Kidney organoid unlocks genetic cause of chronic kidney disease
2025-10-02
Chronic kidney disease (CKD) affects more than 700 million people worldwide and is caused by genetic and environmental factors, as well as existing medical conditions. Known genetic risk factors for CKD include mutations in a gene called APOL1. These are rare in most populations, but two risk variants are present in as much as 13 percent of people with West African origin and another 38% possess one copy (carriers). The causes for APOL1-mediated kidney disease (AMKD) are currently not well ...
Body composition and cardiometabolic risk in children
2025-10-02
About The Study: This repeated cross-sectional study provides a picture of the evolution of cardiometabolic risk factors in children over the last 30 years, showing that, in Spain, despite the concerning prevalences of excess weight, lipid parameters and blood pressure have improved over the studied period.
Corresponding Author: To contact the corresponding author, Sergio Nunez de Arenas-Arroyo, PhD, email sergio.nunezdearenas@uclm.es.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamanetworkopen.2025.35004)
Editor’s ...
Use of ambient AI scribes to reduce administrative burden and professional burnout
2025-10-02
About The Study: This multicenter quality improvement study found that use of an ambient artificial intelligence (AI) scribe platform was associated with a significant reduction in burnout, cognitive task load, and time spent documenting, as well as the perception that it could improve patient access to care and increase attention on patient concerns in an ambulatory environment. These findings suggest that AI may help reduce administrative burdens for clinicians and allow more time for meaningful work and ...
Newly recognized pathway could protect diabetics from hypoglycemia
2025-10-02
A new study by the University of California, Davis, shows how cells work together to avoid a sudden drop in blood sugar. Understanding these feedback loops could improve the lives of people with diabetes and help them avoid dangerous hypoglycemia.
The work was published Sept. 16 in Proceedings of the National Academy of Sciences.
People with diabetes must contend with the long-term risks of high blood sugar, such as blindness, kidney failure, and loss of circulation in the legs, which can ...
Studies find connection between impaired musical rhythm abilities and developmental speech-language disorders
2025-10-02
In a paper published in Nature Communications, researchers at Vanderbilt University Medical Center’s Department of Otolaryngology-Head and Neck Surgery leveraged two main studies — one focused on behavior and one focused on genetics — to highlight the correlation between participants’ musical rhythm abilities and developmental speech-language disorders.
These disorders include developmental language disorder, dyslexia and stuttering, among others.
Evidence showed that deficiency in musical rhythm perception is a “modest ...
Mount Sinai study highlights sex-based pelvic differences’ effect on spinal screw, rod placement during surgical procedures
2025-10-02
FOR IMMEDIATE RELEASE
Contact:
Dan Verello
Mount Sinai Press Office
212-241-9200
daniel.verello@mountsinai.org
Mount Sinai Study Highlights Sex-Based Pelvic Differences’ Effect on Spinal Screw, Rod Placement During Surgical Procedures
Findings aimed at tailoring treatment to patients’ specific anatomy
Journal: Spine Deformity
Title: Impact of sex on S2-alar-iliac pelvic screw position and lumbosacral rod alignment in adult spine deformity
Senior Author: James D. Lin, MD, MS, Assistant Professor of Orthopedics (Spine Surgery), ...
Virtual reality can reduce anxiety in patients undergoing interventional cardiovascular procedure
2025-10-02
Patients undergoing coronary angiography often experience anxiety both before and during the procedure, often treated by the administration of anti-anxiety medications. A new analysis being presented at the American College of Cardiology (ACC) Middle East 2025 Together with 16th Emirates Cardiac Society Conference found virtual reality (VR) effectively reduced anxiety during the procedure and had more stable vital signs than patients receiving standard care.
“Virtual reality offers an innovative solution to manage ...
Heart disease risk increases for US immigrants the longer they live in US
2025-10-02
Foreign born immigrants to the United States have a lower risk of cardiovascular disease than their U.S.-born counterparts; however, that advantage diminishes the longer they live in the U.S., according to a study presented at the American College of Cardiology’s Middle East 2025 Together with 16th Emirates Cardiac Society Conference taking place October 3-5, 2025, in Dubai, UAE.
“We see that as immigrants are exposed to U.S. dietary and lifestyle habits for prolonged periods of time, it has a negative effect on their heart health,” said Krishna Moparthi, a medical student at John. F. Kennedy University School of Medicine and co-author of the study. “There ...
Two abstracts using Bronchiectasis and NTM Research Registry data presented at European Respiratory Society Congress
2025-10-02
Miami (October 2, 2025) – The Bronchiectasis and NTM Association announced today that two abstracts using Bronchiectasis and NTM Research Registry data were presented at the European Respiratory Society Congress, held September 27-October 1, 2025, in Amsterdam, Netherlands.
The abstracts are:
“Exploring the overlapping burden of alpha-1 antitrypsin deficiency and bronchiectasis: insights from the US BRR,” which examined the role of alpha-1 antitrypsin deficiency in the development of bronchiectasis.
“Assessing ...
Sudan Ebola virus can persist in survivors for months, WSU study shows
2025-10-02
PULLMAN, Washington -- More than half of survivors of the Sudan Ebola virus still suffer serious health problems two years post-infection and the virus can persist in semen and breast milk for months after recovery, according to the first study examining the virus’s long-term effects.
The study, led by researchers at Washington State University, found 57.5% of the survivors of an outbreak in Uganda from 2022-23 reported ongoing and debilitating health issues that interfered with their daily lives. The detection of traces of the virus in semen and breast milk also raised concerns ...
The magnetic math of breast health
2025-10-02
Branching isn’t just for trees. This biological process occurs in animal development, enabling organs to perform complex functions. Branch-like structures form in lungs, kidneys, and breasts, among other places. Importantly, only in female mammary glands does most branching occur years after birth. It happens during puberty and again during pregnancy as milk ducts branch out in preparation for breastfeeding. Disturbances here have been linked to breast cancer. However, studying branching can be difficult and time-consuming.
Now, Cold Spring Harbor Laboratory (CSHL) researchers have developed a tool to quickly quantify changes in the branches of mouse mammary glands. ...
Six billion tonnes a second: Rogue planet found growing at record rate
2025-10-02
Astronomers have identified an enormous ‘growth spurt’ in a so-called rogue planet. Unlike the planets in our Solar System, these objects do not orbit stars, free-floating on their own instead. The new observations, made with the European Southern Observatory’s Very Large Telescope (ESO’s VLT), reveal that this free-floating planet is eating up gas and dust from its surroundings at a rate of six billion tonnes a second. This is the strongest growth rate ever recorded for a rogue planet, or a planet of any kind, providing valuable insights into how they form and grow.
“People may think ...
Young rogue planet displays record-breaking ‘growth spurt’
2025-10-02
A young rogue planet about 620 light-years away from Earth has experienced a record-breaking “growth spurt,” hoovering up some six billion tons of gas and dust each second over a couple of months.
A team of international researchers have explored changes in the planet’s growth and immediate surroundings. The observations provide insight into how rogue planets—free-floating planetary-mass objects that do not orbit stars—behave and grow in their infancy.
“We’ve caught this newborn rogue planet in the act of gobbling ...
The RESTART trial: a drug to block a toxic HIV molecule
2025-10-02
What if the presence of a well-known but misunderstood viral protein explains why some people living with HIV (PLWH) never recover their health, even with antiretroviral treatment?
Dr. Madeleine Durand and Andrés Finzi, researchers at the CRCHUM, Université de Montréal’s affiliated hospital research centre, will explore this through the launch of a groundbreaking clinical trial this fall.
Two studies, one approach
With the publication of a remarkable study in 2023, the two scientists and Mehdi Benlarbi, a PhD student in Finzi’s lab, showed a keen interest in the HIV molecule gp120. The virus is known to infect ...
New polymer designs for beyond-5G telecommunications
2025-10-02
With the rollout of fifth-generation (5G) telecommunications networks and 6G looming on the horizon, the demand for advanced materials that can handle high-frequency signals is rising rapidly. These systems use electromagnetic waves ranging from tens to hundreds of gigahertz (GHz), where signals are highly sensitive to transmission loss, interference, and distortion. To address these issues, scientists and engineers rely on special insulating materials, known as dielectrics, which help guide signals with minimal loss.
Polymer-based dielectrics are particularly attractive. ...
Hanbat National University study finds quantum computing can make homes smarter and greener
2025-10-02
Residential heating, ventilation, and air conditioning (HVAC) systems constitute a significant proportion of energy usage in buildings, necessitating energy management optimization. In this context, occupancy aware HVAC control is a promising option with 20-50% energy savings in homes. However, occupancy sensing technology suffers from long payback times, privacy issues, and poor comfort. Moreover, there is an increasing need for further advanced technologies that help regulate indoor air quality in addition to energy control.
To meet these expectations, scientists have recently turned to intelligent control methods such as ...
Tiny cell messengers in obese individuals accelerate Alzheimer’s-linked plaque buildup in the brain
2025-10-02
HOUSTON – Oct. 2, 2025 – Obesity has long been acknowledged as a risk factor for a wide range of diseases, but a more precise link between obesity and Alzheimer’s disease has remained a mystery – until now.
A first-of-its-kind study from Houston Methodist found that adipose-derived extracellular vesicles, tiny cell-to-cell messengers in the body, can signal the buildup of amyloid-β plaque in obese individuals. These plaques are a key feature of Alzheimer’s disease.
The study, “Decoding Adipose–Brain Crosstalk: Distinct Lipid Cargo in Human Adipose-Derived ...
Do elephants know when we're looking at them?
2025-10-02
Kyoto, Japan -- With their massive flapping ears and long trunks, it isn't hard to believe that elephants tend to rely on acoustic and olfactory cues for communication. They use gestures and visual displays to communicate as well, but we don't really know how much. Visual communication research has mainly focused on species that are primarily visual, like nonhuman primates.
A previous study demonstrated that African savanna elephants can recognize human visual attention based on a person's face and body orientation, but this had yet to be investigated in their Asian cousins. Asian elephants split from African elephants millions of years ago, so their behavior and cognition differ ...
Psilocybin targets brain circuits to relieve chronic pain, depression
2025-10-02
PHILADELPHIA— Researchers at Penn Medicine have identified specific brain circuits that are impacted by psilocybin—the active compound found in some psychedelic mushrooms—which could lead to new paths forward for pain and mental health management options. Chronic pain affects more than 1.5 billion people worldwide and is often deeply entangled with depression and anxiety, creating a vicious cycle that amplifies suffering and impairs quality of life. The study from the Perelman School of Medicine at the University of Pennsylvania- ...
MPs and public overestimate time left for climate action, study finds
2025-10-02
A new study has found that UK Members of Parliament (MPs) and the public overestimated the time left to meet a critical deadline for limiting global warming.
Researchers at the University of East Anglia (UEA) surveyed a representative sample of the previous House of Commons, and the public in Britain, Canada, Chile and Germany, on their knowledge of a well-publicised statement from the UN’s Intergovernmental Panel on Climate Change (IPCC).
It related to when global ...
Semaglutide and tirzepatide recommended as first-line treatment of obesity and most of its complications in new guidance from European Association for the Study of Obesity (EASO)
2025-10-02
Semaglutide or tirzepatide should be the first line treatment for people living with obesity and most of its complications, according to a new framework for the pharmacological treatment of obesity and its complications from the European Association for the Study of Obesity (EASO) to be published in the journal Nature Medicine. “Even though there are several options on the market, the reality is that semaglutide and tirzepatide are so effective that they should be the first choice in almost all cases,” says co-first author Dr Andreea Ciudin.
The authors are an international team of obesity experts led by the co-chairs of the EASO Obesity Management Working Group who are Dr ...
Generative AI is more efficient than nature at designing proteins to edit the genome
2025-10-02
Researchers at Integra Therapeutics, in collaboration with the Pompeu Fabra University (UPF) Department of Medicine and Life Sciences (MELIS) and the Center for Genomic Regulation (CRG), have designed and experimentally validated new synthetic proteins that can edit the human genome more efficiently than proteins provided by nature. This work, a global pioneer published today in the journal Nature Biotechnology, will be of great use in improving the current gene editing tools used in biotechnology research and personalized medicine by developing cellular (CAR-T) and gene therapies, especially to treat ...
ESMT Berlin study: ESG ratings show limited financial impact in the Gulf
2025-10-02
Firms in the Gulf region are increasingly expected to align with environmental, social, and governance (ESG) standards. Yet the link between ESG performance and financial outcomes remains ambiguous. A new study examines whether publicly listed companies in GCC member states that achieve high ESG ratings also deliver superior financial performance.
The study “ESG and financial performance in the Gulf Cooperation Council” was authored by Catalina Stefanescu-Cuntze, professor of management science and faculty lead of the Master in Analytics and Artificial Intelligence Program at ESMT Berlin, together with Rodrigo Tavares and Catarina Sá from Nova School ...
Scalable AI tracks motion from single molecules to wildebeests
2025-10-02
University of Michigan researchers have developed a tool powered by artificial intelligence that can help them examine the behavior of a single molecule out of a sea of information in the blink of an eye—or at least overnight.
Understanding the behavior of single molecules is important: it can lead to knowledge of different cellular processes or track how diseases begin and progress. To track the behavior of single molecules, researchers tag the molecules with what's called a fluorophore. They excite these fluorophores with a laser, then use powerful microscopes to follow the behavior of the tagged molecules over time.
But ...
Viewing teens more positively may help their school performance and strengthen family bonds
2025-10-02
Western cultures tend to view teens as moody, irresponsible, and rebellious. However, in China and in other cultures, the teen years are viewed more positively and seen as a time of learning how to become responsible and fulfilling family obligations. Previous research shows that fulfilling family obligations is an important marker of maturity and that as adolescents continue to improve their skills, they can contribute more to their families.
Past studies also show that when teens are seen ...
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