M.D., M.P.H., email rodrigma@ohsu.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi: 10.1001/jamanetworkopen.2025.27438) Editor’s Note: Please see the article for additional ...

Two years ago, the Food and Drug Administration approved the sale of an over-the-counter birth control pill for the first time in the United States without a prescription. A nationwide study published today reveals the decision has dramatically improved access to contraception, especially among women who otherwise would have had no birth control at all, either because they lack insurance or routine access to health care. The study was conducted by researchers at Oregon Health & Science University. Published in the journal ...

Researchers have identified key factors that influence the flavour of chocolate during the cocoa bean fermentation process, a discovery that could offer chocolate producers a powerful tool to craft consistently high-quality, flavour-rich chocolate. Scientists from the University of Nottingham’s School of Biosciences examined how cacao bean temperature, pH, and microbial communities interact during fermentation and how these factors shape chocolate flavour. The team identified key microbial species and metabolic traits associated with fine-flavour chocolate and found that both abiotic factors (such as temperature and ...

SAN ANTONIO — August 18, 2025 — A Southwest Research Institute (SwRI) review of data collected from near-Earth asteroids Bennu and Ryugu supports the hypothesis that they were originally part of the Polana collisional family in the main asteroid belt between the orbits of Mars and Jupiter. The study compared spectroscopy data from Polana with spacecraft and laboratory data from Bennu and Ryugu samples, discovering similarities in their near-infrared spectrum sufficient to support the theory that they originate ...

On Japan’s desert islands, researchers uncovered a peculiar bathroom ritual among seabirds. Reporting in the Cell Press journal Current Biology on August 18, the team found that streaked shearwaters (Calonectris leucomelas) poop while flying—not while floating on water—and they do so every 4 to 10 minutes. This habit may help the birds stay clean and fertilize the ocean below.  But the team didn’t set out to document the seabirds’ bathroom habits. “I was studying how seabirds run on sea surface to take off,” says Leo Uesaka, the lead author from the University ...

SAN ANTONIO — August 18, 2025 — Southwest Research Institute (SwRI) has developed and tested a micrometeoroid and orbital debris (MMOD) detection and characterization system designed for satellites and spacecraft to monitor impacts from space debris. The system provides critical post-impact data, ensuring awareness of an impact even when damage is not immediately apparent. Space debris around Earth is a growing problem, a result of commercial satellites exploding, anti-satellite missile tests and accidents that contribute to a growing junk field. Depending ...

To the point Exploratory behavior: Grackles who were trained to be more flexible were more exploratory after the training than untrained grackles. This indicates that the more an individual investigates a novel object, the more it can learn and adapt its behavior accordingly. Range expansion: Grackles in an edge population disperse farther than those in a more central population. This suggests that the rapid geographic range expansion of great-tailed grackles is associated with individuals differentially expressing dispersal behaviors. Key traits: Flexibility, exploration, and dispersal are key ...

Flowers, specialized plant structures consisting of colorful petals and green sepals, play a key role in plant propagation. In addition to their ornamental value, flowers have gained emotional and cultural significance over the years. African violet, scientifically known as Streptocarpus sect. Saintpaulia ionanthus Wendl., is a remarkable ornamental plant with unique color patterns in its flowers owing to the accumulation of anthocyanins—a chemical substance that imparts different colors. Among the diverse varieties of Saintpaulia flowers, the white-striped petal variety has been exclusively bred for their aesthetic appeal and horticultural value. Until recently, scientists ...

Metal oxide materials with nanoscale pores have been applied and studied in a wide range of fields, including as catalysts, adsorption and separation materials, and energy materials. Among them, single-crystalline nanoporous metal oxides—with interconnected nanopores in a single crystal—are especially lucrative. They have recently attracted attention as unique materials that combine the desirable properties of nanoporous materials, such as high specific surface area and large pore volume, with those of single crystals. While metal oxide nanoporous structures have been conventionally synthesized by replicating the nanostructure ...

A team of scientists at the Garvan Institute of Medical Research has discovered that inactivation of a stress pathway makes ER+ breast cancer cells ignore stress signals, allowing them to evade treatment. A study led by researchers at the Garvan Institute of Medical Research has uncovered why some breast cancers become resistant to treatment, potentially opening the door to more effective therapies for patients. Published today in the Journal of Experimental & Clinical Cancer Research, the study reveals how disruption to a cellular stress response system involving the JNK pathway allows estrogen receptor-positive (ER+) breast cancer cells to evade ...

FORT COLLINS, Colo. — The Physicians Committee for Responsible Medicine, a nonprofit national medical ethics group, applauds Colorado State University for its decision to shutter a nutrition study for which the university had approved the killing of 17,766 animals. The study, funded by the U.S. Department of Agriculture and the university, claimed to investigate the effect of legumes on the human gut microbiome. Public records reveal the primary investigator had to date used 1,587 mice. An initial USDA grant of $498,500 funded the experiments. A subsequent USDA Cooperative Agreement, active through ...

WASHINGTON, Aug. 18, 2025 — Heat waves are becoming more common, severe and long-lasting. These prolonged periods of hot weather are especially dangerous in already hot places like Texas. In 2023, more than 300 people in Texas died from heat, according to the Texas Department of State Health Services, the most since the state began tracking such deaths in 1989. Researchers found it may not only be temperatures that make heat waves unsafe but also the heat-related increase in airborne pollutants.  Bianca Pamela Aridjis-Olivos, a graduate student in aerosol and atmospheric chemistry at Texas A&M University will present her team’s results at the fall meeting of ...

WASHINGTON, Aug. 18, 2025 — More than half of the 7.5 million bales of cotton produced annually in the U.S. will be used in clothing manufacturing. The finishing techniques used to make cotton fabric smooth, water-repellant and resistant to wrinkling can be detrimental to the environment and the wearer. Now, researchers propose a method for using cottonseed oil as a “greener” and safer alternative to formaldehyde and per- and polyfluoroalkyl substances (PFAS), often called forever chemicals, ...

WASHINGTON, Aug. 18, 2025 — Acetaminophen is one of the most common painkillers and is found in hundreds of different medications. While safe at recommended doses, acetaminophen overdose is the leading cause of acute liver injury in the U.S. Now, researchers propose that a new molecule has the potential to treat acetaminophen-induced liver injury (AILI) and other inflammatory conditions. They conducted a small-scale mouse trial and found that the new compound decreased AILI-caused liver inflammation and prevented liver damage. Jannatun Nayem Namme, a graduate ...

WASHINGTON, Aug. 18, 2025 — From electric cars to artificial intelligence (AI) data centers, the technologies people use every day require a growing need for electricity. In theory, nuclear fusion — a process that fuses atoms together, releasing heat to turn generators — could provide vast energy supplies with minimal emissions. But nuclear fusion is an expensive prospect because one of its main fuels is a rare version of hydrogen called tritium. Now, researchers are developing new systems to use nuclear waste ...

A new study published today in Nature Food evaluates the impacts of the European Chicken Commitment (ECC), an initiative calling on food companies to adopt slower-growing breeds and higher welfare standards. While concerns over increased costs and emissions have been barriers to adoption, the study puts those concerns in perspective. For example, using EU carbon externality costs (the cost for companies to emit one tonne of CO₂ under the EU Emissions Trading System), the study showed that it costs less than one-hundredth of a cent to prevent each hour of intense pain —equivalent to the emissions from ...

WASHINGTON, Aug. 18, 2025 — Millions of Americans have altered vision, ranging from blurriness to blindness. But not everyone wants to wear prescription glasses or contact lenses. Accordingly, hundreds of thousands of people undergo corrective eye surgery each year, including LASIK — a laser-assisted surgery that reshapes the cornea and corrects vision. The procedure can result in negative side effects, prompting researchers to take the laser out of LASIK by remodeling the cornea, rather than cutting it, in initial animal tissue tests. Michael Hill, a professor ...

The trouble with many drugs is that they go where they shouldn’t, producing unwanted side effects. Psychiatric drugs might cause dissociation, painkillers can induce nausea and chemotherapy often damages healthy cells. Now a team of Stanford Medicine researchers are closing in on a novel solution: a non-invasive system that can deliver drugs anywhere in the body with precision down to a few millimeters. The system uses nanoparticles to encapsulate drugs along with ultrasound to unleash the drugs at their intended destinations.  In a new study, published Aug. 18 ...

The body’s cells change their shape to close gaps such as wounds – with part of the cell flexing depending on the curve of the gap and the organisation of cell-internal structures, a new study reveals. Epithelial cells line the body’s surfaces inside and out - forming a barrier to protect against physical damage, pathogens, and dehydration. They play key roles in absorbing nutrients and removing waste products, as well as producing substances such as enzymes and hormones. Scientists have discovered that these cells’ endoplasmic reticulum (ER) ...

High frequency radio waves can wirelessly carry the vast amount of data demanded by emerging technology like virtual reality, but as engineers push into the upper reaches of the radio spectrum, they are hitting walls. Literally. Ultrahigh frequency bandwidths are easily blocked by objects, so users can lose transmissions walking between rooms or even passing a bookcase. Now, researchers at Princeton engineering have developed a machine-learning system that could allow ultrahigh frequency transmissions to dodge those obstacles. In an August 18 article in Nature Communications, the researchers unveiled a system ...