An important signaling system for developing social skills
2025-09-22
Endocannabinoids are similar to the cannabinoids present in cannabis, but they are found naturally in the body. Endocannabinoids—and cannabinoids—work through a signaling system that supports neurodevelopment, but whether manipulating this system prenatally has long-lasting effects remains unclear. In a new JNeurosci paper, researchers led by Ismael Galve-Roperh, from the Complutense University of Madrid, used mice to explore this unknown.
The researchers decreased expression of an endocannabinoid receptor in the prefrontal cortex of prenatal mice and assessed the impact of this manipulation on gene expression, ...
How the brain responds to bullying
2025-09-22
In a collaboration between Turun yliopisto and the University of Turku, researchers led by Birgitta Paranko and Lauri Nummenmaa explored the immediate effects of bullying on the brain.
As reported in their JNeurosci paper, the researchers measured neural and attentional responses while tweens (aged 11 to 14) and adults watched first-person videos of either people being bullied or more positive social interactions. For participants of all ages, bullying triggered distressful alarm states, activating social and emotional brain networks as well as autonomic threat response systems. Measuring eye-tracking responses and pupil sizes in a separate group of adults during video viewing supported ...
Koala stress linked to disease threat
2025-09-22
Australian researchers have revealed a clear relationship between stress and increased disease risk in koalas in South East Queensland and on the New South Wales North Coast.
A study led by Dr Michaela Blyton at The University of Queensland measured and tracked the level of koala retrovirus (KoRV) in groups of captive and wild koalas.
“We wanted to see what happened to their KoRV loads over time and how it related to chlamydial infection and levels of the stress hormones cortisol and corticosterone in their faeces,” Dr Blyton said.
“Virus load likely weakens the immune system, so those ...
Medical University of South Carolina professor to receive the 2025 Population Research Prize
2025-09-22
DALLAS, Sept. 22, 2025 — Daniel T. Lackland, Dr.P.H., FAHA, professor of epidemiology and neurology at the Medical University of South Carolina, will receive this year’s Population Research Prize at the American Heart Association’s Scientific Sessions 2025. The meeting, to be held Nov. 7-10, 2025, in New Orleans, is a premier global exchange of the latest scientific advancements, research and evidence-based clinical practice updates in cardiovascular science. Dr. Lackland will be presented with the award during the Presidential Session on Sunday, Nov. 9, 2025.
Dr. ...
Over 62,700 deaths associated with record-breaking heat during the summer of 2024 in Europe
2025-09-22
-. The year 2024 broke several temperature records: it was the hottest ever recorded, and its summer was also the warmest to date. A study led by the Barcelona Institute for Global Health (ISGlobal), a centre supported by the ”la Caixa” Foundation, has estimated that 62,775 heat-related deaths occurred in Europe between 1 June and 30 September of that year. These mortality figures are 23.6% higher than the approximately 50,800 estimated for the summer of 2023, and 8.1% lower than the nearly 67,900 estimated for the summer of 2022. These results have ...
Alcohol consumption per capita and suicide
2025-09-22
About The Study: In this systematic review and meta-analysis, an increase in alcohol consumption per capita was associated with an increase in the suicide mortality rate at the population level and that the association was similar across sexes. As such, alcohol consumption per capita may be a useful target to consider within comprehensive national suicide prevention strategies.
Corresponding Author: To contact the corresponding author, Shannon Lange, PhD, email shannon.lange@camh.ca.
To access the embargoed study: Visit our For The Media website at this ...
Prevalence and trajectories of perinatal anxiety and depression in a large urban medical center
2025-09-22
About The Study: The findings of this study underscore the need for routine and consistent screening, monitoring, and treatment of perinatal depression and anxiety. Women who received mental health services had faster reductions in depression over time, highlighting the potential impact for scalable and efficacious interventions during this critical period.
Corresponding Author: To contact the corresponding author, Nili Solomonov, PhD, email nis2051@med.cornell.edu.
To access the embargoed study: Visit our ...
JMIR Publications formally launches news & perspectives section with in-depth analysis of US research oversight
2025-09-22
(Toronto, September 22, 2025) JMIR Publications, a leading open access publisher of digital health research, today announced the publication of a scientific news article that marks the formal launch of its "News & Perspectives" section. The article, "Research Implications of Increased Political Oversight in the US," was written by Scientific News Editor, Kayleigh-Ann Clegg, PhD, who will be coordinating the development of JMIR Publications’ digital health news service.
Dr. Clegg's ...
Neural basis of schizophrenia and bipolar disorder found in brain organoids
2025-09-22
Pea-sized brains grown in a lab have for the first time revealed the unique way neurons might misfire due to schizophrenia and bipolar disorder, psychiatric ailments that affect millions of people worldwide but are difficult to diagnose because of the lack of understanding of their molecular basis.
The findings may eventually help doctors reduce human error when addressing those and other mental health disorders that currently can only be diagnosed with clinical judgement and treated with trial-and-error medication approaches.
Details about the insights appear today in APL Bioengineering.
“Schizophrenia and bipolar disorder are ...
How Ukraine keeps society going despite the war
2025-09-22
Despite being at war since February 2022, Ukraine has managed to maintain public services. A new study from Linköping University points to the collaboration between citizens and public authorities as a key factor in this. According to the researchers behind it, there are lessons to be learned for other countries should war or crisis come.
“Everyone, right down to the family and the individual, makes crucial decisions in times of deep crisis. It’s important that all actors are mobilised, ...
Urinary arsenic exposure and metabolic dysfunction-associated steatotic liver disease
2025-09-22
Background and objectives
While metabolic dysfunction-associated steatotic liver disease (MASLD) is associated with obesity, the cause of its rapidly rising prevalence is not well understood. In this study, we aimed to examine the association between arsenic exposure and MASLD in humans.
Methods
Urinary inorganic arsenic data from the National Health and Nutrition Examination Survey, 2011–2020, were used. These were combined with death certificate data from the National Death Index of the National Center for Health Statistics to ascertain mortality rates. Weighted linear regression and chi-squared ...
Crohn’s & Colitis Foundation and international partners launch GLIDE: An integrated global registry to advance IBD care
2025-09-22
New York, NY –September 22, 2025 – The Crohn’s & Colitis Foundation and an international consortium of leading IBD researchers, today announced the launch of the Global IBD Registry (GLIDE), a pioneering initiative designed to securely connect data from inflammatory bowel disease (IBD) registries around the world.
GLIDE will establish an integrated global research platform, enabling international researchers to analyze patient data at an unprecedented global scale while upholding the necessary standards in privacy and data sovereignty. Through secure, ethical international collaboration, GLIDE will accelerate insights into complex and unresolved ...
NFL CPR commitment awards Super Bowl tickets and $50,000 in school equipment
2025-09-22
DALLAS, Sept. 22, 2025 — Five students and five schools have been awarded special incentive prizes as part of a collaboration between the American Heart Association, devoted to changing the future to a world of healthier lives for all, and the National Football League (NFL) Foundation to encourage young people to learn Hands-Only cardiopulmonary resuscitation (CPR). Students who participated in the Association’s in-school programs, Kids Heart Challenge™ and American Heart Challenge™, during the 2024-25 school year and learned Hands Only CPR were eligible for incentive prize drawings ...
Availability of respite care almost triples a palliative care patient’s chance of dying at home
2025-09-22
Access to respite services for family caregivers increases a palliative care patient’s probability of dying at home almost threefold, according to a McGill University-led study.
Previous surveys suggest most Canadians with a serious illness would prefer to spend the end of their lives at home. In Quebec, fewer than one-in-10 palliative care patients die at home, a rate that has remained largely unchanged for two decades and lags behind the Canadian average of 15 per cent.
Funded by Quebec’s health ministry as part of its action plan for equitable access to quality palliative and end-of-life care, the study set out to find which ...
A deep look into the unique structure and behavior of confined water
2025-09-22
Despite being one of the most familiar substances on Earth, water holds many secrets that scientists are still working to understand. When confined to extremely small spaces—such as within certain proteins, minerals, or artificial nanomaterials—water behaves in ways that are drastically different from its bulk liquid form. These confinement effects are critical for many natural and technological processes, including regulating the flow of ions through cell membranes and the properties of nanofluidic systems.
One intriguing yet poorly understood state of ...
Study identifies hotspots of disease-carrying ticks in Illinois
2025-09-22
CHAMPAIGN, Ill. — Scientists analyzed the distribution of three potentially harmful tick species in Illinois, identifying regions of the state with higher numbers of these ticks and, therefore, at greater risk of infection with multiple tick-borne diseases.
The study found that, of the three species tracked, the lone star tick, Amblyomma americanum, is most prevalent in southern Illinois; the black-legged tick or deer tick, Ixodes scapularis, is more common in northern and central Illinois; and the dog tick, Dermacentor variabilis, dominates the central and ...
CHEST Is honored with two 2025 Power of Associations Awards
2025-09-22
GLENVIEW, IL— The American College of Chest Physicians (CHEST) has been recognized as a Power of Associations Silver Award winner by the American Society of Association Executives (ASAE) for two of its successful initiatives. CHEST’s First 5 Minutes®: Cultural Humility modules earned the Power of Conscious Inclusion Award, and the CHEST Community Connections program received the Power of Community Support Award.
The Power of Conscious Inclusion Award recognizes associations that advance equity and inclusion across workforce, governance, operations, ...
Ice dissolves iron faster than liquid water
2025-09-22
Ice can dissolve iron minerals more effectively than liquid water, according to a new study from Umeå University. The discovery could help explain why many Arctic rivers are now turning rusty orange as permafrost thaws in a warming climate.
The study, recently published in the scientific journal PNAS, shows that ice at minus ten degrees Celsius releases more iron from common minerals than liquid water at four degrees Celsius. This challenges the long-held belief that frozen environments slow down chemical reactions.
“It may sound counterintuitive, but ice is not a passive frozen block,” says ...
First evidence of a ‘nearly universal’ pharmacological chaperone for rare disease
2025-09-22
A study published today in Nature Structural & Molecular Biology is the first time researchers have shown evidence that a single drug, already licensed for medical use, can stabilise nearly all mutated versions of a human protein, regardless of where the mutation is in the sequence.
The researchers engineered seven thousand versions of the vasopressin V2 receptor (V2R), which is critical for normal kidney function, creating all possible mutated variants in the lab. Faulty mutations in V2R prevent kidney cells from responding to the hormone vasopressin, leading to the inability to concentrate urine and resulting ...
Beneath 300 kilometers: Natural evidence for nickel-rich alloys in the mantle
2025-09-22
Diamonds from South Africa’s Voorspoed mine have revealed the first natural evidence of nickel-rich metallic alloys forming deep in Earth’s mantle, between 280–470 km. A new study reveals that these inclusions coexist with nickel-rich carbonates, capturing a rare snapshot of a “redox-freezing” reaction whereby oxidized melts infiltrate reduced mantle rock. The growing diamond trapped both reactants and products of a diamond-forming reaction. This finding not only confirms long-standing predictions about mantle redox conditions but also highlights how such ...
New tool makes generative AI models more likely to create breakthrough materials
2025-09-22
The artificial intelligence models that turn text into images are also useful for generating new materials. Over the last few years, generative materials models from companies like Google, Microsoft, and Meta have drawn on their training data to help researchers design tens of millions of new materials.
But when it comes to designing materials with exotic quantum properties like superconductivity or unique magnetic states, those models struggle. That’s too bad, because humans could use the help. For example, after a decade of research into a class of materials that could revolutionize quantum computing, called quantum spin liquids, only a dozen material candidates have ...
Psychological distress common after a heart attack, may lead to future heart conditions
2025-09-22
Statement Highlights:
An estimated 33-50% of heart attack survivors may experience some form of psychological distress, including depression, anxiety, psychosocial stress or post-traumatic stress disorder (PTSD), which can affect physical recovery and long-term health.
People with persistent psychological distress lasting up to 12 months after a heart attack are nearly 1.5 times more likely to have a future cardiac event. More research is needed to confirm a direct cause-and-effect relationship between the conditions.
Recognizing ...
Study shows UV light can disable airborne allergens within 30 minutes
2025-09-22
Cats. Dust mites. Mold. Trees.
For people with allergies, even a brief whiff of the airborne allergens these organisms produce can lead to swollen eyes, itchy skin and impaired breathing.
Such allergens can persist indoors for months after the original source is gone, and repeated exposure can exacerbate, and even lead to, asthma.
What if you could just flip a switch and disable them? You can, according to new University of Colorado Boulder research.
“We have found that we can use a passive, generally safe ultraviolet light treatment to quickly inactivate airborne allergens,” said ...
Snapdragon secrets
2025-09-22
Every season, scientists from the Institute of Science and Technology Austria (ISTA) go on field trips to the Pyrenees. Their mission: gather snapdragon flowers to understand their genetic makeup. In a recently published study in Molecular Ecology, they show how nature uses color genes to keep two varieties of snapdragons distinct, even when they share the same habitat.
On the border between France and Spain lies a mountain range that spans from the Bay of Biscay to the Mediterranean Sea. The lush valleys and high peaks attract many tourists to the Pyrenees, ...
What are the recent trends in opioid prescribing for patients with cancer?
2025-09-22
A recent analysis reveals a modest decline from 2016 to 2020 in new and additional opioid prescriptions for patients with cancer. Among those patients with metastatic cancer, prescribing remained stable for those reporting any pain and declined steeply for those reporting no pain. The findings are published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society.
In response to the opioid crisis, public health efforts have sought to enact policies and regulations to reduce inappropriate opioid prescribing and prevent unsafe opioid use, including adverse outcomes such as opioid use disorder and opioid ...
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