Arsenic exposure reduction and chronic disease mortality

JAMA

2025-11-17

(Press-News.org) About The Study: The findings of this study support an association between reduced arsenic exposure and improved health outcomes in populations exposed to contaminated drinking water.

Corresponding Authors: To contact the corresponding authors, email Yu Chen, PhD, (Yu.Chen@nyulangone.org) and Habibul Ahsan, MD, (hahsan@bsd.uchicago.edu).

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jama.2025.19161)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

# # #

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2025.19161?guestAccessKey=31ba480e-32a3-4310-8cf2-7fed9d077681&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=111725

END

ELSE PRESS RELEASES FROM THIS DATE:

Parasitic matricide, ants chemically compel host workers to kill their own queen

2025-11-17

Fukuoka, Japan—In the ruthless world of parasitic ants, taking over a host colony is a matter of life and death. The conventional understanding has been that an invading queen must physically fight and kill the resident queen to seize control. However, a new study published in Current Biology details a more sinister strategy: a parasitic ant queen that chemically manipulates the host colony’s workers into executing their own mother. “The initial discovery was made by my friend Taku Shimada, the first author of the paper, who has been passionate about ants since childhood and runs a popular blog called ‘AntRoom.’ He observed the colony infiltration ...

Clinical trials affected by research grant terminations at the National Institutes of Health

2025-11-17

About The Study: Approximately 1 in 30 trials and more than 74,000 trial participants were affected by grant funding disruptions. Affected trials disproportionately studied infectious diseases, prevention, and behavioral interventions, and were based in the Northeastern U.S. or in other countries. Because trials require sustained financial support to ensure operations and participant safety, unanticipated funding disruptions raise concerns about avoidable waste, data quality, and compromised ethical obligations to participants. Corresponding Author: To contact the corresponding author, Anupam B. Jena, MD, PhD, email jena@hcp.med.harvard.edu. To ...

Racial and ethnic disparities in cesarean birth trends in the United States

2025-11-17

About The Study: In this cohort study of births in the United States from 2012 to 2021, the rate of overall cesarean births decreased slightly over the study period. However, racial and ethnic disparities persisted, with increasing risk of primary cesarean births among non-Hispanic Black individuals compared with individuals from other racial and ethnic groups. Quality improvement efforts to reduce unnecessary cesarean births should address this inequity and the structural racism that drives it. Corresponding Author: To contact the corresponding author, Marie J. Boller, MD, email boller@ohsu.edu. To access the embargoed study: Visit our For The Media website ...

Light-intensity-dependent transformation of mesoscopic molecular assemblies

2025-11-17

Constructing out-of-equilibrium molecular assemblies that deviate from thermodynamic equilibrium is a central challenge in materials science. While numerous studies have reported the creation of such states using external energy sources such as chemical fuels or light, few systems can adaptively access different states depending on how much energy is input. Developing such systems could offer new design principles for advanced functional materials capable of flexibly adapting to environmental changes, much like biological systems. In a recent study published online in Chem on November 17, 2025, researchers in Japan reported a supramolecular polymer system that can produce out-of-equilibrium ...

Tirzepatide may only temporarily suppress brain activity involved in “food noise”

2025-11-17

PHILADELPHIA—A rare glimpse into the brain activity of a patient with obesity and loss of control eating on tirzepatide, marketed as Mounjaro and Zepbound, revealed that the medication suppresses signaling in the brain’s “reward center” thought to be involved in food noise – but only temporarily. Research suggests that the medication, a glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptor agonist, originally developed to manage Type 2 diabetes, may be able to treat a wide range of conditions ...

Do all countries benefit from clinical trials? A new Yale study examines the data

2025-11-17

Do All Countries Benefit From Clinical Trials? A New Study Examines the Data A new study led by Yale’s Jennifer Miller, PhD, found that medicines are not physically accessible in many of the countries where they are tested for FDA approval. The findings were published in JAMA Internal Medicine. For the study, researchers analyzed 172 FDA-approved medicines tested between 2015 and 2018 in nearly 90 countries. They found that five years after testing, only 24 percent of the medicines had received market authorization, or approval for distribution and patient access, in the countries where the clinical ...

Consensus on the management of liver injury associated with targeted drugs and immune checkpoint inhibitors for hepatocellular carcinoma (version 2024)

2025-11-17

The therapeutic landscape for hepatocellular carcinoma (HCC) has been revolutionized by the advent of molecular targeted therapies and immune checkpoint inhibitors (ICIs). While these systemic treatments have significantly improved outcomes for patients with intermediate and advanced HCC, their use is accompanied by a spectrum of adverse events, with drug-induced liver injury (DILI) being a common and potentially serious complication. To address this growing clinical challenge, the Chinese Society of Hepatology convened a multidisciplinary panel of experts to formulate the "Consensus on the Management of Liver Injury Associated with Targeted Drugs and Immune Checkpoint Inhibitors ...

Bridging the gap to bionic motion: challenges in legged robot limb unit design, modeling, and control

2025-11-17

In recent years, robots have increasingly become integral in enhancing human life, particularly with the growing demand for mobile robots with high payload-to-weight ratios and dynamic capabilities. Traditional wheeled or tracked robots are difficult to operate stably in complex real-world environments, which has driven research on legged robots. Legged robots leverage their distinctive “leg” structures to traverse obstacles and adapt to uneven terrain, demonstrating exceptional mobility when confronted with pronounced undulations or soft ground. ...

New study reveals high rates of fabricated and inaccurate citations in LLM-generated mental health research

2025-11-17

(Toronto, November 17, 2025) A new study published in the peer-reviewed journal JMIR Mental Health by JMIR Publications highlights a critical risk in the growing use of Large Language Models (LLMs) like GPT-4o by researchers: the frequent fabrication and inaccuracy of bibliographic citations. The findings underscore an urgent need for rigorous human verification and institutional safeguards to protect research integrity, particularly in specialized and less publicly known fields within mental health. Nearly 1 in 5 Citations Fabricated by GPT-4o in Literature Reviews The article, titled "Influence of Topic Familiarity and Prompt Specificity on Citation Fabrication in Mental ...

New 'heart percentile' calculator helps young adults grasp their long-term risk

2025-11-17

First tool to estimate percentiles of 30-year heart disease risk for adults ages 30–59 Aims to spark earlier prevention efforts amid rising diabetes and hypertension in young adults Men showed the highest long-term risk in national analysis Free online calculator is based on the American Heart Association’s PREVENT equations CHICAGO --- Just as saving for retirement starts early, so should protecting your heart. A new Northwestern Medicine study introduces a first-of-its-kind online calculator that uses percentiles to help younger adults forecast and understand their risk of a heart event over the next 30 years. ...

Arsenic exposure reduction and chronic disease mortality

ELSE PRESS RELEASES FROM THIS DATE:

LAST 30 PRESS RELEASES: