RENTON, Wash. [Nov. 12, 2024] – New real-world data from Providence, Illumina (NASDAQ: ILMN), and Microsoft Research reveals that Comprehensive Genomic Profiling (CGP), when done early in a cancer patient’s diagnosis, leads to better personalized treatment and patient outcomes. The findings come out of the first two years of a five-year, real-world study, which was published today in the Journal of Clinical Oncology - Oncology Practice (JCO-OP).  Through a novel approach, the study employed pathologist-driven CGP testing ...

Strabismus, a misalignment of the eyes that occurs especially in children, has no bearing on intelligence or personality, but animated movies tend to use the condition to signify a villainous, dopey, or clumsy character, according to a new study from researchers at the University of Colorado School of Medicine. “When animators are figuring out what a character is going to look like, they have to decide on every little detail of that character's appearance, and so it's not by chance that an animated character happens to have strabismus,” says Michael ...

Researchers from Erasmus University and KU Leuven published a new Journal of Marketing study that examines how retailers respond when suppliers establish direct channels to reach end-consumers and how suppliers can take steps to avoid a backlash. The study, forthcoming in the Journal of Marketing, is titled “How Retailers Change Ordering Strategies When Suppliers Go Direct” and is authored by Michiel Van Crombrugge, Els Breugelmans, Femke Gryseels, and Kathleen Cleeren. Recently, Sony began selling PlayStation products through its PlayStation Direct online store in the UK, ...

Coral larvae reduce their metabolism and increase nitrogen uptake to resist bleaching in high temperatures, according to a study published November 12th in the open-access journal PLOS Biology by Ariana S. Huffmyer of the University of Washington, US, and colleagues. High ocean temperatures cause coral bleaching, which results from the disruption of the relationship between corals and their symbiotic algae, an increasing concern as global temperatures rise. However, relatively little research has examined the effects of high temperatures ...

AUSTIN, Texas — The federal tax gap — money people and companies owe Uncle Sam but fail to pay on time — has climbed to historic highs: $696 billion in 2022, according to the IRS. It’s money that, if recouped, could fund infrastructure or education or pay down government debt. One way to collect that money is through lawsuits prompted by corporate whistleblowers — often present or former employees who know a company’s finances and expose its transgressions. Federal law includes ...

Bioluminescence is the natural chemical process of light creation in some living creatures that makes fireflies flicker and some jellyfish glow. Scientists have long been interested in borrowing the secrets of these animals' light-producing genes to create similar effects in vertebrates, for a variety of biomedical applications. UC Santa Cruz Assistant Professor of Biomolecular Engineering Andy Yeh is designing completely artificial proteins that produce bioluminescence to serve as a non-invasive method for bioimaging, diagnostics, drug discovery, and more. A new paper published in the flagship journal Chem reports on a new series of bioluminescent ...

DETROIT — A recent study published in the journal Scientific Reports correlates higher levels of pollutant particulate matter to higher occurrences of head and neck aerodigestive cancer. The article, "Air Pollution Exposure and Head and Neck Cancer Incidence," is the work of a multi-institutional collaboration with researchers from Wayne State University, Johns Hopkins University and Mass General Brigham. The study was led by John Cramer, Ph.D., associate professor of otolaryngology, and John Peleman, M.D., medical resident in the Department of Otolaryngology, in the Wayne State University School of Medicine. They collaborated with Mass General Brigham, an integrated ...

The team was led by LSU Alumni Professor Heather McKillop, who first discovered wooden buildings preserved there below the sea floor, along with associated artifacts, and the only ancient Maya wooden canoe paddle in 2004. Her key collaborator, Assistant Professor Elizabeth Sills at the University of Texas at Tyler, began working with McKillop as a master’s student and then as a doctoral student at LSU. Since their initial discovery of wood below the sea floor in Belize, the team has uncovered an extensive pattern of sites that include “salt kitchens” for boiling ...

Every year around this time, California’s wildland firefighters hold their breath as hot, dry winds threaten to spread flames across the state. As such conflagrations grow in size and severity throughout the Western U.S., the strain on fire managers has intensified. A new report from Stanford University’s Climate and Energy Policy Program provides a blueprint for fostering a more inclusive, diverse and well-supported workforce to meet the increasing need for fire mitigation and management. “The wellbeing of the wildland fire workforce has ...

MBARI researchers have discovered a remarkable new species of sea slug that lives in the deep sea. Bathydevius caudactylus swims through the ocean’s midnight zone with a large gelatinous hood and paddle-like tail, and lights up with brilliant bioluminescence. The team published a description of the animal, nicknamed the “mystery mollusc,” in the journal Deep-Sea Research Part I. “Thanks to MBARI’s advanced underwater technology, we were able to prepare the most comprehensive description of a deep-sea animal ever made. We’ve ...

Researchers from the Oxford Martin Programme on Ethical Web and Data Architectures (University of Oxford) have reported findings from a paper exploring the motivations and challenges in running decentralised social media such as Mastodon, concluding such platforms offer potential for increased citizen empowerment in this digital domain. In their study, presented at the 27th ACM SIGCHI Conference on Computer-Supported Cooperative Work & Social Computing (CSCW) today, the researchers interviewed 16 administrators of Mastodon servers (otherwise known as instances), including those supporting marginalised and stigmatised communities. Their ...

“The classification of patients according to their level of frailty allows us to adjust prevention programs and focus our limited resources on the right action for the right person.” BUFFALO, NY- November 12, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), on October 24, 2024, Volume 16, Issue 20, titled, "Development and validation of an electronic frailty index in a national health ...

A research team led by UCLA Health Jonsson Comprehensive Cancer Center investigators has shown that that combining pembrolizumab, an immunotherapy drug, with standard chemotherapy can improve treatment outcomes for patients with small cell bladder cancer and small cell/neuroendocrine prostate cancer. Small cell carcinomas can arise in various tissues—including the bladder, prostate, lung, ovaries and breast—and are known for their rapid progression, tendency to relapse after initial treatment and poor overall survival ...

WASHINGTON, Nov. 12, 2024 – Indoor badminton courts are often used for high-stakes tournaments, but even an enclosed court can affect the path of a birdie. The airflow from a court’s heating, ventilation, and air conditioning (HVAC) system and cross ventilation plays a significant role in badminton. The lightweight feathered birdie passed between the players can be affected by low wind speed in the stadium. This is known as wind drift and has been at the center of multiple tournament controversies. While shutting ...

WASHINGTON, Nov. 12, 2024 – There are an estimated 7,000 languages spoken worldwide, each offering unique ways to express human emotion. But do certain emotions show regularities in their vocal expression across languages? In JASA, published on behalf of the Acoustical Society of America by AIP Publishing, an interdisciplinary team of linguists and bioacousticians led by Maïa Ponsonnet, Katarzyna Pisanski, and Christophe Coupé explored this by comparing expressive interjections (like “wow!”) ...

About The Study: In this cohort study of 1.2 million individuals ages 20 to 79 in South Korea, the risk of mortality with low income was most prominent among individuals with type 2 diabetes ages 20 to 39. These findings highlight the need for socioeconomic support to reduce income-related health disparities in younger individuals. Corresponding authors: To contact the corresponding authors, email Sin Gon Kim, MD, PhD (k50367@korea.ac.kr) and Nam Hoon Kim, MD, PhD (pourlife@korea.ac.kr). To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi: ...

About The Study: The frequency of discipline for physician-spread misinformation observed in this cross-sectional study was quite low despite increased salience and medical board warnings since the start of the COVID-19 pandemic about the dangers of physicians spreading falsehoods. These findings suggest a serious disconnect between regulatory guidance and enforcement and call into question the suitability of licensure regulation for combatting physician-spread misinformation. Corresponding author: To contact the corresponding author, Richard S. Saver, J.D., ...

COLUMBUS, Ohio – Suicide remains a pressing public health concern. An estimated 703,000 people die by suicide each year worldwide, according to The World Health Organization. In 2022, there were 49,449 suicides in the United States.  A new study found that brief cognitive behavioral therapy for suicide prevention – when delivered remotely via video telehealth – reduces suicide attempts and suicidal ideation. Researchers at The Ohio State University Wexner Medical Center and College of Medicine led the study that is published online in the journal JAMA Network Open. The randomized clinical ...

Researchers from the Mattiroli group have found that the way DNA is packaged in cells can directly impact how fast DNA itself is copied during cell division. They discovered that DNA packaging sends signals through an unusual pathway, affecting the cell’s ability to divide and grow. This opens up new doors to study how the copying of the DNA and its packaging are linked. These findings, published in Molecular Cell, may help scientists to find therapies and medicines for diseases such as cancer in the future. Chromatin as a guide Every day, our cells divide. Each time they need to copy both their DNA and the structure in which the DNA is packed. This packaging, ...

Seawater electrolysis has long been seen as a promising pathway for sustainable hydrogen production but has faced significant limitations due to chloride ion (Cl⁻) corrosion, which can degrade a catalyst's performance. Now scientists from the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese Academy of Sciences, along with their collaborators, have developed an efficient electrocatalyst called Co-N/S-HCS that demonstrates remarkable activity and stability in ...

LOS ANGELES — Researchers at City of Hope®, one of the largest and most advanced cancer research and treatment organizations in the United States, ranked among the nation’s top 5 cancer centers by U.S. News & World Report and a national leader in providing cancer patients with best-in-class, integrated supportive care programs, now understand why taking an investigational white button mushroom supplement shows promise in slowing and even preventing prostate cancer from spreading among men who joined ...

November 12, 2024—(BRONX, NY)— Marina Konopleva, M.D., Ph.D., director of the Leukemia Program and co-director of the Blood Cancer Institute at the National Cancer Institute-designated Montefiore Einstein Comprehensive Cancer Center (MECCC), has joined forces with Break Through Cancer, a collaborative medical research foundation that supports teams of scientists as they advance treatments for some of the world’s deadliest cancers. Dr. Konopleva will play a pivotal role in the Eradicating Minimal Residual Disease (MRD) in Acute ...

Patients with a small cranial nerve tumor that can cause hearing loss, vertigo, imbalance and ringing in the ears have typically been watched rather than proactively treated, as the risks of early intervention were thought to outweigh the benefits. However, even those patients benefit significantly from non-invasive stereotactic radiosurgery, a multicenter, international study led by UVA Health physicians has found. Doctors typically treat larger forms of the tumors, called vestibular schwannomas, while taking a “watch and wait” approach ...

Washington, November 12, 2024—As student absenteeism reaches record highs in schools across the United States, new research finds that student absences are linked to lower teacher job satisfaction, raising concerns that this may exacerbate growing teacher shortages. The findings were published today in Educational Researcher, a peer-reviewed journal of the American Educational Research Association. The study, by Michael Gottfried and Colby Woods at the University of Pennsylvania, and Arya Ansari at The Ohio State University, is the first ...

(WASHINGTON, November 12, 2024) – Continuous enrollment in Medicaid was associated with a lower rate of a late-stage lymphoma diagnosis in children and adolescents/young adults (AYAs). However, fewer than half of Medicaid-insured patients in these age ranges were continuously enrolled before diagnosis, according to a study published today in Blood Advances. Lymphoma – which is divided into two types, Hodgkin lymphoma (HL) and non-Hodgkin lymphoma (NHL) – is a cancer of the lymphatic system and ...