Trends in medical and nonmedical use of prescription stimulants among US adolescents

JAMA

2025-07-29

(Press-News.org) About The Study: Among U.S. adolescents, current medical use of prescription stimulants for attention-deficit/hyperactivity disorder (ADHD) increased between 2005 and 2023, while nonmedical use decreased. Lifetime nonmedical use was more prevalent than medical use in early cohorts but shifted to being less prevalent in recent cohorts. These findings are consistent with declines in peer-to-peer diversion among adolescents following COVID-related school closures and findings from adult studies.

Corresponding Author: To contact the corresponding author, Sean Esteban McCabe, PhD, email plius@umich.edu.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jama.2025.11260)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

# # #

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2025.11260?guestAccessKey=87ddd01c-0025-4ed0-b942-f77db5009ac8&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=072925

END

ELSE PRESS RELEASES FROM THIS DATE:

Trapping gut bacteria’s hidden fuel improves blood sugar and liver health, study shows

2025-07-29

A team of Canadian scientists has discovered a surprising new way to improve blood sugar levels and reduce liver damage: by trapping a little-known fuel made by gut bacteria before they wreak havoc on the body. The findings, published in Cell Metabolism on July 29, 2025, could open the door to new therapies to treat metabolic diseases like type 2 diabetes and fatty liver disease. Researchers at McMaster University, Université Laval and the University of Ottawa showed that a molecule produced by microbes in ...

Uncovering how a molecule responsible for immune “brakes” directs skin defenses

2025-07-29

Weill Cornell Medicine researchers have discovered that PD-1—a molecule best known for putting the brakes on immune cells—also plays a critical role in helping T cells become long-term immune defenders in the skin. Early during infection, PD-1 acts like a steering wheel, guiding T cells to become protective resident memory T cells (TRM) that stay in place. These cells remember invading germs or cancer and quickly mount a response if that enemy reappears. The preclinical findings, published July 29 ...

miRNA dysregulation of AGE/RAGE pathway in metabolic syndrome: a novel analysis strategy utilizing miRNA-profiling data

2025-07-29

Metabolic Syndrome (MetS), characterized by abdominal obesity, hypertension, dyslipidemia, and insulin resistance, represents a global health crisis with escalating prevalence. Its comorbidities—including type 2 diabetes mellitus (T2DM), non-alcoholic fatty liver disease (NAFLD), atherosclerosis, and polycystic ovary syndrome (PCOS)—share underlying molecular pathways. Among these, the receptor for advanced glycation end products (RAGE) and its ligands (AGEs, HMGB1, S100 proteins) form the AGE/RAGE axis, a key driver of inflammation, oxidative stress, and tissue damage in MetS. While targeting this axis is a promising therapeutic strategy, ...

AI catches one-third of interval breast cancers missed at screening

2025-07-29

OAK BROOK, Ill. – An AI algorithm for breast cancer screening has potential to enhance the performance of digital breast tomosynthesis (DBT), reducing interval cancers by up to one-third, according to a study published today in Radiology, a journal of the Radiological Society of North America (RSNA). Interval breast cancers—symptomatic cancers diagnosed within a period between regular screening mammography exams—tend to have poorer outcomes due to their more aggressive biology and rapid growth. DBT, or 3D mammography, can improve visualization of breast lesions and reveal cancers that may be obscured by dense tissue. Because DBT is ...

Researchers advocate for separate roles between AI and humans

2025-07-29

OAK BROOK, Ill. – Renowned physician-scientist Eric J. Topol, M.D., and Harvard artificial intelligence (AI) expert Pranav Rajpurkar, Ph.D., advocate for a clear separation of the roles between AI systems and radiologists in an editorial published today in Radiology, a journal of the Radiological Society of North America (RSNA). “We’re stuck between distrust and dependence, and missing out on the full potential of AI,” said Dr. Rajpurkar, associate professor of Biomedical Informatics at Harvard University. The ...

SwRI expands antenna testing capabilities with spherical near-field range

2025-07-29

SAN ANTONIO — July 29, 2025 — Southwest Research Institute (SwRI) is expanding its antenna measurement capabilities with a state-of-the-art spherical near-field antenna range. The 1,260-square-foot indoor range, lined with radio frequency and microwave foam absorbers, is equipped to accurately sample the near field of an antenna. Near-field measurements can be mathematically transformed into far-field data. “Near field” refers to the complex electromagnetic fields close to the antenna, while the “far field” encompasses the predictable ...

The complex relationship between fusion fuel and lithium walls

2025-07-29

Lithium is considered a key ingredient in the future commercial fusion power plants known as tokamaks, and there are several ways to use this metal to enhance the process. But a key question remained: How much does it impact the amount of fuel trapped in the walls of tokamaks? According to new research from a global collaboration spanning nine institutions, the dominant driver of fuel retention is co-deposition: a process where fuel is trapped alongside lithium. Co-deposition can happen with lithium that is directly added during plasma operations, ...

Study refutes blood thinner brain bleed risk after falls in older adults

2025-07-29

There are about 70 million baby boomers in the United States, many now over age 65. As people age, rates of cardiovascular and cerebrovascular diseases rise, leading to more use of blood thinners such as warfarin. At the same time, older adults face a higher risk of head injuries and brain bleeding, especially after falls. Falls are the leading cause of injury and death in older adults, causing 38,000 deaths and 3 million emergency department visits in 2021. The health care cost for non-fatal falls in this group reached $80 billion in 2020, up sharply from 2015. While anticoagulants protect against heart and ...

"Breakthrough in progeria therapy: RNA scissors precisely target and remove mutant gene"

2025-07-29

Children who develop deep wrinkles, stunted growth, and rapidly aging bones and blood vessels as early as 1 to 2 years of age may be suffering from Hutchinson-Gilford Progeria Syndrome (HGPS), a rare and incurable genetic disorder that affects approximately one in eight million people. The average life expectancy for patients is just 14.5 years, and to date, no curative treatment exists. The only FDA-approved drug for progeria, lonafarnib (Zokinvy), comes at an extraordinary cost—approximately 1.4 billion ...

The Mount Sinai Hospital ranked among top in the nation by US News & World Report®

2025-07-29

FOR IMMEDIATE RELEASE Contact: Dan Verello Mount Sinai Press Office 212-241-9200 daniel.verello@mountsinai.org The Mount Sinai Hospital Ranked Among Top in the Nation by U.S. News & World Report® Five specialties ranked among Top 10; nine among Top 20 Mount Sinai West and Mount Sinai Morningside nationally ranked in 5 specialties New York, NY (July 29, 2025) – The Mount Sinai Hospital, the flagship hospital of Mount Sinai Health System, was listed among the nation’s top 20 hospitals for care excellence by U.S. News & World Report® for 2025-26, marking the 10th consecutive year the hospital has been listed on the publication’s “Honor ...

LAST 30 PRESS RELEASES:

American Pediatric Society announces Bruce D. Gelb, MD, as recipient of its prestigious 2026 APS John Howland Award

Friendships can ease loneliness for dementia caregivers

Researchers pose five guiding questions to improve the use of artificial intelligence in physicians’ clinical decision-making

Artificial intelligence takes the lead in revolutionizing cancer research explored at NFCR’s 2025 Global Summit and Award Ceremonies for Cancer Research and Entrepreneurship.