About The Study: This cross-sectional study including 426,000 children in Denmark found that body mass index (BMI) outcomes of COVID-19 pandemic–related control policies and restrictions were not exclusively observed among children with obesity, which suggests that pandemic-related mitigation policies targeting children and adolescents in all BMI categories are warranted. The findings of this study highlight differences among children of varying ages and BMI classes.  Corresponding Author: To contact ...

Picture juicy red tomatoes on the vine. What do you see? Some tomato varieties have straight vines. Others are branched. The question is why. New research from Cold Spring Harbor Laboratory (CSHL) provides the strongest evidence to date that the answer lies in what are called cryptic mutations. The findings have implications for agriculture and medicine, as they could help scientists fine-tune plant breeding techniques and clinical therapeutics. Cryptic mutations are differences in DNA that don’t affect physical traits unless certain other genetic changes occur at the same time. CSHL Professor & HHMI Investigator Zachary Lippman has ...

Enzymes catalyze chemical reactions in organisms - without which life would not be possible. Leveraging AlphaFold2 artificial intelligence, researchers at Charité – Universitätsmedizin Berlin have now succeeded in analyzing the laws of their evolution on a large scale. In the journal Nature*, they describe the parts of enzymes that change comparatively quickly and the parts that remain practically unchanged over time. These findings are relevant to the development of new antibiotics, for example. Enzymes resemble ...

A research team led by Eske Willerslev, professor at the University of Copenhagen and the University of Cambridge, has recovered ancient DNA from 214 known human pathogens in prehistoric humans from Eurasia. The study shows, among other things, that the earliest known evidence of zoonotic diseases – illnesses transmitted from animals to humans, like COVID in recent times – dates back to around 6,500 years ago, with such diseases becoming more widespread approximately 5,000 years ago. It is ...

The largest review of ‘gold standard’ antidepressant withdrawal studies to date has identified the type and incidence of symptoms experienced by people discontinuing antidepressants, finding most people do not experience severe withdrawal. In a systematic review and meta-analysis of previous randomised controlled trials relating to antidepressant withdrawal, a team of researchers led by Imperial College London and King’s College London concluded that, while participants who stopped antidepressants did experience an average of one more symptom than those who continued or were taking ...

Twisted materials—known as moiré structures—have revolutionized modern physics, emerging as today's "alchemy" by creating entirely new phases of matter through simple geometric manipulation. The term "moiré" may sound familiar—it describes the strange rippling patterns you sometimes see when photographing striped shirts or screens; in physics, the same underlying principle applies at the atomic scale.  Imagine taking two atomically thin sheets of either the same or different materials, stacking them up together, and rotating one layer slightly relative ...

The Moon's near and far sides exhibit striking asymmetry—from topography and crustal thickness to volcanic activity—yet the origins of these differences long puzzled scientists. China's Chang'e-6 mission, launched on May 3, 2024, changed this by returning 1,935.3 grams of material from the lunar farside's South Pole–Aitken Basin (SPA), the Moon's largest, deepest, and oldest known impact structure, measuring 2,500 kilometers in diameter. The samples arrived on Earth on June 25, 2024. Previous studies indicated that the SPA was formed by a colossal impact approximately 4.25 billion years ago, releasing energy greater than that of a trillion ...

In International Journal of Extreme Manufacturing, a new laser machining method that dynamically adapts its beam shape is proposed to fabricate microgrooves with complex, highly precise cross-sections—some with a root mean square error decreased to less than 0.5 μm when processing microgrooves with a width of 10 μm. The technique, developed by researchers at the Southern University of Science and Technology (SUSTech) in Shenzhen, China, could advance the production of microfluidic devices, sensors, and heat dissipation systems by allowing for rapid and scalable manufacturing of custom microstructures. Laser micromachining has long been constrained by the fundamental ...

“By synthesizing current insights on both RTK and non-RTK mediated resistance against anti-EGFR therapies, this review aims to guide future research and improve therapeutic strategies for these cancers.” BUFFALO, NY – July 9, 2025 – A new review was published in Volume 16 of Oncotarget on June 25, 2025, titled “Challenges and resistance mechanisms to EGFR targeted therapies in head and neck cancers and breast cancer: Insights into RTK dependent and independent mechanisms.” Researchers from the University of Cincinnati and Cincinnati ...

(Toronto, July 9, 2025) JMIR Publications invites submissions to a new theme issue titled “Ambient AI Scribes and AI-Driven Documentation Technologies” in its open access journal JMIR Medical Informatics. The premier, peer-reviewed journal is indexed in MEDLINE, PubMed, PubMed Central, DOAJ, Scopus, and the Science Citation Index Expanded (SCIE). Recent developments in generative artificial intelligence (AI) offer a promising pathway for reducing long-standing administrative burdens for physicians and clinicians. Specifically, there is a rapidly evolving field of ambient AI ...

Background and Aims Acute hepatitis E (AHE) in the elderly can lead to severe complications including liver failure and mortality, yet the epidemiological landscape remains poorly characterized. This study aimed to assess the burden, trends, and health inequalities of AHE among the elderly over the past three decades, and to further predict its changes by 2030. Methods Data on AHE in the elderly were obtained from the Global Burden of Disease 2021. The burden of AHE was analyzed by trends, decomposition, cross-country inequalities, and predictive analysis. Results In 2021, the global incidence and Disability-Adjusted Life Years (DALYs) for AHE among the elderly ...

A research team led by Dr. Kee Young Koo from the Hydrogen Research Department at the Korea Institute of Energy Research (President: Yi Chang-Keun, hereafter referred to as KIER) has developed a novel and more cost-effective method for synthesizing ammonia decomposition catalysts. This new approach enables more efficient hydrogen production from ammonia and is expected to make a significant contribution to the realization of a hydrogen economy. Composed of three hydrogen atoms and one nitrogen atom, ammonia has a high hydrogen content, ...

Mesophotic coral ecosystems (MCEs) are important coral ecosystems found between 30 and 150 meters deep in oceans worldwide including the Gulf of America. They support diverse marine life and important fisheries but remain poorly understood. Unlike shallow reefs, MCEs depend on nutrients from the deep ocean from upwelling or river plumes, like those from the Mississippi and Apalachicola rivers. These nutrient flows support growth of marine phytoplankton (i.e. tiny floating algae), which is an important source of organic matter (food) that sustains the corals and other marine species. However, scientists have ...

PULLMAN, Wash. -- Groundwater is declining across Eastern Washington’s complex, interconnected aquifer system, as people draw on it for irrigation, drinking and other uses at a pace that threatens its sustainability, according to a new study by a Washington State University researcher. In certain “hot spots” – such as the Odessa region and the Yakima Basin – the rates of decline are particularly significant, with groundwater levels dropping two to three feet a year or more. The data is built ...

Creatine is popularly known as a muscle-building supplement, but its influence on human muscle function can be a matter of life or death. “Creatine is very crucial for energy-consuming cells in skeletal muscle throughout the body, but also in the brain and in the heart,” said Chin-Yi Chen, a research scientist at Virginia Tech’s Fralin Biomedical Research Institute at VTC. Chen is part of a research team working to develop a technique that uses focused ultrasound to deliver creatine directly to the brain. The work, being conducted ...

CO2 concentrations vary widely depending on the source, ranging, for example, from about 0.04% in the atmosphere to about 10% in flue gases. Moreover, these gas streams contain a significant amount of O2 (about 10%), a potent oxidizing agent. To achieve carbon neutrality, it is necessary to develop a robust process that can convert CO2 over a wide concentration range, even in the presence of O2. However, current technology does not offer a single unified approach that can efficiently handle CO2 conversion from trace to high concentrations. To meet this challenge, researchers at Hokkaido University and collaborators ...

WASHINGTON—A new Scientific Statement released today by the Endocrine Society highlights potential research directions related to the pathogenesis of type 1 diabetes (T1D) that should help with the development of new and improved treatment options. Type 1 diabetes is a chronic disease where the body's immune system attacks and destroys insulin-producing cells in the pancreatic islet. Type 1 diabetes requires lifelong insulin administration and may result in complications such as eye, kidney, nerve, and heart disease. ...

PITTSBURGH, July 9, 2025 — During the menopause transition, only 1 in 5 women have optimal scores using the American Heart Association’s health-assessment tool, known as Life’s Essential 8 (LE8). Among the tool’s eight components, four of them — blood glucose, blood pressure, sleep quality and nicotine use — are key in driving future cardiovascular risks, with sleep being particularly crucial for long-term cardiovascular health. The findings – published today in Menopause – were made by researchers at the University of Pittsburgh, Albert Einstein College of Medicine and Baylor University. “Previously ...

It’s been recognized for some time that Alzheimer’s disease affects brain regions differently and that tau — a protein known to misbehave — plays an important role in the disease. Normally, tau helps stabilize neurons, but in Alzheimer’s disease, it begins to misfold and tangle inside neurons. It spreads across the brain forming toxic clumps that impair neuronal function and ultimately lead to cell death. Brain areas like the entorhinal cortex and hippocampus succumb early to tau tangles, while other areas, like the primary sensory cortices, remain resilient to the disease. In the quest to better understand this selective ...

COLUMBUS, Ohio – Have you ever wondered what kind of video content would most grab the attention of monkeys?   A new study of long-tailed macaques suggests the monkeys seem to like some of the same kind of content that humans do: videos featuring aggression and individuals they know.   “Humans and macaques are both social animals who have a fundamental need to belong,” said Brad Bushman, co-author of the study and professor of communication at The Ohio State University.   “It’s not surprising that they both would be most interested in the video content that may help ...

Newberry, FL – July 9, 2025 – Richard M. Peterson, MD, MPH, FACS, FASMBS, DABS-FPMBS, Professor and Chief of Metabolic and Bariatric Surgery at UT Health San Antonio, TX, has been elected the new president of the American Society for Metabolic and Bariatric Surgery (ASMBS), the nation’s largest professional organization of metabolic and bariatric surgeons and integrated health professionals focused on the treatment of obesity.  Dr. Peterson has been a member of the ASMBS for nearly 20 years and a board member since 2019. He has chaired the society’s ...

The Parsemus Foundation, a nonprofit dedicated to advancing pet health, today announced the publication of groundbreaking research on the safety and dosing of testosterone therapy for neutered male dogs. Published in BMC Veterinary Research, this pivotal study provides crucial data for veterinarians to treat "spay-neuter syndrome” - a collection of health and behavioral problems associated with hormone loss following sterilization. Results show that injectable testosterone can safely restore physiological hormone levels in neutered dogs, offering ...

BETHESDA, MD – July 9, 2025 | The American College of Medical Genetics and Genomics (ACMG) has released its highly anticipated 2025 update to the recommended minimum gene list for the reporting of secondary findings (SF) in clinical exome and genome sequencing: “ACMG SF v3.3 List for Reporting of Secondary Findings in Clinical Exome and Genome Sequencing: A Policy Statement of the American College of Medical Genetics and Genomics.” As part of its ongoing commitment to annual updates, ...

Why do rural adults and racial and ethnic minorities with vascular disease get major leg amputations more often? A new study out today in Epidemiology uses AI to solve the mystery, finding an unaccounted-for factor that researchers think points to implicit bias in the clinical decision-making process. “The AI model allowed us to distinguish among the many reasons behind these much higher rates of amputation among certain groups of people with vascular disease,” said Paula Strassle, ...

Many displays found in smartphones and televisions rely on thin-film transistors (TFTs) made from indium gallium zinc oxide (IGZO) to control pixels. IGZO offers high transparency due to its large bandgap (the gap existing between the valence and conduction bands), high conductivity, and can operate even in an amorphous (non-crystalline) form, making it ideal for displays, flexible electronics, and solar cells. However, IGZO-based devices face long-term stability issues, such as negative bias illumination stress, ...